showing 36 of ~574560 from 574555 documents
De la psychomécanique du langage à la néoténie linguistique : épistémologie, transfert de concepts et emprunts terminologiques
2021
International audience; No abstract
Fluocinolone acetonide vitreous insert for chronic diabetic macular oedema: a systematic review with meta-analysis of real-world experience
2021
AbstractWe conducted a meta-analysis of real-world studies on the 0.19 mg Fluocinolone Acetonide (FAc) intravitreal implant for chronic diabetic macular oedema (DMO), comparing these findings with the Fluocinolone Acetonide for Diabetic Macular Edema (FAME) study. The primary outcome was mean change of best corrected visual acuity (BCVA) at 24 months. Secondary outcomes were 36-month mean BCVA, mean central macular thickness (CMT) change, rates of eyes receiving supplementary intravitreal therapy, cataract surgery, intraocular pressure (IOP)-lowering drops and glaucoma surgery. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Nine real-world studies were included.…
Validation of monocyte distribution width decisional cutoff for sepsis detection in the acute setting
2021
not available
Labor and product market reforms and external Imbalances: Evidence from advanced economies
2021
We explore the impact of major labor and product market reforms on current account dynamics using a new “narrative” database of major changes in employment protection for regular workers and product market regulation for non-manufacturing industries covering 26 advanced economies over the past four decades. Our main finding is that product market deregulation is associated with a weakening of the current account, while labor market deregulation is associated with an improvement. These effects are transitory and driven by both saving and investment responses. Labor and product market reforms both have a more positive impact on the current account balance when implemented under weak macroecon…
Dimension of the isometry group in three-dimensional Riemannian spaces
2021
The necessary and sufficient conditions for a three-dimensional Riemannian metric to admit a group of isometries of dimension $r$ acting on s-dimensional orbits are obtained. These conditions are Intrinsic, Deductive, Explicit and ALgorithmic and they offer an IDEAL labeling that improves previously known invariant studies.
2V91
2021
Sekcija “Indivīds un vara Baltijas kultūrtelpā”: tēžu krājums
2021
Krājumā apkopotas 2021. gada 26. februārī Latvijas Universitātes 79. Starptautiskās zinātniskās konferences ietvaros LU Latvijas vēstures institūta organizētās sekcijas “Indivīds un vara Baltijas kultūrtelpā” nolasīto referātu tēzes. Tajās aplūkota indivīda un varas mijiedarbība sociologu un vēsturnieku skatījumā visai plašā laika diapazonā – no 13. gs. līdz 20. gs. Tēzēs ietvertās atziņas balstītas padziļinātās rakstīto avotu studijās, ietver jaunākās zinātniskās atziņas pētāmajā problemātikā un reflektē par atsevišķu faktu interpretāciju plašsaziņas līdzekļos. Konferencē nolasīti 10 referāti, autori – LU LVI un LU FSI vadošie pētnieki un pētnieki.
Increasing the Circularity of asphalt mixtures: Integrated Sustainability and Circularity Assessment as a progress monitoring tool towards more Circu…
2021
Sustainability and Circular Economy (CE) are two concepts that lately have been profoundly linked to each other. The road engineering industry has gradually been adapting practices that are considered both circular and sustainable. However, not all of these practices entirely consider the whole life environmental and circularity assessment and implications of asphalt mixtures.; which in turn leads to doubtfully circular and sustainable approaches. For this reason in this thesis, after analysing the ways that National Road Authorities implement and communicate CE through questionnaires and web searches, a Material Circularity Index quantifying framework, based on the proposed methodology of …
A unified vegetation index for quantifying the terrestrial biosphere
2021
[EN] Empirical vegetation indices derived from spectral reflectance data are widely used in remote sensing of the biosphere, as they represent robust proxies for canopy structure, leaf pigment content, and, subsequently, plant photosynthetic potential. Here, we generalize the broad family of commonly used vegetation indices by exploiting all higher-order relations between the spectral channels involved. This results in a higher sensitivity to vegetation biophysical and physiological parameters. The presented nonlinear generalization of the celebrated normalized difference vegetation index (NDVI) consistently improves accuracy in monitoring key parameters, such as leaf area index, gross prim…
A comparison of semiparametric approaches to evaluate composite endpoints in heart failure trials
2021
In heart failure trials efficacy is usually proven by a composite endpoint including cardiovascular death (CVD) and recurrent heart failure hospitalisations (HFH), evaluated with time-to-first-event analysis based on a Cox model. As a considerable fraction of events is ignored that way, recurrent event[for full text, please go to the a.m. URL]
Host-directed therapies for COVID-19
2021
Purpose of review Severe acute respiratory syndrome coronavirus-2-induced hyperinflammation is a major cause of death or end-organ dysfunction in COVID-19 patients. We review adjunct host-directed therapies (HDTs) for COVID-19 management. Recent findings The use of umbilical cord-derived mesenchymal stem cells as HDT for COVID-19 has been shown to be safe in phase 1 and 2 trials. Trials of anti-interleukin-6 receptor antibodies show promising mortality benefit in hospitalized COVID-19 patients. Repurposed drugs and monoclonal antibodies targeting specific cytokines acting on different aspects of the pro- and anti-inflammatory cascades are under evaluation. Summary A range of HDTs shows prom…
Crystal structure and Hirshfeld surface analysis of poly[[bis[μ4-N,N′-(1,3,5-oxadiazinane-3,5-diyl)bis(carbamoylmethanoato)]nickel(II)tetrapotassium]…
2021
The complex nickel(II) anion comprises a pseudomacrocyclic hydrazide-based ligand with an L shape. In the crystal, such anions are connected with the potassium cations and the water solvent molecules, forming a three-dimensional polymeric framework, which is stabilized by an extensive system of hydrogen bonds.
Inwazyjny rak piersi w ektopowej tkance gruczołowej zlokalizowanej w dole pachowym. Opis przypadku
2021
Breast cancer is the most commonly diagnosed malignancy in women in Poland. Rare, unusual forms of breast cancer remain a diagnostic problem. The incidence of ectopic breast glandular tissue in the general population varies between 0.4 and 6%. The same abnormalities and diseases as in the anatomical mammary gland may develop in this tissue. Breast cancer may develop as well. We present the case of a 36-year-old woman, who went to the doctor because of a nodule in the right armpit presented for 2 years. The patient was referred to a surgeon with suspicion of an epidermal cyst. The lesion was surgically removed and in the histopathological examination, the diagnose was: invasive breast cancer…
Influence of Wind on Suspended Matter in the Water of the Albufera of Valencia (Spain)
2021
Wind is one of the factors that has a great influence on suspended matter in lakes, especially in shallow lagoons. In order to know how wind affects the water in Albufera of Valencia, a shallow coastal lagoon, the measured variables of turbidity and transparency have been correlated with the estimates by processing Sentinel-2 satellite images with the Sen2Cor processor. Data from four years of study show that most of them are light to gentle easterly breezes and moderate to fresh westerly breezes. The results obtained show significant correlations between the measured variables and those obtained from the satellite images for total suspended matter and water transparency and with the averag…
A computational approximation for the solution of retarded functional differential equations and their applications to science and engineering
2021
<p style='text-indent:20px;'>Delay differential equations are of great importance in science, engineering, medicine and biological models. These type of models include time delay phenomena which is helpful for characterising the real-world applications in machine learning, mechanics, economics, electrodynamics and so on. Besides, special classes of functional differential equations have been investigated in many researches. In this study, a numerical investigation of retarded type of these models together with initial conditions are introduced. The technique is based on a polynomial approach along with collocation points which maintains an approximated solutions to the problem. Beside…
Radiotherapy before or during androgen-deprivation therapy does not blunt the exercise-induced body composition protective effects in prostate cancer…
2021
Background Androgen deprivation therapy (ADT) contributes to lean mass loss and adiposity increases in prostate cancer patients. Radiotherapy during ADT might act synergistically and further worsen body composition. Previous investigations have shown that resistance training is an effective method of preserving body composition during ADT, however, most have not accounted for direct or indirect effects of other therapies, such as radiotherapy. Therefore, the purpose of this study was to examine training adaptations of the tissue composition in patients receiving radiation therapy (RT) prior or during ADT. Methods Analyses were performed by combining data from two previous trials for a total…
Essays on Corruption
2021
Paper III and Paper IV is not published yet. Corruption is blamed for reductions in operational efficiency, information asymmetry, limited income distribution, policy failure, and weak economic growth and development. Corruption can originate from either the “demand-side” (the recipients of the bribe) or the “supply-side” (the givers of the bribe). This double edge effect of corruption on the economy and society makes it a multidisciplinary subject and phenomenon. Thus, scholars from different fields and disciplines, such as finance, banking, economics, accounting, law, foreign aid, and international business, examined and analyzed corruption as a multidisciplinary subject. In this disserta…
Shotgun Proteomics of Isolated Urinary Extracellular Vesicles for Investigating Respiratory Impedance in Healthy Preschoolers
2021
Urine proteomic applications in children suggested their potential in discriminating between healthy subjects from those with respiratory diseases. The aim of the current study was to combine protein fractionation, by urinary extracellular vesicle isolation, and proteomics analysis in order to establish whether different patterns of respiratory impedance in healthy preschoolers can be characterized from a protein fingerprint. Twenty-one 3–5-yr-old healthy children, representative of 66 recruited subjects, were selected: 12 late preterm (LP) and 9 full-term (T) born. Children underwent measurement of respiratory impedance through Forced Oscillation Technique (FOT) and no significant differen…
false
2021
Abstract Background Individuals with cerebral palsy (CP) have problems in everyday tasks such as walking and climbing stairs due to a combination of neuromuscular impairments such as spasticity, muscle weakness, reduced joint flexibility and poor coordination. Development of evidence-based interventions are in pivotal role in the development of better targeted rehabilitation of CP, and thus in maintaining their motor function and wellbeing. Our aim is to investigate the efficacy of an individually tailored, multifaceted exercise intervention (EXECP) in children and young adults with CP. EXECP is composed of strength, flexibility and gait training. Furthermore, this study aims to verify the …
Ideologies as false communicative practices
2021
Against common understanding of ideology as being a specific form of knowledge or cognition, lately there is a rediscovering of the notion of ideology as practice. In these approaches, ideology is ...
More comprehensive proprioceptive stimulation of the hand amplifies its cortical processing
2021
Corticokinematic coherence (CKC) quantifies the phase coupling between limb kinematics and cortical neurophysiological signals reflecting proprioceptive feedback to the primary sensorimotor (SM1) cortex. We studied whether the CKC strength or cortical source location differs between proprioceptive stimulation (i.e., actuator-evoked movements) of right-hand digits (index, middle, ring, and little). Twenty-one volunteers participated in magnetoencephalography measurements during which three conditions were tested: 1) simultaneous stimulation of all four fingers at the same frequency, 2) stimulation of each finger separately at the same frequency, and 3) simultaneous stimulation of the fingers…
A remark on two notions of flatness for sets in the Euclidean space
2021
In this note we compare two ways of measuring the $n$-dimensional "flatness" of a set $S\subset \mathbb{R}^d$, where $n\in \mathbb{N}$ and $d>n$. The first one is to consider the classical Reifenberg-flat numbers $\alpha(x,r)$ ($x \in S$, $r>0$), which measure the minimal scaling-invariant Hausdorff distances in $B_r(x)$ between $S$ and $n$-dimensional affine subspaces of $\mathbb{R}^d$. The second is an `intrinsic' approach in which we view the same set $S$ as a metric space (endowed with the induced Euclidean distance). Then we consider numbers ${\sf a}(x,r)$'s, that are the scaling-invariant Gromov-Hausdorff distances between balls centered at $x$ of radius $r$ in $S$ and the $n$-dimensi…
Recyclable and Light-Adaptive Vitrimer-Based Nacre-Mimetic Nanocomposites.
2021
Nacre's natural design consists of a perfect hierarchical assembly that resembles a brick-and-mortar structure with synergistic stiffness and toughness. The field of bioinspired materials often provides attractive architecture and engineering pathways which allow to explore outstanding property areas. However, the study of nacre-mimetic materials should not be limited to the design of its architecture but ought to include the understanding, operation, and improvement of internal interactions between their components. Here, we introduce a vitrimer prepolymer system that, once integrated into the nacre-mimetic nanocomposites, cures and cross-links with the presence of Lewis acid catalyst and …
Residence Time Analysis in the Albufera of Valencia, a Mediterranean Coastal Lagoon, Spain
2021
The Albufera of Valencia is a coastal lagoon located in the western area of the Mediterranean Sea, in the Iberian Peninsula. It has an area of 23.1 km2 and an average depth of only 1 m, with a maximum depth of 1.6 m. This lagoon is the remnants of an original and more extensive wetland of about 220 km2 which is now mostly dedicated to rice cultivation. Surface water is supplied through several main and many secondary canals for a total of 64 water entry points and three exit points to the sea. It is difficult to evaluate the residence time due to the lack of reliable measurements of the inflow or outflow, as well as continuous measurements. Between 1988 and 2018, several procedures were use…
Phonons of hexagonal BN under pressure: Effects of isotopic composition
2021
Raman scattering experiments on isotopically enriched hexagonal boron nitride have been performed under pressure up to 11 GPa at room temperature. The sublinear increase of the Raman-active E2g mode frequencies has been characterized. The pressure behavior has been analyzed by means of a bond-stiffness–bond-length scaling parameter γ which takes into consideration the vast differences in a- and c-axis compressibilities. The interlayer shear mode exhibits a γ parameter similar to that of graphite, and the mode frequency in isotopically pure samples separates faster at low pressures as a result of van der Waals interactions. Because of the extremely low a-axis compressibility, the intralayer …
Characters and generation of Sylow 2-subgroups
2021
Form-factor-independent test of lepton universality in semileptonic heavy meson and baryon decays
2021
In the semileptonic decays of heavy mesons and baryons the lepton-mass dependence factors out in the quadratic $\cos^2\theta$ coefficient of the differential $\cos\theta$ distribution. We call the corresponding normalized coefficient the convexity parameter. This observation opens the path to a test of lepton universality in semileptonic heavy meson and baryon decays that is independent of form-factor effects. By projecting out the quadratic rate coefficient, dividing out the lepton-mass-dependent factor and restricting the phase space integration to the $\tau$ lepton phase space, one can define optimized partial rates which, in the Standard Model, are the same for all three $(e,\mu,\tau)$ …
The four spheres of value co-creation in humanitarian professional services
2021
PurposeThe study focuses on the value co-creation processes in humanitarian professional services provision, analysing the key enabling factors of beneficiaries' participation, involved in long-term integration programmes (L-TIPs).Design/methodology/approachThrough an in-depth case study, the research looks at the practices of value co-creation in humanitarian professional services, considering both the perspectives of the professional service provider and beneficiary.FindingsIn professional services beneficiary's participation affects the success of the L-TIPs outcomes. Participation's enablers can be classified into four different spheres, each belonging to different elements of professio…
Link between cardiovascular disease and the risk of falling: a comprehensive review of the evidence.
2021
Falls are associated with increased morbidity and mortality, rising hospital readmission rates, decreased patient independence, and strained healthcare resources. In aged populations and individuals with multimorbidity, cardiovascular conditions may contribute towards an increased propensity to fall. The prevalence of cardiovascular conditions generally increases with age, and understanding potential fall risk factors may help to minimize the risk of falls and develop preventive interventions. Acting on even one such risk factor or introducing an appropriate intervention may reduce the overall propensity for a patient to fall. Further prevention strategies primed towards cardiovascular ailm…
The study of bone healing after endodontic microsurgery using cone beam computed tomography: A retrospective cohort study.
2021
The main aims of this study were to evaluate mean volume reduction, radiographic healing rate and healing outcome two years after endodontic microsurgery. The effects of certain preoperative clinical factors upon preoperative volume, volumetric changes and healing outcome were also studied.A clinical database was searched for patients who had undergone endodontic microsurgery and with the availability of a cone beam computed tomography (CBCT) scan preoperatively and after a control period. Volumetric analysis of the periapical area was made to assess volumetric reduction. The modified Penn 3D criteria were applied. The relationship between preoperative volume, volumetric reduction and heali…
Diagnostic and Therapeutic Approach to Sleep Disorders, High Blood Pressure and Cardiovascular Diseases. A Consensus Document by the Italian Society …
2021
Hypertension is a major contributor to fatal/nonfatal cardiovascular diseases, and timely identification and appropriate management of factors affecting hypertension and its control are mandatory public health issues. By inducing neurohormonal alterations and metabolic impairment, sleep disorders have an impact on a variety of cardiovascular risk factors, including hypertension, and ultimately increase the risk of cardiovascular events. There is evidence that qualitative and quantitative sleep disorders are associated with resistant hypertension and with impaired circadian blood pressure variations. However, sleep disturbances are often unrecognized, or heterogeneity exists in their managem…
An approach to the Venturi effect by historical instruments
2021
Student understanding of the laws that describe the flow of a fluid is often hampered by a defective knowledge of basic classical mechanics (kinematics, statics, dynamics, and conservation laws) and by wrong common-sense ideas about quantities related to fluids, such as velocity and pressure. A pedagogical discussion about the Venturi effect, based on experiments inspired by historical instruments, may be an effective way to introduce students to these laws. In this paper, we discuss an approach to the understanding of the Venturi effect based on the study of historical instruments and on simple experiments. In particular, after a presentation of the Venturi effect, also from a historical p…
Validating the Spanish version of the aggression scale in adolescents
2021
The Scale of Physical and Verbal Aggressiveness has been an instrument widely used in the scientific literature to measure physical and verbal aggressiveness, both in children and adolescents as we...
Surrogate models for the compressive strength mapping of cement mortar materials
2021
Despite the extensive use of mortar materials in constructions over the last decades, there is not yet a robust quantitative method available in the literature, which can reliably predict their strength based on the mix components. This limitation is attributed to the highly nonlinear relation between the mortar’s compressive strength and the mixed components. In this paper, the application of artificial intelligence techniques for predicting the compressive strength of mortars is investigated. Specifically, Levenberg–Marquardt, biogeography-based optimization, and invasive weed optimization algorithms are used for this purpose (based on experimental data available in the literature). The c…
Méthodes de lagrangien et de Nitsche pour l'approximation numérique des conditions de contact avec frottement
2021
L'objectif de ce chapitre est de faire une présentation détaillée de développements récents sur l'approximation des conditions de contact des solides déformables en petites et grandes déformations. Les principes de base des méthodes de lagrangien, lagrangien augmenté, lagrangien stabilisé, de pénalité et de Nitsche sont exposés. Les liens étroits existants entre la méthode de Nitsche, le lagrangien stabilisé et le lagrangien augmenté sont alors analysés.
Psychological and metabolic risk factors in older adults with a previous history of eating disorder: A cross-sectional study from the Predimed-Plus s…
2021
Goals To explore affective and cognitive status, later in life, in individuals with and without previous history of eating disorder (ED), and also its association with higher risk for metabolic syndrome (MetS) symptomatology. Methods A cross-sectional analysis of 6756 adults, aged 55-75 years with overweight/obesity and MetS participating in the Predimed-Plus study was conducted. Participants completed self-reported questionnaires to examine lifetime history of ED, according to DSM-5 criteria, and other psychopathological and neurocognitive factors. Anthropometric and metabolic measurements were also collected. Results Of the whole sample, 24 individuals (0.35%) reported a previous history …