showing 36 of ~574560 from 574555 documents
Comment on “Androgens and women: COVID‐19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism”
2021
Ancient Immunity. Phylogenetic Emergence of Recognition-Defense Mechanisms.
2021
Although still scarcely considered by the majority of the biomedical world, invertebrates have greatly contributed to the elucidation of fundamental biological problems [...]
Septic arthritis due to Sneathia sanguinegens in a male. First case described in the scientific literature
2021
An 88-year-old male admitted with septic shoulder arthritis due to a gram-negative bacillus. The microorganism is identified by sequencing the 16 S rDNA gene as Sneathia sanguinegens. This is the first case described in the literature in a male, since so far only infections in women of childbearing age have been described.
Heart Failure with Preserved Ejection Fraction: An Urgent Need for Precision Medicine
2021
Heart failure with preserved (HFpEF) and mid-range ejection fraction (HFmrEF) constitute two heart failure categories, representing about 50–70% of the total [...]
Measuring Performance in the Luxury Industry: Is there a Difference in Performance Between the top and Bottom Players in the Industry?
2021
Abstract This paper presents a methodology that consists of a Z-score function applied on a set of indicators for the luxury industry and then standardized to obtain a ranking of the companies on a scale between 10 and 100. To measure the performance for the top 5 LVMH, Estee Lauder, Richemont, Kering, Essilor Luxottica, and bottom 5 Aeffe, Tribhovandas, Van de Velde, Mulberry, Trinity companies (based on Deloitte global ranking in 2019) in the luxury industry and to unveil which are the performance drivers. By applying this methodology it can be made a comparison in performance between the top and the bottom companies in the luxury industry. The performance score is calculated for ten year…
A BRIEF GUIDE TO THE ANATOMICAL DISSECTION OF THE STOMACH
2021
The purpose of this article is to write a short guide on the macroscopic anatomy of the stomach, describing its structures, its relationships within the abdominal cavity and the dissection methods used during the internship performed by a group of students from the University of Palermo, Palermo, Italy, at the University of Malta, Msida, Malta, during the Summer of 2018. Indeed, they had the opportunity to spend a period of two weeks at the department of Anatomy in the Maltese University for studying and practicing on some corpses, with the aim of improving their anatomical knowledge.
Impact of Platelet Reactivity in ACS Patients on Clinical Outcomes with Triple Antithrombotic Therapy
2021
Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients on oral anticoagulants (OAC) remains a clinical conundrum. In fact, combining an OAC with dual antiplatelet therapy (triple antithrombotic therapy, TAT) increases the risk of bleeding. Clopidogrel is the only thienopyridine recommended in TAT patients. Whether its response plays a relevant role in this setting remains uncertain. We aimed to evaluate the level of platelet reactivity inhibition (PRI) achieved by oral TAT in Acute Coronary Syndrome (ACS) patients undergoing PCI and its relationship with outcomes. We performed a multicenter prospective observational study and assessed PRI by vasodilator-st…
Mirel Bănică, Bafta, Devla şi Haramul. Studii despre cultura şi religia romilor [Bafta, Devla and Haram. Studies on the Culture and the Religion of t…
2021
How Intellectual Capital is Made?
2021
Abstract Worldwide organizations are compelled by global competition to achieve notable, inimitable results. In order to achieve this organizations must differentiate themselves from their competitors by using intangible resources that can get the long-term competitive advantage. This can be accomplished by identifying and managing the important elements of performance more effectively and efficiently. Consequently, organizations have to be aware and understand the connection between valuing intellectual capital and their performance. This article enhances the relationship between intellectual capital indicators and the measures to be taken in order to become strong innovators at european l…
Polyphenols and Pharmacological Screening of a Monarda fistulosa L. dry Extract Based on a Hydrodistilled Residue By-Product
2021
This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evaluate its safety and pharmacological properties. The total phenolic content (TPC) in the MFDE was 120.64 mg GAE/g. The high-performance liquid chromatography (HPLC) analysis showed the presence of a plethora of phenolic compounds, including hydroxycinnamic acids and flavone derivatives in the MFDE, with rosmarinic acid and luteolin-7-O-glucoside being the main components. With an IC50 value of 0.285 mg/mL, it was found to be a strong DPPH radical scavenger. …
Entrepreneurship Pedagogy
2021
With Latvia's education reforms, the demand for transversal skills in the education process has increased. Although there has been a growing call to educate pupils and students in a way that develops entrepreneurial skills, there is no defined methodology for how to do it, and the definitions of entrepreneurial skills and entrepreneurship pedagogy have no common foundation. This study, therefore, compiles research from various scientific publications and offers a theoretical framework for the concepts of entrepreneurial skill and entrepreneurial pedagogy. It also reviews the noble practices of diverse European countries and analyzes Latvia's higher education experience and examples of entre…
Dual Careers of Athletes During COVID-19 Lockdown
2021
This study aimed to investigate the student-athletes' capability to face the academic, sport, and social challenges during the coronavirus disease 2019 (COVID-19) lockdown and to disclose novel aspects of dual careers. A 32-item online survey encompassing demographic characteristics, sport and university engagement, support and dual-career benefits, physical activity, sitting time, and the time deemed necessary to recover the previous level of performance was developed. Four hundred sixty-seven student-athletes (males: 57%, females: 43%) from 11 countries, competing in 49 different sports (individual: 63.4%, team: 36.6%) at regional (17.5%), national (43.3%), and international (39.2%) level…
The Epidemiology of Hip and Knee Primary and Revision Arthroplasties during the COVID-19 Pandemic
2021
Background: The purpose of this study was to provide a comprehensive assessment of the impact of the COVID-19 pandemic on the epidemiology of primary and revision arthroplasties of the hip and knee joint. Methods: This study compared the data on knee and hip arthroplasty procedures from 2 hospitals (primary and revision) conducted in two periods: the period of the COVID-19 pandemic in Poland (from 4 March 2020 to 15 October 2020) and the corresponding period prior to the pandemic (from 4 March 2019 to 15 October 2019). We compared the epidemiological data, demographic data, and hospital stay duration data from these two periods. Results: Our analysis demonstrated that the total number of hi…
Evaluation of Landsat-8 TIRS data recalibrations and land surface temperature split-window algorithms over a homogeneous crop area with different phe…
2021
Abstract Successive re-calibrations were implemented in Landsat-8 TIRS data since launch. This paper evaluates the performances of both: (1) these re-calibrations, up to the last calibration update announced for TIRS data in the next Landsat Collection 2; and (2) single-channel (SC) corrections and split-window (SW) algorithms to retrieve land surface temperature (LST) from TIRS data. A robust and accurate multi-year (2014–2019) set of reference ground data were used, which included thermal infrared (TIR) radiance measurements taken along transects in a uniform and thermally homogeneous rice paddy area, but also emissivity measurements for the different ground covers at the site through the…
New trends in manufacturing systems research 2021
2021
New advances on the Aurignacian in the central Iberian Mediterranean basin
2021
Abstract This study aims to obtain a chronological and cultural framework of the Evolved Aurignacian in the central Iberian Mediterranean basin and find agreement between this framework and other sequences of the Iberian southeast. Over the last few years, there has been remarkable progress in the research of the Evolved Aurignacian sites in the Valencian area, making a review of the main characteristics of the technocomplex on a regional scale necessary. The recent fieldwork carried out in Cova de les Malladetes (Valencia) and in Cova de les Cendres (Alicante) have been key to understanding the lithic, osseous and ornament assemblages ascribed to the Evolved Aurignacian. Several Bayesian m…
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19
2021
Endothelial injury and microvascular/macrovascular thrombosis are common pathophysiological features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness severity of COVID-19. A variety of antithrombotic agents, doses, and durations of therapy are being assessed in ongoing randomized controlled trials (RCTs) that focus on outpatients, hospitalized patients in medical wards, and patients critically ill with COVID-19. This paper provides a perspective of the ongoing or completed RCTs related to antithrombotic strategies used in COVID-19, the opportunities and challenges for the clinical trial enterprise, and ar…
Self-esteem, quality of life, and physical activity in women with diagnosed endometriosis: a pilot study in an Italian sample
2021
Purpose. Endometriosis is a painful pathology impairing women's daily life. Several studies have shown that patients report low mental and physical quality of life, but no general evaluation of their self-esteem has been found. Studies concerning physical activity frequency present inconsistent results. Therefore, the current paper aims to compare life quality and selfesteem in women with endometriosis with the Italian normative data of the measures used. Methods. Overall, 36 women with diagnosed endometriosis treated in hospital completed a questionnaire detecting physical activity frequency, self-esteem, quality of life, and socioeconomic information. One sample t-test served to compare t…
The effect of contextual variables on the attacking style of play in professional soccer
2021
The aim of this paper was to investigate the interactive effects of contextual variables on the attacking style of play in professional soccer. 5849 team possessions from 40 random matches from Spanish La Liga and English Premier League 2017-2018 were analysed by means of multidimensional observation. Multilevel multivariate logistic regressions showed that home teams had higher odds of implementing fast attacks (p<.05) and lower odds of implementing direct attacks (p<.05) than combinative attacks. High-ranked teams presented lower odds of using direct attacks (p<.05) than combinative attacks in comparison with low-ranked teams, while playing against high-ranked opponents decreased the prob…
Long-Term Brain Disorders in Post Covid-19 Neurological Syndrome (PCNS) Patient
2021
In the recent pandemic disease, called COVID-19, the role of neurologists and neurobiologists represents a chance to study key features of brain infection and deepen neurological manifestations of COVID-19 and other coronavirus infections. In fact, many studies suggest brain damage during infection and persistent neurological symptoms after COVID-19 infection. Reverse transcription PCR test, antibody tests, Computed Tomography (CT) of the lung, and Magnetic Resonance (MR) of the brain of the patient were periodically performed during this case report for eight months after infection. The aim of this article is to describe the prolonged neurological clinical consequences related to COVID-19.…
The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients
2021
Abstract Background/objectives A dysregulated inflammatory profile plays an important role in coronavirus disease-2019 (COVID-19) pathogenesis. Moreover, the depletion of lymphocytes is typically associated with an unfavourable disease course. We studied the role and impact of p53 and deacetylase Sirtuin 1 (SIRT1) on lymph-monocyte homeostasis and their possible effect on T and B cell signalling. Methods Gene expression analysis and flow cytometry were performed on peripheral blood mononuclear cells (PBMC) of 35 COVID-19 patients and 10 healthy donors (HD). Inflammatory cytokines, the frequency of Annexin+ cells among CD3+ T cells and CD19+ B cell subsets were quantified. Results PBMC from …
Cover crop management and water conservation in vineyard and olive orchards
2021
Abstract Sustainability in orchard crops is an important goal for farmers, decision-makers and consumers. The United Nations Sustainable Development Goals emphasize the importance of the soils in the Earth System to achieve sustainability and accomplish the Land Degradation Neutrality Challenge. Within the world agriculture land, olive and vineyards are within the eldest crops in the world, and they are also the ones with the highest degree of soil degradation. Cover crops (CC) are widely accepted as sustainable crop management that reduces soil and water losses, restores organic matter, increases biodiversity and fertility in degraded agriculture soils. The agriculture land must shift into…
Mono- and Binuclear Copper(II) and Nickel(II) Complexes with the 3,6-Bis(picolylamino)-1,2,4,5-Tetrazine Ligand
2021
Four new compounds of formulas [Cu(hfac)2(L)] (1), [Ni(hfac)2(L)] (2), [{Cu(hfac)2}2(µ-L)]·2CH3OH (3) and [{Ni(hfac)2}2(µ-L)]·2CH3CN (4) [Hhfac = hexafluoroacetylacetone and L = 3,6-bis(picolylamino)-1,2,4,5-tetrazine] have been prepared and their structures determined by X-ray diffraction on single crystals. Compounds 1 and 2 are isostructural mononuclear complexes where the metal ions [copper(II) (1) and nickel(II) (2)] are six-coordinated in distorted octahedral MN2O4 surroundings which are built by two bidentate hfac ligands plus another bidentate L molecule. This last ligand coordinates to the metal ions through the nitrogen atoms of the picolylamine fragment. Compounds 3 and 4 are cen…
ASPERGILOSIS PULMONAR INVASIVA EN PACIENTES CON SINDROME DE DISTRÉS RESPIRATORIO POR COVID-19
2021
Resumen Los pacientes con COVID-19 que ingresan en una unidad de cuidados intensivos (UCI), tienen un alto riesgo de desarrollar infecciones secundarias, incluyendo infecciones fungicas invasivas como aspergilosis pulmonar invasiva (API). El objetivo principal fue el analisis de los casos con sospecha de COVID-19 Associated Pulmonary Aspergillosis (CAPA) en nuestra unidad. En estos pacientes realizamos cultivo micologico en el lavado broncoalveolar como metodos de aislamiento de Aspergillus sp. Se siguio el algoritmo AspICU para establecer el diagnostico de API probable. Ademas, considerando tambien relevante la positividad del antigeno de galactomanano. Se confirmo API probable en 3 de ell…
Being the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown
2021
Background: Family caregivers of patients with dementia are at high risk of stress and burden, and quarantine due to the coronavirus disease 2019 (COVID-19) pandemic may have increased the risk of psychological disturbances in this population. The current study was carried out during the national lockdown declared in March 2020 by the Italian government as a containment measure of the first wave of the coronavirus pandemic and is the first nationwide survey on the impact of COVID-19 lockdown on the mental health of dementia informal caregivers.Methods: Eighty-seven dementia centers evenly distributed on the Italian territory enrolled 4,710 caregiver–patient pairs. Caregivers underwent a tel…
Cuidados enfermeros a neonatos con encefalopatía hipóxico-isquémica en hipotermia terapéutica. Revisión bibliográfica
2021
Resumen Introduccion La encefalopatia hipoxico-isquemica es una de las principales causas de dano neurologico en el neonato. Actualmente, la hipotermia terapeutica es el tratamiento de eleccion para reducir la mortalidad y la discapacidad en los ninos que presentan esta patologia. Objetivo Identificar los cuidados enfermeros en recien nacidos con encefalopatia hipoxico-isquemica moderada a severa tratados con hipotermia terapeutica activa. Materiales y metodos Se realizo una revision de la literatura cientifica en diferentes bases de datos (PubMed, Lilacs, IBECS, Cinhal, OvidSP, Cuiden, Embase y Cochrane Plus) durante los ultimos 5 anos. La valoracion documental se realizo por pares y la ca…
COPD significantly increases cerebral and cardiovascular events in hypertensives
2021
AbstractEssential hypertension and chronic obstructive pulmonary disease often coexist in the same patient. The aim of this study was to evaluate whether the addition of chronic obstructive pulmonary disease modifies the risk of cardiovascular events in hypertensives. We enrolled 1728 hypertensives. Study outcomes included fatal and non-fatal cardiovascular stroke and myocardial infarction, and cardiovascular death. During a mean follow-up of 57 months there were 205 major adverse cardiovascular events (2.47 per 100 pts/yr): cardiac (n117; 1.41 per 100 pts/yr) and cerebrovascular (n = 77; 0.93 per 100 pts/yr). In hypertensives with chronic obstructive pulmonary disease we observed a greater…
Teoria, tecnica e didattica della pallacanestro in carrozzina
2021
Le capacità prestative degli individui, siano essi normodotati o con disabilità, è risaputo, migliorano notevolmente con l’aumentare del loro stato di salute psicofisico (Battaglia e coll. 2013). Un organismo stressato da una condizione patologica cronica necessità di svolgere un’attività fisica adattata allo stato di salute che lo caratterizza, poiché senza di essa finirebbe per perdere il senso più concreto dell'esistenza: “il movimento”. Il punto centrale non è dunque l'attività fisica di per sé o il tempo impiegato per svolgerla, ma piuttosto riguarda le modalità con le quali la si svolge. La scienza del movimento guarda all'individuo e alla sua complessità attraverso una valutazione ar…
The impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease
2021
This study investigated the impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease (NAFLD). A total of 63 eligible women randomly participated in the Nordic walking training (AEx, n = 33), or maintained their daily lifestyle (Con, n = 30) during intervention. Bone mineral content (BMC) and density (BMD) of whole body (WB), total femur (TF), femoral neck (FN), and lumbar spine (L2-4) were assessed by dual-energy X-ray absorptiometry. Serum osteocalcin, pentosidine, receptor activator of nuclear factor kappa-B ligand (RANKL) levels were analyzed by ELISA assay. After an 8.6-month intervention, the AEx group maintained their BM…
Formación del profesorado de educación física en el uso de aplicaciones tecnológicas
2021
La inclusión de las Tecnologías de la Información y Comunicación (TIC) en el ámbito educativo precisa de un profesorado con un nivel de competencia digital (CD) suficiente para enseñar al alumnado dicha tecnología. Paradójicamente, en la literatura existe una tendencia emergente por el estudio de la CD, mientras que el uso específico de las herramientas tecnológicas se está dejando de lado, especialmente en el campo de la educación física (EF). Por ello, el objetivo del presente trabajo fue valorar el empleo real de las aplicaciones educativas por parte del futuro profesorado de EF. Para ello, se aplicó el cuestionario CUTDEF (Cuestionario sobre conocimiento y uso de las TIC por los y las d…
Integrated use of unmanned aerial vehicle photogrammetry and terrestrial laser scanning to support archaeological analysis: The Acropolis of Selinunt…
2021
Southwestern Sicily is an area of infrequent seismic activity; however, some studies carried out in the archaeological Selinunte site suggest that, between the fourth century BC and the early Middle Ages, probably at least two earthquakes strucked this area with enough energy to damage and cause the collapse and kinematics of much of the architecture of Selinunte. Take into account that, in 2008, a noninvasive archaeological prospection and traditional data gathering methods along the Acropolis north fortifications were carried out. Following these first studies, after about 10 years, a new geophysical campaign was carried out. This second campaign benefited from the application of modern t…
Calibration of the underground muon detector of the Pierre Auger Observatory
2021
To obtain direct measurements of the muon content of extensive air showers with energy above $10^{16.5}$ eV, the Pierre Auger Observatory is currently being equipped with an underground muon detector (UMD), consisting of 219 10 $\mathrm{m^2}$-modules, each segmented into 64 scintillators coupled to silicon photomultipliers (SiPMs). Direct access to the shower muon content allows for the study of both of the composition of primary cosmic rays and of high-energy hadronic interactions in the forward direction. As the muon density can vary between tens of muons per m$^2$ close to the intersection of the shower axis with the ground to much less than one per m$^2$ when far away, the necessary bro…
Chemotherapy of metastatic colon cancer in France: A population-based study
2021
International audience; Aims: to describe, using data from a cancer registry in a well-defined French population, the therapeutic strategies and survival of patients with metastatic colon cancer (mCC).Methods: all patients with synchronous mCC diagnosed within the 2005-2014 period recorded in the digestive cancers registry of Burgundy were included.Results: 1286 mCC patients were included (57% male), of which 34.5% did not receive any antitumor treatment. Both, advanced age (≥75 years) and the Charlson comorbidity score ≥2 were significantly associated with the absence of antitumor treatment. Among the patients treated with chemotherapy, 59 and 33% received at least two and three lines, res…
Effects of obesity on periodontal tissue remodeling during orthodontic movement.
2021
Made available in DSpace on 2021-06-25T15:01:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) German Research Foundation (DFG) Introduction: Orthodontic movement triggers a sequence of cellular and molecular events that may be affected by different systemic conditions. This study evaluated the effect of obesity on rat periodontal tissue remodeling induced by mechanical orthodontic force. Methods: Thirty-two Holtzman rats were distributed into 4 groups: control, obesity induction (O), orthodontic movement (M), and obesity induction and orthodontic movement (OM). Obesity was induced by a high-fat diet for 90 days. Af…
Psychological Contract Violation or Basic Need Frustration? Psychological Mechanisms Behind the Effects of Workplace Bullying
2021
Workplace bullying is a phenomenon that can have serious detrimental effects on health, work-related attitudes, and the behavior of the target. Particularly, workplace bullying exposure has been linked to lower level of general well-being, job satisfaction, vigor, and performance and higher level of burnout, workplace deviance, and turnover intentions. However, the psychological mechanisms behind these relations are still not well-understood. Drawing on psychological contract and self-determination theory (SDT), we hypothesized that perceptions of contract violation and the frustration of basic needs mediate the relationship between workplace bullying exposure and well-being, attitudinal, a…
Soluble ST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction
2021
Abstract Background Identifying patients at risk of poor diuretic response in acute heart failure (AHF) is critical to make prompt adjustments in therapy. The objective of this study was to investigate whether the circulating levels of soluble ST2 predict the cumulative diuretic efficiency (DE) at 24 and 72 hours in patients with AHF and concomitant renal dysfunction. Methods and Results This is a post hoc analysis of the IMPROVE-HF trial, in which we enrolled 160 patients with AHF and renal dysfunction (estimated glomerular filtrate rate of Conclusions In patients with AHF and renal dysfunction at presentation, circulating levels of sST2 were independently and negatively associated with a …