showing 36 of ~574560 from 574555 documents

Online interventions to prevent mental health problems implemented in school settings: the perspectives from key stakeholders in Austria and Spain

2021

Abstract Background Schools are key settings for delivering mental illness prevention in adolescents. Data on stakeholders’ attitudes and factors relevant for the implementation of Internet-based prevention programmes are scarce. Methods Stakeholders in the school setting from Austria and Spain were consulted. Potential facilitators (e.g. teachers and school psychologists) completed an online questionnaire (N=50), policy makers (e.g. representatives of the ministry of education and health professional associations) participated in semi-structured interviews (N=9) and pupils (N=29, 14–19 years) participated in focus groups. Thematic analysis was used to identify experiences with, attitudes a…

safetyAdolescentpsychologistsPsychological interventionComputer-assisted web interviewingpupilhealth personnelprivacy03 medical and health sciences0302 clinical medicinepreventionHumansAcademicSubjects/MED00860AcademicSubjects/SOC01210030212 general & internal medicineadolescentsCurriculumschool (environment)School Health ServicesMedical educationInternetSchoolsteachersPart II: ICare Stakeholder SurveySchool psychologyPublic Health Environmental and Occupational HealthStakeholderFocus groupMental healthprevention programInternet-based intervention030227 psychiatrymental disordersMental HealthSpainattitudeAustriaThematic analysisPsychologyAcademicSubjects/SOC02610Internet-Based Interventionmental health

Characterization and Stage-Dependent Lineage Analysis of Intermediate Progenitors of Cortical GABAergic Interneurons

2021

Intermediate progenitors of both excitatory and inhibitory neurons, which can replenish neurons in the adult brain, were recently identified. However, the generation of intermediate progenitors of GABAergic inhibitory neurons (IPGNs) has not been studied in detail. Here, we characterized the spatiotemporal distribution of IPGNs in mouse cerebral cortex. IPGNs generated neurons during both embryonic and postnatal stages, but the embryonic IPGNs were more proliferative. Our lineage tracing analyses showed that the embryonically proliferating IPGNs tended to localize to the superficial layers rather than the deep cortical layers at 3 weeks after birth. We also found that embryonic IPGNs derive…

0301 basic medicineLineage (genetic)Ganglionic eminencelaminar distributionNeurosciences. Biological psychiatry. NeuropsychiatryBiologyInhibitory postsynaptic potential03 medical and health sciences0302 clinical medicinemedicinecortical developmentGABAergic neuron progenitorsProgenitor cellOriginal ResearchGeneral NeuroscienceEmbryonic stem cellCell biology030104 developmental biologymedicine.anatomical_structureCerebral cortexExcitatory postsynaptic potentialGABAergicfate analysis030217 neurology & neurosurgeryNeurosciencelineageRC321-571Frontiers in Neuroscience

Ethnobotany of the Aegadian Islands: safeguarding biocultural refugia in the Mediterranean

2021

Abstract Background The Aegadian Islands are located west of Trapani, Sicily. Once the site of bountiful tuna fisheries and fruit orchards (plums, peaches, apricots), grapevines, prickly pears, and grains, the local economy is now based on tourism, and many traditional agricultural and maritime practices have been abandoned. In this study, we aimed to evaluate the state of traditional ecological knowledge (TEK) concerning the use of wild and cultivated plants and fungi for human health, food, maritime, and agricultural purposes on the islands of Levanzo, Favignana, and Marettimo and compare present-day practices with those documented in the past. Methods In-depth semi-structured interviews …

0106 biological sciencesCultural StudiesThe MediterraneanFloraHealth (social science)Artemisia arborescensBiocultural diversityPopulationBiodiversityEthnobotanyPleurotus01 natural sciencesPleurotus eryngiiOther systems of medicineAgave sisalana; Artemisia arborescens; Glaucium flavum; Medicinal plants; Pleurotus eryngii; Ruta chalepensis; The MediterraneanAgaveMedicinal plantsPapaveraceaeHumansTraditional knowledgeeducationAgave sisalanaSicilyIslandseducation.field_of_studyCultivated plant taxonomyPlants MedicinalAgroforestrySettore BIO/02 - Botanica SistematicaResearchBotanyRuta chalepensisGlaucium flavum0104 chemical sciences010404 medicinal & biomolecular chemistryGeographyHerbariumKnowledgeComplementary and alternative medicineArtemisiaRefugiumAgave sisalana Artemisia arborescens Glaucium flavum Medicinal plants Pleurotus eryngii Ruta chalepensis The MediterraneanEthnobotanyQK1-989General Agricultural and Biological SciencesRZ201-999010606 plant biology & botanyJournal of Ethnobiology and Ethnomedicine

Cardiovascular system in the sars-CoV-2: impact of therapies.

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Physiologybusiness.industrySARS-CoV-2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)COVID-19VirologyCardiovascular SystemCardiovascular DiseasesInternal MedicineMedicineHumansCardiology and Cardiovascular MedicinebusinessJournal of hypertension

A review of hydropower plants in Romania: Distribution, current knowledge, and their effects on fish in headwater streams

2021

Abstract Hydropower is currently experiencing a boom in southeast Europe. For Romania, the number of hydropower plants is estimated to be between 545 and 674, but little has been published about their environmental impact. We provide the first overview of the geographical distribution of hydropower plants in Romania, supplemented by a review of current knowledge about their environmental impact, and present case study evidence on the effects of small hydropower plants on fish in headwater streams of the Carpathian Mountains. We show that 49% of the documented 545 hydropower plants in Romania are located in Natura 2000 or other protected areas, 5% are located in water bodies with ‘very good’…

Small hydroRenewable Energy Sustainability and the Environmentbusiness.industry020209 energyBiodiversity02 engineering and technologySTREAMSWater Framework DirectiveEnvironmental protectionEnvironmental monitoring0202 electrical engineering electronic engineering information engineeringEnvironmental scienceEnvironmental impact assessmentbusinessNatura 2000HydropowerRenewable and Sustainable Energy Reviews

P–231 Transnational oocyte donation program between Italy and Spain based on transport of vitrified oocytes: a five-years experience

2021

Abstract Study question What is the clinical efficacy of an oocyte donation program based on the transportation of vitrified oocytes between two countries? Summary answer The transnational oocyte donation program is efficient, safe and comparable to other strategies (transport of frozen sperm and embryos). What is known already Egg donation represents a valid treatment strategy for women who have exhausted their ovarian function and it has considerably increased in the last years. In Italy, egg donation is allowed after the judgment of the Constitutional Court n. 162 in 2014 but no reimbursement for the donors is provided. For this reason, the number of voluntary donors is irrelevant. There…

Pregnancybusiness.industrymedicine.medical_treatmentRehabilitationObstetrics and GynecologyEmbryomedicine.diseaseCryopreservationEmbryo transferAndrologyPregnancy rateHuman fertilizationReproductive MedicinemedicineCardiopulmonary resuscitationbusinessSurvival rateHuman Reproduction

Trayectoria, obra y cultura pedagógica de Antonio Ballesteros Usano

2021

Antonio Ballesteros Usano fue un notable maestro que ejerció una brillante actividad durante más de medio siglo en España y México. En España como inspector de enseñanza y divulgador de la renovación educativa, y en suelo mexicano, a donde llegó en 1939 huyendo del franquismo, como escritor y formador de normalistas y pedagogos. Este trabajo reconstruye por primera vez su trayectoria de manera integral al aplicar la metodología histórico-educativa y emplear fuentes primarias inéditas. Aporta datos novedosos, corrige inexactitudes y analiza los referentes ideológicos y pedagógicos que orientaron su actuación. Entre las conclusiones destacan los fuertes vínculos que le unieron al movimiento d…

media_common.quotation_subjectIdeologySociologyEducacióHumanitiesEducationmedia_commonPerfiles Educativos

Nuclear performances of the water-cooled lithium lead DEMO reactor: Neutronic analysis on a fully heterogeneous model

2021

Abstract The development of a conceptual design for the Demonstration Fusion Power Reactor (DEMO) is a key issue within the EUROfusion roadmap. The DEMO reactor is designed to produce a fusion power of about 2 GW and generate a substantial amount of electricity, relying on a closed tritium fuel cycle: it implies that the breeding blanket (BB) shall guarantee a suitable tritium production to enable a continuous operation without any external supply. The Water-Cooled Lithium Lead (WCLL) concept is a candidate for the DEMO BB: it uses liquid Lithium Lead as breeder and neutron multiplier and water in PWR condition as coolant. The neutronics analyses carried out in the past have been performed …

Neutron transportTokamakBreeding blanket;Computer scienceNuclear engineeringBlanket01 natural sciences010305 fluids & plasmaslaw.inventionBreeder (animal)Conceptual designlaw0103 physical sciencesMCNPNeutronicsGeneral Materials ScienceNeutron010306 general physicsDEMOCivil and Structural EngineeringMechanical EngineeringFusion powerWCLLCoolantNuclear Energy and EngineeringNuclear analysisBreeding blanketFusion Engineering and Design

Relationship between Training Load Management and Immunoglobulin A to Avoid Immunosuppression after Soccer Training and Competition: A Theoretical Fr…

2021

Immunoglobulin A (IgA), which is the main effector against upper respiratory tract viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been related to training load management. The aim of this systematic review was to establish the relationship between training load and salivary IgA based on current evidence in order to avoid immunosuppression after exercise and players´ vulnerability to virus contagion. A systematic review of relevant articles was carried out using two electronic databases (PubMed and Web of Science) until 19 May 2021. From a total of 127 studies initially found, 23 were included in the qualitative synthesis. These studies were clustered depen…

Immunoglobulin Amedicine.medical_specialtyLeadership and Managementmedicine.medical_treatmentHealth Informaticsimmunology03 medical and health sciences0302 clinical medicineHealth Information ManagementHealth caremedicine030212 general & internal medicineTreadmillbiologySARS-CoV-2business.industryAthletespandemicHealth PolicyRTraining (meteorology)Immunosuppression030229 sport sciencesmedicine.diseasebiology.organism_classificationUpper respiratory tract infectionupper respiratory tract infectionSprintPhysical therapybiology.proteinMedicineSystematic ReviewbusinessIgAHealthcare

Stakeholders? views on online interventions to prevent common mental health disorders in adults implemented into existing healthcare systems in Europe

2021

Abstract Background Online preventive interventions can help to reduce the incidence of mental disorders. Whereas knowledge on stakeholders’ attitudes and factors relevant for successfully integrating online treatment into existing healthcare systems is available, knowledge is scarce for online prevention. Methods Stakeholders from Germany, Switzerland, Austria and Spain were surveyed. Potential facilitators/delivery staff (e.g. psychologists, psychotherapists) completed an online questionnaire (n = 183), policy makers (i.e. from the governing sector or health insurance providers) participated in semi-structured interviews (n = 16) and target groups/potential users of mental illness prevent…

AdultpsychologistsPsychological intervention610 Medicine & healthComputer-assisted web interviewing03 medical and health sciences0302 clinical medicinepreventionGermanymedicineHumansAcademicSubjects/MED00860AcademicSubjects/SOC01210030212 general & internal medicine610 Medicine & healthQualitative ResearchMedical educationbusiness.industryPart II: ICare Stakeholder SurveyMental DisordersadultPublic Health Environmental and Occupational HealthUsabilityhealth care systemsMental illnessmedicine.diseaseFocus groupMental healthInternet-based interventionmental disordersEuropeMental HealthSpainattitudeAustriaThematic analysisPsychologybusinessAcademicSubjects/SOC02610Delivery of Health Care030217 neurology & neurosurgeryInternet-Based Interventionmental healthHealthcare system

Mechanical rotational thrombectomy in long femoropopliteal artery and stent occlusion in COVID-19 patient: Case report

2021

Abstract Introduction Coronavirus disease-19 (COVID-19) has been increasingly associated with thromboembolic complications. COVID-19 infection has a thrombogenic potential for stents. Herein, we report a case of stent thrombosis in diabetic obese patient COVID-19 positive where was previously released a Multilayer Flow Modulator stent (MFM) for large popliteal aneurysm. Case report A 78-year-old male was referred to our hospital for fever and acute pain in the left leg. At history, the same patient had endovascular procedure for a large symptomatic popliteal aneurysm, treated through release of three MFM. The pulmonary CT scan showed COVID-19 infection with confirm of rhino-laryngeal swab. …

medicine.medical_specialtymedicine.medical_treatmentCase ReportRevascularizationSettore MED/22 - Chirurgia VascolarePopliteal aneurysm03 medical and health sciences0302 clinical medicinemedicineMultilayer Flow Modulator stentAcute limb ischemiacardiovascular diseasesbusiness.industryCOVID-19Stentequipment and suppliesDebulkingmedicine.diseaseArterial occlusionThrombosisSurgeryCathetersurgical procedures operativemedicine.anatomical_structure030220 oncology & carcinogenesisRotarex030211 gastroenterology & hepatologySurgeryMechanical thrombectomybusinessArteryInternational Journal of Surgery Case Reports

Time Deixis in Engineering Discourse

2021

Nowadays, it has become commonly accepted that the meaning of linguistic elements is interconnected with the context of their use. Deixis is one of the classical pragmatic phenomena that illustrates that context-dependence is inherent in language as meaning of deictic expressions cannot be constructed without the identification of the speech event where these expressions occurred. The present article discusses cases of time deixis in the context of engineering discourse. The goal of the research is to demonstrate how the deictic expression use in different genres of professional discourse impacts meaning construction. The study deals with the data obtained from scientific articles, encyclop…

pragmatic meaningengineering discoursetime deixisLiterature (General)P1-1091General MedicineSociologyDeixisreferencePN1-6790Philology. LinguisticsLinguisticsdeictic expressionsBaltic Journal of English Language, Literature and Culture

Do Saharan Dust Days Carry a Risk of Hospitalization From Respiratory Diseases for Citizens of the Canary Islands (Spain)?

2021

Background: Saharan dust meets the Canary Islands at the beginning of its westward path across the North Atlantic, exceeding the European daily levels for PM10; for this reason, their two provincial capital cities, constitute optimal sites where to evaluate the health effects of this natural event. Objectives: To assess the short-term association between Saharan Dust Days (SDDs) and respiratory morbidity in the two capital cities. Methods: We carried out a time-series analysis with daily emergency hospital admissions due to all respiratory system diseases, chronic obstructive pulmonary disease (COPD) and asthma between 2001 and 2005, assessing the independent effect of SDDs, defined accordi…

Pulmonary and Respiratory MedicineSeries temporalesRespiratory diseasesSaharan dustProvincial capitalGeneralized additive modelPulmonary diseaseCalima saharianaMineral dustIngresos hospitalariosPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicineAir PollutionEnvironmental healthRespiratory morbiditymedicineHumansAfrican air intrusionsRespiratory systemAsthmaHospital admissionsAir PollutantsCOPDbusiness.industryDustGeneral MedicineIntrusiones de aire africanoRespiration Disordersmedicine.diseaseModelos aditivos generalizadosAsthmaConfidence intervalPartículas en suspensiónHospitalizationEnfermedades respiratorias030228 respiratory systemSpainParticulate MatterTime-seriesbusinessParticulate matter

New high-sensitivity searches for neutrons converting into antineutrons and/or sterile neutrons at the HIBEAM/NNBAR experiment at the European Spalla…

2021

Abstract The violation of baryon number, B , is an essential ingredient for the preferential creation of matter over antimatter needed to account for the observed baryon asymmetry in the Universe. However, such a process has yet to be experimentally observed. The HIBEAM/NNBAR program is a proposed two-stage experiment at the European Spallation Source to search for baryon number violation. The program will include high-sensitivity searches for processes that violate baryon number by one or two units: free neutron–antineutron oscillation ( n → n ̄ ) via mixing, neutron–antineutron oscillation via regeneration from a sterile neutron state ( n → [ n ′ , n ̄ ′ ] → n ̄ ), and neutron disappearan…

baryon number violation; feebly interacting particles; European Spallation Source; baryogenesisPhysics beyond the Standard ModelNuclear TheoryEXPERIMENTAL LIMITfeebly interacting particlesbaryogenesisAntineutron01 natural sciencesSubatomär fysikANTIPROTON ANNIHILATIONn: oscillationSubatomic Physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentsterilePhysicsMIRROR MATTERnew physicsanti-nddc:Antimatterbaryon: asymmetryproposed experimentDAMA ANNUAL MODULATIONNuclear and High Energy PhysicsParticle physicsAccelerator Physics and Instrumentation114 Physical sciencesBaryon asymmetrynuclear physics0103 physical sciencesDARK-MATTERmixingNeutronSensitivity (control systems)[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]TRANSITION OPERATORS010306 general physicsbaryon number: violationactivity report010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyAcceleratorfysik och instrumenteringMAJORANA NEUTRINOSsensitivitybaryon number violationBaryogenesisregenerationEuropean Spallation SourceUNIFIED PICTUREB-L SYMMETRYBaryon numberBARYON-NUMBER NONCONSERVATION

Bibliometric analysis of the scientific production of literature on peri-implant diseases in the Web of Science.

2021

Background The exponential increase in implant placement worldwide and the high prevalence of its associated pathologies have prompted an increasing contribution by the scientific community to the number of publications related to peri-implant pathologies. Purpose The objective of this work is to carry out a bibliometric analysis of scientific production on peri-implant diseases. Materials and methods The search strategy included titles, keywords, and abstracts based on the term peri-implantitis and all the possible combinations existing in Science Citation Index Expanded (SCIE) of the main collection of Web of Science. Two limits were established: the document typology was limited to Artic…

TypologyDental ImplantsBibliometric analysisHigh prevalenceScientific productionScience Citation IndexLibrary scienceScientific literaturePeri-ImplantitisWork (electrical)BibliometricsPolitical sciencePrevalenceHumansOral SurgeryGeneral DentistryTypographical errorClinical implant dentistry and related researchREFERENCES

Uomini e alberi. Tre indagini storico-religiose. Nota introduttiva

2021

In this introductory note I present three essays on the relationship between trees and rituals in ancient Mediterranean civilisations and in Vedic India.

Settore L-ANT/02 - Storia Grecaancient Mediterranean Vedic India trees ritualsSettore M-STO/06 - Storia Delle Religioni

Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.

2021

Citrulline malate (CitMal) is a dietary supplement that is suggested to enhance strength training performance. However, there is conflicting evidence on this matter. Thus, the purpose of this meta-analysis was to determine whether supplementing with CitMal prior to strength training could increase the total number of repetitions performed before reaching voluntary muscular failure. A systematic search was conducted wherein the inclusion criteria were double-blind, placebo-controlled studies in healthy participants that examined the effect of CitMal on repetitions to failure during upper body and lower body resistance exercises. The Hedges’s g standardized mean differences (SMD) between the …

AdultMalemedicine.medical_specialtyTime FactorsStrength trainingCitrulline malateDietary supplementMalatesMedicine (miscellaneous)Acute effectPerformance-Enhancing SubstancesPlacebo03 medical and health sciencesYoung Adult0302 clinical medicineBiasDouble-Blind MethodMedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineRandomized Controlled Trials as TopicNutrition and Dieteticsbusiness.industryUpper bodyResistance Training030229 sport sciencesGeneral MedicinePhysical Functional PerformanceCurrent analysisMeta-analysisPhysical therapyPhysical EnduranceCitrullineFemalebusinessInternational journal of sport nutrition and exercise metabolism

Innovative sports-embedded gambling promotion: A study of spectators’ enjoyment and gambling intention during XFL games

2021

Abstract The sports industry has continued to grow on the basis of innovative practices. One such recent innovation in sport was the introduction of live on-screen betting odds during XFL game broadcasts. Such a service had never before been offered in the United States. This paper examines the impact of these live on-screen betting odds on fan engagement and consumer experience (increased spectator enjoyment and gambling intention) during the XFL season. Fuzzy-set qualitative comparative analysis reveals interesting results. For both increased spectator enjoyment and high levels of gambling intention, the combination of high levels of perceived enjoyment, excitement expectancy, and escape …

MarketingExpectancy theoryService (business)Qualitative comparative analysismedia_common.quotation_subject05 social sciencesOddsConsumer experiencePower (social and political)Promotion (rank)0502 economics and business050211 marketingPsychologySocial psychology050203 business & managementmedia_common

Annexe" Logement social", in Code des baux, sous la dir.J.Lafond

2021

International audience

[SHS] Humanities and Social SciencesComputingMilieux_MISCELLANEOUS[SHS]Humanities and Social Sciences

Comparison of Delivery Methods in Phage Therapy against Flavobacterium columnare Infections in Rainbow Trout

2021

Viruses of bacteria, bacteriophages, specifically infect their bacterial hosts with minimal effects on the surrounding microbiota. They have the potential to be used in the prevention and treatment of bacterial infections, including in the field of food production. In aquaculture settings, disease-causing bacteria are often transmitted through the water body, providing several applications for phage-based targeting of pathogens, in the rearing environment, and in the fish. We tested delivery of phages by different methods (via baths, in phage-coated material, and via oral delivery in feed) to prevent and treat Flavobacterium columnare infections in rainbow trout fry using three phages (FCOV…

Microbiology (medical)Microbiological culturebakteeritauditphage therapyPhage therapymedicine.medical_treatmentVirulenceRM1-950BiologyBiochemistryMicrobiologyArticlebakteriofagitMicrobiologybakteeritBacteriophage03 medical and health sciencesFlavobacterium columnareAquaculturebacteriophagehoitomenetelmätmedicinePharmacology (medical)General Pharmacology Toxicology and Pharmaceuticsvesiviljely (kalatalous)030304 developmental biology0303 health sciencestreatment030306 microbiologybusiness.industrylohikalatbacterial infectionbiology.organism_classification<i>Flavobacterium columnare</i>rainbow trout3. Good healthfagiterapiavirulenceInfectious Diseasesphage deliveryaquaculturecolumnaris diseaseFlavobacterium columnareRainbow troutTherapeutics. PharmacologybusinessBacteriaAntibiotics

Amplitude analysis and branching fraction measurement of Ds+→K−K+π+π0

2021

We report an amplitude analysis and branching fraction measurement of Ds+→K+K−π+ decay using a data sample of 3.19 fb−1 recorded with BESIII detector at a center-of-mass energy of 4.178 GeV. We perform a model-independent partial wave analysis in the low K+K− mass region to determine the K+K− S-wave line shape, followed by an amplitude analysis of our very pure high-statistics sample. With the detection efficiency based on the amplitude analysis results, the absolute branching fraction is measured to be B(Ds+→K+K−π+)=(5.47±0.08stat±0.13sys)%.

Physics010308 nuclear & particles physicsBranching fractionPartial wave analysisAnalytical chemistry01 natural sciencesNOSubatomär fysikAmplitudeSubatomic Physics0103 physical sciencesPiAtomic physics010306 general physicsLine (formation)Physical Review D

EPHA7 haploinsufficiency is associated with a neurodevelopmental disorder

2021

International audience; Ephrin receptor and their ligands, the ephrins, are widely expressed in the developing brain. They are implicated in several developmental processes that are crucial for brain development. Deletions in genes encoding for members of the Eph/ephrin receptor family were reported in several neurodevelopmental disorders. The ephrin receptor A7 gene (EPHA7) encodes a member of ephrin receptor subfamily of the protein-tyrosine kinase family. EPHA7 plays a role in corticogenesis processes, determines brain size and shape, and is involved in development of the central nervous system. One patient only was reported so far with a de novo deletion encompassing EPHA7 in 6q16.1. We…

MaleMicrocephaly[SDV]Life Sciences [q-bio]6q161 microdeletionInheritance PatternsEPHA7HaploinsufficiencyBiologyspeech and language developmentNeurodevelopmental disorderExome SequencingGeneticsmedicineEphrinHumansGenetic Predisposition to DiseasemicrocephalyGenetics (clinical)Genetic Association StudiesIn Situ Hybridization FluorescenceGeneticsComparative Genomic Hybridization6q16.1 microdeletionErythropoietin-producing hepatocellular (Eph) receptorReceptor EphA7medicine.diseasePenetrancePhenotypeneurodevelopmental disorderPedigree[SDV] Life Sciences [q-bio]PhenotypeNeurodevelopmental Disordersintellectual disabilityEPHA7MutationChromosomes Human Pair 6FemaleHaploinsufficiencyClinical Genetics

Smoking and Neuropsychiatric Disease-Associations and Underlying Mechanisms.

2021

Despite extensive efforts to combat cigarette smoking/tobacco use, it still remains a leading cause of global morbidity and mortality, killing more than eight million people each year. While tobacco smoking is a major risk factor for non-communicable diseases related to the four main groups—cardiovascular disease, cancer, chronic lung disease, and diabetes—its impact on neuropsychiatric risk is rather elusive. The aim of this review article is to emphasize the importance of smoking as a potential risk factor for neuropsychiatric disease and to identify central pathophysiological mechanisms that may contribute to this relationship. There is strong evidence from epidemiological and experiment…

medicine.medical_specialtyneuropsychiatric disorder ; smoking ; smoking-induced disease ; inflammation ; oxidative stressQH301-705.5DiseaseReviewCatalysisInorganic Chemistry03 medical and health sciences0302 clinical medicineRisk FactorsEpidemiologymedicineTobacco SmokingDementiaAnimalsHumans030212 general & internal medicinePhysical and Theoretical ChemistryCognitive declineRisk factorBiology (General)PsychiatryMolecular BiologyQD1-999SpectroscopyDepression (differential diagnoses)business.industryOrganic ChemistrySmokingsmoking-induced diseaseneuropsychiatric disorderGeneral Medicinemedicine.diseaseAnxiety DisordersComputer Science ApplicationsChemistryOxidative StressSchizophreniainflammationbusiness030217 neurology & neurosurgeryAnxiety disorderSignal TransductionInternational journal of molecular sciences

María José Báguena Cervellera (1956-2021) : In Memoriam

2021

María José Báguena Cervellera, profesora e investigadora de historia de la medicina en el Departamento de Historia de la Ciencia y Documentación de la Universidad de València. Su investigación se centró en el estudio de los inicios de la teoría del contagio animado como explicación causal de las enfermedades infecciosas a través de la asimilación en España de los trabajos de las escuelas bacteriológicas francesa y alemana. También estudió la evolución histórica de algunas enfermedades infecciosas como el cólera, la rabia, la tuberculosis, la viruela, la poliomielitis, el sarampión y la rubéola, además de interesarse por la historia de la medicina valenciana contemporánea

Dones en la medicinaMedicina InvestigacióHistory and Philosophy of ScienceMedicina EnsenyamentGeneral Medicine

O-142 COVID19-free endometrium: Undetectable viral RNA in endometrial biopsies from positive symptomatic SARS-CoV-2 women

2021

Abstract Study question Does SARS-CoV-2 infect the endometrial tissue in women with coronavirus disease 2019 (COVID-19)? Summary answer Symptomatic women with COVID-19 report no presence, in the short term, of viral RNA from SARS-CoV-2 in the endometrium. What is known already The recent emergence of COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has not allowed yet to establish putative relations between this disorder and other existing pathologies. It is the case with fertility problems and the reproductive organs, including a possible endometrial disorder caused by the virus. Thus, an important step is to elucidate the viral presence in different hu…

2019-20 coronavirus outbreakmedicine.anatomical_structureReproductive MedicineCoronavirus disease 2019 (COVID-19)business.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)RehabilitationmedicineObstetrics and GynecologyViral rnaEndometriumbusinessVirologyHuman Reproduction

Implications of terrain resolution on modeling rainfall-triggered landslides using a TIN- based model

2021

Abstract This study employs a distributed eco-hydrological-landslide model, the tRIBS-VEGGIE-Landslide, to evaluate the influence of terrain resolution on the hydro-geomorphological processes involved in slope stability analysis. The model implements a Triangulated Irregular Network (TIN) to describe the topography starting from a grid-DEM. Five grid-DEM resolutions of the case study basin, i.e., 10, 20, 30 and 70 m, are used to derive the corresponding TINs. The results show that using irregular meshes reduces the loss of accuracy with coarser resolutions in the derived slope distribution in comparison to slope distributions estimated from the original grid-based DEM. From a hydrological p…

Environmental EngineeringSlope stability analysisEcological ModelingHydrological modellingSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaResolution (electron density)TerrainLandslideSoil scienceHydrologic modelingTriangulated irregular networkDigital elevation modelsSlope stabilityNumerical modelingDigital elevation models; Hydrologic modeling; Landslides; Numerical modeling; Slope stability analysisDigital elevation models Hydrologic modeling Landslides Numerical modeling Slope stability analysisDigital elevation modelSlope stability analysisLandslidesSoftwareGeologyEnvironmental Modelling &amp; Software

Physical function and frailty in elderly patients with acute coronary syndrome

2021

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): This work was supported by grants from CIBER CV, Madrid, Spain [grant number 16/11/00420] and Instituto de Salud Carlos III-FEDER, Madrid, Spain. Background Frailty is described a complex clinical syndrome of increased vulnerability to stressors that places the individual at increased risk of adverse health outcomes. It results from multiple impairments (among others, in physical functioning) and its severity ranges from mild to severe. In older cardiac patients, frailty is reported to be a significant and an independent predictor of functional decline. Purpose To analy…

Advanced and Specialized Nursingmedicine.medical_specialtyAcute coronary syndromeEmotional vulnerabilitybusiness.industryStressorShort Physical Performance BatteryPhysical functionHealth outcomesmedicine.diseaseMedical–Surgical NursingPhysical therapyMedicineFrail elderlyCardiology and Cardiovascular MedicinebusinessEuropean Journal of Cardiovascular Nursing

false

2021

Although professional agency has become an increasingly crucial issue in work organizations, investigators lack a brief instrument to measure it. This paper introduces a short measure to explore professional agency at work. Our aim was to shorten the original 17-item Professional Agency Measure, while also exploring its usability for cross-validating questionnaire datasets, and investigating the relationship between professional agency and work engagement. Three dimensions of professional agency emerged, with three items per dimension, across the domains of healthcare, real estate services, and information technology (all within Finland). All the dimensions (Influencing at work, Participati…

Organizational Behavior and Human Resource Managementbusiness.industryWork engagementmedia_common.quotation_subjectPublic Health Environmental and Occupational HealthInformation technologyReal estateContext (language use)UsabilityPublic relationsNegotiationWork (electrical)Industrial relationsAgency (sociology)Life-span and Life-course StudiesbusinessPsychologymedia_commonNordic Journal of Working Life Studies

Pursuing decentralisation : regional cultural policies in Finland and Sweden

2021

In both Finland and Sweden, decentralisation has traditionally been an essential cultural policy aim. This article explores how, by pursuing decentralisation, the regional jurisdictions have been presented with more possibilities to fulfil their purposes and in this way, gain legitimacy in cultural policy. Based on the analysis of political, legal, and administrative documents, three main periods of regional decentralisation in cultural policies are identified: regions as vehicles of welfare policy, regionalisation, and competitive regions. In both countries, national governments have promoted the regional level’s agency, and in doing so, potential institutional change in cultural policy. H…

Cultural StudiesSwedenEconomic growthregional cultural policyhajautusSociology and Political SciencekulttuuripolitiikkahyvinvointipolitiikkadecentralisationalueellistaminenTvärvetenskapliga studier inom samhällsvetenskapDecentralizationkulttuuripalvelutkulttuuriPolitical scienceyhteiskuntapolitiikkaaluekehitysSocial Sciences InterdisciplinaryFinlandaluepolitiikka

Clinical Evolution and Quality of Life in Clinically Based COPD Chronic Bronchitic and Emphysematous Phenotypes: Results from the 1-Year Follow-Up of…

2021

Francesco Blasi, 1, 2 Raffaele Antonelli Incalzi, 3 Giorgio Walter Canonica, 4 Pietro Schino, 5 Giuseppina Cuttitta, 6 Alessandro Zullo, 7 Alessandra Ori, 7 Nicola Scichilone 8 On behalf of STORICO study group 1Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS C&agrave; Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, 20122, Italy; 3University Biomedical Campus of Rome, Rome, 00128, Italy; 4Personalized Medicine Asthma &amp; Allergy Clinic Humanitas University Humanitas research Hospital Rozzano, Rozzano (Milan), 20089, Italy; 5Miulli Hospital, Acquaviva …

Chronic bronchitismedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato RespiratorioDiseases of the respiratory systemPulmonary Disease Chronic ObstructiveClinical evolution Clinical phenotype COPD Quality of life Follow-Up Studies Humans Phenotype Quality of Life Bronchitis Chronic Emphysema Pulmonary Disease Chronic Obstructive ItalyQuality of lifeDLCOInternal medicinemedicineHumansCOPDDepression (differential diagnoses)Original ResearchEmphysemaclinical evolutionCOPDRC705-779business.industryMinimal clinically important differenceGeneral Medicineclinical phenotypemedicine.diseaseBronchitis ChronicPulmonologyPhenotypeItalyquality of lifeAnxietymedicine.symptombusinessFollow-Up StudiesInternational journal of chronic obstructive pulmonary disease

Profili istituzionali e pratiche in rete: il caso studio dei profili social della Regione Siciliana

2021

La diffusione dei social media, e l’impiego sempre più consistente da parte delle amministrazioni pubbliche (PA), ha messo in risalto alcune questioni relative alle dinamiche comunicative tra PA, cittadini e sistema dei media, imperniate su pochi ed essenziali concetti cardine, ossia la responsabilità, l’efficienza, la partecipazione, l’ascolto e la qualità. Negli ultimi anni tra le esigenze delle PA si è fatta avanti la necessità di essere presenti sui social e quindi di creare e alimentare dei profili social dedicati. La maggior parte delle regioni italiane è dotata di strutture di comunicazione (dipartimenti appositi, agenzie, società controllate o esterne) ed è presente sui principali s…

Settore SPS/08 - Sociologia Dei Processi Culturali E ComunicativiComunicazione pubblicapratiche in rete.social network

Towards a Critical Understanding of Social Networks for the Feminist Movement: Twitter and the Women’s Strike

2021

L'us intensiu de les plataformes digitals per part del moviment feminista ha sigut identificat com una de les seues caracteristiques claus en l'actualitat. Nombrosos estudis aborden l'us tactic de les xarxes socials per part d'aquest moviment, especialment el 8 de marc a Espanya. Aquest treball estudia els repertoris d'accio dels diferents actors que van participar en la conversa de la Vaga Feminista de 2019, tambe els comptes automatitzats. Els resultats empirics en demostren que Twitter no es un ambit exclusiu del moviment feminista. A mes de les activistes que hi van promoure i van informar sobre la Vaga Feminista, els partits politics van proposar mesures politiques concretes i les facc…

Feminist movementCommunicationPolitical scienceHumanitiesTripodos

Strategic planning for maxillofacial trauma and head and neck cancers during COVID-19 pandemic– December 2020 updated from Germany

2021

Strategic planning2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)business.industrySARS-CoV-2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINECOVID-19medicine.diseaseStrategic PlanningArticleOtorhinolaryngologyHead and Neck NeoplasmsGermanyPandemicMedicineHumansMaxillofacial InjuriesMedical emergencybusinessHead and neckPandemicsAmerican Journal of Otolaryngology

Autochthonous organic matter promotes DNRA and suppresses N2O production in sediments of the coastal Baltic Sea

2021

Coastal environments are nitrogen (N) removal hot spots, which regulate the amount of land-derived N reaching the open sea. However, mixing between freshwater and seawater creates gradients of inorganic N and bioavailable organic matter, which affect N cycling. In this study, we compare nitrate reduction processes between estuary and offshore archipelago environments in the coastal Baltic Sea. Denitrification rates were similar in both environments, despite lower nitrate and carbon concentrations in the offshore archipelago. However, DNRA (dissimilatory nitrate reduction to ammonium) rates were higher at the offshore archipelago stations, with a higher proportion of autochthonous carbon. Th…

liuennut orgaaninen hiili0106 biological sciencesAMMONIUM DNRADenitrification010504 meteorology & atmospheric sciencessedimentitOceanographyOXIDATION01 natural sciencesCARBONchemistry.chemical_compoundNitrateDOMTotal organic carbonchemistry.chemical_classificationdenitrificationgeography.geographical_feature_categorysediment organic matterN2ODENITRIFICATIONNitrogenDNRAEnvironmental chemistryArchipelagoorgaaninen ainesgeographic locationsdenitrifikaatiosuistotchemistry.chemical_elementDISSIMILATORY NITRATE REDUCTIONAquatic ScienceestuaryESTUARIESOrganic matter14. Life underwater1172 Environmental sciences0105 earth and related environmental sciencesgeography010604 marine biology & hydrobiologyEstuaryNITROUS-OXIDEPATHWAYSEstuaryN-2Sediment organic matterchemistrytypensidonta13. Climate actionEnvironmental scienceSeawaterrannikkovedet

Academia in cardiovascular radiology: are we doing enough for the future of the subspecialty?

2021

Aim To explore barriers to academic activities that cardiovascular radiology-oriented radiology trainees face worldwide. Materials and methods An international call for participation in an online survey was distributed via social media and radiological societies to radiology trainees. Questions covered barriers and involvement in academic activities during radiology training. Participants interested in cardiovascular radiology were selected for analysis with appropriate statistical methods. Results Of the 892 respondents, 120 (13.5%) reported an interest in cardiovascular imaging. The majority (63.3%, 76/120) were from Europe and 57.5% (69/120) were men. There were gender discrepancies in a…

AdultMalemedicine.medical_specialtyAcademic Medical CentersCareer Choicebusiness.industryInternship and ResidencyGeneral MedicineSubspecialtyCareer MobilityMentorshipWork (electrical)Cardiovascular DiseasesEducation Medical GraduateSurveys and QuestionnairesmedicineHumansRadiology Nuclear Medicine and imagingSocial mediaFemaleRadiologybusinessRadiologyClinical radiology

Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity

2021

Abstract Because of its wide spectrum of targets and biological activities, the oxazole ring is a valuable heterocyclic scaffold in the design of new therapeutic agents with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic and antidepressant properties. The presence of two heteroatoms, oxygen and nitrogen, offers possible interactions (hydrogen, hydrophobic, van der Waals or dipoles bonds) with a broad range of receptors and enzymes. Furthermore, the oxazole core conjugates low cytotoxicity with improved compound solubility and is well suited to structural modifications such as substitution with different groups and condensation to aromatic, heteroaroma…

chemistry.chemical_classificationColchicine binding inhibitorsbiologyChemistryAnti-Tubulin agentsHeteroatomRing (chemistry)Combinatorial chemistryRS1-441Other systems of medicinesymbols.namesakechemistry.chemical_compoundPharmacy and materia medicaEnzymeTubulinsymbolsbiology.proteinvan der Waals forceCytotoxicityOxazolesRZ201-999OxazoleConjugateCancer