showing 36 of ~574560 from 574555 documents
Large shape staggering in neutron-deficient Bi isotopes
2021
The changes in the mean-square charge radius (relative to 209Bi), magnetic dipole, and electric quadrupole moments of 187,188,189,191Bi were measured using the in-source resonance-ionization spectroscopy technique at ISOLDE (CERN). A large staggering in radii was found in 187,188,189Big, manifested by a sharp radius increase for the ground state of 188Bi relative to the neighboring 187,189Big. A large isomer shift was also observed for 188Bim. Both effects happen at the same neutron number, N=105, where the shape staggering and a similar isomer shift were observed in the mercury isotopes. Experimental results are reproduced by mean-field calculations where the ground or isomeric states were…
A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds
2021
Background: A wide range of techniques has been developed over the past decades to characterize amyloid-β (Aβ) pathology in mice. Until now, no method has been established to quantify spatial changes in Aβ plaque deposition due to targeted delivery of substances using ALZET® pumps. Objective: Development of a methodology to quantify the local distribution of Aβ plaques after intracerebral infusion of compounds. Methods: We have developed a toolbox to quantify Aβ plaques in relation to intracerebral injection channels using Zeiss AxioVision® and Microsoft Excel® software. For the proof of concept, intracerebral stereotactic surgery was performed in 50-day-old APP-transgenic mice injected wit…
La novela negra como «transgénero»: éticas transnacionales en la feminización del canon
2021
El presente trabajo supone una pequeña aportación en la búsqueda de modelos de análisis «interseccionales» (Hill Collins y Bilge 2016/2020) que permitan analizar desde el feminismo las denominadas «transnacionalidades mínimas» (Lionnet y Shih 2005). Modelos que, en definitiva, superen la todavía fuerte adscripción de muchos feminismos a los bloques geotextuales heredados del patriarcado. Desde sus orígenes, los feminismos han empleado la traducción para subvertir los géneros textuales (Godard 1987: 6; Simon 1996: 46) y, en definitiva, para luchar contra el ostracismo literario que comparten con otros colectivos de la lucha postcolonial. Unas y otros han visto su diálogo y mutua comprensión …
Synthesis of Polycyclic Indolines by Utilizing a Reduction/Cyclization Cascade Reaction
2021
European journal of organic chemistry 2021(45), 6097-6101 (2021). doi:10.1002/ejoc.202101191
An exon junction complex‐independent function of Barentsz in neuromuscular synapse growth
2021
The exon junction complex controls the translation, degradation, and localization of spliced mRNAs, and three of its core subunits also play a role in splicing. Here, we show that a fourth subunit, Barentsz, has distinct functions within and separate from the exon junction complex in Drosophila neuromuscular development. The distribution of mitochondria in larval muscles requires Barentsz as well as other exon junction complex subunits and is not rescued by a Barentsz transgene in which residues required for binding to the core subunit eIF4AIII are mutated. In contrast, interactions with the exon junction complex are not required for Barentsz to promote the growth of neuromuscular synapses.…
On existence of joins and meets under the star order in strong Rickart rings
2021
Effect of Foot Orthoses and Shoes in Parkinson's Disease Patients : A PRISMA Systematic Review
2021
[Abstract] Reduced plantar foot sensation, postural instability, and gait difficulties are characteristic of Parkinson´s disease patients. A systematic review was carried out to determine the effect of the different types of insoles and shoes in these patients. Several databases were used to search for relevant articles reporting Parkinson´s disease patients undergoing treatment with any type of insole and footwear. All titles and abstracts were reviewed independently by two reviewers and the available data were extracted. The study eligibility criteria were any type of experimental study that included Parkinson’s disease patients treated with any type of insole or footwear. Eight studies w…
From Ivory Tower to Social Arena:
2021
International audience
Influenza Vaccination After Myocardial Infarction:A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial
2021
Background: Observational and small, randomized studies suggest that influenza vaccine may reduce future cardiovascular events in patients with cardiovascular disease. Methods: We conducted an investigator-initiated, randomized, double-blind trial to compare inactivated influenza vaccine with saline placebo administered shortly after myocardial infarction (MI; 99.7% of patients) or high-risk stable coronary heart disease (0.3%). The primary end point was the composite of all-cause death, MI, or stent thrombosis at 12 months. A hierarchical testing strategy was used for the key secondary end points: all-cause death, cardiovascular death, MI, and stent thrombosis. Results: Because of the COV…
SARS‐CoV ‐2‐reactive antibody detection after SARS‐CoV ‐2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the S…
2021
This is a multicenter prospective observational study which included a large cohort (n = 397) of allogeneic (allo-HSCT) (n = 311) and autologous (ASCT) hematopoietic stem cell transplant (n = 86) recipients who were monitored for antibody detection within 3 to 6 weeks after complete SARS-CoV-2 vaccination from February 1st 2021 to July 20th 2021. Most patients (n = 387, 97.4%) received mRNA-based vaccines. Most of recipients (93%) were vaccinated more than 1 year after transplant. Detectable SARS-CoV-2-reactive antibodies were observed in 242 (78%) of allo-HSCT and in 73 (85%) of ASCT recipients. Multivariate analysis in allo-HSCT recipients identified lymphopenia <1x109 /mL [Odds ratio (OR…
Diarylethenes in Optically Switchable Organic Light-Emitting Diodes: Direct Investigation of the Reversible Charge Carrier Trapping Process
2021
Advanced optical materials 10, (2021). doi:10.1002/adom.202101116
Product Placement Bibliometric Study: Generic Journals Versus Specific-Communication Journals
2021
Media fragmentation represents new challenges for product placement strategies to become an increasingly effective way to reach consumers and non-users. In this frame, this paper has been developed with three main objectives: (i) to carry on a performance analysis to measure the visibility/impact of the scientific product in product placement (most cited authors, journals, and themes), (ii) to visually present the scientific structure by topics of research in product placement as well as its evolution to identify future research lines, and (iii) to compare both objectives in generic journals and specific communication ones. To this end, the resources in the Web of Science Citation Index wer…
New ß-decaying state in 214Bi
2021
Asymmetric Methods for Carbon‐Fluorine Bond Formation
2021
The energy spectrum of cosmic rays beyond the turn-down around 1017 eV as measured with the surface detector of the Pierre Auger Observatory
2021
The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargüe. We are very grateful to the following agencies and organizations for financial support: Argentina – Comisión Nacional de Energía Atómica; Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargüe; NDM Holdings and Valle Las Leñas; in gratitude for their continuing cooperation over land access; Australia – the Australian Research Council; Be…
New beta-decaying state in Bi-214
2021
13 pags., 7 figs., 3 tabs.
Sodium-glucose cotransporter type 2 inhibitors prevent ponatinib-induced endothelial senescence and disfunction: A potential rescue strategy
2021
Background: Ponatinib (PON), a third-generation tyrosine kinase inhibitor (TKI), has proven cardiovascular toxicity, with no known preventing agents usable to limit such side effect. Sodium-glucose cotransporter type 2 (SGLT2) inhibitors are a new class of glucose-lowering agents, featuring favorable cardiac and vascular effects. Aims: We assessed the effects of the SGLT2 inhibitors empagliflozin (EMPA) and dapagliflozin (DAPA) on human aortic endothelial cells (HAECs) and underlying vasculo-protective mechanisms in an in vitro model of PON-induced endothelial toxicity. Methods and results: We exposed HAECs to PON or vehicle (DMSO) in the presence or absence of EMPA (100 and 500 nmol/L) or …
Photochemistry of HOSO2 and SO3 and Implications for the Production of Sulfuric Acid
2021
9 pags., 5 figs.
Aerosol responses to precipitation along North American air trajectories arriving at Bermuda
2021
North American pollution outflow is ubiquitous over the western North Atlantic Ocean, especially in winter, making this location a suitable natural laboratory for investigating the impact of precipitation on aerosol particles along air mass trajectories. We take advantage of observational data collected at Bermuda to seasonally assess the sensitivity of aerosol mass concentrations and volume size distributions to accumulated precipitation along trajectories (APT). The mass concentration of particulate matter with aerodynamic diameter less than 2.5 µm normalized by the enhancement of carbon monoxide above background (PM2.5/ΔCO) at Bermuda was used to estimate the degree of aerosol loss durin…
Dictionnaire Adégien : Néologismes, régionalismes et mots d'argot dans l'oeuvre d'A.D.G., maître du néo-polar et amoureux des mots
2021
International audience; Alain Fournier dit A.D.G. (1947-2004) est à côté de Jean-Patrick Manchette, Jean-Bernard Pouy, Frédéric H. Fajardie et d'autres encore, l'un des représentants les plus importants du néo-polar, ce courant littéraire né en France dans les années 1970 qui a révolutionné, en le rajeunissant, le genre policier français. Écrivain mais aussi journaliste, ce natif de Touraine s'est établi à Paris mais il a passé une partie de sa vie en Nouvelle-Calédonie. Ces lieux ont servi de décors à ses romans, mais ils ont été aussi de véritables sources lexicales pour cet amoureux des mots. Car tout au long de son oeuvre, A.D.G. a forgé un style vigoureux et poétique, au vocabulaire fo…
false
2021
Objectives: The present naturalistic study aims to investigate the differential effects of the patient’s and the therapist’s attachment representations on the attachment to the therapist as perceived by the patient, and their impact on self-esteem-change through psychotherapy.Methods: Attachment variables of N = 573 patients as well as N = 16 therapists were assessed. Attachment representations were measured for therapists and patients via the Bielefelder Questionnaire for Client Attachment Exploration, the Relationship Specific Attachment to Therapist Scales and the Adult Attachment Interview. The patient’s attachment to therapists was evaluated and patients’ self-esteem was measured via t…
Politicisation as a Speech Act: A Repertoire for Analysing Politicisation in Parliamentary Plenary Debates
2021
This chapter analyses the actual speech acts of politicisation among parliamentarians, which also makes it possible to set the current debates among European Union (EU) scholars in a wider context. My aim is to sketch a scheme for distinguishing different aspects of politicisation, referring to concepts of politics (sphere or activity and its specific aspects), to the politicisation of topics or persons, to its time dimensions (past, present, and future), to different activities of politicisation (adversaries, unintended changes, the actors themselves), as well as to opposing evaluations of politicisation. The data set consists of the plenary debates of the UK House of Commons, the (West) G…
The Boundless World of Cranioplasty: A Multicenter Retrospective Study and Therapeutic Flow-Chart Patient-Specific Based.
2021
Background Cranioplasty is both a functional and aesthetical therapeutic option. In the clinical scenario every cranioplasty's material is potentially qualified to achieve the goal of calvarian reconstruction but there is a lack of agreement about the optimum choice, especially between the heterologous ones. The choice of cranioplasty widely depends on surgeon's personal preferences. In this retrospective multicentric study a comparative analysis of hydroxyapatite or titanium cranioplasties was carried on analyzing the main factors considered by the surgeon to choose a material rather than another one. Our results and data were compared with those reported in the scientific literature and a…
Measuring Internet Gaming Disorder and Gaming Disorder: A Qualitative Content Validity Analysis of Validated Scales
2021
Numerous instruments have been developed to measure gaming-related health problems based on “internet gaming disorder” (IGD) in the third section of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) and “gaming disorder” (GD) in the International Classification of Diseases (11th rev.). However, the criteria in the manuals tend to be operationalized in numerous diverse ways, which can make screening outcomes incomparable. A content validity analysis is needed to reassess the relationships between the diagnostic criteria and the items that operationalize them. The IGD and GD criteria were divided into sematic components. A qualitative content validity analysis was carried o…
Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13.
2021
CYP2A13 enzyme is expressed in human extrahepatic tissues, while CYP2A6 is a hepatic enzyme. Reactions catalysed by CYP2A13 activate tobacco-specific nitrosamines and some other toxic xenobiotics in lungs.To compare oxidation characteristics and substrate-enzyme active site interactions in CYP2A13 vs CYP2A6, we evaluated CYP2A13 mediated oxidation characteristics of 23 coumarin derivatives and modelled their interactions at the enzyme active site.CYP2A13 did not oxidise six coumarin derivatives to corresponding fluorescent 7-hydroxycoumarins. The Km-values of the other coumarins varied 0.85-97 µM, Vmax-values of the oxidation reaction varied 0.25-60 min-1, and intrinsic clearance varied 26-…
Influential Periods in Longitudinal Clinical Cardiovascular Health Scores
2021
Abstract The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e., body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 year…
The Rise and Fall of Business Firms: A Stochastic Framework on Innovation, Creative
2021
© 2020, Cambridge University PressThe book ‘The Rise and Fall of Business Firms: A Stochastic Framework on Innovation, Creative Destruction and Growth’ by S.V. Buldyrev, F. Pammolli, M. Riccaboni a...
false
2021
Bulk stable nitrogen isotope values of the carbonate-bound organic matrix in bivalve shells (δ15NCBOM) are increasingly used to assess past food web dynamics, track anthropogenic nitrogen pollution and reconstruct hydrographic changes. However, it remains unresolved if the δ15NCBOM values are also affected by directed ontogenetic trends which can bias ecological and environmental interpretations. This very aspect is tested here with modern and fossil specimens of the long-lived ocean quahog, Arctica islandica, collected from different sites and water depths in the NE Atlantic Ocean. As demonstrated, δ15NCBOM values from the long chronologies show a general decrease through lifetime by −0.00…
Identifying childhood movement profiles and comparing differences in mathematical skills between clusters : A latent profile analysis
2021
The aims of this study were; 1) to identify different movement profiles in sixth graders, and 2) to investigate if there are differences in their mathematical basic (BasicMath) and problem solving (ProbSol) skills between existing movement profiles. The sample included 461 (223 girls, 238 boys) students with a mean age of 11.27 +/- .32 years from southern and middle Finland. A latent profile analysis (LPA) revealed four movement profiles: "poor movers", "average movers", "skilled movers" and "expert movers". These profiles differed substantially in their motor competence (MC) and health-related fitness (HRF). A multivariate analysis of variance (MANOVA) also revealed that "poor movers" and …
Dietary acrylamide and physical performance tests: A cross-sectional analysis
2021
Background Dietary acrylamide is found in certain foods, such as deep frying, baking and roasting, and is associated with higher inflammatory and oxidative stress parameters. The association between dietary acrylamide and physical performance has not yet been explored. The aim of the study was to investigate the relationship between dietary acrylamide intake and physical performance tests in a large cohort of North American individuals affected by knee osteoarthritis or at high risk for this condition. Methods Dietary acrylamide intake was obtained through a food frequency questionnaire and reported in quartiles and as an increase in deciles. Physical performance was explored using the 20-…
Performance‐determining factors in biathlon prone shooting without physical stress
2021
This study investigated the most important factors determining biathlon prone shooting performance. 10 female and 16 male biathletes (age 19.9 ± 2.9 years) from the national teams of Finland and Vuokatti-Ruka Sports Academy performed 65 biathlon prone shooting shots without physical stress under laboratory conditions. Shooting performance and multiple aiming point trajectory variables were measured together with an analysis of triggering force. Based on the aiming point trajectory data principal component analysis, we identified four technical components in biathlon prone shooting: stability of hold, aiming accuracy, cleanness of triggering and timing of triggering. Multiple regression anal…
Design and simulation of efficient combinational circuits based on a new XOR structure in QCA technology
2021
AbstractQuantum-dot cellular automata (QCA), due to its unique characteristics like low power consumption, nanoscale design, and high computing speed is considered as an emerging technology, and it can be used as an alternative for CMOS technology in circuit design for quantum computers in the near future. XOR gate has many applications in the design of digital circuits in QCA. In this paper, an efficient novel structure of XOR gate is proposed in QCA. Also, a novel 1-bit comparator circuit, 1-bit full adder, binary to gray and gray to binary convertor code based on the proposed XOR is designed and simulated using QCADesigner 2.0.3. The simulation results demonstrated that the proposed stru…
Anxious and status signaling: Examining the link between attachment style and status consumption and the mediating role of materialistic values
2021
Attachment theory has recently been recognized as a potentially fruitful avenue for studying consumer behavior. However, few studies have examined the relationship between attachment styles and consumer preferences. Based on literature suggesting that individuals with an anxious attachment style have a particularly strong need for attention, we conducted two studies with a total sample of over 2,000 participants, which tested and found that anxiously attached consumers displayed a higher propensity to purchase status-signaling goods than their counterparts with secure attachment styles. This effect was mediated by materialistic values, such that participants with an anxious attachment style…
A review of the subfamily Charipinae (Hymenoptera: Cynipoidea: Figitidae), hyperparasitoids potentially affecting the biological control of aphids
2021
Charipinae is an important subfamily of aphid hyperparasitoids. As aphids are some of the most significant pests in the world, studying the insect community associated with them is of crucial importance. Here, we review the biological information available on Charipinae. The information has been grouped into different sections: (a) historical background; (b) morphological and ecological features; (c) phylogenetic relationships; (d) overview of aphid biology and biological control; (e) evolutionary history; and (f) future perspectives. After this review, it is evident that there are still some aspects of charipine taxonomy and biology that remain elusive: (a) reliability and improvement of h…
Deficient Interhemispheric Connectivity Underlies Movement Irregularities in Parkinson’s Disease
2021
Background: Movement execution is impaired in patients with Parkinson’s disease. Evolving neurodegeneration leads to altered connectivity between distinct regions of the brain and altered activity at interconnected areas. How connectivity alterations influence complex movements like drawing spirals in Parkinson’s disease patients remains largely unexplored. Objective: We investigated whether deteriorations in interregional connectivity relate to impaired execution of drawing. Methods: Twenty-nine patients and 31 age-matched healthy control participants drew spirals with both hands on a digital graphics tablet, and the regularity of drawing execution was evaluated by sample entropy. We recor…
Shedding some light on tricuspid intervention
2021
Background More than 1.6 million Americans have at least moderate to severe valvular tricuspid regurgitation, yet fewer than 8000 tricuspid valve operations are performed annually in the USA. The undertreatment for isolated tricuspid regurgitation might be related to the fact that in the past years no clear guidelines on 'how' and 'when' to treat tricuspid regurgitation were issued. Aims Sarris-Michopoulos and colleagues carried out a meta-analysis with the aim to investigate the role of tricuspid valve repair versus tricuspid valve replacement in patients with isolated tricuspid valve regurgitation. Material and methods Outcomes of patients with first-time surgery for isolated tricuspid va…