La fatigue mentale : marqueurs électrophysiologiques et stratégies de compensation

2021

Mental fatigue is a common phenomenon in modern society, causing an alteration in both cognitive and physical performances. It can lead to an increased risk of accidents, a drop in productivity, and certain disorders such as depression. The objective of this thesis work was to study this phenomenon of mental fatigue by investigating more specifically its electrophysiological markers, and to find compensatory strategies to limit and/or avoid its deleterious effects.The first study identified brain activity modulations during a prolonged modified Stroop task. An increase in theta and alpha waves, as well as a decrease in N100 and P300 amplitude reflecting a decrease in attention were observed…

Previous experience, experimentation and export survival : Evidence from firm-product-destination level data

2021

This paper explores the role of a firm's product and/or market export experience and experimentation for survival of new product-destination export spells, using firm-level Spanish customs data over the period 1997-2015. Previous research has documented a positive impact of experience on export survival. This paper contributes to the extant literature by unravelling the distinct effect on export survival of ongoing accumulated experience (i.e., from the start of a product-destination export spell), previous product and/or destination-market experience and experimentation (repetition of product-destination relationships). We find that 60% of new product-country export spells end during their…

Sentinel-3/FLEX Biophysical Product Confidence Using Sentinel-2 Land-Cover Spatial Distributions

2021

The estimation of biophysical variables from remote sensing data raises important challenges in terms of the acquisition technology and its limitations. In this way, some vegetation parameters, such as chlorophyll fluorescence, require sensors with a high spectral resolution that constrains the spatial resolution while significantly increasing the subpixel land-cover heterogeneity. Precisely, this spatial variability often makes that rather different canopy structures are aggregated together, which eventually generates important deviations in the corresponding parameter quantification. In the context of the Copernicus program (and other related Earth Explorer missions), this article propose…

Eight Simple Guidelines for Improved Understanding of Transformations and Nonlinear Effects

2021

Jyväskylästä kirjoitettiin: Käyn läpi Extra-Vipusessa ristiriitaisiksi luokitettuja yhteisjulkaisuja. Julkaisu " Eight Simple Guidelines for Improved Understanding of Transformations and Nonlinear Effects" on meillä laitettu A2 ja teillä A1. Meillä varmaan päädytty tuohon A2:een kun tiivistelmässä sanotaan "Building on a systematic review of six leading management journals..". Mutta mitä mieltä olette, kumpi olisi parempi? Transforming variables before analysis or applying a transformation as a part of a generalized linear model are common practices in organizational research. Several methodological articles addressing the topic, either directly or indirectly, have been published in the rec…

Observation of a Near-Threshold Structure in the K+ Recoil-Mass Spectra in e+e−→K+(Ds−D*0+Ds*−D0)

2021

We report a study of the processes of e^{+}e^{-}→K^{+}D_{s}^{-}D^{*0} and K^{+}D_{s}^{*-}D^{0} based on e^{+}e^{-} annihilation samples collected with the BESIII detector operating at BEPCII at five center-of-mass energies ranging from 4.628 to 4.698 GeV with a total integrated luminosity of 3.7  fb^{-1}. An excess of events over the known contributions of the conventional charmed mesons is observed near the D_{s}^{-}D^{*0} and D_{s}^{*-}D^{0} mass thresholds in the K^{+} recoil-mass spectrum for events collected at sqrt[s]=4.681  GeV. The structure matches a mass-dependent-width Breit-Wigner line shape, whose pole mass and width are determined as (3982.5_{-2.6}^{+1.8}±2.1)  MeV/c^{2} and (…

We are Still Learning from Death: After CPR, Balloon Expanding Valve (Intuity Aortic Valve) Revealed to be in Position

2021

Patients with high predicated risk undergo TAVI as an alternative treatment to surgical valve replacement...

Long-term evolution of hepatocellular adenomas at MRI follow-up

2021

Background Hepatocellular adenomas (HCAs) are rare benign liver tumors. Guidelines recommend continued surveillance of patients diagnosed with HCAs, but these guidelines are mainly based on small studies or expert opinion. Purpose To analyze the long-term evolution of HCAs, including solitary and multiple lesions, and to identify predictive features of progression with MRI. Materials and Methods In a retrospective study, patients diagnosed with pathologically proven solitary or multiple HCAs between January 2004 and December 2015 were included; β-catenin-mutated HCAs and HCAs with foci of malignancy were considered to be at risk for progression. MRI examinations were analyzed, and tumor evo…

Sekcija "Arheologu un etnogrāfu pētījumi Latvijā 2018. – 2020. gadā" : Tēžu krājums

2021

Krājumā apkopotas 2021. gada 11. martā Latvijas Universitātes 79. starptautiskās zinātniskās konferences ietvaros Latvijas Universitātes Latvijas vēstures institūta organizētās sekcijas “Arheologu un etnogrāfu pētījumi Latvijā 2018. – 2020. gadā” nolasīto referātu tēzes. Tēzēs atspoguļojas LU Latvijas vēstures institūta, LU Vēstures un filozofijas fakultātes un Latvijas Nacionālā vēstures muzeja arheologu ieguldījums arheoloģiskā mantojuma un senvēstures aktuālu jautājumu izpētē. Tēzēs ietvertās atziņas balstītas padziļinātos, starpdisciplināros pētījumos, tās atspoguļo jaunu tēmu un arheoloģiskā materiāla interpretāciju meklējumus, kā arī arheoloģisko pieminekļu apzināšanas un izrakumu met…

Secondary Osseous Integration of Cementless Unicompartmental Knee Arthroplasty After Internal Fixation of a Felix Type IIIB Fracture

2021

Case A 76-year-old man presented with periprosthetic tibial plateau fracture (TPF), with a completely loosened tibial component 3 weeks after cementless unicompartmental knee arthroplasty (UKA). Internal fixation by buttress plating was performed, and the tibial component was retained and left in situ primarily as a spacer. Revision was planned after fracture consolidation, but at 3 months, the patient was able to walk without support, without pain, and with full range of motion. At 1 year, he is free of complaints. The initial loosened tibial component reintegrated. Conclusion Internal fixation combined with preserving the loosened tibial component may be a treatment option for TPF involvi…

Peri-implantitis-like medication-related osteonecrosis of the jaw: Clinical considerations and histological evaluation with confocal laser scanning m…

2021

Objective: In the recent years, an increasing number of peri-implant medication-related osteonecrosis of the jaw (PI-MRONJ) have been reported in literature, both in oncologic and osteoporotic patients. The aim of this study is to describe 19 cases of patients previously diagnosed as affected by peri-implantitis, who were treated for PI-MRONJ, with consideration on clinical and histopathological features. Materials and Methods: Patients included were affected by postmenopausal osteoporosis and were administered with different antiresorptive drugs. Due to the presence of clinical and radiological signs of peri-implantitis not healed after non-surgical periodontal treatment, they were referre…

Implementación y uso clínico de la radioterapia adaptativa. Informe del grupo de trabajo de radioterapia adaptativa de la Sociedad Española de Física…

2021

La radioterapia adaptativa (Adaptive Radiation Therapy, ART) se puede definir como la modificación del plan de tratamiento administrado a un paciente durante el curso de la radioterapia para tener en cuenta los cambios en la anatomía.
 La aplicación de ART supone un cambio en el proceso radioterápico que implica el uso de numerosos recursos adicionales, no estando implementada de forma general. Así, aun tratándose de una idea introducida hace más de 20 años, todavía a fecha de hoy son objeto de estudio muchos de los aspectos que definen la ART: la decisión de proceder a la nueva planificación del tratamiento, el momento óptimo para adaptar el plan, el umbral dosimétrico o anatómico que…

Utopies organicistes et régulations corporatistes dans les dissertations doctorales portugaises du second XIXe siècle. Les rêveries krausistes des mi…

2021

Convinced by the importance of social regulation, Portuguese legal Krausism developed a harmonic or social liberalism capable of protecting workers by proposing an association of industrial classes. These projects remained doctrinal, set out in university theses. This utopia with corporatist contours was carried by three Krausists from the Faculty of Law of Coimbra: Adrião Forjaz and his two disciples, the future ministers Mártens Ferrão and Costa Lobo.

The Role of Synthetic A Priori Propositions in the Development of Kant’s Account of Practical Autonomy: A Critique of Watkins’ Reading of Kant’s Prol…

2021

AbstractI draw attention to a 12-page Vorarbeit to Kant’s Prolegomena from the so-called Scheffner-Nachlaß and argue that the parallel Kant draws there between the possibility of theoretical and practical synthetic a priori propositions provides important insight into the development of his account of practical autonomy in the Groundwork. Based on a brief sketch of the role synthetic a priori propositions play in the development of Kant’s critical philosophy, I conclude that for Kant the objective validity of any science depends on the objective validity of a number of synthetic a priori propositions.

Frontal Electroencephalogram Alpha Asymmetry during Mental Stress Related to Workplace Noise

2021

This study aims to investigate the effects of workplace noise on neural activity and alpha asymmetries of the prefrontal cortex (PFC) during mental stress conditions. Workplace noise exposure is a pervasive environmental pollutant and is negatively linked to cognitive effects and selective attention. Generally, the stress theory is assumed to underlie the impact of noise on health. Evidence for the impacts of workplace noise on mental stress is lacking. Fifteen healthy volunteer subjects performed the Montreal imaging stress task in quiet and noisy workplaces while their brain activity was recorded using electroencephalography. The salivary alpha-amylase (sAA) was measured before and immedi…

Regio- and Stereoselective Chloro Sulfoximidations of Terminal Aryl Alkynes Enabled by Copper Catalysis and Visible Light

2021

Advanced synthesis & catalysis 2552-2556 (2021). doi:10.1002/adsc.202100162

Las Preferencias Musicales de los Estudiantes: hacia un reconocimiento de sus Identidades Culturales

2021

Diversas tradiciones de educación musical crítica sostienen la necesidad de reconocer las identidades de los estudiantes mediante la incorporación curricular de sus preferencias musicales, las cuales pertenecen principalmente a la música popular urbana. Sin embargo, esta todavía no es utilizada de manera generalizada en los diferentes sistemas educativos y es comúnmente rechazada por los docentes, quienes la consideran estéticamente inferior. No obstante, un conocimiento en profundidad de la construcción e implicaciones psicosociales de dichas preferencias podría contribuir a aumentar su inclusión en el ámbito educativo. En este sentido, este artículo realiza una revisión bibliográfica de 1…

A CURIOSITY FORM THE WESLEY CLAIR MITCHELL PAPERS: FAY ON MARSHALL AND SOME CONTROVERSIAL MATTER

2021

This brief note reproduces some archival material which shed new light on Marshall.

Pool choice in a vertical landscape: tadpole rearing site flexibility in phytotelm-breeding frogs

2021

AbstractMany species of Neotropical frogs have evolved to deposit their tadpoles in small water bodies inside plant structures called phytotelmata. These pools are small enough to exclude large predators but have limited nutrients and high desiccation risk. Here, we explore phytotelm use by three common Neotropical species: Osteocephalus oophagus, an arboreal frog that periodically feeds eggs to its tadpoles; Dendrobates tinctorius, a tadpole-transporting poison frog with cannibalistic tadpoles; and Allobates femoralis, a terrestrial tadpole-transporting poison frog with omnivorous tadpoles. We found that D. tinctorius occupies pools across the chemical and vertical gradient, whereas A. fem…

Hard to catch: Experimental evidence supports evasive mimicry

2021

Most research on aposematism has focused on chemically defended prey, but the signalling difficulty of capture remains poorly explored. Similar to classical Batesian and Müllerian mimicry related to distastefulness, such ‘evasive aposematism' may also lead to convergence in warning colours, known as evasive mimicry. A prime candidate group for evasive mimicry areAdelphabutterflies, which are agile insects and show remarkable colour pattern convergence. We tested the ability of naive blue tits to learn to avoid and generalizeAdelphawing patterns associated with the difficulty of capture and compared their response to that of birds that learned to associate the same wing patterns with distast…

Die deutsche Version der Level of Personality Functioning Scale-Brief Form 2.0 (LPFS-BF): Faktorenstruktur, konvergente Validität und Normwerte in de…

2021

ZusammenfassungDas alternative DSM-5-Modell der Persönlichkeitsstörungen definiert als Kernmerkmal aller Persönlichkeitsstörungen das Funktionsniveau der Persönlichkeit, das wiederum über Probleme mit dem Selbst (Selbstpathologie) und Probleme im zwischenmenschlichen Bereich (interpersonale Pathologie) operationalisiert wird. Als kurzes Selbstbeurteilungsverfahren zur Diagnostik des Funktionsniveaus der Persönlichkeit ist die 12 Items umfassende Level of Personality Functioning Scale-Brief Form 2.0 (LPFS-BF) von einer niederländischen Arbeitsgruppe entwickelt worden. In dieser Studie wurde die deutsche Version der LPFS-BF erstmals an einer großen und repräsentativen Allgemeinbevölkerungssti…

Triggers of Exacerbation in Chronic Urticaria and Recurrent Angioedema—Prevalence and Relevance

2021

Patients with urticaria and angioedema often have triggers that cause an outbreak or a swelling episode or worsen their chronic condition. Exploring these factors with each patient may result in better understanding and control of their disease. Patients should be advised to avoid known triggers, if feasible, or prepare to prevent or control an exacerbation with appropriate pretreatment if avoidance is not possible. In this review, we describe and discuss a variety of factors for which there is evidence that they cause or exacerbate chronic spontaneous urticaria and angioedema. These potentially exacerbating factors include drugs, food additives, and naturally occurring pseudoallergens, men…

Can the Excluded Criticize? On the (Im)possibilities of Formulating and Understanding Critique

2021

If critique does not want to be more than just a ‘passion of the head’ it has to engage in dialogue with the worst-off in society. However, there are several mechanisms that hinder the excluded fro...

Detection and Discrimination of Inter-Turn Short Circuit and Demagnetization Faults in PMSMs Based on Structural Analysis

2021

This paper presents a fault diagnosis method based on structural analysis of permanent magnet synchronous motors (PMSMs), focusing on detecting and discriminating two of the most common faults in PMSMs, namely demagnetization and inter-turn short circuit faults. The structural analysis technique uses the dynamic mathematical model of the PMSM in matrix form to evaluate the system’s structural model. After obtaining the analytical redundancy using the over-determined part of the system, it is divided into redundant testable sub-models. Four structured residuals are designed to detect and isolate the investigated faults, which are applied to the system in different time intervals. Finally, th…

Human Reaction Times: Linking Individual and Collective Behaviour Through Physics Modeling

2021

An individual’s reaction time data to visual stimuli have usually been represented in Experimental Psychology by means of an ex-Gaussian function. In most previous works, researchers have mainly aimed at finding a meaning for the parameters of the ex-Gaussian function which are known to correlate with cognitive disorders. Based on the recent evidence of correlations between the reaction time series to visual stimuli produced by different individuals within a group, we go beyond and propose a Physics-inspired model to represent the reaction time data of a coetaneous group of individuals. In doing so, a Maxwell–Boltzmann-like distribution appeared, the same distribution as for the velocities …

AgroTechnoPôle. Plateforme au service du développement de nouvelles solutions technologiques pour la transition agroécologique. Webinaire Axema. 10 m…

2021

National audience

Obtaining the multiple Debever null directions

2021

The explicit expression of the multiple Debever null directions of an algebraically special spacetime are obtained in terms of the electric and magnetic parts of the Weyl tensor. An algorithm for the determination of the Petrov-Bel type and the algorithm to obtain the multiple Debever null directions are implemented on the xAct Mathematica suite of packages. The corresponding notebooks with examples are provided and explained.

Ionic Liquids-Cobalt (II) Thermochromic Complexes: How the Structure Tunability Affects "Self-contained" Systems

2021

With the aim of obtaining thermochromic systems with potential applications in solar energy storage, we evaluated the behavior of some sugar-based ionic liquids (ILs)–Co(NTf₂)₂ complexes, in IL solution, as a function of temperature. Different structural changes on the cation, the nature of the anion, and the nature of the IL used as the solvent were considered. The analysis of the above factors was carried out through a combined approach of different techniques, that is, variable temperature UV–vis and NMR spectroscopies, conductivity, and thermal gravimetric analysis. The thermochromic systems were analyzed both as solutions and as thin films, and the data collected highlight the defining…

Desymmetrisierung von prochiralen Cyclobutanonen via Stickstoffinsertion: Ein einfacher Zugang zu chiralen γ‐Lactamen

2021

Proyectos de ciencia ciudadana. Una oportunidad para la alfabetización científica y la educación en sostenibilidad

2021

Des que va sorgir el terme  ciencia ciutadana  fins a l’actualitat, els projectes de participacio ciutadana han augmentat en quantitat i en diversitat d’arees d’actuacio. La ciencia ciutadana es descobreix aixi com un mecanisme per a implicar la societat, propiciar el seu interes en la ciencia i contribuir a la seua alfabetitzacio cientifica. A mes, cal destacar l’aportacio inherent dels projectes de ciencia ciutadana a l’assoliment dels Objectius de Desenvolupament Sostenible (ODS). En aquest article es revisen alguns exemples de projectes de ciencia ciutadana d’ambit internacional i es detallen projectes en actiu a Espanya, tant des de la perspectiva de l’ensenyament formal com des de la …

Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak

2021

8 páginas, 2 figuras, 1 tabla.

A multi-phase multi-objective dynamic genome-scale model shows different redox balancing among yeast species in fermentation

2021

ABSTRACTYeasts constitute over 1500 species with great potential for biotechnology. Still, the yeastSaccharomyces cerevisiaedominates industrial applications and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here we propose a multi-phase multi-objective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kin…

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

2021

Acute lung injury (ALI) is a critical inflammatory syndrome, characterized by increased diffuse inflammation and severe lung damage, which represents a clinical concern due to the high morbidity and mortality in critical patients. In last years, there has been a need to develop more effective treatments for ALI, and targeted drug delivery to inflamed lungs has become an attractive research field. Here, we present a nanodevice based on mesoporous silica nanoparticles loaded with dexamethasone (a glucocorticoid extensively used for ALI treatment) and capped with a peptide that targets the TNFR1 receptor expressed in pro-inflammatory macrophages (TNFR-Dex-MSNs) and avoids cargo leakage. TNFR-D…

Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders.

2021

Abstract Background Opioids have been prescribed to reduce suffering from pain and to enhance quality of life. Due to the addictive potential and the lack of other effective alternatives to treat severe acute and chronic pains, opioids remain a serious public health issue. While, opioids directly influence the drug-seeking behavior, tolerance and withdrawal processes, through neuroadaptation, the brain's endogenous opioid system also adapts in the presence of chronic pain and could contribute to the difficulty of treatment. Despite the seemingly obvious interaction between the presence of pain and opioid-abuse, little is known about the underlying mechanisms in the brain. Purpose To review …

Perspectiva feminista como ética periodística en México

2021

La investigación tiene como propósito demostrar que la prensa feminista, debe ser considerada como herramienta en la promoción y defensa de los derechos humanos. Se desarrolló desde un enfoque cualitativo, examinando las investigaciones de cuatro reconocidas periodistas mexicanas. De los principales debates que se problematizan, se desprende que la prensa debe ser un ente vigilante de los grupos de poder. Al incluirse la perspectiva feminista en el periodismo, los mensajes que se transmiten contienen una significación práctica que intrínsecamente coadyuva en el reconocimiento de la dignidad de las mujeres. Visto lo anterior, se concluye que, en orden de construir sociedades más justas, quie…

Function of AtPGAP1 in GPI anchor lipid remodeling and transport to the cell surface of GPI-anchored proteins

2021

ABSTRACTGPI-anchored proteins (GPI-APs) play an important role in a variety of plant biological processes including growth, stress response, morphogenesis, signalling and cell wall biosynthesis. The GPI-anchor contains a lipid-linked glycan backbone that is synthesized in the endoplasmic reticulum (ER) where it is subsequently transferred to the C-terminus of proteins containing a GPI signal peptide by a GPI transamidase. Once the GPI anchor is attached to the protein, the glycan and lipid moieties are remodelled. In mammals and yeast, this remodelling is required for GPI-APs to be included in Coat Protein II (COPII) coated vesicles for their ER export and subsequent transport to the cell s…

Innovation in collaborative design: an exploratory study in hackathon

2021

International audience; Collaborative design is the use of design practices which tend to favor the integration of different experts, and to support creativity and innovation. Therefore, in this study, we were particularly interested in the collaborative design tools used in the specific context of a pedagogical hackathon. During this event, 1310 engineering students mentored by professors and industrial experts worked on around 131 industrial projects. In this article, we will present our study of the tools put in place by the participants of these innovative projects according to their training. Our study is based on a collection of project data. We will show that storyboards are often us…