showing 36 of ~574560 from 574555 documents
The humanities are not our patient
2021
When inviting contributions to a special issue of this journal titled ‘Management Learning and the Unsettled Humanities’ the guest editors did not simply encourage contributors to explore possibilities ‘for reciprocal integration’ between the two realms. Stressing that ‘the humanities . . . [are] facing a complex crisis on their own’, they stated that ‘the humanities . . . need to be enriched, nuanced, and critiqued through . . . the ideas and perspectives of organisational research’. While we may agree that all is not well in the humanities and share their scepticism towards ‘just prescribing the value of the humanities to ameliorate the ills of management education’, we are less confiden…
Micro-photoluminescence of Carbon Dots Deposited on Twisted Double-Layer Graphene Grown by Chemical Vapor Deposition
2021
Carbon-based nanomaterials, such as carbon dots (CDs) and graphene (Gr), feature outstanding optical and electronic properties. Hence, their integration in optoelectronic and photonic devices is easier thanks to their low dimensionality and offers the possibility to reach high-quality performances. In this context, the combination of CDs and Gr into new nanocomposite materials CDs/Gr can further improve their optoelectronic properties and eventually create new ones, paving the way for the development of advanced carbon nanotechnology. In this work, we have thoroughly investigated the structural and emission properties of CDs deposited on single-layer and bilayer graphene lying on a SiO2/Si …
'Not as safe as I believed': Differences in perceived and self-reported cycling behavior between riders and non-riders
2021
Cycling behavior remains a key issue for explaining several traffic causalities occurring every day. However, recent studies have shown how the assessment of the own safety-related behaviors on the road may substantially differ from how third parties assess them. Thus, the aim of this study was to evaluate the differences between cyclists’ self-reported behavior and the proxy-reported behavior that other (non-cyclist) road users perceive from bike riders. For this purpose, this study used data from two samples: (i) 1064 cyclists (M = 32.83 years) answering the Cycling Behavior Questionnaire—CBQ, and (ii) 1070 non-cyclists (M = 30.83 years) answering an adapted version of the CBQ for externa…
Kinerja Mesin Ekstraksi Pati Sagu Tipe Vertikal Stirrer Rotary Blade Menggunakan Saringan 100 mesh pada Berbagai Durasi Waktu Ekstraksi
2021
Tujuan penelitian ini adalah menguji kinerja mesin ekstraksi pati sagu tipe vertical stirrer rotary blade menggunakan saringan 100 mesh pada berbagai durasi waktu ekstraksi. Pengujian kinerja mesin dilakukan pada empat level durasi waktu ekstraksi yaitu 10, 15, 20 dan 25 menit. Evaluasi kinerja dilakukan dengan mengukur parameter (1) rendemen pati, (2) hasil pati, (3) kapasitas ekstraksi dan (4) kehilangan pati pada ampas. Hasil uji kinerja menunjukkan bahwa semakin tinggi durasi waktu ekstraksi, semakin tinggi rendemen pati dan hasil pati, namun kapasitas ekstraksi, dan persentase pati pada ampas semakin rendah. Berdasarkan parameter hasil pati tertinggi dan persentase kehilangan pati pa…
Renal outcomes and blood pressure patterns in diabetic and nondiabetic individuals at high cardiovascular risk
2021
Background Diabetes and hypertension are risk factors for renal and cardiovascular outcomes. Data on the association of achieved blood pressure (BP) with renal outcomes in patients with and without diabetes are sparse. We investigated the association of achieved SBP, DBP with renal outcomes and urinary albumin excretion (UAE) in people with vascular disease. Methods In this pooled analysis, we assessed renal outcome data from high-risk patients aged 55 years or older with a history of cardiovascular disease, 70% of whom had hypertension, randomized to The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial and to Telmisartan Randomized Assessment Study in ACE In…
Bilateral Ultrathin Descemet’s Stripping Automated Endothelial Keratoplasty vs. Bilateral Penetrating Keratoplasty in Fuchs’ Dystrophy: Corneal Highe…
2021
Background and Objectives: The objective of this paper is to compare the visual outcomes and quality of life (QoL) after bilateral ultrathin Descemet’s stripping automated endothelial keratoplasty (UT-DSAEK) with bilateral penetrating keratoplasty (PK) for Fuchs’ endothelial dystrophy (FED). Materials and Methods: Retrospective comparative cohort study, including 11 patients with FED who underwent bilateral PK and 13 patients with FED who underwent bilateral UT-DSAEK. All patients were already pseudophakic or had undergone a combined cataract procedure. The main outcomes were corrected distance visual acuity (CDVA) corneal higher-order aberrations (HOAs), contrast sensitivity (CS) and quali…
Role of acute social stress in the rewarding effects of MDMA in adolescent mice
2021
Drug use among adolescents is a serious problem in our society, as some individuals develop dependence and addiction. MDMA/Esctasy is one of the most typically used substances by this age group. It is well known that environmental factors can alter the rewarding properties of drugs and the propensity to drug-related disorders. In this sense, exposure to social stress induces long-term effects in mice, enhancing the rewarding effects of MDMA in the conditioned place preference (CPP) paradigm. On the other hand, previous research has not provided conclusive results regarding the short-term effects of social defeat on MDMA reward in adolescent animals, probably due to the use of very low or ve…
Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography
2021
ABSTRACTHuman organs are complex, three-dimensional and multiscale systems. Spatially mapping the human body down through its hierarchy, from entire organs to their individual functional units and specialised cells, is a major obstacle to fully understanding health and disease. To meet this challenge, we developed hierarchical phase-contrast tomography (HiP-CT), an X-ray phase propagation technique utilising the European Synchrotron Radiation Facility’s Extremely Brilliant Source: the world’s first high-energy 4th generation X-ray source. HiP-CT enabled three-dimensional and non-destructive imaging at near-micron resolution in soft tissues at one hundred thousand times the voxel size whilst…
A Measure of Concurrent Neural Firing Activity Based on Mutual Information
2021
Multiple methods have been developed in an attempt to quantify stimulus-induced neural coordination and to understand internal coordination of neuronal responses by examining the synchronization phenomena in neural discharge patterns. In this work we propose a novel approach to estimate the degree of concomitant firing between two neural units, based on a modified form of mutual information (MI) applied to a two-state representation of the firing activity. The binary profile of each single unit unfolds its discharge activity in time by decomposition into the state of neural quiescence/low activity and state of moderate firing/bursting. Then, the MI computed between the two binary streams is…
No road is long with good company. What factors affect Ph.D. student’s satisfaction with their supervisor?
2021
PurposeHow frequently may be advisable for a supervisor to meet a PhD student? Are PhD students more satisfied if supervised by someone of the same gender, nationality or with common research interests? Thus far, we lack quantitative evidence regarding similar crucial aspects of managing PhD supervision. The goal of this study is hence to investigate what factors affect Ph.D. students' satisfaction about the professional and personal relationships with their supervisors.Design/methodology/approachWe focus on the characteristics of the interactions between the student and the supervisor, controlling for other important factors, namely, the supervisor's and student's traits, and the character…
Focusing Knowledge-based Graph Argument Mining via Topic Modeling
2021
Decision-making usually takes five steps: identifying the problem, collecting data, extracting evidence, identifying pro and con arguments, and making decisions. Focusing on extracting evidence, this paper presents a hybrid model that combines latent Dirichlet allocation and word embeddings to obtain external knowledge from structured and unstructured data. We study the task of sentence-level argument mining, as arguments mostly require some degree of world knowledge to be identified and understood. Given a topic and a sentence, the goal is to classify whether a sentence represents an argument in regard to the topic. We use a topic model to extract topic- and sentence-specific evidence from…
ASINSTEN, Juan Carlos. Producción de Contenidos para Educación Virtual, Guía de Trabajo del Docente Contenidista, 2007, 179 páginas
2021
En estos tiempos convulsos, a traicion, con la urgencia y la impotencia como atributos de esta pandemia, hemos presenciado atonitos como se cierran las “puertas presenciales” de la ensenanza y se abren millones de “ventanas virtuales”. Pero mucho antes de llegar a esta situacion, observamos que la figura del profesor se modifica, la sociedad evoluciona y la manera de posicionarnos frente a la educacion ha cambiado. La ensenanza virtual es ya una oportunidad que no podemos ignorar y que tenemos que implementar sin lugar a dudas, asumiendo los riesgos que supone afrontar el uso de las TIC en el proceso de ensenanza y aprendizaje.
Spondylodiszitis durch eine Infektion mit Mycobacterium chimaera
2021
Cubic metamaterial crystal supporting broadband isotropic chiral phonons
2021
Chiral metamaterials can support chiral phonons leading to acoustical activity, the acoustical counterpart of optical activity. However, the properties of early metamaterial designs have been very highly anisotropic, and chiral acoustical phonons occurred only for selected high-symmetry directions. The authors propose a novel chiral metamaterial based on ``twisting'' a truncated octahedron in a simple-cubic unit cell. Not supported by crystal symmetry alone but rather by a tuned degeneracy, chiral phonons and large broadband acoustical activity are obtained for all phonon propagation directions in 3D. This result is notable because even isotropic achiral acoustical phonons are rare for crys…
false
2021
Background and objectives Choir singing has been associated with better mood and quality of life (QOL) in healthy older adults, but little is known about its potential cognitive benefits in aging. In this study, our aim was to compare the subjective (self-reported) and objective (test-based) cognitive functioning of senior choir singers and matched control subjects, coupled with assessment of mood, QOL, and social functioning. Research design and methods We performed a cross-sectional questionnaire study in 162 healthy older (age ≥ 60 years) adults (106 choir singers, 56 controls), including measures of cognition, mood, social engagement, QOL, and role of music in daily life. The choir sin…
Attitudes of Undergraduate Nursing Students towards Patient Safety: A Quasi-Experimental Study
2021
Improving nursing students’ attitudes towards patient safety is a current and relevant topic. This study aims to evaluate the effectiveness of an educational intervention based on critical incident and root cause analysis (RCA) techniques regarding attitudes towards patient safety in nursing students. A quasi-experimental before and after study was developed between January 2018 and December 2019 in a sample of 100 nursing students at Universitat Jaume I (Spain). The intervention was developed in two phases. Phase I was at university, where students applied the RCA technique in a real case. Phase II took place during clinical practice. Students used critical incidents to identify a risk sit…
Identification of clinical phenotypes and related survival in patients with large hccs
2021
Background. Hepatocellular carcinoma (HCC) factors, especially maximum tumor diameter (MTD), tumor multifocality, portal vein thrombosis (PVT), and serum alpha-fetoprotein (AFP), influence survival. Aim. To examine patterns of tumor factors in large HCC patients. Methods. A database of large HCC patients was examined. Results. A multiple Cox proportional hazard model on death identified low serum albumin levels and the presence of PVT and multifocality, with each having a hazard ratio ≥2.0. All combinations of these three parameters were examined in relation to survival. Using univariate Cox analysis, the combination of albumin >
Proton-neutron pairing correlations in the self-conjugate nucleus 42Sc
2021
Collinear laser spectroscopy of the N=Z=21 self-conjugate nucleus 42Sc has been performed at the JYFL IGISOL IV facility in order to determine the change in nuclear mean-square charge radius between the Iπ=0+ ground state and the Iπ=7+ isomer via the measurement of the 42g,42mSc isomer shift. New multi-configurational Dirac-Fock calculations for the atomic mass shift and field shift factors have enabled a recalibration of the charge radii of the 42−46Sc isotopes which were measured previously. While consistent with the treatment of proton-neutron, proton-proton and neutron-neutron pairing on an equal footing, the reduction in size for the isomer is observed to be of a significantly larger m…
VITOM® 3D in Arterio-Venous Fistulas: Single Centre Preliminary Surgical Experience
2021
Background: Arteriovenous fistula (AVF) is the vascular access of choice for hemodialysis patients. A correct microsurgical vascular anastomoses is essential to the optimal care of patients. Loupes can help surgeons perform such procedures, but often cause neck or back pain and fatigue. Aim: This study aimed to evaluate whether a video telescopic operating microscope (VITOM®; Karl Storz Endoscopy GmbH, Tuttlingen, Germany) could be used as a substitute for loupes to create microsurgical vascular anastomoses. Methods: We evaluated microsurgical anastomoses with VITOM® in 10 patients (6 male, 4 female) from January 2019 to December 2019. The created anastomoses were 7 side-to-side, 2 side-to-…
Bcl-xL as a Modulator of Senescence and Aging
2021
Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…
Acceptability of dual HIV/syphilis rapid test in community- and home-based testing strategy among transgender women in Buenos Aires, Argentina.
2021
Background: Little is known of acceptability and feasibility of dual HIV and syphilis rapid tests in community- and home-based provider-initiated strategies among transgender women (TGW), in Latin America. Objectives were (1) to assess the acceptability of this strategy and, (2) to determine the percentage of positive results of HIV and syphilis, analyze the correlates of HIV or syphilis positive results, and measure the rates of effective referral and treatment completion among TGW. Methods: A multidisciplinary team tested 89 TGW in Buenos Aires. An acceptability survey was administered after the HIV/syphilis Duo test was used. All confirmed cases were referred for treatment initiation. R…
La enseñanza digital en serio y el derecho a la educación en tiempos del coronavirus
2021
Especialmente desde una perspectiva jurídica, el estudio analiza las medidas en el ámbito educativo adoptadas en a nivel mundial y en España en razón del coronavirus: la “suspensión sin suspensión” de la educación especialmente a través de la enseñanza digital. Sin embargo, la educación digital se ha considerado “inferior”, “excepcional” y sólo “complementaria” de la presencial y fuente de graves barreras y peligros para la educación. Así ha sido en el ámbito internacional y también para el TEDH, el TC y nuestra legislación. Se tiene en cuenta el especial peligro de la desigualdad en la educación digital y, ya en el caso de la pandemia, se describen algunas medidas especiales de equidad e i…
VIDAL PRADO, Carlos. El derecho a la educación en España. Bases constitucionales para el acuerdo y cuestiones controvertidas, colección Debates Const…
2021
El derecho a la educacion en Espana. Bases constitucionales para el acuerdo y cuestiones controvertidas representa un exhaustivo y riguroso estudio del derecho a la educacion en Espana . La obra de Vidal Prado hace un estudio pormenorizado del derecho a la educacion desde diversas perspectivas, pero siempre desde una linea argumental claramente definida por un prolijo estudio normativo y jurisprudencial. De hecho, la profunda investigacion normativa se ve reforzada por el estudio de la continua labor del Tribunal Constitucional en la materia del derecho a la educacion, por lo que el analisis jurisprudencial es determinante para entender con amplitud la materia abordada.
An Integrated Approach for the Valorization of Cheese Whey
2021
Taking into account the large amount of whey that is produced during the cheese production process and the constant demand by society for more sustainable processes, in accordance with Sustainable Development Goals (SDGs) and the circular economy concept, it is necessary to adapt two-unit operations into a single process, allowing us to not only valorize a part of the whey but the whole process, which is known as bioprocess integration. In this sense, the adaptation of different processes, for example, physicochemical (micro, ultra and nanofiltration) and fermentation, that are commonly used to obtain proteins, lactose and other compounds with different activities (antioxidant, antifungal, …
Intrahematomal Ultrasound Enhances RtPA-Fibrinolysis in a Porcine Model of Intracerebral Hemorrhage
2021
Catheter-based ultrasound-thrombolysis has been successfully used in a small clinical trial in order to enhance recombinant tissue plasminogen activator (rtPA)-fibrinolysis, for the treatment of spontaneous intracerebral hemorrhages (ICHs). The aim of this study was to investigate the ultra-early effects of ultrasound on hematoma and the surrounding brain tissue in a porcine ICH-model. To achieve this, 21 pigs with a right frontal ICH were randomly assigned to four groups: (1) drainage (n = 3), (2) drainage + rtPA (n = 6), (3) drainage + ultrasound (n = 6), and (4) drainage + ultrasound + rtPA (n = 6). The hematoma volume assessment was performed using cranial MRI before and after the treat…
Stimulation of sewage sludge treatment by carbon sources and bioaugmentation with a sludge-derived microbial consortium
2021
Abstract Recently, sewage sludge (SS) disposal has become one of the greatest global challenges. In this study, we aimed to evaluate the effect of faba bean straw (Straw-B), wheat straw (Straw-W), and wood-chip pellets (WCP) amended to SS, as well as bioaugmentation (BA), on the physicochemical characteristics and structure of the microbial community of the treated SS. Sixteen days of incubation of SS-containing mixtures revealed the highest efficiency of Straw-W(BA) in terms of SS stabilisation, i.e., the highest and most stable respiration intensity, the lowest ammonia emission, and the highest stimulation effect on the cress seedling growth. Shotgun sequencing data analysis showed that P…
crystal structure of glutathione transferase omega 2c from trametes versicolor in complex with naringenin
2021
triazine cathepsin inhibitor complex
2021
crystal structure of glutathione transferase omega 2c from trametes versicolor
2021
Applications of Social Network Analysis in healthcare: midwives and pregnant women
2021
Doctoral Thesis ReviewCamacho, F. (2020): "Aplicaciones del Analisis de Redes Sociales en el ambito sanitario: matronas y gestantes".
Temperature dependence of desolvation effects in hydrogen-bonded spin crossover complexes
2021
The synthesis, crystal structure and (photo)magnetic properties of the anhydrous spin crossover salt of formula [Fe(bpp)2](C6H8O4) (1) (bpp = 2,6-bis(pyrazol-3-yl)pyridine; C6H8O4 = adipate dianion), obtained by desolvation at 400 K of the original tetrahydrate in a single-crystal-to-single-crystal (SC–SC) transformation, are reported. This work offers a comparison between this compound and the previously reported hydrated material ([Fe(bpp)2](C6H8O4)·4H2O, 1·4H2O), highlighting the significance of the thermal conditions used in the dehydration-rehydration processes. In both compounds, a hydrogen-bonded network between iron(II) complexes and adipate anions is observed. The original tetrahyd…
crystal structure of glutathione transferase omega 2c from trametes versicolor in complex with oxyresveratrol
2021
ICPM NEWS: The European Training Network ETUDE (Encompassing Training in Functional Disorders across Europe) Is Recruiting 15 Early-Stage Researchers
2021
Commentary: Anderson‐Fabry Disease: A Rare Cause of Levodopa‐Responsive Early Onset Parkinsonism
2021
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