showing 36 of ~574560 from 574555 documents
The ICE-Q: A tool for the assessment of Psychological Adaptation Processes (PAP) in Isolated and Confined Extreme (ICE) environments
2021
International audience; Life in Isolated and Confined Extreme (ICE) environments poses important challenges and constraints and therefore to human adaptation and more particularly to the processes of psychological adaptation (PAP). Contemporary models view psychological adaptation as a dynamic process of constant adjustment to the environment, encompassing changes in physical, social and psychological demands and constraints (Cramer, 2000; Lazarus, 1991; Nicolas et al., 2017). The literature lacks valid and reliable measures of the psychological processes engaged in adaptation to the ICE environment (Sandal, Leon, & Palinkas, 2006). Monitoring can provide early warning of mission- and healt…
Athletes’ subjective evaluations of the implementation of dual career measures
2021
Spilling the beans: The development of conceptual knowledge about food and its links with food rejection in young children (3-7-years-old)
2021
Insufficient dietary variety in children leads to significant nutrient deficiencies and health issues, both in childhood and later life (DeCosta et al., 2017). Cognitive mechanisms, such as categorization and conceptual knowledge, play an important role in understanding and appropriately accepting or rejecting foods (Mura Paroche et al., 2017). The food domain lends itself to many concepts and categories, such as taxonomic (i.e., lamb is meat), thematic (i.e., lamb goes on a plate), or script (i.e., lamb is eaten at dinner). Such knowledge aids accurate recognition, understanding, and appropriate interaction when confronted with foods situated in context. If conceptual knowledge is underdev…
Regional inequalities, economic crises and policies: an international panel analysis
2021
This paper examines the effects of economic downturns on regional inequalities. In a sample of 25 OECD countries for 1990–2014 period, we show that economic downturns are associated with a significant and long-lasting reduction in regional inequalities. Expansionary fiscal policy as well as higher share of the European development (cohesion) funds facilitate the response of lagging regions to negative nation-wide shocks, contributing to further stimulate the reduction in regional disparities. Additional evidence suggests that the effect of downturns tends to be larger in economies with a higher initial level of regional disparities in unemployment and human capital endowment.
Organizing for collaboration in simulation-based environments: An affordance perspective
2021
Citizens’ perceptions in relation to transport systems and infrastructures: a nationwide study in the dominican republic
2021
One of the challenges currently faced by emerging countries is to get their citizens to decide to use sustainable transport for their regular trips, in order to reduce the current vehicular pollution rates. The objective of this descriptive research is to examine the perceptions of Dominicans regarding the state of the country’s transport systems and road infrastructure. For this purpose, a nationwide survey procedure was performed. This cross-sectional research used the data retrieved from a sample of 1260 citizens aged over 18, proportional in gender, age, habitat, and province of the Dominican Republic. The results showed how Dominicans believe that, compared to other road features, pede…
Energy compensation and adiposity in humans
2021
Publisher Copyright: © 2021 The Authors Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1–3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response—energy compensation. We used the largest dataset compiled on adult TEE and basal energy expenditure (BEE) (n = 1,754) of people living normal lives to fi…
New syntaxa of tall-forb vegetation in the Pamir-Alai and western Tian Shan Mts. (Tajikistan and Kyrgyzstan, Middle Asia) – an addendum to Nowak et a…
2021
We validate eleven syntaxa (eight associations and three alliances) of tall-forb vegetation that were published earlier as nomina provisoria according to the International Code of Phytosociological Nomenclature. The validation concerns syntaxa of tall-forb vegetation of the class Prangetea ulopterae Klein 1987 reported from Pamir-Alai and western Tian Shan Mountains (Tajikistan and Kyrgyzstan). Taxonomic reference: Cherepanov (1995). Abbreviations: ICPN = International Code of Phytosociological Nomenclature.
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2021
FTIR spectroscopy was combined with the matrix isolation technique and quantum chemical calculations with the aim of studying complexes of isocyanic acid with sulfur dioxide. The structures of the HNCO⋯SO2 complexes of 1:1, 1:2 and 2:1 stoichiometry were optimized at the MP2, B3LYPD3, B2PLYPD3 levels of theory with the 6-311++G(3df,3pd) basis set. Five stable 1:1 HNCO⋯SO2 complexes were found. Three of them contain a weak N-H⋯O hydrogen bond, whereas two other structures are stabilized by van der Waals interactions. The analysis of the HNCO/SO2/Ar spectra after deposition indicates that mostly the 1:1 hydrogen-bonded complexes are present in argon matrices, with a small amount of the van de…
Metabolism of third generation synthetic cannabinoids using zebrafish larvae.
2021
Synthetic cannabinoids are the second largest group of new psychoactive substances reported by the United Nations Office on Drugs and Crime in the last decade and case reports bring attention to its high potency effects and its severe toxicity, including fatalities. Moreover, synthetic cannabinoids are usually entirely metabolized and metabolic pathways for many new generation synthetic cannabinoids are still unknown. In this study, the metabolism of five third generation synthetic cannabinoids were evaluated using zebrafish (Danio rerio) larvae as 24-hours in vivo model studied within 5 days after fertilization. The studied synthetic cannabinoids were MMB-CHMICA, ADB-CHMICA, ADB-CHMINACA, …
Introducing Traceability in GitHub for Medical Software Development
2021
Assuring traceability from requirements to implementation is a key element when developing safety critical software systems. Traditionally, this traceability is ensured by a waterfall-like process, where phases follow each other, and tracing between different phases can be managed. However, new software development paradigms, such as continuous software engineering and DevOps, which encourage a steady stream of new features, committed by developers in a seemingly uncontrolled fashion in terms of former phasing, challenge this view. In this paper, we introduce our approach that adds traceability capabilities to GitHub, so that the developers can act like they normally do in GitHub context bu…
Advanced computation in cardiovascular physiology: New challenges and opportunities
2021
Recent developments in computational physiology have successfully exploited advanced signal processing and artificial intelligence tools for predicting or uncovering characteristic features of physiological and pathological states in humans. While these advanced tools have demonstrated excellent diagnostic capabilities, the high complexity of these computational 'black boxes’ may severely limit scientific inference, especially in terms of biological insight about both physiology and pathological aberrations. This theme issue highlights current challenges and opportunities of advanced computational tools for processing dynamical data reflecting autonomic nervous system dynamics, with a speci…
Information decomposition in the frequency domain: a new framework to study cardiovascular and cardiorespiratory oscillations
2021
While cross-spectral and information-theoretic approaches are widely used for the multivariate analysis of physiological time series, their combined utilization is far less developed in the literature. This study introduces a framework for the spectral decomposition of multivariate information measures, which provides frequency-specific quantifications of the information shared between a target and two source time series and of its expansion into amounts related to how the sources contribute to the target dynamics with unique, redundant and synergistic information. The framework is illustrated in simulations of linearly interacting stochastic processes, showing how it allows us to retrieve …
« « Goûtez l’Ardèche », valorisation d’une marque collective »
2021
International audience
Paramedics’ knowledge of medical guidelines and procedures for protection against coronavirus during the COVID-19 pandemic: a pilot study
2021
Background: Paramedics are the frontline workers of the healthcare profession. Thus, they need to be equipped with the relevant knowledge, skills, and protective gear against different forms of infection, including coronavirus disease 2019 (COVID-19). Aim of the study: To determine the level of paramedics’ knowledge about implementing medical guidelines and procedures to avoid coronavirus infection during the COVID-19 pandemic. Material and methods: This study involved 101 paramedics employed in Emergency Medical Services in Legnica between November 2020 and January 2021. A diagnostic survey method and opinion polling technique were applied. A survey developed by the study authors was used.…
Tracking of Quantized Signals Based on Online Kernel Regression
2021
Kernel-based approaches have achieved noticeable success as non-parametric regression methods under the framework of stochastic optimization. However, most of the kernel-based methods in the literature are not suitable to track sequentially streamed quantized data samples from dynamic environments. This shortcoming occurs mainly for two reasons: first, their poor versatility in tracking variables that may change unpredictably over time, primarily because of their lack of flexibility when choosing a functional cost that best suits the associated regression problem; second, their indifference to the smoothness of the underlying physical signal generating those samples. This work introduces a …
Intraoral onlay block bone grafts versus cortical tenting technique on alveolar ridge augmentations: a systematic review
2021
To review systematically the bone gain and superficial resorption rate of the onlay block bone grafts versus the cortical tenting technique, as well as secondarily study the postoperative complications, implant survival and success rates, and peri-implant marginal bone loss. Following the recommended methods for systematic reviews and meta-analyses (PRISMA), an electronic search was performed in the PubMed (MEDLINE), EMBASE and the Cochrane Library of the Cochrane Collaboration (CENTRAL) databases to identify all relevant articles published up to March 2021 on onlay block bone grafts and cortical tenting technique. Eighteen papers complied with the inclusion criteria. In onlay grafts, the v…
Social Pedagogy as an offer of master’s studies in Poland after the Second World War (1945-1950)
2021
The article presents graduate programs (Masters level) in the field of social pedagogy offered by Helena Radlińska and her colleagues at the University of Łódz after WWII. Socio-Pedagogical studies established at the Department of Social Pedagogy at the University of Łódz were supposed to prepare educational, social, and cultural workers in time of revival of Poland after 1945. The example of the educational model created at that time can serve as an inspiration in the development of contemporary programs of education rooted in the Polish socio-pedagogical tradition.
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2021
BACKGROUND The aim of this study was to identify risk factors for surgical complications after anatomic lung resections in the era of video-assisted thoracic surgery (VATS) and enhanced recovery after surgery (ERAS). METHODS A retrospective analysis of all consecutive adult patients who underwent elective anatomic lung resections between January and December 2020 at our institution was performed. RESULTS Eighty patients (40 VATS, 40 thoracotomy) were included. The 30-day mortality rate was 1.3%. The overall rate of major postoperative complications was 18.8%. Most major complications occurred in patients who underwent open surgery (complication rate 32.5%, share of total complications 86.7%…
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2021
To what extent the intake of fruit and vegetables (FV) influences inflammatory status remains elusive, particularly in older populations. The aim of the present study was to determine the effect of increased FV intake for 16 weeks on circulating biomarkers of inflammation in a population of older men and women. Sixty-six participants (65–70 years) randomly assigned to either FV or control (CON) groups were instructed to increase FV intake to five servings per day through nutritional counseling (FV) or to maintain habitual diet (CON). Dietary intake and physical activity level (PA) were determined using food frequency questionnaire and accelerometers, respectively, at the start and end of th…
Using self-controlled case series to understand the relationship between conflict and cholera in Nigeria and the Democratic Republic of Congo
2021
Abstract Background Cholera outbreaks contribute significantly to diarrhoeal disease mortality, especially in low-income countries. Cholera outbreaks have several social and environmental risk factors and extreme conditions can act as catalysts for outbreaks. A social extreme with known links to infectious disease outbreaks is conflict, causing disruption to services, loss of income and displacement. Methods Here, we explored this relationship in Nigeria and the Democratic Republic of Congo (DRC), by fitting publicly available cholera and conflict data to conditional logistic regression models. We used the self-controlled case series method in a novel application, to understand if an exposu…
Tickle contagion in the somatosensory cortex
2021
AbstractThe cellular mechanisms of emotional contagion are unknown. We investigated tickle contagion and the underlying neuronal representations in rats. We recorded trunk somatosensory cortex activity of observer rats while they received tickling, audio-visual playback of tickling footage, and while they witnessed tickling of demonstrator rats. Observers vocalized, and showed “Freudensprünge” (“joy jumps”) during witnessing live tickling, while they showed little behavioral responses to playbacks. A fraction of trunk somatosensory neurons responded to both direct and witnessed tickling in action-specific manner. The correlation between direct and witnessed tickling responses increased towa…
INFLUENCE OF INTEREST GROUPS IN LATVIA ON CENTRALIZATION
2021
Latvia has experienced four administrative-territorial reforms in 30 years. In 1989, local and regional elections were the first democratic elections in Latvia since 1934. From 1990 to 1992, self-governments were the main authority for re-establishing national independence and transforming the country from totalitarianism to democracy. The transformation process starts with wide decentralization, including substantial fiscal decentralization and substantial administrative decentralization.
 The first reform was the centralization (1994) of Rīga city government (1 self-government instead of a two-tier system, with 6 district local governments and 1 city local government). The second re…
Nonlinear concave-convex problems with indefinite weight
2021
We consider a parametric nonlinear Robin problem driven by the p-Laplacian and with a reaction having the competing effects of two terms. One is a parametric (Formula presented.) -sublinear term (concave nonlinearity) and the other is a (Formula presented.) -superlinear term (convex nonlinearity). We assume that the weight of the concave term is indefinite (that is, sign-changing). Using the Nehari method, we show that for all small values of the parameter (Formula presented.), the problem has at least two positive solutions and also we provide information about their regularity.
Predicting Next Dialogue Action in Emotionally Loaded Conversation
2021
This paper reports on creating a neural network model for prediction of the next action in a dialogue considering conversation history, i.e. entities, context variables and emotion indicators marking emotionally loaded user utterances. Several experiments were performed to see how the information about emotions affects the accuracy of the model. For the purposes of these experiments, a dataset containing 206 dialogs in Latvian in the transport inquiry domain was created containing both neutral and emotionally loaded utterances. To see if the proposed next dialogue action prediction model architecture is suitable for other languages, the original Latvian utterances were translated into Engli…
A Randomised-Controlled Clinical Study Examining the Effect of High-Intensity Laser Therapy (HILT) on the Management of Painful Calcaneal Spur with P…
2021
Calcaneal spur and plantar fasciitis are the most common causes of plantar heel pain. There are many effective physical modalities for treating this musculoskeletal disorder. So far, the are no clear recommendations confirming the clinical utility of high-intensity laser therapy (HILT) in the management of painful calcaneal spur with plantar fasciitis. This study aimed to evaluate the effectiveness of HILT in pain management in patients with calcaneal spur and plantar fasciitis. A group of 65 patients was assessed for eligibility based on the CONSORT guidelines. This study was prospectively registered in the Australian New Zealand Clinical Trial Registry platform (registration number ACTRN1…
Translational Model of Cortical Premotor-Motor Networks.
2021
Abstract Deciphering the physiological patterns of motor network connectivity is a prerequisite to elucidate aberrant oscillatory transformations and elaborate robust translational models of movement disorders. In the proposed translational approach, we studied the connectivity between premotor (PMC) and primary motor cortex (M1) by recording high-density electroencephalography in humans and between caudal (CFA) and rostral forelimb (RFA) areas by recording multi-site extracellular activity in mice to obtain spectral power, functional and effective connectivity. We identified a significantly higher spectral power in β- and γ-bands in M1compared to PMC and similarly in mice CFA layers (L) 2/…
Improving the Long‐Term Stability of Doped Spiro‐Type Hole‐Transporting Materials in Planar Perovskite Solar Cells
2021
The improvement of the long-term stability of perovskite-based solar cells (PSCs) toward commercialization is closely linked to the development of cutting-edge charge-transporting materials. The progress on the design and the synthesis of new hole-transporting materials (HTMs) is synergistically attaining both top efficiencies and promising stability. Herein, the synthesis and characterization of two doped-HTMs based on electron-rich spiranic cores, namely, 9H-quinolinophenoxazine (spiro-POZ) and 9H-quinolinophenothiazine (spiro-PTZ), are presented. The novel HTMs exhibit excellent solubility, optimal highest occupied molecular orbital energy, and excellent thermal stability with glass tran…
Effects of shear flow on the structure and dynamics of ionic liquids in a metallic nanoconfinement.
2021
It has been shown that a weak shear can induce crystallisation in a disordered, glassy state. In this study, we use molecular dynamics simulations in order to investigate the out-of-equilibrium properties of [BMIM][BF4] confined between metal slabs. In particular, we want to understand the extent to which the shear flow modifies the interfacial properties. In particular, the questions we address here are (i) is the shear able to promote the crystalline phase in [BMIM][BF4]? (ii) Can, as a consequence of shear flow, a solid-like layer develop at the interface with a metallic surface? (iii) What are the tribological properties of nanoconfined [BMIM][BF4]? We find that the system behaves quite…
Combined assessment of stress cardiovascular magnetic resonance and angiography to predict the effect of revascularization in chronic coronary syndro…
2021
Abstract Aims The role of revascularization in chronic coronary syndrome (CCS) and the value of ischaemia vs. anatomy to guide decision-making are in constant debate. We explored the potential of a combined assessment of ischaemic burden by vasodilator stress cardiovascular magnetic resonance (CMR) and presence of multivessel disease by angiography to predict the effect of revascularization on all-cause mortality in CCS. Methods and results The study group comprised 1066 CCS patients submitted to vasodilator stress CMR pre-cardiac catheterization (mean age 66 ± 11 years, 69% male). Stress CMR-derived ischaemic burden (extensive if >5 ischaemic segments) and presence of multivessel di…
Mathematical Modelling of Leukemia Treatment
2021
Leukemia is a cancer that can be treated in a variety of ways: chemotherapy, radiation therapy and stem cell transplant. Recovery rates for this disease are relatively high, the treatment itself has a painful effect on the body and is accompanied by numerous side effects that can persist years after the patient is cured. For this reason, efforts are underway worldwide to develop more selective therapies that will only affect leukemia cells and not healthy cells. Knowledge of developmental GRN is yet scarce, and it is early for a systematic comparative effort. We consider mathematical model of genetic regulatory networks. This model consists of a nonlinear system of ordinary differential equ…
Anisotropic flow of identified hadrons in Xe-Xe collisions at √sNN = 5.44 TeV
2021
Measurements of elliptic (v2) and triangular (v3) flow coefficients of π±, K±, p+p¯, K0S, and Λ+Λ¯ obtained with the scalar product method in Xe-Xe collisions at √sNN = 5.44 TeV are presented. The results are obtained in the rapidity range |y| < 0.5 and reported as a function of transverse momentum, pT, for several collision centrality classes. The flow coefficients exhibit a particle mass dependence for pT < 3 GeV/c, while a grouping according to particle type (i.e., meson and baryon) is found at intermediate transverse momenta (3 < pT < 8 GeV/c). The magnitude of the baryon v2 is larger than that of mesons up to pT = 6 GeV/c. The centrality dependence of the shape evolution of the pT-diff…
Co-simulation and Formal Verification of Co-operative Drone Control With Logic-Based Specifications
2021
Abstract Unmanned aerial vehicle (UAV) co-operative systems are complex cyber-physical systems that integrate a high-level control algorithm with pre-existing closed implementations of lower-level vehicle kinematics. In model-driven development, simulation is one of the techniques that are usually applied, together with testing, in the analysis of system behaviours. This work proposes a method and tools to validate the design of UAV co-operative systems based on co-simulation and formal verification. The method uses the Prototype Verification System, an interactive theorem prover based on a higher-order logic language, and the Functional Mock-up Interface, a widely accepted standard for co-…
Training During the COVID-19 Lockdown: Knowledge, Beliefs, and Practices of 12,526 Athletes from 142 Countries and Six Continents
2021
Abstract Objective Our objective was to explore the training-related knowledge, beliefs, and practices of athletes and the influence of lockdowns in response to the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods Athletes (n = 12,526, comprising 13% world class, 21% international, 36% national, 24% state, and 6% recreational) completed an online survey that was available from 17 May to 5 July 2020 and explored their training behaviors (training knowledge, beliefs/attitudes, and practices), including specific questions on their training intensity, frequency, and session duration before and during lockdown (March–Jun…
Exploring coherence and authorship in pedagogical link-making in science
2021
Despite rapid changes in education, science classrooms will remain central forums where fragmented pieces of information are brought together to construct coherent knowledge as concepts and explana...
The Effect of tRNA
2021
Transfer RNA[Ser]Sec carries multiple post-transcriptional modifications. The A37G mutation in tRNA[Ser]Sec abrogates isopentenylation of base 37 and has a profound effect on selenoprotein expression in mice. Patients with a homozygous pathogenic p.R323Q variant in tRNA-isopentenyl-transferase (TRIT1) show a severe neurological disorder, and hence we wondered whether selenoprotein expression was impaired. Patient fibroblasts with the homozygous p.R323Q variant did not show a general decrease in selenoprotein expression. However, recombinant human TRIT1R323Q had significantly diminished activities towards several tRNA substrates in vitro. We thus engineered mice conditionally deficient in Tr…