showing 36 of ~574560 from 574555 documents
Enterprise architecture operationalization and institutional pluralism: The case of the Norwegian Hospital sector
2021
Enterprise architecture (EA) is a systematic way of designing, planning, and implementing process and technology changes to address the complexity of information system (IS) landscapes. EA is operationalized when architecture visions move towards realization through concrete projects. We report a case study on the dynamics of operationalizing EA in the Norwegian hospital sector by exploring different EA project trajectories. Our empirical context is an institutionally pluralistic setting where multiple logics coexist. We show that the distinct logic of EA is added to the institutional context and we find that tensions among existing medical, technical, and managerial logics and EA principle…
Aircraft-based observation of meteoric material in lower-stratospheric aerosol particles between 15 and 68° N
2021
We analyse aerosol particle composition measurements from five research missions between 2014 and 2018 to assess the meridional extent of particles containing meteoric material in the upper troposphere and lower stratosphere (UTLS). Measurements from the Jungfraujoch mountaintop site and a low-altitude aircraft mission show that meteoric material is also present within middle- and lower-tropospheric aerosol but within only a very small proportion of particles. For both the UTLS campaigns and the lower- and mid-troposphere observations, the measurements were conducted with single-particle laser ablation mass spectrometers with bipolar-ion detection, which enabled us to measure the chemical c…
Investments in Latvia
2021
The effective attraction of investments to the national economy is a key factor, which provides favourable conditions to perform structural changes in the national economy, regional development as well as promotes technical progress. Therefore, investments in the public and the private sectors conduce development of the national economy and provide conditions to increase the overall competitiveness of a country. The purpose of research is to evaluate investment processes in Latvia before and after the global financial crisis, revealing investment-related problems. Also, to calculate the level of the desired investment, which would ensure the Latvia’s average GDP growth of 5% per year, accor…
Correlating the axial Zero Field Splitting with the slow magnetic relaxation in GdIII SIMs
2021
The field-induced out-of-phase magnetic response of a GdIII complex, selected by its good isolation in the network, has been analyzed and the behaviour of this quasi-isotropic cation has been related to its weak axial zero field splitting ∼0.1 cm-1.
Online Communication with Citizens. Should Latvian Public Institutions Learn from Foreign Experience?
2021
Civic engagement is a core value of democracy that approves legitimacy of democracy itself and decisions made by public institutions. In Latvia, civic engagement rates are decreasing, thus for public institutions it is important to find new ways how to engage citizens in the decision-making process. In the twenty-first century, it means that public institutions should also be present in social media. The objectives of the article are to identify foreign experience how public institutions are using social media for civic engagement and evaluate the reasons for Latvian public institutions to learn from this foreign experience. Accordingly, methods of the research are analysis of scientific pu…
Preaccelerator concepts for an energy-recovering superconducting accelerator
2021
In this paper we compare two concepts of a preaccelerator for the energy-recovery linac MESA: a hybrid injector that combines normal conducting and superconducting technology and a fully normal conducting injector. The particle source delivers polarized electrons at 100 keV. Thus the first accelerating section has to be of a graded-β kind. The graded-β section is designed with a final energy exceeding 1 MeV so TESLA-type nine-cell resonators can be used as superconducting cavities. The final energy of the preaccelerator shall be 5 MeV to avoid neutron production in the beam dump of the energy-recovery linac.
Importance of Webpage Content and Design for Higher Education Export
2021
Higher education export is gaining more and more importance taking into account international competition, the benefits offered by the industry and demographic changes in many countries – the number of local students is reducing due to low birth rates and extensive emigration of young people. There are many academic publications on several aspects related to higher education export. The aim of research is to analyse foreign students’ evaluation on the importance of different organisations’ (universities, agencies dealing with higher education export, ministries) webpage content and design for higher education export. Research methods used: scientific literature review analysis, evaluation o…
Student participation in peer interaction
2021
This study explores how students deal with material resources in their peer interaction when working in pairs in an open-ended problem-solving task. The productive use of material resources can be expected to support successful peer work. However, research into social phenomena in peer interaction is needed in order to identify and describe productive and less productive forms of dealing with material resources as students participate in open-ended problem-solving tasks. Consequently, this explorative study responds to this research need. Based on multimodal data, including video recordings, transcribed talk and the written contributions from four pairs of Year 7 students aged 12-13 years, …
false
2021
Introduction: Digital health technologies such as self-monitoring devices and apps are becoming increasingly important as tools to promote healthy habits and support individuals in their self-care. There is still a scarcity of research that builds on motivational theory to better understand the functioning of digital health technologies. The self-determination theory (SDT) is a macro theory of motivation that delineates three basic psychological needs that are linked to different types of motivation and lead to well-being when satisfied and illbeing when frustrated.Objective: To explore how the use of a digital tool for self-monitoring and communication with healthcare satisfies or frustrat…
One-Pot Oxidative C–H Activation/Aza-Prins-Type Reaction of Tertiary Alkynylamines: A Counter Ion-Induced Iminium Ion–Alkyne Cyclization
2021
Herein, the design and development of a new one-pot and metal-free oxidative C-H activation/aza-Prins type cyclization of alkynylamines is reported. The scope of this method was demonstrated by the preparation of ten new pyrido[2,1-a]isoquinolines in moderate to high yields (38-92%). Furthermore, a mechanistic proposal for the alkyne aza-Prins cyclization is described based on DFT calculations.
Long-term monitoring reveals topographical features and vegetation explain winter habitat use of an Arctic rodent
2021
AbstractCollapsing lemming cycles have been observed across the Arctic, presumably due to global warming creating less favorable winter conditions. The quality of wintering habitats, such as depth of snow cover, plays a key role in sustaining population dynamics of arctic lemmings. However, few studies so far investigated habitat use during the arctic winter. Here, we used a unique long-term time series to test whether lemmings are associated with topographical and vegetational habitat features for their winter refugi. We examined yearly numbers and distribution of 22,769 winter nests of the collared lemming Dicrostonyx groenlandicus from an ongoing long-term research on Traill Island, Nort…
Poesía, género y educación: de Mistral y Storni a Luque, Lanseros y Berbel
2021
espanolLa poesia escrita por mujeres en espanol no ha obtenido en el curriculum ni en los libros de texto de Secundaria el espacio que mereceria. Por ello en este trabajo presentamos una propuesta didactica para acercarla a los estudiantes de ultimo curso, que persigue, ademas, propiciar una fertil reflexion en torno a topicos de genero diversos, su formacion en calidad de lectores criticos, una iniciacion a la escritura creativa y una construccion reflexiva de sus identidades genericas. Previamente realizamos una breve introduccion teorica en la que analizamos los factores conducentes a la relegacion de la poesia en Secundaria, las practicas que se aconsejan y desaconsejan para una educaci…
Un intento de formación de élites criollas: La compañía de Caballeros Americanos de las Guaridas de Corps
2021
En este trabajo vamos a analizar una circunstancia ciertamente poco conocida, breve en el tiempo, pero que alcanza una especial relevancia: el establecimiento de una Compañía de Caballeros dentro del Real Cuerpo de Guardias de Corps. No es desconocido el carácter elitista de las guardias reales durante el siglo XVIII. La cercanía con el Rey podría significar un fulgurante ascenso dentro de la carrera militar o el acceso a relevantes puestos de carácter político. Con la denominación oficial de Segunda Compañía Española de Caballeros Americanos durante el reinado de Carlos IV se abrió la posibilidad de que los fieles vasallos de América, como se establece en el Real Decreto de constitución, p…
Impact of Regulatory Decisions of the Republic of Latvia on Sustainable Product Supply Provided by the Food Retail Chains
2021
This article reflects the impact of regulatory decisions of the Republic of Latvia on the food retail sector and sustainable product supply provided by food retail chains, as well as on operational trends. Attention has been drawn to the law of the Republic of Latvia on the key characteristics of foodstuffs and sales on the market. The research covers development of classification of the main instruments characterizing the products subject to the national regulation, as well as development of a scheme of the impact of the Latvian authorities on the operation of food retail chains. To implement the goal and tasks of the research, the authors have applied quantitative and qualitative research…
Victims and appeals at the International Criminal Court (ICC) : evaluation under international human rights standards
2021
Scholars have examined victim participation and reparations at the ICC. Nevertheless, no academic study focuses on victim participants and victims as parties (reparations claimants) in ICC appeals under international human rights law (IHRL) standards. This article seeks to: determine how victims’ roles as victim participants and parties (reparations claimants) take place in ICC appeals; and evaluate ICC’s law/practice on victims’ procedural roles/rights in appeals under IHRL. Victims at the ICC exercise procedural rights to: voice their views and concerns in appeals against final and interlocutory decisions (victim participants); and appeal reparations orders (parties). ICC’s law/practice o…
Classification par méthodes d’apprentissage supervisé et faiblement superviséd’images multimodales pour l’aide au diagnostic du lentigo malin en derm…
2021
Carried out in collaboration with the Saint-Étienne University Hospital, this work provides additional information to help the skin diagnosis by providing new decision methods on Lentigo Maligna and Lentigo Maligna Melanoma pathologies. To this end, the modalities regularly used in clinical conditions are made available to this work and are orchestrated within a multimodal process. Among image modalities, may be mentioned the clinical photography, the dermatoscopy, and the confocal reflectance microscopy. Initially, the first steps of this manuscript focus on reflectance confocal microscopy as the work in computer diagnostic assistance is relatively underdeveloped, in particular on the dete…
Structural Correspondence Between Organizational Theories
2021
AbstractOrganizational research constitutes a differentiated, complex and fragmented field with multiple contradicting and incommensurable theories that make fundamentally different claims about the social and organizational reality. In contrast to natural sciences, the progress in this field can’t be attributed to the principle of truthlikeness where theories compete against each other and only best theories survive and prove they are closer to the truth and thus demonstrate scientific knowledge accumulation. We defend the structural realist view on the nature of organizational theories in order to demonstrate that despite the multiplicity of isolated and competing explanations of organiza…
Applying Biomimicry to Cities: The Forest as Model for Urban Planning and Design
2021
International audience; The idea of applying biomimicry to cities is attracting increasing attention as a way of achieving sustainability. Undoubtedly the most frequently evoked natural model in this context is the forest, though it has not yet been investigated with any great scientific rigour. To overcome this lacuna, we provide: first, a justification of the model of the forest via what we call the arguments from “fittingness”, “scale”, and “complexity”; second, an exploration of various key innovations made possible by this model in the fields of urban planning, urban water systems, urban energy and transport systems, and urban food and nutrient systems.
rac-11-Selena-12,13-diazabicyclo[10.3.0]pentadeca-10a(13a),12-dien-1-ol
2021
The title compound, C12H20N2OSe, crystallizes in strands of enantiomeric molecules connected via O—H...N hydrogen bonds. There are only slight deviations from an ideal gauche conformation in the decamethylene chain, indicating just a little strain.
The design of magneto-plasmonic nanostructures formed by magnetic Prussian Blue-type nanocrystals decorated with Au nanoparticles.
2021
Abstract: We have developed a general protocol for the preparation of hybrid nanostructures formed by nanoparticles (NPs) of molecule-based magnets based on Prussian Blue Analogues (PBAs) decorated with plasmonic Au NPs of different shapes. By adjusting the pH, Au NPs can be attached preferentially along the edges of the PBA or randomly on the surface. The protocol allows tuning the plasmonic properties of the hybrids in the whole visible spectrum.
Innovation efficiency: a bibliometric review and future research agenda
2021
Innovation efficiency has become a phenomenon of global interest. This paper reviews 165 articles from academic journals of innovation efficiency, applies the data-driven text mining approach to ma...
RNN- and LSTM-Based Soft Sensors Transferability for an Industrial Process
2021
The design and application of Soft Sensors (SSs) in the process industry is a growing research field, which needs to mediate problems of model accuracy with data availability and computational complexity. Black-box machine learning (ML) methods are often used as an efficient tool to implement SSs. Many efforts are, however, required to properly select input variables, model class, model order and the needed hyperparameters. The aim of this work was to investigate the possibility to transfer the knowledge acquired in the design of a SS for a given process to a similar one. This has been approached as a transfer learning problem from a source to a target domain. The implementation of a transf…
L’éducation à la santé : de quoi parle-t-on ?
2021
International audience
Exercise intensity and markers of inflammation during and after (neo-) adjuvant cancer treatment.
2021
Exercise training has been hypothesized to lower the inflammatory burden for patients with cancer, but the role of exercise intensity is unknown. To this end, we compared the effects of high-intensity (HI) and low-to-moderate intensity (LMI) exercise on markers of inflammation in patients with curable breast, prostate and colorectal cancer undergoing primary adjuvant cancer treatment in a secondary analysis of the Phys-Can randomized trial (NCT02473003). Sub-group analyses focused on patients with breast cancer undergoing chemotherapy. Patients performed 6 months of combined aerobic and resistance exercise on either HI or LMI during and after primary adjuvant cancer treatment. Plasma taken …
The Human Leukocyte Antigen-DPB1 Degree of Compatibility Is Determined by Its Expression Level and Mismatch Permissiveness: A German Multicenter Anal…
2021
T-cell epitope matching according to the TCE3 algorithm classifies HLA-DPB1 mismatches in permissive and non-permissive. This classification has been shown to be predictive for mortality and acute GvHD (aGvHD) events in large international cohorts. We retrospectively genotyped HLA-DPB1 in 3523 patients transplanted in Germany between 2000 and 2014 and in their unrelated donors using an Illumina amplicon-NGS based assay. Aim of the study was to evaluate DP-compatibility beyond the established TCE3 algorithm by assessing the combined effect of several DP-mismatch parameters on post-transplant outcome. We implemented an extended DP-mismatch assessment model where TCE3, DP allotype expression w…
Recombinant FVIII Products (Turoctocog Alfa and Turoctocog Alfa Pegol) Stable Up to 40°C
2021
Mariasanta Napolitano,1 Arne Agerlin Olsen,2 Anne Mette Nøhr,2 Hermann Eichler3 1Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo Reference Regional Center for Thrombosis and Hemostasis, Hematology Unit, Palermo, Italy; 2Novo Nordisk A/S, Biopharm Manufacturing Development, Gentofte, Denmark; 3Saarland University and Saarland University Hospital, Institute of Clinical Haemostaseology and Transfusion Medicine, Homburg (Saar), GermanyCorrespondence: Anne Mette NøhrBiopharm Manufacturing Development, Novo Nordisk A/S, Nybrovej 80, Gentofte 2820, DenmarkTel +45 3075 1619Email amnq@novonordisk.…
Neuroendocrine differentiation in a large series of genetically-confirmed Ewing’s sarcoma family tumor: Does it provide any diagnostic or prognostic …
2021
Given the potential for neuroendocrine differentiation in Ewing's sarcoma family of tumors (ESFT), we aimed to determine neuroendocrine expression in a large series of genetically-confirmed ESFT and its prognostic significance in clinically-localised neoplasms (n = 176). Slides prepared from tissue microarrays were stained for Insulinoma-associated protein 1 (INSM1), CD56, chromogranin-A and synaptophysin. INSM1 expression was present in 59% of ESFT, while synaptophysin, chromogranin-A and CD56 were expressed in only 13%, 8% and 5% of ESFT, respectively. Histological subtypes were only significantly correlated with INSM1 (p = 0.032) or CD56 (p = 0.016) immunoexpression. Regarding prognosis,…
Health-related quality of life in European childhood cancer survivors: Protocol for a study within PanCareLIFE
2021
Background Survival after childhood cancer has improved to more than 80% during the last few years, leading to an increased number of childhood cancer survivors. Cancer itself, or its treatment, may cause chronic health conditions, including somatic and mental sequelae, which may affect survivors’ health-related quality of life (HRQoL). Objective The project PanCareLIFE aims to establish a large database with comprehensive data on childhood cancer survivors from different European countries, including data on HRQoL. Within PanCareLIFE, this study aims to describe HRQoL in survivors, investigate predictors of HRQoL, and describe the association of HRQoL with hearing and female fertility imp…
Représentation du bien-être, sa caractérisation et son implication dans l'alimentation
2021
International audience
Nanocatalysts for High Selectivity Enyne Cyclization: Oxidative Surface Reorganization of Gold Sub-2-nm Nanoparticle Networks
2021
International audience; Ultrasmall gold nanoparticles (NPs) stabilized in networks by polymantane ligands (diamondoids) were successfully used as precatalysts for highly selective heterogeneous gold-catalyzed dimethyl allyl(propargyl)malonate cyclization to 5-membered conjugated diene. Such reaction usually suffers from selectivity issues with homogeneous catalysts. This control over selectivity further opened the way to one-pot cascade reaction, as illustrated by the 1,6-enyne cycloisomerization–Diels–Alder reaction of dimethyl allyl propargyl malonate with maleic anhydride. The ability to assemble nanoparticles with controllable sizes and shapes within networks concerns research in sensor…
Retinal Vascular Assessment in Psoriasis: A Multicenter Study
2021
PurposeTo investigate the vascular status of the macula in psoriasis patients without history of ocular inflammation by Optical Coherence Tomography Angiography (OCTA).MethodsThis prospective cross-sectional multicenter study included 55 psoriasis patients and 55 control healthy subjects. A complete eye examination and 6 mm × 6 mm OCTA imaging were performed. Retinal vascular status was evaluated by analyzing vascular density (VD) of superficial vascular plexus (superficial wVD) and deep vascular plexuses (deep wVD) in a 6 mm × 6 mm area and in foveal (superficial fVD and deep fVD) and parafoveal sectors (superficial pVD and deep pVD). In addition, foveal thickness (FT) and foveal avascular…
Effectiveness of a screening program for HBV, HCV, and HIV infections in African migrants to Sicily
2021
BACKGROUND Migrants from Africa are vulnerable to viral infections during their journey. METHODS Migrants who arrived in western Sicily were offered early screening for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection. A questionnaire was administered to evaluate risk factors, and antiviral therapy was offered to subjects with active infection. A multiple regression analysis and adjusted odds ratio were obtained to evaluate risk factors. RESULTS Overall, 2,639 of 2,751 (95.9%) migrants who arrived between 2015 and 2017 accepted screening and 1,911 (72.4%) completed the questionnaire. HBsAg was positive in 257 (9.7%) migrants, 24 (0.9%) were …
Sustainability: Economic, Environmental and Public Issues. Marketing Possibilities
2021
The research aims to update the corporate marketing role in promoting sustainability. The study is based on the assessment of today’s economic, ecological, and social responsibility issues, as well as public issues associated with the development of sustainability. The following scientific research methods have been applied in the research: analytical, comparing, graphical, statistical and surveillance methods. The authors have studied sustainability issues, i.e., economic, environmental and social, in the world and particularly in Latvia, as well as their impact on public welfare. In research, there was chosen and analysed the Latvian food retail industry, which makes a significant contrib…
An Optical Classification Tool for Global Lake Waters
2021
Shallow and deep lakes receive and recycle organic and inorganic substances from within the confines of these lakes, their watershed and beyond. Hence, a large range in absorption and scattering and extreme differences in optical variability can be found between and within global lakes. This poses a challenge for atmospheric correction and bio-optical algorithms applied to optical remote sensing for water quality monitoring applications. To optimize these applications for the wide variety of lake optical conditions, we adapted a spectral classification scheme based on the concept of optical water types. The optical water types were defined through a cluster analysis of in situ hyperspectral…
Evolutionary psychology in marketing: Deep, debated, but fancier with fieldwork
2021
Evolution of a Non-Hermitian Quantum Single-Molecule Junction at Constant Temperature
2021
This work concerns the theoretical description of the quantum dynamics of molecular junctions with thermal fluctuations and probability losses. To this end, we propose a theory for describing non-Hermitian quantum systems embedded in constant-temperature environments. Along the lines discussed in [A. Sergi et al., Symmetry 10 518 (2018)], we adopt the operator-valued Wigner formulation of quantum mechanics (wherein the density matrix depends on the points of the Wigner phase space associated to the system) and derive a non-linear equation of motion. Moreover, we introduce a model for a non-Hermitian quantum single-molecule junction (nHQSMJ). In this model the leads are mapped to a tunneling…