showing 36 of ~574560 from 574555 documents
Differential impact of COVID-related lockdown on mental health in Germany.
2021
Statement of the Prolamin Working Group on the Determination of Gluten in Fermented Foods Containing Partially Hydrolyzed Gluten
2021
On August 12, 2020, the U.S. Food and Drug Administration (FDA) has finalized a rule related to gluten-free labeling for foods containing fermented, hydrolyzed ingredients. The FDA believes that there is no scientifically valid analytical method effective for determining gluten in fermented or hydrolyzed foods. In the absence of an analytical method, the FDA has decided to evaluate gluten-free claims on these foods based only on evidence that the food or ingredient used is gluten-free before fermentation or hydrolysis. For example, barley-based beers from which gluten is removed during brewing using special filtration, adsorption and/or enzymatic treatment are therefore excluded from bearin…
Nitric Oxide/Cyclic Guanosine Monophosphate Signaling via Guanylyl Cyclase Isoform 1 Mediates Early Changes in Synaptic Transmission and Brain Edema …
2021
Traumatic brain injury (TBI) often induces structural damage, disruption of the blood-brain barrier (BBB), neurodegeneration, and dysfunctions of surviving neuronal networks. Nitric oxide (NO) signaling has been suggested to affect brain functions after TBI. The NO exhibits most of its biological effects by activation of the primary targets-guanylyl cyclases (NO-GCs), which exists in two isoforms (NO-GC1 and NO-GC2), and the subsequently produced cyclic guanosine monophosphate (cGMP). However, the specific function of the NO-NO-GCs-cGMP pathway in the context of brain injury is not fully understood. To investigate the specific role of the isoform NO-GC1 early after brain injuries, we perfor…
Effects of an Educational Hybrid Physical Education Program on Physical Fitness, Body Composition and Sedentary and Physical Activity Times in Adoles…
2021
Physical activity (PA), body composition and sedentary behavior may affect the health of children. Therefore, this study examined the effect of an educational hybrid physical education (PE) program on physical fitness (PF), body composition and sedentary and PA times in adolescents. A 9-month group-randomized controlled trial was conducted in 150 participants (age: 14.63 ± 1.38 years) allocated into the control group (CG,n= 37) and experimental group (EG,n= 113). Cardiorespiratory fitness, speed, strength, agility, flexibility and body mass index (BMI) were assessed through previously validated field tests. Sedentary time, PA at school and afterschool were evaluated with the Youth Activity …
Transcultural Adaptation and Theoretical Models of Validation of the Spanish Version of the Self-Care of Heart Failure Index Version 6.2 (SCHFI v.6.2)
2021
Background: Heart failure (HF) is a major and growing public health problem worldwide. Across the world, heart failure is associated with high mortality, high hospitalization rates, and poor quality of life. Self-care is defined as a naturalistic decision-making process involving the choice of behaviors that maintain physiologic stability, the response to symptoms when they occur, and the ability to follow the treatment regimen and control symptoms. One instrument used to measure self-care is the Self Care of Heart Failure Index. Aim: The purpose of this study was to test the psychometric properties of the Spanish version of the Self Care of Heart Failure Index v.6.2 (SCHFI v.6.2). Methodol…
A Review of the Water Desalination Technologies
2021
Desalination is commonly adopted nowadays to overcome the freshwater scarcity in some areas of the world if brackish water or salt water is available. Different kinds of technologies have been proposed in the last century. In this paper, the state of the mainstream solutions is reported, showing the current commercial technologies like reverse osmosis (RO), Multi-Stages Flash desalination (MSF) and Multi-Effect Distillation (MED), and the new frontiers of the research with the aim of exploiting renewable sources such as wind, solar and biomass energy. In these cases, seawater treatment plants are the same as traditional ones, with the only difference being that they use a renewable energy s…
Effect of linker distribution in the photocatalytic activity of multivariate mesoporous crystals
2021
The use of Metal-Organic Frameworks as crystalline matrices for the synthesis of multiple component or multivariate solids by the combination of different linkers into a single material has emerged as a versatile route to tailor the properties of single-component phases or even access new functions. This approach is particularly relevant for Zr6-MOFs due to the synthetic flexibility of this inorganic node. However, the majority of materials are isolated as polycrystalline solids, which are not ideal to decipher the spatial arrangement of parent and exchanged linkers for the formation of homogeneous structures or heterogeneous domains across the solid. Here we use high-throughput methodologi…
Are small protected habitat patches within boreal production forests effective in conserving species richness, abundance and community composition? :…
2021
Abstract Background In boreal zone forest management is changing and degrading forest habitats, which has caused declines in biodiversity. To mitigate these harmful effects in production forests, small-scale habitats with high biodiversity values have been protected within them. These habitats include woodland key habitats, and other small habitat patches protected by voluntary conservation actions. In this systematic review we synthesize the evidence on the value of small protected habitat patches (SPHP) within production forest landscapes for biodiversity. Review question: Are small protected habitat patches within boreal production forests effective in conserving species richness, abunda…
false
2021
Every organism has an intrinsic biological rhythm that orchestrates biological processes in adjusting to daily environmental changes. Circadian rhythms are maintained by networks of molecular clocks throughout the core and peripheral tissues, including immune cells, blood vessels, and perivascular adipose tissues. Recent findings have suggested strong correlations between the circadian clock and cardiovascular diseases. Desynchronization between the circadian rhythm and body metabolism contributes to the development of cardiovascular diseases including arteriosclerosis and thrombosis. Circadian rhythms are involved in controlling inflammatory processes and metabolisms, which can influence t…
The hierarchy of needs for user experiences in virtual reality
2021
Virtual reality (VR) is rapidly becoming more widely adopted by various industries, and virtual content is just as rapidly becoming available for consumers. However, there is a lack of guidelines and standards for VR content to be held to in terms of experiential design. Because VR is a relatively new media form for consumers, there is a high risk of user attrition due to the novelty of the service. Therefore, if the first experience of the technology is with poorly made content, users will be much less likely to use VR again. Therefore, as various industries and organizations digitalize and adopt emerging technology such as VR, great care should be given to the way the virtual content and …
Public opinion, media and activism: the differentiating role of media use and perceptions of public opinion on political behaviour
2021
To what extent do perceptions of public opinion effect individual support and political participation in political action? To what extent might media use moderate the role of public opinion in pred...
Morphology and Band Structure of Orthorhombic PbS Nanoplatelets: An Indirect Band Gap Material
2021
PbS quantum dots and nanoplatelets (NPLs) are of enormous interest in the development of optoelectronic devices. However, some important aspects of their nature remain unclear. Recent studies have revealed that colloidal PbS NPLs may depart from the rock-salt crystal structure of bulk and form an orthorhombic (Pnma) modification instead. To gain insight into the implications of such a change over the optoelectronic properties, we have synthesized orthorhombic PbS NPLs and determined the lattice parameters by means of selected area electron diffraction measurements. We have then calculated the associated band structure using density functional theory with Perdew–Burke–Ernzerhof functional fo…
Probing photophobic axion and relaxion dark matter
2021
We investigate the interplay between early universe cosmology and dark matter direct detection, considering axion models with naturally suppressed couplings to photons. In the context of the cosmological relaxation of the electroweak scale, we focus on a scenario of relaxion dark matter, in which the relaxion field constitutes all the observed dark matter relic density and its allowed mass range is fixed to a few keV by construction. In particular, we show that a relaxion particle with mass mϕ=3.0 keV which couples to electrons with gϕ,e=6.8×10−14 is consistent with the XENON1T excess, while accounting for the observed dark matter and satisfying astro/cosmo probes. This scenario uses the el…
Predictive and Prognostic Molecular Factors in Diffuse Large B-Cell Lymphomas.
2021
Diffuse large B-cell lymphoma (DLBCL) is the commonest form of lymphoid malignancy, with a prevalence of about 40% worldwide. Its classification encompasses a common form, also termed as “not otherwise specified” (NOS), and a series of variants, which are rare and at least in part related to viral agents. Over the last two decades, DLBCL-NOS, which accounts for more than 80% of the neoplasms included in the DLBCL chapter, has been the object of an increasing number of molecular studies which have led to the identification of prognostic/predictive factors that are increasingly entering daily practice. In this review, the main achievements obtained by gene expression profiling (with respect t…
Unraveling the In Vivo Protein Corona
2021
Understanding the behavior of nanoparticles upon contact with a physiological environment is of urgent need in order to improve their properties for a successful therapeutic application. Most commonly, the interaction of nanoparticles with plasma proteins are studied under in vitro conditions. However, this has been shown to not reflect the complex situation after in vivo administration. Therefore, here we focused on the investigation of magnetic nanoparticles with blood proteins under in vivo conditions. Importantly, we observed a radically different proteome in vivo in comparison to the in vitro situation underlining the significance of in vivo protein corona studies. Next to this, we fou…
Psychological Impact on the Nursing Professionals of the Rioja Health Service (Spain) Due to the SARS-CoV-2 Virus
2021
Background: The COVID-19 pandemic is a public health emergency that has affected health professionals around the world, causing physical and mental exhaustion with a greater probability of developing mental disorders in professionals who provide healthcare. Objective: The objective of this study was to know the psychological impact of the SARS-CoV-2 virus on the nursing professionals working for the Rioja Health Service. Methods: We conducted an observational and descriptive cross-sectional study. The nursing staff at the Rioja Health Service were invited to respond to a self-administered questionnaire between June and August 2020. Results: A total of 605 health professionals participated i…
Immersive gaming as journalism
2021
This chapter discusses immersion and how it may be applied to journalism. It begins by unraveling the concept of immersion itself as a reminder that it is not only connected to virtual reality or augmented reality technologies, but rather that it is a multifaceted concept that may be understood in many ways. The chapter turns specifically to the theorizing done in the context of digital games research, where immersion and some related concepts have been explored in detail over the last decades. This theorizing helps us see how immersion can be understood and in what way the concept may be problematic. The chapter maps out some of the historical precedents for immersion, discusses alternativ…
Florence Nightingale and the Spanish nursing school of Santa Isabel De Hungría (1896).
2021
PURPOSE The Spanish surgeon Federico Rubio-Gali worked at St. Thomas Hospital in England at the time when Florence Nightingale founded the Nightingale Training School for Nurses (1860). Apparently, he was quite aware of Nightingale's nursing work and expertise and it is known that founded the first Spanish nursing school, in Madrid, in 1896. This led us to wonder if the emergence of his school was purely by chance or was connected to what its founder learned in England. Likely, this learned knowledge led him to apply Nightingale's ideas and to put them into practice in his institution. METHODS We used content analysis techniques and developed categories and subcategories to search for ideol…
The impact of emotions in immersive journalism
2021
One of the starting motivations for developing the very concept and practice of immersive journalism was concern about the audiences’ general apathy toward news reporting. As Nonny de la Peña et al. (2010, 298) stated in their seminal paper, “An important role of immersive journalism could be to reinstitute the audience’s emotional involvement in current events”. As a documentarist, de la Peña was more familiar with “emotional literacy” than an average news reporter, for example (see Pantti 2010, 176). peerReviewed
Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related…
2021
Extracellular vesicles (EVs) mediate cell-to-cell crosstalk whose content can induce changes in acceptor cells and their microenvironment. MLP29 cells are mouse liver progenitor cells that release EVs loaded with signaling cues that could affect cell fate. In the current work, we incubated 3T3-L1 mouse fibroblasts with MLP29-derived EVs, and then analyzed changes by proteomics and transcriptomics. Results showed a general downregulation of protein and transcript expression related to proliferative and metabolic routes dependent on TGF-beta. We also observed an increase in the ERBB2 interacting protein (ERBIN) and Cxcl2, together with an induction of ribosome biogenesis and interferon-relate…
Effects of Onshore and Offshore Environmental Parameters on the Leading Edge Erosion of Wind Turbine Blades: A Comparative Study
2021
Abstract The presence of rain-induced leading edge erosion of wind turbine blades (WTBs) necessitates the development of erosion models. One of the essential parameters for erosion modeling is the relative impact velocity between rain droplets and the rotating blade. Based on this parameter, the erosion damage rate of a WTB is calculated to estimate the expected leading edge lifetime. The environmental conditions that govern this parameter have site-specific variations, and thus, rain and wind loading on a turbine differ for onshore and offshore locations. In addition, there are wave loads present in the offshore environment. The present paper tries to provide guidelines for erosion modelin…
Sensor Node Network for Remote Moisture Measurement in Timber Based on Bluetooth Low Energy and Web-Based Monitoring System
2021
This paper proposes an IoT system based on wireless BLE connectivity to monitor the moisture content of wood, using a compact and low-cost moisture device that relies on a resistance measurement method valid for an ultra-wide range of resistance values. This device is digitally controlled with a BLE-incorporated micro-controller characterized by its small size and low power consumption, providing long-life battery. The proposed system consists of two main parts: first, the BLE moisture device including the moisture content measurement and wireless capability (BLE)
Face mask use in the Community for Reducing the Spread of COVID-19: a systematic review
2021
ABSTRACTBackgroundEvidence is needed on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.MethodsSystematic review and meta-analysis to investigate the efficacy and effectiveness of face mask use in a community setting and to predict the effectiveness of wearing a mask. We searched MEDLINE, EMBASE, SCISEARCH, The Cochrane Library and pre-prints from inception to 22 April 2020 without restriction by language. We rated the certainty of evidence according to Cochrane and GRADE approach.FindingsOur search identified 35 studies, including 3 randomised controlled trials (RCTs) (4017 patients), 10 comparative studies (18984 patients), 13 predictive models,…
Diabatic description of charmoniumlike mesons. II. Mass corrections and strong decay widths
2021
From a diabatic bound state approach to $J^{PC}=1^{--}$ and $(0,1,2)^{++}$ charmoniumlike resonances below $4.1$ GeV, formulated in terms of ${c\overline{c}}$ and closed meson-meson channels, we calculate mass shifts and widths due to open meson-meson channels. This calculation does not involve any new free parameter, so comparison of our predictions with existing data provides a direct test of our approach. Further mass corrections are also estimated and good agreement with the measured masses comes out. As for the calculated widths, overall reasonable, they point out to the need of some refinement of our current bound state approximation for an accurate description of data. These results …
Standards. The building blocks of complexity
2021
Without standards, the world as we know it would not be possible. International and supra-cultural standards and norms have been a key factor in engineering, as well as in the development of industrial societies. Despite the obvious successes in electronic and mechanical design, other technological areas present difficulties for the application of standards. In the field of biotechnology and synthetic biology – which aims at studying living things from an engineering perspective – standards are desirable, but whether they can be widely adopted remains to be proved.
 This monograph reviews the sociological and scientific aspects of standardisation and delves into the more problematic fa…
Good to eat. Food and health at a time of information overload
2021
For most of the world's population, eating is no longer what it was just a few decades ago. The diversification and globalisation of the food supply, the industrialisation of food, and the abundance of information have simplified this everyday activity, but they have also made it more complex. Never before has it been so easy to eat well and to eat poorly. The proof is that obesity and overweight are no longer a problem exclusive to the richest, while nutritional deficiencies do not affect only the most impoverished. The new thing about our time is that both problems, over-nutrition and under-nutrition, coexist not only in countries and cities, but also within the same family and even throu…
A Paravermal Trans-Cerebellar Approach to the Posterior Fossa Tumor Causes Hypertrophic Olivary Degeneration by Dentate Nucleus Injury
2021
Background: In brain tumor surgery, injury to cerebellar connectivity pathways can induce a neurodegenerative disease called hypertrophic olivary degeneration (HOD), along with a disabling clinical syndrome. In children, cerebellar mutism syndrome (CMS) is another consequence of damage to cerebello&ndash
RAISE study protocol: a cross-sectional, multilevel, neurobiological study of resilience after individual stress exposure
2021
IntroductionThis paper describes the protocol for an ongoing project funded by the Royal Society, the Resilience After Individual Stress Exposure (RAISE) study; which aims to examine the factors and mechanisms that facilitate resilient functioning after childhood adversity (CA).Methods and analysisWe aim to recruit up to 200 participants. We will use dimension reduction techniques (principal component analysis) on standard-normally transformed individual parameters of mental health, social functioning and CA to calculate a composite measure of adaptive (ie, ‘resilient’) psychosocial functioning. To examine the neuroimmune responses to stress and their relationship with the brain and social …
Exploring the immersive journalism landscape
2021
Current drivers of 360-degree journalism have been mostly curious about the new medium, its possibilities, and are exploring business opportunities. The early adoption of such technology is often a matter of brand-building – that is, news organizations experimenting with virtual reality (VR) want to demonstrate that their digital strategies are forward-thinking (Watson 2017). After interviewing representatives from leading US newspapers, Bosworth and Sarah (2019, 226) also conclude, “among major media companies that failing to experiment in immersive and experimental stories will mean losing a race”. peerReviewed
Lepton-flavour violation in hadronic tau decays and μ-τ conversion in nuclei
2021
Within the Standard Model Effective Field Theory framework, with operators up to dimension 6, we perform a model-independent analysis of the lepton-flavour-violating processes involving tau leptons. Namely, we study hadronic tau decays and $\ell$--$\tau$ conversion in nuclei, with $\ell = e,\mu$. Based on available experimental limits, we establish constraints on the Wilson coefficients of the operators contributing to these processes. Our work paves the way to extract the related information from Belle II and foreseen future experiments.
Off-Modern Hybridity in TV Theatre: Theatrical, Cinematic and Media Temporalities in Rupert Goold’s Macbeth (BBC - Illuminations Media, 2010)
2021
Rupert Goold’s screen production of Macbeth – firstly, staged in 2007 and, later, filmed in 2010 – has been studied as an example of the stage-to-screen hybrid corpus of Shakespearean audio-visual adaptations. Thus, much of the critical emphasis on the production has been placed on its filmic qualities. Particularly, the genre film conventions deployed across the film has summoned the attention of Shakespeare on screen scholars and it has been the creators’ intentions to precisely point at Goold’s filmic intertextual repertoire. Given the recent increasing attention to the multiple media and languages employed in stage-to-screen hybrid Shakespearean adaptations and other exchanges between t…
Forecasting future trajectories for immersive journalism
2021
In this book we have critically explored the emerging practices of immersive journalism. In the news business, experimenting with new forms of storytelling has become the new normal. After spending a decade to get familiar with simple virtual reality tools, however, the future of immersive journalism is still considered uncertain. Immersive storytelling appears to become more concentrated on special events and locations. Journalistic virtual reality skills are increasingly crafted away from the newsrooms by small and specialized subcontractors. Sponsoring VR by the big tech companies tends to diminish in parallel with a growing move towards augmented reality investments. peerReviewed
Augmented reality as news
2021
If you are building complex, expensive VR today for the limited number of people, who get VR headsets, and [are] willing to scratch up on their heads to have the experience, experimentation is great, nice, but […] I think augmented reality is actually more interesting and has more potential for news. peerReviewed
Socio-cultural lock-ins and the difficulty of sustainability transition in fertilization : response to Struckman
2021
This commentary discusses the socio-cultural context of farming and proposes ways to break related lock-ins in the context of sustainability transition research. To be able to change farming practices and design policies to promote the changes, it is essential to understand what actually needs to change. Do we need to change the ways farmers think, the ways that food markets operate, the requirements of plant varieties or the requirements related to protecting water quality? In a complex situation the needed change emerges from the intertwinement of many different issues, which simultaneously work to create the locked-in situation. A focus on people and their practices provides a good start…
Recommendations for ophthalmologic practice during the easing of COVID‐19 control measures
2021
Abstract In the context of the COVID‐19 pandemic, this paper provides recommendations for medical eye care during the easing of control measures after lockdown. The guidelines presented are based on a literature review and consensus among all Spanish Ophthalmology Societies regarding protection measures recommended for the ophthalmologic care of patients with or without confirmed COVID‐19 in outpatient, inpatient, emergency and surgery settings. We recommend that all measures be adapted to the circumstances and availability of personal protective equipment at each centre and also highlight the need to periodically update recommendations as we may need to readopt more restrictive measures de…
Odorants of Capsicum spp. Dried Fruits as Candidate Attractants for Lasioderma serricorne F. (Coleoptera: Anobiidae)
2021
The cigarette beetle, Lasioderma serricorne F. (Coleoptera: Anobiidae) is an important food storage pest affecting the tobacco industry and is increasingly impacting museums and herbaria. Monitoring methods make use of pheromone traps which can be implemented using chili fruit powder. The objective of this study was to assess the response of L. serricorne to the volatile organic compounds (VOCs) from different chili powders in order to identify the main semiochemicals involved in this attraction. Volatiles emitted by Capsicum annuum, C. frutescens, and C. chinense dried fruit powders were tested in an olfactometer and collected and analyzed using SPME and GC-MS. Results indicated that C. an…