showing 36 of ~574560 from 574555 documents
Tri-Marium as the ‘emancipation’ of East-Central Europe: framing European counter-narratives in Poland
2021
The historical notion of Inter-Marium captured Poland’s centuriesold concept of integrating, in a form of confederation, the new states that appeared on the map between the Baltic and Black Seas after 1918. Reincarnated as the contemporary narrative of Tri-Marium, this notion is gaining new momentum and has been most visible in Poland, the largest state of the European Union’s Eastern semi-periphery. This article examines Inter-Marium as one of the most clearly articulated counter-narratives to the mainstream European integration project. Drawing on original research rooted primarily in critical discourse analysis, the article uses framing as an interpretative tool. It analyses the narrativ…
Baseline CHA 2 DS 2 ‐VASc score and prognosis in octogenarians with non‐ST segment elevation acute coronary syndrome
2021
Background CHA2DS2-VASc Score is widely used to predict thromboembolic risk in patients with Atrial Fibrillation (AF). We sought to study if this score predicts outcomes in elderly patients with Non-ST segment Elevation Acute Coronary Syndromes (NSTEACS). Methods The multicenter LONGEVO-SCA prospective registry included 532 unselected patients with NSTEACS aged ≥80 years. Data to calculate CHA2DS2-VASc Score were available in 523 patients (98.3%). They were classified according to CHA2DS2-VASc Score: group 1 (score ≤ 4), and 2 (5-9). We studied outcomes in terms of mortality or readmission at 6 months follow-up. Results A total of 266 patients (51%) had a high CHA2DS2-VASc Score (group 2). …
Active Travel and Mild Cognitive Impairment among Older Adults from Low- and Middle-Income Countries
2021
Active travel may be an easily achievable form of physical activity for older people especially in low- and middle-income countries (LMICs), but there are currently no studies on how this form of physical activity is associated with a preclinical state of dementia known as mild cognitive impairment (MCI). Therefore, we aimed to investigate the association between active travel and MCI among adults aged ≥50 years from six LMICs. Cross-sectional, community-based data from the World Health Organization’s Study on Global Ageing and Adult Health were analyzed. The definition of MCI was based on the National Institute on Ageing-Alzheimer’s Association criteria. Active travel (minutes/week) was as…
Minding the Gaps : The Role of Finnish Civil Society Organizations in the Labour Market Integration of Migrants
2021
AbstractThe growing role of civil society organizations (CSOs) in welfare service provision is sometimes portrayed as a threat to welfare state universalism in Nordic societies. In Finland, CSOs co-produce integration services alongside comprehensive official integration programmes, compensating for gaps and shortcomings in those services. We identify three “gaps”, which are (1) limited availability of services in terms of time and target group, (2) lack of direct labour market contacts and (3) limited flexibility to serve individual needs. We assess how CSOs target these gaps with their service offerings through qualitative interviews with policy implementers, CSO workers and migrants. How…
Defending the Nordic model: Understanding the moral universe of the Norwegian working class
2021
In recent years, much attention has been paid to the white working class’ concern with their declining position in the neoliberal era. The hypothesis that social and economic insecurity provoke anger and xenophobia are unable to account for the Norwegian case. The Nordic model still acts as a buffer against neoliberal capitalism, making the white Norwegian working class less vulnerable than in comparable countries. This paper will argue that the Norwegian working class has defended the Nordic model by utilising a range of moral values. I use 56 qualitative interviews to examine the morality of the white Norwegian working class. The study is theoretically and methodologically inspired by Bol…
Intérêts du phénotypage de la personnalité pour améliorer la lutte biologique : cas d’étude chez l’auxiliaire Trichogramma evanescens
2021
One promising approach to improve the use of biological control agents (BCA) consists in the exploitation of intraspecific variation on traits related to mass-rearing or field performance. Consistent inter-individual variations in behaviour (known as personality) have never been considered in biological control (BC) while they have proved to be heritable and correlated to phenotypic traits possibly related to fitness in rearing or field conditions. The aim of this PhD thesis was (i) to develop an experimental design to measure personality traits in a the egg-parasitoid Trichogramma evanescens, and (ii) to evaluate the feasibility and interest of phenotyping personality traits to set and imp…
From the barbecue to the sauna: A comparative account of the folding of media reception into the everyday life
2021
How and why do people still get print newspapers in an era dominated by mobile and social media communication? In this article, we answer this question about the permanence of traditional media in a digital media ecosystem by analyzing 488 semi-structured interviews conducted in Argentina, Finland, Israel, Japan, and the United States. We focus on three mechanisms of media reception: access, sociality, and ritualization. Our findings show that these mechanisms are decisively shaped by patterns of everyday life that are not captured by the scholarly foci on either content- or technology-influences on media use. Thus, we argue that a non-media centric approach improves descriptive fit and ad…
A Unifying Framework for Perturbative Exponential Factorizations
2021
We propose a framework where Fer and Wilcox expansions for the solution of differential equations are derived from two particular choices for the initial transformation that seeds the product expansion. In this scheme, intermediate expansions can also be envisaged. Recurrence formulas are developed. A new lower bound for the convergence of theWilcox expansion is provided, as well as some applications of the results. In particular, two examples are worked out up to a high order of approximation to illustrate the behavior of the Wilcox expansion.
Adsorption of organic compounds at the surface of Enceladus' ice grains. A grand canonical Monte Carlo simulation study
2021
International audience; In this paper, we characterise the adsorption of ethylene, propanol and hexanal molecules on crystalline ice by grand canonical Monte Carlo simulations performed at 236 K, a temperature which is typical of some Enceladus’ environments. We show that at low coverage of the ice surface, the adsorption of propanol and hexanal is driven by the interaction of these molecules with the ice phase and, as a consequence, the adsorbed molecules lie more or less parallel to the ice surface. On the other hand, upon saturation, the adsorbate–adsorbate interactions become more and more important and the molecules tend to become tilted with respect to the surface, the aliphatic chain…
Droit et passion du droit de la sécurité sociale
2021
International audience
An optimal population code for global motion estimation in local direction-selective cells
2021
AbstractNervous systems allocate computational resources to match stimulus statistics. However, the physical information that needs to be processed depends on the animal’s own behavior. For example, visual motion patterns induced by self-motion provide essential information for navigation. How behavioral constraints affect neural processing is not known. Here we show that, at the population level, local direction-selective T4/T5 neurons in Drosophila represent optic flow fields generated by self-motion, reminiscent to a population code in retinal ganglion cells in vertebrates. Whereas in vertebrates four different cell types encode different optic flow fields, the four uniformly tuned T4/T5…
Effets et implication des jeunes au sein du dispositif "Garantie jeunes"
2021
International audience
Imperfect accretion: ejecting matter in X-ray binaries
2021
X-ray binaries are binary stars composed of a compact object (a black hole, a neutron star) accreting matter from a companion star. These sources can be considered perfect astrophysical laboratories to test our knowledge of, e.g., General Relativity and Magneto-Hydrodynamics. Accretion is the key phenomenon characterizing these systems, but it is not always completely efficient. In many systems, ejections of matter are also observed, e.g. in the form of jets and winds, or also suggested, e.g. to explain the observed strong orbital expansion of a number of systems. Furthermore accretion and ejection seems to be somehow interconnected but the nature of this correlation is not completely clear…
Magnetic anisotropy in Fe/U and Ni/U bilayers
2021
Magnetometry measurements of Fe/U and Ni/U bilayer systems reveal a non-monotonic dependence of the magnetic anisotropy for U thicknesses in the range 0 nm - 8 nm, with the Fe/U bilayers showing a more prominent effect as compared to Ni/U. The stronger response for Fe/U is ascribed to the stronger 3d-5f hybridization of Fe and U. This non-monotonic behaviour is thought to arise from quantum well states in the uranium overlayers. Estimating an oscillation period from the non-monotonic data, and comparing it to Density Functional Theory calculations, we find that wavevector matches to the experimental data can be made to regions of high spectral density in (010) and (100) cuts of the electron…
Synthesis of P-Chirogenic Diphosphinotriazoles and Their Use in Asymmetric Catalysis
2021
International audience; The stereoselective synthesis of P-chirogenic diphosphinotriazoles using ephedrine methodology was described. The coordination behavior of these compounds as P,P-ligands has been demonstrated by the preparation as well as the spectroscopic and X-ray crystallographic analyses of a palladium complex. The efficiency of these new P-chirogenic diphosphines in the palladiumcatalyzed asymmetric allylic substitution reaction was also evaluated.
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2021
Patients with unilateral vocal fold cancer (T1a) have a favorable prognosis. In addition to the oncological results of CO2 transoral laser microsurgery (TOLMS), voice function is among the outcome measures. Previous early glottic cancer studies have reported voice function in patients grouped into combined T stages (Tis, T1, T2) and merged cordectomy types (lesser- vs. larger-extent cordectomies). Some authors have questioned the value of objective vocal parameters. Therefore, the purpose of this exploratory prospective study was to investigate TOLMS-associated oncological and vocal outcomes in 60 T1a patients, applying the ELS protocols for cordectomy classification and voice assessment. P…
3D in Suspension versus 2D in Adhesion: molecular profiles in stemness and mesenchymal differentiation of Spheroids from Adipose-derived Stem Cells
2021
Purpose: Adipose stem cells (ASCs) represent a reliable source of stem cells with a widely demonstrated potential in regenerative medicine and tissue engineering applications. New recent insights suggest that three-dimensional (3D) models may closely mimic the native tissue properties; spheroids from adipose derived stem cells (S-ASCs) exhibit enhanced regenerative abilities compared with those of 2D models. Stem cell therapy success is determined by “cell-quality”; for this reason, microRNA profiles, the involvement of stress signals and cellular aging need to be further investigated. Material and Methods: Adipose tissue was collected from healthy individuals, 44 females and 17 males, afte…
Toward a cognitive Discourses Semantics. Theoreticals inputs and empirical corpus-based case study in German.
2021
At the intersection between usage-based construction grammar and frame semantics, a cognitive semantic analysis is to be theorized. The present work proposes to develop for this purpose the Cognitive Discourse Analysis model. Discourse is then understood following Michel Foucault as a conceptual system based on linguistic, social and epistemic knowledge. Its linguistic operationalization is achieved through the contribution of textual linguistics and corpus following Dietrich Busse. The aim of such a methodological construction is to finely examine a corpus of recurrent texts in a cognitive perspective, and thus as close as possible to the linguistic reality, and to be able represent the en…
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2021
Abstract Insect cuticular hydrocarbons (CHCs) are highly diverse and have multiple functions, including communication and waterproofing. CHC profiles form species-specific, complex blends of up to 150 compounds. Especially in ants, even closely related species can have largely different profiles, raising the question how CHC differences are mirrored in the regulation of biosynthetic pathways. The neotropical ants Crematogaster levior and Camponotus femoratus both consist of two cryptic species each that are morphologically similar, but express strongly different CHC profiles. This is ideal to study the molecular basis of CHC differences. We thus investigated gene expression differences in f…
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2021
To foster understanding in the psychopathology of patients with anorexia nervosa (PAN) at the psychological and physiological level, standardized experimental studies on reliable biomarkers are needed, especially due to the lack of disorder-specific samples. To this end, the autonomic nervous system (ANS) response to a psychosocial stressor was investigated in n = 19 PAN (BMI: 18.7 ± 3.3 kg/m2), age, and gender-matched to n = 19 healthy controls (HC; BMI: 24.23 ± 3.0 kg/m2). For this purpose, heart rate (HR) and heart rate variability (HRV) parameters were assessed in a cross-sectional study design under two experimental conditions: (1) rest and (2) stress (Trier Social Stress Test). In add…
El doble rechazo de la reflexión en Ser y tiempo
2021
The objective of this article is to clarify the Heideggerian rejection of the idea of reflection as the method of philosophy. The need for such explanation lies on the counterintuitive nature of this philosophical thesis and on the interpretive problems that this criticism presents in Being and Time. In order to solve them, a brief historical-conceptual examination of the reflection is realized, leading to two different meanings of the concept, a psychological and a transcendental one. Thanks to this distinction, it is possible to expose systematically the double criticism presented in Being and time and, therefore, clarify the ultimate reasons underling the Heideggerian rejection of the …
Learning From Mistakes: The Role of Phages in Pandemics
2021
The misuse of antibiotics is leading to the emergence of multidrug-resistant (MDR) bacteria, and in the absence of available treatments, this has become a major global threat. In the middle of the recent severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic, which has challenged the whole world, the emergence of MDR bacteria is increasing due to prophylactic administration of antibiotics to intensive care unit patients to prevent secondary bacterial infections. This is just an example underscoring the need to seek alternative treatments against MDR bacteria. To this end, phage therapy has been proposed as a promising tool. However, further research in the field is mandatory to assure…
«Nadie comprende lo que “yo” pienso aquí»
2021
espanolLas reflexiones que Heidegger plantea sobre la ipseidad y el ser si-mismo (Selbstheit; Selbstsein) en Ser y tiempo, y que estan recibiendo un nuevo impulso hermeneutico en los ultimos anos, distan mucho de desaparecer a partir de la Kehre. Al contrario, en el marco conceptual de los tratados del Ereignis, el problema asume una nueva forma. La aclaracion de este problema exige, por un lado, desarrollar una critica historica de las «egologias» pertenecientes a la filosofia moderna, y por otro lado, replantear, a partir de la pregunta por «quienes somos», el sentido del ser humano y del Da-sein en la llamada historia del Ser. Son estos dos aspectos, intimamente ligados, los que queremos…
Short telomeres drive pessimistic judgement bias in zebrafish.
2021
The role of telomerase reverse transcriptase has been widely investigated in the contexts of ageing and age-related diseases. Interestingly, decreased telomerase activities (and accelerated telomere shortening) have also been reported in patients with emotion-related disorders, opening the possibility for subjective appraisal of stressful stimuli playing a key role in stress-driven telomere shortening. In fact, patients showing a pessimistic judgement bias have shorter telomeres. However, in humans the evidence for this is correlational and the causal directionality between pessimism and telomere shortening has not been established experimentally yet. We have developed and validated a judg…
Search for three body pion decays π+→l+νX
2021
The three body pion decays π+→l+νX(l=e,μ), where X is a weakly interacting neutral boson, were searched for using the full data set from the PIENU experiment. An improved limit on Γ(π+→e+νX)/Γ(π+→μ+νμ) in the mass range 0<mX<120 MeV/c2 and a first result for Γ(π+→μ+νX)/Γ(π+→μ+νμ) in the region 0<mX<33.9 MeV/c2 were obtained. The Majoron-neutrino coupling model was also constrained using the current experimental result of the π+→e+νe(γ) branching ratio.
Kinetics of Renal Function during Induction in Newly Diagnosed Multiple Myeloma: Results of Two Prospective Studies by the German Myeloma Study Group…
2021
Background: Preservation of kidney function in newly diagnosed (ND) multiple myeloma (MM) helps to prevent excess toxicity. Patients (pts) from two prospective trials were analyzed, provided postinduction (PInd) restaging was performed. Pts received three cycles with bortezomib (btz), cyclophosphamide, and dexamethasone (dex
Variaatio oppimisen osoittajana ja ohjaajana
2021
Arvioitu teos:
 Sirkku Lesonen: Valuing variability. Dynamic usage-based principles in the L2 development of four Finnish language learners. Groningen Dissertations in Linguistics 184. Groningen: Rijksuniversiteit Groningen 2020. 310 s. isbn 9789403426747. Saatavilla verkossa osoitteessa http://urn.fi/URN:ISBN:978-94-034-2675-4.
External imbalances from a GVAR perspective
2021
In this paper we study the drivers governing external disequilibria through a Global VAR (GVAR) analysis applied to a group of 24 countries during the period 1972-2017. The GVAR methodology is particularly well suited for our research question. First, it permits to measure the effects of both, domestic and foreign country-specific shocks. Second, it allows to analyze not only the long-run relationships, but also the dynamics through generalized impulse-response functions. Third, it enables to test many hypotheses from a macroeconomic perspective and the existence of spillovers. Our results show evidence of international financial integration in terms of the fulfillment of the real interest …
Micrometer-resolution reconstruction and analysis of whole mouse brain vasculature by synchrotron-based phase-contrast tomographic microscopy
2021
AbstractNervous tissue metabolism is mainly supported by the dense thread of blood vessels which mainly provides fast supplies of oxygen and glucose. Recently, the supplying role of the brain vascular system has been examined in major neurological conditions such as the Alzheimer’s and Parkinson’s diseases. However, to date, fast and reliable methods for the fine level microstructural extraction of whole brain vascular systems are still unavailable. We present a methodological framework suitable for reconstruction of the whole mouse brain cerebral microvasculature by X-ray tomography with the unprecedented pixel size of 0.65 μm. Our measurements suggest that the resolving power of the techn…
Progressive Recovery of a Marine Gastropod Community Following Atmospheric Nuclear Tests in French- Polynesia: A Socio-ecological Interpretation
2021
Aims: The way species-richness is accommodated and how species-abundance distribution is organized in a hierarchic pattern is central to community ecology. Yet, the process by which species-richness and species-abundances are progressively accommodated can hardly be monitored, in practice, at a sufficiently large spatial scale. Fortunately, the progressive recovery of marine communities, after their complete destruction by atmospheric nuclear tests, yet offered unique opportunity to monitor the full process of accommodation of increasing species-richness and the associated, transient development of strong interspecific competition, all along the process of recovery.
 Methods: Taking fu…
Methodological considerations for studies in sport and exercise science with women as participants: a working guide for standards of practice for res…
2021
AbstractUntil recently, there has been less demand for and interest in female-specific sport and exercise science data. As a result, the vast majority of high-quality sport and exercise science data have been derived from studies with men as participants, which reduces the application of these data due to the known physiological differences between the sexes, specifically with regard to reproductive endocrinology. Furthermore, a shortage of specialist knowledge on female physiology in the sport science community, coupled with a reluctance to effectively adapt experimental designs to incorporate female-specific considerations, such as the menstrual cycle, hormonal contraceptive use, pregnanc…
Possible Implications for Improved Osteogenesis? The Combination of Platelet-Rich Fibrin With Different Bone Substitute Materials
2021
Bone substitute materials (BSM) are widely used in oral regeneration, but sufficient angiogenesis is crucial for osteogenesis. The combination of BSM with autologous thrombocyte concentrations such as platelet-rich fibrin (PRF) may represent a clinical approach to overcome this limitation. This study analyzes the early influence on osteoblast (HOB) in vitro. Here, four different BSM (allogeneic, alloplastic, and two of xenogeneic origin) were combined with PRF. After the incubation with osteoblasts for 24 h, cell viability, migration, and proliferation were assessed. Next, marker of proliferation, migration, and differentiation were evaluated on gene and protein levels in comparison to the …
Impact of surface state on polyethylene glycol conformation confined inside a nanopore.
2021
Solid-state nanopores are a promising platform for characterizing proteins. In order to improve their lifetime and prevent fouling, Polyethylene Glycol (PEG) grafting is one of the most efficient and low-cost solutions. Different models to calculate the PEG thickness do not consider their interaction with the nanopore inner surface nor the effect of confinement. Here, we investigate by molecular dynamic simulation the PEG conformation inside a nanopore in the case of hydrophobic and hydrophilic nanopores. Our results reveal that the nanopore inner surface plays a role in the PEG organization and, thus, in the speed of the salt constituent. The resulting pair interaction between PEG and its …
Cloud droplet number closure for tropical convective clouds during the ACRIDICON–CHUVA campaign
2021
The main objective of the ACRIDICON-CHUVA (Aerosol, Cloud, Precipitation, and Radiation Interactions and Dynamics of Convective Cloud Systems–Cloud Processes of the Main Precipitation Systems in Brazil: A Contribution to Cloud Resolving Modeling and to the Global Precipitation measurements) campaign in September 2014 was the investigation of aerosol-cloud-interactions in the Amazon Basin. Cloud properties near cloud base of growing convective cumuli were characterized by cloud droplet size distribution measurements using a cloud combination probe (CCP) and a cloud and aerosol spectrometer (CAS-DPOL). In the current study, an adiabatic parcel model was used to perform cloud droplet number (N…
Mapping of the magnetic field to correct systematic effects in a neutron electric dipole moment experiment
2021
Experiments dedicated to the measurement of the electric dipole moment of the neutron require outstanding control of the magnetic-field uniformity. The neutron electric dipole moment (nEDM) experiment at the Paul Scherrer Institute uses a Hg199 co-magnetometer to precisely monitor temporal magnetic-field variations. This co-magnetometer, in the presence of field nonuniformity, is, however, responsible for the largest systematic effect of this measurement. To evaluate and correct that effect, offline measurements of the field nonuniformity were performed during mapping campaigns in 2013, 2014, and 2017. We present the results of these campaigns, and the improvement the correction of this eff…
tbg - a new file format for genomic data
2021
AbstractMotivationThe question of determining whether a Single-Nucleotide Polymorphism (SNP) or a variant in general leads to a change in the amino acid sequence of a protein coding gene is often a laborious and time-consuming challenge. Here, we introduce the tbg file format for storing genomic data and tbg-tools, a user-friendly toolbox for the faster analysis of SNPs. The file format stores information for each nucleotide in each gene, allowing to predict which change in the amino acid sequence will be caused by a variant in the nucleotide sequence. Our new tool therefore has the potential to make biological sense of the unprecedented amount of genome-wide genetic variation that research…