showing 36 of ~574560 from 574555 documents
Measurements of Differential Cross Sections of Inclusive $\pi^0$ and $K^0_S$ Production in $e^{+}e^{-}$ Annihilation at Energies from 2.2324 to 3.671…
2022
Based on electron positron collision data collected with the BESIII detector operating at the BEPCII storage rings, the differential cross sections of inclusive $\pi^0$ and $K^0_S$ production as a function of hadron momentum, normalized by the total cross section of the $e^{+}e^{-} \to$ hadrons process, are measured at six center-of-mass energies from 2.2324 to 3.6710 GeV. Our results with a relative hadron energy coverage from 0.1 to 0.9 significantly deviate from several theoretical calculations based on existing fragmentation functions, especially at lower energies.
Correction to: Female-driven social entrepreneurship in service business
2022
The United Nations has stated that to meet the 17 Sustainable Development Goals of the 2030 Agenda, analysis of the development and impact of women entrepreneurship is needed. Based on data from the Web of Science, an initial analysis of research on both women entrepreneurship and social entrepreneurship was performed. Although the frst published article date back to 2004, it was not until 2014 when scholars began to study women social entrepreneurship more systematically. This special issue covers these two areas in conjunction, with an added emphasis on service business.
Purity rules in Pentecostal Uganda. Towards an analysis of relational rulework
2022
Rules concerning romantic relationships and sex—what we term ‘purity rules’—are central to Pentecostalism in Uganda. In public church arenas, the born-again variant of the rules laid down during Uganda’s ‘ABC’ response to HIV/AIDS — ‘abstain till marriage and be faithful once you marry’—are presented as clear and non-negotiable. Yet in church members’ lives, and in their conversations with each other or in small church groups, space is often created for interpretation and deliberation about the officially strict rules. In this article, we use ethnographic material from fieldwork in urban Pentecostal churches in Uganda to describe how rules work on people, and people work on rules. We descr…
“They make a diference” : a qualitative study of providers’ experiences of peer support in outpatient clinics for people living with HIV
2022
Abstract Background Although the life expectancy of people living with HIV has increased, they are still often disconnected from society through stigma and discrimination. Peer support has been found to increase social support. Given the limited research on peer support from the providers’ perspective, this study explored how peer supporters experience their roles and contributions in outpatient clinics (OPCs). Additionally, healthcare professionals’ perceptions of working with peer supporters in OPCs were examined. Methods This qualitative study included purposively selected peer supporters (n = 10) and healthcare professionals (n = 5) from five OPCs in Norway in 2020. In-depth interviews…
Evaluation of the Oral Microcirculation in Patients Undergoing Anti COVID-19 Vaccination: A Preliminary Study
2022
Videocapillaroscopy allows the study of both the morphological and architectural structure of the microcirculation and its hemodynamic conditions; these parameters are directly involved in autoimmune and/or inflammatory pathologies. The purpose of this research, based on capillaroscopy, is to establish whether a patient who receives an anti-COVID 19 vaccine has any changes in their oral microcirculation. A complete capillaroscopic mapping of the oral cavity of the subjects examined was made; the investigated mucosa sites were the following: cheek, labial, chewing-gingival and back of the tongue. This study showed an increase in capillary density from the comparison between the mean labial c…
Effects of Age and Playing Tactics on the Individual Tactical Behavior in U10 and U12 Elite Spanish Soccer Players
2022
The aim of this paper was to explore the effects of age and playing tactics on the individual tactical behavior and performance in young soccer players. A total of 1247 individual possessions during 16 knockout matches from LaLiga Promises U12 tournament (n = 621) and LaLiga U10 Iscar Cup (n = 626) were analyzed by observational methodology. Multilevel and multivariate logistic regression models were created to explain the interdependent effects of age category and playing tactics on the individual tactical behavior and performance. Youth players performed most of their actions against defensive pressure (72.5%), during offensive support (91.3%) and receiving the ball facing forward (62.6%)…
A novel NF1 mutation in a pediatric patient with renal artery aneurysm
2022
Abstract Background Neurofibromatosis type 1 (NF1) is a neurocutaneous syndrome, due to heterozygous pathogenic variants in NF1 gene. The main clinical manifestations are multiple café au lait spots, axillary and inguinal freckling, cutaneous and plexiform neurofibromas, optic glioma, Lisch nodules and osseous lesions, such as sphenoid and tibial dysplasia. Vasculopathy is another feature of NF1; it consists of stenosis, aneurysms, and arteriovenous malformations, frequently involving renal arteries. Case presentation We report on a 9-year-old girl with a novel mutation in NF1 gene and renal artery aneurysm, treated by coil embolization and complicated with hypertension. Conclusion Vasculop…
Flashing lights affect the photophysiology and expression of carotenoid and lipid synthesis genes in Nannochloropsis gaditana
2022
Nannochloropsis gaditana is a promising microalga for biotechnology. One of the strategies to stimulate its full potential in metabolite production is exposure to flashing lights. Here, we report how N. gaditana adapts to different flashing light regimes (5, 50, and 500 Hz) by changing its cellular physiology and the relative expression of genes related to critical cellular functions. We analyzed the differential mRNA abundance of genes related to photosynthesis, nitrogen assimilation and biosynthesis of chlorophyll, carotenoids, lipids, fatty acids and starch. Analysis of photosynthetic efficiency and high mRNA abundance of photoprotection genes supported the inference that excess excitati…
Cyanobacteria and their metabolites in mono- and polidominant shallow eutrophic temperate lakes
2022
Monodominant (one species dominates) or polidominant (multiple species dominate) cyanobacterial blooms are pronounced in productive freshwater ecosystems and pose a potential threat to the biota due to the synthesis of toxins. Seasonal changes in cyanobacteria species and cyanometabolites composition were studied in two shallow temperate eutrophic lakes. Data on cyanobacteria biomass and diversity of dominant species in the lakes were combined with chemical and molecular analyses of fifteen potentially toxin-producing cyanobacteria species (248 isolates from the lakes). Anatoxin-a, saxitoxin, microcystins and other non-ribosomal peptides formed the diverse profiles in monodominant (Planktot…
Prediction of Airport Pavement Moduli by Machine Learning Methodology Using Non-destructive Field Testing Data Augmentation
2022
For the purpose of the Airport Pavement Management System (APMS), in order to optimize the maintenance strategies, it is fundamental monitoring the pavement conditions’ deterioration with time. In this way, the most damaged areas can be detected and intervention can be prioritized. The conventional approach consists in performing non-destructive tests by means of a Heavy Weight Deflectometer (HWD). This equipment allows the measurement of the pavement deflections induced by a defined impact load. This is a quite expensive and time-consuming procedure, therefore, the points to be investigated are usually limited to the center points of a very large mesh grid. Starting from the measured defle…
Optimal Control of the Lotka-Volterra Equations with Applications
2022
In this article, the Lotka-Volterra model is analyzed to reduce the infection of a complex microbiote. The problem is set as an optimal control problem, where controls are associated to antibiotic or probiotic agents, or transplantations and bactericides. Candidates as minimizers are selected using the Maximum Principle and the closed loop optimal solution is discussed. In particular a 2d-model is constructed with 4 parameters to compute the optimal synthesis using homotopies on the parameters.
Modulation of Human Motor Cortical Excitability and Plasticity by Opuntia Ficus Indica Fruit Consumption: Evidence from a Preliminary Study through N…
2022
Indicaxanthin (IX) from Opuntia Ficus Indica (OFI) has been shown to exert numerous biological effects both in vitro and in vivo, such as antioxidant, anti-inflammatory, neuro-modulatory activity in rodent models. Our goal was to investigate the eventual neuro-active role of orally assumed fruits containing high levels of IX at nutritionally-relevant amounts in healthy subjects, exploring cortical excitability and plasticity in the human motor cortex (M1). To this purpose, we applied paired-pulse transcranial magnetic stimulation and anodal transcranial direct current stimulation (a-tDCS) in basal conditions and followed the consumption of yellow cactus pear fruits containing IX or white ca…
Controlling Floquet states on ultrashort time scales
2022
AbstractThe advent of ultrafast laser science offers the unique opportunity to combine Floquet engineering with extreme time resolution, further pushing the optical control of matter into the petahertz domain. However, what is the shortest driving pulse for which Floquet states can be realised remains an unsolved matter, thus limiting the application of Floquet theory to pulses composed by many optical cycles. Here we ionized Ne atoms with few-femtosecond pulses of selected time duration and show that a Floquet state can be observed already with a driving field that lasts for only 10 cycles. For shorter pulses, down to 2 cycles, the finite lifetime of the driven state can still be explained…
Dual Stimuli-Responsive Polysaccharide Hydrogels Manufactured by Radiation Technique
2022
Featured Application Stimuli-responsive hydrogels encompassing biobased polymers are anticipated for utilization in various fields, starting from drug delivery systems through temporal actuators and water reservoirs to biodegradable microelements and nutrient delivery depots. This paper describes the results of the radiation-induced crosslinking of polysaccharides modified with hydroxypropyl and carboxymethyl functional groups, hydroxypropylcellulose (HPC) and carboxymethylcellulose (CMC), respectively, without and with poly(ethylene glycol) diacrylate (PEGDA) as a crosslinking agent, to obtain dual stimuli-responsive hydrogels. The gels were characterized in terms of water uptake and gel f…
Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel.
2022
In vitro antiproliferative assays still represent one of the most important tools in the anticancer drug discovery field, especially to gain insights into the mechanisms of action of anticancer small molecules. The NCI-DTP (National Cancer Institute Developmental Therapeutics Program) undoubtedly represents the most famous project aimed at rapidly testing thousands of compounds against multiple tumor cell lines (NCI60). The large amount of biological data stored in the National Cancer Institute (NCI) database and many other databases has led researchers in the fields of computational biology and medicinal chemistry to develop tools to predict the anticancer properties of new agents in advan…
Quantifying Irrigated Winter Wheat LAI in Argentina Using Multiple Sentinel-1 Incidence Angles
2022
Synthetic aperture radar (SAR) data provides an appealing opportunity for all-weather day or night Earth surface monitoring. The European constellation Sentinel-1 (S1) consisting of S1-A and S1-B satellites offers a suitable revisit time and spatial resolution for the observation of croplands from space. The C-band radar backscatter is sensitive to vegetation structure changes and phenology as well as soil moisture and roughness. It also varies depending on the local incidence angle (LIA) of the SAR acquisition’s geometry. The LIA backscatter dependency could therefore be exploited to improve the retrieval of the crop biophysical variables. The availability of S1 radar time-series data at d…
Self-cleaning ZnO/ITO/PET Bending Sensors
2022
The design of multifunctional materials is of pivotal importance for developing wearable biosensors. In particular, the advancement in self-cleaning materials suitable for bending sensors, i.e. devices able to track human body movements for healthcare monitoring [1], has raised much interest in recent pandemic times. Such technology can be facilitated by leveraging piezo-photocatalytic cleaning effects under visible light [2]. Herein, we show a new class of ZnO-based nanosheets (NSs) synthesized in aqueous solution (85 °C, 24 hours) onto seeded or seedless ITO/PET surfaces that couple sensing to photocatalysis. UV-vis and FT-IR spectroscopies show the typical absorption peaks of ZnO. A nano…
COVID-19 Vaccination in Migrants and Refugees: Lessons Learnt and Good Practices.
2022
The COVID-19 pandemic has exacerbated inequalities between low- and high-income countries. Within the latter, a greater impact is seen in the poorest and most vulnerable people, including refugees, asylum seekers, and migrants. They all may experience poor access to quality healthcare or have suboptimal health-seeking behavior, distrust of governments, or fear of detention and deportation if seeking healthcare. Some refugees and migrants may face multiple barriers to vaccination and access to health systems that are relevant to the administration of COVID-19 vaccines, despite the growing inclusion of these populations in public health policies. Several good practices have emerged to ensure …
Resistance Is Useless! (And So Are Resilience and Reworking): Migrants in the Finnish Labour Market
2022
AbstractIn Finland, integration is discussed in terms of labour market success. Finding work tends to occur in the ‘secondary’ labour market as migrants have difficulty accessing the more secure jobs of the ‘primary’ labour market. This chapter draws on 11 qualitative biographical narratives of migrants and refugees, looking for turning points and epiphanies about their job-seeking experiences. We classify these as agentic acts of resilience, reworking, and resistance, borrowing from Cindi Katz’s framework. Interviewees exhibited resilience in revising downward their expectations of what sort of job they would accept and how their career would develop. ‘Reworking’ was also often attempted, …
Role of Chemerin in Cardiovascular Diseases.
2022
(1) Background: Obesity is closely connected to the pathophysiology of cardiovascular diseases (CVDs). Excess fat accumulation is associated with metabolic malfunctions that disrupt cardiovascular homeostasis by activating inflammatory processes that recruit immune cells to the site of injury and reduce nitric oxide levels, resulting in increased blood pressure, endothelial cell migration, proliferation, and apoptosis. Adipose tissue produces adipokines, such as chemerin, that may alter immune responses, lipid metabolism, vascular homeostasis, and angiogenesis. (2) Methods: We performed PubMed and MEDLINE searches for articles with English abstracts published between 1997 (when the first re…
Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures
2022
The clinical relevance of nozzle-like strictures in upper parts of the internal jugular veins remains unclear. This study was aimed at understanding flow disturbances caused by such stenoses. Computational fluid dynamics software, COMSOL Multiphysics, was used. Two-dimensional computational domain involved stenosis at the beginning of modeled veins, and a flexible valve downstream. The material of the venous valve was considered to be hyperelastic. In the vein models with symmetric 2-leaflets valve without upstream stenosis or with minor 30% stenosis, the flow was undisturbed. In the case of major 60% and 75% upstream stenosis, centerline velocity was positioned asymmetrically, and areas of…
Utilizing Informal Formative Assessment and Dialogicity During Reflections on Educational Dialogue in Mathematics
2022
In this study, educational dialogue is explored through informal formative assessment and dialogicity. We enhance the understanding of informal formative assessment and dialogicity by considering their relationship. Even though the interconnection of informal formative assessment and dialogicity is acknowledged, it has not been explicitly examined in research on educational dialogue. The data consists of video-stimulated joint reflections between mathematics student teachers and a teacher educator. The reflections were part of a teacher education program integrated in a mathematics pedagogic course. Conversational analysis was conducted to detect interactional patterns and indicators that e…
A curious case of pancytopenia and fever in a patient with Erdheim–Chester disease
2022
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Galactosylated Polymer/Gold Nanorods Nanocomposites for Sustained and Pulsed Chemo-Photothermal Treatments of Hepatocarcinoma
2022
In this paper, we propose a rational design of a hybrid nanosystem capable of locally delivering a high amount of hydrophobic anticancer drugs (sorafenib or lenvatinib) and heat (hyperthermia) in a remote-controlled manner. We combined in a unique nanosystem the excellent NIR photothermal conversion of gold nanorods (AuNRs) with the ability of a specially designed galactosylated amphiphilic graft copolymer (PHEA-g-BIB-pButMA-g-PEG-GAL) able to recognize hepatic cells overexpressing the asialoglycoprotein receptor (ASGPR) on their membranes, thus giving rise to a smart composite nanosystem for the NIR-triggered chemo-phototherapy of hepatocarcinoma. In order to allow the internalization of A…
Dynamic Responsive Inguinal Scaffold Activates Myogenic Growth Factors Finalizing the Regeneration of the Herniated Groin
2022
Background: Postoperative chronic pain caused by fixation and/or fibrotic incorporation of hernia meshes are the main concerns in inguinal herniorrhaphy. As inguinal hernia is a degenerative disease, logically the treatment should aim at stopping degeneration and activating regeneration. Unfortunately, in conventional prosthetic herniorrhaphy no relationship exists between pathogenesis and treatment. To overcome these incongruences, a 3D dynamic responsive multilamellar scaffold has been developed for fixation-free inguinal hernia repair. Made of polypropylene like conventional flat meshes, the dynamic behavior of the scaffold allows for the regeneration of all typical inguinal components: …
A centuries-long enslavement? Gender and Islam in the Hispanic Enlightenment: an exploratory approach
2022
This article explores the role of gender in the construction of images of Islam in the Hispanic Enlightenment. Although Spanish Arabism has been largely neglected in international historiography, research has proved that Spanish erudites since the 16th century had an important role in the study of the Arabic language and sources; also, interest in the Islamic world was popularized via fictional works and coverage in newspapers and journals. Spain is a distinctive and particularly interesting case within European Orientalism because Islam was part of its history and cultural legacy and a close neighbour in the north of Africa, but also because orientalization of the country by European trave…
Machine learning and ontology in eCoaching for personalized activity level monitoring and recommendation generation.
2022
AbstractLeading a sedentary lifestyle may cause numerous health problems. Therefore, passive lifestyle changes should be given priority to avoid severe long-term damage. Automatic health coaching system may help people manage a healthy lifestyle with continuous health state monitoring and personalized recommendation generation with machine learning (ML). This study proposes a semantic ontology model to annotate the ML-prediction outcomes and personal preferences to conceptualize personalized recommendation generation with a hybrid approach. We use a transfer learning approach to improve ML model training and its performance, and an incremental learning approach to handle daily growing data …
Structural analyses in the study of behavior : From rodents to non-human primates
2022
Ajuts: J-BL's research was funded by Natural Sciences and Engineering Research Council of Canada (NSERC, Discovery Grant #: 2015-06034 to J-BL). MC, SA, and GC's research was funded by a grant from the University of Palermo, Italy. The term " structure " indicates a set of components that, in relation to each other, shape an organic complex. Such a complex takes on essential connotations of functionally unitary entity resulting from the mutual relationships of its constituent elements. In a broader sense, we can use the word " structure " to define the set of relationships among the elements of an emergent system that is not determined by the mere algebraic sum of these elements, but by the…
Creatine consumption and liver disease manifestations in individuals aged 12 years and over
2022
Despite the overwhelming safety evidence concerning creatine intake in various settings, there is still incomplete information whether dietary creatine affects liver health at the population level. The main aim of this cross-sectional population-based study was to evaluate the association between creatine intake through regular diet and liver disease manifestations, including liver fibrosis and hepatic steatosis, among individuals aged 12 years and over, using open-source data from the 2017–2018 U.S. National Health and Nutrition Examination Survey (NHANES). A total of 9254 male and female participants of all ages were included in the 2017–2018 NHANES round. We extracted data from the total…
Molecular quantum interface for storing and manipulating ultrashort optical vortex
2022
Light beams carrying orbital angular momentum (OAM) have become over the past few years a subject of widespread interest with unprecedented applications in various fields such as optical communication, super-resolution imaging, optical tweezers, or quantum processing. We demonstrate in the present work that gas-phase molecules can be used as a quantum interface to store an OAM carried by an ultrashort laser pulse. The interplay between spin angular momentum and OAM is exploited to encode the spatial phase information of light beams into rotational coherences of molecules. The embedded spatial structure is restored on-demand with a reading beam by taking advantage of field-free molecular ali…
“I look with deep gratitude and admiration ...” – praising and complimenting in papal speeches
2022
Abstract Recently, communicating admiration and appreciation in public discourse has become a subject of study since these acts play a very important role in shaping positive social relations not only on a micro scale, but also on a macro one. My goal in this study is to understand how public officials implement their intention to please addressees in an international arena, in contacts between different religious and national communities. In order to do this, 120 papal speeches delivered to representatives of different churches, religions and societies were analysed, identifying individual topics, functions and patterns of these speech acts, as well as their dependence on such parameters a…
La fabrique discursive d’un consensus: retour sur la couverture médiatique de la campagne de vaccination COVID-19 dans quatre grands médias français
2022
International audience
Gum health and quality of life-subjective experiences from across the gum health-disease continuum in adults
2022
Abstract Background There has been a lack of qualitative work investigating the effects of the wide range of gum-related symptoms, and the perceived everyday impacts associated with these including on quality of life. While periodontal disease has been shown to have significant effects on quality of life, fewer studies have researched the perceived impacts of gingivitis and symptoms from across the entire gum health-disease continuum, despite evidence that these can also negatively affect quality of life. The aim of this study was to investigate perceived everyday impacts and explore the subjective experiences of adults with a variety of symptoms from across the self-reported gum health-dis…
New tricyclic systems as photosensitizers towards triple negative breast cancer cells.
2022
AbstractNineteen pyrrolo[1,2-h][1,7]naphthyridinones and pyrido[2,3-c]pyrrolo[1,2-a]azepinones were synthesized as new tricyclic systems in which the pyridine ring is annelated to the 6,7-dihydroindolizin-8(5H)-one and 5,6,7,8-tetrahydro-9H-pyrrole[1,2-a]azepine-9-one moieties to obtain potential photosensitizing agents. They were tested for their photoantiproliferative activity on a triple-negative breast cancer cell line, MDA-MB-231, in the dark and under UVA light (2.0 J/cm2). We demonstrated that their toxicity, only when exposed to light, was primarily due to the generation of reactive oxygen species while their photodegradation products were not responsible for their activity. The mos…
Professional social media-enabled productivity : a five-wave longitudinal study on the role of professional social media invasion, work engagement an…
2022
PurposeSocial media platforms are increasingly used at work to facilitate work-related activities and can either challenge or make people feel more productive at jobs. This study drew from technostress and employee well-being literature and analyzed longitudinal effects of professional social media (PSM) invasion, work engagement and work exhaustion on PSM-enabled productivity.Design/methodology/approachNationally representative five-wave survey data of Finnish employees were analyzed with hybrid multilevel linear regression analysis. Outcome measure was PSM-enabled productivity and the predictors included PSM invasion, work exhaustion and work engagement. Age, gender, education, occupation…
Vanadium Modulates Proteolytic Activities and MMP-14-Like Levels during Paracentrotus lividus Embryogenesis
2022
The increasing industrial use of vanadium (V), as well as its recent medical use in various pathologies has intensified its environmental release, making it an emerging pollutant. The sea urchin embryo has long been used to study the effects induced by metals, including V. In this study we used an integrated approach that correlates the biological effects on embryo development with proteolytic activities of gelatinases that could better reflect any metal-induced imbalances. V-exposure caused morphological/morphometric aberrations, mainly concerning the correct distribution of embryonic cells, the development of the skeleton, and the embryo volume. Moreover, V induced a concentration change …