0000000001321137

AUTHOR

Jacek Jerzy Jozwiak

showing 44 related works from this author

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systema…

2020

Publisher's version (útgefin grein)

Index (economics)Servicios de SaludSUSTAINABLE DEVELOPMENT GOALS030204 cardiovascular system & hematologyuniversal health coverage; sustaibale develpment goal; global burden of disease; performance;universal health coveragesystematic analysisGlobal Burden of Disease0302 clinical medicineUniversal Health InsuranceRA042111. SustainabilityPer capitaMedical economicsDisease030212 general & internal medicine10. No inequality11 Medical and Health Scienceseffective coverage of health servicesGBD 2019 Universal Health Coverage Collaboratorseducation.field_of_studyPublic healthMedical careSjúkdómar4. Education1. No povertyHealth coveragePublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineHälsovetenskaper3142 Public health care science environmental and occupational healthHealth services3. Good healthGlobal burden of diseaseGlobal Burden of Disease; Health Expenditures; Humans; Universal Health Insurance; World Health OrganizationPurchasing power parityScale (social sciences)/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingLýðheilsauniversal health coveragCANCER SURVIVALACCESSperformanceHumanHeilsuhagfræðimedicine.medical_specialtyHealth coverage GBDGBDUniversal healthGBD 2019Population2019Health expenditures3122 CancersPopulation healthWorld Health Organization03 medical and health sciencesHealth systemsHeilbrigðisvísindiSDG 3 - Good Health and Well-beingGeneral & Internal MedicineDevelopment economicsHealth SciencesmedicineHeilbrigðisstefnasustaibale develpment goalAlþjóðaheilbrigðisstofnuninHumansQUALITYGlobal Burden of Disease StudyeducationPROGRESSDisease burdenPublic healthHealth services accessibilityCAREHeilbrigðisþjónusta//purl.org/pe-repo/ocde/ford#3.02.00 [https]Health ExpenditureFolkhälsovetenskap global hälsa socialmedicin och epidemiologi3121 General medicine internal medicine and other clinical medicineMorbilityAdministración de los Servicios de SaludMedical policyBusinessHealth ExpendituresHeilbrigðiskerfi
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P5313The association between coffee and caffeine consumption and renal function: insight from individual-level data, Mendelian randomization, and met…

2019

Abstract Background The reported relationship between coffee intake and renal function is poorly understood. Purpose By applying on two-sample Mendelian randomization (MR) and systematic review and meta-analysis we investigated the association between caffeine and coffee intake with prevalent CKD and markers of renal function. Methods For the individual data analysis we analysed the NHANES data on renal function markers and caffeine intake. MR was implemented by using summary-level data from genome-wide association studies conducted on coffee intake (N=91,462) and kidney function (N=133,413). Inverse variance weighted method (IVW), weighted median-based method, MR-Egger, MR-RAPS, MR-PRESSO …

Caffeine consumptionbusiness.industryMeta-analysisMendelian randomizationRenal functionMedicineCardiology and Cardiovascular MedicineBioinformaticsIndividual levelAssociation (psychology)businessEuropean Heart Journal
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Association of statin use and clinical outcomes in heart failure patients : a systematic review and meta-analysis

2019

Abstract Background The role of statins in patients with heart failure (HF) of different levels of left ventricular ejection fraction (LVEF) remains unclear especially in the light of the absence of prospective data from randomized controlled trials (RCTs) in non-ischemic HF, and taking into account potential statins’ prosarcopenic effects. We assessed the association of statin use with clinical outcomes in patients with HF. Methods We searched PubMed, EMBASE, Scopus, Google Scholar and Cochrane Central until August 2018 for RCTs and prospective cohorts comparing clinical outcomes with statin vs non-statin use in patients with HF at different LVEF levels. We followed the guidelines of the 2…

0301 basic medicinemedicine.medical_specialtyStatinmedicine.drug_classEndocrinology Diabetes and MetabolismClinical Biochemistry610Heart failure030204 cardiovascular system & hematologyLower risklaw.invention03 medical and health sciences0302 clinical medicineEndocrinologyRandomized controlled trialHeart failure; Hospitalization; Meta-analysis; Mortality; StatinslawInternal medicineHumansMedicineCardiac and Cardiovascular SystemsProspective StudiesMortalitylcsh:RC620-627Kardiologibusiness.industryResearchBiochemistry (medical)Hazard ratioStatinsmedicine.diseaseConfidence interval3. Good healthHospitalizationlcsh:Nutritional diseases. Deficiency diseasesMeta-analysisTreatment Outcome030104 developmental biologyMeta-analysisHeart failureHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessCohort study
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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for th…

2020

Background: Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable to interventions that protect children, prevent infection, and treat disease. Identifying subnational regions with the highest burden and mapping associated risk factors can aid in reducing preventable childhood diarrhoea. Methods: We used Bayesian model-based geostatistics and a geolocated dataset comprising 15 072 746 children younger than 5 years from 466 surveys in 94 LMICs, in combination with findings of the Global Burden of Diseases, Injuri…

Low income countriesmedicine.medical_treatment030204 cardiovascular system & hematologyGlobal HealthTHERAPYGlobal Burden of Disease0302 clinical medicinePrevalenceGlobal healthMedicineWATER030212 general & internal medicineChildren11 Medical and Health SciencesIncidenceMortality rateIncidence (epidemiology)1. No povertyGeneral Medicine3142 Public health care science environmental and occupational healthDiarrhoea3. Good healthChild PreschoolMiddle income countriesA990 Medicine and Dentistry not elsewhere classifiedTERRITORIESLife Sciences & BiomedicineInfantsDiarrheaAFRICAmedicine.medical_specialtyChildhood deathsRJsanitationDeveloping countryChildhood diarrhoeal morbidityITC-HYBRID03 medical and health sciencesMedicine General & InternalGeneral & Internal MedicineEnvironmental healthSYSTEMATIC ANALYSISLife ScienceHumansHealthcare DisparitiesOral rehydration therapyRisk factorhand washingDeveloping CountriesDisease burdenGlobal NutritionWereldvoedingScience & TechnologySEX-SPECIFIC MORTALITYbusiness.industryCHOLERAPublic healthBayes Theoremdiarrheal diseaseLocal Burden of Disease Diarrhoea CollaboratorsITC-ISI-JOURNAL-ARTICLENAHuman medicineDiarreabusiness
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study…

2022

Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories.  Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–4…

AdultMaleGlobal HealthTimeGlobal Burden of DiseaseSDG 3 - Good Health and Well-beingRisk FactorsRA0421RA0421 Public health. Hygiene. Preventive MedicineHumansAmbient air-qualityChildRespiratory Tract InfectionsAgedAged 80 and overMCCSex CharacteristicsMalnutritionPyridinolcarbamateBayes Theorem3rd-DAS3142 Public health care science environmental and occupational healthInfectious Diseases3121 General medicine internal medicine and other clinical medicineChild PreschoolFemaleParticulate MatterQuality-Adjusted Life YearsCovid-19LRI
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The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Dis…

2022

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

MedicinaRJ101Mental disordersSubstance use3121 Internal medicineEurope; Mental disorders; Mental health; Self-harm; Substance use; Young peopleCHILDRJ101 Child Health. Child health servicesSDG 3 - Good Health and Well-beingSYSTEMATIC ANALYSISInternal MedicineSelf-harmPublic Environmental & Occupational HealthRISKMCCScience & TechnologyHealth PolicyYoung people; Mental health; Mental disorders; Self-harm; Substance use; EuropeDAS3142 Public health care science environmental and occupational healthPREVALENCEEuropeMental disorderHealth Care Sciences & ServicesOncologyMental healthYoung peopleHEALTHLife Sciences & BiomedicineThe Lancet Regional Health - Europe
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P705Step by step diagnosis and management of statin intolerance: position paper from an international lipid expert panel

2019

Abstract Background Statin intolerance is a clinical syndrome whereby adverse effects associated with statin therapy (most commonly muscle symptoms) result in the discontinuation of therapy. Statin discontinuation is associated with increased risk of adverse cardiac outcomes. Many patients who initially experience adverse effects are able to tolerate statin therapy to some extent. Careful stepwise diagnosis and management of individuals who experience adverse effects is essential to enable optimal reduction of cardiovascular risk. Purpose In this Position Paper of the International Lipid Expert Panel (ILEP), we present a step by step approach to the diagnosis and practical management of sta…

medicine.medical_specialtyStatinbusiness.industrymedicine.drug_classExpert opinionMedicineANTILIPEMIC AGENTSPosition paperCardiology and Cardiovascular MedicinebusinessIntensive care medicineLipid-lowering therapyEuropean Heart Journal
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The prevalence of cardiovascular risk factors and cardiovascular disease among primary care patients in Poland: results from the LIPIDOGRAM2015 study

2020

Abstract Background Cardiovascular disease (CVD) is currently one of the leading cause of mortality in the European Union. Well-established, modifiable cardiovascular (CV) risk factors include hypertension (HTN), hypercholesterolaemia, diabetes mellitus (DM), obesity, low activity levels, poor diet and smoking. There are no current estimates on the prevalence of CV risk factors among Polish patients solely in the primary care setting. Methods A nationwide cross-sectional study, LIPIDOGRAM2015, was carried out in Poland in the 4th quarter of 2015 and 1st and 2nd quarters of 2016. 438 primary care physicians enrolled 13,724 adult patients that sought medical care for any medical reason in pri…

medicine.medical_specialtybusiness.industryCholesterolDiseaseOverweightmedicine.diseaseObesitychemistry.chemical_compoundBlood pressurechemistryDiabetes mellitusInternal medicineEpidemiologymedicinemedia_common.cataloged_instancemedicine.symptomEuropean unionCardiology and Cardiovascular Medicinebusinessmedia_commonEuropean Heart Journal
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Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17

2020

Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage o…

RJ101medicine.medical_treatmentCHILDRENZINC0302 clinical medicine030212 general & internal medicinemedia_commonGeographylcsh:Public aspects of medicine1. No povertyLow income and middle income countriesGeneral Medicine3142 Public health care science environmental and occupational health3. Good healthPeer reviewGeographyChild PreschoolA990 Medicine and Dentistry not elsewhere classifiedGeographical inequalities0605 MicrobiologyDiarrheaAFRICAInequalityDEATHSmedia_common.quotation_subject030231 tropical medicineDeveloping countryArticleRS1117 Public Health and Health Services03 medical and health sciencesMORBIDITYEnvironmental healthDIARRHEAL DISEASEmedicineHumansOral rehydration therapyHealthcare DisparitiesDeveloping CountriesModels StatisticalCHOLERAMORTALITYInfant NewbornInfantlcsh:RA1-1270Bayes TheoremMiddle incomeGLOBAL BURDENChild mortality0605 Microbiology 1117 Public Health and Health ServicesHealth Care SurveysITC-ISI-JOURNAL-ARTICLEFluid TherapyNAHuman medicineITC-GOLD
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Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study …

2020

Publisher's version (útgefin grein)

MaleLife expectancyDisability-Adjusted Life YearDiseasesDiseasecommunicable diseasesystematic analysisGlobal Burden of Disease0302 clinical medicine80 and overMedicine10. No inequalityChild11 Medical and Health SciencesinjuriesAged 80 and overeducation.field_of_studySjúkdómarDEMENTIAFALLSGeneral MedicineForvarnir3. Good healthChild PreschoolHumanGBDPopulation health03 medical and health sciencesSDG 3 - Good Health and Well-beingHumansGlobal Burden of Disease StudyeducationAgedSpatial AnalysisGlobal burdenDisabilityPreventionDISABILITYInfantSpatial AnalysiMortality rateGlobal Burden of Disease Diseases Injuries Systematic analysisPREVENTIONYears of potential life lostRisk factorsDisease studyGBD; communicable disease; injuries;ITC-ISI-JOURNAL-ARTICLELife expectancyRISK-FACTORSClinical MedicineRADemographyFötlunDánartíðniÁhættuþættir030204 cardiovascular system & hematologyRisk FactorsCause of DeathGlobal health030212 general & internal medicineMortality ratePopulation health1. No povertyDisability-Adjusted Life YearsPublic Health Global Health Social Medicine and EpidemiologyMiddle Aged3142 Public health care science environmental and occupational healthAdolescent; Adult; Age Distribution; Aged; Aged 80 and over; Cause of Death; Child; Child Preschool; Disability-Adjusted Life Years; Female; Global Burden of Disease; Humans; Infant; Infant Newborn; Male; Middle Aged; Risk Factors; Spatial Analysis; Young Adult/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingLýðheilsaFemaleCLINICAL-TRIALSAdultAdolescentPopulationGlobal healthSettore MED/01 - Statistica MedicadiseasesITC-HYBRIDYoung AdultHeilbrigðisvísindiAge DistributionGeneral & Internal MedicineMortalityPreschoolDisease burdenbusiness.industryRisk FactorKlinisk medicinInfant NewbornNewborn//purl.org/pe-repo/ocde/ford#3.02.00 [https]Folkhälsovetenskap global hälsa socialmedicin och epidemiologiÁverkarSystematic analysisNAbusiness
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Global injury morbidity and mortality from 1990 to 2017 : results from the Global Burden of Disease Study 2017

2020

Publisher's version (útgefin grein)

DánarmeinFötlunDánartíðniLífslíkurLife expectancy1106 Human Movement and Sports Sciencesburden of diseaseGlobal HealthGlobal Burden of Disease0302 clinical medicineQuality-Adjusted Life YearGlobal healthMedicineLIFE EXPECTANCY030212 general & internal medicine1506POPULATIONCause of deathOriginal ResearchRISKeducation.field_of_studyGlobal disease burdensInjuriesSjúkdómarIncidence (epidemiology)IncidencePopulation healthBurden of diseaseGlobalglobal3142 Public health care science environmental and occupational health3. Good healthDescriptive epidemiologyLýðheilsaQuality-Adjusted Life YearsPublic HealthTERRITORIESdescriptive epidemiologyHumanPopulation195 COUNTRIESPopulation healthCause of deathburden of disease; descriptive epidemiology; global; Humans; Incidence; Life Expectancy; Morbidity; Quality-Adjusted Life Years; Global Burden of Disease; Global Health; Wounds and Injuries1117 Public Health and Health Services03 medical and health sciencesAGESYSTEMATIC ANALYSISHumansMortalityeducationDisabilitySEX-SPECIFIC MORTALITYbusiness.industryFaraldsfræðiDISABILITYPublic Health Environmental and Occupational HealthQuality-adjusted life yearYears of potential life lostÁverkar1701 PsychologyLife expectancyWounds and InjuriesHuman medicineMorbiditybusiness030217 neurology & neurosurgeryDemography
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Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

2020

Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the…

MaleNutritional SciencesSpecific riskContaminación del Aire Interior030204 cardiovascular system & hematologySocioeconomic Factorsystematic analysisGlobal HealthBody Mass IndexGlobal Burden of DiseaseHealth Risk BehaviorHealth Risk BehaviorsDisease studies0302 clinical medicineRisk FactorsMETABOLIC RISKS030212 general & internal medicine11 Medical and Health SciencesFactores de Riesgo2. Zero hungereducation.field_of_studyPublic healthInjuriesPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineGBD; risck factors; attributable burden of disease;3142 Public health care science environmental and occupational health3. Good healthRelative riskEnvironmental healthHealthHypertension/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingGlobal Burden of Diseases Injuries Risk FactorsA990 Medicine and Dentistry not elsewhere classifiedFemaleLeading risk factorsGlobal Health MetricsCohort studyHumanmedicine.medical_specialtySubstance-Related DisordersPopulationUNITED-STATESRisk AssessmentDIETITC-HYBRID03 medical and health sciencesLife ExpectancyUNITED-STATES; MORTALITY; DISABILITY; POLLUTION; CLUSTERS; DIETSDG 3 - Good Health and Well-beingPOLLUTIONGeneral & Internal MedicineEnvironmental healthmedicineHumansGlobal Burden of Disease StudyRisk factoreducationGlobal burdenbusiness.industryPublic healthRisk FactorMORTALITYDISABILITYMalnutritionKlinisk medicinGlobal Burden of DiseasesEnvironmental Exposuremedicine.diseaseEnfermedades//purl.org/pe-repo/ocde/ford#3.02.00 [https]MalnutritionFolkhälsovetenskap global hälsa socialmedicin och epidemiologiYears of potential life lostSocioeconomic FactorsRisk factorsDisease studyRelative riskHyperglycemiaITC-ISI-JOURNAL-ARTICLENAClinical MedicinebusinessCLUSTERSRA
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Cardiovascular primary prevention risk factors in a nationwide survey, ABC (atrial fibrillation, high blood pressure and high cholesterol) risk facto…

2021

Abstract Background The National Health Service in England “Long Term Plan” aims to prevent 150,000 strokes and myocardial infarctions over the next 10 years. To achieve this, resources are being allocated to improve early detection of conditions strongly associated with cardiovascular disease. This includes working towards people routinely knowing their “ABC” risk factors (“A”: atrial fibrillation (AF), “B': hypertension and “C”: high cholesterol) (1). Purpose The aims of this study were to: 1) determine the proportion of participants with “A”, “B”, and “C” criteria; and 2) to identify risk factors for patients fulfilling any of these criteria. Methods LIPIDOGRAM2015 was a nationwide cross…

medicine.medical_specialtyBlood pressurebusiness.industryPrimary preventionEmergency medicinemedicineAtrial fibrillationCardiology and Cardiovascular Medicinemedicine.diseasebusinessNationwide surveyHigh cholesterolEuropean Heart Journal
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The global burden of cancer attributable to risk factors, 2010–19 : A systematic analysis for the Global Burden of Disease Study 2019

2022

Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 20…

MaleDEATHSDALY cancer risk factorsMedizinsystematic analysisGlobal HealthRisk AssessmentCancer preventionGlobal Burden of DiseaseRC0254Risk-attributable cancer deathsSDG 3 - Good Health and Well-beingRA0421Risk FactorsRA0421 Public health. Hygiene. Preventive MedicineQuality-Adjusted Life YearNeoplasmscancerHumansGlobal Burden of Disease StudyUKMedicine(all)MCCRC0254 Neoplasms. Tumors. Oncology (including Cancer)Risk FactorSmokingCOVID-193rd-DASGeneral MedicineDisability-adjusted life-yearsSOCIAL DETERMINANTSRisk assessmentsrisk factorCardiovascular and Metabolic Diseases3121 General medicine internal medicine and other clinical medicineOBESITYCancer burden/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingNeoplasmFemaleLIFE-STYLEQuality-Adjusted Life YearsHEALTHRAHumanRC
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The global distribution of lymphatic filariasis, 2000–18:a geospatial analysis

2020

Background Lymphatic filariasis is a neglected tropical disease that can cause permanent disability through disruption of the lymphatic system. This disease is caused by parasitic filarial worms that are transmitted by mosquitos. Mass drug administration (MDA) of antihelmintics is recommended by WHO to eliminate lymphatic filariasis as a public health problem. This study aims to produce the first geospatial estimates of the global prevalence of lymphatic filariasis infection over time, to quantify progress towards elimination, and to identify geographical variation in distribution of infection. Methods A global dataset of georeferenced surveyed locations was used to model annual 2000–18 lym…

medicine.medical_specialtyGeospatial analysis030231 tropical medicineElephantiasis:ELIMINATIONcomputer.software_genreArticleLocal Burden of Disease 2019 Neglected Tropical Diseases Collaborators1117 Public Health and Health Services03 medical and health sciences0302 clinical medicineRA0421Environmental healthGlobal healthmedicine030212 general & internal medicineMass drug administrationLymphatic filariasisPublic healthlcsh:Public aspects of medicineTropical diseaselcsh:RA1-1270General Medicinemedicine.disease3. Good healthQRGeographyLymphatic systemITC-ISI-JOURNAL-ARTICLEA990 Medicine and Dentistry not elsewhere classifiedITC-GOLDcomputer0605 Microbiology
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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026

2023

Background The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic; characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic; and examine expectations for future health spending and put into context the expected ne…

coordinationcommunicationoutbreak responseCOVID-19 GBDresponse planPublic Health Global Health Social Medicine and EpidemiologyGeneral Medicinecontact managementpandemic Covid 19financingepidemic alertepidemiological investigationFolkhälsovetenskap global hälsa socialmedicin och epidemiologiinternational health regulationsurveillanceGlobal burden diseasefinancing; global spending; pandemic Covid 19;global spendingpreparedne
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Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

2019

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained ra…

SurvivalRJ101Mortalidad InfantilHBUNDER-5 MORTALITYGlobal HealthPediatrics0302 clinical medicine3123 Gynaecology and paediatricsChild deathInfant MortalityEpidemiologyGlobal healthMiddle income countryNacimiento vivo030212 general & internal medicine10. No inequalityChildPOPULATIONDeveloping worldeducation.field_of_studyPublic healthMultidisciplinaryGeographyMortality ratewa_9001. No povertyRSUCCESSPediatrikA900 Others in Medicine and Dentistry3142 Public health care science environmental and occupational health3. Good healthChild MortalityDeath childrenVACCINATIONHEALTHws_100INTERVENTIONSAFRICAmedicine.medical_specialtyUnited NationsGeneral Science & Technology030231 tropical medicinePopulationDeveloping countryArticleHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]ITC-HYBRID03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterSocial JusticeRecién nacidoNeonatal deathsmedicineSYSTEMATIC ANALYSISOrganizational ObjectivesHumanseducationDeveloping Countriesbusiness.industryPublic healthInfant NewbornInfantCIVIL REGISTRATIONPaediatricsChild survivalNewbornPREVENTIONMortality rateInfant mortalitywa_320ws_200Child mortalitySocioeconomic FactorsITC-ISI-JOURNAL-ARTICLEHuman medicinePaediatrics Public health Developing worldbusinessDemography
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Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease St…

2022

Correction to Lancet Gastroenterol Hepatol 2022; 7: 627-47. Lancet Gastroenterol Hepatol. 2022 Aug;7(8):704. doi: 10.1016/S2468-1253(22)00210-2. PMID: 35809605. Background: Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal patterns of the global, regional, and national burden of colorectal cancer and its risk factors in 204 countries and territories across the past three decades. Methods: Estimates of incidenc…

AdultMED/42 - IGIENE GENERALE E APPLICATAIMPACTcolorectal cancerColorectal NeoplasmGBD 2019 Colorectal Cancer CollaboratorsHEREDITARYGlobal Burden of DiseaseCancer screeningDISPARITIESSDG 3 - Good Health and Well-beingCancer treatment strategiesRisk FactorsQuality-Adjusted Life YearCOLONGlobal studiesDALY GBD colorectal cancerrisk factorsHumansGlobal Burden of Disease StudyEarly Detection of CancerHepatologyMORTALITYGastroenterologyCancer incidence ratesMiddle AgedCancer burdenSURVIVAL/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSEXGENDERQuality-Adjusted Life YearsColorectal NeoplasmsHumanThe Lancet Gastroenterology & Hepatology
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Repositioning of the global epicentre of non-optimal cholesterol

2020

Publisher's version (útgefin grein)

MaleMyocardial Ischemia/bloodBLOOD-PRESSUREtriglicéridos0302 clinical medicineCardiovascular diseases ; Risk factorsHDL cholesterol80 and overCARDIOVASCULAR RISK-FACTORSPublic health surveillance//purl.org/pe-repo/ocde/ford#3.02.04 [https]BlóðrásarsjúkdómarSocioeconomicsmediana edadComputingMilieux_MISCELLANEOUSPOPULATIONHypercholesterolemia/bloodAged 80 and overCholesterol HDL/bloodancianoeducation.field_of_studyKólesterólriskitekijätadulto3. Good healthadulto jovenTriglycerides/bloodCardiovascular diseasesGeographyCholesterolManchester Institute for Collaborative Research on AgeingCholesterol LDL/bloodDENSITY-LIPOPROTEIN CHOLESTEROLEndokrinologi och diabetesNCD Risk Factor Collaboration (NCD-RisC)Science & Technology - Other Topics//purl.org/becyt/ford/3 [https]Westernteorema de Bayesmedicine.medical_specialtyResearchInstitutes_Networks_Beacons/MICRAHDLMedicinaHypercholesterolemiahipercolesterolemiaNursingHEART-DISEASEEndocrinology and DiabetesHigh blood cholesterol.HDL-kolesteroliArticleLDLravintoHealth risk assessment03 medical and health sciences//purl.org/becyt/ford/3.3 [https]SDG 3 - Good Health and Well-beingBlood cholesterolHumanseducationSERUM-CHOLESTEROLVLAGAgedScience & TechnologyCholesterolPublic healthOmvårdnadHuman healthVDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710Bayes TheoremATHEROSCLEROSIS SOCIETYRisk factorschemistryLipid-lowering medicationsFaculdade de Ciências SociaisEast and southeast Asiaalueelliset erotInternationalityNutrition and Disease[SDV]Life Sciences [q-bio]kolesterolihumanosMyocardial IschemiaMedizinadolescenteNon-HDL cholesterolBlood lipids030204 cardiovascular system & hematologyisquemia miocárdicachemistry.chemical_compoundCholesterol epidemiologyMEDICATION USEVoeding en ZiekteMedicine and Health SciencesAdolescent; Adult; Aged; Aged 80 and over; Bayes Theorem; Cholesterol HDL; Cholesterol LDL; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Ischemia; Stroke; Triglycerides; Young Adult; Internationality030212 general & internal medicine2. Zero hungerMultidisciplinaryMortality rateRepositioningStroke/blood1. No povertyPublic Health Global Health Social Medicine and EpidemiologycolesterolMiddle AgedVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 7103142 Public health care science environmental and occupational healthPeer reviewStrokeMultidisciplinary SciencesTrend analysis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalelipids (amino acids peptides and proteins)LIPIDSAdultAdolescentGeneral Science & TechnologyPopulationepicentre20-YEAR TRENDSYoung AdultmedicineLife Scienceddc:610accidente cerebrovascularDisease burdenTriglyceridesNutritionHigh density lipoproteinsnon-optimal cholesterolCholesterol HDLinternacionalidadCholesterol LDLTreatmentFolkhälsovetenskap global hälsa socialmedicin och epidemiologi
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EU-wide cross-sectional observational study of lipid-modifying therapy use in secondary and primary care: the DA VINCI study

2021

Abstract Aims To provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and populations and how this impacts low-density lipoprotein cholesterol (LDL-C) goal achievement. Methods and results An 18 country, cross-sectional, observational study of patients prescribed LLT for primary or secondary prevention in primary or secondary care across Europe. Between June 2017 and November 2018, data were collected at a single visit, including LLT in the preceding 12 months and most recent LDL-C. Primary outcome was the achievement of risk-based 2016 European Society of Cardiology (ESC)/European Atherosclerosis…

medicine.medical_specialtyRegistryStatinEpidemiologymedicine.drug_class030204 cardiovascular system & hematologyGuidelinesSecondary care03 medical and health sciences0302 clinical medicineEzetimibeRisk FactorsInternal medicinemedicineHumans030212 general & internal medicinePCSK9 InhibitorsDyslipidemiasSecondary preventionPrimary Health Carebusiness.industryAnticholesteremic AgentsStatinsCholesterol LDLGuidelineLipidsConfidence intervalCross-Sectional StudiesTreatment OutcomeCholesterolCardiovascular DiseasesObservational studyHydroxymethylglutaryl-CoA Reductase InhibitorsProprotein Convertase 9Cardiology and Cardiovascular MedicinebusinessBiomarkersmedicine.drugDA VINCI study
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Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

2022

Correction to Lancet Public Health 2022; 7: e657-69. Lancet Public Health. 2022 Dec;7(12):e992. doi: 10.1016/S2468-2667(22)00294-8. PMID: 36462522. Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolut…

MaleAdolescentRJ101AdolescentsGlobal Burden of DiseaseLife ExpectancyRJ101 Child Health. Child health servicesSDG 3 - Good Health and Well-beingRA0421Risk FactorsRA0421 Public health. Hygiene. Preventive MedicineHumansMortalityChildrenInterventionsMCCUnintentional injuriesPreventionPublic Health Environmental and Occupational Health3rd-DASGBD 2019 Adolescent Transport and Unintentional Injuries Collaborators3142 Public health care science environmental and occupational healthAdolescent transportPreventable causesHealthFemaleQuality-Adjusted Life YearsInvestmentMorbidityAdolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019The Lancet Public Health
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Health sector spending and spending on HIV/AIDS, tuberculosis, and malaria, and development assistance for health: progress towards Sustainable Devel…

2020

BACKGROUND: Sustainable Development Goal (SDG) 3 aims to "ensure healthy lives and promote well-being for all at all ages". While a substantial effort has been made to quantify progress towards SDG3, less research has focused on tracking spending towards this goal. We used spending estimates to measure progress in financing the priority areas of SDG3, examine the association between outcomes and financing, and identify where resource gains are most needed to achieve the SDG3 indicators for which data are available. METHODS: We estimated domestic health spending, disaggregated by source (government, out-of-pocket, and prepaid private) from 1995 to 2017 for 195 countries and territories. For …

Economic growthFinancing GovernmentPsychological interventionHIV Infectionsburden of disease030204 cardiovascular system & hematologyDISEASEALLOCATION0302 clinical medicineRA0421RA0421 Public health. Hygiene. Preventive MedicineSustainable developmentGlobal healthhealth economicsHealthcare FinancingHIV Infection030212 general & internal medicine10. No inequality11 Medical and Health SciencesDALYHealthy lives1. No povertyPublic Health Global Health Social Medicine and Epidemiology3rd-DASGeneral MedicineSustainable Development3. Good healthtuberculosisIMPOVERISHMENTTERRITORIESFinancingHumanFinancing PersonalResource (biology)Tuberculosi195 COUNTRIESDeveloping Countrie03 medical and health sciencesSDG 3 - Good Health and Well-beingAcquired immunodeficiency syndrome (AIDS)General & Internal MedicineSYSTEMATIC ANALYSISmedicineHumansBurden HIV/AIDS tubercolosis malariaHuman resourcesDeveloping CountriesSustainable developmentGovernmentAcquired Immunodeficiency SyndromeHealth economicsbusiness.industryDISABILITYCATASTROPHEGlobal Burden of Disease Health Financing Collaborator NetworkGLOBAL BURDENmedicine.diseaseMalariaSDG; health sector spending; development assistant for health.Health ExpenditureFolkhälsovetenskap global hälsa socialmedicin och epidemiologi3121 General medicine internal medicine and other clinical medicineNAHealth ExpendituresbusinessEXPENDITURE
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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

2020

Background: Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce highresolution geospatial estimates of access to drinking water and sanitation facilities. Methods: We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and…

Drinking water accessSanitationUniversal designGeographic MappingSocioeconomic FactorDISEASE0302 clinical medicineRA0421Hygiene11. SustainabilityGlobal health030212 general & internal medicineSanitationmedia_common2. Zero hungerPublic healthlcsh:Public aspects of medicine1. No povertyGeneral Medicine3142 Public health care science environmental and occupational health6. Clean waterLow-income countries3. Good healthA990 Medicine and Dentistry not elsewhere classifiedCHILD GROWTHTERRITORIESHYGIENEHuman0605 MicrobiologyDiarrheaAFRICAmedicine.medical_specialtymedia_common.quotation_subject030231 tropical medicineLocal Burden of Disease WaSH CollaboratorsDeveloping countryArticleGeographical inequalities1117 Public Health and Health Services12. Responsible consumptionDeveloping Countrie03 medical and health sciencesNUTRITIONAL INTERVENTIONSEnvironmental healthmedicineSYSTEMATIC ANALYSISHumansQUALITYSanitation/statistics & numerical dataOpen defecationImproved sanitationhand washingDeveloping CountriesModels StatisticalMiddle-income countriesDrinking WaterPublic healthlcsh:RA1-1270Bayes TheoremGLOBAL BURDENdiarrheal diseaseDIARRHEADiarrhea/epidemiologyLocal Burden of Disease WaSH CollaboratorSocioeconomic Factors0605 Microbiology 1117 Public Health and Health ServicesITC-ISI-JOURNAL-ARTICLEBusinessHuman medicineSanitation facilitiesITC-GOLD
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Association between phenotypic familial hypercholesterolaemia and telomere length in US adults: results from a multi-ethnic survey

2018

Aims: Familial hypercholesterolaemia (FH) accelerates atherosclerotic cardiovascular disease (ASCVD) and accordingly is the most potent hereditary cause of premature coronary heart disease. The association between telomere length (TL), a biological index of ageing, and FH has not been hitherto investigated. We addressed this question using data from the US National Health and Education National Surveys (NHANES, 1999-2002).Methods and results: We included individuals, who had TL measurements (with quantitative polymerase chain reaction method) and a phenotypic diagnosis of FH based on the Dutch Lipid Clinic Network (DLCN) criteria. Sample weights were applied for unequal probabilities of sel…

Malemedicine.medical_specialtyNational Health and Nutrition Examination SurveyCross-sectional studyPopulationFamilial hypercholesterolemia030204 cardiovascular system & hematologyHyperlipoproteinemia Type II03 medical and health sciences0302 clinical medicineInternal medicineMedicineHumans030212 general & internal medicineeducationNational Health and Education National Surveyseducation.field_of_studyTelomere lengthbusiness.industryMiddle AgedTelomeremedicine.diseaseNutrition SurveysObesityConfidence intervalUnited StatesCross-Sectional StudiesQuartileFemaleCardiology and Cardiovascular MedicinebusinessFamilial hypercholesterolaemiaBody mass indexEuropean Heart Journal
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Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning

2021

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitabil…

OncocercosisDecision AnalysisRC955-962Onchocerciasislaw.inventionGeographical LocationsMedical Conditions0302 clinical medicinelawArctic medicine. Tropical medicineMedicine and Health Sciences030212 general & internal medicineOnchocerca11 Medical and Health SciencesData ManagementbiologyPharmaceuticswc_695Enfermedades ParasitariasOnchocerciasi3. Good healthInfectious DiseasesGeographyTransmission (mechanics)Helminth InfectionsEngineering and TechnologyMass Drug AdministrationOnchocercaPublic aspects of medicineRA1-1270Management EngineeringCartographyHumanResearch ArticleNeglected Tropical DiseasesComputer and Information SciencesDrug Administration030231 tropical medicineDecision treewa_395Dermatologywc_765Environmentwc_885Research and Analysis MethodsSkin Diseases03 medical and health sciencesDrug TherapySDG 3 - Good Health and Well-beingDiagnostic MedicineTropical MedicineParasitic DiseasesmedicineHumansDisease EradicationSpatial analysisIvermectinData collectionReceiver operating characteristicData VisualizationDecision TreesPublic Health Environmental and Occupational Health06 Biological SciencesOnchocerciasis ; Elimination planning ; Africa ; Implementation units ; Public healthTropical Diseasesmedicine.diseasebiology.organism_classificationHealth CareROC CurvePeople and PlacesAfricaHealth StatisticsMorbidityOnchocerciasisScale (map)ForecastingPLOS Neglected Tropical Diseases
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Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study …

2022

Background: The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. Methods: For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and …

AdultMaleAlcohol DrinkingCONTROL POLICIESadult; Alcohol Drinking; Child Preschool; Female; Geography; Global Burden of Disease; Global Health; Humans; Male; Middle Aged; Quality-Adjusted Life Years; Risk FactorsNDASALL-CAUSEGUIDELINESGlobal HealthGBD 2020 Alcohol CollaboratorsGlobal Burden of DiseaseCOST-EFFECTIVENESSMedicine General & InternalDRINKINGSDG 3 - Good Health and Well-beingRA0421Risk FactorsGeneral & Internal MedicineQuality-Adjusted Life YearRA0421 Public health. Hygiene. Preventive MedicineDRINKERSHumansChildPreschool11 Medical and Health SciencesMETAANALYSISMCCScience & Technologyglobal burden of diseaseGeographyRisk FactoradultGeneral MedicineMiddle AgedCANCERalcohol drinkingACChild Preschool3121 General medicine internal medicine and other clinical medicineFemaleQuality-Adjusted Life YearsREDUCED MORTALITYLife Sciences & Biomedicinealcohol drinking; global burden of disease; adultHuman
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Changes in disease burden in Poland between 1990-2017 in comparison with other Central European countries: A systematic analysis for the Global Burde…

2020

Background Systematic collection of mortality/morbidity data over time is crucial for monitoring trends in population health, developing health policies, assessing the impact of health programs. In Poland, a comprehensive analysis describing trends in disease burden for major conditions has never been published. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides data on the burden of over 300 diseases in 195 countries since 1990. We used the GBD database to undertake an assessment of disease burden in Poland, evaluate changes in population health between 1990–2017, and compare Poland with other Central European (CE) countries. Methods The results of GBD 2017 for …

MaleSystems AnalysisPulmonology030204 cardiovascular system & hematologyGlobal HealthPathology and Laboratory MedicineGeographical locationsGlobal Burden of DiseaseSelf Harm0302 clinical medicineEndocrinologySex factorsRisk FactorsGlobal healthMedicine and Health SciencesMedicinePublic and Occupational Health030212 general & internal medicineChild2. Zero hungerAged 80 and overMultidisciplinaryOrganic CompoundsQ1. No povertyRMiddle Aged3. Good healthEuropeChemistryChild PreschoolPhysical SciencesMedicineFemaleQuality-Adjusted Life YearsResearch ArticleBurden of diseaseAdultCross-Cultural ComparisonAdolescentEndocrine DisordersChronic Obstructive Pulmonary DiseaseScienceLower Back PainMEDLINEPainPopulation health03 medical and health sciencesYoung AdultSigns and SymptomsLife ExpectancySex FactorsDiagnostic MedicineEnvironmental healthburden of disease Poland epidemiologyMental Health and PsychiatryDiabetes MellitusHumansEuropean UnionDisease burdenAgedbusiness.industryMortality PrematureOrganic ChemistryChemical CompoundsInfant NewbornInfantQuality-adjusted life yearAlcoholsMetabolic DisordersPolandPeople and placesbusinessPLoS ONE
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Mapping disparities in education across low- and middle-income countries

2020

Educational attainment is an important social determinant of maternal, newborn, and child health1–3. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting4–6. The global health agenda is increasingly focused on evidence of precision public health, which illustrates the subnational distribution of disease and illness7,8; however, an agenda focused on future equity must integrate comparable evidence on the distribution of social determinants of health9–11. Here we expand on the available precision SDG evidence by estimating the subnational distribution of educational attainment, including the proporti…

MaleATTAINMENTHealth StatusDiseaseeducation; low- and middle-income countries0302 clinical medicineWORLDgenderGlobal healthrisk factors030212 general & internal medicineAetiology10. No inequalitymedia_commonDeveloping worldPediatricMultidisciplinaryR1. No povertyMultidisciplinary SciencesGeographyScience & Technology - Other TopicsFemaleHEALTHdeveloping worldsocial and economic factorsEngineering sciences. TechnologydisparitieAFRICAmedicine.medical_specialty330InequalityGeneral Science & Technologymedia_common.quotation_subjectMODELSDeveloping countryLocal Burden of Disease Educational Attainment CollaboratorsArticleHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]Education03 medical and health sciences2.3 PsychologicalmedicineHumansSocietySocial determinants of healthDeveloping CountriesScience & TechnologyEquity (economics)MORTALITYPublic healthBayes TheoremEducational attainment3141 Health care sciencesocietyGood Health and Well BeingRisk factorsSocioeconomic FactorsDemographic economics030217 neurology & neurosurgery
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Estimating global injuries morbidity and mortality

2020

Background. While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods. In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then est…

MalePopulations/contexts1106 Human Movement and Sports SciencesGlobal injuriespopulation030204 cardiovascular system & hematologyGlobal HealthcontextscontextGlobal Burden of Disease0302 clinical medicineQuality-Adjusted Life YearGlobal health1506030212 general & internal medicineOriginal ResearchDatapopulations/contextsIncidence (epidemiology)Incidencemethodology3142 Public health care science environmental and occupational healthPeer reviewFemalePublic HealthTERRITORIESQuality-Adjusted Life Yearsdescriptive epidemiologyHumanDisabilities195 COUNTRIESstatistical issue1117 Public Health and Health Services03 medical and health sciencesAGELife ExpectancyEnvironmental healthInjury preventionSYSTEMATIC ANALYSISstatistical issuesHumansMortalityEstimationSEX-SPECIFIC MORTALITYDISABILITYPublic Health Environmental and Occupational Healthpopulations; contexts; methodology; descriptive epidemiology; statistical issues; Female; Humans; Incidence; Life Expectancy; Male; Morbidity; Quality-Adjusted Life Years; Global Burden of Disease; Global Health; Wounds and Injuriespopulations1106 Human Movement and Sports Sciences 1117 Public Health and Health Services 1701 PsychologyQuality-adjusted life yearYears of potential life lost1701 PsychologyLife expectancyEstimatesWounds and InjuriesHuman medicineMorbiditypopulations/contextInjury prevention
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Global mortality associated with 33 bacterial pathogens in 2019

2022

Background: Reducing the burden of death due to infection is an urgent global public health priority. Previous studies have estimated the number of deaths associated with drug-resistant infections and sepsis and found that infections remain a leading cause of death globally. Understanding the global burden of common bacterial pathogens (both susceptible and resistant to antimicrobials) is essential to identify the greatest threats to public health. To our knowledge, this is the first study to present global comprehensive estimates of deaths associated with 33 bacterial pathogens across 11 major infectious syndromes. Methods: We estimated deaths associated with 33 bacterial genera or species…

MaleBacteriaSyndromeBacterial InfectionsGeneral MedicineGlobal HealthGlobal Burden of DiseaseRisk FactorsSepsisHumansFemaleMortalityChildAfrica South of the SaharaLancet
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Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from th…

2020

Incluye: Correction: Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017. Inj Prev. 2020 Oct;26(Supp 1):i164. doi: 10.1136/injuryprev-2019-043296corr1. Epub 2020 Sep 28. PMID: 32989004 Background: The epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjuste…

Epidemiologyburden of disease; descriptive epidemiology; epidemiologyECONOMIC-DEVELOPMENT1106 Human Movement and Sports SciencesPoison controlburden of diseaseGlobal HealthGlobal Burden of Disease0302 clinical medicineQuality-Adjusted Life YearGlobal health030212 general & internal medicine10. No inequality1. No povertyBurden of diseaseDALYS3142 Public health care science environmental and occupational healthddc:3. Good healthDescriptive epidemiologyEpidemiological transitionREGISTRATIONDisabled PersonepidemiologyPublic Healthdescriptive epidemiologyHumanmedicine.medical_specialtyDEATHSAdolescent1117 Public Health and Health Services03 medical and health sciencesLife ExpectancyInjury preventionSYSTEMATIC ANALYSISmedicineDisability-adjusted life yearDisease burdenEstimationburden of disease descriptive epidemiology epidemiologyMORTALITYPublic healthEPIDEMIOLOGIC TRANSITIONPublic Health Environmental and Occupational Health030208 emergency & critical care medicineTRENDSEXPECTANCY HALE1701 PsychologyWounds and InjuriesHuman medicineDemography
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The burden of injury in Central, Eastern, and Western European sub-region: a systematic analysis from the Global Burden of Disease 2019 Study

2022

Abstract Background Injury remains a major concern to public health in the European region. Previous iterations of the Global Burden of Disease (GBD) study showed wide variation in injury death and disability adjusted life year (DALY) rates across Europe, indicating injury inequality gaps between sub-regions and countries. The objectives of this study were to: 1) compare GBD 2019 estimates on injury mortality and DALYs across European sub-regions and countries by cause-of-injury category and sex; 2) examine changes in injury DALY rates over a 20 year-period by cause-of-injury category, sub-region and country; and 3) assess inequalities in injury mortality and DALY rates across the countries…

Science & TechnologyInjuriesDEATHSPublic Health Environmental and Occupational HealthBurden of diseasePublic Health Global Health Social Medicine and Epidemiology3121 Internal medicineBurden of disease; Injuries; Disability adjusted life years; Mortality; Europe3142 Public health care science environmental and occupational health1117 Public Health and Health ServicesInjurieDisability adjusted life yearsEuropeFolkhälsovetenskap global hälsa socialmedicin och epidemiologiSDG 3 - Good Health and Well-beingINEQUALITIESPublic HealthHuman medicineDisability adjusted life yearMortalityLife Sciences & BiomedicinePublic Environmental & Occupational Health
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The cholesterol paradox in atrial fibrillation: results from the LIPIDOGRAM 2015 study

2020

Abstract Background High blood lipid levels are known risk factors for atherosclerotic cardiovascular events, but associations between lipid levels and atrial fibrillation (AF) are unclear. Some previous studies have suggested an inverse association between lipid levels and AF referred to as the “cholesterol paradox”. Purpose To examine the prevalence of AF by differing lipid levels in a large population-based study of almost 14,000 adults in Poland. Methods The LIPIDOGRAM 2015 study is a cross-sectional study of adults aged 18 years and older recruited in Poland in 2015/2016 by 438 family physicians. Poisson regression models with robust variance were used to estimate prevalence ratios (PR…

Cardiovascular eventmedicine.medical_specialtyCholesterolbusiness.industryCardiac arrhythmiaAtrial fibrillationLipid Measurementmedicine.diseaseDrug usagechemistry.chemical_compoundWaist–hip ratiochemistryInternal medicineCardiologymedicineLDL Cholesterol Lipoproteinslipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
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Global, regional, and national burden of stroke and its risk factors, 1990–2019 : a systematic analysis for the Global Burden of Disease Study 2019

2021

Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]…

MaleAging030204 cardiovascular system & hematologyStroke dataGUIDELINES3124 Neurology and psychiatryBody Mass IndexGlobal Burden of Disease0302 clinical medicineRA0421Risk FactorsEpidemiologyStrokesYOUNG-ADULTSPrevalence80 and overAetiology610 Medicine & healthStrokePOPULATION1103 Clinical Sciences 1109 NeurosciencesCause of deathAged 80 and overeducation.field_of_studyMortality rateIncidence (epidemiology)Incidence1. No povertyArticlesHälsovetenskaperMiddle AgedStroke typesddc:3. Good healthStrokeISCHEMIC-STROKEIncomeFemaleQuality-Adjusted Life YearsLife Sciences & BiomedicineAdultmedicine.medical_specialtyGBDPopulationClinical SciencesClinical Neurology610 Medicine & health03 medical and health sciencesClinical ResearchMIDDLE-INCOME COUNTRIESHealth SciencesmedicineHumansRisk factoreducationGBD 2019 Stroke CollaboratorsCerebral HemorrhageAgedIschemic StrokeGlobal burdenScience & TechnologyNeurology & NeurosurgeryHYPERTENSIONbusiness.industryMORTALITYPrevention3112 NeurosciencesNeurosciences1103 Clinical SciencesSERVICESSubarachnoid Hemorrhagemedicine.diseasePREVENTIONBrain DisordersGood Health and Well BeingAttributable riskHuman medicineNeurology (clinical)Neurosciences & Neurologybusiness1109 Neurosciences030217 neurology & neurosurgeryDemography2.4 Surveillance and distributionRC
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Global trends of hand and wrist trauma: A systematic analysis of fracture and digit amputation using the Global Burden of Disease 2017 Study

2020

BackgroundAs global rates of mortality decrease, rates of non-fatal injury have increased, particularly in low Socio-demographic Index (SDI) nations. We hypothesised this global pattern of non-fatal injury would be demonstrated in regard to bony hand and wrist trauma over the 27-year study period.MethodsThe Global Burden of Diseases, Injuries, and Risk Factors Study 2017 was used to estimate prevalence, age-standardised incidence and years lived with disability for hand trauma in 195 countries from 1990 to 2017. Individual injuries included hand and wrist fractures, thumb amputations and non-thumb digit amputations.ResultsThe global incidence of hand trauma has only modestly decreased since…

Malemedicine.medical_treatmentHandsWristburden of diseaseGlobal HealthGlobal Burden of Disease0302 clinical medicineLIFE EXPECTANCY1506030212 general & internal medicinehand injuryPOPULATIONOriginal Research030222 orthopedicseducation.field_of_studyIncidenceIncidence (epidemiology)Hand InjuriesWristsWristWrist Injuries3142 Public health care science environmental and occupational health3. Good healthPREVALENCEmedicine.anatomical_structureFemaleQuality-Adjusted Life YearsTERRITORIESdescriptive epidemiologymedicine.medical_specialtyPopulation195 COUNTRIESThumbAmputation Surgical03 medical and health sciencesAGEmedicineTraumasHumanseducationHand injurySEX-SPECIFIC MORTALITYbusiness.industryPublic Health Environmental and Occupational HealthEASTERN-EUROPEAmputationsmedicine.diseaseNumerical digitAmputationHEALTH-CAREPhysical therapyLife expectancyINJURIESbusinessFractures
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The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017 : a systematic analysis for the Global Bu…

2020

Background\ud \ud Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We report on results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 on the burden of cirrhosis and its trends since 1990, by cause, sex, and age, for 195 countries and territories.\ud \ud \ud \ud Methods\ud \ud We used data from vital registrations, vital registration samples, and verbal autopsies to estimate mortality. We modelled prevalence of total, compensated, and decompensated cirrhosis on the bas…

Liver CirrhosisMaleCirrhosisCost-Benefit AnalysisHEPATITIS-BGlobal Burden of DiseaseLiver diseaseDisability Evaluation0302 clinical medicineBurden Global Mortality CirrhosisNon-alcoholic Fatty Liver DiseaseRisk FactorsFIBROSISEurope EasternPOPULATIONAged 80 and overeducation.field_of_studySingaporeMortality rate1. No povertyGastroenterologyHepatitis CHepatitis BMiddle AgedHepatitis BHepatitis C3. Good healthPREVALENCE030220 oncology & carcinogenesisAsia Central030211 gastroenterology & hepatologyEgyptFemaleQuality-Adjusted Life YearsViral hepatitisLife Sciences & BiomedicineAdultEUROPEPopulationGBD 2017 Cirrhosis CollaboratorsArticle03 medical and health sciencesLIVER-DISEASEmedicineHumanseducationLiver Diseases AlcoholicAfrica South of the SaharaAgedScience & TechnologyHepatologyGastroenterology & Hepatologybusiness.industryMORTALITYDISABILITYDECOMPENSATIONmedicine.diseaseYears of potential life lostEarly DiagnosisSocioeconomic Factors3121 General medicine internal medicine and other clinical medicineINJURIESHuman medicinebusinessDemographyRCLancet gastroenterology & hepatology
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Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

2020

Artículo con numerosos autores, sólo se mencionan el primero, los de la UAM y grupo colectivo

MaleLocal patternsDouble burdenBörnResearch & Experimental MedicineSjúkdómseinkenniDOUBLE BURDENChildhood overweightLífefnafræðiLæknisfræði0302 clinical medicineSyndemicChild11 Medical and Health Sciencesunder 5 years of ageGeneral Medicine3. Good healthGeographyMedicine Research & ExperimentalChild PreschoolIncomeGROWTHAFRICAmedicine.medical_specialtyBiochemistry & Molecular BiologyRJMedicinaImmunologyeducationMODELSwa_395General Biochemistry Genetics and Molecular BiologyArticleG03 medical and health sciencesHumansAuthor CorrectionDeveloping CountriesPovertyBiologyLBD Double Burden of Malnutrition CollaboratorsDemographyScience & TechnologyWasting SyndromePublic healthMORTALITYInfantNæringarskorturmedicine.diseaseObesityTRENDSsigns and symptomsSocial ClassRisk factorsSameindalíffræðiITC-ISI-JOURNAL-ARTICLEUNDERNUTRITIONHuman medicineClinical Medicine030217 neurology & neurosurgeryPediatric ObesityobesityOffitaÁhættuþættirGeographic MappingOverweightRA0421Global healthrisk factors030212 general & internal medicineSigns and symptomsWastingMalnutrition Global Burden of Diseases Global Nutrition low- and middle-income countries2. Zero hungerPublic health1. No povertyPublic Health Global Health Social Medicine and EpidemiologyA900 Others in Medicine and DentistryChildhood wastingPREVALENCEChemistryMappingFemaleLýðheilsamedicine.symptomLife Sciences & BiomedicineGROWTH FAILURENutritional StatusmalnutritionITC-HYBRIDws_115childrenEnvironmental healthmedicineErfðafræðiObesitywd_200MalnutritionInfant NewbornKlinisk medicinCell BiologyOverweightMalnutritionFolkhälsovetenskap global hälsa socialmedicin och epidemiologi3121 General medicine internal medicine and other clinical medicineNA
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Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases S…

2022

Background: Disability and mortality burden of non-communicable diseases (NCDs) have risen worldwide; however, the NCD burden among adolescents remains poorly described in the EU. Methods: Estimates were retrieved from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Causes of NCDs were analysed at three different levels of the GBD 2019 hierarchy, for which mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) were extracted. Estimates, with the 95% uncertainty intervals (UI), were retrieved for EU Member States from 1990 to 2019, three age subgroups (10–14 years, 15–19 years, and 20–…

Malemortality burdenAdolescentRJRJ101CareGlobal Burden of DiseaseLife ExpectancyRJ101 Child Health. Child health servicesSDG 3 - Good Health and Well-beingRA04213123 Gynaecology and paediatricsRisk FactorsRA0421 Public health. Hygiene. Preventive MedicineDevelopmental and Educational PsychologyHumansDisabled PersonsNoncommunicable DiseasesFutureDeterminantsMCCDisabilityPublic Health Global Health Social Medicine and EpidemiologyBurden of non-communicable diseases among adolescents aged 10–24 years in the EU 1990–2019: a systematic analysis of the Global Burden of Diseases Study 20193rd-DASDisability; mortality burdenFolkhälsovetenskap global hälsa socialmedicin och epidemiologin/aHealthPediatrics Perinatology and Child HealthFemaleRA
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Additional file 3 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

2023

Additional file 3: Supplemental figures.Figure S1. Prevalence of male circumcision. Figure S2. Prevalence of signs and symptoms of sexually transmitted infections. Figure S3. Prevalence of marriage or living as married. Figure S4. Prevalence of partner living elsewhere among females. Figure S5. Prevalence of condom use during most recent sexual encounter. Figure S6. Prevalence of sexual activity among young females. Figure S7. Prevalence of multiple partners among males in the past year. Figure S8. Prevalence of multiple partners among females in the past year. Figure S9. HIV prevalence predictions from the boosted regression tree model. Figure S10. HIV prevalence predictions from the gener…

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Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the G…

2022

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution.Methods: We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regress…

Contaminación del AireHealth (social science)Type II DiabetesType 2 diabetes deathsair pollutionand YLLs attributable to all PM2·5 air pollutionMedicine (miscellaneous)and change from 1990 to 2019DALYsburden of diseaseGlobal Burden of DiseaseCarga Global de EnfermedadesMELLITUSINFLAMMATIONand household PM2·5 pollution from solid fuels in seven GBD super-regions and globally in 2019Diabetes MellitusHumansBiologyASSOCIATIONSRISKINSULIN-RESISTANCEGBD 2019 Diabetes and Air Pollution CollaboratorsHealth PolicyMaterial ParticuladoPublic Health Environmental and Occupational HealthBayes TheoremLONG-TERM EXPOSUREHumanosYLDsChemistryDiabetes Mellitus Type 23121 General medicine internal medicine and other clinical medicineAños de Vida Ajustados por Calidad de Vidaambient PM2·5 pollutionParticulate MatterQuality-Adjusted Life YearsHuman medicineFINE PARTICULATE MATTERRAType II Diabetes; air pollution; burden of disease;The Lancet Planetary Health
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Global burden of chronic respiratory diseases and risk factors, 1990-2019: an update from the Global Burden of Disease Study 2019

2023

Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019.Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated mortality, years lived with disability, years of life lost, disability-adjusted life years (DALYs), prevalence, and incidence of CRDs, i.e. chronic obstructive pulmonary disease (COPD)…

Pulmonary emphysemaLung disease;MorbidityEpidemiologyChronic obstructive pulmonary diseaseInterstitial lung diseaseGeneral MedicinePneumoconiosiAsthmaSDG 3 - Good Health and Well-beingMortality; PneumoconiosisLung diseasePneumoconiosisMorbidityMortality
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Additional file 1 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

2023

Additional file 1: Supplemental information.1. Compliance with the Guidlines for Accurate and Transparent Health Estimates Reporting (GATHER). 2. HIV data sources and data processing. 3. Covariate and auxiliary data. 4. Statistical model. 5. References.

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Additional file 2 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

2023

Additional file 2: Supplemental tables.Table S1. HIV seroprevalence survey data. Table S2. ANC sentinel surveillance data. Table S3. HIV and covariates surveys excluded from this analysis. Table S4. Sources for pre-existing covariates. Table S5. HIV covariate survey data. Table S6. Fitted model parameters.

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Additional file 4 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

2023

Additional file 4: Supplemental results.1. README. 2. Prevalence range across districts. 3. Prevalence range between sexes. 4. Prevalence range between ages. 5. Age-specific district ranges.

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