showing 36 of ~574560 from 574555 documents

Development and Preliminary Validation of Social Media as an Educational and Professional Tool Student Perceptions Scale (SMEPT-SPS)

2021

Although social media has an increasing presence both in university and sports settings, in the sports-management education context, no instruments (without being focused on one particular social-media platform, e.g., Facebook and Twitter) have been developed and validated that globally allow the academy to explore the perceptions of sports-management students concerning the educational and professional learning potential that these tools offer. Therefore, this research’s main objective is to develop and perform a preliminary validation of the social media as an educational and professional tool student perceptions scale (SMEPT-SPS). This study sample was composed of 90 Spanish undergraduat…

confirmatory factor analysisHigher educationsocial mediaGeography Planning and DevelopmentValidityTJ807-830Sample (statistics)Context (language use)Management Monitoring Policy and Lawpsychometric propertiesTD194-195Renewable energy sourcesProfessional learning community0502 economics and businesssports-management educationComputingMilieux_COMPUTERSANDEDUCATIONSocial mediaGE1-350EsportsMedical educationEnvironmental effects of industries and plantsRenewable Energy Sustainability and the Environmentbusiness.industry05 social sciencesscale developmentpreliminary validation050301 educationConfirmatory factor analysisEnvironmental sciencesScale (social sciences)higher educationEducació físicaX990Psychologybusiness0503 education050212 sport leisure & tourisminstrumental studiesSustainability

Quelques paradoxes du corpus saussurien : le « psychologisme » de Saussure à l’« âge psychologique » des sciences humaines

2021

Conférence en ligne (Zoom); International audience; No abstract

[SHS.LITT] Humanities and Social Sciences/Literature[SHS.LITT]Humanities and Social Sciences/LiteratureInformationSystems_INFORMATIONINTERFACESANDPRESENTATION(e.g.HCI)ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION[SHS.LANGUE]Humanities and Social Sciences/LinguisticsPsychologisme[SHS.LANGUE] Humanities and Social Sciences/LinguisticsComputingMilieux_MISCELLANEOUSPhilosophie du langageComputingMethodologies_COMPUTERGRAPHICS

Why Am I the Only One You’re Talking to, Talk to Them, They Haven’t Said a Word? : Pitfalls and Challenges of Having the Child in the Focus of Family…

2021

Children with conduct disorders are at risk of being positioned in the family therapy as ‘the problem’. This study describes how the difficulties were talked about and how the child coped in this situation. The results showed: the parents produced symptom-oriented problem talk about the child’s behavior, rendering systemic reformulation of the problem challenging. The negative interaction made the climate unsafe and impaired consideration of the child’s behavior as a meaningful way for the child to become seen and heard. This study enriches understanding of the therapeutic challenge therapists face with high-risk families from the very beginning of the treatment. peerReviewed

Family therapyFocus (computing)PsychotherapistvuorovaikutusSocial Psychologyconduct disorder05 social sciencesinteractionlapset (ikäryhmät)perheterapiamedicine.diseaseHavenkäyttäytymishäiriötClinical Psychologyproblem-talk050902 family studiesConduct disordermental disordersmedicinefamily therapy0509 other social sciencesPsychologylapset (perheenjäsenet)Word (computer architecture)

The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance

2021

ABSTRACTFTSJ1 is a conserved human 2’-O-methyltransferase (Nm-MTase) that modifies several transfer RNAs (tRNAs) at position 32 and the wobble position 34 in the AntiCodon Loop (ACL). Its loss of function has been linked to Non-Syndromic X-Linked Intellectual Disability (NSXLID), and more recently to cancers. However, the molecular mechanisms underlying these pathologies are currently unclear. Here we report a novelFTSJ1pathogenic variant from a NSXLID patient. Using blood cells derived from this patient and other affected individuals carryingFTSJ1mutations, we performed an unbiased and comprehensive RiboMethSeq analysis to map the ribose methylation (Nm) on all human tRNAs and identify nov…

Transcriptomeeducation.field_of_studyNeuriteTransfer RNAmicroRNAPopulationMethylationBiologyeducationGeneLoss functionCell biology

Umbilical hernioplasty in cirrhotic patients with ascites A case control study

2021

Umbilical hernia is a very frequent pathology, and plastic with prosthetic material is the most frequently used surgical procedure currently used for its repair. In patients with cirrhosis in asciic phase, this pathology is particularly frequent, with a tendency to rapidly increase in size and to become symptomatic. In the past treatment with traditional surgery in cirrhotic patients was considered problematic and was viewed with reserve, and only recently is the surgical approach recommended also in these patients. This study is aimed to evaluate the feasibility and safety of open umbilical hernia plastic with prosthetic material in cirrhotic and ascitic patients.Our case-control study was…

Liver CirrhosisMaleCase-Control StudiesAscitesHumanshernioplastyHernia UmbilicalHerniorrhaphy

‘An Apple A Day’?: Psychiatrists, Psychologists and Psychotherapists Report Poor Literacy for Nutritional Medicine: International Survey …

2021

Abstract: Nutritional interventions have beneficial effects on certain psychiatric disorder symptomatology and common physical health comorbidities. However, studies evaluating nutritional literacy in mental health professionals (MHP) are scarce. This study aimed to assess the degree of self-rated training and literacy relating to nutrition in MHPs. We conducted a cross-sectional survey across 52-countries. Surveys were distributed via colleagues and professional societies. Data were collected regarding self-reported general nutrition knowledge, nutrition education, learning opportunities, and the tendency to recommend food supplements or specific diets in clinical practice. In total, 1056 …

psychiatry_mental_health_studiesallergology

Five decades of corporate entrepreneurship research: measuring and mapping the field

2021

AbstractResearch on corporate entrepreneurship—venturing activities by established corporations—has received increasing scholarly attention. We employ bibliometric methods to analyze the literature on corporate entrepreneurship published over the last five decades. Based on the results of citation and co-citation analyses, we reveal central works in the field and how they are interconnected. We investigate the underlying intellectual structure of the field. Our findings provide evidence of the growing maturity and interdisciplinarity of corporate entrepreneurship and provide insight into research themes. We find that resource-based view and its extensions still remain the predominant theore…

EntrepreneurshipBibliometric analysisManagement of Technology and InnovationField (Bourdieu)Regional scienceSociologyEconomiaIntellectual structureCitationMaturity (finance)Management Information SystemsInternational Entrepreneurship and Management Journal

The evaluation of workers by customers as a method of control and monitoring in firms: Digital reputation and the European Union's General Data Prote…

2021

As a method of surveillance and monitoring, the evaluation of workers by customers and employers and the disclosure of the results pose a series of challenges for the current legal framework of the European Union (EU). Employees subject to such evaluations are exposed to a far more intense and wider degree of monitoring of their work than traditional workers. The phenomenon arises from the adoption of a customer perspective, seeking to make work observable at all times, without any cost to firms. In this light, the author analyses the EU's General Data Protection Regulation, which establishes very specific restrictions when requesting and disclosing information about workers.

Organizational Behavior and Human Resource ManagementFreedom of informationStrategy and Managementmedia_common.quotation_subjectControl (management)Work (electrical)Management of Technology and InnovationGeneral Data Protection RegulationEmployee monitoringmedia_common.cataloged_instanceData Protection Act 1998BusinessEuropean unionMarketingmedia_commonReputationInternational Labour Review

Absolute targets for HCV elimination and national health policy paradigms: Foreseeing future requirements

2021

The World Health Organization (WHO) targets for eliminating HCV by 2030 may be overambitious for many high-income countries. Recent analyses (ie, data from 2017 to 2019) show that only 11 countries are on track for meeting WHO’s elimination targets. For a country to be truly on track, it is important that the majority of infected individuals be identified and treated. There is still a need for country and population-specific evaluations within the different HCV screening and treatment strategies available, in order to assess their cost-effectiveness and sustainability and support an evidence-based policy for HCV elimination. Any health policy model is affected by the diversity and quality o…

media_common.quotation_subjectWorld Health Organizationdisease burden03 medical and health sciences0302 clinical medicineOrder (exchange)PandemicHumansQuality (business)Disease EradicationSet (psychology)Disease burdenHealth policymedia_commonPublic economicsHepatologyHCV screeningHealth PolicymicroeliminationCOVID-19Hepatitis CWHO targetHCV elimination030220 oncology & carcinogenesisSustainability030211 gastroenterology & hepatologyBusinessHumanDiversity (politics)Liver International

Contenido preventivo en la negociación colectiva

2021

espanolEn este trabajo se realiza un analisis cualitativo y cuantitativo de los convenios colectivos de ambito estatal de los dos ultimos anos y medio en cuanto a la regulacion que contienen sobre la materia de seguridad y salud laboral. En este sentido, se procede a estudiar con detalle la regulacion convencional sobre la formacion, vigilancia de la salud, organos de representacion de los trabajadores, colectivos con proteccion especial y nuevos riesgos emergentes, en concreto, el acoso moral. Se concluye en general, que, desafortunadamente, y aunque se ha conseguido un avance importante al respecto, en los momentos actuales, y en general, la materia preventiva aun no ha tenido un adecuado…

Health surveillancePolitical scienceProductive sectorHumanities

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…

2021

Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…

virusesCultured tumor cellsSynthesis PhaseCell Cycle ProteinsBiochemistryCell Cycle and Cell DivisionBiology (General)PhosphorylationPost-Translational ModificationCyclin0303 health sciencesbiologyKinaseChemistry030302 biochemistry & molecular biologyRetinoblastoma proteinvirus diseasesCell DifferentiationTransfectionCyclin-Dependent KinasesCell biologyEnterovirus B HumanCell ProcessesPhosphorylationCell linesBiological culturesResearch ArticleQH301-705.5Protein subunitImmunologyCoxsackievirus InfectionsTransfectionResearch and Analysis MethodsMicrobiology03 medical and health sciencesVirologyCyclinsGeneticsHumansHeLa cellsMolecular Biology TechniquesMolecular Biology030304 developmental biologyCell ProliferationCell growthG1 PhaseBiology and Life SciencesProteinsCell Cycle CheckpointsCell BiologyRC581-607Cell culturesPancreatitisbiology.proteinParasitologyCapsid ProteinsImmunologic diseases. AllergyCyclin-dependent kinase 7Cyclin-Dependent Kinase-Activating KinaseTranscription FactorsPLoS pathogens

Phosphine Oxide Derivative as a Passivating Agent to Enhance the Performance of Perovskite Solar Cells

2021

Defects of metal-halide perovskites detrimentally influence the optoelectronic properties of the thin film and, ultimately, the photovoltaic performance of perovskite solar cells (PSCs). Especially, defect-mediated nonradiative recombination that occurs at the perovskite interface significantly limits the power conversion efficiency (PCE) of PSCs. In this regard, interfacial engineering or surface treatment of perovskites has become a viable strategy for reducing the density of surface defects, thereby improving the PCE of PSCs. Here, an organic molecule, tris(5-((tetrahydro-2H-pyran-2-yl)oxy)pentyl) phosphine oxide (THPPO), is synthesized and introduced as a defect passivation agent in PSC…

Phosphine oxideMaterials sciencePhotovoltaic systemEnergy Engineering and Power Technology02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology7. Clean energy01 natural sciences0104 chemical scienceschemistry.chemical_compoundchemistryChemical engineeringMaterials ChemistryElectrochemistryChemical Engineering (miscellaneous)Lewis acids and basesElectrical and Electronic EngineeringThin film0210 nano-technologyÒxidsMaterialsDerivative (chemistry)Cèl·lules fotoelèctriquesPerovskite (structure)ACS Applied Energy Materials

Size‐Based Cationic Molecular Sieving through Solid‐State Nanochannels

2021

Advanced materials interfaces 8(6), 2001766 (2021). doi:10.1002/admi.202001766

Materials scienceChemical engineeringMechanics of MaterialsMechanical EngineeringSolid-stateCationic polymerizationIonic conductivity600ddc:600

false

2021

Functional proprioceptive information is required to allow an individual to interact with the environment effectively for everyday activities such as locomotion and object manipulation. Specifically, research suggests that application of compression garments could improve proprioceptive regulation of action by enhancing sensorimotor system noise in individuals of different ages and capacities. However, limited research has been conducted with samples of elderly people thus far. This study aimed to examine acute effects of wearing knee-length socks (KLS) of various compression levels on ankle joint position sense in community-dwelling, older adults. A total of 26 participants (12 male and 14…

Acute effectsmedicine.medical_specialtyMultidisciplinaryProprioceptioncomputer.internet_protocolbusiness.industryJoint position sense030229 sport sciencesCompression (physics)Barefoot03 medical and health sciences0302 clinical medicineSOCKSPhysical medicine and rehabilitationmedicine.anatomical_structureMedicineAnklebusinesscomputer030217 neurology & neurosurgeryBalance (ability)PLOS ONE

Real-time Multispectral Image Processing and Registration on 3D Point Cloud for Vineyard Analysis

2021

International audience; Nowadays, precision agriculture and precision viticulture are under strong development. In order to accomplish effective actions, robots require robust perception of the culture and the surrounding environment. Computer vision systems have to identify plant parts (branches, stems, leaves, flowers, fruits, vegetables, etc.) and their respective health status. Moreover, they must merge various plant information, to measure agronomic indices, to classify them and finally to extract data to enable the agriculturist or expert to make a relevant decision. We propose a real-time method to acquire, process and register multispectral images fused to 3D. The sensors system, co…

2. Zero hungerImage Registrationbusiness.industryComputer scienceMultispectral imagePoint cloudProcess (computing)ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONImage registration3D Point Cloud[INFO.INFO-CV]Computer Science [cs]/Computer Vision and Pattern Recognition [cs.CV]15. Life on landAgricultural RoboticsField (computer science)Precision viticulturePrecision ViticultureRobotMultispectral ImagingComputer visionArtificial intelligencePrecision agriculturebusiness

Public relations and expectation theory : Introducing Relationship Expectation Theory (RET) for public relations

2021

Expectations provide organizations with information and cues about their stakeholders’ and publics’ values, interests, experiences, and knowledge. This chapter argues for a move that takes expectations beyond the current cursory level for different areas of public relations—reputation management, corporate responsibility, issues management, and legitimacy—toward explicit theoretical understanding and models for addressing expectations. The chapter introduces expectations as an intersecting phenomenon in public relations research and builds postulations for theorizing expectations in public relations by reviewing theories that address expectations in relationships, and by exploring different…

suhdetoimintaexpectanciesyritysvastuuodotuksetsidosryhmätRelationship Expectation Theorymaineenhallintaexpectations

Active and Reactive Value Dimensions: A Dynamic-Based Perspective in the Hotel Sector

2021

Despite the wide acknowledgment of consumer value as a dynamic concept in marketing and tourism literature, few studies have addressed its dynamicity. This article provides an approach to the dynamic nature of value in a hotel experience by proposing a conceptual framework that seeks to explain the influence of value types on customer satisfaction and loyalty as being concatenated rather than simultaneous effects, as more usually described. The concatenation of effects is based on the distinction between active versus reactive values and is tested in a structural model consisting of eight types of value (Efficiency, Service Quality, Status, Esteem, Entertainment, Aesthetics, Ethics, and Es…

MicroeconomicsTourism Leisure and Hospitality Managementmedia_common.quotation_subjectLoyaltyPerspective (graphical)Value (economics)BusinessTourismEducationmedia_commonJournal of Hospitality & Tourism Research

Pooled analysis of monocyte distribution width in subjects with SARS‐CoV‐2 infection

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Clinical BiochemistryLetter to the EditorsMonocytesLeukocyte CountMDWmedicineDistribution (pharmacology)Humansmonocyte distribution widthLetter to the EditorCell SizeBiochemistry medicalbusiness.industrySARS-CoV-2MonocyteBiochemistry (medical)COVID-19Meta-analysis monocyte distribution width MDW SARS-CoV-2HematologyGeneral MedicinePrognosisVirologyMeta-analysisPooled analysismedicine.anatomical_structurebusinessInternational Journal of Laboratory Hematology

Occurrence of Free and Conjugated Mycotoxins in Aromatic and Medicinal Plants and Dietary Exposure Assessment in the Moroccan Population.

2021

Aromatic and medicinal plants (AMPs), as herbal material, are subjected to contamination by various mycotoxin-producing fungi, either free and conjugated. Such a problem is associated with poor storage practices, and lack of adopting good agricultural practices and good harvesting practices. Nevertheless, AMPs are poorly investigated. The purpose of this study was to investigate the co-occurrence of 15 mycotoxins (four aflatoxins (AFB1, AFB2, AFG1, and AFG2), ochratoxin A (OTA), beauvericin (BEA), four enniatins (ENA, ENA1, ENB, and ENB1), zearalenone (ZEN), alternariol (AOH), tentoxin (TENT), T-2, and HT-2 toxins) in 40 samples of AMPs frequently consumed in Morocco by using liquid chromat…

Ochratoxin AAflatoxinSpectrometry Mass Electrospray IonizationHealth Toxicology and MutagenesisPopulationAlternariollcsh:MedicineToxicology01 natural sciencesRisk AssessmentArticleQ-TOF-LC/MSDietary Exposurechemistry.chemical_compound0404 agricultural biotechnologyLiquid chromatography–mass spectrometryTandem Mass Spectrometryco-occurrenceHumansFood scienceeducationMycotoxinZearalenoneeducation.field_of_studyPlants Medicinallcsh:R010401 analytical chemistry04 agricultural and veterinary sciencesMycotoxins040401 food scienceBeauvericin0104 chemical sciencesMoroccochemistryexposureFood MicrobiologyChromatography LiquidToxins

Mediterranean Diet Maintained Platelet Count within a Healthy Range and Decreased Thrombocytopenia-Related Mortality Risk: A Randomized Controlled Tr…

2021

There is little information on the dietary modulation of thrombosis-related risk factors such as platelet count. We aimed to assess the effects of Mediterranean diet (MedDiet) on platelet count and related outcomes in an older population at high cardiovascular risk. In participants of the PREDIMED (PREvención con DIeta MEDiterránea) study, we assessed whether an intervention with a MedDiet enriched with extra-virgin olive oil or nuts, relative to a low-fat control diet, modulated platelet count (n = 4189), the risk of developing thrombocytosis and thrombocytopenia (n = 3086), and the association between these alterations and all-cause mortality (median follow-up time: 3.0 years). Although p…

Male0301 basic medicineMediterranean dietthrombocytopenia030204 cardiovascular system & hematologyDiet Mediterraneanlaw.inventionClinical trials0302 clinical medicinepreventionRandomized controlled triallawPlateletThrombocytosisNutrition and DieteticsFactors de risc en les malaltiesIncidenceIncidence (epidemiology)Hazard ratioFemaleDietalcsh:Nutrition. Foods and food supplymedicine.medical_specialtyRisk factors in diseaseslcsh:TX341-641ArticleOlder population03 medical and health sciencesMediterranean cookingMediterranean dietInternal medicineCuina mediterràniamedicineHumansAgedProportional Hazards ModelsThrombocytosisPlatelet Countbusiness.industryplatelet countmedicine.diseaseConfidence intervalDiet030104 developmental biologyHeart Disease Risk Factorsrandomized controlled trialbusinessAssaigs clínicsFood ScienceNutrients

Photodynamics at the CdSe Quantum Dot–Perylene Diimide Interface: Unraveling the Excitation Energy and Electron Transfer Pathways

2021

Excitation energy and charge transfer processes in perylene diimide dye–CdSe quantum dot complexes have been studied by femtosecond transient absorption spectroscopy. After excitation of the quantu...

Materials sciencePhysics::Optics02 engineering and technologyCondensed Matter::Mesoscopic Systems and Quantum Hall Effect010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialschemistry.chemical_compoundElectron transferGeneral EnergychemistryQuantum dotChemical physicsDiimideFemtosecondUltrafast laser spectroscopyPhysics::Atomic and Molecular ClustersPhysical and Theoretical Chemistry0210 nano-technologySpectroscopyPeryleneExcitationThe Journal of Physical Chemistry C

SARS-CoV-2-specific Cell-mediated Immunity in Kidney Transplant Recipients Recovered From COVID-19.

2021

BACKGROUND: The magnitude and kinetics of severe acute respiratory syndrome coronavirus 2-specific cell-mediated immunity (SARS-CoV-2-CMI) in kidney transplant (KT) recipients remain largely unknown. METHODS: We enumerated SARS-CoV-2-specific interferon-I³-producing CD69+ CD4+ and CD8+ T cells at months 4 and 6 from the diagnosis of coronavirus disease 2019 (COVID-19) in 21 KT recipients by intracellular cytokine staining. Overlapping peptides encompassing the SARS-CoV-2 spike (S) glycoprotein N-terminal 1- to 643-amino acid sequence and the membrane protein were used as stimulus. SARS-CoV-2 IgG antibodies targeting the S1 protein were assessed by ELISA at month 6. RESULTS: Detectable (≥0.1…

AdultCD4-Positive T-LymphocytesGraft RejectionMalemedicine.medical_specialty030230 surgeryCD8-Positive T-LymphocytesAntibodies Monoclonal HumanizedGastroenterology03 medical and health sciencesImmunocompromised HostInterferon-gamma0302 clinical medicineCOVID-19 TestingImmunityInternal medicinemedicineHumansInterferon gammaskin and connective tissue diseasesKidney transplantationAgedTransplantationImmunity Cellularbiologybusiness.industrySARS-CoV-2CD69COVID-19Middle Agedmedicine.diseaseKidney TransplantationTacrolimusTransplant RecipientsCOVID-19 Drug TreatmentMonoclonalbiology.protein030211 gastroenterology & hepatologyFemaleAntibodybusinessCD8Immunosuppressive Agentsmedicine.drugFollow-Up StudiesTransplantation

A High-Performance Asymmetric Supercapacitor Based on Tungsten Oxide Nanoplates and Highly Reduced Graphene Oxide Electrodes.

2021

Tungsten oxide/graphene hybrid materials are attractive semiconductors for energy-related applications. Herein, we report an asymmetric supercapacitor (ASC, HRG//m-WO3 ASC), fabricated from monoclinic tungsten oxide (m-WO3 ) nanoplates as a negative electrode and highly reduced graphene oxide (HRG) as a positive electrode material. The supercapacitor performance of the prepared electrodes was evaluated in an aqueous electrolyte (1 m H2 SO4 ) using three- and two-electrode systems. The HRG//m-WO3 ASC exhibits a maximum specific capacitance of 389 F g-1 at a current density of 0.5 A g-1 , with an associated high energy density of 93 Wh kg-1 at a power density of 500 W kg-1 in a wide 1.6 V ope…

Supercapacitor010405 organic chemistryGrapheneOrganic ChemistryOxideGeneral Chemistry010402 general chemistryElectrochemistry01 natural sciencesCapacitanceCatalysis0104 chemical scienceslaw.inventionchemistry.chemical_compoundchemistryChemical engineeringlawElectrodeHybrid materialCurrent densityChemistry (Weinheim an der Bergstrasse, Germany)

Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis

2021

Background: Knowledge regarding the impact of body composition measures on pharmacokinetics of antipsychotics is limited. Aims: Our aim was to investigate the impact of body weight and body mass index on clozapine pharmacokinetics using a therapeutic drug monitoring database. Methods: A large therapeutic drug monitoring dataset of clozapine plasma concentrations considering three patient subgroups was analysed: a control group (CLZ0, 20–30 kg/m2, n=266), a group with high body mass index (CLZhigh, body mass index ⩾30 kg/m2, n=162) and with low body mass index values (CLZlow, body mass index <20 kg/m2, n=27). Comparisons of plasma and dose-adjusted plasma concentrations (C/D) of clozapine…

AdultMaleBiological AvailabilityPharmacologyBody weightBody Mass IndexYoung Adult03 medical and health sciencesSex Factors0302 clinical medicinePharmacokineticsmedicineHumansTissue DistributionPharmacology (medical)ObesityClozapineClozapineAgedRetrospective StudiesA determinantAged 80 and overPharmacologymedicine.diagnostic_testbusiness.industryBody WeightMiddle Agedmedicine.diseaseObesity030227 psychiatryPsychiatry and Mental healthAdipose TissueLiverTherapeutic drug monitoringPlasma concentrationFemaleDrug MonitoringbusinessBody mass index030217 neurology & neurosurgeryAntipsychotic Agentsmedicine.drugJournal of Psychopharmacology

A review of second‐order blind identification methods

2021

Second-order source separation (SOS) is a data analysis tool which can be used for revealing hidden structures in multivariate time series data or as a tool for dimension reduction. Such methods are nowadays increasingly important as more and more high-dimensional multivariate time series data are measured in numerous fields of applied science. Dimension reduction is crucial, as modeling such high-dimensional data with multivariate time series models is often impractical as the number of parameters describing dependencies between the component time series is usually too high. SOS methods have their roots in the signal processing literature, where they were first used to separate source sign…

Statistics and ProbabilityComputer sciencebusiness.industryDimensionality reductionSecond order blind identificationPattern recognitionArtificial intelligencebusinessBlind signal separationWIREs Computational Statistics

Surface and interface effects on the current-voltage characteristic curves of multiwall carbon nanotube-Si hybrid junctions selectively probed throug…

2021

The possibility to increase the efficiency of photovoltaic (PV) cells based on hybrid carbon nanotube (CNT)–Si heterojunctions is related to the ability to control the chemical properties of the CNT–Si interface and of the CNT bundle layer. In spite of the encouraging performances of PV cells based on multiwall (MW) CNT, so far few efforts have been made in the study of this device compared to single wall (SW) CNT–Si interfaces. Here, surface and interface effects on the current–voltage characteristic curves of MW CNT–Si hybrid junctions are investigated through exposure to HF vapors and to 10 ppm-NO2 and compared to the effects detected in SW CNT–Si junctions. Quite similar results in term…

heterojunctionsMaterials scienceGeneral Physics and Astronomy02 engineering and technologyCarbon nanotubeMultiwalled carbon nanotubesSettore FIS/03 - FISICA DELLA MATERIA01 natural sciencesnanotubeslaw.inventionlawDesorptionEtching0103 physical sciencesMolecule010302 applied physicsSettore FIS/03carbon nanotubesOpen-circuit voltagebusiness.industryPhotovoltaic cellsHeterojunctionSettore ING-INF/02 - Campi Elettromagnetici021001 nanoscience & nanotechnologysolar cellsOptoelectronics0210 nano-technologybusinessShort circuitLayer (electronics)photoemission

Prediction of type 2 diabetes mellitus based on nutrition data

2021

Abstract Numerous predictive models for the risk of type 2 diabetes mellitus (T2DM) exist, but a minority of them has implemented nutrition data so far, even though the significant effect of nutrition on the pathogenesis, prevention and management of T2DM has been established. Thus, in the present study, we aimed to build a predictive model for the risk of T2DM that incorporates nutrition data and calculates its predictive performance. We analysed cross-sectional data from 1591 individuals from the population-based Cooperative Health Research in the Region of Augsburg (KORA) FF4 study (2013–14) and used a bootstrap enhanced elastic net penalised multivariate regression method in order to bu…

Elastic net regularizationFood intakeMultivariate statistics24HFL 24-h food listEndocrinology Diabetes and MetabolismPopulation030209 endocrinology & metabolismType 2 diabetesLogistic regression03 medical and health sciences0302 clinical medicinePredictive Value of TestsRisk FactorsElastic net regressionPrediction modelGermanyStatisticsmedicineHumans030212 general & internal medicineeducationNutritionMathematicseducation.field_of_studyNutrition and DieteticsReceiver operating characteristicDietary Surveys and Nutritional EpidemiologyType 2 Diabetes MellitusType 2 diabetesT2DM type 2 diabetes mellitusmedicine.diseasePPV positive predictive valueDietROC receiver operating characteristicCross-Sectional StudiesNPV negative predictive valueDiabetes Mellitus Type 2ROC CurveKORA Cooperative Health Research in the Region of Augsburg24hfl 24-h Food List ; Elastic Net Regression ; Kora Cooperative Health Research In The Region Of Augsburg ; Npv Negative Predictive Value ; Nutrition ; Ppv Positive Predictive Value ; Prediction Model ; Roc Receiver Operating Characteristic ; T2dmResearch ArticleFood ScienceJournal of Nutritional Science

High efficacy of face masks explained by characteristic regimes of airborne SARS-CoV-2 virus abundance

2021

Abstract Airborne transmission is an important transmission pathway for viruses, including SARS-CoV-2. Regions with a higher proportion of people wearing masks show better control of COVID-19, but the effectiveness of masks is still under debate due to their limited and variable efficiencies in removing respiratory particles. Here, we analyze experimental data and perform model calculations to show that this contrast can be explained by the different regimes of abundance of particles and viruses. Because of the large number of particles exhaled during human respiration and vocalization, indoor environments are usually in a particle-rich regime which means that masks cannot prevent the inhal…

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virusesfungiAtmospheric sciencesAirborne transmissionViruslaw.inventionAerosolFace masksOrders of magnitude (bit rate)Transmission (mechanics)lawAbundance (ecology)Environmental science

Simvastatin in vitiligo: an update with recent review of the literature.

2021

Patients with vitiligo often seek medical attention, as it diminishes their quality of life resulting in significant morbidity. Several topical and systemic therapies are in vogue targeting the immunological aspect of this disease, but results are often unsatisfactory, and complete cure remains elusive. Recently, simvastatin, a 3-hydroxy-3-methylyglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, is being evaluated for vitiligo management because of its multimodal action, easy availability, and low cost. The proposed multimodal actions range from anti-inflammatory, antioxidant, to immunomodulatory properties which may be of therapeutic benefit in vitiligo patients. The authors intend to eva…

medicine.medical_specialtySimvastatinintegumentary systembusiness.industryVitiligoDermatologyDiseaseVitiligomedicine.disease030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineQuality of lifeSimvastatin030220 oncology & carcinogenesismedicineQuality of LifeHumansHydroxymethylglutaryl-CoA Reductase Inhibitorsskin and connective tissue diseasesIntensive care medicinebusinessMedical attentionmedicine.drugInternational journal of dermatologyReference

Life-Cycle Land-Use Requirement for PV in Vietnam

2021

Over the last 15 years, photovoltaics (PV) in Vietnam has experienced development. The increased installed capacity of PV requires more land for installation sites as well as for manufacturing the plants’ component and waste treatment during the plants’ decommissioning. As a developing country, in which more than 80% of the population’s livelihood depends on agriculture, there are concerns about the competition of land for agriculture and solar development. This paper estimates the life-cycle land-use requirement for PV development in Vietnam, to provide the scientific-based evidence for policy makers on the quantity of land required, so that the land budget can be suitably allocated. The d…

Control and Optimization020209 energyPopulationEnergy Engineering and Power TechnologyDeveloping country02 engineering and technology010501 environmental scienceslcsh:Technology01 natural sciencesAgricultural economicsNuclear decommissioningCompetition (economics)0202 electrical engineering electronic engineering information engineeringElectrical and Electronic EngineeringeducationEngineering (miscellaneous)0105 earth and related environmental scienceseducation.field_of_studyLand uselcsh:TRenewable Energy Sustainability and the Environmentbusiness.industrylife cycle thinking and photovoltaic systemLivelihoodNameplate capacityAgricultureLand useBusinessEnergy (miscellaneous)Energies

Global connectivity between commodity prices and national stock markets: A time‐varying MIDAS analysis

2021

Economics and EconometricsAccountingCommodityEconomicsMonetary economicsEmerging marketsFinanceStock (geology)International Journal of Finance & Economics

Amplitude analysis and branching-fraction measurement of $D^{+}_{s}\rightarrow K^{0}_{S}K^{-}\pi^{+}\pi^{+}$

2021

Using 6.32 fb$^{-1}$ of $e^+e^-$ collision data collected by the BESIII detector at the center-of-mass energies between 4.178 and 4.226 GeV,~an amplitude analysis of the $D^{+}_{s}\rightarrow K^{0}_{S}K^{-}\pi^{+}\pi^{+}$ decays is performed for the first time to determine the intermediate-resonant contributions. The dominant component is the $D_s^+ \to K^*(892)^+\overline{K}^*(892)^0$ decay with a fraction of $(40.6\pm2.9_{\rm stat}\pm4.9_{\rm sys})$%. Our results of the amplitude analysis are used to obtain a more precise measurement of the branching fraction of the $D^{+}_{s}\rightarrow K^{0}_{S}K^{-}\pi^{+}\pi^{+}$ decay, which is determined to be $(1.46\pm0.05_{\rm stat}\pm0.05_{\rm sy…

High Energy Physics - Experiment

Introduction to Mathematical Logic, Edition 2021

2021

Textbook for students in mathematical logic. First order languages. Axioms of constructive and classical logic. Proving formulas in propositional and predicate logic. Glivenko's theorem and constructive embedding. Axiom independence. Interpretations, models and completeness theorems. Normal forms. Tableaux and resolution methods. Herbrand's theorem. Sections 1, 2, 3 represent an extended translation of the corresponding chapters of the book: V. Detlovs, Elements of Mathematical Logic, Riga, University of Latvia, 1964, 252 pp. (in Latvian).

resolution methodHerbrand's theoremmodel theoryComputer Science::Logic in Computer Sciencepredicate logicmathematical logic:MATHEMATICS::Algebra geometry and mathematical analysis::Mathematical logic [Research Subject Categories]propositional logictableaux methodcompleteness theorems

Aspectos prácticos de la prueba pericial en el orden social

2021

El objeto de este artículo es abordar determinadas cuestiones relacionadas con la prueba pericial, que es utilizada en todo tipo de pleitos de incapacidad, minusvalía, accidentes de trabajo, despido y acoso, entre otros. Se tratará de perfilar algunas cuestiones prácticas sobre la proposición, admisión, práctica y valoración de las periciales médicas, informáticas, caligráficas o cuestionarios psicológicos, que pueden presentar especificidades en el orden social. Abstract The purpose of this article is to address certain issues related to expert evidence, which is used in all types of disability, handicap, work-related accidents, dismissal, harassment, among others. It will try to outline s…

Dret del treballRevista de Trabajo y Seguridad Social. CEF

Professional activism in journalism and education in gender equality through Twitter

2021

This article analyses professional activism by women journalists' organisations which, through their Twitter accounts, contribute to extend the value of equality between men and women, which is activism that embodies the ethical or deontological codes of this profession. The tweets of these groups not only propose improvements in the expression and writing of news, after reporting biased, stereotypical or denigrating uses of language by large Spanish media, but also recognise and applaud contents that dignify women or place them in the public sphere that they deserve. A content analysis methodology was followed by applying both quantitative and qualitative analyses to a sample of 7,424 twee…

Gender equalityVisual Arts and Performing ArtsCommunicationeducation05 social sciences050801 communication & media studiesGender studiesÈtica periodísticahumanitiesXarxes socialsGender Studies0508 media and communicationsPeriodisme050903 gender studiesJournalismSociology0509 other social sciencesValue (mathematics)Feminist Media Studies

Editorial: ‹Digitale Bildung›

2021

General MedicineMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung