showing 36 of ~574560 from 574555 documents
Comparative study of modelling the thermal efficiency of a novel straight through evacuated tube collector with MLR, SVR, BP and RBF methods
2021
Abstract Data-based methods are useful for accurate modelling of solar thermal systems. In this work, several artificial neural network (ANN) techniques are proposed to predict the thermal performance of an all-glass straight through evacuated tube solar collector. These are compared to support vector regression analysis. Extensive experimental data sets were collected for training the ANN models. Solar radiation intensity, ambient temperature, wind speed, mass flow rate and collector inlet temperature were selected as the input layer to predict the thermal efficiency of the solar collector. The prediction precision of the ANN models was compared to the multiple linear regression and suppor…
IL PROBLEMA DELLA RILEVANZA PENALE DELLA COLTIVAZIONE DI PIANTE DA STUPEFACENTI TRA OFFENSIVITA' E RAGIONEVOLEZZA
2021
The problem of criminal relevance of cultivation of narcotic plants can be considered an interesting opportunity to evaluate the interaction, on the interpretative level, related to the principles of harmfulness and reasonableness, understood as balancing criterion between opposite values. The author examines two jurisprudential interpretative ways to exclude the punishability for small “domestic” cultivations of narcotic plants. The first attempt was to contest the constitutional legitimacy of Article 75 of the d.P.R. 309/1990, because it doesn’t include, as an administrative offence, minimal cultivations for the purpose of personal consumption. The second attempt was to exclude any puniti…
Frontispiece: Recent Advances in Enantioselective Desymmetrizations of Prochiral Oxetanes
2021
Pengembangan Model PBL Terintegrasi Kognitif Moral Pada Mahasiswa PGSD UNIPA Surabaya
2021
The research aims to produce learning tools for Moral Cognitive Integrated PBL Learning Model, knowing the level of moral cognitive of PGSD Unipa Surabaya students and the influence of Moral Cognitive Integrated PBL Learning Model on Moral Cognitive of PGSD Unipa Surabaya Students. This type of research is R&D development research that has been simplified into three stages, namely preliminary studies, model development and model validation. The study population was all students of PGSD Class 2020 which consisted of seven classes, namely classes A-F. Whereas the sample of this study were students of PGSD Class 2020 Class A and Class F. The results of the study were the validation results…
Interactional means of teaming up: enacting the features of contemporary working life in a theater performance
2021
Abstract The article examines how the aspects of the social world are enacted in a theater play. The data come from a videotaped performance of a professional theater, portraying a story about a workplace organization going through a personnel training program. The aim of the study is to show how the core theme of the play – the teaming up of the personnel – is constructed in the live performance through a range of interactional means. By focusing on four core episodes of the play, the study on the one hand points out to the multiple changes taking place both within and between the different episodes of the play. On the other hand, the episodes of collective action involving the semiotic re…
Behavioral and Brain Measures of Morphological Processing in Children With and Without Familial Risk for Dyslexia From Pre-school to First Grade
2021
School-age reading skills are associated with and predicted by preschool-age cognitive risk factors for dyslexia, such as deficits in phonological awareness, rapid automatized naming, letter knowledge, and verbal short-term memory. In addition, evidence exists that problems in morphological information processing could be considered a risk factor for dyslexia. In the present study, 27 children at pre-school age and the same 27 children at first grade age performed a morphological awareness task while their brain responses were measured with magnetoencephalography. Our aim was to examine how derivational morphology in Finnish language, and concomitant accuracy and reaction times are associat…
All-atom simulations to studying metallodrugs/target interactions.
2021
Abstract Metallodrugs are extensively used to treat and diagnose distinct disease types. The unique physical–chemical properties of metal ions offer tantalizing opportunities to tailor effective scaffolds for selectively targeting specific biomolecules. Modern experimental techniques have collected a large body of structural data concerning the interactions of metallodrugs with their biomolecular targets, although being unable to exhaustively assess the molecular basis of their mechanism of action. In this scenario, the complementary use of accurate computational methods allows uncovering the minutiae of metallodrugs/targets interactions and their underlying mechanism of action at an atomic…
Fractional viscoelastic characterization of laminated glass beams under time-varying loading
2021
Abstract Laminated glass is a composite made of elastic glass layers sandwiching thin viscoelastic polymeric interlayers. There are several types of polymers, traditionally modelled as linear viscoelastic materials using a Prony’s series of units in the Maxwell-Wiechert arrangement. We show that one single element with fractional viscoelastic properties (two constitutive parameters that depend on environmental temperature), is sufficient to provide an accurate description of the polymer response under arbitrary time-varying actions. This is a great advantage over the classical viscoelastic characterization, which requires at least 10–15 terms in the Prony’s series, each one characterized by…
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2021
Aging and diabetes lead to protein glycation and cause dysfunction of collagen-containing tissues. The accompanying structural and functional changes of collagen significantly contribute to the development of various pathological malformations affecting the skin, blood vessels, and nerves, causing a number of complications, increasing disability risks and threat to life. In fact, no methods of non-invasive assessment of glycation and associated metabolic processes in biotissues or prediction of possible skin complications, e.g., ulcers, currently exist for endocrinologists and clinical diagnosis. In this publication, utilizing emerging photonics-based technology, innovative solutions in mac…
Lessons learned on student engagement from the nature of pervasive socio‐digital interests and related network participation of adolescents
2021
The rise of modern socio-digital technologies has fundamentally changed the everyday environments in which young people communicate with each other and cultivate interests. To gain a more sophisticated understanding of this phenomenon, this study provides in-depth, qualitative insights into adolescents’ experiences of their socio-digital developmental ecologies. The 15 interview participants were recruited based on a previously conducted questionnaire. The semi-structured theme interview addressed the socio-digital aspects of the participants’ interest-driven behaviours and related networks with the aid of participant-generated egocentric maps. The data not only qualitatively enrich the pic…
Le syndic de propriété
2021
Préface de Hugues Périnet-Marquet (refonte de l'ouvrage de G.Vigneron); International audience
Integrated use of unmanned aerial vehicle photogrammetry and terrestrial laser scanning to support archaeological analysis: The Acropolis of Selinunt…
2021
Southwestern Sicily is an area of infrequent seismic activity; however, some studies carried out in the archaeological Selinunte site suggest that, between the fourth century BC and the early Middle Ages, probably at least two earthquakes strucked this area with enough energy to damage and cause the collapse and kinematics of much of the architecture of Selinunte. Take into account that, in 2008, a noninvasive archaeological prospection and traditional data gathering methods along the Acropolis north fortifications were carried out. Following these first studies, after about 10 years, a new geophysical campaign was carried out. This second campaign benefited from the application of modern t…
Effects of Home-Based Physical Exercise on Days at Home and Cost-Effectiveness in Pre-Frail and Frail Persons: Randomized Controlled Trial.
2021
Objectives: Frailty increases the risks of hospitalization, institutionalization, and death. Our objective was to study the effects of home-based physical exercise on the number of days spent at home among pre frail and frail persons, versus usual care. In addition, utilization and costs of health care and social services, cost-effectiveness, and health-related quality-of-life (HRQoL) were explored. Design: Randomized controlled trial, with year-long supervised exercise for 60 minutes twice a week versus usual care. Follow-up for 24 months after randomization. Setting and Participants: A sample of 299 home-dwelling persons in South Karelia, Finland. Main inclusion criteria: >65 years, meeti…
Impact of Right Ventricular Dysfunction on Outcomes After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation
2021
OBJECTIVES This study sought to assess the impact of right ventricular dysfunction (RVD) as defined by impaired right ventricular-to-pulmonary artery (RV-PA) coupling, on survival after edge-to-edge transcatheter mitral valve repair (TMVR) for severe secondary mitral regurgitation (SMR). BACKGROUND Conflicting data exist regarding the benefit of TMVR in severe SMR. A possible explanation could be differences in RVD. METHODS Using data from the EuroSMR (European Registry on Outcomes in Secondary Mitral Regurgitation) registry, this study compared the characteristics and outcomes of SMR patients undergoing TMVR, according to their RV-PA coupling, assessed by tricuspid annular plane systolic e…
To achieve a sense of rightness: The joint role of Not Just Right Experiences and Intolerance of Uncertainty in Obsessive-Compulsive Disorder
2021
Abstract Background/Objective Not Just Right Experiences (NJREs) are currently considered as one of the motivators of Obsessive-Compulsive Disorder (OCD), but the ways through which NJREs affect OCD symptoms remains unclear. The aim of the present study was to examine the putative mediational role of Intolerance of Uncertainty (IU) in the association between NJRE severity and OCD symptoms in patients with OCD. Method Sixty-two patients with OCD completed self-report measures of NJREs, OCD symptoms, and IU. Results IU mediated the relationship between NJRE severity and OCD symptoms. Furthermore, NJRE severity emerged as moderator of the path, suggesting that the mediational role of IU is str…
Psychometric evaluation of the Persian version of the diabetic foot self-care questionnaire in Iranian patients with diabetes
2021
AbstractBackgroundDiabetic foot self-care refers to a group of self-management behaviors that can reduce the incidence of foot ulcers and amputations. It is necessary to have a valid and reliable standard tool to measure foot self-care in diabetic patients. This study aimed to evaluate the psychometric properties of the Persian version of the Diabetic Foot Self-Care Questionnaire of the University of Malaga, Spain (DFSQ-UMA) in Iran.MethodsThis cross-sectional study was conducted with 407 diabetic patients who were selected using a convenient sampling method. Construct validity was assessed by exploratory (with 207 patients) and confirmatory (with 200 patients) factor analyses. Internal con…
Una teoria generale del comportamento sociopatico
2021
General theory of behavior sociopath.
Comments on "Identifying inconsistency in network meta-analysis: Is the net heat plot a reliable method?"
2021
One of the biggest challenges for network meta‐analysis is inconsistency, which occurs when the direct and indirect evidence conflict. Inconsistency causes problems for the estimation and interpretation of treatment effects and treatment contrasts. Krahn and colleagues proposed the net heat approach as a graphical tool for identifying and locating inconsistency within a network of randomized controlled trials. For networks with a treatment loop, the net heat plot displays statistics calculated by temporarily removing each design one at a time, in turn, and assessing the contribution of each remaining design to the inconsistency. The net heat plot takes the form of a matrix which is displaye…
Active biopackaging produced from by‐products and waste from food and marine industries
2021
The agro‐food industry cannot today do without packaging to preserve and above all market its products. Plastic materials coming mainly from petrochemicals have taken a predominant place in the food packaging sector. They have become indispensable in many sectors, from fresh to frozen products, from meat and dairy products to fruit and vegetables or almost‐ready meals. Plastics are cheap, their lightness reduces transport costs, and their convenience is fundamental for out‐of‐home catering. However, plastics pose serious end‐of‐life issues. The development of materials that are more respectful of the consumer and the environment has become a major issue. In addition, the agro‐food industrie…
Psychological Profile in Female Cyclists and Its Relationship with Age, Training Parameters, Sport Performance, and Injury Incidence.
2021
Previous studies have highlighted the importance of psychology on sports performance and its relationship with the incidence of sport injuries. The objectives of the present investigation were: (1) to analyze the psychological profile of female cyclists as a function of age, training parameters, sport performance, and injuries suffered and (2) to design a model to predict their psychological profile. Sixty-one female cyclists participated in the study. Differences were found as a function of a competitive category for team cohesion (F = 5.035
Induction of stress resistance and extension of lifespan in Chaenorhabditis elegans serotonin-receptor knockout strains by withanolide A
2021
Abstract Introduction Approximately 300 million people worldwide suffer from depression. The COVID-19 crisis may dramatically increase these numbers. Severe side effects and resistance development limit the use of standard antidepressants. The steroidal lactone withanolide A (WA) from Withania somnifera may be a promising alternative. Caenorhabditis elegans was used as model to explore WA's anti-depressive and anti-stress potential. Methods C. elegans wildtype (N2) and deficient strains (AQ866, DA1814, DA2100, DA2109 and MT9772) were used to assess oxidative, osmotic or heat stress as measured by generation of reactive oxygen species (ROS), determination of lifespan, and mRNA expression of …
Online measurement of floc size, viscosity, and consistency of cellulose microfibril suspensions with optical coherence tomography
2021
AbstractIn this study, cellulose microfibril (CMF) suspensions were imaged during pipe flow at consistencies of 0.4%, 1.0%, and 1.6% with optical coherence tomography (OCT) to obtain images of the structure and the local velocity of the suspension. The viscosities obtained by combining pressure loss measurement with the OCT velocity data showed typical shear thinning behavior and were in excellent agreement with viscosities obtained with ultrasound velocity profiling. The structural OCT images were used to calculate the radial and the axial floc sizes of the suspension. A fit of power law to the geometrical floc size–shear stress data gave the same power law index for all consistencies, sug…
Serotoninergic Modulation of Phototactic Variability Underpins a Bet-Hedging Strategy in Drosophila melanogaster
2021
When organisms’ environmental conditions vary unpredictably in time, it can be advantageous for individuals to hedge their phenotypic bets. It has been shown that a bet-hedging strategy possibly underlies the high inter-individual diversity of phototactic choice in Drosophila melanogaster. This study shows that fruit flies from a population living in a boreal and relatively unpredictable climate have more variable variable phototactic biases than fruit flies from a more stable tropical climate, consistent with bet-hedging theory. We experimentally show that phototactic variability of D. melanogaster is regulated by the neurotransmitter serotonin (5-HT), which acts as a suppressor of the var…
Il rescaling e la flessibilità geografica del modello territoriale reticolare policentrico
2021
Con l’obiettivo di alimentare il dibattito scientifico-disciplinare in corso sulle modalità con cui i territoti devono essere governati e con quali strumenti e politiche, il contributo intende proporre alcune riflessioni sulle relazioni che stanno caratterizzando il processo evolutivo dei territori, sulle forme di cooperazione necessarie e sui confini che devono essere re-interpretati e ri-definiti, e propone il policentrismo reticolare come modello di sviluppo territoriale da perseguire per affrontare le sfide del rescaling. I primi due paragrafi affrontano specificatamente le questioni legate ai processi di rescaling e alle questioni ancora aperte relativamente alla governance territorial…
Credit and financial markets in the Iberian Peninsula at the end of the Middle Ages. Historiographic production and recent developments
2021
El artículo examina la trayectoria de los estudios sobre el crédito y los mercados financieros en la Península Ibérica a finales de la Edad Media, desde los primeros trabajos sobre la usura y el préstamo a interés, fundamentalmente judío, en la primera mitad del siglo XX, hasta las líneas de investigación más recientes, que se ramifican en diversas direcciones, desde el marco teórico, doctrinal y legal del mercado del crédito y el estudio de los diferentes instrumentos financieros –préstamo a interés, crédito comercial y bancario, crédito a largo plazo en forma de censales y censos consignativos– a la deuda pública y el crédito privado, especialmente el crédito rural. Todos estos estudios m…
Un Parco nella Sicilia più nascosta
2021
Le aree interne della Sicilia sono caratterizzate, oltre che dalle tipiche crisi delle aree marginali, da altri fattori peculiari quali una costante arretratezza tecnologica e uno disfattismo di gattopardesca memoria. Esse sono anche però il luogo ove lo sviluppo locale potrebbe riportare i suoi migliori esiti, trasformandole da luoghi del sottosviluppo in luoghi di rinnovata e viva identità. Ciò in virtù dalla immensa potenzialità che luoghi naturali come i Parchi possiedono intrinsecamente per avviare uno sviluppo sostenibile che riesca a mantenere le componenti identitarie e paesaggistiche di un luogo e al contempo risollevarne le sorti. Il caso studio, ivi presentato, riguarda il Parco …
Staying at the front line of literature: How can topic modelling help researchers follow recent studies?
2021
Staying at the front line in learning research is challenging because many fields are rapidly developing. One such field is research on the temporal aspects of computer-supported collaborative learning (CSCL). To obtain an overview of these fields, systematic literature reviews can capture patterns of existing research. However, conducting systematic literature reviews is time-consuming and do not reveal future developments in the field. This study proposes a machine learning method based on topic modelling that takes articles from a systematic literature review on the temporal aspects of CSCL (49 original articles published before 2019) as a starting point to describe the most recent devel…
Respuesta a “Fumador, exfumador y COVID-19”
2021
Development of Antioxidant Protein Extracts from Gilthead Sea Bream (Sparus aurata) Side Streams Assisted by Pressurized Liquid Extraction (PLE)
2021
The pressurized liquid extraction (PLE) technique was used, for the first time, to obtain protein extracts with antioxidant activity from side streams (muscle, heads, viscera, skin, and tailfins) of gilthead sea bream (Sparus aurata) in order to give added value to these underutilized matrices. Extraction conditions previously optimized for sea bass (Dicentrarchus labrax) side streams were applied. Protein recovery percentages were 22% (muscle), 33% (heads), 78% (viscera), 24% (skin), and 26% (tailfins), which represented an increase of 1.2–4.5-fold compared to control samples (extraction by stirring). The SDS-PAGE profiles revealed that PLE-assisted extraction influenced protein molecular …
Relationship between physical activity and predicted home presenteeism among participants with depressive symptoms with and without clinical depressi…
2021
Background and objectives Depression can pose a major threat to an individual’s ability to cope with daily activities. The aim of this study was to explore the relationship between physical activity (PA) and predicted home presenteeism (PHP) among depressive participants. The relationship between PHP and the severity of depressive symptoms was also investigated. Methods A total of 760 participants with depressive symptoms (DS) aged ≥35 years participated in this study. The study was conducted between 2008 and 2016 in municipalities within the Central Finland Hospital District. DS were determined with the 21-item Beck Depression Inventory (BDI-21) with a cutoff score ≥10, and psychiatric dia…
Reconstructing early Holocene seasonal bottom-water temperatures in the northern North Sea using stable oxygen isotope records of Arctica islandica s…
2021
The knowledge of seasonal temperature variability in the ocean is essential for understanding climate and its response to forcing factors. Time intervals with highly dynamic climate and increased seasonal forcing such as the early Holocene are of particular interest. Yet, the temporal resolution of most existing climate records is not sufficient to reconstruct temperature seasonality. Here, we present the first seasonally resolved, early Holocene, bottom-water temperature record from the Viking Bank in the northern North Sea. The reconstruction is based on the stable oxygen isotope data (δ18Oshell) of two crossdated, radiocarbon-dated subfossil shells of Arctica islandica (Bivalvia). Oxygen…
Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome
2021
Simple Summary Lifestyle modifies cancer risk in the general public. How lifestyle modifies cancer risk in individuals carrying the inherited pathogenic gene variants in DNA mismatch repair genes (Lynch syndrome) remains understudied. We conducted a retrospective study with cancer register data to investigate associations between body weight, physical activity, and cancer risk among Finnish Lynch syndrome carriers (n = 465, 54% women). The results of our study indicated that longitudinal weight gain increases cancer risk, whereas being highly physically active during adulthood could decrease cancer risk in men. Further, women were observed to be less prone to lifestyle-related risk factors …
Rapamycin-Loaded Polymeric Nanoparticles as an Advanced Formulation for Macrophage Targeting in Atherosclerosis
2021
Recently, rapamycin (Rapa) represents a potential drug treatment to induce regression of atherosclerotic plaques
Neuromuscular Training Warm-up Prevents Acute Noncontact Lower Extremity Injuries in Children’s Soccer : A Cluster Randomized Controlled Trial
2021
Background: Prevention of sports injuries is essential in youth, as injuries are associated with less future physical activity and thus greater all-cause morbidity. Purpose: To investigate whether a neuromuscular training warm-up operated by team coaches is effective in preventing acute lower extremity (LE) injuries in competitive U11-U14 soccer players. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: Twenty top-level U11 to U14 soccer clubs in Finland were randomized into intervention and control groups and assessed for 20 weeks. Participants included 1403 players (280 female, 1123 male; age range, 9-14 years): 673 players (44 teams) in the intervention group and …
Viaggi internazionali ai tempi del COVID-19: quale ruolo per il diritto internazionale?
2021
Since the beginning of the COVID-19 pandemic, States and corporations have been debating over what measures could be implemented in order to progressively ease restrictions on international travel: the proposals made included implementing an immunity passport, or, with the development and production of vaccines, a vaccination certificate. The article analyses the possibility of adopting these measures in conformity with International Health Regulations (IHR) and the International Covenants on Human Rights. Finally, it formulates a hypothesis for the revision of International Health Regulations whilst giving them an interpretation that is harmonized with human rights norms.
Exploring Super-Earth Surfaces: Albedo of Near-Airless Magma Ocean Planets and Topography
2021
In this paper we propose an analytic function for the spherical albedo values of airless and near-airless magma ocean planets (AMOPs). We generated 2-D fractal surfaces with varying compositions onto which we individually threw 10,000 light rays. Using an approximate form of the Fresnel equations we measured how much of the incident light was reflected. Having repeated this algorithm on varying surface roughnesses we find the spherical albedo as a function of the Hurst exponent, the geochemical composition of the magma, and the wavelength. As a proof of concept, we used our model on Kepler-10b to demonstrate the applicability of our approach. We present the spherical albedo values produced …