showing 36 of ~574560 from 574555 documents
Testing & Opening in Augustusburg A Success Story?
2021
AbstractThe city of Augustusburg allowed for opening of, inter alia, restaurants and hotels joint with large-scale testing. We evaluate this testing & opening (T&O) experiment by comparing the evolution of case rates in Augustusburg with the evolution in other communities of Saxony. We have access to small-scale SARS-CoV-2 infection data at the community level (” Gemeinde”) instead of the county level (” Landkreis”) usually used for disease surveillance. Despite data challenges, we conclude that T&O did not lead to any increase in case rates in Augustusburg compared to its control county. When we measure the effect of T&O on cumulative cases, we find a small increase in Augu…
ω-Alkenylallylboronates: Design, Synthesis, and Application to the Asymmetric Allylation/RCM Tandem Sequence
2021
P. B. thanks the Spanish MINECO for a Ramón y Cajal contract (RyC-2016-20951). M.N.G. thanks the University of Bath for financial support.
Reduced Temperature Sensitivity of Maximum Latewood Density Formation in High-Elevation Corsican Pines under Recent Warming
2021
Maximum latewood density (MXD) measurements from long-lived Black pines (Pinus nigra spp. laricio) growing at the upper treeline in Corsica are one of the few archives to reconstruct southern European summer temperatures at annual resolution back into medieval times. Here, we present a compilation of five MXD chronologies from Corsican pines that contain high-to-low frequency variability between 1168 and 2016 CE and correlate significantly (p <
Computing the original eBWT faster, simpler, and with less memory
2021
Mantaci et al. [TCS 2007] defined the eBWT to extend the definition of the BWT to a collection of strings, however, since this introduction, it has been used more generally to describe any BWT of a collection of strings and the fundamental property of the original definition (i.e., the independence from the input order) is frequently disregarded. In this paper, we propose a simple linear-time algorithm for the construction of the original eBWT, which does not require the preprocessing of Bannai et al. [CPM 2021]. As a byproduct, we obtain the first linear-time algorithm for computing the BWT of a single string that uses neither an end-of-string symbol nor Lyndon rotations. We combine our ne…
Ocena współczesnej kultury Zachodu w nauczaniu Benedykta XVI (Josepha Ratzingera)
2021
The Assessment of the Contemporary Western Culture in the Teaching of Benedict XVI (Joseph Ratzinger)
 The article consists of two parts. In the first one, the authors pointed out an argument in the social sciences concerning ability to reasonably use the „culture” concept in scientific discourse. In the second one, they analyzed opinions Benedict XVI ( Joseph Ratzinger) expressed about present condition of the Western culture. Views of this figure were selected to study due to recognizing significant influential role the Pope plays in the public sphere. In the opinion of Benedict XVI, today there are two cultures of the West that coexist: rational Christian culture and Enlightenment (…
Diethyl [(2,5-diiodo-4-methylphenyl)methyl]phosphonate
2021
The title compound, C12H17I2O3P, was prepared in three steps from p-xylene. Heterodimers between nearly identical molecules are connected via three hydrogen bonds from benzylic and ester methylene groups to phosphonate. The dimers form chains along the a-axis direction, stabilized by C—H...O bridges.
High Pressure Processing Impact on Alternariol and Aflatoxins of Grape Juice and Fruit Juice-Milk Based Beverages.
2021
High-pressure processing (HPP) has emerged over the last 2 decades as a good alternative to traditional thermal treatment for food safety and shelf-life extension, supplying foods with similar characteristics to those of fresh products. Currently, HPP has also been proposed as a useful tool to reduce food contaminants, such as pesticides and mycotoxins. The aim of the present study is to explore the effect of HPP technology at 600 MPa during 5 min at room temperature on alternariol (AOH) and aflatoxin B1 (AFB1) mycotoxins reduction in different juice models. The effect of HPP has also been compared with a thermal treatment performed at 90 °C during 21 s. For this, different juice models, or…
Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnos…
2021
Exhaled breath analysis for early disease detection may provide a convenient method for painless and non-invasive diagnosis. In this work, a novel, compact and easy-to-use breath analyzer platform with a modular sensing chamber and direct breath sampling unit is presented. The developed analyzer system comprises a compact, low volume, temperature-controlled sensing chamber in three modules that can host any type of resistive gas sensor arrays. Furthermore, in this study three modular breath analyzers are explicitly tested for reproducibility in a real-life breath analysis experiment with several calibration transfer (CT) techniques using transfer samples from the experiment. The experiment …
Updated description and distribution of the Patagonian moss Ulota macrodontia Dusén ex Malta (Orthotrichaceae)
2021
Ulota macrodontia Dusen ex Malta is an Andean-Patagonian epiphytic moss that has been misunderstood in recent times (Garilleti et al. 2016). This may be due partly to the fact that it is a rarely c...
The ideal duplication
2021
AbstractIn this paper we present and study the ideal duplication, a new construction within the class of the relative ideals of a numerical semigroup S, that, under specific assumptions, produces a relative ideal of the numerical duplication $$S\bowtie ^b E$$ S ⋈ b E . We prove that every relative ideal of the numerical duplication can be uniquely written as the ideal duplication of two relative ideals of S; this allows us to better understand how the basic operations of the class of the relative ideals of $$S\bowtie ^b E$$ S ⋈ b E work. In particular, we characterize the ideals E such that $$S\bowtie ^b E$$ S ⋈ b E is nearly Gorenstein.
Analysis of clickstream data with mixture hidden markov models
2021
clickstream data sono un’importante fonte di informazioni per l’ecommerce, sebbene non siano semplici da gestire e convertire queste informazioni in un reale vantaggio competitivo non e un compito banale. In questo articolo, consid- ` eriamo l’applicazione dei mixture hidden Markov model a dati relativi al flusso di clickstream estratti dal portale e-commerce di un’azienda di servizi turistici. Sono stati individuati cluster relativi al comportamento di navigazione degli utenti e alla loro posizione geografica che forniscono indicazioni importanti per lo sviluppo di nuove strategie di business. Clickstream data is an important source of information for businesses, however it is not easy to …
Des données ouvertes sur la décomposition des litières végétales dans les sols selon divers contextes agronomiques et pédoclimatiques
2021
International audience
Social Entrepreneurship from a Chronological Approach: A Path for Change
2021
From COVID-19 to future electrification: Assessing traffic impacts on air quality by a machine-learning model
2021
The large fluctuations in traffic during the COVID-19 pandemic provide an unparalleled opportunity to assess vehicle emission control efficacy. Here we develop a random-forest regression model, based on the large volume of real-time observational data during COVID-19, to predict surface-level NO(2), O(3), and fine particle concentration in the Los Angeles megacity. Our model exhibits high fidelity in reproducing pollutant concentrations in the Los Angeles Basin and identifies major factors controlling each species. During the strictest lockdown period, traffic reduction led to decreases in NO(2) and particulate matter with aerodynamic diameters <2.5 μm by –30.1% and –17.5%, respectively, bu…
Trends in marine survival of Atlantic salmon populations in eastern Canada
2021
Abstract Declines in wild Atlantic salmon (Salmo salar) abundance throughout the north Atlantic are primarily attributed to decreases in survival at sea. However, comparing trends in marine survival among populations is challenging as data on both migrating smolts and returning adults are sparse and models are difficult to parameterize due to their varied life histories. We fit a hierarchical Bayesian maturity schedule model to data from seven populations in eastern Canada to estimate numbers of out-migrating smolts, survival in the first and second year at sea, and the proportion returning after 1 year. Trends in survival at sea were not consistent among populations; we observe positive, n…
Re-evaluation and typification of Foeniculum piperitum (Apiaceae), an underknown medicinal plant and crop wild relative
2021
Foeniculum piperitum was described as Anethum piperitum based on plants collected in Sicily, Italy. Currently it is treated either as a synonym of Foeniculum vulgare, or as one of two subspecies within that taxon. Here we show that F. vulgare and F. piperitum are two different, sometimes co-occurring, taxa and that given clear morphological and ecological separation, they should be treated as distinct species. Anethum piperitum is typified. Owing to misapplication of names and wrong synonymizations, the ecology and chorology of F. vulgare and F. piperitum have to be better defined.
Electrochemical Installation of CFH 2 −, CF 2 H−, CF 3 −, and Perfluoroalkyl Groups into Small Organic Molecules
2021
Electrosynthesis can be considered a powerful and sustainable methodology for the synthesis of small organic molecules. Due to its intrinsic ability to generate highly reactive species under mild conditions by anodic oxidation or cathodic reduction, electrosynthesis is particularly interesting for otherwise challenging transformations. One such challenge is the installation of fluorinated alkyl groups, which has gained significant attention in medicinal chemistry and material science due to their unique physicochemical features. Unsurprisingly, several electrochemical fluoroalkylation methods have been established. In this review, we survey recent developments and established methods in the…
Weed dynamic in Conservation Agriculture: experiences from the Isite-BFC regional network of farmers and cropping system experiments on agroecology i…
2021
ISBN: 978-84-09-37744-2; International audience; Conservation Agriculture (CA) relies on three fundamental pillars: diversified crop rotation, permanent soil coverand no soil disturbance. Weed control relies on few tools because pre-sowing tillage, pre-emergence herbicidespraying and in-crop mechanical weeding are not possible. This could lead to drastic changes in weed communitiesand quickly after the transition to CA, with fewer annual species (weed seeds remain on the soil surface, a conditiondeemed to be unfavourable to weed germination) and higher perennial species. However, the implementation ofCA principles could be transcribed into a wide array of cropping systems because the object…
The last-mile vehicle routing problem with delivery options
2021
AbstractThe ongoing rise in e-commerce comes along with an increasing number of first-time delivery failures due to the absence of the customer at the delivery location. Failed deliveries result in rework which in turn has a large impact on the carriers’ delivery cost. In the classical vehicle routing problem (VRP) with time windows, each customer request has only one location and one time window describing where and when shipments need to be delivered. In contrast, we introduce and analyze the vehicle routing problem with delivery options (VRPDO), in which some requests can be shipped to alternative locations with possibly different time windows. Furthermore, customers may prefer some deli…
Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease
2021
Platelets are the main players in thrombotic diseases, where activated platelets not only mediate thrombus formation but also are involved in multiple interactions with vascular cells, inflammatory components, and the coagulation system. Although in vitro reactivity of platelets provides information on the function of circulating platelets, it is not a full reflection of the in vivo activation state, which may be relevant for thrombotic risk assessment in various disease conditions. Therefore, studying release markers of activated platelets in plasma is of interest. While this type of study has been done for decades, there are several new discoveries that highlight the need for a critical a…
Arte, género y diseño en educación digital
2021
Supervised Analysis for Phenotype Identification: The Case of Heart Failure Ejection Fraction Class
2021
Artificial Intelligence is creating a paradigm shift in health care, with phenotyping patients through clustering techniques being one of the areas of interest. Objective: To develop a predictive model to classify heart failure (HF) patients according to their left ventricular ejection fraction (LVEF), by using available data from Electronic Health Records (EHR). Subjects and methods: 2854 subjects over 25 years old with a diagnosis of HF and LVEF, measured by echocardiography, were selected to develop an algorithm to predict patients with reduced EF using supervised analysis. The performance of the developed algorithm was tested in heart failure patients from Primary Care. To select the mo…
Interferometric Phase Retrieval in Optical Transient Detection
2021
A transient detection imaging system (TDI), also known as optical novelty filter, is an adaptive interferometric device that detects temporal changes in a scene while suppressing its static parts. Removal of background improves contrast and helps visualizing and measuring intensity and phase. Following the first TDI proposal by Cudney et al. [1] , most TDI systems are based on photorefractive two-wave mixing [2] . Previous works rely on conventional intensity measurements, where partial information about input signal phase changes are obtained by previous calibration using an input phase-output intensity transfer function of the particular system.
“It’s hard to keep a distance when you’re with someone you really care about” — a qualitative study of adolescents’ pandemic-related health literacy …
2021
AbstractPurposeThe aim of this study was to explore how adolescents accessed, understood, appraised, and applied information on pandemic preventive measures, how their lives were impacted by long-lasting regulations and how they described their quality of life.MethodsA qualitative design with focus group interviews was used to elaborate on the quantitative survey results obtained and analyzed in a previous survey study from the first phase of the Covid-19 pandemic. Five focus groups with seventeen adolescents were conducted digitally during the second pandemic phase in November and December 2020. The interview data were analyzed with directed content analysis.ResultsThe adolescents reported…
Allogeneic hematopoietic cell transplantation in older myelofibrosis patients: A study of the chronic malignancies working party of EBMT and the Span…
2021
Allogeneic hematopoietic cell transplantation (allo-HCT) is increasingly used in older myelofibrosis (MF) patients, but its risk/benefit ratio compared to non-transplant approaches has not been evaluated in this population. We analyzed the outcomes of allo-HCT in 556 MF patients aged > 65years from the EBMT registry, and determined the excess mortality over the matched general population of MF patients > 65years managed with allo-HCT (n=556) or conventional drug treatment (n=176). The non-transplant cohort included patients with intermediate-2 or high risk DIPSS from the Spanish Myelofibrosis Registry. After a median follow-up of 3.4years, the estimated 5-year survival rate, non-relapse mor…
CONGENITAL NEUROBLASTOMA: A RARE CASE OF PLURIVISCERAL METASTATIC DISSEMINATION
2021
Neuroblastoma is one of the most common neonatal tumors. It involves children in early infancy and originates from neural crest cells of the adrenal gland medulla or sympathetic glia. We report an unusual case of congenital poorly differentiated neuroblastoma with multiple metastases in the brain and cerebellum. The biophysical profile showed a prominent polyhydramnios at 25.3 weeks of gestation; meantime, the mother was diagnosed with gestational diabetes. The mass was detected during the third ultrasonographic examination at 31.4 weeks of gestation. The fetus lived only one day after birth and the postmortem examinations were performed subsequently. An autopsy was performed both to unders…
Sul testo del settimo libro di Quinto Smirneo
2021
This paper aims to examine the text of the seventh book of Quintus Smyrnaeus’ Posthomerica, the object of a recent commentary by G. P. Tsomis. Particular attention will be paid to problems concerning textual criticism and exegesis, contained in the book, which recounts the events connected with Neoptolemus’ intervention in the Trojan War. An issue concerning the narrative structure and technique will also be addressed: the poet appears to intentionally imitate Homer not only from a linguistic and lexical point of view, but also in the handling of contemporary events, in which connection Zielinski’s law may be seen as applying to Quintus’ work.
Implementation of a STEAM project in compulsory secondary education that creates connections with the environment (Implementación de un proyecto STEA…
2021
The teaching of STEAM has been gaining ground in the world of education for some years now. This article presents two fundamental contributions to STEAM literature. The first contribution is the de...
Micro-RNAs miR-375-3p and miR-7-5p are released alongside ACTH from corticotroph pituitary neuroendocrine tumor
2021
AbstractObjectiveCirculating miRNAs are found in bodily fluids including plasma and can serve as biomarkers for diseases. The aim of this study was to provide the first insight into the landscape of circulating miRNAs in close proximity to the adrenocorticotropic hormone (ACTH) secreting PitNET. To achieve this objective next-generation sequencing of miRNAs in plasma from bilateral inferior petrosal sinus sampling (BIPSS) - a gold standard in diagnosing ACTH-secreting PitNETs, was carried out.MethodsSinistral (left) and dextral (right) BIPSS blood samples of the patient were collected in three time points: before the administration of corticotropin-releasing hormone, 5 and 15 minutes after …
The Four Axes of Palermo’s Commerce: a Geographical Perspective
2021
Le dinamiche commerciali all’interno della città rappresentano un ottimo punto di osservazione per studiare i processi di trasformazione urbana. Queste dinamiche riflettono verticalità e orizzontalità dei sistemi di relazione, nonché scambi e reciprocità dei rapporti socio-economici e culturali. Da una prospettiva geografica è di grande interesse individuare permanenze e mutazioni culturali, sociali, economi- che che costituiscono il tessuto cittadino e danno forma all’attualità. Questo contributo nasce nell’ambito del Progetto di Rilevante Interesse Nazionale (PRIN) 2015 “Commercio, consumo e città: pratiche, pianificazione e governance per l’inclusione, la resilienza e la sostenibilità ur…
Intersektionaaliset toverit : Jodi Deanin poliittisesta ajattelusta
2021
New sedimentological and stratigraphical data on the Permian and Triassic in northeastern Utah, USA
2021
International audience; We present the Permian to Triassic sedimentological evolution in the Vernal area, northeastern Utah, todetermine: (1) the magnitude of the Permian-Triassic (P-T) unconformity, (2) the depositional environmentsabove the unconformity, as well as (3) their evolution in space and time. Within this area, Permian depositsconsists of the Weber Sandstone, which represents aeolian deposits, overlain by the Park City Formation,composed of silty and sandy marine limestones, dolomites and phosphatic shales. In some places, anunconformity is observed at the top of the Weber Sandstone, which is directly overlain by the MoenkopiGroup. This formation is mostly composed of siltstone,…
Are we confident that final‐year medical students know at least basics about diabetes?: A preliminary report from the multicenter, survey‐based Diabe…
2021
Abstract Background We present the results of the pilot study of a multinational “Diabetes Know‐Me” project investigating knowledge regarding diabetes of medical students. This is the first collaborative project of the ISPAD JENIOUS group. Methods Students of the final year of medical studies from six countries answered a 25‐question survey regarding basic knowledge concerning diabetes (1091 surveys handed out, response rate 86%). Results Among the responders (58% female) 90% confirmed attending diabetology classes; 11% planned to specialize in diabetology. There were significant differences between countries in the median score of correct answers ranging from 10/25 to 22/25. Attending diab…
Profiles of multidrug-resistant organisms among patients with bacteremia in intensive care units: an international ID-IRI survey
2021
Evaluating trends in antibiotic resistance is a requisite. The study aimed to analyze the profile of multidrug-resistant organisms (MDROs) among hospitalized patients with bacteremia in intensive care units (ICUs) in a large geographical area. This is a 1-month cross-sectional survey for blood-borne pathogens in 57 ICUs from 24 countries with different income levels: lower-middle-income (LMI), upper-middle-income (UMI), and high-income (HI) countries. Multidrug-resistant (MDR), extensively drug-resistant (XDR), or pan-drug-resistant isolates were searched. Logistic regression analysis determined resistance predictors among MDROs. Community-acquired infections were comparable to hospital-acq…
General measurement technique of the ratio between chromatic dispersion and the nonlinear coefficient
2021
Measuring the nonlinear coefficient γ of any guiding medium, regardless of the sign and magnitude of its group-velocity dispersion parameter β 2 , is challenging because of the lack of general solutions of the nonlinear Schrodinger equation (NLSE). Indeed, existing approaches typically need to disregard chromatic-dispersion effects to determine γ [1] . Here we propose an all-encompassing approach to measure the ratio β 2 /γ and prove our method in polarization-maintaining (PM) and single-mode (SM) fibers with positive and negative β 2 .
Prácticas culturales y espacios públicos como lugares de interacción social y política. Un análisis de activismo y de crítica festiva en Barcelona y …
2021
espanolEl desarrollo de las grandes ciudades se ha constituido como un fenomeno global, reduciendo las posibilidades de generar convivencia en el espacio social. La busqueda actual por conectar la escala micropolitica de estos espacios con sus habitantes reconfigura el sentido de pertenencia a la ciudad. Esta aspiracion, muchas veces, desemboca en formas activas de desobediencia social en el espacio publico o, por contraposicion, de acciones que perpetuan la reproduccion de practicas culturales conservadoras. Desde esta mirada el presente trabajo se propone analizar algunas practicas culturales que ubican la participacion en el espacio publico como protagonista. Por un lado, acciones artivi…