0000000000134219

AUTHOR

José Alfredo Martínez

showing 16 related works from this author

Health-related quality of life in individuals with metabolic syndrome: A cross-sectional study

2020

Abstract Introduction and objectives Metabolic syndrome (MetS) is a combination of various cardiovascular risk factors with a major impact on morbidity and premature mortality. However, the impact of MetS on self-reported health-related quality of life (HRQoL) is unknown. This study evaluated the HRQoL in a Spanish adult population aged 55 years and older with MetS. Method A cross-sectional analysis was performed with baseline data from the PREDIMED-Plus multicentre randomized trial. The participants were 6430 men and women aged 55–75 years with overweight/obesity (body mass index ≥27 and ≤40 kg/m2) and MetS. The SF-36 questionnaire was used as a tool to measure HRQoL. Scores were calculate…

MaleCross-sectional study030204 cardiovascular system & hematologyOverweightAffect (psychology)Body Mass Indexlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialQuality of lifelawSurveys and QuestionnairesmedicineHumans030212 general & internal medicineAgedMetabolic Syndromebusiness.industryPublic Health Environmental and Occupational HealthMiddle Agedmedicine.diseaseObesityCross-Sectional StudiesQuality of LifeFemaleMetabolic syndromemedicine.symptomFamily PracticebusinessBody mass indexDemographyMedicina de Familia. SEMERGEN
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Food-Based Dietary Guidelines around the World: A Comparative Analysis to Update AESAN Scientific Committee Dietary Recommendations

2021

Food-Based Dietary Guidelines (FBDG) include dietary recommendations based on food groups according to the general and accepted nutrition principles and current scientific evidence. Adoption of FBDG contributes to the prevention of malnutrition in all its forms, promotes human health, and reduces environmental impact. The present review aims to perform an international comparative analysis of the FBDG adopted in different countries from three different continents (America, Asia, and Europe), with particular reference to the Spanish Food Safety and Nutrition Agency (AESAN, Agencia Española de Seguridad Alimentaria y Nutrición) Scientific Committee dietary recommendations. A total of twelve c…

food-based dietary guidelinesmedicine.medical_specialtyAsiahealth promotionGlobal HealthArticleNutrition PolicyScientific evidenceFood groupnational dietary recommendationsHuman healthEnvironmental healthmedicineHumansTX341-641Public healthNutrition and Dieteticsbusiness.industryNutrition. Foods and food supplyPublic healthpublic healthFood safetymedicine.diseaseSalut públicahealthy eatingDietEuropeAlimentacióMalnutritionGeographyHealth promotionFoodNorth AmericaFish <Actinopterygii>DietaDiet HealthybusinessFood Science
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Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study

2014

Background and aims: Epidemiologic and biological evidence supports an inverse association between polyphenol consumption and the risk of cardiovascular disease (CVD). However, no previous studies have prospectively evaluated the relationship between polyphenol intake and the incidence of CVD in such a comprehensive way. The aim was to evaluate the association between intakes of total polyphenol and polyphenol subgroups, and the risk of major cardiovascular events (myocardial infarction, stroke or death from cardiovascular causes) in the PREDIMED study. Methods and results: The present work is an observational study within the PREDIMED trial. Over an average of 4.3 years of follow-up, there…

Malemedicine.medical_specialtyInverse AssociationHydroxybenzoic acidFlavonolsEpidemiologyEndocrinology Diabetes and MetabolismMyocardial InfarctionMedicine (miscellaneous)Diet MediterraneanAntioxidantsLignanslaw.inventionCohort StudiesRandomized controlled trialRisk FactorslawInternal medicineHydroxybenzoatesmedicineHumansNutsPlant OilsOlive OilStrokeAgedNutrition and Dieteticsbusiness.industryIncidenceIncidence (epidemiology)Anti-Inflammatory Agents Non-SteroidalAge FactorsPolyphenolsfood and beveragesMiddle Agedmedicine.diseaseConfidence intervalDietStrokeClinical trialCardiovascular diseasesBiochemistrySpainFemaleObservational studyCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesNutrition, Metabolism and Cardiovascular Diseases
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La evaluación y seguimiento del estudiante de forma telemática: el proyecto Cuestionarios

2011

En la mayor parte de las ciencias, los ejercicios practicos son la mejor manera de adquirir y evaluar, tanto conocimientos cientificos como las habilidades y competencias necesarias para su aplicacion. Es un entrenamiento que, como en el mundo del deporte, resulta imprescindible y mejora el rendimiento. La resolucion de problemas exige una gran dedicacion del profesorado y, en este aspecto, la utilizacion de cuestionarios on-line puede ser de gran ayuda. Sin embargo, este tipo de cuestionarios tambien presentan una dificultad, que es el esfuerzo inicial necesario. Para reducir esta dificultad se planteo la elaboracion de una base de datos de cuestiones y un protocolo de exportacion.

tecnologías de la información y la comunicación cuestionarios telematicoscuestionarios telemáticos evaluación autoevaluación:PEDAGOGÍA [UNESCO]UNESCO::PEDAGOGÍA
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Mediterranean dietary pattern and depression: the PREDIMED randomized trial

2013

Background: A few observational studies have found an inverse association between adherence to a Mediterranean diet and the risk of depression. Randomized trials with an intervention based on this dietary pattern could provide the most definitive answer to the findings reported by observational studies. The aim of this study was to compare in a randomized trial the effects of two Mediterranean diets versus a low-fat diet on depression risk after at least 3 years of intervention. Methods: This was a multicenter, randomized, primary prevention field trial of cardiovascular disease (Prevencion con Dieta Mediterranea (PREDIMED Study)) based on community-dwelling men aged 55 to 80 years and wome…

MaleMediterranean diethumanosdepresiónType 2 diabetesDiet MediterraneanTriallaw.inventionRandomized controlled triallawRisk FactorsNutsDepressió psíquicamediana edadDepression (differential diagnoses)Aged 80 and overMedicine(all)ancianoPrimary preventionTraditional medicinedietaDepressionHàbits alimentarisIncidence (epidemiology)Hazard ratioDiabetesGeneral MedicineMiddle AgedLow-fatMental depressionCardiovascular DiseasesFemaleDietaaceites de plantasResearch Articlemedicine.medical_specialtyFood habitsenfermedades cardiovasculares:Ciencias de la Salud::Nutrición y dietética [Materias Investigacion]Mediterranean cookingInternal medicineStatistical significanceMediterranean dietCuina mediterràniaDiabetes Mellitusmedicinefactores de riesgoHumansPlant OilsOlive OilAgedbusiness.industrymedicine.diseaseDietnuecesDiabetes Mellitus Type 2SpainObservational studybusinessOlive oil
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Association of physical activity with body mass index, waist circumference and incidence of obesity in older adults

2018

Background There is limited, and inconsistent, data on the prospective association between physical activity and surrogate markers of adiposity in older adults. We aim to determine the prospective association of leisure time physical activity (LTPA) with body mass index (BMI), waist circumference (WC) and the incidence of obesity. Methods This prospective analysis included 7144 individuals with a mean age of 67 ± 6.2 years, from the PREvencion con DIeta MEDiterranea (PREDIMED) study. BMI and WC were measured and LTPA was recorded using the Minnesota Leisure Time Physical Activity Questionnaire. Exposure and outcome variables were calculated as cumulative average of repeated measurements. Re…

MaleWaistCross-sectional study030209 endocrinology & metabolismBody Mass Index03 medical and health sciencesLeisure Activities0302 clinical medicineSurveys and QuestionnairesmedicineHumansProspective Studies030212 general & internal medicineProspective cohort studyExerciseAbdominal obesityAgedbusiness.industryIncidenceIncidence (epidemiology)Public Health Environmental and Occupational HealthMiddle Agedmedicine.diseaseObesityConfidence intervalCross-Sectional StudiesObesity AbdominalFemaleWaist Circumferencemedicine.symptombusinesshuman activitiesBody mass indexDemographyEuropean Journal of Public Health
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Dietary glycemic index and glycemic load are positively associated with risk of developing metabolic syndrome in middle-aged and elderly adults

2015

© 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society. Objectives To evaluate how glycemic index (GI) and glycemic load (GL) are associated with the metabolic syndrome (MetS) and its features in middle-aged and elderly adults at high cardiovascular risk. Design Prospective, longitudinal, population-based cohort. Setting PREvenciõn con DIeta MEDiterránea study. Participants Men and women (N = 6,606) divided into three age groups (<65, 65-74, ≥75). Measurements Energy and nutrient intake was evaluated using a validated 137-item food frequency questionnaire. MetS and its features were defined in accordance with the criteria of the American Heart Association …

MaleGerontologyPREDIMEDRisk AssessmentGlycemic loadGlycemic loadGlycemic indexHumansMedicineLongitudinal StudiesProspective StudiesElderly adultsAgedHypertriglyceridemiabusiness.industryCholesterol HDLHypertriglyceridemiaCholesterol hdlmedicine.diseaseCardiovascular diseasePredimedMetabolic syndromeDiet RecordsGlycemic indexSpainObesity AbdominalHypertensionFemaleGeriatrics and GerontologyMetabolic syndromebusiness
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Psychological and metabolic risk factors in older adults with a previous history of eating disorder: A cross-sectional study from the Predimed-Plus s…

2021

Goals To explore affective and cognitive status, later in life, in individuals with and without previous history of eating disorder (ED), and also its association with higher risk for metabolic syndrome (MetS) symptomatology. Methods A cross-sectional analysis of 6756 adults, aged 55-75 years with overweight/obesity and MetS participating in the Predimed-Plus study was conducted. Participants completed self-reported questionnaires to examine lifetime history of ED, according to DSM-5 criteria, and other psychopathological and neurocognitive factors. Anthropometric and metabolic measurements were also collected. Results Of the whole sample, 24 individuals (0.35%) reported a previous history …

cardiovascular risk050103 clinical psychologyCross-sectional studyOverweightmetabolic syndromeBody Mass IndexFeeding and Eating Disorders03 medical and health sciences0302 clinical medicinedepressive symptomsRisk FactorsmedicineHumans0501 psychology and cognitive sciencesObesityAgedMetabolic Syndromebusiness.industry05 social sciencesMiddle AgedAnthropometrymedicine.disease030227 psychiatryPsychiatry and Mental healthClinical PsychologyEating disordersCross-Sectional Studieseating disorderFemaleneuropsychological profileMetabolic syndromemedicine.symptombusinessNeurocognitiveBody mass indexClinical psychologyPsychopathology
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High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma

2021

This research was funded by CICYT [AGL2016-75329-R] and CIBEROBN from the Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia, Innovación y Universidades, (AEI/FEDER, UE), Generalitat de Catalunya (GC) [2017SGR196]. The PREDIMED-Plus trial was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated Fondo de Investigaciones Sanitarias projects lead by J.S.-S. and J.V., including the following projects: PI13…

0301 basic medicineMediterranean dietFruit (Feed)PhysiologyClinical BiochemistryCarotenoidesLiquid chromatography030209 endocrinology & metabolismmatrix effect absorptionBiochemistryArticle03 medical and health sciences0302 clinical medicineMediterranean cookingFat intakeplasma carotenoidsMediterranean dietCuina mediterràniapolycyclic compoundsliquid chromatographyFood scienceCuina (Hortalisses)Molecular BiologyCarotenoidmass spectrometry2. Zero hungerchemistry.chemical_classificationConsumption (economics)030109 nutrition & dieteticsbioactive compoundsMass spectrometryorganic chemicalslcsh:RM1-950food and beveragesPREDIMED-Plus studyCell Biologydietary fatsphytochemicalsCarotenoidsbiological factorsCooking (Vegetables)3. Good healthlcsh:Therapeutics. PharmacologychemistryFruita (Aliment)Human plasmasense organsMatrix effect absorptionAntioxidants
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Associations between dietary polyphenols and type 2 diabetes in a cross-sectional analysis of the PREDIMED-Plus Trial: role of body mass index and sex

2019

Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a population with metabolic syndrome and how these associations depend on BMI and sex. This baseline cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes were calculated from food fr…

0301 basic medicinePhysiologyCross-sectional studyClinical BiochemistryHydroxycinnamic acidsType 2 diabetesOverweightBiochemistry0302 clinical medicinepreventionFlavonoidesmetabolitesrisk2. Zero hungereducation.field_of_studyDiabetisDiabetes1. No poverty3. Good healthObesitatDietamedicine.symptommanagementHydroxybenzoic acidHydroxybenzoic acidsPhenolic acidsPopulationmen030209 endocrinology & metabolismArticleLignansCatechins2 cohorts03 medical and health sciencesEnvironmental healthcatechins diet flavonoids hydroxybenzoic acids hydroxycinnamic acids lignans obesity phenolic acids proanthocyanidinsmedicineProanthocyanidinsObesityeducationMolecular BiologyFlavonoids030109 nutrition & dieteticsbusiness.industrylcsh:RM1-950biomarkersnutritional and metabolic diseasesCell Biologymedicine.diseaseObesityDietlcsh:Therapeutics. PharmacologyMetabolic syndromebusinessBody mass index
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Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial

2021

I.D.-L. is supported by the [FI_B 00256] from the FI-AGAUR Research Fellowship Program, Generalitat de Catalunya and M.M.-M is supported by the FPU17/00513 grant. a.-H. is supported by the [CD17/00122] grant and S.K.N. is supported by a Canadian Institutes of Health Research (CIHR) Fellowship. We also thank all the volunteers for their participation in and the personnel for their contribution to the PREDIMED-Plus trial. This research was funded by CiCYT [AGL2016-75329-R] and CIBEROBN from the Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia, Innovacion y Universidades, (AEI/FEDER, UE), Generalitat de Catalunya (GC) [2017SGR196]. The PREDIMED-Plus trial was supported by t…

MaleSíndrome metabòlica030309 nutrition & dieteticsgovernment.political_districtdigestionDiet Mediterranean0302 clinical medicineVegetablesDietary fatDietary fatsriskMetabolic Syndrome2. Zero hunger0303 health sciencesBalearic islandsEuropean researchFatty AcidsMiddle AgedMetabolic syndromeOils and fats EdibleCardiovascular diseasesFemalegenetic-variationmediterranean populationfiberBiotechnology030209 endocrinology & metabolismlipids03 medical and health sciencesPolitical scienceOlis i greixos comestiblesMediterranean dietCuina mediterràniaCooking MediterraneanHumansMUFAAgeddietary-fatdiseaseMalalties cardiovascularsPREDIMED-Plusdietary fatsmortalityPredimedCross-Sectional StudiesFruitgovernmentEdible oils and fatsEnergy IntakeabsorptionHumanitiesPUFAdietary fats Mediterranean dietFood ScienceOlive oil
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Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-…

2020

Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphenol intake and the components of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED (PREvenci&oacute

Maleevaluación del desenlace del pacienteSíndrome metabòlicaMediterranean diet030309 nutrition & dieteticshumanosstilbenesDiet MediterraneanBody Mass Indexchemistry.chemical_compound0302 clinical medicinePublic Health SurveillanceFood scienceCompostos bioactiusmediana edad2. Zero hungerMetabolic Syndromeanciano0303 health scienceseducation.field_of_studyNutrition and Dieteticsdietafood and beveragescolesterolMiddle AgedMetabolic syndromeHDL-cholesterolCholesterolPolifenolsFemaleColesterollcsh:Nutrition. Foods and food supplyPopulationDietética y nutrición030209 endocrinology & metabolismlcsh:TX341-641Dietary PolyphenolBioactive compoundsArticle03 medical and health sciencesMediterranean cookingMediterranean dietCuina mediterràniamedicineHumansvigilancia en salud públicapolifenoleseducationNutricióNutritionAgedCholesterolbusiness.industryíndice de masa corporalCholesterol HDLPolyphenolsmedicine.diseaseDietPatient Outcome AssessmentBlood pressureglignansCross-Sectional StudieschemistryPolyphenolDietary SupplementsMetabolic syndromebusinessBody mass indexBiomarkersestudios transversalesFood ScienceNutrients
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Yogurt consumption and abdominal obesity reversion in the PREDIMED study.

2016

Yogurt consumption and abdominal obesity reversion in the PREDIMED study. BACKGROUND AND AIMS: Evidence on the association yogurt consumption and obesity is not conclusive. The aim of this study was to prospectively evaluate the association between yogurt consumption, reversion of abdominal obesity status and waist circumference change in elderly. METHODS AND RESULTS: 4545 individuals at high cardiovascular risk were prospectively followed. Total, whole-fat and low-fat yogurt consumption were assessed using food frequency questionnaires. Generalized estimating equations were used to analyze the association between yogurt consumption and waist circumference change (measured at baseline and y…

0301 basic medicineMaleTime FactorsEndocrinology Diabetes and MetabolismMedicine (miscellaneous)0939-4753Logistic regressionDiet MediterraneanDieta mediterràniaRisk FactorsOdds RatioFood scienceProspective StudiesGeneralized estimating equationAbdominal obesityAged 80 and overBioquímica y tecnologíaNutrition and DieteticsAge Factorsfood and beveragesMiddle AgedCircumferenceYogurtDiet RecordsBiochemistry and technologyTreatment OutcomeCardiovascular DiseasesObesity AbdominalOlder adultsObesitatFemalemedicine.symptomWaist CircumferenceCardiology and Cardiovascular Medicinemedicine.medical_specialtyWaistIogurtBioquímica i biotecnologiaabdominal obesity03 medical and health sciencesInternal medicineWeight LossmedicineHumansAgedConsumption (economics)030109 nutrition & dieteticsbusiness.industryPREDIMED studyOdds ratiomedicine.diseaseObesityDietary FatsLogistic ModelsSpainMultivariate AnalysisLinear Modelsbusiness
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Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elde…

2021

The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research grant 2014–2019; agreement #340918; granted to M.Á.M.-G.); the official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS) which is co-funded by the European Regional Development Fund (coordinated FIS projects led by J.S-S. and J.V., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI…

Síndrome metabólicoMaleFood processingMediterranean dietNOVAObesidadÍndice de masa corporal:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineultra-processed foodMedicineTX341-641:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight [Medical Subject Headings]Body mass indexclassification systemsIncidenceIARC:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]Metabolic syndrome3. Good healthNutriciónCohortManipulación de alimentosDietaFactores de riesgo cardiometabólicoConcordanceUNC:Check Tags::Male [Medical Subject Headings]ClasificaciónClassification systemsDiet SurveysArticle03 medical and health sciencesfood processingHumans:Diseases::Cardiovascular Diseases [Medical Subject Headings]Aged030109 nutrition & dietetics:Health Care::Health Care Economics and Organizations::Organizations::International Agencies [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesity:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Blood pressure:Check Tags::Female [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Linear ModelsFast FoodsMetabolic syndromeOlder people0301 basic medicineSíndrome metabòlicaFood HandlingOverweightDiet MediterraneanPersones gransCohort Studiescardiometabolic riskEndocrinología030212 general & internal medicine:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerMetabolic SyndromeNutrition and Dietetics:Technology and Food and Beverages::Technology Industry and Agriculture::Industry::Food Industry::Food Handling [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Nutrition Surveys::Diet Surveys [Medical Subject Headings]Female:Technology and Food and Beverages::Food and Beverages::Food::Fast Foods [Medical Subject Headings]medicine.symptom:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome X [Medical Subject Headings]Dietética y nutrición:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings]Environmental healthMediterranean dietObesityAlimentos ultraprocesados:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]NutricióNutrition:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryNutrition. Foods and food supplyCardiometabolic Risk FactorsOverweightDieta mediterráneaCardiometabolic riskUltra-processed foodDietSpainIFICSobrepesoFood processingbusinessdietFood ScienceNutrients
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Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention

2016

Intervention with Mediterranean diet (MedDiet) has provided a high level of evidence in primary prevention of cardiovascular events. Besides enhancing protection from classical risk factors, an improvement has also been described in a number of non-classical ones. Benefits have been reported on biomarkers of oxidation, inflammation, cellular adhesion, adipokine production, and pro-thrombotic state. Although the benefits of the MedDiet have been attributed to its richness in antioxidants, the mechanisms by which it exercises its beneficial effects are not well known. It is thought that the integration of omics including genomics, transcriptomics, epigenomics, and metabolomics, into studies a…

0301 basic medicineMediterranean dietGene-diet interactionsAdipokineOmicsGenomicsReview030204 cardiovascular system & hematologyBiologyBioinformaticsDiet MediterraneanCardiovascularCatalysislcsh:ChemistryInorganic Chemistry03 medical and health sciences0302 clinical medicineMetabolomics:Ciencias de la Salud::Medicina preventiva [Materias Investigacion]Mediterranean dietMetabolomeAnimalsHumansPhysical and Theoretical Chemistrylcsh:QH301-705.5Molecular BiologyDieta -- Mediterrània Regió de laSpectroscopyEpigenomicsGenomecardiovascularOrganic ChemistrybiomarkersGeneral MedicineEvidence-based medicineOmicsgene-diet interactionsComputer Science ApplicationsomicsSistema cardiovascular -- Malalties -- Prevenció030104 developmental biologylcsh:Biology (General)lcsh:QD1-999Cardiovascular DiseasesMarcadors bioquímicsMetabolomeBiomarkers
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Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

2019

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts.

AdultMale0301 basic medicinemedicine.medical_specialtyMediterranean diet030209 endocrinology & metabolismContext (language use)Type 2 diabetesDiet MediterraneanCritical Care and Intensive Care MedicineDietary inflammatory indexBody Mass IndexYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineMediterranean dietHumansMedicineObesityProspective StudiesMortalityProspective cohort studyRandomized Controlled Trials as TopicInflammation030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industrySmokingHazard ratioMiddle Agedmedicine.diseaseObesityDietC-Reactive ProteinDiabetes Mellitus Type 2CohortPatient ComplianceCohort studiesFemalebusinessCRPCohort study
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