showing 36 of ~574560 from 574555 documents
Les traditions techniques de la céramique dans la région des Trois-Lacs (Suisse) entre 3650 et 3000 av. n. è.
2021
International audience
Random Feature Approximation for Online Nonlinear Graph Topology Identification
2021
Online topology estimation of graph-connected time series is challenging, especially since the causal dependencies in many real-world networks are nonlinear. In this paper, we propose a kernel-based algorithm for graph topology estimation. The algorithm uses a Fourier-based Random feature approximation to tackle the curse of dimensionality associated with the kernel representations. Exploiting the fact that the real-world networks often exhibit sparse topologies, we propose a group lasso based optimization framework, which is solve using an iterative composite objective mirror descent method, yielding an online algorithm with fixed computational complexity per iteration. The experiments con…
Global Initiative for Asthma (GINA) Strategy 2021 - Executive summary and rationale for key changes
2021
Funder: Global Initiative for Asthma
Demasiada felicidad. Sobre la teoria de los afectos en Descartes y Leibniz
2021
Descartes y Leibniz figuran como pensadores opuestos en el ámbito de la filosofía moderna. Tras un período de influencia inicial, el pensador alemán habría sido un crítico severo de las tesis filosóficas del filósofo francés. Sin embargo, una lectura cuidadosa de las dispersas declaraciones leibnizianas a propósito de los afectos y su dimensión moral nos permitirán hacernos cargo de la distancia y cercanía entre el pensamiento de ambos. Para Descartes la felicidad está ligada a la voluntad, mientras que Leibniz será más fiel a la tradición intelectualista aristotélica, aunque su concepción de las emociones es, en muchos sentidos, asombrosamente similar.
Advancements in Sustainable PVDF Copolymer Membrane Preparation Using Rhodiasolv® PolarClean As an Alternative Eco-Friendly Solvent
2021
In this work, Rhodiasolv® PolarClean was employed as a more sustainable solvent for the preparation of poly(vinylidene fluoride-hexafluoropropylene) (PVDF-HFP) flat sheet membranes via phase inversion technique by coupling vapour induced phase separation (VIPS) and non-solvent induced phase separation (NIPS) processes. Preliminary calculations based on Hansen solubility parameters well predicted the solubilization of the polymer in the selected solvent. The effect of exposure time on humidity and the influence of polyethylene glycol (PEG), polyvinyl pyrrolidone (PVP) and sulfonated polyether sulfone (S-PES) on membrane properties and performance, were evaluated. Three different coagulation …
MultivariateApart: Generalized partial fractions
2021
We present a package to perform partial fraction decompositions of multivariate rational functions. The algorithm allows to systematically avoid spurious denominator factors and is capable of producing unique results also when being applied to terms of a sum separately. The package is designed to work in Mathematica, but also provides interfaces to the Form and Singular computer algebra systems. THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOVE
Measurement of the Absolute Branching Fraction of Ds+→τ+ντ via τ+→e+νeν¯τ
2021
Using a dataset of 6.32 fb^{-1} of e^{+}e^{-} annihilation data collected with the BESIII detector at center-of-mass energies between 4178 and 4226 MeV, we have measured the absolute branching fraction of the leptonic decay D_{s}^{+}→τ^{+}ν_{τ} via τ^{+}→e^{+}ν_{e}ν[over ¯]_{τ}, and find B_{D_{s}^{+}→τ^{+}ν_{τ}}=(5.27±0.10±0.12)×10^{-2}, where the first uncertainty is statistical and the second is systematic. The precision is improved by a factor of 2 compared to the previous best measurement. Combining with f_{D_{s}^{+}} from lattice quantum chromodynamics calculations or the |V_{cs}| from the CKMfitter group, we extract |V_{cs}|=0.978±0.009±0.012 and f_{D_{s}^{+}}=(251.1±2.4±3.0) MeV, r…
She-Coronavirus: How cartoonists reflected women health workers during the COVID-19 pandemic
2021
Women account for 70% of healthcare workers, so their role has been – and still is – fundamental in addressing and managing the current pandemic event caused by the SARS-CoV-2 coronavirus. Far from being an opportunity to highlight the importance of women in the field, the healthcare crisis, together with lockdown policies and care responsibilities, have contributed to increase the gender gap. To study the depiction of women healthcare professionals, this paper analyses 401 cartoons on the COVID-19 pandemic that depict healthcare workers. Most represent doctors as men and nurses as women, in roles subordinate to men. The representation of women is also impacted by stereotypes that do not c…
VentQsys: Low-cost open IoT system for CO2 monitoring in classrooms
2021
AbstractIn educational context, a source of nuisance for students is carbon dioxide ($$CO_2$$ C O 2 ) concentration due to closed rooms and lack of ventilation or circulatory air. Also, in the pandemic context, ventilation in indoor environments has been proven as a good tool to control the COVID-19 infections. In this work, it is presented a low cost IoT-based open-hardware and open-software monitoring system to control ventilation, by measuring carbon dioxide ($$CO_2$$ C O 2 ), temperature and relative humidity. This system provides also support for automatic updating, auto-self calibration and adds some Cloud and Edge offloading of computational features for mapping functionalities. From…
Potential of Baltic Region Peat in High Added-value Products and Environmentally Friendly Applications - A Review
2021
The present review is dedicated to using of peat on the example of fen peat in high added-value products and applications. Mainly, but not limited, last decade literature was analysed from the perspective of innovation potential of peat applications in environmental technologies on examples of studies from the Baltic Sea region. Paper covers a wide range of applications of peat products started from agriculture to medicine and cosmetics. A separate chapter is devoted to the deep-processed peat product - humic substances (humate, humic and fulvic salts and acids). Generalised dependence of product extraction rate and its properties, depending on the process parameters are provided. Widely ar…
In situ observations of CH<sub>2</sub>Cl<sub>2</sub> and CHCl<sub>3</sub…
2021
Abstract. Efficient transport pathways for ozone-depleting very short-lived substances (VSLSs) from their source regions into the stratosphere are a matter of current scientific debate; however they have yet to be fully identified on an observational basis. Understanding the increasing impact of chlorine-containing VSLSs (Cl-VSLSs) on stratospheric ozone depletion is important in order to validate and improve model simulations and future predictions. We report on a transport study using airborne in situ measurements of the Cl-VSLSs dichloromethane (CH2Cl2) and trichloromethane (chloroform, CHCl3) to derive a detailed description of two transport pathways from (sub)tropical source regions in…
COMPOSICIÓN QUIMICA DE LAS HOJAS y SEMILLAS DE SACHA INCHI (Plukenetia volubilis L.); OLEAMIDA
2021
El estudio se realiza con el objeto de identificar el tipo de alcaloide, protoalcaloide opseudoalcaloide, que puedan ser cuantificables en las hojas y en la torta desemillas tostadas y desengrasadas de la especie Plukenetia volubilis L. y demostrar que su presencia no representa un riesgo para la salud. La metodología utilizada está basada en protometría de acuerdo a la Farmacopea Francesa y Europea, así como la utilización de técnicas de UHPLC-MS/MS y GC-MS que han permitido identificar y cuantificar un compuesto endógeno que revela las características de la cis-9-octadecenamida (oleamida), estructura similar a la anandamida; ligando endógeno de receptores cannabinoides en concentraciones …
The Work of Special Education Teachers in the Tiered Support System: The Finnish Case
2021
Effectiveness of mindfulness-based interventions on psychotherapy processes: A systematic review.
2021
In the field of psychotherapy, scientific research has highlighted the importance of empathy and therapeutic alliance in regard to the effectiveness and better results of psychological treatments. In recent years, mindfulness-based interventions (MBIs) have shown to be effective at increasing empathy and therapeutic alliance and how this could affect the patients' symptomatology. In this study, we conducted a systematic review of the effectiveness of MBIs applied to psychotherapists to improve their empathy, the therapeutic alliance and the patients' symptomatology. Sixteen studies evaluating the impact of an MBI on some of these variables were identified, of which six included measures eva…
Body mass index categories and anxiety symptoms among adults aged =?50 years from low and middle income countries.
2021
Background: Body weight may be a risk factor for anxiety; however, there is a scarcity of studies on this association in older adults especially from low and middle income countries (LMICs). Therefore, we investigated the association between body mass index (BMI) and anxiety symptoms among adults aged ≥ 50 years from 6 LMICs. Methods: Cross-sectional, community-based, nationally representative data from the World Health Organization (WHO) Study on global AGEing and adult health (SAGE) were analyzed. The BMI was based on measured weight and height and was categorized as: < 18.5 kg/m2 (underweight), 18.5–24.9 kg/m2 (normal weight), 25.0–29.9 kg/m2 (overweight), 30.0–34.9 kg/m2 (obesity cla…
Aligning personal and collective interests in emerging adults during the COVID-19 emergency in Italy
2021
This study investigated the relations of emerging adults' personal (civic competence and interdependent self-construal) and community-based (sense of community and civic engagement) resources as predictors of appraisal of COVID-19 Public Health Emergency Management (PHEM) and attitudes toward preventing contagion in Italy. Participants were 2873 Italian emerging adults (71% females) aged 19-30 years (M = 22.67, SD = 2.82). Structural equation modeling revealed both direct and indirect positive associations among study variables. Civic competence and interdependent self-construal were related to sense of community and civic engagement behavior which, in turn, predicted appraisal of PHEM. App…
Investigating the Molecular Mechanism of H3B-8800: A Splicing Modulator Inducing Preferential Lethality in Spliceosome-Mutant Cancers.
2021
The SF3B1 protein, part of the SF3b complex, recognizes the intron branch point sequence of precursor messenger RNA (pre-mRNA), thus contributing to splicing fidelity. SF3B1 is frequently mutated in cancer and is the target of distinct families of splicing modulators (SMs). Among these, H3B-8800 is of particular interest, as it induces preferential lethality in cancer cells bearing the frequent and highly pathogenic K700E SF3B1 mutation. Despite the potential of H3B-8800 to treat myeloid leukemia and other cancer types hallmarked by SF3B1 mutations, the molecular mechanism underlying its preferential lethality towards spliceosome-mutant cancer cells remains elusive. Here, microsecond-long a…
Comparison of 2D versus 3D diffusion analysis at Nanowire Electrodes: Finite element analysis and experimental study
2021
In electroanalysis, finite element simulations of electrochemical processes occurring at electrodes are used to provide key insight into experimental design in relation to diffusion profiles and expected currents. The diffusion domain approach (DDA) offers a means of reducing a three dimensional design to two dimensions to ease computational demands. However, the DDA approach can be limited when basic assumptions, for example that all electrodes in an array are equivalent, are incorrect. Consequently, to get a more realistic view of molecular diffusion to nanoelectrodes, it is necessary to undertake simulations in 3D. In this work, two and three dimensional models of electrodes comprising o…
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2021
AIM: To investigate short- and long-term intraocular pressure (IOP) fluctuations and further ocular and demographic parameters as predictors for normal tension glaucoma (NTG) progression. METHODS: This retrospective, longitudinal cohort study included 137 eyes of 75 patients with NTG, defined by glaucomatous optic disc or visual field defect with normal IOP (<21 mm Hg), independently from therapy regimen. IOP fluctuation, mean, and maximum were inspected with a mean follow-up of 38mo [standard deviation (SD) 18mo]. Inclusion criteria were the performance of minimum two 48-hour profiles including perimetry, Heidelberg retina tomograph (HRT) imaging, and optic disc photographs. The impact …
Diffusion of theories and theoretical models in the Ibero‐American research on information behavior
2021
Ibero-American research on information behavior (IB) lacks the visibility typical of other parts of the world, and little is known about it in countries outside the area. The objective of this paper has therefore been to analyze the way in which Ibero-American research incorporates various theoretical references to empirical research on IB. The results point to the existence of different focuses of research in the past 10 years, in the sense of a reduced empirical approach and a moderate to minimal use of theories in the design of such research. Furthermore, the most cited theories and models of IB at an international level are those most widely applied in this geographical area, and the us…
Self-assembly of C60 fullerene molecules in the hexane–xylene solvent system
2021
The behavior of self-assembly of C60 molecules in solutions of C60/hexane/xylene were studied by the methods of refractometry, ultraviolet–visible spectroscopy and dynamic light scattering (DLS). I...
A dual process model to predict adolescents’ screen time and physical activity
2021
OBJECTIVE: Many adolescents report a lack of physical activity (PA) and excess screen time (ST). Psychological theories aiming to understand these behaviours typically focus on predictors of only one behaviour. Yet, behaviour enactment is often a choice between options. This study sought to examine predictors of PA and ST in a single model. Variables were drawn from dual process models, which portray behaviour as the outcome of deliberative and automatic processes. DESIGN: 411 Finnish vocational school students (age 17-19) completed a survey, comprising variables from the Reasoned Action Approach (RAA) and automaticity pertaining to PA and ST, and self-reported PA and ST four weeks later. M…
Signal-Processing and Adaptive Prototissue Formation in Metabolic DNA Protocells
2021
Abstract The fundamental life-defining processes in living cells, such as replication, division, adaptation, and tissue formation, take place via intertwined metabolic reaction networks orchestrating downstream signal processing in a confined, crowded environment with high precision. Hence, it is crucial to understand and reenact some of these functions in wholly synthetic cell-like entities (protocells) to envision designing soft-materials with life-like traits. Herein, we report on a programmable all-DNA protocell (PC) composed of a liquid DNA interior and a hydrogel-like shell, harboring DNAzyme active sites in the interior whose catalytic bond-cleaving activity leads to a downstream phe…
Conversion of Organic Dyes into Pigments: Extraction of Flavonoids from Blackberries (Rubus ulmifolius) and Stabilization
2021
The blackberry’s color is composed mainly of natural dyes called anthocyanins. Their color is red–purple, and they can be used as a natural colorant. Anthocyanins are flavonoids, which are products of plants, and their colors range from orange and red to various shades of blue, purple and green, according to pH. In this study, the chemical composition of an extract obtained from blackberries was defined by LC-ESI/LTQOrbitrap/MS in positive and negative ionization mode. Furthermore, we investigated the adsorption process of blackberry extract using several inorganic fillers, such as metakaolin, silica, Lipari pumice, white pozzolan and alumina. The pigments exhibit different colors as a func…
Density-dependent winter survival of immatures in an irruptive raptor with pulsed breeding
2021
Highly mobile predators can show strong numerical responses to pulsed resources, sometimes resulting in irruptions where large numbers of young invade landscapes at a continental scale. High production of young in irruption years may have a strong influence on the population dynamics unless immature survival is reduced compared to non-irruption years. This could occur if subordinate individuals (mainly immatures) are forced into suboptimal habitats due to density-dependent effects in irruption years. To test whether irruptive individuals had lower survival than non-irruptive ones, we combined necropsy results (N = 365) with telemetry (N = 185) from more than 20 years to record timing and ca…
Modulation of impulsive behaviours using transcranial random noise stimulation
2021
Neuvostoliitto ja suomalainen soitonopetus : rajoja ja mahdollisuuksia
2021
Artikkelissa käsitellään suomalaisen instrumenttiopetuksen kehitystä. Fokuksessa on Neuvostoliiton vaikutus erityisesti pianon- ja viulunsoiton opetukseen ajanjaksona, jolloin suomalainen musiikkikoulutus kehittyi voimakkaasti, 1960-luvulta 1980-luvulle. This article discusses the development of teaching of musical instruments in Finland. The focus is fixed on the Soviet impact during the decades when Finnish music education was strongly developing, from the 1960s to 1980s. The focus is, in particular, the teaching of two instruments, the piano and the violin. Both received still noticeable influences from the top musicians and their methods in Soviet Union. Attention is paid both on struct…
Disturbed Lipid Metabolism in Diabetic Patients with Manifest Coronary Artery Disease Is Associated with Enhanced Inflammation
2021
Background: Diabetic vasculopathy plays an important role in the pathophysiology of coronary artery disease (CAD) with oxidative stress as a strong mediator. This study aims to elucidate the underlying pathomechanisms of diabetic cardiac vasculopathy leading to coronary disease with an emphasis on the role of oxidative stress. Therefore, novel insights into antioxidant pathways might contribute to new strategies in the treatment and prevention of diabetic CAD. Methods: In 20 patients with insulin-dependent or non-insulin dependent diabetes mellitus (IDDM/NIDDM) and 39 non-diabetic (CTR) patients, myocardial markers of oxidative stress, vasoactive proteins, endothelial nitric oxide synthase …
Fostering Storytelling by Persons with Dementia in Multiparty Conversation
2021
Persons with dementia (PWDs) frequently find that communicative and cognitive problems may get in the way of participating in a multiparty conversation on a par with their healthy interlocutors. Such troubles may lead to their gradual withdrawal from involvement in the conversation and, if allowed to develop into a pattern, to even greater reductions in engagement in social interaction as a whole. This chapter describes strategies used by interlocutors to foster storytelling by PWDs and thus to counter this development. It investigates two extended cases from two very different types of interaction—an informal sociable lunchtime conversation with friends and a weekly meeting of an early mem…
Shedding Light on Graphene Quantum Dots: Key Synthetic Strategies, Characterization Tools, and Cutting-Edge Applications
2021
During the last 20 years, the scientific community has shown growing interest towards carbonaceous nanomaterials due to their appealing mechanical, thermal, and optical features, depending on the specific nanoforms. Among these, graphene quantum dots (GQDs) recently emerged as one of the most promising nanomaterials due to their outstanding electrical properties, chemical stability, and intense and tunable photoluminescence, as it is witnessed by a booming number of reported applications, ranging from the biological field to the photovoltaic market. To date, a plethora of synthetic protocols have been investigated to modulate the portfolio of features that GQDs possess and to facilitate the…
Comment on “Medication-Related Osteonecrosis of the Jaw (MRONJ)” by Elie M. Ferneini in the Section “Simply Put: JOMS Information for Patients”
2021
We read with great interest the contribute to the section “Simply Put: JOMS Information for Patients” named “Medication-Related Osteonecrosis of the Jaw (MRONJ)” by Elie M. Ferneini.
Cardiovascular responses to dynamic and static upper-body exercise in a cold environment in coronary artery disease patients
2021
Abstract Purpose Upper-body exercise performed in a cold environment may increase cardiovascular strain, which could be detrimental to patients with coronary artery disease (CAD). This study compared cardiovascular responses of CAD patients during graded upper-body dynamic and static exercise in cold and neutral environments. Methods 20 patients with stable CAD performed 30 min of progressive dynamic (light, moderate, and heavy rating of perceived exertion) and static (10, 15, 20, 25 and 30% of maximal voluntary contraction) upper body exercise in cold (− 15 °C) and neutral (+ 22 °C) environments. Heart rate (HR), blood pressure (BP) and electrocardiographic (ECG) responses were recorded an…
Quantum Probes for the Characterization of Nonlinear Media
2021
Active optical media leading to interaction Hamiltonians of the form H=λ˜(a+a†)ζ represent a crucial resource for quantum optical technology. In this paper, we address the characterization of those nonlinear media using quantum probes, as opposed to semiclassical ones. In particular, we investigate how squeezed probes may improve individual and joint estimation of the nonlinear coupling λ˜ and of the nonlinearity order ζ. Upon using tools from quantum estimation, we show that: (i) the two parameters are compatible, i.e., the may be jointly estimated without additional quantum noise
Melatonin Levels in Children with Obesity Are Associated with Metabolic Risk and Inflammatory Parameters
2021
Melatonin, the hormone of circadian rhythm regulation, is involved in the modulation of mitochondrial activity through its antioxidant and anti-inflammatory properties. Alteration of circadian rhythms such as sleep is related to obesity and metabolic pathogenesis in adulthood, but studies during childhood are scarce. The present study investigated the association of melatonin with metabolic and inflammatory markers in children with (n = 113) and without obesity (n = 117). Melatonin was measured in saliva four and two hours before bedtime, and after one hour of sleep. Cardiometabolic factors, high sensitivity C-reactive protein, immune markers (monocyte chemoattractant protein-1, plasminogen…
The catalytic effects of a thiazolium salt in the oxa-Diels–Alder reaction between benzaldehyde and Danishefsky's diene: a molecular electron density…
2021
The oxa-Diels–Alder (ODA) reaction of benzaldehyde with Danishefsky's diene in the presence of a [thiazolium][Cl] salt, as a model of an ionic liquid, has been studied within Molecular Electron Density Theory (MEDT) at the M06-2X/6-311G(d,p) computational level. The formation of two hydrogen bonds (HBs) between the thiazolium cation and the carbonyl oxygen of benzaldehyde modifies neither the electrophilic character of benzaldehyde nor its electronic structure substantially but accelerates the reaction considerably. This ODA reaction presents an activation energy of 4.5 kcal mol−1; the formation of the only observed dihydropyranone is strongly exothermic by −28.8 kcal mol−1. The presence of…
Postępowanie zabezpieczające w sprawach gospodarczych
2021
Celem artykułu jest omówienie wybranych instytucji postępowania zabezpieczającego w kontekście specyfiki spraw gospodarczych. Wnioski o udzielenie zabezpieczenia w tego typu sprawach wpływają do sądów dość często, zwłaszcza w sprawach o stwierdzenie nieważności uchwały bądź jej uchylenie. Orzeczenie sądu ma natomiast daleko idące skutki dla obrotu gospodarczego.