showing 36 of ~574560 from 574555 documents
Pathogenic correlation between mosaic variegated aneuploidy 1 (MVA1) and a novel BUB1B variant: a reappraisal of a severe syndrome.
2022
Funder: Università degli Studi di Catania
Temporally stable beta sensorimotor oscillations and cortico–muscular coupling underlie force steadiness
2022
Funding Information: Data and code are available on the Open Science Framework (OSF) at the following link: https://osf.io/4rmex/?view_only=7d17c2334ace4a0d83087bddf2a64a68. Scott Mongold, Thomas Legrand, and Mathieu Bourguignon were supported by the Fonds de la Recherche Scientifique (F.R.S.-FNRS, Brussels, Belgium; grant MIS F.4504.21). Harri Piitulainen was supported by the Academy of Finland (grants 266133, 296240, 326988, 327288 and 311877) including “Brain changes across the life-span” profiling funding to University of Jyväskylä. We thank Helge Kainulainen and Ronny Schreiber at Aalto NeuroImaging for providing technical help and the force sensor system for the study. We thank Riitta…
Measuring technical efficiency of Greek red suckler cow breed's farms in Central Macedonia region using a data envelopment analysis model
2022
This study aims to estimate the technical efficiency (TE) of a randomly selected sample of red Greek suckler cow breed farms in the area of Central Macedonia and identify the most technically efficient characteristics of cow-calf operations. Moreover, this work wants to verify the impact of local and European policies in support of the sector on the estimated efficiency. The research investigates the technical efficiency of 64 suckler cow farms by using the data envelopment analysis (DEA) method. Findings reveal that the most efficient farms were larger, with higher gross revenue, and higher cost of fixed capital than non-efficient farms. In addition, the cost of variable capital, which dir…
Evaluation of crack-closure by second harmonic thermoelastic stress analysis
2022
The work illustrates a new experimental approach to evaluate crack-closure in samples undergoing Fatigue Crack-Growing. Crack-closure leaves a peculiar signature on both amplitude and phase of the harmonic of the temperature signal at twice the loading frequency (Second Harmonic), due to the periodic nature of the internal elastic compression stresses. Thermoelastic Stress Analysis (TSA) is successfully applied to reveal such signatures on Single-Edge-Notched steel samples. A methodology is also proposed to evaluate the Crack-Opening-Load from temperature data. The work finally explores the influence of crack-closure on crack-tip identification and on the evaluation of the Stress Intensity …
Nutrient recovery from wastewater treatment by ultrafiltration membrane for water reuse in view of a circular economy perspective
2022
The study aims to recover nitrogen from wastewater by employing ultrafiltration membrane in water reuse for agriculture purpose. To such aim, a new reclaimed water quality index (RWQI) is proposed and applied including an innovative protocol for its assessment. Specifically, the influence of filtration and backwashing times for an ultrafiltration system aimed to nutrient recovery has been analyzed. The final goal was to pin down the trade-off between operation costs and effluent quality. Results show that backwashing time play a crucial role in reducing the operation costs; indeed, low values (i.e., 0.5 min) lead to an increase in the number of required chemical cleanings and consequently o…
Violation-mitigation-based method for PV hosting capacity quantification in low voltage grids
2022
Hosting capacity knowledge is of great importance for distribution utilities to assess the amount of PV capacity possible to accommodate without troubling the operation of the grid. In this paper, a novel method to quantify the hosting capacity of low voltage grids is presented. The method starts considering a state of fully exploited building rooftop solar potential. A downward process is proposed—from the starting state with expected violations on the grid operation to a state with no violations. In this process, the installed PV capacity is progressively reduced. The reductions are made sequentially and selectively aiming to mitigate specific violations: nodes overvoltage, lines overcurr…
Interactive decision support and trade-off analysis for sustainable forest landscape planning under deep uncertainty
2022
Sustainable environmental management often involves long-term time horizons and multiple conflicting objectives and, by nature, is affected by different sources of uncertainty. Many sources of uncertainty, such as climate change or government policies, cannot be addressed using probabilistic models, and, therefore, they can be seen to contain deep uncertainty. In this setting, the variety of possible future states is represented as a set of scenarios lacking any information about the likelihood of occurring. Integrating deep uncertainty into multiobjective decision support increases complexity, calling for the elaboration of appropriate methods and tools. This paper proposes a novel intera…
Sealing the Cranial Base Access After Endonasal Endoscopic Approach: Reabsorption Rate of Fat Graft in the "3FTechnique".
2022
Daily moods, health routines and recovery among employees working in the retail and services sector : A diary study
2022
This study examined the quality and fluctuation of daily moods as well as health routines and means of recovery from work strain among employees (n = 38) working nonstandard, often unpredictable schedules in the retail and services sector in Finland. Data were collected via a background questionnaire and a one-week mobile diary. The results indicated that the daily moods of employees were relatively positive but varied greatly from day to day. Hectic working days, unpredictable changes in work schedules, and compounded responsibilities at home and work were reported as causes of daily strain stemming from work. In contrast, more sleep and exercise were positively associated with daily mood …
PNRR, lavoro pubblico e dintorni
2022
La legislazione di attuazione del PNRR contiene misure sul reclutamento e sulla progressione di carriera del personale pubblico, nonche´ sulla dirigenza, dirette allo scopo del rafforzamento della capacita` amministrativa delle istituzioni pubbliche. Esse presentano alcune luci e molte ombre su cui vale la pena soffermarsi. Peraltro, i grandi processi di trasformazione e transizione in atto reclamano un forte coinvolgimento delle parti sociali per garantire una loro gestione e una (auspicabile) crescita economica socialmente eque e sostenibili.
Esporre gli archivi del Novecento. Anton Giulio Bragaglia, l'archivio di un visionario
2022
Il contesto della storia: qualche riflessione a partire da una mostra romana sui materiali dell’ archivio di Anton Giulio Bragaglia, fotografo, pubblicista, regista cinematografico e teatrale, drammaturgo attivo a Roma sin dagli anni dieci del secolo scorso. Autore d’avanguardia, Bragaglia si è occupato del teatro classico e del Rinascimento teorizzando, al tempo stesso, nuovi linguaggi scenici. Intellettuale poliedrico ha praticato quell’interdisciplinarietà e multimodalità, propria di molta ricerca visuale degli ultimi decenni, coniugando l’attenzione per la memoria dell’antico e per la tradizione della cultura italiana, con le istanze più aggiornate del dibattito a lui contemporaneo. Pro…
DEVELOPING AN INTEGRATED FRAMEWORK FOR ANALYZING WAYS OF REASONING IN MATHEMATICS
2022
Mathematics education literature involves studies that sought a way of investigating the mode of reasoning in mathematics textbooks because textbooks are the main resource for teachers in planning their mathematics lessons. In this vein, this study aimed to analyze the ways of reasoning in mathematics textbooks that are currently used in five countries: Slovakia, Czech Republic, Italy, Norway, and Turkiye, as a part of a Horizon 2020 Project. We initially started with a framework that aimed to examine the effect of teachers’ participation in the lesson study on the improvement of students’ mathematical reasoning (Project LESSAM). However, as the textbook analysis of different countries proc…
Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells
2022
Burn wound healing is a very intricate and complex process that conventionally includes three interrelated and overlapping stages of hemostasis/inflammation, proliferation and remodeling. This review aims to explore the molecular interactions of NGF with the most prominent cell types in the skin and their respective secretory products during wound healing, particularly burn wound healing. Different types of cells such as, nerve cells, endothelial cells, mast cells, macrophages, neutrophils, keratinocytes and fibroblasts all come into play through a plethora of cytokines and growth factors including nerve growth factor (NGF). NGF is a pleiotropic molecule that exerts its effects on all the a…
Le difficoltà probatorie per superare il ragionevole dubbio nei processi di criminalità organizzata
2022
Analisi diacronica delle problematiche probatorie più rilevanti nei procedimenti per "fatti di mafia" con proiezioni sul convincimento del giudice e sul contraddittorio probatorio. Il preteso ruolo normante della giurisprudenza viene posto a raffronto con frizioni dogmatiche e ricadute operative dimostrando la fragilità degli accertamenti in tema di indicatori della partecipazione alla associazione, della base indiziaria e della "messa a disposizione".
A smartphone-based innovative approach to discriminate red pigments in roman frescoes mock-ups
2022
The characterization of red pigments in frescoes wall paintings has been of great interest for researchers to better understand raw material procurement dynamics, pigment receipts, stylistic evolution and to assess their conservation state. In this study a non-destructive colorimetric approach implementing a smartphone-based method was developed in order to be able to distinguish between three pigments made from minium, haematite and cinnabar minerals, and also mixed pigments, preparing frescoes mock-ups following the roman receipt described by Vitruvius. Portable FT-IR, Raman spectroscopy, portable XRF and visible reflectance spectra analyses were carried out as reference methods for smart…
Tra due poli: fonti e caratteri giuridico-istituzionali dei rapporti tra Papato e vescovati siciliani in età normanna (secc. XI-XII)
2022
The aim of this work is to examine the sources relating to the legalinstitutional relations between the Papacy and the bishoprics of the island of Sicily, between the 11th and 12th centuries. The investigation aims to verify in what ways, and according to what forms, each pope directed his action to get in touch with the bishops in charge of the different ecclesiastical sees. On the other hand, it is also intended to examine whether the Sicilian bishops themselves attempted in some way to accredit their action towards the Apostolic See. The two poles evoked in the title – the Sicilian Monarchy and the Church of Rome – represent respectively the two highest authorities for the Churches of th…
Unveiling the disc structure in ultraluminous X-ray source NGC 55 ULX-1
2022
Ultraluminous X-ray sources (ULXs) are the most extreme among X-ray binaries in which the compact object, a neutron star or a black hole, accretes matter from the companion star, and exceeds a luminosity of 1039 ergs−1 in the X-ray energy band alone. Despite two decades of studies, it is still not clear whether ULX spectral transitions are due to stochastic variability in the wind or variations in the accretion rate or in the source geometry. The compact object is also unknown for most ULXs. In order to place constraints on to such scenarios and on the structure of the accretion disc, we studied the temporal evolution of the spectral components of the variable source NGC 55 ULX-1. Using rec…
ALBERT O. HIRSCHMAN AT THE FEDERAL RESERVE, 1946–1952
2022
This essay introduces the work conducted by Albert O. Hirschman at the Federal Reserva Bank. His main areas of interest, on which he produce original research, were European postwar reconstruction and integration; country studies (Italy and France, particularly), alternative modes of economic development; the role of the US in assisting reconstruction and development.
Le evoluzioni dello sviluppo locale in Sicilia: i Sicani dalla SNAI all’integrazione con le politiche di sviluppo rurale
2022
La Strategia Nazionale Aree Interne (SNAI) è entrata in una nuova fase, in cui si prefigura la trasformazione da policy sperimentale a politica strutturale e, insieme ad altre strategie anche preesistenti concorre non senza criticità a ridefinire le traiettorie di sviluppo di queste parti del Paese. Gli sviluppi di quanto sta avvenendo sui Sicani in Sicilia sono indicativi delle interazioni tra SNAI ed altre strategie di settore, come la Strategia di Sviluppo Rurale, e indicano alcuni approcci di integrazione e di armonizzazione delle politiche attivate e delle azioni già in corso.
Tensions and Paradoxes of Scaling Up : A Critical Reflection on Physical Activity Promotion
2022
Background: Achieving system-level, sustainable ‘scale-up’ of interventions is the epitome of successful translation of evidence-based approaches in population health. In physical activity promotion, few evidence-based interventions reach implementation at scale or become embedded within systems for sustainable health impact. This is despite the vast published literature describing efficacy studies of small-scale physical activity interventions. Research into physical activity scale-up (through case-study analysis; evaluations of scale-up processes in implementation trials; and mapping the processes, strategies, and principles for scale-up) has identified barriers and facilitato…
Post-COVID syndrome, inflammation, and diabetes
2022
The raging COVID-19 pandemic is in its third year of global impact. The SARS CoV 2 virus has a high rate of spread, protean manifestations, and a high morbidity and mortality in individuals with predisposing risk factors. The pathophysiologic mechanisms involve a heightened systemic inflammatory state, cardiometabolic derangements, and varying degrees of glucose intolerance. The latter can be evident as significant hyperglycemia leading to new -onset diabetes or worsening of preexisting disease. Unfortunately, the clinical course beyond the acute phase of the illness may persist in the form of a variety of symptoms that together form the so-called "Long COVID" or "Post-COVID Syndrome". It i…
Chemical and biochemical responses to sub−lethal doses of mercury and cadmium in gilthead seabream (Sparus aurata)
2022
Specimens of Sparus aurata were exposed to sub-lethal concentrations of Hg and Cd for 25 days and the levels of both metals were investigated in organs and tissues. Bioaccumulation of Hg decreased as follow: gills > kidney > liver > skin > muscle, while the order of Cd bioaccumulation was: liver > kidney > gills > skin > muscle. Immediately after exposure, both metals showed the highest bioaccumulation in gills and skin indicating that these organs are reliable targets for biomonitoring studies after short term exposure. Metals introduction caused a significant time-dependent concentrations increase in kidney and liver, while in the muscle a significant in-crease of …
La battaglia di Himera nelle Storie di Erodoto e il sincronismo con Salamina
2022
The very short report of the battle of Himera given by Herodotus’ Histories seems to have the primary aim of supporting a widespread tradition among the inhabitants of Sicily (still circulating at the time when the historian lived) about the true reason preventing Gelon from siding with the Hellenic League against Persians: he was impelled to engage in the battle of Himera, which took place the very same day as the sea battle of Salamis. No celebratory intent emerges from the account of Gelon’s and Theron’s victory over the Carthaginians, since Herodotus wants to report all the versions known to him about the explanations given to Gelon’s refusal to join the Hellenic League; there is no roo…
Dynamic simulation of a 4th Generation District Heating network with the presence of prosumers
2022
District Heating Network is identified as a promising technology for the decarbonization of urban areas. Thanks to the surplus of heat available from distributed renewable energy plants, a typical heat consumer of the network could become an energy producer during the day (typically referred to as “prosumer”). Models for thermal grids developed during the years usually assumed a centralized heat production. The increasing presence of prosumers will require accurate dynamic modeling to monitor the changes induced in the thermohydraulic variables of the network. To fill this knowledge gap, this paper aims at developing a model of a thermal grid with prosumers in TRNSYS environment. The model …
Note psicocriminologiche. La mafia tra antropologia criminale e psichiatria
2022
Nella riflessione intorno all’oggetto “mafia” l’intreccio tra campi del sapere diversi è stato, e continua a essere, indispensabile. Le definizioni della mafia si sono infatti storicamente prodotte all’intersezione tra politica, società e diritto. Da quale prospettiva, dunque, antropologi e psichiatri hanno considerato il comportamento mafioso e l’appartenenza al sodalizio mafioso, specie in relazione alla dimensione associativa?Dall’età liberale al fascismo, la mafia è stata considerata alla stregua di una evidenza antropologica, determinata da ambiente e contesto, se non da “atavismo”? O invece è stata considerata una manifestazione criminale, punibile in quanto tale, e nei tribunali si è…
The Descent of Man by C.R. Darwin. A continuous debate since 1871
2022
On the Descent of Man by Charles Robert Darwin. A continuous debate since 1871
Affordable housing in western Europe. Forms, typologies and paradigms through a genealogical approach. 1852-2019
2022
The essay concerns housing as a major tool for urban regeneration and for experiment in architecture. Within this larger research scope, this paper aims to explore some issues linked to contemporary European processes of urban regeneration through housing in a genealogical approach. At first, will be evocated the initial European typological evolution of affordable housing, outlining the early development of the urban working-class housing estate in Paris, and London . The discussion of the two main paradigms elaborated at that foundational stage will focuses the appearance of the open block for mixed-use housing at the very end of the 19th century. Then, the article will shortly engage wit…
Challenges and opportunities for citrus wastewater management and valorisation: A review.
2022
Citrus wastewaters (CWWs) are by-products of the citrus fruit transformation process. Currently, more than 700 million of m³ of CWWs per year are produced worldwide. Until nowadays, the management of CWWs is based on a take-make-use-dispose model. Indeed, after being produced within a citrus processing industry, CWWs are subjected to treatment and then discharged into the environment. Now, the European Union is pushing towards a take-make-use-reuse management model, which suggests to provide for the minimization of residual pollutants simultaneously with their exploitation through a biorefinery concept. Indeed, the recovery of energy nutrients and other value-added products held by CWWs may…
Buone pratiche e strumenti di analisi per l’apprendimento, l’insegnamento e l’inclusione
2022
Il presente lavoro, nato in seno al progetto di ricerca “Best practices and tools of analysis in schools and community contexts: learning, teaching & inclusion”, avviato su fondi del Dipartimento SPPEFF dell’Università di Palermo, nel marzo 2019 e giunto alla sua seconda fase. La metodologia di ricerca utilizzata – perché ritenuta adeguata a perseguire le finalità fissate e a fornire una visione complessa ed articolata del fenomeno investigato – è stata quella del Mixed Method, con particolare riferimento all’Explanatory Design: Participant Selection Model di Creswell, Plano Clark, et al. (2003). L’«Explanatory Design is a two-phase mixed methods design. The overall purpose of this desi…
Positioning flexibly scheduled ECEC in the chain of childcare by parents working non-standard hours
2022
This study examined how Finnish parents working non-standard hours (N=18) positioned institutional flexibly scheduled early childhood education and care (ECEC) as a link in their chain of childcare. Interview data, analysed following the principles of discursive psychology, yielded three discourses on flexibly scheduled ECEC: the discourse of the child’s best interest, the discourse of the labour market, and the discourse of equality of opportunity for the child. Flexibly scheduled ECEC was positioned in these discourses either as the last resort option for childcare, a safe haven for the child, a societal service enabling parents to work during non-standard hours or as a place for children…
Optimal selection of touristic packages based on user preferences during sports mega-events
2022
Sport mega-events, such as the Soccer World Cup or Olympic Games, attract many visitors from all over the world. Most of these visitors are also interested in, besides attending the sports events, visiting the host nation and the neighboring countries. In this paper, we focus on the upcoming FIFA World Cup Qatar 2022. As per the schedule of the tournament, a national team can play 7 matches at most. Therefore, a supporter will have six short breaks (of three to five days) between consecutive matches in addition to two longer ones, immediately before and after the tournament, during which they can plan some touris- tic trips. We study the problem faced by a touristic trip provider who wants …
Prospezione speleoarcheologica della falesia «Piana di Sopra» a San Vito lo Capo (TP)
2022
The northern coast of Trapani is characteristed by a series of phenomena linked to Quaternary glaciations. These phenomena have modeled esplanades, terraces, cliffs, leaf grooves and caves of great natural beuaty. The extreme strip of the Peninsula of S. Vito lo Capo, the Piana di Sopra, is made up of parareciphal limestones with Orbitoline and Rudist from the Cretaceous. This area has a strong density of cavities of marine origin estimated at four cavities per kilometer. These cavities are an important anthropological testimonly to a continual human presence from deep prehistory onwards. A fundamental prerequisite for a study of the prehistory of an area is its geomorphologic description w…
When the Past Makes Saints: The Knights of Malta from Sinners to Martyrs in "Il glorioso trionfo della sacrosanta religion militare di S. Giovanni Gi…
2022
After the fall of Rhodes (1522), the Order of St. John needed to recover its reputation as militia Christi and to redraft its chivalrous ideals within the context of the Catholic Renewal. However, this so-called Religion met this challenge partially and late, although it represented its glorious past as a gallery of saints and martyrs, even if they were not always officially recognised by the Church. This past, since its origin in the Holy Land, casted a shadow of sanctity into the present, confirming this Religion as being semper eadem. Such a representation is found in the book Il glorioso trionfo della sacrosanta religion militare di S. Giovanni Gierosolimitano, published in 1619 in Ital…
Integration of lot sizing and safety strategy placement using interactive multiobjective optimization
2022
We address challenges of unpredicted demand and propose a multiobjective optimization model to integrate a lot sizing problem with safety strategy placement and optimize conflicting objectives simultaneously. The novel model is devoted to a single-item multi-period problem in periodic review policy. As a safety strategy, we use the traditional safety stock concept and a novel concept of safety order time, which uses a time period to determine the additional stock to handle demand uncertainty. The proposed model has four objective functions: purchasing and ordering cost, holding cost, cycle service level and inventory turnover. We bridge the gap between theory and a real industrial problem a…
Benign liver lesions 2022: Guideline for clinical practice of Associazione Italiana Studio del Fegato (AISF), Società Italiana di Radiologia Medica e…
2022
Benign liver lesions are increasingly diagnosed in daily clinical practice due to the growing use of imaging techniques for the study of the abdomen in patients who have non-specific symptoms and do not have an increased risk of hepatic malignancy. They include simple or parasitic cysts and solid benign tumors which differ widely in terms of prevalence, clinical relevance, symptoms and natural history and often lead to significant clinical problems relating to diagnosis and clinical management. Following the need to have updated guidelines on the management of benign focal liver lesions, the Scientific Societies mainly involved in their management have promoted the drafting of a new dedicat…
Leaching characteristics of Sc-enriched, Fe-depleted acidic slags
2022
Scandium is currently classified as a critical raw material for the European Union, and several research projects focus on the search for new sources to supply to its expected increasing demand. The Kiviniemi mafic intrusion in Finland is a potential primary source for Sc; at Kiviniemi, Sc occurs mainly within the lattices of ferrous silicates, clinopyroxene and amphibole. Some of the main challenges in leaching of Kiviniemi-type feed material are related to either the complexity of Fe and Ti separation from Sc-containing solutions or a possible gelation problem when leaching a material with a high SiO2 content. According to preliminary beneficiation tests, direct acid leaching of the Kivin…