showing 36 of ~574560 from 574555 documents
Exposure and Risk Assessment of Hg, Cd, As, Tl, Se, and Mo in Women of Reproductive Age Using Urinary Biomonitoring
2021
The present study analyzed the exposure and risk assessment of 4 toxic (Hg, Cd, As, Tl) and 2 essential (Se, Mo) elements in 119 Spanish women of reproductive age. The focus was on the elements for which risk-based benchmark, biomonitoring equivalents, or health-related human biomonitoring values have already been established. All elements presented frequencies of detection of 100% (greater than the limit of detection), except for Cd (99%). The 95th percentile concentrations were, for the toxic metals, 358.37 µg/L (total As), 1.10 µg/L (Cd), 0.41 µg/L (Tl), and 3.03 µg/L (total Hg) and, for the essential elements, 68.95 µg/L (total Se) and 154.67 (Mo). We examined sociodemographic factors a…
Cultural Heritage Education in UNESCO Cultural Conventions
2021
The aim of the article is to analyse UNESCO conventions dealing with culture and assess the visibility and importance of cultural heritage education in these conventions and their implementation. First, it briefly presents the role of UNESCO in the area of culture and education, together with the UN Agenda 2030 and the challenges faced currently. Next, it discusses the existing UNESCO cultural conventions and their educational dimension with reference to the conventions’ provisions and aims. Each convention refers to education in the activities undertaken by States Parties, providing various tools and measures tailored to the scope of the convention. The article concludes that despite a lac…
New Features in the Electromagnetic Structure of the Neutron
2021
Here we present new results for the Born cross section and the effective form factor of the neutron at the center-of-mass energies ${\bf \sqrt{s}}$ between 2.0 and 3.08 GeV, using 18 data sets corresponding to an integrated luminosity of 647.9 pb${\bf ^{-1}}$ from e${\bf ^+}$e${\bf ^-}$ annihilation reactions collected at the BESIII experiment. The process $e^{+}e^{-}\to n\bar{n}$ is analyzed with three individual categories to improve the efficiency of $n\bar{n}$ reconstruction. The cross section of $e^{+}e^{-}\to n\bar{n}$ is measured at 18 c.m. energies where the best precision is 8.1\% at $\sqrt{s}=2.396$ GeV. The corresponding effective form factors are extracted under the assumption $…
false
2021
The COVID-19 pandemic has become a public health emergency of international concern, which may have affected lifestyle habits and mental health. Based on national health profile assessments, this study investigated perceived changes of lifestyle habits in response to the COVID-19 pandemic and associations between perceived lifestyle changes and mental health in Swedish working adults. Among 5599 individuals (50% women, 46.3 years), the majority reported no change (sitting 77%, daily physical activity 71%, exercise 69%, diet 87%, alcohol 90%, and smoking 97%) due to the pandemic. Changes were more pronounced during the first wave (April–June) compared to the second (October–December). Women,…
Grading investment diversification options in presence of non-historical financial information
2021
Modern portfolio theory deals with the problem of selecting a portfolio of financial assets such that the expected return is maximized for a given level of risk. The forecast of the expected individual assets’ returns and risk is usually based on their historical returns. In this work, we consider a situation in which the investor has non-historical additional information that is used for the forecast of the expected returns. This implies that there is no obvious statistical risk measure any more, and it poses the problem of selecting an adequate set of diversification constraints to mitigate the risk of the selected portfolio without losing the value of the non-statistical information owne…
Pattern of macrovascular invasion in hepatocellular carcinoma
2021
Background and aims: In patients with hepatocellular carcinoma (HCC), macrovascular invasion (MaVI) limits treatment options and decreases survival. Detailed data on the relationship between MaVI extension and patients' characteristics, and its impact on patients' outcome are limited. We evaluated the prevalence and extension of MaVI in a large cohort of consecutive HCC patients, analysing its association with liver disease and tumour characteristics, as well as with treatments performed and patients' survival. Methods: We analysed data of 4774 patients diagnosed with HCC recorded in the Italian Liver Cancer (ITA.LI.CA) database (2008-2018). Recursive partition analysis (RPA) was performed …
A new trifocal corneal inlay for presbyopia
2021
[EN] Corneal inlays (CIs) are the most recent surgical procedure for the treatment of presbyopia in patients who want complete independence from the use of glasses or contact lenses. Although refractive surgery in presbyopic patients is mostly performed in combination with cataract surgery, when the implantation of an intraocular lens is not necessary, the option of CIs has the advantage of being minimally invasive. Current designs of CIs are, either: small aperture devices, or refractive devices, however, both methods do not have good performance simultaneously at intermediate and near distances in eyes that are unable to accommodate. In the present study, we propose the first design of a …
Sémantique et représentation : l’articulation du discours
2021
International audience
LC-ESI/HRMS analysis of glucosinolates, oxylipins and phenols in Italian rocket salad (Diplotaxis erucoides subsp. erucoides (L.) DC.) and evaluation…
2021
BACKGROUND: This study investigated the chemical profile and biological activity of Diplotaxis erucoides subsp. erucoides (L.) DC. (Brassicaceae) collected in Sicily (Italy). RESULTS: Liquid chromatography coupled with electrospray ionization and high-resolution mass spectrometry (LC-ESI/HRMS) analysis of the ethanol extract revealed the presence of 42 compounds – glucosinolates, hydroxycinnamic acids, flavonoids, and oxylipins. The extract was tested for its antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic) acid (ABTS), ferric reducing ability power (FRAP), and β-carotene bleaching tests. Promising protection from lipid peroxi…
Increase in admissions for anorexia nervosa after lockdown measures: Focus on a children's neuropsychiatry unit.
2021
Meaning in Life Mediates Between Emotional Deregulation and Eating Disorders Psychopathology: A Research From the Meaning-Making Model of Eating Diso…
2021
Emotional dysregulation, age, gender, and obesity are transdiagnostic risk factors for the development and maintenance of eating disorders (EDs). Previous studies found that patients with ED had less meaning in life than the non-clinical population, and that meaning in life acted as a buffer in the course of ED; however, to the data, there are no studies about the mediator role of meaning in life in association between the emotional dysregulation and the ED psychopathology.Objective: To analyze the mediating role of meaning in life in the relationship between emotional dysregulation and the ED psychopathology in three samples with diverse risk factors for ED.Method: Sample 1, n = 153 underg…
Draft Genome Sequence and Biofilm Production of a Carbapenemase-Producing
2021
Rapid identification and characterization of multidrug-resistant Klebsiella pneumoniae strains is essential to diagnose severe infections in patients. In clinical routine practice, K. pneumoniae is frequently identified and characterized for outbreak investigation. Pulsed-field gel electrophoresis or multilocus sequence typing could be used, but, unfortunately, these methods are time-consuming, laborious, expensive, and do not provide any information about the presence of resistance and virulence genes. In recent years, the decreasing cost of next-generation sequencing and its easy use have led to it being considered a useful method, not only for outbreak surveillance but also for rapid ide…
Association of uric acid with kidney function and albuminuria: the Uric Acid Right for heArt Health (URRAH) Project
2021
Abstract Background Hyperuricemia is commonly observed in patients with chronic kidney disease (CKD). However, a better understanding of the relationship among uric acid (UA) values, glomerular filtration rate (GFR) and albuminuria may shed light on the mechanisms underlying the excess of cardiovascular mortality associated with both chronic kidney disease and hyperuricemia and lead to better risk stratification. Our main goal was to study the relationships between serum uric acid and kidney disease measures (namely estimated GFR [eGFR] and albuminuria) in a large cohort of individuals at cardiovascular risk from the URic acid Right for heArt Health (URRAH) Project database. Methods Clinica…
La soumission de l'arbitrage international à un régime protecteur du consommateur
2021
International audience; (Civ. 1re, 30 septembre 2020, n° 18-19.241, D. 2020. 2501, note D. Mouralis ; ibid. 2484, obs. T. Clay ; AJ contrat 2020. 485, obs. D. Mainguy ; RTD civ. 2020. 845, obs. L. Usunier ; Dalloz actualités, 19 octobre 2020, 1949, obs. J. Jourdan-Marques ; JCP 2020, 311, note M. de Fontmichel ; JDI 2020. 1307, note E. Gaillard)
Peut-on sélectionner les microbiomes comme on sélectionne les plantes cultivées ?
2021
International audience; L'évolution des écosystèmes est une question débattue sur un plan théorique. Mais l'absence de populations d'écosystèmes au sein desquelles il serait possible d'observer la sélection de certains variants conduit à une impasse : il n’existe pas de données empiriques pour valider ou invalider les hypothèses théoriques. Avec le développement des outils de séquençage massif, il devient possible de caractériser la structure des communautés microbiennes de nombreux microbiomes similaires (par exemple ceux des intestins humains ou des rhizosphères des plantes). On peut alors rechercher des indications d’une sélection naturelle ou mettre en place des expériences de sélection…
The triad hsp60-mirnas-extracellular vesicles in brain tumors: Assessing its components for understanding tumorigenesis and monitoring patients
2021
Brain tumors have a poor prognosis and progress must be made for developing efficacious treatments, but for this to occur their biology and interaction with the host must be elucidated beyond current knowledge. What has been learned from other tumors may be applied to study brain tumors, for example, the role of Hsp60, miRNAs, and extracellular vesicles (EVs) in the mechanisms of cell proliferation and dissemination, and resistance to immune attack and anticancer drugs. It has been established that Hsp60 increases in cancer cells, in which it occurs not only in the mitochondria but also in the cytosol and plasma-cell membrane and it is released in EVs into the extracellular space and in cir…
false
2021
Gammarid amphipods are a crucial link connecting primary producers with secondary consumers, but little is known about their nutritional ecology. Here we asked how starvation and subsequent feeding on different nutritional quality algae influences fatty acid retention, compound-specific isotopic carbon fractionation, and biosynthesis of ω-3 and ω-6 polyunsaturated fatty acids (PUFA) in the relict gammarid amphipod Pallaseopsis quadrispinosa. The fatty acid profiles of P. quadrispinosa closely matched with those of the dietary green algae after only seven days of refeeding, whereas fatty acid patterns of P. quadrispinosa were less consistent with those of the diatom diet. This was mainly due…
Sphincter damage during fistulotomy for perianal fistulae and its relationship with faecal incontinence.
2021
Abstract Background The length of sphincter which can be divided during fistulotomy for perianal fistula is unclear. The aim was to quantify sphincter damage during fistulotomy and determine the relationship between such damage with symptoms and severity of faecal incontinence and long-term quality of life (QOL). Methods A prospective cohort study was performed over a 2-year period. Patients with intersphincteric and mid to low transsphincteric perianal fistulas without risk factors for faecal incontinence were scheduled for fistulotomy. All patients underwent 3D endoanal ultrasound (3D-EAUS) pre-operatively and 8 weeks postoperatively. Measurements were taken of pre- and postoperative anal…
Chromogenic Chemodosimeter Based on Capped Silica Particles to Detect Spermine and Spermidine
2021
A new hybrid organic–inorganic material for sensing spermine (Spm) and spermidine (Spd) has been prepared and characterized. The material is based on MCM-41 particles functionalized with an N-hydroxysuccinimide derivative and loaded with Rhodamine 6G. The cargo is kept inside the porous material due to the formation of a double layer of organic matter. The inner layer is covalently bound to the silica particles, while the external layer is formed through hydrogen and hydrophobic interactions. The limits of detection determined by fluorimetric titration are 27 µM and 45 µM for Spm and Spd, respectively. The sensor remains silent in the presence of other biologically important amines and is a…
Aqua Mater: On the Meaning of the Theonym Betatun
2021
La aparición en el entorno del santuario tardoibérico de Las Atalayuelas (Fuerte del Rey – Torredelcampo, Jaén) de una inscripción en la que se documenta el teónimo ibérico Betatun abre nuevas perspectivas en el estudio de la religión ibérica. Con el presente artículo intentamos demostrar que en el nombre de la divinidad está implícito un elemento común que lo relacionaría con una serie de topónimos e hidrónimos, tanto antiguos como modernos, y que no es otro que el agua. The finding of an inscription containing the Iberian theonym Betatun in the surrounding area of the Late Iberian sanctuary in Las Atalayuelas site (Fuerte del Rey – Torredelcampo, Jaén) opens up new perspectives for the st…
Learning can be detrimental for a parasitic wasp
2021
Animals have evolved the capacity to learn, and the conventional view is that learning allows individuals to improve foraging decisions. The parasitoid Telenomus podisi has been shown to parasitize eggs of the exotic stink bug Halyomorpha halys at the same rate as eggs of its coevolved host, Podisus maculiventris, but the parasitoid cannot complete its development in the exotic species. We hypothesized that T. podisi learns to exploit cues from this non-coevolved species, thereby increasing unsuccessful parasitism rates. We conducted bioassays to compare the responses of naïve vs. experienced parasitoids on chemical footprints left by one of the two host species. Both naïve and experienced …
Existence of dynamical low-rank approximations to parabolic problems
2021
The existence and uniqueness of weak solutions to dynamical low-rank evolution problems for parabolic partial differential equations in two spatial dimensions is shown, covering also non-diagonal diffusion in the elliptic part. The proof is based on a variational time-stepping scheme on the low-rank manifold. Moreover, this scheme is shown to be closely related to practical methods for computing such low-rank evolutions.
Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries
2021
Importance: Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events. Objective: To evaluate the incidence and nature of adverse peri-intubation events and to assess current practice of intubation in critically ill patients. Design, Setting, and Participants: The International Observational Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients (INTUBE) study was an international, multicenter, prospective cohort study involving consecutive critically ill patients undergoing tracheal intubation in the intensive care units (ICUs…
Deep Learning for fully automatic detection, segmentation, and Gleason Grade estimation of prostate cancer in multiparametric Magnetic Resonance Imag…
2021
The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of patients for confirmation biopsy. However, analyzing these images is complex even for experts, hence opening an opportunity for computer-aided diagnosis systems to seize. This paper proposes a fully automatic system based on Deep Learning that takes a prostate mpMRI from a PCa-suspect patient and, by leveraging the Retina U-Net detection framework, locates PCa lesions, segments them, and predicts their most likely Gleason grade group (GGG). It uses 490 mp…
On the Role of Perception: Understanding Stakeholders’ Collaboration in Natural Resources Management through the Evolutionary Theory of Innovation
2021
Natural resources management deals with highly complex socioecological systems. This complexity raises a conundrum, since wide-ranging knowledge from different sources and types is needed, but at the same time none of these types of knowledge is able by itself to provide the basis for a viable productive system, and mismatches between the two of them are common. Therefore, a growing body of literature has examined the integration of different types of knowledge in fisheries management. In this paper, we aim to contribute to this ongoing debate by integrating the evolutionary theory of innovation—and specifically the concept of proximity—and the theory of perception. We set up a theoretical …
La jurisprudencia existente acerca de la indumentaria del trabajador y otros elementos que afectan a su aspecto e imagen externa durante el trabajo
2021
Partiendo de la doctrina del “equilibrio de derechos” del Tribunal Constitucional sobre la solución de los conflictos de concurrencia entre derechos constitucionales, se analiza la jurisprudencia de los principales Tribunales acerca del conflicto entre la libertad de empresa y el derecho a la propia imagen del trabajador en relación la indumentaria de éste en el trabajo.
Morphology, Genetics and Biology of Pterochloroides persicae Cholodkovsky (Hemiptera: Lachninae) and Their Effect on Pauesia antennata Mukerji (Hymen…
2021
Pauesia antennata Mukerji is a specific parasitoid of the brown peach aphid Pterochloroides persicae Cholodkovsky which causes severe damage on almond and peach in Tunisia. To control this pest, P. antennata was collected from Iran, introduced to Tunisia in 2011 and some of their biological parameters were studied in laboratory conditions. Therefore, in orchard, aphid population and sites/zones of Tunisia and aphid behaviour impact on the parasitoid have not been studied. Morphometric measurements, molecular analysis of P. persicae specimens collected from two Tunisian sites [(Akouda-Sousse (Site 1), Sfax (Site 2)] were studied and compared and aphid behaviour versus P. antennata was follow…
Spatial distribution, contamination assessment and potential ecological risk of some trace metals in the surface sediments of the Gulf of Tunis, Nort…
2021
To evaluate the trace metals contamination status in the Gulf of Tunis, forty one sediment samples were analyzed using different approaches. According to certain contamination and ecological risk indices (Contamination Factor, Geoaccumulation index and Ecological risk index), Hg has the highest contamination level while pollution by Ni, Pb, Cd and Cr was absent. The highest concentrations of trace metals were found in sediments collected from the offshore and coastal areas located opposite the main exchange points with the gulf particularly, the Mejerda and Meliane Rivers, the Khalij Channel, Ghar El Melh and El Malah lagoons, Tunis Lake and Sebkhat Ariana. However, further ecological indic…
Citocentrifugación como un método adicional para estudiar celomitos de equinodermos: un enfoque comparativo que combina células vivas, preparaciones …
2021
Abstract Introduction: Echinoderm coelomocytes have traditionally been investigated through a morphological approach using light microscopy, which relies on the idea of constant cell shape as a stable character. However, this can be affected by biotic or abiotic conditions. Objective: To analyze if the consistency in cell morphology offered by the cytocentrifugation method, might be used as a convenient tool to study echinoderm coelomocytes. Methods: Cells of Echinaster (Othilia) brasiliensis (Asteroidea), Holothuria (Holothuria) tubulosa (Holothuroidea), Eucidaris tribuloides, Arbacia lixula, Lytechinus variegatus, and Echinometra lucunter (Echinoidea) were spread on microscope slides by c…
A Single-Center Experience with Lung Transplants During the COVID-19 Pandemic
2021
BACKGROUND This single-center study analyzed distinctions between lung transplants performed in the Department of Cardiac and Vascular surgery of the University Clinical Center in Gdansk, Poland before and during the COVID-19 pandemic. MATERIAL AND METHODS There were 189 patients who underwent the qualification procedure to lung transplantation in the Department of Cardiac and Vascular Surgery of the University Clinical Center in Gdansk, Poland in the years 2019 and 2020. The control group consisted of 12 patients transplanted in 2019, and the study group consisted of 16 patients transplanted in 2020. RESULTS During 2019, the qualification process was performed in 102 patients with pulmonar…
(Re)descubriendo el control de convencionalidad: ¿activismo o autocontención judicial?
2021
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The role of social media in the rise of right-wing populism in Finland
2021
Right-wing populism is typically entangled with xenophobic nationalism and neo-conservatism, which often usher in racism and misogyny. In this chapter, the authors take Finland as a case study to examine the role of media technology in the rise of right-wing populism. They demonstrate the strengthening of the far-right ideology on and through social media from the beginning of 2010s. It focuses on the mediated construction of two entangled ideologies in the right-wing populist movement racism and misogyny. In early spring 2020, the debate about Turkey opening its EU border to refugees made Jussi Halla-aho eagerly participate in this discussion in the parliament and on Twitter now as the cha…
Right inferior frontal gyrus implements motor inhibitory control via beta-band oscillations in humans
2021
Motor inhibitory control implemented as response inhibition is an essential cognitive function required to dynamically adapt to rapidly changing environments. Despite over a decade of research on the neural mechanisms of response inhibition, it remains unclear, how exactly response inhibition is initiated and implemented. Using a multimodal MEG/fMRI approach in 59 subjects, our results reliably reveal that response inhibition is initiated by the right inferior frontal gyrus (rIFG) as a form of attention-independent top-down control that involves the modulation of beta-band activity. Furthermore, stopping performance was predicted by beta-band power, and beta-band connectivity was directed f…
Mass measurements of As, Se, and Br nuclei, and their implication on the proton-neutron interaction strength toward the N=Z line
2021
Mass measurements of the $^{69}$As, $^{70,71}$Se and $^{71}$Br isotopes, produced via fragmentation of a $^{124}$Xe primary beam at the FRS at GSI, have been performed with the multiple-reflection time-of-flight mass spectrometer (MR-TOF-MS) of the FRS Ion Catcher with an unprecedented mass resolving power of almost 1,000,000. For the $^{69}$As isotope, this is the first direct mass measurement. A mass uncertainty of 22 keV was achieved with only 10 events. For the $^{70}$Se isotope, a mass uncertainty of 2.6 keV was obtained, corresponding to a relative accuracy of $\delta$m/m = 4.0$\times 10^{-8}$, with less than 500 events. The masses of the $^{71}$Se and $^{71}$Br isotopes were measured…
Familias diversas. Ejemplos cinematográficos Disney de nueve estructuras familiares
2021
espanolUna de las pretensiones de la Educacion Infantil en el territorio nacional consiste en desarrollar integralmente al colectivo infantil, otorgandole las herramientas clave para desenvolverse en la sociedad a la que pertenece como individuo. Para ello, la alfabetizacion audiovisual resulta indispensable, ensenarles a decodificar los mensajes que reciben de la cultura visual de su entorno. Entre la pluralidad de opciones destaca la cinematografia Disney como ejemplo significativo para el alumnado de esta etapa educativa. Partiendo de la coleccion “Los clasicos” Disney (1937-2016) se realiza una investigacion de tipo mixto para manifestar la presencia de los diferentes tipos de estructur…
Copper-hydride nanoclusters with enhanced stability by N-heterocyclic carbenes
2021
AbstractCopper-hydrides have been intensively studied for a long time due to their utilization in a variety of technologically important chemical transformations. Nevertheless, poor stability of the species severely hinders its isolation, storage and operation, which is worse for nano-sized ones. We report here an unprecedented strategy to access to ultrastable copper-hydride nanoclusters (NCs), namely, using bidentate N-heterocyclic carbenes as stabilizing ligands in addition to thiolates. In this work, a simple synthetic protocol was developed to synthesize the first large copper-hydride nanoclusters (NCs) stabilized by N-heterocyclic carbenes (NHCs). The NC, with the formula of Cu31(RS)2…