showing 36 of ~574560 from 574555 documents
Sulfate sensitivity of aquatic organism in soft freshwaters explored by toxicity tests and species sensitivity distribution
2023
Elevated concentrations of sulfate in waterways are observed due to various anthropogenic activities. Elevated levels of sulfate can have harmful effects on aquatic life in freshwaters: sulfate can cause osmotic stress or specific ion toxicity in aquatic organisms, especially in soft waters where Ca2+ and Mg2+ concentrations are low. Formerly, chronic toxicity test data in soft water have been scarce. The chronic and acute sulfate toxicity tests conducted with aquatic organisms from 10 families across various trophic levels in this study multiplied the number of tests conducted in soft freshwater conditions and enabled derivation of the species sensitivity distribution (SSD) and sulfate haz…
The EU-funded I3LUNG Project:Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy
2023
Although immunotherapy (IO) has changed the paradigm for the treatment of patients with advanced non-small cell lung cancers (aNSCLC), only around 30% to 50% of treated patients experience a long-term benefit from IO. Furthermore, the identification of the 30 to 50% of patients who respond remains a major challenge, as programmed Death-Ligand 1 (PD-L1) is currently the only biomarker used to predict the outcome of IO in NSCLC patients despite its limited efficacy. Considering the dynamic complexity of the immune system-tumor microenvironment (TME) and its interaction with the host's and patient's behavior, it is unlikely that a single biomarker will accurately predict a patient's outcomes. …
Un caso di pericardite recidivante colchicina-resistente
2023
La pericardite è una patologia infiammatoria del pericardio che si manifesta con dolore toracico e che spesso, ma non sempre, si associa a versamento pericardico. Rappresenta circa il 5% degli accessi in Pronto Soccorso (PS) per dolore toracico (di cui è la principale causa in età pediatrica). Le pericarditi si classificano a seconda della durata della sintomatologia o in base all’agente eziologico. A seconda della durata della sintomatologia si distinguono: forme acute, forme ricorrenti, quando si assiste a una ricomparsa dei sintomi dopo un periodo libero di almeno 6 settimane, e forme persistenti, quando i sintomi perdurano oltre le 6 settimane o quando si verifica una ricaduta del quadr…
Role of MRI in the Assessment of Cervical Cancer
2023
: Cervical cancer is the fourth most common cancer in women, and it is divided into 2 main histological types: squamous cell carcinoma and adenocarcinoma. Extension of disease as well as the presence of metastases define the prognosis of patients. Accurate tumor staging at diagnosis is essential for adequate planning for treatment. There are several classifications of cervical cancer, and the most used are FIGO and TNM, which help classify the patient and guide the treatment. Imaging has a pivotal role in classifying patients, and MRI plays a decision-maker role both for diagnosis and for treatment planning. In this paper we highlight the role of MRI, alongside guidelines classification, in…
Estimating soil moisture content under grassland with hyperspectral data using radiative transfer modelling and machine learning
2023
The monitoring of soil moisture content (SMC) at very high spatial resolution (10m) using unmanned aerial systems (UAS) is of high interest for precision agriculture and the validation of large scale SMC products. Data-driven approaches are the most common method to retrieve SMC with UAS-borne data at water limited sites over non-disturbed agricultural crops. A major disadvantage of data-driven algorithms is the limited transferability in space and time and the need of a high number of ground reference samples. Physically-based approaches are less dependent on the amount of samples and are transferable in space and time. This study explores the potential of (1) a hybrid method targeting the…
Architettura per i beni confiscati : figure del progetto nei territori del conflitto fra democrazia e criminalità
2023
L’articolo affronta il rapporto fra città, territorio e democrazia a partire dai risultati di una ricerca internazionale, che ha indagato le forme peculiari di crisi del pubblico nei territori del conflitto fra Stato e criminalità mafiosa. Le domande di ricerca si situano in un quadro che intende il territorio come luogo elettivo per leggere le tracce costruite dal rapporto fra comunità e poteri illegali. Esse hanno posto la necessità di indagare l’insieme dei beni confiscati reclamando la necessità dell’intervento progettuale per le trasformazioni spaziali, linguistiche e simboliche senza le quali la loro transizione a beni pubblici non può dirsi pienamente compiuta. Riferiti al terr…
Brief emotional eating scale : A multinational study of factor structure, validity, and invariance
2023
Emotional eating or the tendency to eat in response to emotional states can be assessed using self-report measures. The Emotional Eating Scale-II is a commonly used and reliable instrument that measures the desire to eat in response to a range of unpleasant and pleasant emotions. The current study aimed to corroborate the validity of the EES-II and expand its utility by investigating its dimensionality and testing its measurement invariance in samples from English-speaking and non-English-speaking countries. Convergent and predictive validity in respect of food craving, eating, and health indicators were also examined. This cross-national study included a total of 2485 adult participants re…
ReO as a Brønsted acidic modifier in glycerol hydrodeoxygenation : Computational insight into the balance between acid and metal catalysis
2023
A computational study for the competitive conversion of glycerol to 1,2-propanediol and 1,3-propanediol is presented, considering a two-step sequence of dehydration followed by hydrogenation. The elementary steps for dehydration, i.e., breaking of C–H followed by C–OH or vice versa, were studied computationally both on the Rh metal surface and the acid-modified ReOH–Rh surface in order to understand the role of the acid promoter. While the acid modifier can catalyze the C–OH cleavage, the activation energy for the C–H cleavage was found to be considerably smaller on both pure and acid-doped Rh(111) surfaces, and breaking the secondary C–H bond is kinetically favored over breaking the termin…
Self-confidence predicts entrepreneurship and entrepreneurial success
2023
THE ROLE OF PATIENT-PHYSICIAN RELATIONSHIP IN CARE PROCESSES AND IN THE TECHNOLOGICAL TRANSITION OF HEALTHCARE
2023
Rimpatriati in terra straniera: Ragonese, Capretti, Samaritano e Costantini raccontano la "jaala"
2023
La “cacciata” degli italiani dalla Libia, nel 1970, coinvolse circa 20.000 persone che, nate in Libia, si sono ritrovate improvvisamente strappate dalla quotidianità e catapultati in un'Italia a loro assolutamente estranea e solo idealmente custode della loro cultura originaria. Questo lavoro presenta, a titolo esemplificativo, alcuni testi narrativi neocoloniali e neostorici di Rita Ragonese, Luciana Capretti, Andrea Amedeo Sammartano e Roberto Costantini che raccontano delle angosce, e del profondo senso di spaesamento sofferto da migliaia di italiani rimpatriati con la forza in una patria sconosciuta. The “expulsion” of the Italians from Libya, in 1970, involved about 20,000 people who, …
New Challenges in Economic and Business Development – 2023: Recovery and Resilience: PROCEEDINGS; (15th International Scientific Conference, May 11-1…
2023
This year's conference is devoted to the challenges related to the recovery and resilience. Recovery and Resilience Facility is an important component of the European recovery plan (the Next Generation EU) which aims to overcome the economic and social effects of the Covid-19 pandemic and ensure better resilience of the EU Member States in the future. The objective of the conference was to provide a platform/opportunity for scholars, researchers and professionals from different disciplinary backgrounds to meet, exchange ideas, findings, research results and discuss challenges and prospects for economic and business development.
Changes in soil hydrodynamic parameters during intermittent rainfall following tillage
2023
The changes in the soil hydrodynamic properties following soil tillage were investigated in rainfall simulation trials of intermittent rain at the Masse experimental station (Soil Erosion LABoratory, SERLAB) in central Italy. The experiments were designed to build a database as representative as possible of situations that may occur in nature. The data collected during the experiments were used to determine the saturated soil hydraulic conductivity, Ks, the soil sorptivity at the antecedent soil–water matric potential Ψi, S, and the flow-weighted mean pore size at Ψi, λm. It was also verified if the energy content of total rainfall after tillage explained the short-term temporal variability…
Extracellular vesicles from PBDE-47 treated M(LPS) THP-1 macrophages modulate the expression of markers of epithelial integrity, EMT, inflammation an…
2023
Aims: The lung epithelial cells form a physical barrier to the external environment acting as the first line of defence against potentially harmful environmental stimuli. These cells interact with several other cellular components, of which macrophages are some of the most relevant. We analysed the effects of the PBDE-47 on the microRNA cargo of THP-1 macrophage like derived small Extracellular Vesicles (sEVs) and the effects on A549 lung epithelial cells. Main methods: sEVs from M(LPS) THP-1 macrophage-like cells after PBDE-47 treatment (sEVsPBDE+LPS) were characterized by nanoparticle tracking analysis and their microRNA cargo studied by qPCR. Confocal microscopy was applied to study sEVs…
Contaminant-induced oxidative stress underlies biochemical, molecular and fatty acid profile changes, in gilthead seabream (Sparus aurata L.)
2023
: Chemical contaminants such as heavy metals, polybrominated diphenyl ethers (PBDEs) and drugs, are constantly found in the marine environment determining the interest of the scientific community for their side effects on animal welfare, food safety and security. Few studies have analyzed the effects of mix of contaminants in fish, in terms of molecular and nutritional composition response, beside it is indispensable to think more and more on effect of contaminants along the food web system. In this study, Sparus aurata specimens were exposed for 15 days, by diet, to a mixture of carbamazepine (Cbz), polybrominated diphenyl ether-47 (PBDE-47) and cadmium chloride (CdCl2), at two doses (0.37…
Offline commissioning of a new gas cell for the MARA Low-Energy Branch
2023
Results of offline commissioning tests for a new dedicated gas cell for the Mass Analysing Recoil Apparatus (MARA) Low-Energy Branch are reported. Evacuation time, ion survival and transport efficiency in helium buffer gas were characterized with a radioactive 223Ra 𝛼-recoil source. Suppression of the ion signal, originating from non-neutralized species in the gas cell, was explored with 219Rn ions, the daughter recoil of 223Ra, as a function of voltage applied to one of the ion-collector electrodes. Two-step laser resonance ionization of stable tin isotopes produced inside the gas cell from a heated bronze filament was demonstrated, and broadening of the atomic resonances in argon buffer …
Flax–Glass Fiber Reinforced Hybrid Composites Exposed to a Salt-Fog/Dry Cycle: A Simplified Approach to Predict Their Performance Recovery
2023
Despite natural fibers gaining significant attention in recent decades, their limited performance and poor durability under humid environments cannot allow them to fully replace their synthetic counterparts as reinforcement for structural composites. In such a context, this paper aims to investigate how exposure to a humid/dry cycle affects the mechanical response of epoxy laminates reinforced with flax and glass fibers. In particular, the main goal is to assess the performance evolution of a glass–flax hybridized stacking sequence in comparison with the full glass and flax fiber reinforced composites. To this end, the investigated composites were first exposed to salt-fog for 15 or 30 days…
Le radici del futuro. Il Micromuseo Immateriale del Grano e del Pane. Un progetto design-driven per il patrimonio culturale rurale
2023
Realizzato nel 2016 nel borgo rurale Santa Rita nei pressi di Caltanissetta, il Micromuseo Immateriale del Grano e del Pane è un piccolo ecomuseo di identità e territorio, che coniuga la dimensione storico-antropologica della memoria con la dimensione scientifico-didattica legata ai saperi del grano e del pane. Nel palazzetto baronale, ex scuola del borgo, trovano posto installazioni interattive/sensoriali e artefatti di comunicazione immateriali (infografiche, animazioni, documentari) che costituiscono il focus dell’esperienza di visita al museo. Un progetto design-driven di “riuso” del patrimonio culturale come motore di sviluppo, sostenibile e condiviso, concepito e realizzato (con tecno…
L'equa remunerazione degli autori e degli artisti dopo l'attuazione della Direttiva 2019/790
2023
This essay focuses on the equalization remedies introduced by Articles 107, paragraph 2 and 110-quinquies of the l.a., transposing Articles 18 and 20 of EU Directive 2019/790. In particular, it brings the right to adequate and proportionate remuneration back to a form of protection of the weak contracting party assisted by an invalidating remedy corrected by a necessary partial nullity rule; and excludes that the adjustment mechanism can be brought back within the framework of the hardship clause.
Gastrointestinal Stromal Tumors: Diagnosis, Follow-up and Role of Radiomics in a Single Center Experience
2023
: Gastrointestinal stromal tumors (GISTs) arise from the interstitial cells of Cajal in the gastrointestinal tract and are the most common intestinal tumors. Usually GISTs are asymptomatic, especially small tumors that may not cause any symptoms and may be found accidentally on abdominal CT scans. Discovering of inhibitor of receptor tyrosine kinases has changed the outcome of patients with high-risk GISTs. This paper will focus on the role of imaging in diagnosis, characterization and follow-up. We shall also report our local experience in radiomics evaluation of GISTs.
Descrizione della Palestina nella riḥla maggiore dello šayḫ ‛Abd al-Ġanī al-Nābulusī (1641-1731)
2023
L’assenza di testi di Storia in lingua araba che affrontino complessivamente il periodo di governo ottomano in Palestina – lacuna che soltanto di recente, e in modo discontinuo, si è iniziato a colmare – tende a far privilegiare l’uso di altra tipologia di documenti, quali i siǧillāt (registri) conservati nei tribunali e negli archivi della regione, i kutub tarāǧim, o dizionari biografici, le mudhakkirāt, o memorie, e i resoconti di viaggio. La riḥla intitolata Al-ḥaqīqa wa’l-maǧāz fī riḥlat Bilād al-Šām wa Miṣr wa’l-Ḥiǧāz del noto šayḫ di origini damascene ‛Abd al-Ġanī al-Nābulusī (1641-1731), che è il più ampio tra i suoi resoconti di viaggio, e che il ‛ālim ha condotto sullo scorcio del …
Soil moisture variations from boreal forests to the tundra
2023
Soil moisture has a profound influence on life on Earth, and this vital water resource varies across space and time. Here, we explored soil moisture variations in boreal forest and tundra environments, where comprehensive soil moisture datasets are scarce. We installed soil moisture sensors up to 14 cm depth at 503 measurement sites within seven study areas across northern Europe. We recorded 6,138,528 measurements to capture soil moisture variations of the snowless season from April to September 2020. We described the spatio-temporal patterns of soil moisture, and test how these patterns are linked to topography and how these links vary in space and time. We found large spatial variation a…
Moving forward the Italian nursing education into the post-pandemic era: findings from a national qualitative research study
2023
Background: During the CoronaVIrus-19 (COVID-19) pandemic, nursing education has been dramatically transformed and shaped according to the restrictions imposed by national rules. Restoring educational activities as delivered in the pre-pandemic era without making a critical evaluation of the transformations implemented, may sacrifice the extraordinary learning opportunity that this event has offered. The aim of this study was to identify a set of recommendations that can guide the Italian nursing education to move forward in the post-pandemic era. Methods: A qualitative descriptive design was undertaken in 2022–2023 and reported here according to the COnsolidated criteria for REporting Qual…
Conversazioni umane e artificiali
2023
C’è una caratteristica centrale che distingue ChatGPT e simili da un interlocutore umano: pur sapendo rispondere in modo coerente e creativo a richieste anche complesse, sono del tutto incapaci di proporre contenuti conversazionali non puramente reattivi, manca, all’AI, la parte “affiliativa” della conversazione
Caratterizzazione qualitativa e nutrizionale di spaghetti integrali arricchiti con farine di lenticchie
2023
Nell’ambito del progetto ALIFUN - Sviluppo di alimenti funzionali per l’innovazione dei prodotti alimentari di tradizione italiana- al fine di sviluppare prototipi di alimenti funzionali a base di cereali innovativi impiegando matrici alimentari tipiche della tradizione italiana, sono state prodotte paste funzionalizzate attraverso l’utilizzo di semola integrale della cv Russello e di farina di lenticchie di una popolazione locale siciliana, reperita nell’areale ragusano. Sono stati prodotti 3 tipi di spaghetti: (RG) con il 40% (p/p) di farine di lenticchie, (RG+Guar) 40% (p/p) di lenticchie+2% Guar e (CTRL) semola integrale della cv. Russello. Sulle paste prodotte sono state determinate le…
Sustainable soy protein microsponges for efficient removal of lead (II) from aqueous environments
2023
Protein-based materials recently emerged as good candidates for water cleaning applications, due to the large availability of the constituent material, their biocompatibility and the ease of preparation. In this work, new adsorbent biomaterials were created from Soy Protein Isolate (SPI) in aqueous solution using a simple environmentally friendly procedure. Protein microsponge-like structures were produced and characterized by means of spectroscopy and fluorescence microscopy methods. The efficiency of these structures in removing Pb2+ ions from aqueous solutions was evaluated by investigating the adsorption mechanisms. The molecular structure and, consequently, the physico-chemical propert…
The legacy of human use in Amazonian palm communities along environmental and accessibility gradients
2023
Aim: Palms are iconic and dominant elements of neotropical forests. In the Amazon region, palms have been used and managed by humans for food, material, medicine and other purposes for millennia. It is, however, debated to what extent the structure of modern palm communities reflects long-term human modification. Here, we investigate the complex interplay of ecological and societal factors that influence the distributions of both human-used and non-used palms in western Amazonia. Location: Amazonia. Time period: Present. Major taxa studied: Palms (Arecaceae). Methods: We used Bayesian hierarchical joint species distribution models to predict the distributions and environmental niche dimensi…
La prova privilegiata «sbiadita» e le ambizioni frustrate del contraente a valle.Spunti per una presunzione legale iuris tantum
2023
L'A. esamina criticamente l'orientamente recentemente emerso in giurisprudenza e da ultimo confermato dal Collegio di Coordinaento ABF, secondo cui l'accertamento della violazione concorrenziale, condotto dall'Autorità antimonopolistica competente e cristallizzato in provvedimento divenuto definitivo, non potrebbe comunque valere quale prova privilegiata in relazione a fattispecie contrattuali perfezionate successivamente alla sua emanazione. Nel rilevarne la contraddittorietà con l'interpretazione avallata dalle Sezioni Unite della Cassazione, che vuole i contratti di fideiussione omnibus, a valle di NBU, fulminati da nullità paziale, l'A. argomenta invece l'esistenza nel sistema di una pr…
Anti-Listeria activity of citrus essential oils in a fresh ovine cheese
2023
The aim of this study was to evaluate the anti-Listeria activity of essential oils (EOs) extracted from the peel of lemons, oranges and tangerines in a fresh cheese produced with pasteurized ewe’s milk. Four cheesemaking trials were performed at the pilot plant scale level, including one control production without the addition of EOs and three experimental productions obtained by the addition of 200 μL/L of each EOs to milk. Before the addition of EOs, the milk of all trials was inoculated with 107 CFU/mL of the starter cultures (Lactococcus lactis NT1 and NT5) and 104 CFU/mL of pathogenic bacteria (Listeria monocytogenes ATCC19114). Plate counts confirmed the dominance of the starter cultu…
Multi-proxy crossdating extends the longest high-elevation tree-ring chronology from the Mediterranean
2023
Hospital Reform in Palermo
2023
A partire dal XV secolo, l'ospedale cessa di essere un riflesso della carità cristiana e diventa un veicolo per la gestione del bene comune. In precedenza, la diffusione della spiritualità influenzata dagli Ordini mendicanti aveva stimolato nuove forme di pietà e opere di carità più ampie, tra cui le visite ai malati, la gestione degli ospedali e la distribuzione di cibo e vestiario. Il tardo Medioevo vide un un cambiamento radicale. Gli ospedali divennero centri polifunzionali dedicati a vari tipi di cure. In linea con una tendenza osservata in tutta Europa, le principali città siciliane (Messina, Catania, Palermo, Siracusa e Trapani) adattarono i propri sistemi ospedalieri alle esigenze d…
Suomalaisen ruokajärjestelmän resilienssi, kriisit ja uusiutuminen
2023
Resilientti ruokajärjestelmä kykenee turvaamaan jatkuvasti ravitsemuksen siitä riippuvaisille ihmisille. Tarkastelemme tutkimuksessamme Suomen ruokajärjestelmän kehitysdynamiikkaa resilienssin näkökulmasta aikavälillä 1334–2022. Tunnistimme analyysissä kuusi regiimiä: laajentumisregiimi, edistysregiimi, karjatalousregiimi, esimoderni regiimi, modernisaatioregiimi ja globalisaatioregiimi. Regiimit ovat olleet polkuriippuvaisia ja vaihtuneet vain kriisien myötä, mutta samalla kriisit ovat johtaneet järjestelmän resilienssin menetykseen eri mittakaavoissa. Kussakin regiimissä ovat toistuneet uudelleenorganisoitumisen, kasvun, kangistumisen ja purkautumisen vaiheet. Kukin regiimi on vuorollaan …
Francesco Crispi le riforme amministrative. Il primo intervento di riforma strutturale dello Stato unitario
2023
Questo contributo analizza il rapporto tra le riforme propugnate dai Governi guidati da Francesco Crispi (ben quattro, tra il 1887 ed il 1891 e tra il 1894 ed 1896) ed il loro artefice, con uno sguardo d’insieme sul complesso processo di modernizzazione dell’Italia che si affacciava al “secolo breve” con un’organizzazione amministrativa arcaica. Partendo dalla formazione giuridica dello statista siciliano, dagli scritti giovanili, dall’attività professionale, dalla cultura risorgimentale e costituzionale che ne forgiarono la personalità e poi dall’attività rivoluzionaria e parlamentare, lo studio perlustra il variegato contesto nel quale proruppe quell’“impeto riformatore dell’amministrazio…
Raccontare e raccontarsi al di là dei "limiti": "Ṣamt al-nawāqīs" di Fatḥiyya Dabiš
2023
Fatḥiyya Dabiš is a Tunisian novelist, poet, short story writer, translator and literary critic who was born in Mareth in 1969. She is best known for her debut novel, entitled “Mīlānīn” (Melanin) and published in 2019, which won the 6th edition (2020) of the prestigious “Katara Prize for Arabic Novel” (Ğā’izat Katārā li’l-riwāya al-‘arabiyya) in the category “Published Novels” (Fi’at al-riwāyāt al-manšūra). The present article focuses on her collection “Ṣamt al-nawāqīs” (The Silence of the Bells), which is a hybrid narrative work (mağmū‘a qiṣaṣiyya sardiyya hağīna) published in 2018. As the writer clarifies in the Introduction, it is not simply a short story collection but rather a selectio…
StateOS : A Memory-Efficient Hybrid Operating System for IoT Devices
2023
The increasing significance of operating systems (OSs) in the development of the internet of things (IoT) has emerged in the last decade. An event-driven OS is memory efficient and suitable for resource-constrained IoT devices and wireless sensors, although the program’s control flow, which is determined by events, is not always obvious. A multithreaded OS with sequential control flow is often considered clearer. However, this approach is memory-consuming. A hybrid OS seeks to combine the strengths of the event-driven approach with multithreaded approach. An event-driven cooperative threaded OS represents a hybrid approach that supports concurrency by explicitly yielding control to another …
Private health insurance in the universal public healthcare system: The role of healthcare provision in Finland
2023
Voluntary private health insurance (VPHI) has gained popularity in universal public healthcare systems. We studied how the local provision of healthcare services correlated with VPHI take-up in Finland. Nationwide register data from a Finnish insurance company was aggregated to the local level and augmented with high-quality data on public and private primary care providers’ geographical closeness and fees. We found that the sociodemographic characteristics explained the VPHI take-up more than public or private healthcare provision. The VPHI take-up was negatively associated with distance to the nearest private clinic, while the associations with distance to public health stations were stat…