Chest CT in COVID-19 Pneumonia: Potentials and Limitations of Radiomics and Artificial Intelligence

2021

SARS-CoV-2 epidemics has resulted in an unprecedented global health crisis causing a high number of deaths with pneumonia being the most common manifestation. Chest CT is the best imaging modality to identify pulmonary involvement, but unfortunately there are no pathognomonic features for COVID-19 pneumonia, since many other infectious and non-infectious diseases may cause similar alterations. The adoption of artificial intelligence in biomedical imaging has the potential to revolutionize the identification, management, and the patient’s outcome. If adequately validated, it could be used as a support with predictive and prognostic purposes in symptomatic patients but also as a screening tes…

Probing the Paradigm of Promiscuity for N‐Heterocyclic Carbene Complexes and their Protein Adduct Formation

2021

Metal complexes can be considered a "paradigm of promiscuity" when it comes to their interactions with proteins. They often form adducts with a variety of donor atoms in an unselective manner. We have characterized the adducts formed between a series of isostructural N-heterocyclic carbene (NHC) complexes with Ru, Os, Rh, and Ir centers and the model protein hen egg white lysozyme by X-ray crystallography and mass spectrometry. Distinctive behavior for the metal compounds was observed with the more labile Ru and Rh complexes targeting mainly a surface l-histidine moiety through cleavage of p-cymene or NHC co-ligands, respectively. In contrast, the more inert Os and Ir derivatives were detec…

Evaluation of Physiological Parameters on Discomfort Glare Thresholds Using LUMIZ 100 Tool

2021

Purpose To assess the links between discomfort glare sensitivity and physiological factors such as eye biometry, refraction, skin phototype, age, and gender among a large sample of healthy human subjects. Methods A total of 489 participants who were 20 to 70 years old (241 men, 248 women) underwent discomfort glare threshold measurements via the LUMIZ 100. Eye biometry and optical quality were measured using a Zeiss IOLMaster 700 biometer and i.Profiler aberrometer. Iris color, skin tone, age, gender, eyeglasses use, chronotype, fatigue level, self-evaluation of light sensitivity, and time spent outdoors were determined. Statistical analysis was carried out using nonparametric Mann–Whitney …

Nurse knowledge and confidence on peripheral intravenous catheter insertion and maintenance in pediatric patients: A multicentre cross-sectional study

2021

Abstract Purpose To examine nursing knowledge and confidence of peripheral intravenous catheter insertion and maintenance in pediatric patients. Design and methods An online survey using validated questionnaires was conducted in ten (tertiary and district) hospitals in Indonesia from May to September 2020. Multivariable general linear models were used to investigate associations between nurses' characteristics and knowledge and confidence on the catheter insertion and maintenance score. Results A total of 413 out of 458 pediatric nurses completed the survey (a response rate of 90%). The mean score of the nurse knowledge on insertion was 18.9(±3.3) (maximum score: 21), and the maintenance sc…

Back Cover: Mobilization upon Cooling (Angew. Chem. Int. Ed. 35/2021)

2021

The neuropeptide Pth2 modulates social behavior and anxiety in zebrafish

2021

SummaryAnimal behavior is strongly context-dependent and behavioral performance is often modulated by internal state. In particular, different social contexts can alter anxiety levels and modulate social behavior. The vertebrate-specific neuropeptide parathyroid hormone 2 (pth2) is directly regulated by the presence or absence of conspecifics in zebrafish. As its cognate receptor, the parathyroid hormone 2 receptor (pth2r), is widely expressed across the brain, we tested fish lacking the functional Pth2 peptide in several anxiety-related and social paradigms. Rodents lacking PTH2 display increased anxiety-related behavior. Here we show that the propensity to react to sudden stimuli with an …

Abiotic Stress Tolerance of Coastal Accessions of a Promising Forage Species, Trifolium fragiferum

2021

Crop wild relatives are valuable as a genetic resource to develop new crop cultivars, better adapted to increasing environmental heterogeneity and being able to give high quality yields in a changing climate. The aim of the study was to evaluate the tolerance of different accessions of a crop wild relative, Trifolium fragiferum L., from coastal habitats of the Baltic Sea to three abiotic factors (increased soil moisture, trampling, cutting) in controlled conditions. Seeds from four accessions of T. fragiferum, collected in the wild, were used for experiments, and cv. ‘Palestine’ was used as a reference genotype. Plants were cultivated in asymbiotic conditions of soil culture. Treatments wer…

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning

2021

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitabil…

Device for Processing Micro-bores by Electrical Discharge Machining

2021

In recent years, there has been a growing trend to miniaturization parts. As a result, the processing technology must be partially evolved to produce a small surface, and then a microscopic surface. There are many of these technologies, and each has its advantages and disadvantages in the industry. Among these technologies, electric shock processing is used as an alternative with the required precision. Processing of very small wells by the method of electric emission is similar to that used in the processing of normal-sized machines and will be noted on paper. In this research, the authors developed a device for drilling holes 0.01–1 mm in diameter that can be installed in traditional non-…

Alma pater?

2021

Abstract In antiquity, breast milk was an elixir for every nursling. Despite this, there are but very few passages in the Bible that mention nursing. Curiously enough, the apostle Paul depicts himself as a nurse and provider of milk for his believers (1 Thess 2:7; 1 Cor 3:2). The motif of male providers of milk appears in numerous first and second century sources dependent on and independent from Paul. An overview of sources of Christ-believers from the first two centuries demonstrates that in characterizations of the lactating Godfather and the nursing Christ, the motifs of nursing and breastmilk continuously loses its real life connotation as something female thing and becomes predominant…

Three-dimensional core-collapse supernovae with complex magnetic structures: I. Explosion dynamics

2021

Magnetic fields can play a major role in the dynamics of outstanding explosions associated to violent events such as GRBs and hypernovae, since they provide a natural mechanism to harness the rotational energy of the central proto-neutron star and power relativistic jets through the stellar progenitor. As the structure of such fields is quite uncertain, most numerical models of MHD-driven core-collapse supernovae consider an aligned dipole as initial magnetic field, while the field's morphology can actually be much more complex. We present three-dimensional simulations of core-collapse supernovae with more realistic magnetic structures, such as quadrupolar fields and, for the first time, an…

Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial

2021

I.D.-L. is supported by the [FI_B 00256] from the FI-AGAUR Research Fellowship Program, Generalitat de Catalunya and M.M.-M is supported by the FPU17/00513 grant. a.-H. is supported by the [CD17/00122] grant and S.K.N. is supported by a Canadian Institutes of Health Research (CIHR) Fellowship. We also thank all the volunteers for their participation in and the personnel for their contribution to the PREDIMED-Plus trial. This research was funded by CiCYT [AGL2016-75329-R] and CIBEROBN from the Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia, Innovacion y Universidades, (AEI/FEDER, UE), Generalitat de Catalunya (GC) [2017SGR196]. The PREDIMED-Plus trial was supported by t…

Lignin Inter-Diffusion Underlying Improved Mechanical Performance of Hot-Pressed Paper Webs

2021

Broader use of bio-based fibres in packaging becomes possible when the mechanical properties of fibre materials exceed those of conventional paperboard. Hot-pressing provides an efficient method to improve both the wet and dry strength of lignin-containing paper webs. Here we study varied pressing conditions for webs formed with thermomechanical pulp (TMP). The results are compared against similar data for a wide range of other fibre types. In addition to standard strength and structural measurements, we characterise the induced structural changes with X-ray microtomography and scanning electron microscopy. The wet strength generally increases monotonously up to a very high pressing tempera…

A Trajectory-Driven 3D Channel Model for Human Activity Recognition

2021

This paper concerns the design, analysis, and simulation of a 3D non-stationary channel model fed with inertial measurement unit (IMU) data. The work in this paper provides a framework for simulating the micro-Doppler signatures of indoor channels for human activity recognition by using radiofrequency-based sensing technologies. The major human body segments, such as wrists, ankles, torso, and head, are modelled as a cluster of moving point scatterers. We provide expressions for the time variant (TV) speed and TV angles of motion based on 3D trajectories of the moving person. Moreover, we present mathematical expressions for the TV Doppler shifts and TV path gains associated with each movin…

Industry 4.0

2021

The aim of this chapter is not to create another systematic analysis of previously existing works but to present the results of these studies. This allows to identify the key characteristics of Industry 4.0, which are presented in a word cloud. This is a kind of summary of the diversity of the definitions and the basis for identifying the essence of Industry 4.0. In this chapter, the classic process of production management is characterized and any changes that have occurred (or will occur) as a result of the implementation of solutions of the Fourth Industrial Revolution are identified. Additionally, the challenges that production management may face in the age of Industry 4.0 are presente…

The ABCflux database: Arctic-Boreal CO<sub>2</sub> flux observations and ancillary information aggregated to monthly time…

2021

Abstract. Past efforts to synthesize and quantify the magnitude and change in carbon dioxide (CO2) fluxes in terrestrial ecosystems across the rapidly warming Arctic-Boreal Zone (ABZ) have provided valuable information, but were limited in their geographical and temporal coverage. Furthermore, these efforts have been based on data aggregated over varying time periods, often with only minimal site ancillary data, thus limiting their potential to be used in large-scale carbon budget assessments. To bridge these gaps, we developed a standardized monthly database of Arctic-Boreal CO2 fluxes (ABCflux) that aggregates in-situ measurements of terrestrial net ecosystem CO2 exchange and its derived …

Análisis del efecto Airbnb en la ciudad de Valencia. Situación actual (2020) y perspectivas de futuro / / / \ \ \ Analysis of the Airbnb effect in th…

2021

Resumen: Las ciudades experimentan cambios rápidos. Uno de estos tiene como elemento disruptivo el crecimiento del turismo, es decir, de la atractividad de determinados espacios urbanos que ha dado lugar a un aumento de la oferta para los visitantes, tanto de recursos como, sobre todo, de alojamiento. Un elemento clave para explicar este aumento de la oferta es el alquiler turístico o alquiler de corta duración a través de plataformas digitales, entre las que destaca Airbnb. En la ciudad de Valencia, este fenómeno ha experimentado un crecimiento espectacular durante el segundo decenio del presente siglo. A partir de un análisis detallado de la oferta turística en los barrios de Valencia, se…

Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases

2021

The heteroreceptor complexes present a novel biological principle for signal integration. These complexes and their allosteric receptor–receptor interactions are bidirectional and novel targets for treatment of CNS diseases including mental diseases. The existence of D2R-5-HT2AR heterocomplexes can help explain the anti-schizophrenic effects of atypical antipsychotic drugs not only based on blockade of 5-HT2AR and of D2R in higher doses but also based on blocking the allosteric enhancement of D2R protomer signaling by 5-HT2AR protomer activation. This research opens a new understanding of the integration of DA and 5-HT signals released from DA and 5-HT nerve terminal networks. The biologica…

The Process of Pregnancy: Paradoxical Temporalities of Prenatal Entities

2021

AbstractIn this article, we reflect on the particular temporal structure of pregnancies and prenatal entities with the aim to contribute to the field of the sociology of pregnancy. Medical models and technology shape today’s notion of pregnancy as a linear, nine-month developmental process that leads to the birth of a child. Through ultrasound technology and prenatal examinations, prenatal entities have thus historically gained a present ‘being’ as a developing, unborn child. While these ideas undoubtedly greatly influence the participants’ interpretations, a culturalistic perspective on time alone does not do justice to the phenomenon’s lived tensions and the temporal complexity of the phe…

Long-term decrease in Asian monsoon rainfall and abrupt climate change events over the past 6,700 years

2021

Significance The variability of the Asian summer monsoon (ASM) is important for the functioning of ecological and societal systems at regional to continental scales, but the long-term evolution and interannual variability of this system is not well understood. Here, we present a stable isotope–based reconstruction of ASM variability covering 4680 BCE to 2011 CE. Superimposed on a gradual drying trend, a rapid drop in mean annual precipitation (>40%) toward persistently drier conditions occurred in ∼1675 BCE. This megadrought caused regional forest deterioration and enhanced aeolian activity affecting Chinese ecosystems. We argue that this abrupt aridification starting ∼2000 BCE triggered wa…

Single-channel EEG-based subject identification using visual stimuli

2021

Electroencephalography (EEG) signals have been recently proposed as a biometrics modality due to some inherent advantages over traditional biometric approaches. In this work, we studied the performance of individual EEG channels for the task of subject identification in the context of EEG-based biometrics using a recently proposed benchmark dataset that contains EEG recordings acquired under various visual and non-visual stimuli using a low-cost consumer-grade EEG device. Results showed that specific EEG electrodes provide consistently higher identification accuracy regardless of the feature and stimuli types used, while features based on the Mel Frequency Cepstral Coefficients (MFCC) provi…

Out-of-plane transport of 1T-TaS2/graphene-based van der Waals heterostructures

2021

Due to their anisotropy, layered materials are excellent candidates for studying the interplay between the in-plane and out-of-plane entanglement in strongly correlated systems. A relevant example is provided by 1T-TaS2, which exhibits a multifaceted electronic and magnetic scenario due to the existence of several charge density wave (CDW) configurations. It includes quantum hidden phases, superconductivity and exotic quantum spin liquid (QSL) states, which are highly dependent on the out-of-plane stacking of the CDW. In this system, the interlayer stacking of the CDW is crucial for the interpretation of the underlying electronic and magnetic phase diagram. Here, thin-layers of 1T-TaS2 are …

Correction to: One Year of Dapaglifozin Add-On Therapy Ameliorates Surrogate Indexes of Insulin Resistance and Adiposity in Patients with Type 2 Diab…

2021

This study investigates the effects of dapagliflozin on the visceral adiposity index (VAI), lipid accumulation product (LAP), product of triglycerides and glucose (TyG) and triglycerides to HDL-cholesterol ratio (TG/HDL-C) in patients with type 2 diabetes mellitus (T2D). In this real-life study, dapaglifozin was added to metformin alone (group 1, no. 42) or insulin plus metformin (group 2, no. 58) in 100 T2D patients. In group 1, after 6 months of dapaglifozin addition, a significant decrease in BMI (p < 0.001), waist circumference (WC) (p < 0.001), systolic blood pressure (SBP) (p = 0.009), diastolic blood pressure (DBP) (p = 0.012), mean fasting blood glucose (FBG), post-breakfast glucose…

Análisis de la percepción de la peligrosidad de inundación en el municipio de Tavernes Blanques (Valencia, España). Su papel en la valoración del rie…

2021

Resumen: La Comunidad Valenciana alberga numerosas cuencas pequeñas de dinámica torrencial donde la ocurrencia de avenidas puede afectar a zonas urbanas. La alta ocupación de estas zonas y la baja percepción del riesgo por parte de las poblaciones contribuyen al aumento de la vulnerabilidad, suponiendo la amenaza un riesgo mayor para los grupos humanos. El presente estudio aborda el análisis de la percepción del riesgo de inundación por parte de la población de Tavernes Blanques (Valencia), municipio catalogado como de alto riesgo de inundación por la AVSRE. Para ello se lleva a cabo una encuesta a la población residente en el municipio, cuyos resultados muestran una baja percepción del rie…

Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study

2021

Results of studies on perfluoroalkyl substances (PFASs) and thyroid hormones (THs) are heterogeneous, and the mechanisms underlying the action of PFASs to target THs have not been fully characterized. We examined the relation between first-trimester maternal PFAS and TH levels and the role played by polymorphisms in the iodothyronine deiodinase 1 (DIO1) and 2 (DIO2) genes in this association. Our sample comprised 919 pregnant Spanish women (recruitment = 2003-2008) with measurements of perfluorohexanesulfonic acid (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorononanoic acid (PFNA), thyroid-stimulating hormone (TSH), total triiodothyronine (TT3), and fr…

I suffer from a serious rare disease : a challenge to sing and choreograph on TikTok

2021

Este artículo se encuentra disponible en la siguiente URL: https://revista.profesionaldelainformacion.com/index.php/EPI/article/view/86449 Este artículo pertenece al número "Interacción y visualización ". Las enfermedades raras son patologías muy severas y discapacitantes que afectan al 7% de la población mundial. Para intentar visibilizar y denunciar su situación, las personas que padecen estas enfermedades y sus familias hallaron en Facebook, Twitter y YouTube, entre otras redes sociales, un canal eficaz para compartir sus problemas, exigir una mayor inversión en investigación y poder conllevar sus dificultades diarias. Desde entonces, se han estimado como válidos elementos simbólicos y d…

Multilocus phylogenetics of smooth clam shrimps (Branchiopoda, Laevicaudata)

2021

International audience; Laevicaudatan branchiopods, also called ‘smooth clam shrimps’ or ’pea shrimps’, are rare crustaceans found exclusively in temporary, small freshwater bodies, which stay dry most of the year. Only 42 laevicaudatan species have been described so far, 90% of which belong to the genus Lynceus. The first multilocus phylogeny of the group is provided here, based on 15 Lynceus species from North and South America, Europe, Africa, Asia, Australia and New Caledonia and using nine molecular markers (two mitochondrial and seven nuclear genes, including newly designed primers). Genetic data suggest populations of Lynceus brachyurus from Europe and North America to represent a co…

Retour sur la crise de l’euro (2008-2018) : 10 ans après, le malade est-il guéri ? L’image du corps et de la maladie dans le discours économique de m…

2021

Occurrence of selected per- and polyfluorinated alkyl substances (PFASs) in food available on the European market - A review on levels and human expo…

2021

Abstract Per- and polyfluorinated alkyl substances (PFASs) are considered emerging persistent organic pollutants, which are chemically, thermally, and biologically stable, or degrade to persistent end products. Dietary intake is considered as one of the main human exposure pathways of these chemicals and, having entered the human body, PFASs are not metabolised and accumulate in tissues, while their toxicological properties may cause various health problems. Several studies on the occurrence of PFASs in various food types have been conducted, including the assessment of dietary exposure. The most important sources were fish, meat, eggs, fruits, and vegetables. Fruits and vegetables recently…

Air Pollution Research Based on Spider Web and Parallel Continuous Particulate Monitoring—A Comparison Study Coupled with Identification of Sources

2021

Air pollution is monitored mainly in urban or industrial areas, even if it is known that in rural ones, low emission can significantly worsen air quality. Hence, cheap and easily accessible methods of monitoring are needed. Recently, spider webs biomonitoring is getting popular, however, there is no information about its comparison with active methods. In this study, PTEs accumulated on spider webs were compared with results from continuous particulate monitor (CPM). Generally, higher potentially toxic elements concentrations were noted in spider web, with exception in the case of Zn. Zn may be present rather in smaller fractions, hence it needs more time for accumulation on spider web whil…

false

2021

The microbiota impacts mesenteric ischemia-reperfusion injury, aggravating the interaction of leukocytes with endothelial cells in mesenteric venules. The role of defined gut microbiomes in this life-threatening pathology is unknown. To investigate how a defined model microbiome affects the adhesion of leukocytes in mesenteric ischemia-reperfusion, we took advantage of gnotobiotic isolator technology and transferred altered Schaedler flora (ASF) from C3H/HeNTac to germ-free C57BL/6J mice. We were able to detect all eight bacterial taxa of ASF in fecal samples of colonized C57BL/6J mice by PCR. Applying qRT-PCR for quantification of species-specific 16S rDNA sequences of ASF bacteria, we fou…

Building-up host-guest helicate motifs and chains: a magneto-structural study of new field-induced cobalt-based single-ion magnets.

2021

In this work, we present the synthetic pathway, a refined structural description, complete solid-state characterization and the magnetic properties of four new cobalt(II) compounds of formulas [Co(H2O)6][Co2(H2mpba)3]·2H2O·0.5dmso (1), [Co(H2O)6][Co2(H2mpba)3]·3H2O·0.5dpss (2), [Co2(H2mpba)2(H2O)4]n·4nH2O (3), and [Co2(H2mpba)2(CH3OH)2(H2O)2]n·0.5nH2O·2ndpss (4) [dpss = 2,2′-dipyridyldisulfide and H4mpba = 1,3-phenylenebis(oxamic) acid], where 2 and 4 were obtained from [Co(dpss)Cl2] (Pre-I) as the source of cobalt(II). All four compounds are air-stable and were prepared under ambient conditions. 1 and 2 were obtained from a slow diffusion method [cobalt(II) : H2mpba2− molar ratio used 1 : …

Towards a learning community: understanding teachers’ mental models to support their professional development and learning

2021

Amidst societal, demographic and educational changes, teachers are expected to engage in professional development and learning (PDL) throughout their careers. This study explores school teachers’ mental models about their work in the framework of Senge’s learning organisation, aiming to support their PDL during curriculum reform and organisational changes. The study’s data comprise 41 semi-structured interviews with each teacher in one school community. These interviews were analysed using qualitative, data-driven yet theory-informed content analysis. In the first analysis phase, fragments of mental models concerning teachers’ work and their school community were explored. These fragments i…

Multiplicities of fields of values of irreducible characters of finite groups

2021

We show that if f f is the largest multiplicity of the fields of values of the irreducible characters of a finite group G G , then | G | |G| is bounded from above in terms of f f .

Waste not, want not: Report of a completely calcified C1-C2 juxtafacet cyst and literature review

2021

Background: Calcified juxtafacet cysts in the cervical spine are extremely rate. Such symptomatic cysts commonly cause neck pain, radiculopathy, or even myelopathy. MR and CT studies typically document cord/ root compression. On occasion, some of these cysts will spontaneously regress, while many others may warrant surgical removal. Case Description: A 70-year-old male presented with a 2-year history of a progressive tetraparesis. The preoperative MR/CT studies showed a C1-C2 left extradural mass occupying more than half of the spinal canal. On MR, it was homogeneously hypointense on both T1- and T2-weighted images, while the CT showed a calcified cyst. Intraoperative and histopathological…

false

2021

Background Health literacy is a concept that refers to patients’ ability to manage their disease and the health system’s ability to guarantee access to services. There is evidence that health literacy impacts the health outcomes of patients with chronic diseases, but detailed information on this topic in patients with liver cirrhosis is scarce. It was the aim of this study to identify risk factors for poorer health literacy in patients with liver cirrhosis. Methods 89 patients with liver cirrhosis were enrolled in this study and health literacy was measured using the Health Literacy Questionnaire (HLQ). Covert hepatic encephalopathy (CHE) was diagnosed clinically according to the West-Have…