showing 36 of ~574560 from 574555 documents
It is hard to forget what comes around: Time‐lagged effects of employers' non‐fulfillment of psychological contract
2021
NVMM-Oriented Hierarchical Persistent Client Caching for Lustre
2021
In high-performance computing (HPC), data and metadata are stored on special server nodes and client applications access the servers’ data and metadata through a network, which induces network latencies and resource contention. These server nodes are typically equipped with (slow) magnetic disks, while the client nodes store temporary data on fast SSDs or even on non-volatile main memory (NVMM). Therefore, the full potential of parallel file systems can only be reached if fast client side storage devices are included into the overall storage architecture. In this article, we propose an NVMM-based hierarchical persistent client cache for the Lustre file system (NVMM-LPCC for short). NVMM-LPC…
Games and Bisimulations for Intuitionistic First-Order Kripke Models
2021
The aim of this paper is to introduce the notion of a game for intuitionisticfirst-order Kripke models. We also establish links between notions presented here and thenotions of logical equivalence and bounded bisimulation for intuitionistic first-order Kripkemodels, and the Ehrenfeucht–Fra ̈ıss ́e game for classical first-order structures.
Body Mass Index in Patients Treated with Cabozantinib for Advanced Renal Cell Carcinoma: A New Prognostic Factor?
2021
We analyzed the clinical and pathological features of renal cell carcinoma (RCC) patients treated with cabozantinib stratified by body mass index (BMI). We retrospectively collected data from 16 worldwide centers involved in the treatment of RCC. Overall survival (OS) and progression-free survival (PFS) were analyzed using Kaplan&ndash
GrailQuest & HERMES: Hunting for Gravitational Wave Electromagnetic Counterparts and Probing Space-Time Quantum Foam
2021
GrailQuest (Gamma-ray Astronomy International Laboratory for Quantum Exploration of Space-Time) is an ambitious astrophysical mission concept that uses a fleet of small satellites whose main objective is to search for a dispersion law for light propagation in vacuo. Within Quantum Gravity theories, different models for space-time quantization predict relative discrepancies of the speed of photons w.r.t. the speed of light that depend on the ratio of the photon energy to the Planck energy. This ratio is as small as 1E-23 for photons in the gamma-ray band (100 keV). Therefore, to detect this effect, light must propagate over enormous distances and the experiment must have extraordinary sensit…
Cover Picture: Asymmetric Oxidative Mannich Reactions (Adv. Synth. Catal. 3/2021)
2021
Glucagon-Like Peptide 1 and Taste Perception: From Molecular Mechanisms to Potential Clinical Implications
2021
Preclinical studies provided some important insights into the action of glucagon-like peptide 1 (GLP-1) in taste perception. This review examines the literature to uncover some molecular mechanisms and connections between GLP-1 and the gustatory coding. Local GLP-1 production in the taste bud cells, the expression of GLP-1 receptor on the adjacent nerves, a functional continuum in the perception of sweet chemicals from the gut to the tongue and an identification of GLP-1 induced signaling pathways in peripheral and central gustatory coding all strongly suggest that GLP-1 is involved in the taste perception, especially sweet. However, the impact of GLP-1 based therapies on gustatory coding i…
The Bias toward the Right Side of Others Is Stronger for Hands than for Feet
2021
As shown by a series of previous studies, ambiguous human bodies performing unimanual or unipedal actions tend to be perceived more frequently as right-handed or right-footed rather than left-handed or left-footed, which indicates a perceptual and attentional bias toward the right side of others&rsquo
In the name of security : Governmentality apparatus in a multilingual mine in Arctic Finland
2021
This critical sociolinguistic study explores how mining work is governed in the name of security in a mine in Arctic Finland. Although the mining industry is dominated by multinational corporations, mines themselves tend to be concentrated in peripheries where a mobile and multilingual workforce is recruited. Mining is a high-risk business: industrial accidents and environmental damage can be severe. Discursive practices play a crucial role in risk management. In this study, the nexus of language, security, and production in mining work is analyzed by applying the Foucauldian concept of 'governmentality'. The data comprise ethnographic observations, work-related documents, and interviews co…
Personal and Environmental Risk Factors at Birth and Hospital Admission: Direct and Vitamin D-Mediated Effects on Bronchiolitis Hospitalization in It…
2021
Seasonal variations in UV-B radiation may influence vitamin D status, and this, in turn, may influence the risk of bronchiolitis hospitalization. The aim of this study was using a causal inference approach to investigate, simultaneously, the interrelationships between personal and environmental risk factors at birth/hospital admission (RFBH), serum vitamin D levels and bronchiolitis hospitalization. A total of 63 children (<
Comparison of DMEK and DSAEK in Eyes With Endothelial Decompensation After Previous Penetrating Keratoplasty.
2021
PURPOSE Posterior lamellar keratoplasty is increasingly applied in patients with endothelial decompensation after penetrating keratoplasty (PK). The aim of this study was to compare the results of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) after PK. METHODS In this retrospective study, clinical data of 30 patients who received DMEK (n = 19) or DSAEK (n = 11) for endothelial decompensation after PK were evaluated. All lamellar keratoplasties were performed at the Department of Ophthalmology at University Hospital Mainz, Germany. Primary end point included best-corrected visual acuity, and secondary end points included e…
Cognitive and Physical Activity-Related Aspects of Children Associated to the Performance of the Crunning Movement
2021
The aim of this investigation was to identify possible related factors associated to the performance of the crunning test in European children and adolescents. A total number of 559 children and adolescents (age range 6&ndash
Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of Different Coffee Brews Chemically Profiled through UHPLC-Q-Orbitrap HRMS
2021
Coffee represents one of the most traditionally consumed beverages worldwide, containing a broad range of human health&ndash
Helminth Microbiota Profiling Using Bacterial 16S rRNA Gene Amplicon Sequencing: From Sampling to Sequence Data Mining
2021
Symbiont microbial communities play important roles in animal biology and are thus considered integral components of metazoan organisms, including parasitic worms (helminths). Nevertheless, the study of helminth microbiomes has thus far been largely overlooked, and symbiotic relationships between helminths and their microbiomes have been only investigated in selected parasitic worms. Over the past decade, advances in next-generation sequencing technologies, coupled with their increased affordability, have spurred investigations of helminth-associated microbial communities aiming at enhancing current understanding of their fundamental biology and physiology, as well as of host-microbe intera…
Imaging of calcified hepatic lesions: spectrum of diseases
2021
Hepatic calcifications have been increasingly identified over the past decade due to the widespread use of high-resolution Computed Tomography (CT) imaging. Calcifications can be seen in a vast spectrum of common and uncommon diseases, from benign to malignant, including cystic lesions, solid neoplastic masses, and inflammatory focal lesions. The purpose of this paper is to present an updated review of CT imaging findings of a wide range of calcified hepatic focal lesions, which can help radiologists to narrow the differential diagnosis.
On stability of logarithmic tangent sheaves. Symmetric and generic determinants
2021
We prove stability of logarithmic tangent sheaves of singular hypersurfaces D of the projective space with constraints on the dimension and degree of the singularities of D. As main application, we prove that determinants and symmetric determinants have stable logarithmic tangent sheaves and we describe an open dense piece of the associated moduli space.
First Report of X-Linked Hypohidrotic Ectodermal Dysplasia with a Hemizygous c.1142G &gt;C in the EDA Gene: Variant of Uncertain Significance or …
2021
Abstract BackgroundHypohidrotic Ectodermal Dysplasia (HED) is a genetic disorder which affects structures of ectodermal origin. X-linked hypohidrotic ectodermal dysplasia (XLHED) is the most common form of disease. XLHED Is characterized by hypotrichosis, hypohydrosis and hypodontia. The cardinal features of classic HED become obvious during childhood. Identification of a hemizygous EDA pathogenic variant in an affected male confirms the diagnosis. Case PresentationWe report on a male newborn with the main clinical characteristics of the X-linked HED including hypotrichosis, hypodontia and hypohidrosis. Gene panel sequencing identified a new hemizygous missense variant of uncertain signific…
Thymic Hyperplasia with Lymphoepithelial Sialadenitis (LESA)-Like Features: Strong Association with Lymphomas and Non-Myasthenic Autoimmune Diseases.
2021
Thymic hyperplasia (TH) with lymphoepithelial sialadenitis (LESA)-like features (LESA-like TH) has been described as a tumor-like, benign proliferation of thymic epithelial cells and lymphoid follicles. We aimed to determine the frequency of lymphoma and autoimmunity in LESA-like TH and performed retrospective analysis of cases with LESA-like TH and/or thymic MALT-lymphoma. Among 36 patients (21 males) with LESA-like TH (age 52 years, 32&ndash
Impacts of land‐use changes on soil fertility in Okomu Forest Reserve, Southern Nigeria
2021
Searching the Traces of Middle Low German in Latvian Proper Names
2021
Searching the traces of Middle Low German in Latvian proper names The great impact of Middle Low German on the Latvian language during the 13 th –16 th centuries is a well-known and rather widely researched fact. However, the main focus of linguists’ attention has so far been on the apellative vocabulary. This article therefore aims to highlight the traces of Middle Low German in Latvian proper names – placenames and personal names (both first names and surnames) – during the time of their appearance and also nowadays (also touching upon the issue of onyms that have disappeared during previous centuries). The system of Latvian personal names (as the ancient Baltic two-stem personal names gr…
Cover Crop and Pruning Residue Management to Reduce Nitrogen Mineral Fertilization in Mediterranean Vineyards
2021
This paper aimed to study the effect of temporary cover crop and vine pruning residue burial as alternative practices to conventional tillage on soil nitrate (NO3-N) availability and grapevine performance in the short term. The trial was carried out in a rain-fed vineyard (Vitis vinifera L., cv Grecanico dorato/140 Ruggeri) located in a traditional Mediterranean viticultural area (37°
Tooth tales told by dental diet proxies: An alpine community of sympatric ruminants as a model to decipher the ecology of fossil fauna
2021
Abstract Paleobiologists tend to use dietary information as an ecological indicator because diet is a fundamental link between an organism and its environment. However, the ecological information from fossilized hard tissues is often difficult to interpret, because links between environment, diet, and hard tissue biology are insufficiently studied in modern communities. To address this dilemma, we investigated dietary proxies commonly used by paleobiologists in a 4-ruminant community from the French Alps. Dental microwear texture analyses are applied to 82 specimens of roe deer, red deer, chamois, and mouflons. Intra-tooth serial enamel stable carbon and oxygen isotope analyses of the struc…
Tillage Impacts on Initial Soil Erosion in Wheat and Sainfoin Fields under Simulated Extreme Rainfall Treatments
2021
The main aim of this research was to determine the potential effects of different tillage systems (TT: traditional tillage and RT: reduced tillage) on runoff and erosion at two different locations (Kahramanmaras and Tarsus, Southern Turkey) under (i) fallow, (ii) wheat (Triticumaestivum L.), and (iii) sainfoin (Onobrychissativa L.) crops. Rainfall simulations with intensity of 120 mm h&minus
Composite Material Recycling Technology—State-of-the-Art and Sustainable Development for the 2020s
2021
Recently, significant events took place that added immensely to the sociotechnical pressure for developing sustainable composite recycling solutions, namely (1) a ban on composite landfilling in Germany in 2009, (2) the first major wave of composite wind turbines reaching their End-of-Life (EoL) and being decommissioned in 2019–2020, (3) the acceleration of aircraft decommissioning due to the COVID-19 pandemic, and (4) the increase of composites in mass production cars, thanks to the development of high volume technologies based on thermoplastic composites. Such sociotechnical pressure will only grow in the upcoming decade of 2020s as other countries are to follow Germany by limiting and ba…
A bottom-up harmonized energy-environmental models for europe (BOHEEME): A case study on the thermal insulation of the EU-28 building stock
2021
Abstract The paper presents a methodological approach, called “BOttom-up Harmonized Energy-Environmental Models for Europe” (BOHEEME), that combines bottom-up modeling, energy dynamic simulation, and life cycle assessment for evaluating and comparing the energy and environmental effects of different renovation strategies of the residential EU building stocks, from micro to the macro level. The study defines 672 building models representative of the residential EU-28 building stocks built before 2010, called archetypes, and the improvement of their envelope, applying different insulation materials from a traditional one to bio-based materials and studying their environmental effects via LCA.…
Efficacy of Computer-Aided Static Navigation Technique on the Accuracy of Endodontic Microsurgery. A Systematic Review and Meta-Analysis
2021
The aim of this systematic review and meta-analysis was to analyze the efficacy of the computer-aided static navigation technique on the accuracy of root apex location in endodontic microsurgery. Material and Methods: A systematic literature review and meta-analysis, based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, of clinical studies that evaluated the apex location rate of the computer-aided static navigation techniques applied to endodontic microsurgery. A total of four databases were consulted in the literature search: Pubmed-Medline, Scopus, Cochrane, and Web of Science. After eliminating duplicated articles and applying the inclusio…
A retrospective analysis of oral and maxillofacial lesions in children and adolescents reported in two different services.
2021
Background Most epidemiological studies involving oral and maxillofacial lesions assess only data from histopathological analysis. This may lead to a poor notification of diseases whose diagnosis is predominantly clinical. Aim: To evaluate and to compare the frequency of oral and maxillofacial lesions in children and adolescents in two different types of services: Oral Medicine clinic service and laboratory service. Material and methods The records of patients ≤ 19 years attending the Oral Medicine clinic service and records from the laboratory service in Oral and Maxillofacial Pathology of the Dental School of a university were analyzed. Results 828 records from the Oral Medicine clinic se…
femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein: dark structure of photoactive yellow protein
2021
A Survey of Active Learning for Quantifying Vegetation Traits from Terrestrial Earth Observation Data
2021
The current exponential increase of spatiotemporally explicit data streams from satellite-based Earth observation missions offers promising opportunities for global vegetation monitoring. Intelligent sampling through active learning (AL) heuristics provides a pathway for fast inference of essential vegetation variables by means of hybrid retrieval approaches, i.e., machine learning regression algorithms trained by radiative transfer model (RTM) simulations. In this study we summarize AL theory and perform a brief systematic literature survey about AL heuristics used in the context of Earth observation regression problems over terrestrial targets. Across all relevant studies it appeared that…
Spațiul sacru în biserica creștină de tradiție bizantină. Trei perspective
2021
The creation of sacred spaces has played a central role during the evolution of christian faith and culture. The main source of inspiration has been the word of the Bible which describes the design of the Holy Place as told by God to the chosen ones at various times. The divine models have been filled with symbolic meanings by Holy Fathers and Byzantine theologians. Thus, the understanding of their writings and the Holy Bible come first when analysing the sacred spaces of the Eastern Church. This article presents the main concepts regarding the Church, it’s architecture and spiritual meaning, of three Byzantine thinkers – Dionysius the Areopagite, Maximus the Confessor and Symeon of Thessal…
Teritorii deținute de ordinele militaro-religioase în părțile răsăritene ale regatului arpadian în secolul al XIII-lea
2021
At the beginning of the 13th century the Hungarian kingdom was defining its eastern and south-eastern borders. In that period the regions of Transylvania and Banat where frequent subjected to raids undertaken by the Cumans. The Hungarian kings understood the importance of those two border regions and invited, at first, the Teutonic Order to settle in the Burzenland and then the Order of the Knights Hospitaller in the Banate of Severin to protect these key regions. This paper tries to present, if it is the case, the evolution and the relationship of these two orders within the medieval Hungarian administrative system.
Strain Release Chemistry of Photogenerated Small‐Ring Intermediates
2021
Abstract Photochemical processes, such as isomerizations and cycloadditions, have proven to be very useful in the construction of highly strained molecular frameworks. Photoinduced ring strain enables subsequent exergonic reactions which do not require the input of additional chemical energy and provides a variety of attractive synthetic options leading to complex structures. This review covers the progress achieved in the application of sequences combining excitation by ultraviolet light to form strained intermediates, which are further transformed to lower energy products in strain‐release reactions. As ring strain is considerable in small ring systems, photogenerated three‐ and four‐memb…
Ceftolozane-Tazobactam Combination Therapy Compared to Ceftolozane-Tazobactam Monotherapy for the Treatment of Severe Infections: A Systematic Review…
2021
Ceftolozane-tazobactam (C/T) is a combination of an advanced-generation cephalosporin (ceftolozane) with a &beta
Greater mitochondrial energy production provides resistance to ocean acidification in "winning" hermatypic corals
2021
Coral communities around the world are projected to be negatively affected by ocean acidification. Not all coral species will respond in the same manner to rising CO2 levels. Evidence from naturally acidified areas such as CO2 seeps have shown that although a few species are resistant to elevated CO2, most lack sufficient resistance resulting in their decline. This has led to the simple grouping of coral species into “winners” and “losers,” but the physiological traits supporting this ecological assessment are yet to be fully understood. Here using CO2 seeps, in two biogeographically distinct regions, we investigated whether physiological traits related to energy production [mitochondrial e…
The refugee entrepreneurship process from/in emerging economies
2021
The paper examines several refugee experiences in Mexico and presents their reasons for leaving their home countries. A gap in research is identifying the entrepreneurial process experienced by refugee entrepreneurs. We use the case study of 10 Latin American refugees in Mexico to propose a conceptual framework that describes the entrepreneurial process of refugee entrepreneurs. We have found that this process begins with the abandonment of the country of origin, followed by the traumatic experiences that caused flight and the difficulties they face in the pilgrimage to the host country. These events help shape the entrepreneurial intention of the refugees.
Orienter les choix vers des alternatives plus saines pour le goûter
2021
National audience