showing 36 of ~574560 from 574555 documents
Neuroprotective and Mitoprotective Effects of Lemon IntegroPectin on SH-SY5Y Cells
2021
AbstractLemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, including mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These result…
TIVOLI, HADRIAN'S VILLA: THE PLUTONIUM PROJECT (COMUNE DI TIVOLI, PROVINCIA DI ROMA, REGIONE LAZIO)
2021
The Universities of Pavia and Oxford continued their investigations in Villa Adriana, in the area called Plutonium, traditionally interpreted as a reproduction of the Underworld, and located on one of the highest rises of the complex, in the east part of the Villa. The excavations took place from 1 to 21 July 2019. A team of 12 graduate students and postdoctoral researchers took part in the project, both from Oxford and Pavia Universities (S. Andronio, I. Bossolino, E. Casarotti, A. Dalgkitsi, E. Di Virgilio, V. Jukic Buca, A. Poldi Allai, G. Restaino, T. Runeckles, A. Verde). Dr Gilberto Montali, from the University of Palermo, supervised the architectural survey and documentation of the a…
Behavioural responses of breeding arctic sandpipers to ground-surface temperature and primary productivity
2021
Most birds incubate their eggs, which requires time and energy at the expense of other activities. Birds generally have two incubation strategies: biparental where both mates cooperate in incubating eggs, and uniparental where a single parent incubates. In harsh and unpredictable environments, incubation is challenging due to high energetic demands and variable resource availability. We studied the relationships between the incubation behaviour of sandpipers (genus Calidris) and two environmental variables: temperature and a proxy of primary productivity (i.e. NDVI). We investigated how these relationships vary between incubation strategies and across species among strategies. We also stud…
De Garengeot Hernia: Case Report and Review of the Literature of a Rare Femoral Hernia
2021
AbstractDe Garengeot hernia is a rare femoral hernia defined as the presence of the appendix within the femoral hernia sac. The incidence of appendicitis in this type of hernia is a rare condition that accounts for 0.08–0.13% of all De Garengeot hernias. We describe the case of a 61-year-old woman that presented at the emergency department with a tender mass (diameter 10 × 8 cm) in the right groin region for 5 days associated with pain in lower right abdomen and accompanied by fever (38 °C). Computed tomography (CT) of the abdomen revealed the presence of a complex fluid collection with small foci of air in the right inguinal region, measuring 9 × 7 × 10 cm in the 3 orthogonal dimensions an…
The potential of antimicrobial peptides isolated from freshwater crayfish species in new drug development: A review
2021
Abstract The much-publicised increased resistance of pathogenic bacteria to conventional antibiotics has focused research effort on the characterization of new antimicrobial drugs. In this context, antimicrobial peptides (AMPs) extracted from animals are considered a promising alternative to conventional antibiotics. In recent years, freshwater crayfish species have emerged as an important source of bioactive compounds. In fact, these invertebrates rely on an innate immune system based on cellular responses and on the production of important effectors in the haemolymph, such as AMPs, which are produced and stored in granules in haemocytes and released after stimulation. These effectors are …
Assessing coastal habitats with Juniperus sp. pl. in the Iberian Peninsula and on the Balearic Islands
2021
Coastal habitats with Juniperus sp. pl. represent the mature stage in the ecological succession of dune ecosystems. Maritime junipers (Juniperus macrocarpa), prickly junipers (J. navicularis) and c...
Causas de la lesión de isquiosurales en fútbol: Una revisión bibliográfica desde las etapas formativas hasta la profesional
2021
espanolObjetivos: identificar las principales causas de lesion de isquiosurales en las diferentes etapas de formacion, desde la etapa sub-12 hasta la etapaprofesional, y establecer la influencia de la lesion previa de isquiosurales como causa principal de sufrir una nueva lesion.Metodo: la busqueda bibliografica se realizo en Dialnet, Pubmed, Web of Science, Scopus y SportDISCUS, entre las fechas de enero de 2010 hasta mayo de2020.Resultados: la busqueda concluyo que el patron de lesion isquiosural mas concurrido es el de jugador de edad avanzada, con mayores valores de fuerza ymenores valores de flexibilidad, y con un mayor grado de anteversion pelvica. El envejecimiento, los movimientos c…
Small molecule DNA-PK inhibitors as potential cancer therapy: a patent review (2010–present)
2021
Introduction: DNA-dependent protein kinase (DNA-PK) plays a crucial role in the repair of DSBs via non-homologous end joining (NHEJ). Several DNA-PK inhibitors are being investigated for potential anticancer treatment in clinical trials.Area covered: This review aims to give an overview of patents published since 2010 by analyzing the patent space and structure features of scaffolds used in those patents. It also discusses the recent clinical developments and provides perspectives on future challenges and directions in this field.Expert opinion: As a key component of the DNA damage response (DDR) pathway, DNA-PK appears to be a viable drug target for anticancer therapy. The clinical investi…
A Further Approach in Omnichannel LSQ, Satisfaction and Customer Loyalty
2021
PurposeThe purpose of this research is to analyse the LSQ in the context of three different omni-channel purchasing scenarios while considering four dimensions (timeliness, availability, condition and return of the product) and to assess their impact on customer satisfaction and loyalty. In addition, an evaluation of the relationship between satisfaction and loyalty in the mentioned omni-channel scenarios is investigated.Design/methodology/approachA mixed two-phase research methodology is proposed: an initial qualitative analysis with six focus groups followed by quantitative research through surveys with a sample of 323 individuals. The proposed scales were tested for three purchase scenar…
Hidup Berdampingan Dengan Hidupan Liar di Masa Pandemi Covid-19 (Interaksi dengan Pemirsa Pro2 FM RRI Manokwari)
2021
ABSTRACT 
 Culturally, the relationship between the people and wild animals in Papua is close-knitted and inseparable. In response to this, through the Manokwari Menyapa program of RRI Manokwari, we share information about the current relationship between people and wildlife during the Covid-19 pandemic. This community service activity is carried out through radio broadcasts, which is an interactive program between listeners and informants on Monday, July 20, 2020. Listeners’ responses vary widely including the impact of consuming animal meat, keeping animals as pet animals, and the consequences of forest loss to the intense exposure of animals to the people. Another thing that was rev…
Constraints on electromagnetic form factors of sub-GeV dark matter from the cosmic microwave background anisotropy
2021
We consider dark matter which have non-zero electromagnetic form factors like electric/magnetic dipole moments and anapole moment for fermionic dark matter and Rayleigh form factor for scalar dark matter. We consider dark matter mass $m_\chi > \cal{ O}({\rm MeV})$ and put constraints on their mass and electromagnetic couplings from CMB and LSS observations. Fermionic dark matter with non-zero electromagnetic form factors can annihilate to $e^+ e^-$ and scalar dark matter can annihilate to $2\gamma$ at the time of recombination and distort the CMB. We analyze dark matter with multipole moments with Planck and BAO observations. We find upper bounds on anapole moment $g_{A}<7.163\times 10^{3} …
Social integration of Ethiopian and Eritrean women in Switzerland through informal sport settings
2021
This study investigated the role of informal sport settings (i.e. self-organised and non-voluntary sports clubs) in the social integration of Ethiopian and Eritrean women into Swiss society. Social integration seen as a multidimensional, interdependent process between the interaction of social bond, bridge and links; and two-way interaction between the migrant and local community. Thematic analysis of semi-structured interviews and focus group discussions (n���=���12, 18���51���years old) was used to understand the interplay between social integration and participation in informal sport settings. The findings indicated that such settings have become a crucial sphere for establishing and reb…
Gender differences on the WAIS-IV in patients with schizophrenia
2021
Introduccion Los resultados de los estudios que han investigado diferencias de genero en funcionamiento neuropsicologico en la esquizofrenia han sido inconsistentes. Diferencias en la fase de la enfermedad, en las caracteristicas demograficas y clinicas de las muestras y en los instrumentos utilizados podrian explicar esa heterogeneidad. Objetivo Investigar la heterogeneidad en los resultados comparando el funcionamiento cognitivo de pacientes con diagnostico de esquizofrenia. Metodo Veinticinco mujeres y veinticinco hombres pacientes con diagnostico de esquizofrenia equiparados en edad, edad al inicio de la enfermedad y nivel educativo se evaluaron en funcionamiento cognitivo utilizando la…
Efficacy and predictability of maxillary and mandibular expansion with the Invisalign® system
2021
Background The purpose of this study is to evaluate the efficacy and predictability of upper and lower orthodontic expansion with the Invisalign® system. Material and Methods From a sample of 167 patients; 64 upper and 51 lower arches were randomly selected from patients who had been treated with plastic orthodontics (Invisalign® aligners, SmartTrack® material). Digital models were extracted at the beginning (ModT1) and at the end of treatment (ModT2) as well as the final ClinCheck® (CkT2). The canine, premolar and molar width was measured at the gingival and cuspid level of both arches, as well as the inclination of the upper first molar. Likewise, both arches were divided regarding the pl…
Rational normal curves and Hadamard products
2021
AbstractGiven $$r>n$$ r > n general hyperplanes in $$\mathbb P^n,$$ P n , a star configuration of points is the set of all the n-wise intersection of the hyperplanes. We introduce contact star configurations, which are star configurations where all the hyperplanes are osculating to the same rational normal curve. In this paper, we find a relation between this construction and Hadamard products of linear varieties. Moreover, we study the union of contact star configurations on a same conic in $$\mathbb P^2$$ P 2 , we prove that the union of two contact star configurations has a special h-vector and, in some cases, this is a complete intersection.
The Effectiveness of EMOVERE: An Emotional Education Program for Young Couples
2021
Our aim was to assess the effectiveness of EMOVERE, a psychoeducational and experiential program to increase emotion regulation in couples. Forty-four young couples (n = 88) aged between 18 and 36 years old participated in the study (53.4% women
Socio-demographic characteristics associated with emotional and social loneliness among older adults.
2021
Abstract Background International studies provide an overview of socio-demographic characteristics associated with loneliness among older adults, but few studies distinguished between emotional and social loneliness. This study examined socio-demographic characteristics associated with emotional and social loneliness. Methods Data of 2251 community-dwelling older adults, included at the baseline measure of the Urban Health Centers Europe (UHCE) project, were analysed. Loneliness was measured with the 6-item De Jong-Gierveld Loneliness Scale. Multivariable logistic regression models were used to evaluate associations between age, sex, living situation, educational level, migration background…
Enhancing nonclassical bosonic correlations in a Quantum Walk network through experimental control of disorder
2021
The presence of disorder and inhomogeneities in quantum networks has often been unexpectedly beneficial for both quantum and classical resources. Here, we experimentally realize a controllable inhomogenous Quantum Walk dynamics, which can be exploited to investigate the effect of coherent disorder on the quantum correlations between two indistinguishable photons. Through the imposition of suitable disorder configurations, we observe two photon states which exhibit an enhancement in the quantum correlations between two modes of the network, compared to the case of an ordered Quantum Walk. Different configurations of disorder can steer the system towards different realizations of such an enha…
Creative industries and productivity in the European regions. Is there a Mediterranean effect?
2021
Chi2 profiles from Valencia neutrino global fit
2021
We provide here the 1D and 2D chi2 profiles from our most recent global fit of neutrino oscillation data (DOI:10.1007/JHEP02(2021)071). The files are available at https://globalfit.astroparticles.es/.
Intérêt d’outils digitaux dans le maintien d’un parcours de soins obésité dans le contexte épidémique Covid-19. Retour de l’expérimentation article 5…
2021
L’épidémie de Covid-19, au-delà de mettre en évidence l’obésité comme facteur pronostique important, modifie grandement la prise en charge de cette maladie chronique. L’expérimentation article 51 Espace médical nutrition et obésité (EMNO) a dû intégrer des outils numériques pour maintenir les parcours de soins. Cette démarche a également été enrichie par l’apport d’un outil d’éducation thérapeutique digital. L’ensemble du processus de prise en charge a ainsi été réalisé malgré la situation, avec un retour très positif des patients inclus dans l’expérimentation. En contexte épidémique, le maintien des parcours de soins d’une maladie chronique comme l’obésité peut ainsi être assuré avec l’app…
Jāzeps Rancāns un uzsaukums vēlēšanām Eslingenē
2021
Raksts satur informāciju par Latvijas Universitātes Muzeja LU vēstures kolekcijas krājumā esošo Latvijas Centrālās padomes locekļa Jāzepa Rancāna vēlēšanu uzsaukumu Eslingenes latviešiem, kuri nonāca trimdā sakarā ar otrreizējo PSRS okupāciju pēc Otrā pasaules kara. Blakus Eslingenes vēlēšanu uzsaukuma analīzei tiek analizēt arī paša J. Rancāna personības loma Latvijas valsts un LU vēsturē, sasaistot ar Romas katoļu baznīcas lomu Latvijas politiskajā un sabiedriskajā dzīvē.
The Role of Low Complexity Regions in Protein Interaction Modes: An Illustration in Huntingtin
2021
Low complexity regions (LCRs) are very frequent in protein sequences, generally having a lower propensity to form structured domains and tending to be much less evolutionarily conserved than globular domains. Their higher abundance in eukaryotes and in species with more cellular types agrees with a growing number of reports on their function in protein interactions regulated by post-translational modifications. LCRs facilitate the increase of regulatory and network complexity required with the emergence of organisms with more complex tissue distribution and development. Although the low conservation and structural flexibility of LCRs complicate their study, evolutionary studies of proteins …
A case of late diagnosis and management of 46 XY complete gonadal dysgenesis in adulthood
2021
Associations of temperament types and gender of early adolescents and teachers with adolescents’ school well‐being
2021
This study examined the role of temperament type and gender of adolescents and teachers in adolescents’ well‐being in school. The sample consisted of 677 Finnish students and 56 classroom teachers. Parents rated adolescent temperament and teachers rated their own temperament in autumn of Grade 6. Self‐reports of school well‐being among adolescents were obtained in autumn and the fall of Grade 6. The results showed that being a girl and having resilient temperament type predicted higher school well‐being. In turn, boys with undercontrolled temperament, who were otherwise at risk for decreased school well‐being, particularly benefited from having a female teacher with resilient temperament. O…
Time multiplexing super-resolved imaging without a priori knowledge of the spatial distribution of the encoding structured illumination
2021
Time multiplexing is a super-resolution technique that sacrifices time to overcome the resolution reduction obtained because of diffraction. There are many super resolution methods based on time multiplexing, but all of them require a priori knowledge of the time changing encoding mask, which is projected on the object and used to encode and decode the high-resolution information. In this paper, we present a time multiplexing technique that does not require the a priori knowledge on the projected encoding mask. First, the theoretical concept of the technique is demonstrated; then, numerical simulations and experimental results are presented.
Infrared facets of the three-gluon vertex
2021
We present novel lattice results for the form factors of the quenched three-gluon vertex of QCD, in two special kinematic configurations that depend on a single momentum scale. We consider three form factors, two associated with a classical tensor structure and one without tree-level counterpart, exhibiting markedly different infrared behaviors. Specifically, while the former display the typical suppression driven by a negative logarithmic singularity at the origin, the latter saturates at a small negative constant. These exceptional features are analyzed within the Schwinger-Dyson framework, with the aid of special relations obtained from the Slavnov-Taylor identities of the theory. The em…
Validation and implementation of a commercial real-time PCR assay for direct detection of Candida auris from surveillance samples.
2021
Background Rapid and reliable laboratory methods are required for detecting the nosocomial yeast Candida auris. AurisID® (Olm Diagnostics, England) is a real-time PCR assay approved for detecting C. auris in fungal cultures as well as directly from blood samples, involving a nucleic acid extraction as a prior step. Objectives The purpose of this study is to validate the AurisID® kit for direct detection of C. auris from surveillance samples without prior DNA extraction and to analyze the results of implementing this methodology to our daily laboratory routine protocol for C. auris surveillance studies. Methods Our PCR method using the AurisID® kit was compared with our routine protocol, con…
2020 global reassessment of the neutrino oscillation picture
2021
We present an updated global fit of neutrino oscillation data in the simplest three-neutrino framework. In the present study we include up-to-date analyses from a number of experiments. Concerning the atmospheric and solar sectors, we give updated analyses of DeepCore and SNO data, respectively. We have also included the latest electron antineutrino data collected by the Daya Bay and RENO reactor experiments, and the long-baseline T2K and NO$\nu$A measurements. These new analyses result in more accurate measurements of $\theta_{13}$, $\theta_{12}$, $\Delta m_{21}^2$ and $|\Delta m_{31}^2|$. The best fit value for the atmospheric angle $\theta_{23}$ lies in the second octant, but first octan…
Revisiting the Epipalaeolithic-Neolithic Transition in the Extreme NW of Africa : The Latest Results of the Chronological Sequence of the Cave of Kaf…
2021
[EN] This study focuses on the chronostratigraphic sequence of the Cave of Kaf Taht el-Ghar (Dar Ben Karrich, Tétouan, Morocco) excavated in 2012 in the framework of the AGRIWESTMED research project. The broad sequence reveals a series of occupations ranging from the Pleistocene (Moroccan Aterian) to recent historical times. Our research identifies a rich Early Neolithic phase (sixth millennium cal BC) containing the earliest pottery and domesticated animal and plant remains in the western Maghreb. However, this Early Neolithic level is not an immediate successor of the last traces of the Epipalaeolithic hunter-gatherer occupation, which started at the end of the Younger Dryas (10,900–9700 …
Nueve tesis introductorias sobre la distopía
2021
Nine introductory theses about dystopia
 
 Resumen: Este artículo proporciona una introducción actualizada a la distopía y una exégesis del apogeo ilimitado que esta vive. Y lo hace planteando nueve tesis. El supuesto de partida es que el término “distopía” no designa solamente una forma literaria. Sus premisas, metodologías y actitudes elementales son visibles en el pensamiento social contemporáneo y otras muchas expresiones culturales. En las dos primeras tesis diferencio el género distópico de otros géneros afines y sondeo las coincidencias temáticas que atesoran sus expresiones literarias y filosóficas. A lo largo de las tres tesis posteriores, señalo las causas sociales e ide…
Disparities in Accessing Sexual and Reproductive Health Services at the Intersection of Disability and Female Adolescence in Tanzania
2021
Despite at times having greater needs for sexual and reproductive health (SRH) services, adolescents with disabilities often face challenges when trying to access them. This inaccessibility is further exacerbated during female adolescence. The qualitative study examines how SRH services respond to the characteristics of Tanzanian adolescent females with disabilities. We used the method of empathy-based stories to investigate the perceptions of 136 adolescent females with disabilities of their access to SRH services in Tanzania. The study used thematic content analysis and the Levesque model of health care access was applied as an analytical framework. The results demonstrate that discrimina…
‘Then we were ready to be radicals!’ : school student activism in Finnish upper secondary schools in 1960–1967
2021
In the Western countries, Scandinavia and Finland included, the legacy of the student movement of the 1960s has been extensive and established a fixed narrative of a radical movement. This article challenges the elitists and university-centred grand narrative and argues that the student movement was more multifaceted and mobilized young people of various ages and backgrounds. This is done by addressing the international student movement from the perspective of school-aged students in Finnish upper secondary schools, focusing on student activism carried out in school-sanctioned student associations. Above all, this article aims to distinguish the relatively unknown history of the Scandinavia…
Politics, planning, and ruling: the art of taming public participation
2021
Public participation is still a democratic challenge to city and municipal governments. Numerous studies have suggested experiments on participative processes, and conflictual consensus is seen as ...
Utopías y ucronías. Una aproximación histórico-conceptural, editat per Juan de Dios Bares i Faustino Oncina
2021
RESSENYA / RESENA /REVIEW Utopias y ucronias. Una aproximacion historico-conceptural , editat per Juan de Dios Bares i Faustino Oncina
High Optical Performance of Cyan‐Emissive CsPbBr3 Perovskite Quantum Dots Embedded in Molecular Organogels
2021
This is the pre-peer reviewed version of the following article: High Optical Performance of Cyan‐Emissive CsPbBr3 Perovskite Quantum Dots Embedded in Molecular Organogels, which has been published in final form at https://doi.org/10.1002/adom.202001786. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions." Perovskite quantum dots (PQDs) have fascinating optoelectronic properties, such as high photoluminescence quantum yield (PLQY) for a broad range of materials, and the possibility to obtain different bandgaps with the same material or halide combinations. Nevertheless, blue‐emissive materials generally present…