showing 36 of ~574560 from 574555 documents
Enhanced Reflectivity Change and Phase Shift of Polarized Light: Double Parameter Multilayer Sensor
2022
Herein, the concept of point of darkness based on polarized light phase difference and absorption of light is demonstrated by simulations using low refractive index and extinction coefficient semiconductor and dielectric, and high refractive index nonoxidizing metal multilayer thin film structures. Several multilayer sensor configurations show great sensitivity to thickness and refractive index variation of the detectable material by measuring the reflectivity ratio {\Psi} and phase shift {\Delta}. Focus is on such multilayers, which have sensitivity to both parameters ({\Psi}, {\Delta}) in the visible spectral range, thus opening the possibility for further research on a new biomedical sen…
“Hot Case-workers and Squint-eyed Whores” - Sexual Harassment of Norwegian Social- and Health Care Students in Practical Training
2022
Sexual harassment is a societal challenge. Youth, women, students, and health care professionals are some of the groups most at risk for experiencing sexual harassment. In this study, we examine how higher education institutions and practice institutions handle sexual harassment and how students in practical training experience and cope with sexual harassment. A survey and in-depth interviews were conducted among nursing students and social work students at one Norwegian university. Our results indicate that students experience sexual harassment during practice that is an obligatory part of training, that guidance and follow-up are often lacking, and that they experience negative consequenc…
Changes in Body Composition, Energy Metabolites and Electrolytes During Winter Survival Training in Male Soldiers
2022
The aim of this study was to examine changes in body composition, energy metabolites and electrolytes during a 10-day winter survival training period. Two groups of male soldiers were examined: the REC group (n = 26; age 19.7 ± 1.2 years; BMI 23.9 ± 2.7) had recovery period between days 6 and 8 in the survival training, whereas the EXC group (n = 42; age 19.6 ± 0.8 years; BMI 23.1 ± 2.8) did not. The following data were collected: body composition (bioimpedance), energy balance (food diaries, heart rate variability measurements), and biomarkers (blood samples). In survival training, estimated energy balance was highly negative: −4,323 ± 1,515 kcal/d (EXC) and −4,635 ± 1,742 kcal/d (REC). Be…
The Potential of a Separated Electric Compound Spark-Ignition Engine for Hybrid Vehicle Application
2022
Abstract In-cylinder expansion of internal combustion engines based on Diesel or Otto cycles cannot be completely brought down to ambient pressure, causing a 20% theoretical energy loss. Several systems have been implemented to recover and use this energy such as turbocharging, turbomechanical and turbo-electrical compounding, or the implementation of Miller cycles. In all these cases however, the amount of energy recovered is limited allowing the engine to reach an overall efficiency incremental improvement between 4% and 9%. Implementing an adequately designed expander–generator unit could efficiently recover the unexpanded exhaust gas energy and improve efficiency. In this work, the appl…
How agriculture, connectivity and water management can affect water quality of a mediterranean coastal wetland
2022
The Natural Park of Albufera (Valencia, Spain) is an important Mediterranean coastal wetland that suffers continuous environmental effects from human activities and water uses, mainly related to agriculture and urban/industrial sewage discharges. The aim of this research was to assess the water quality of the different aquatic environments of this wetland, taking into account the connection between them, the agricultural impact and the management of irrigation water. The UE Water Framework Directive was followed in order to evaluate the ecological and trophic status of water systems. Spatial approaches were used to integrate physicochemical data into GIS vector layers to map the more proble…
“I feel many contradictory emotions” : Finnish mothers' discursive struggles with motherhood
2022
Objective The aim of the study was to facilitate the understanding and interpretation of multiple aspects of working with mothers by examining Finnish mothers' mothering discourses and the interplay among these discourses. Background According to relational dialectics theory, discourses are systems of meaning that are coproduced in interaction. Although discursive research on motherhood has identified various discourses, research on the interplay among competing motherhood discourses is in its infancy. Method Qualitative questionnaire data from 479 Finnish mothers of infants were analyzed using contrapuntal analysis. Mothers' responses to three open-ended questions were analyzed inductively…
Revascularization technique for a long occlusive lesion in a case of symptomatic chronic occlusion of the internal carotid artery
2022
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL.
2022
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing future cardiovascular events. Low-density lipoproteins (LDL) have been successfully targeted, and their reduction is one of the key preventing measures in patients with atherosclerotic disease. LDL particles are pivotal for the formation and progression of atherosclerotic plaques; yet, they are quite heterogeneous, and smaller, denser LDL species are the most atherogenic. These particles have greater arterial entry and retention, higher susceptibility to oxidation, as well a…
Hematological and ventilatory responses to a 3900 m altitude sojourn in an elite wheelchair-marathoner.
2022
This case study aimed to report blood markers and resting respiratory rate (RR) oscillations at sea level, during a 5-wk 3900 m altitude sojourn, and after returning to sea level in a 36-year-old professional wheelchair marathoner. Outcome measures plasma erythropoietin (EPO) concentration, hemoglobin, reticulocytes count, erythrocytes and hematocrit as well as RR were measured upon wakening 7-weeks pre-altitude, 7-days pre-altitude, 35 hours after arrival to altitude, on days 8, 15, 21, 28 and 35 at altitude, 6 and 16 days after returning to sea level. EPO increased up to 259 % (31.6 U l-1) 35 hours upon arrival at altitude and decreased below pre-altitude level (12.2 U l-1) on the 21st da…
Disagreement, Points of View, and Truth-Relativism
2022
AbstractTruth-relativism is the claim that the truth of statements is dependent on the context in which they are made. In this article, truth-relativism is considered as a way to explain disagreements. Viewpoint relativism, a recent version of truth-relativism, is introduced as a useful framework to analyse how truth-relativism approaches disagreements. Viewpoint relativism is based on contextual semantics and the logic of viewpoint, which is a two-dimensional modal logic. In viewpoint relativism, the central concept is a point of view in relation to which truth claims are evaluated. Viewpoint relativism is compared to the truth-relativism of Peter Lasersohn and John MacFarlane. Finally, tr…
Smoking in hospitalized patients. A great opportunity
2022
The objective of this study is to describe the characteristics of smokers admitted to different medical and surgical services in a university hospital and the perception of patients regarding the need for a specialized intervention. The sample comprises a total of 307 patients (mean age of 59.4 years), being 40% (n = 123) non-smokers, 42.7% (n = 131) ex-smokers, and 17.3% (n = 53) smokers. The average consumption of smokers was 22.2 cigarettes / day and the severity of nicotine dependence evaluated with the Fagerstrom test exceeded 5 points in more than half of the sample. On the other hand, 77.7% had made at least one previous attempt to quit tobacco use. Almost the entire sample (89.9 %) …
An Epigenetic Alphabet of Crop Adaptation to Climate Change
2022
Crop adaptation to climate change is in a part attributed to epigenetic mechanisms which are related to response to abiotic and biotic stresses. Although recent studies increased our knowledge on the nature of these mechanisms, epigenetics remains under-investigated and still poorly understood in many, especially non-model, plants, Epigenetic modifications are traditionally divided into two main groups, DNA methylation and histone modifications that lead to chromatin remodeling and the regulation of genome functioning. In this review, we outline the most recent and interesting findings on crop epigenetic responses to the environmental cues that are most relevant to climate change. In additi…
KRAS-G12C Mutation in One Real-Life and Three Population-Based Nordic Cohorts of Metastatic Colorectal Cancer
2022
Background: KRAS mutations, present in over 40% of metastatic colorectal cancer (mCRC), are negative predictive factors for anti-EGFR therapy. Mutations in KRAS-G12C have a cysteine residue for which drugs have been developed. Published data on this specific mutation are conflicting; thus, we studied the frequency and clinical characteristics in a real-world and population-based setting. Methods: Patients from three Nordic population-based cohorts and the real-life RAXO-study were combined. RAS and BRAF tests were performed in routine healthcare, except for one cohort. The dataset consisted of 2,559 patients, of which 1,871 could be accurately classified as KRAS, NRAS, and BRAF-V600E. Demog…
The differences of Slovenian and Italian daily practices experienced in the first wave of covid-19 pandemic
2022
Abstract Background The COVID-19 pandemic situation with the lockdown of public life caused serious changes in people's everyday practices. The study evaluates the differences between Slovenia and Italy in health-related everyday practices induced by the restrictive measures during first wave of the COVID-19 pandemic. Methods The cross-sectional cohort study examined changes through an online survey conducted in nine European countries from April 15–28, 2020. The survey included questions from a simple activity inventory questionnaire (SIMPAQ), the European Health Interview Survey, and some other questions. To compare difference in changes between European countries we examined Italy with s…
Measurement of the e+e−→ωπ0π0 cross section at center-of-mass energies from 2.0 to 3.08 GeV
2022
Nordic homicide in deep time : lethal violence in the early modern era and present times
2022
Nordic Homicide in Deep Time draws a unique and detailed picture of developments in human interpersonal violence and presents new findings on rates, patterns, and long-term changes in lethal violence in the Nordics. Conducted by an interdisciplinary team of criminologists and historians, the book analyses homicide and lethal violence in northern Europe in two eras – the 17th century and early 21st century. Similar and continuous societal structures, cultural patterns, and legal cultures allow for long-term and comparative homicide research in the Nordic context. Reflecting human universals and stable motives, such as revenge, jealousy, honour, and material conflicts, homicide as a form of h…
Cubic color charge correlator in a proton made of three quarks and a gluon
2022
The three point correlation function of color charge densities is evaluated explicitly in light cone gauge for a proton on the light cone. This includes both $C$-conjugation even and odd contributions. We account for perturbative corrections to the three-quark light cone wave function due to the emission of an internal gluon which is not required to be soft. We verify the Ward identity as well as the cancellation of UV divergences in the sum of all diagrams so that the correlator is independent of the renormalization scale. It does, however, exhibit the well known soft and collinear singularities. The expressions derived here provide the $C$-odd contribution to the initial conditions for hi…
Questioni di legittimità costituzionale dell’art. 4 del d.l. n. 44 del 2021. Spunti di riflessione a margine dell’ordinanza n. 38/2022 del Consiglio …
2022
L'articolo affronta il tema dell'obbligo vaccinale con particolare riferimento al dibattitto giurisprudenziale dinanzi al giudice amministrativo
Section: Advanced Composites and Applications (15th February, 2022, Riga, Latvia) : Book of Abstracts
2022
The section ‘Advanced Composites and Applications’ was organized by the Institute for Mechanics of Materials of the University of Latvia (LU MMI) on 15.02.2022 as a part of the annual 80th scientific conference of the University of Latvia. It was organized remotely in Zoom. The official language of the section was English. The duration of the presentation was 10-15 minutes. The section was devoted to the discussion of the recent results within following topics: structure and properties of polymers and polymer-based composites, long-term properties, creep, and environmental ageing, composites for advanced applications, mechanical aspects of technology, multifunctional properties.
The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international …
2022
BACKGROUND: . High-quality comprehensive data on short-/long-term physical/mental health effects of the COVID-19 pandemic are needed. METHODS: . The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is an international, multi-language (n=30) project involving >230 investigators from 49 countries/territories/regions, endorsed by national/international professional associations. COH-FIT is a multi-wave, on-line anonymous, cross-sectional survey [wave 1: 04/2020 until the end of the pandemic, 12 months waves 2/3 starting 6/24 months threreafter] for adults, adolescents (14-17), and children (6-13), utilizing non-probability/snowball and representative samp…
Corrigendum: Meaning in Life Mediates Between Emotional Deregulation and Eating Disorders Psychopathology: A Research From the Meaning-Making Model o…
2022
Long‐term molecular differences between resilient and susceptible mice after a single traumatic exposure
2022
Post-traumatic stress disorder (PTSD) is a heterogeneous disorder induced by trauma, resulting in severe long-term impairments of an individual's mental health. PTSD does not develop in every individual and, thus, some individuals are more resilient. However, the underlying molecular mechanisms are poorly understood. Here, we aimed to elucidate these processes.We used a single-trauma PTSD model in mice to induce long-term maladaptive behaviours and profiled the mice 4 weeks after trauma into resilient or susceptible individuals. The classification of phenotype was based on individual responses in different behavioural experiments. We analysed microbiome, circulating endocannabinoids, and lo…
Tsunami Vulnerability Evaluation for a Small Ancient Village on Eastern Sicily Coast
2022
The Ionian sea is prone to tsunamis due to its proximity to the Calabrian subduction zone, which is one of the major tsunamigenic areas of the Mediterranean. The tsunami disaster risk is, nowadays, significantly higher due to the increased exposure of buildings as a result of the economic and touristic growth of the Mediterranean coastal areas. This study focuses on Marzamemi, a small village in the western coast of Sicily, since its morphology and human presence amplify the need to assess its buildings’ vulnerability. The main objective of this research is to quantify the building vulnerability to tsunami hazards using a physical and realistic tsunami scenario. For this purpose, the relati…
‘Life is team play’: social inclusion of people with intellectual disabilities in the context of Special Olympics
2022
This article provides insights from an empirical study on the meaning of social inclusion for Finnish athletes with intellectual disabilities (ID) who participate in Special Olympics (SO). A further objective was to explore the athletes’ perceptions of the role SO has played in their lives regarding their personal experiences of social inclusion. Data were transcripts of five focus group interviews carried out with a total of 31 participants during the last SO World Winter Games in 2017. The content was analysed with the aim of identifying the main themes in the athletes’ conversations about social inclusion. Three main themes were identified: inclusion as a contrast to past discrimination;…
Assessing the economic profitability of Paulownia as a biomass crop in Southern Mediterranean area
2022
The increase of renewable energy production worldwide, occurred in the last years, is also attributable to some agroforestry species cultivated according to the short rotation coppice technique. Although these species are able of enhancing abandoned or marginal land leading to numerous environmental benefits, an increasing number of farmers are introducing them in place of agricultural crops. Therefore, since for a farmer economic sustainability is one of the main factors to introduce a biomass crop, the study aimed at evaluating the profitability of Paulownia, a species that has been spreading in recent years. In particular, an economic analysis has been carried out in a Southern Italian f…
Allochthony, fatty acid and mercury trends in muscle of Eurasian perch (Perca fluviatilis) along boreal environmental gradients
2022
Environmental change, including joint effects of increasing dissolved organic carbon (DOC) and total phosphorus (TP) in boreal northern lakes could potentially affects food web energy sources and the biochemical composition of organisms. These environmental stressors are enhanced by anthropogenic land-use and can decrease the quality of polyunsaturated fatty acids (PUFAs) in seston and zooplankton, and therefore, possibly cascading up to fish. In contrast, the content of mercury in fish increases with lake browning potentially amplified by intensive forestry practises. However, there is little evidence on how these environmental stressors simultaneously impact beneficial omega-3 fatty acid …
Prevalence, Incidence, and Progression of Cognitive Impairment, No Dementia Among Rural-Dwelling Chinese Older Adults
2022
Background: Few studies have examined occurrence and progression of cognitive impairment, no dementia (CIND) in rural China. Objective: To determine the prevalence and incidence of CIND in rural-dwelling Chinese older adults, and to examine risk and protective factors associated with progression to CIND and dementia. Methods: This population-based study included 2,781 dementia-free participants (age≥65 years) who were examined at baseline (2014) and followed in 2018. Demographic, epidemiological, clinical, and neuropsychological data were collected following a structured questionnaire. We defined CIND according to subjective cognitive complaints and the age- and education-specific Mini-Ment…
New insights into the use of rhizobia to mitigate soil N2O emissions
2022
Agriculture is a major anthropogenic source of the greenhouse gas N2O, which is also involved in stratospheric ozone depletion. While the use of rhizobial inoculants has already been reported as an emerging option for mitigating soil N2O emissions, this study presents an in situ abatement of 70% of soil N2O emission using the strain nosZ+ G49 vs. nosZ− USDA138 in association with soybean. Therefore, we consider that the choice of the inoculant strain of a leguminous crop should take into account the capacity of strains to reduce nitrous oxide in addition to their N fixation capacity. This study also clearly suggests that this mitigation option could be considered not only for soybean but al…
Applications of intersection numbers in physics
2022
In this review I discuss intersection numbers of twisted cocycles and their relation to physics. After defining what these intersection number are, I will first discuss a method for computing them. This is followed by three examples where intersection numbers appear in physics. These examples are: tree-level scattering amplitudes within the the CHY-formalism, reduction of Feynman integrals to master integrals and correlation functions on the lattice.
Of Cockroaches and Symbionts: Recent Advances in the Characterization of the Relationship between Blattella germanica and Its Dual Symbiotic System
2022
This article belongs to the Collection Feature Review Papers for Life.
Differentiation of hepatocellular adenoma by subtype and hepatocellular carcinoma in non-cirrhotic liver by fractal analysis of perfusion MRI.
2022
Abstract Background To investigate whether fractal analysis of perfusion differentiates hepatocellular adenoma (HCA) subtypes and hepatocellular carcinoma (HCC) in non-cirrhotic liver by quantifying perfusion chaos using four-dimensional dynamic contrast-enhanced magnetic resonance imaging (4D-DCE-MRI). Results A retrospective population of 63 patients (47 female) with histopathologically characterized HCA and HCC in non-cirrhotic livers was investigated. Our population consisted of 13 hepatocyte nuclear factor (HNF)-1α-inactivated (H-HCAs), 7 β-catenin-exon-3-mutated (bex3-HCAs), 27 inflammatory HCAs (I-HCAs), and 16 HCCs. Four-dimensional fractal analysis was applied to arterial, portal v…
Andricus cydoniae Giraud, 1859 Junior Synonym of Cynips coni-fica Hartig, 1843, as Experimentally Demonstrated (Hymenoptera: Cynipidae: Cynipini)
2022
We demonstrated the life cycle closure of Cynips conifica Hartig, 1843 (presently Andricus conificus), previously supposed on the basis of molecular data, and the identity of the sexual generation, through laboratory experiments. As a consequence, Andricus cydoniae Giraud, 1859 became a junior synonym of A. conificus (Hartig, 1843). We provide illustrations and a diagnosis for adults and galls, observations on biology, and information on distribution. Moreover, as sexual galls of A. conificus cannot be distinguished from those of Andricus multiplicatus, a detailed comparison between sexual galls and adults of these two species is reported.
Two-Tier Care Pathways for Liver Fibrosis Associated to Non-Alcoholic Fatty Liver Disease in HIV Mono-Infected Patients.
2022
(1) Background: Developing strategies to identify significant liver fibrosis in people with HIV (PWH) is crucial to prevent complications of non-alcoholic fatty liver disease (NAFLD). We aim to investigate if five simple serum biomarkers applied to PWH can optimize a care pathway to identify significant liver fibrosis defined by transient elastography (TE). (2) Methods: A two-tier fibrosis pathway was applied to three prospective cohorts of PWH undergoing TE with CAP. NAFLD was diagnosed as a controlled attenuation parameter ≥ 248 dB/m. Five simple fibrosis biomarkers (FIB-4 < 1.3, BARD score 0–1, NAFLD fibrosis score < −1.455, AST:ALT ratio < 0.8 and APRI < 0.5) …
GPCR Inhibition in Treating Lymphoma
2022
G protein-coupled receptors (GPCRs) are important classes of cell surface receptors involved in multiple physiological functions. Aberrant expression, upregulation, and mutation of GPCR signaling pathways are frequent in many types of cancers, promoting hyperproliferation, angiogenesis, and metastasis. Recent studies showed that alterations of GPCRs are involved in different lymphoma types. Herein, we review the synthetic strategies to obtain GPCR inhibitors, focusing on CXCR4 inhibitors which represent most of the GPCR inhibitors available in the market or under preclinical investigations for these diseases.
Talent development abroad. Young football players’ experiences and challenges on being recruited to English academies
2022
The aim of the current study was to gain insight into talented Norwegian football players who made a club transfer to an English football academy, by investigating the players’ choice of academy, main challenges upon arrival, how they settled in both athletically and socially and their day-to-day life in the academy. Eight Norwegian players registered in an English professional football academy between the ages of 16 and 18 years were interviewed in retrospect. The challenges that the players met were mostly related to their efforts to develop as players, such as going into an extremely high-performance environment, which was quite different from what they perceived in their original club. …
EMBER—Embedding Multiple Molecular Fingerprints for Virtual Screening
2022
In recent years, the debate in the field of applications of Deep Learning to Virtual Screening has focused on the use of neural embeddings with respect to classical descriptors in order to encode both structural and physical properties of ligands and/or targets. The attention on embeddings with the increasing use of Graph Neural Networks aimed at overcoming molecular fingerprints that are short range embeddings for atomic neighborhoods. Here, we present EMBER, a novel molecular embedding made by seven molecular fingerprints arranged as different “spectra” to describe the same molecule, and we prove its effectiveness by using deep convolutional architecture that assesses ligands&…