showing 36 of ~574560 from 574555 documents
Assessment of Pulmonary Mechanics and Gastric Inflation Pressure During Mask Ventilation
1995
AbstractIntroduction:Mask ventilation is a procedure routinely used in emergency medicine. Potential hazards are inadequate alveolar ventilation and inflation of the stomach with air, leading to subsequent regurgitation and aspiration. The aim of this study was to measure lung function and gastric inflation pressures during mask ventilation.Methods:For this purpose, 31 patients scheduled for routine urological procedures were studied during induction of anesthesia. Lung function was assessed by recording respiratory flow and pressure directly at the face mask. Gastric inflation was observed with a microphone taped to the epigastric area.Results:Gastric inflation occurred in 22 of the 31 pat…
Shift and scale-invariant correlator using a radially stretched phase-only filter
1995
A radial stretching of the phase only filter depending on the energy angular distribution of the target spectrum is used to perform shift and scale invariant pattern recognition. The complex conjugate of a basic size target Fourier transform and the cumulative energy angular distribution are calculated. Then the radially stretched filter providing the same energy contribution to the correlation peak independent on the target size is prepared and used in a conventional correlator, with spherical-wave illumination. The maximum scale ratio of recognizable objects equals 1:1.5. Computer simulations and experimental results, showing the performance of the filter are presented.
Beyond the standard model with effective lagrangians
1995
We discuss some applications of the effective quantum field theory to the description of the physics beyond the Standard Model. We consider two different examples. In the first one we derive, at the one-loop level, an effective lagrangian for an extension of the Standard Model with a charged scalar singlet by ``integrating out'' the heavy scalar. In the second example we illustrate the use of general effective theories at the loop level.
La protéine intrinsèque bobTIP106 appartient à un complexe multimérique du tonoplaste de Brassica oleracea var. Botrytis L.
1995
Diagnosis of Endometrial Carcinoma: Predictive Value of Transvaginal Color Doppler
1995
The objective of this study was to determine whether transvaginal ultrasound plus color Doppler flow improve the ability to diagnose endometrial carcinoma and allow better discrimination between benign and malignant endometrial lesions. One hundred thirty women with abnormal uterine bleeding were evaluated with transvaginal color Doppler before fractional dilatation and curettage (D&C). The endometrial line thickness and endometrial characteristics were evaluated by endosonography. The resistive and pulsatile indices of the uterine arteries and of the endometrium were evaluated with transvaginal color Doppler. Following D&C and tissue diagnosis, women were divided into two groups, 62 with a…
Cardiomyopathic lentiginosis: an echo-Doppler report
1995
We report a case of a 64-year-old woman with cardiomyopathic lentiginosis. All the echocardiographic features of a hypertrophic obstructive cardiomyopathy were detected, with an accurate noninvasive measure of the left ventricle outflow gradient.
Non-decoupling of Heavy Neutrinos and Lepton Flavour Violation
1995
We consider a class of models predicting new heavy neutral fermionic states, whose mixing with the light neutrinos can be naturally significant and produce observable effects below the threshold for their production. We update the indirect limits on the flavour non-diagonal mixing parameters that can be derived from unitarity, and show that significant rates are in general expected for one-loop-induced rare processes due to the exchange of virtual heavy neutrinos, involving the violation of the muon and electron lepton numbers. In particular, the amplitudes for $\mu$--$e$ conversion in nuclei and for $\mu\to ee^+e^-$ show a non-decoupling quadratic dependence on the heavy neutrino mass $M$,…
Apigenin and tangeretin enhance gap junctional intercellular communication in rat liver epithelial cells
1995
National audience
Cloning and expression of a cDNA copy of the viral K28 killer toxin gene in yeast
1995
The killer toxin K28, secreted by certain killer strains of the yeast Saccharomyces cerevisiae is genetically encoded by a 1.9 kb double-stranded RNA, M-dsRNA (M28), that is present within the cell as a cytoplasmically inherited virus-like particle (VLP). For stable maintenance and replication, M28-VLPs depend on a second dsRNA virus (LA), which has been shown to encode the major capsid protein (cap) and a capsid-polymerase fusion protein (cap-pol) that provides the toxin-coding M-satellites with their transcription and replicase functions. K28 toxin-coding M28-VLPs were isolated, purified and used in vitro for the synthesis of the single-stranded M28 transcript, which was shown to be of pl…
Malignantly transformed non-parenchymal liver epithelial cells and transformed oval cells suppress the homotypical gap junctional intercellular commu…
1995
Isolated rat liver parenchymal cells (PC) were co-cultured with a non-parenchymal rat liver epithelial cell line (NEC) or with an oval cell line. The homotypical gap junctional intercellular communication (GJIC) between the liver PC was measured after microinjection of Lucifer Yellow by dye transfer. The rat liver PC were dye coupled between 87% and 100% for at least 1 week in both co-cultures, in contrast to PC In monoculture between which no dye coupling was left after 1 week. When liver PC were co-cultured with a transformed and tumorigenic NEC or with a transformed and tumorigenic oval cell line the homotypical GJIC between the liver PC was drastically decreased with culture time, and t…
Converging paths to Notes
1995
The nature of the information systems needed in a networked firm is not well known: nor is the process leading to particular solutions. Describes a small computer‐consulting company which works as a network of independent consultants, and analyses the slow and circuitous path from recognizing its IS/IT needs to its commitment to a particular solution as seven steps; using ideas of structuration theory as a focus. During the selection process, participants formed new interpretations of the firm, of technology, and of the appropriate process towards a feasible solution. New resources – both material and symbolic – were acquired to enable the search. Existing “norms” provided boundaries for th…
Synthesis of chlorinated alkylbibenzyls and 9-chlororetene
1995
Abstract The synthesis of chlorinated alkylbibenzyls and 9-chlororetene is described. These compounds were synthesized for use as model compounds in analytical and toxicological characterization. The structures of the synthesized model compounds found to be very similar to those identified in pulp mill effluent and products. The 1H NMR and mass spectral data for the compounds are also reported.
DNA Amplification Fingerprinting for Subtyping Neisseria gonorrhoeae Strains
1995
Background and Objectives DNA amplification fingerprinting is used in most epidemiologic studies as a substitute for conventional typing methods. DNA amplification fingerprinting and conventional typing methods were compared in this epidemiologic study of Neisseria gonorrhoeae. Goal of This Study To differentiate 70 Neisseria gonorrhoeae isolates from untreated patients with urogenital gonococcal infection. Study Design Gonococcal strains were characterized by auxo-typing, serotyping, plasmid profile, antibiotic sensitivity, and DNA amplification fingerprinting. The method of unweighted pair-group average linkage was used for cluster analysis. Discriminatory power was calculated applying Si…
DNA single strand break analysis in mononuclear blood cells of petrol pump attendants
1995
DNA single strand breaks, including DNA adducts that lead to alkali-labile sites, were measured in peripheral mononuclear blood cells of 35 petrol pump attendants by alkaline filter elution. Blood samples from petrol pump attendants were taken on Monday and Friday. Additionally, DNA single strand breaks of smoking and non-smoking control persons were examined. For the smoking (n = 12) and the non-smoking controls (n = 20) a mean normalized elution rate of 1.49 +/- 0.52 (mean value +/- 95% confidence interval) and 1.32 +/- 0.28, respectively, was obtained. The difference between smoking and non-smoking controls was not statistically significant (U test). An increase in DNA single strand brea…
Recent Changes in Student Life and Study ProcessesABSTRACT
1995
This research on university and university students was carried out during the 1980s at the University of Jyvaskyla in Finland. It is argued that the student years no longer constitute a ‘classically’ academic life stage; instead, the modem student's life is divided between study and part‐time employment. The uncertain economic situation and social immaturity of today's students hampers their identity formation. Student culture has lost its independence and vitality, and the basic structures of students’ life‐world have fragmented so that their lives no longer revolve around the university. Moreover, curricularization in universities has instrumentalized the study process and the relation o…
The new world of human genetic technologies: The policy environment and impacts of genetic screening tests
1995
Today it is possible to screen for mutated DNA sequences which do not induce any diseases but predispose to develop diseases under certain environmental condition. These latter disorders are called “multifactorial” since they result from the interplay of genetic and environmental factors. Among multifactorial disorders there are job-related diseases whose genetic component can be identified by genetic screening tests. The use of these tests to predict occupational disorders, to cut down on them, and to save costs—in particular for absenteeism, health care, and lawsuits—is of interest to employers and insurers. As for employees, it could entail an extremely deep invasion of privacy, economic…
Changes in microregional perfusion, oxygenation, ATP and lactate distribution in subcutaneous rat tumours upon water-filtered IR-A hyperthermia
1995
The effect of hyperthermia on microcirculatory and metabolic parameters in s.c. DS-sarcomas of different sizes on the hind foot dorsum of SD-rats was investigated. Hyperthermia was carried out using a novel water-filtered, infrared-A radiation technique. Heating was performed at a rate of 0.5 degrees C/min until 44 degrees C was achieved in the tumour centre, which was maintained for 60 min. Using a multichannel laser Doppler flowmeter, red blood cell flux could be assessed continuously and at several sites within the tumour tissue simultaneously. Substantial inter-site variations in laser Doppler flux (LDF) were observed during hyperthermia which were independent of tumour size, site of me…
Autonomic dysfunction in patients with achalasia.
1995
It has been previously shown that patients with achalasia may have motor abnormalities of the stomach, small bowel and biliary system. This study investigates whether a disturbance of extraintestinal autonomic function occurs. Autonomic function studies were performed in 15 patients with achalasia and 15 age- and sex-matched healthy controls. Pupillo-grams were obtained during darkness, light exposure and after pilocarpine administration. Cardiovascular function studies included determinations of heart rate variation during deep breathing and orthostasis. In addition, we determined blood pressure changes in response to sustained handgrip, cold exposure and orthostasis. Neurohormonal functio…
Evidence that water transmits Vibrio vulnificus biotype 2 infections to eels
1995
Vibrio vulnificus biotype 2 is classically considered an obligate eel pathogen. However, it has recently been associated with one human septicemic case. In this paper, the opportunistic behavior of this pathogen is discussed. The bacterium can survive alone in brackish water or attached to eel surfaces for at least 14 days. It is able to spread through water and infect healthy eels by using skin as a portal of entry. These results suggest that water and infected eels may act as reservoirs of infection. A capsule seems to be essential for waterborne infectivity, which would explain why cells recovered from naturally diseased eels give rise to pure cultures of opaque colonies. The spread of t…
Structure function as a tool in AE and Dst time series analysis
1995
A new method to analyse the structure function (SF) has been constructed and used in the analysis of the AE time series for the years 1978-85 and Dst time series for 1957-84. It is shown that this SF analysis makes a clear distinction between affine and periodicity dominated time series, and it displays the essential periodicities of the series in a range relevant to its characteristic time scale. The AE time series is found to be affine such that the scaling exponent changes at a time scale of 113 (±9) minutes. On the other hand, in the SF function analysis, the Dst data are dominated by the 24-hour and 27-day periods. The 27-day period is modulated by the annual variation.
Early-onset ataxia with cardiomyopathy and retained tendon reflexes maps to the friedreich's ataxia locus on chromosome 9q
1995
Absence of lower limb tendon reflexes has been considered an essential diagnostic criterion for Friedreich's ataxia (FA). However, preservation of knee and ankle jerks has been reported in a few patients. Linkage analysis to FA locus (FRDA) on chromosome 9q13-21.1 was performed in 11 patients from 6 families with FA phenotype, including cardiomyopathy, but retained reflexes (FARR). A maximal lod score of 3.38 at recombination fraction theta equal to 0.00 was obtained demonstrating that FARR maps to the FRDA locus. These results suggest that FARR is a variant phenotype of FA.
1H, 13C and 17O NMR spectral study of chlorinated 3,4-dihydroxybenzaldehydes (protocatechualdehydes)
1995
Abstract Chlorinated 3,4-dihydroxybenzaldehydes have been studied by means of 1 H, 13 C and 17 O NMR spectroscopy. The 1 H and 13 C NMR spectral assignments are based on 2-dimensional 13 C- 1 H chemical shift correlation spectroscopy (COSY). The 17 O NMR measurements at natural isotope content in organic solvents are problematic owing to the poor solubility of the compounds and/or broadness of the resonance lines. In aqueous alkaline solutions, however, all protocatechualdehydes exhibit “easy-to-detect” 17 O NMR spectral characteristics. The 17 O NMR chemical shifts in the range of 140–480 p.p.m. are interpreted as arising from the different canonical structures of formyl substituted phenol…
Impairment of intracellular antiviral defense with age: age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2…
1995
The 2',5'-oligoadenylate (2-5A) system is involved in the defense of mammalian cells against virus infection. In a previous study [25], we demonstrated that the activities of the enzymes which synthesize and degrade 2-5A [2-5A synthetase (2-5OAS) and 2',3'-exoribonuclease] and of the enzyme that is activated by 2-5A (ribonuclease L) change during aging and development in different tissues of rat. The age-dependent decrease in 2-5OAS activity and increase in 2-5A nuclease activity results in a decrease in the cellular 2-5A content, suggesting that the efficiency of the antiviral 2-5A system is impaired in aged rats. Here we determined the age-dependent changes in the level of mRNA coding for…
Interaction Diagram of a Circular Bar in Torsion and Extension
1995
For a circular bar of perfectly plastic material and subjected to a cyclically variable torque and a constant axial force, the interaction (or generalized Bree) diagram is derived by a direct method in which Melan’s theorem is used to locate the nonratchetting load boundary.
Prenatal diagnosis of infantile neuronal ceroid-lipofuscinosis: a combined electron microscopic and molecular genetic approach.
1995
Based on two unrelated index patients afflicted with INCL, fetal chorion tissues were studied from subsequent pregnancies of the two respective mothers resulting in the prenatal diagnosis of INCL in two of the three pregnancies. Documentation of INCL was based on electron microscopy and DNA studies of the biopsied chorion tissue, later confirmed in the two affected fetuses after termination of their pregnancies by demonstrating INCL-specific lipopigments in post-mortem tissues, in the liver of both aborted fetuses and, additionally, in spleen and skeletal muscle of one of the affected fetuses. The autolysis of the aborted tissues, however, precluded a systematic documentation of all affecte…
On the thermodynamic treatment of poly(vinylidene fluoride)/polystyrene blend under liquid—liquid phase separation conditions
1995
Abstract This paper deals with experimental and theoretical investigations on the compatibility of binary of polymer blends in solution. The experimental phase boundary of a crystalline polymer such as poly(vinylidene fluoride) with polystyrene (an amorphous polymer) in dimethylformamide as solvent has been determined by size-exclusion chromatography at 25°C. The composition of the coexisting phases has been used to calculate interaction parameters by means of the Flory—Huggins-type function for the free energy of mixing, including composition dependence of the polymer-polymer interaction parameter and a first correction term denoted as ternary interaction parameter. The calculation of thes…
Benzimidazolones and renzapride facilitate acetylcholine release from guinea-pig myenteric plexus via 5-HT4 receptors
1995
The effects of the 5-HT4 receptor agonists BIMU 8, BIMU 1, renzapride and of the 5-HT1p receptor agonist 5-hydroxyindalpine on basal and electrically evoked outflow of tritium were studied in guinea-pig longitudinal muscle myenteric plexus preparations preincubated with [3H]choline. Muscle contractions were recorded simultaneously. BIMU 8 caused a calcium dependent and tetrodotoxin sensitive increase in basal [3H]outflow that was assumed to represent release of [3H]acetylcholine. In addition, BIMU 8 enhanced the release of [3H]acetylcholine and twitch contractions evoked by submaximal electrical stimulation. Ondansetron (1 μmol/l) did not change the effects of BIMU 8, but DAU 6285 and tropi…
Level scheme ofZr101and structure of theN=61 Sr, Zr, and Mo isotones
1995
The neutron-rich nucleus $_{40}^{101}\mathrm{Zr}_{61}$ has been studied at the isotope separator ISOLDE via the \ensuremath{\beta} decay of $^{101}\mathrm{Y}$. A detailed level scheme has been obtained from \ensuremath{\gamma}-ray singles, \ensuremath{\gamma}-\ensuremath{\gamma}-t and \ensuremath{\beta}-\ensuremath{\gamma}-t coincidence measurements. The level structure of $^{101}\mathrm{Zr}$ is similar to that of its isotone $^{103}\mathrm{Mo}$ showing that, in contrast to their Sr neighbors, the Zr isotopes do not reach maximum of deformation immediately at its onset. This result is rather well reproduced by particle-rotor coupling calculations. A level systematics for the deformed N=61 i…
Search for CP violation in the decay Z → τ+τ−
1995
Data collected by ALEPH in the years 1990, 1991 and 1992 have been used to update a previous search for CP violation in the decay of the Z into tau(+)tau(-). The measurement of the weak dipole form factor of the tau lepton has been performed by studying correlations between the tau leptons. No signal of CP violation was found. The weak dipole form factor is found to be ($) over tilde d(tau) = (+0.15 +/- 0.58(stat) +/- 0.38(sys)) 10(-17)e . cm, obtained with 19628 identified tau(+)tau(-) events. This gives an upper limit on the weak dipole form factor of j\($) over tilde d(tau)\ < 1.5 . 10(-17)e . cm at the 95% confidence level.
EXACT SOLUTIONS FOR A CLASS OF FRACTAL TIME RANDOM WALKS
1995
Fractal time random walks with generalized Mittag-Leffler functions as waiting time densities are studied. This class of fractal time processes is characterized by a dynamical critical exponent 0<ω≤1, and is equivalently described by a fractional master equation with time derivative of noninteger order ω. Exact Greens functions corresponding to fractional diffusion are obtained using Mellin transform techniques. The Greens functions are expressible in terms of general H-functions. For ω<1 they are singular at the origin and exhibit a stretched Gaussian form at infinity. Changing the order ω interpolates smoothly between ordinary diffusion ω=1 and completely localized behavior in the …
Experimental studies of the rheological behavior of a demixing biopolymeric sol
1995
Experimental data are presented concerning a large transient viscosity surge occurring in the course of spinodal demixing of agarose aqueous solutions. The study includes the effects of water perturbation by minor proportions of compatible cosolutes. Three observations are noteworthy. One concerns an upward or downward shift of the spinodal temperature, caused by cosolutes, which agrees with their expected modulation of solvent-induced forces. The second concerns the time of appearance of the viscosity surge. This is observed to follow a critical law, with an exponent independent of polymer concentration and solvent perturbation. The third concerns the inverse-power-law dependence of the vi…
Quadrupole excitation of stored ion motion at the true cyclotron frequency
1995
Abstract The motion of an ion in a Penning trap has been investigated in the presence of an azimuthal quadrupole radio frequency field and a damping force provided by buffer gas collisions. Analytical expressions are derived which describe the line shape of the cyclotron resonance as well as the properties of the mass-selective cooling mechanism for heavy ions. Excellent agreement is observed between theoretical results and experimental data obtained with the tandem Penning trap mass spectromer ISOLTRAP at ISOLDE (CERN).
Does transvaginal color Doppler sonography differentiate between developing and involuting ectopic pregnancies?
1995
The objective of this study was to assess the addition of transvaginal color Doppler imaging to transvaginal ultrasonography and beta-human chorionic gonadotropin values to differentiate between developin and involuting ectopic pregnancies. Forty surgically confirmed ectopic pregnancies were classified into developing or involuting according to histopathologic findings. Results were compared retrospectively with the plasma beta-human chorionic gonadotropin values as well as the resistive index and pulsatility index obtained in corpora lutea and peritrophoblastic flow in serial examinations. Student's t-test was used for comparison of means. Logistic regression analysis was applied to predic…
Respiratory epithelium exposed to sulfur dioxide--functional and ultrastructural alterations.
1995
The value of morphological investigations of airway mucosa should be compared to a functional method when estimating the toxicity of airborne pollutants. In 34 guinea pig tracheas, mucociliary activity was measured using a modified light beam reflex method before and following exposure to sulfur dioxide for 30 minutes in concentrations ranging between 7.5 and 37.5 mg/m3. Exposure to air served as a control. Simultaneously, specimens were taken for light and electron microscopy. Mucociliary activity decreased from 8.4 +/- 2.9 Hz (control exposure) to 4.0 +/- 2.9 Hz following exposure to 7.5 mg/m3, to 3.4 +/- 2.7 Hz at 15 mg/m3 sulfur dioxide, to 1.8 +/- 2.2 Hz at 22.5 mg/m3 sulfur dioxide, t…
Concentration and energy fluctuations in a critical polymer mixture
1995
A semi-grand-canonical Monte Carlo algorithm is employed in conjunction with the bond fluctuation model to investigate the critical properties of an asymmetric binary (AB) polymer mixture. By applying the equal peak-weight criterion to the concentration distribution, the coexistence curve separating the A-rich and B-rich phases is identified as a function of temperature and chemical potential. To locate the critical point of the model, the cumulant intersection method is used. The accuracy of this approach for determining the critical parameters of fluids is assessed. Attention is then focused on the joint distribution function of the critical concentration and energy, which is analysed usi…
Distortion product otoacoustic emissions in healthy newborns: normative data.
1995
Distortion product otoacoustic emissions (DPOAE) offer an alternative to transiently evoked otoacoustic emissions (TEOAE) as an audiological test. The former can be used as a screening technique, and may also provide frequency-specific information about the functional state of the cochlea. We recorded DPOAE in a group of healthy newborns to establish the Characteristics of a DPOAE “audiogram” (DP-gram) in this population. The DP-gram can be obtained with characteristics quite similar to those observed in adults, with two sharp peaks of maximum amplitude at F2 frequencies of 2 kHz and 5-6 kHz, and a decline in DPOAE amplitude in mid frequencies. The results confirm the limitations of DPOAE r…