showing 36 of ~574560 from 574555 documents
Educación XX1 : revista de la Facultad de Educación
2021
Resumen basado en el de la publicación Título, resumen y palabras clave en español y en inglés Se analizan los mecanismos empleados por la enseñanza católica española para afrontar la notabilísima reducción del profesorado religioso sufrida en las últimas décadas. Se trata de una cuestión inédita, abordada desde la perspectiva de la política de la educación y abarca desde la transición a la democracia hasta la actualidad. Se han localizado documentación y estadísticas escasamente conocidas, que han sido objeto de análisis documental mediante metodología mixta. Se contextualiza el proceso de secularización de la sociedad española y la consiguiente crisis de vocaciones. Posteriormente, se per…
Blastocyst formation is similar in obese and normal weight women: a morphokinetic study
2021
Abstract STUDY QUESTION Does the embryo cleavage pattern and rate of blastocyst formation differ between normal weight and obese women undergoing IVF? SUMMARY ANSWER Embryo morphokinetic development, final blastocyst formation rate and blastocyst morphology do not differ between obese and normal weight women. WHAT IS KNOWN ALREADY Female obesity has been related to impaired IVF outcomes. Although the mechanisms responsible for this detrimental effect are thought to include impaired oocyte and embryo quality and reduced endometrial receptivity, they are yet to be confirmed. Embryo quality has been commonly assessed using static morphological criteria. Only three studies have analysed the pro…
Diversification of diversity: Migrations, cultural pluralism and urban transformations in Palermo (Italy): a case study
2021
Italy experienced the transition from a country of emigration to a country of immigration only in the last decade of the 20th century. The extreme heterogeneity of the Italian scene – from the distribution and variety of productive sectors and local economic dimensions, to the geographical, cultural and linguistic varieties – results in an incredibly differentiated background on which the phenomenon of migrations fits as multiplier of diversity. But there are some particular fields in Italy where the challenges of superdiversity appear to be more prominent: the impact on the school system, in terms of linguistic-cultural pluralism; the change in religious belonging and identities; the dynam…
Expresivitatea limbajului popular în romanul haiducesc „Iancu Jianu, zapciu de plasă” și „Iancu Jianu, căpitan de haiduci” de Nicolae D. Popescu
2021
This paper analyzes the expressivity of popular language from the novels ”Iancu Jianu, Head of Administration” and ”Iancu Jianu, Captain of the Hajduks” by N.D. Popescu. The popular language is a language specific aspect, a language version and a main component of the oral version of the national language. In literary works, the popular language has a stylistic purpose. The aesthetic value of the text is the result of the process by which the expressiveness of the writer`s language is converted into an individual literary rule. The stylistic processes and brands encountered in popular language are national specific and they reflect the history, the way of thinking and the feelings of Romani…
Motives for gambling, cognitive distortions, and irresponsible gambling: Proposal for an explanatory model of gambling addiction in university studen…
2021
There are many factors that appear to be directly related to the development of gambling addiction problems, and it is important to understand these relationships from a clinical perspective in order to develop prevention and intervention programs. This research seeks to analyze the relationships these problems have with gambling motives, cognitive distortions and irresponsible gambling behavior, and proposes an explanatory model of gambling addiction. The sample was made up of 258 adults residing in the province of Valencia (59.5% women), with a mean age of 20.95 years (SD = 2.19). A series of questionnaires were applied to measure the variables involved, and bivariate correlations, simple…
Rethinking science communication in a changing landscape
2021
Science communication continues to grow, develop and change, as a practice and field of research. The boundaries between science and the rest of society are blurring. Digitalization transforms the public sphere. This JCOM special issue aims to rethink science communication in light of the changing science communication landscape. How to characterize the emerging science communication ecosystem in relation to the introduction of new media and actors involved? What new practices are emerging? How is the quality of science communication maintained or improved? We present a selection of papers that provide different perspectives on these questions and challenges.
Identification of Potential Distinguishing Markers for the Use of Cannabis-Based Medicines or Street Cannabis in Serum Samples
2021
Increasing prescription numbers of cannabis-based medicines raise the question of whether uptake of these medicines can be distinguished from recreational cannabis use. In this pilot study, serum cannabinoid profiles after use of cannabis-based medicines were investigated, in order to identify potential distinguishing markers. Serum samples after use of Sativex®, Dronabinol or medical cannabis were collected and analyzed for 18 different cannabinoids, using a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. Analytes included delta-9-tetrahydrocannabinol, 11-hydroxy-tetrahydrocannabinol, 11-nor-9-carboxy-tetrahydrocannabinol, cannabidiol, cannabinol, cannabigerol, …
Shedding Light on the Dark Ages: Sketching Potential Trade Relationships in Early Medieval Romania through Mitochondrial DNA Analysis of Sheep Remains
2021
Southeast Europe has played an important role in shaping the genetic diversity of sheep due to its proximity to the Danubian route of transport from the Near East into Europe, as well as its possible role as a post-domestication migration network and long tradition of sheep breeding. The history of Romania and, in particular, the historical province of Dobruja, located on the shore of the Black Sea, has been influenced by its geographical position at the intersection between the great powers of the Near East and mainland Europe, with the Middle Ages being an especially animated time in terms of trade, migration, and conflict. In this study, we analyzed the mitochondrial control region of fi…
SARS-CoV-2 RNA and antibody detection in human milk from a prospective multicenter study in Spain
2021
Background During the COVID-19 pandemic in 2020, breastfeeding in women positive for SARS-CoV-2 was compromised due to contradictory data regarding potential viral transmission. However, growing evidence confirms the relevant role of breast milk in providing passive immunity by generating and transmitting specific antibodies against the virus. Thus, our study aimed to develop and validate a specific protocol to detect SARS-CoV-2 in breast milk matrix as well as to determine the impact of maternal SARS-CoV-2 infection on presence, concentration, and persistence of specific SARS-CoV-2 antibodies. Study design/Methods A prospective multicenter longitudinal study in Spain was carried out from A…
Profiles of Frailty among Older People Users of a Home-Based Primary Care Service in an Urban Area of Barcelona (Spain): An Observational Study and C…
2021
Background: The multidimensional assessment of frailty allows stratifying it into degrees
false
2021
Ruthenium(II) polypyridine complexes are among the most popular sensitizers in photocatalysis, but they face some severe limitations concerning accessible excited-state energies and photostability that could hamper future applications. In this study, the borylation of heteroleptic ruthenium(II) cyanide complexes with alpha-diimine ancillary ligands is identified as a useful concept to elevate the energies of photoactive metal-to-ligand charge-transfer (MLCT) states and to obtain unusually photorobust compounds suitable for thermodynamically challenging energy transfer catalysis as well as oxidative and reductive photoredox catalysis. B(C6F5)(3) groups attached to the CN- ligands stabilize t…
Time-Restricted Feeding and Metabolic Outcomes in a Cohort of Italian Adults.
2021
Background: research exploring the effects of food timing and frequency on health and disease is currently ongoing. While there is an increasing body of scientific literature showing the potential health benefits of intermittent fasting (IF) in laboratory settings and in animals, studies regarding IF on humans are limited. Therefore, the objective of this research was to evaluate the relationship between the feeding/fasting time window and metabolic outcomes among adult individuals. Methods: dietary and demographic data of 1936 adult subjects living in the south of Italy were examined. Food frequency questionnaires (FFQ) were administered to determine the period of time between the first an…
Educación XX1 : revista de la Facultad de Educación
2021
Resumen basado en el de la publicación Título, resumen y palabras clave en español y en inglés El Trabajo Fin de Grado (TFG) se considera la experiencia de aprendizaje más relevante de un programa académico, de hecho, incluso se utiliza como indicador de la calidad del grado en su conjunto. Dada su relevancia, se analiza el planteamiento que realizan las universidades públicas y privadas en España de la asignatura de TFG de los grados en Maestro/a en Educación Infantil y/o Primaria, en Educación Social y en Pedagogía. Para alcanzar este objetivo se ha llevado a cabo un análisis de contenido de las 116 guías docentes de la asignatura de TFG en los grados del ámbito de la educación de las uni…
Previous fire occurrence, but not fire recurrence, modulates the effect of charcoal and ash on soil C and N dynamics in Pinus pinaster Aiton forests.
2021
Abstract Understanding the effects of fire history on soil processes is key to characterise their resistance and resilience under future fire events. Wildfires produce pyrogenic carbonaceous material (PCM) that is incorporated into the soil, playing a critical role in the global carbon (C) cycle, but its interactions with soil processes are poorly understood. We evaluated if the previous occurrence of wildfires modulates the dynamic of soil C and nitrogen (N) and microbial community by soil ester linked fatty acids, after a new simulated low-medium intensity fire. Soils with a different fire history (none, one, two or three fires) were heat-shocked and amended with charcoal and/or ash deriv…
Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study
2021
congenital bleeding disorders
Functional Bionanocomposite Fibers of Chitosan Filled with Cellulose Nanofibers Obtained by Gel Spinning
2021
Extremely high mechanical performance spun bionanocomposite fibers of chitosan (CHI), and cellulose nanofibers (CNFs) were successfully achieved by gel spinning of CHI aqueous viscous formulations filled with CNFs. The microstructural characterization of the fibers by X-ray diffraction revealed the crystallization of the CHI polymer chains into anhydrous chitosan allomorph. The spinning process combining acidic–basic–neutralization–stretching–drying steps allowed obtaining CHI/CNF composite fibers of high crystallinity, with enhanced effect at incorporating the CNFs. Chitosan crystallization seems to be promoted by the presence of cellulose nanofibers, serving as nucleation sites for the gr…
Ecosystem dynamics: exploring the interplay within fintech entrepreneurial ecosystems
2021
AbstractScholars and practitioners continue to recognize the crucial role of entrepreneurial ecosystems (EEs) in creating a conducive environment for productive entrepreneurship. Although EEs are fundamentally interaction systems of hierarchically independent yet mutually dependent actors, few studies have investigated how interactions among ecosystem actors drive the entrepreneurial process. Seeking to address this gap, this paper explores how ecosystem actor interactions influence new ventures in the financial technology (fintech) EE of Singapore. Guided by an EE framework and the use of an exploratory-abductive approach, empirical data from semi-structured interviews is collected and ana…
Social media adoption in Italian firms. Opportunities and challenges for lagging regions
2021
Social media are an important growth opportunity for firms, especially small‐sized ones operating in peripheral and lagging regions. In this paper, we investigate not only whether firms are able to take this opportunity, but also if they are able to face the challenge of adopting social media at a professional level to obtain a significant economic impact, measured in terms of exporting activities. Exploring the Italian case, our empirical study indicates that smaller firms in lagging areas are more likely to adopt social media but at the same time less likely to use them at a professional level. This reflects poor strategic targets of social media adoption and lower probabilities of enteri…
Validation of a scale of attention to diversity for university teachers
2021
espanolEs tarea de las universidades afrontar los grandes retos de la educacion superior del siglo XXI creando politicas y practicas de atencion a la diversidad como parte de su responsabilidad social. Por lo que se hace imprescindible contar con instrumentos validados para conocer las actitudes y practicas educativas en atencion a la diversidad desarrolladas por el profesorado de estas instituciones. Este articulo tiene como objetivo presentar el proceso de construccion y validacion de la Escala de Creencias, Actitudes y Practicas de Atencion a la Diversidad (CAPA-PU) para Profesorado Universitario elaborada para tal fin. Esta ha sido aplicada, siguiendo un metodo de encuesta con un diseno…
Investigating the User Experience of Virtual Reality Rehabilitation Solution for Biomechatronics Laboratory and Home Environment
2021
Virtual reality (VR) technology is a promising tool in physical rehabilitation. Research indicates that VR-supported rehabilitation is beneficial for task-specific training, multi-sensory feedback, diversified rehabilitation tasks, and patient motivation. Our first goal was to create a biomechatronics laboratory with a VR setup for increasing immersion and a motion platform to provide realistic feedback to patients. The second goal was to investigate possibilities to replicate features of the biomechatronics laboratory in a home-based training system using commercially available components. The laboratory comprises of a motion platform with 6-degrees-of-freedom (Rexroth eMotion), fitted wit…
Introducing Memory in Coarse-Grained Molecular Simulations
2021
[Image: see text] Preserving the correct dynamics at the coarse-grained (CG) level is a pressing problem in the development of systematic CG models in soft matter simulation. Starting from the seminal idea of simple time-scale mapping, there have been many efforts over the years toward establishing a meticulous connection between the CG and fine-grained (FG) dynamics based on fundamental statistical mechanics approaches. One of the most successful attempts in this context has been the development of CG models based on the Mori–Zwanzig (MZ) theory, where the resulting equation of motion has the form of a generalized Langevin equation (GLE) and closely preserves the underlying FG dynamics. In…
El tesoro de Regina Turdulorum (Casas de Reina, Badajoz)
2021
Estudio monográfico del tesoro de Regina Turdulorum. 818 antoninianos, la mayoría del tipo Divo Claudio. Todas imitaciones. The Regina Turdulorum Hoard (Casas de Reina, Badajoz) was buried with 818 imitative antoniniani of Divo Claudio type, minted in copper. The vast majority of the coins bear the reverse legend CONSECRATIO. This figure makes the Regina Turdulorum hoard one of the most important in Spain and Portugal. In numismatic terms, the most common reverse type is the funeral pyre, as opposed to the eagle. In addition to this main group, there is a second group, where there are curious imitations that follow various prototypes for the manufacture of the reverse. The study of the post…
The ‘Archaeological Map of Lilybaeum’
2021
The ‘Archaeological Map of Lilybaeum’ is the result of the long-standing scientific cooperation in Marsala between Palermo and Hamburg Universities. This paper investigates the various methods of field research used to gather the necessary data for the archaeological map of ancient Lilybaeum. There will be a particular focus on the topographic survey and photogrammetric aerial survey by Remotely Piloted Aircraft System (RPAS) conducted in the years 2017–2019. The aim of the work is to highlight the impact of the results on already existing research hypotheses and the ways in which the resulting map enhances our knowledge of the ancient city of Lilybaeum.
Fortuna artística de una célebre pintura de Francisco Ribalta
2021
El presente trabajo, al poner en valor el famoso San Bruno de Ribalta expuesto en el Museo de Bellas Artes y procedente de la Cartuja de Porta Coeli, subraya la incidencia de la imagen conceptual de esta pintura en otras obras posteriores. Entre ellas la escultura de I. Vergara de la capilla de la Universidad, la estampa debida a Vicente López para ser grabada por Vicente Capilla, así como el lienzo de San Bruno, existente en el Múseo de de la Ciudad, que presidió la capilla a él dedicada en la misma cartuja. Para la determinación de la autoría de este cuadro a favor de Vicente Castelló y Amat ha resultado clave verificar la correspondencia con el boceto perteneciente al Museo Lázaro Galdia…
Crítica social en La noche de los muertos vivientes y su remake: aportaciones al rol de la mujer en el cine de terror.
2021
Tradicionalmente se ha tenido la percepción de que la mujer en el cine de terror a ocupado un rol pasivo que le llevaba a asumir, casi siempre, el papel de víctima, subyugada en todo momento a los personajes masculinos del texto fílmico. Por este motivo el cine de terror es concebido de forma habitual como un género culturalmente dominado y consumido por hombres, producido por una industria que victimiza y castiga a la mujer una y otra vez. Partiendo de esta premisa y aprovechando la crítica de corte sociopolítico presente en La noche de los muertos vivientes (Night of the Living Dead, George A. Romero, 1968) y su remake del año 1990, nos planteamos un análisis de la crítica elaborada por R…
Determination of the LD50 with the chick embryo chorioallantoic membrane (CAM) assay as a promising alternative in nanotoxicological evaluation
2021
Toxicity tests in rodents are still considered a controversial topic concerning their ethical justifiability. The chick embryo chorioallantoic membrane (CAM) assay may offer a simple and inexpensive alternative. The CAM assay is easy to perform and has low bureaucratic hurdles. At the same time, the CAM assay allows the application of a broad variety of analytical methods in the field of nanotoxicological research. We evaluated the CAM assay as a methodology for the determination of nanotoxicity. Therefore we calculated the median lethal dose (LD50), performed in vivo microscopy and immunohistochemistry to identify organ-specific accumulation profiles, potential organ damage, and the kineti…
1FRS
2021
Discontinuation of braf/mek-directed targeted therapy after complete remission of metastatic melanoma : a retrospective multicenter adoreg study
2021
The advent of BRAF/MEK inhibitors (BRAFi/MEKi) has significantly improved progression-free (PFS) and overall survival (OS) for patients with advanced BRAF-V600-mutant melanoma. Long-term survivors have been identified particularly among patients with a complete response (CR) to BRAF/MEK-directed targeted therapy (TT). However, it remains unclear which patients who achieved a CR maintain a durable response and whether treatment cessation might be a safe option in these patients. Therefore, this study investigated the impact of treatment cessation on the clinical course of patients with a CR upon BRAF/MEK-directed-TT. We retrospectively selected patients with BRAF-V600-mutant advanced non-res…
Morir en femenino:la construcción simbólica en las exequias fúnebres de María Josefa Amalia de Sajonia
2021
Este artículo ofrece un análisis de la construcción simbólica de la reina María Josefa Amalia de Sajonia, tercera esposa de Fernando VII, a través de sus exequias fúnebres celebradas en España en 1829. A través de los textos impresos de las Relaciones, Oraciones fúnebres y textos poéticos nos adentramos en el lenguaje hiperbólico que en ellos se ofrecía de la difunta, mientras que las Descripciones de las fiestas y de los cenotafios o túmulos funerarios, así como los grabados que se conservan de estos nos plantean en qué medida el lenguaje artístico contribuyó a fabricar el concepto de la reina doméstica frente a la antigua imagen de la reina cortesana, en la crisis del Antiguo Régimen. En …
El mito aéreo en el futurismo italiano:del periodo heroico a la espiritualidad aérea (1909-1944) The aerial myth of Itanian futurism: from the heroic…
2021
La poética de lo aéreo atravesó transversalmente la historia del futurismo italiano. El undécimo punto de su manifiesto y fundación en 1909, hizo referencia al aeroplano como una máquina esencial para comprender que la vida y el arte se debían someter a un mundo en permanente transformación. Lo aéreo y sus implicaciones compusieron proclamas y manifiestos determinando la creación literaria y artística del periodo heroico. En los años treinta, cuando el futurismo planteaba su supervivencia en el complejo contexto social y político italiano, la aeropintura se convirtió en su línea oficial. Un perfil que, desde ese mismo momento, se bifurcó en dos tendencias complementarias: la dedicada a una …
La guerra de sexos en las comedias románticas de Howard Hawks:La fiera de mi niña (Brining Up Baby, 1938), Luna Nueva (His Girl Friday, 1940), La nov…
2021
Howard Hawks, plantea el enfrentamiento entre los sexos en buena parte de su filmografía. Comedias románticas, western o cine de aventuras comparten esta guerra de sexos que se inicia con una antipatia mutua entre los protagonistas que va evolucionando a medida que la pareja se ve inmersa en sus aventuras para transformarse en amistad, atracción, y finalmente amor. Cuatro de sus comedias La fiera de mi niña (Brining Up Baby, 1938), Luna Nueva (His Girl Friday, 1940), La novia era él ( I Was a Male War Bride, 1949) y Su juego favorito (Man´s Favorite Sport, 1964) plantean la guerra de sexos a través de una inversión de roles sexuales; mujer-activo /varón-pasivo que finalmente revierte a mode…
FOLFIRINEC: a randomized phase II trial of mFOLFIRINOX vs platinum-etoposide for metastatic neuroendocrine carcinoma of gastroenteropancreatic or unk…
2021
Abstract Background Poorly differentiated neuroendocrine carcinomas (NEC) are rare diseases with a poor prognosis. Platinum-etoposide (PE) has been the recommended first-line treatment for decades. FOLFIRINEC (NCT04325425) is a national multicenter randomized phase II study which aims to challenge this standard regimen. Methods The primary objective is to compare the median progression-free survival (PFS) under mFOLFIRINOX versus PE. The secondary objectives are to evaluate the objective response rates (ORR), median overall survival (OS), safety and quality of life. The associated real-time translational study will establish a molecular profile for each patient enrolled. Main inclusion crit…
Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Ree…
2021
The term "cutaneous lymphadenoma" was coined in this journal for an unusual lymphoepithelial cutaneous adnexal neoplasm, possibly with immature pilosebaceous differentiation. Some authors further proposed that cutaneous lymphadenoma was an adamantinoid trichoblastoma. However, although a hair follicle differentiation is widely accepted, the fact that this is a lymphoepithelial tumor is not appropriately explained by the trichoblastoma hypothesis. Our goal was to further clarify the phenotypic and genotypic features of cutaneous lymphadenoma in a series of 11 cases. Histologically, a lobular architecture surrounded by a dense fibrous stroma was present in all cases. The lobules were composed…
‘Human rights and democracy are not self-evident’ : Finnish student teachers’ perceptions on democracy and human rights education
2021
This article discusses democracy and human rights education (DHRE) in Finnish teacher education, drawing on existing literature, curricula and a survey of student teachers’ perceptions. Earlier studies suggested that DHRE in Finnish teacher education is unsystematic, implicit, and dependent on the teacher’s individual interests. These studies highlight a sense of national exceptionalism, where DHRE is assumed to be self-evident. In 2019, we conducted a survey of student teachers (n=300) in one university. Data content analysis reveals that student teachers now see DHRE as relevant and timely, and by no means self-evident. Student teachers believe that DHRE needs to be explicit and part of t…
El arca de las insaculaciones: Una obra mallorquina de Joan Oms
2021
El arca de las insaculaciones es un bien mueble del patrimonio español que aúna el valor histórico y el artístico. Su funcionalidad ligada a la elección de cargos de las antiguas instituciones de la isla de Mallorca o régimen de insaculación, se enriqueció gracias a su concepción escultórica, a su discurso manierista y a una tipología formal de la que no conocemos paralelos.
 Una investigación documental ha revelado el contrato de fabricación y en consecuencia, la fecha y autoría. Se trata de una obra realizada en 1669 por Joan Oms, escultor perteneciente a una conocida saga mallorquina. La información, inédita hasta ahora, confirma y amplía además la relación del arca existente con la…
Técnicas, modelos y transferencia en la ingeniería de puentes de la Cuba decimonónica. 1800-1860
2021
El fomento de las obras públicas como recurso de desarrollo económico y comercial tiene en la Cuba decimonónica uno de sus ejemplos nacionales más destacados. En este proceso, la implementación de la tecnología de la nueva era industrial introdujo en la isla nuevas referencias que tuvieron un impacto destacable en varios ámbitos constructivos. Este trabajo tiene como objetivo proyectar este análisis sobre la evolución de la ingeniería de puentes de los dos primeros tercios del siglo XIX. Mediante la documentación de varios proyectos, algunos inéditos, se identifican cuáles fueron sus modelos de referencia, sus vías de introducción y los canales de transferencia que tuvieron lugar a partir d…