showing 36 of ~574560 from 574555 documents
Structural cuticular proteins in termite queens
1978
0305-0491 (Print) Journal Article; The abdominal cuticle from queens of two termite species, Cubitermes fungifaber and Macrotermes bellicosus, has been investigated with respect to changes occurring during development of physogastry. The following properties have been determined: 1. Relative content of protein and chitin and the percentage of easily extracted protein. 2. Number of proteins separated by electrophoresis and their molecular weights. 3. Amino acid compositions of the intertergal and pleural membranes and of the neosclerites in M. bellicosus. The intertergal and pleural membranes appear to be typical "soft" cuticles, and the neosclerites must also be considered "soft" cuticles, …
Virazole (Ribavirin) a Cytostatic Agent
1978
Virazole (1-β-D-ribofuranosyl-1,2,4-triazole-3carboxamide,ribavirin) is a synthetic triazol nucleoside with a broad spectrum of antiviral activity. But virazole affects the metabolism not only of virus infected cells. Virazole strongly inhibits the cell proliferation of mouse lymphoma cells (L 5178y), which were not infected with DNA- or RNA-viruses. Starting with 3 × 103 cells/ml and an incubation period of 72 hr, the drug reduces the cell proliferation to 50% (= ED50 concentration) in a concentration of 4,7 μM.
INTERACTION BETWEEN NORADRENALINE AND DOPAMINE IN THE ISOLATED GUINEA-PIGATRIA
1978
Espagne. Le processus de démocratisation en Espagne.
1978
La dependencia de las categorías conceptuales en las ciencias sociales
1978
Some decision results for recognizable sets in arbitrary monoids
1978
Linguistic and Cultural Unity and Diversity in Spanish Education
1978
(1978). Linguistic and Cultural Unity and Diversity in Spanish Education. Compare: A Journal of Comparative and International Education: Vol. 8, No. 1, pp. 101-111.
Las colectividades campesinas durante la Guerra Civil española: Villamalea (1936-39)
1978
Las colectividades campesinas durante la Guerra Civil española: Villamalea (1936-39) recoge la historia de las colectividades de CNT y UGT en la localidad.
GIL OLCINA,ANTONIO. La propiedad señorial en tierras valencianas. Valencia, Del Cenia al Segura, 1979 [Ressenya]
1978
Dos mutaciones paisajísticas ligadas al arrozal en la antigua gobernación de San Felipe (Xátiva)
1978
La Torre de Foios (Llucena, Castelló): Elementos para su cronología
1978
Dihydrodiol Dehydrogenase: An Important Enzyme in Dihydrodiol-Epoxide Pathway — Mediated Benzo(A)Pyrene Mutagenicity
1978
Benzo(a)pyrene is metabolized to two major groups of mutagenically reactive metabolites: Monofunctional epoxides and dihydrodiol-epoxides. Various monooxygenase forms catalyze the various pathways at very different rates. In metabolic situations where the contribution by dihydrodiol-epoxides is small, epoxide hydratase represents a very efficient protective system. However, in situations where the mutagenic effect is predominately due to dihydrodiol-epoxide, the effect of epoxide hydratase is complicated and weak. We have now obtained evidence that a dihydrodiol dehydrogenase represents an efficient protective system in the latter situation. The enyzme was purified to homogeneity and the pu…
Complexes of organometallic compounds. XLIX. A Mössbauer-zeeman spectroscopic study of glycylglycinato-O,N,N(2−) diphenyltin(IV), and the point-charg…
1978
ACTION POTENTIAL, MEMBRANE CURRENTS AND FORCE OF CONTRACTION IN MAMMALIAN HEART MUSCLE FIBRES TREATED WITH QUINIDINE
1978
The effects of quinidine on electrical and mechanical activity were investigated in atrial and/or ventricular heart muscle preparations from guinea pigs and cats. Quinidine (1--100 micrometer) exerted negative inotropic effects in papillary muscles from guinea pigs and cats. In guinea-pig left atria, a positive inotropic effect was superimposed on the negative inotropic effect in response to quinidine. Quinidine (100 micrometer) prolonged the duration of the action potential in guinea-pig atria but shortened it in guinea-pig ventricular muscle. In cat papillary muscles, the late repolarization was markedly prolonged by quinidine, but virtually no change of the plateau phase was observed. Th…
A Universal and Sensitive Method for Gas Chromatographic Determination of Volatile Substrates and Metabolites
1978
The concentration of solutes from aqueous solutions in the μl range is still a problem in gas chromatographic trace analysis (e.g. J.S. Fritz, Acc. Chem. Res. 10, 67, 1977).
Note sur un ensemble de fibules inachevées de Bibracte (Mont-Beuvray)
1978
International audience
Muscarinic Modulation of Acetylcholine Release from the Myenteric Plexus of the Guinea Pig Small Intestine
1978
The concept of a local feedback regulation of neurotransmitter release has been most intensively studied in the adrenergic system (See Ref. 13 for review). The feedback hypothesis of noradrenaline release is based on the findings that α-adrenolytic drugs enhance, and α-adrenoceptor agonists reduce neuronal noradrenaline release. Relatively few systematic studies have been made on the influence of cholinolytic and cholinomimetic drugs on the release of ACh. Szerb and Somogyi (14) reported that the potent muscarinic agonist oxotremorine inhibited ACh output from cerebral cortical slices. Further, the muscarinic antagonists atropine and hyoscine have been found to facilitate the release of ACh…
Aktywność kompleksów katalitycznych wytworzonych z ortotytanianów izopropylowych i seskwietylochloroglinu w procesie polimeryzacji etylenu
1978
Zbadano aktywność katalityczną w procesie polimeryzacji etylenu czterech kompleksów otrzymanych z seskwietylochloroglinu i związków tytanowych typu (i-C3H7O)4-nTiCln (gdzie n=0-3). Dobrano warunki tworzenia kompleksu aktywnego i parametry polimeryzacji oraz stwierdzono, że kompleksy te umożliwiają otrzymanie wielkocząsteczkowego polietylenu o dobrych własnościach mechanicznych i podwyższonej odporności termicznej.
Comentario
1978
Elecciones francesas : Balance de una experiencia/y2
1978
El dilema socialista
1978
Zusammenfassung der Diskussion Teil II. Klinische Anwendung
1978
Considerazioni sul trattamento fiscale dell'impresa agricola
1978
Проблемы научного управления социалистическим обществом
1978
В статьях сборника приводятся результаты обсуждений вопросов научного управления социалистическим обществом: метод планирования путем разработки целевых комплексных программ, опыт разработки социального планирования, опыт создания системы автоматизированных банков данных республиканской автоматизированной системы. В области совершенствования информации, которая является центральной категорией управления, проводится идея ликвидации элементов стихийности, разобщенности, несовместимости, плюрализма информационных языков и создания их совместимости, интеграции и единства с естественным языком.
Global solar radiation in Italy
1978
Zusammenfassung der Diskussion Teil I: Pharmakologie, Pharmakokinetik, Metabolismus
1978
Chemotherapy of bladder tumours.
1978
Nachweis der verbesserten Kohlenhydrattoleranz bei juvenilen Diabetikern durch Ein-satz eines neuen Saccharase-Hemmers
1978
Wir haben versucht mit Hilfe eines Glykosidhydrolasen-Inhibitors die Aufnahme von Kohlenhydraten zu vermindern und somit eine Glattung im Tagesprofil und eine Insulineinsparung zu erreichen. Dabei wurde untersucht, ob eine Verbesserung der Glukosetoleranz durch Verminderung der postprandialen Blutzuckerspritzen, Senkung der Nuchternblutzuckerwerte und geringeren Insulinverbrauch zu erreichen sei. Es wurden an der „kunstlichen B-Zelle“ zehn juvenile Diabetiker uber je 2mal 48 Std beobachtet. Die Patienten hielten wahrend des Behandlungszeitraumes ihre bisherige Insulin-Therapie und isokalorische Ernahrung bei. In randomisierter Reihenfolge bekamen durch 2–3 Wochen Placebo und dann eine gleic…
Producción y comercialización vinícola en el Camp de Morvedre en el siglo XVII
1978
Aproximación al estudio del régimen señorial valenciano en el siglo XVIII
1978
EL PAIS, un diario independiente y una empresa pro?spera
1978
No es un artículo de José Vidal-Beneyto sino una noticia firmada por la redacción de ""El País"" donde aparece una referencia a Vidal-Beneyto en tanto que socio fundador del diario."
37. zinātniskās konferences programma un ielūgums
1978
Reductive Metabolism of P-Nitrobenzoic Acid and Nitrazepam in the Isolated Perfused Rat Liver in the Presence of Ethanol
1978
Reductive metabolism of aromatic nitro compounds has been shown to play a minor role under aerobic conditions and to reach maximal activities under anoxia (Jonen-Kern et al., Xenobiotica, in press). We have shown that in the presence of ethanol maximal activities can be obtained even under aerobic conditions.
Metabolic Inactivation of Reactive Metabolites
1978
ABSTRACT Many compounds which are not electrophilically reactive as such are transformed by mammalian enzymes to reactive metabolites which are, in many cases, responsible for cytotoxic, mutagenic and/or carcinogenic effects of the compounds in question. The essential role of activating systems in this situation has become common knowledge during the last decade. However, many reactive metabolites are also subject to inactivation by mammalian enzymes. This important parameter is frequently not taken into account. Compounds possessing aromatic or olefinic moieties are very widely occurring and activation of these often proceeds via an electrophilically reactive epoxide. This may be transform…
CLINICAL AND NEUROPHYSIOLOGICAL FINDINGS IN 47 LONG-TERM SURVIVORS OF CHILDHOOD MALIGNANCIES TREATED WITH VARIOUS DOSES OF VINCRISTINE
1978
ABSTRACT 96 long-term survivors of cancer in childhood were reexamined after succesful therapy. In 49 who had not been treated with VINCRISTINE (VCR) reflex status and motor conduction velocities were normal. In contrast, 47-after treatment with VCR-had loss of deep tendon reflexes in a high rate and a prolongation of sensory CV independent of the 1 total cumulative dose of VCR, 2 application mode according to different treatment regimen, 3 time interval since the last injections of the drug, 4 age of children at onset of therapy.
Complexes of organometallic compounds. XLVIII. Mössbauer and other studies on pyrazine derivatives of tin(IV) compounds. A relationship between isome…
1978
Abstract Adducts RSnCl 3 ·pyz (R = Me, Bu n , Oct n , Ph; pyz = pyrazine) have been synthesized and characterized in the solid state. It has been determined that RSnCl 3 ·pyz are polymeric compounds, where the ligand acts as bridging bis-monodentate and the tin atoms attain the coordination number six. This has been duduced from: i) temperature dependent Mossbauer spectroscopy; ii) the correlation between Mossbauer isomer shift, δ, and electrical charge on tin, Q Sn , concerning pyrazine adducts of RSnCl 3 and others; iii) an infrared study of the coordinated ligand in RSnCl 3 ·pyz. Other implications of the Mossbauer T dependent study ( e.g. , the decrease of the Debye temperature in RSnCl…