0000000000023740
AUTHOR
Wei Wang
Measurement of the Soft-Drop Jet Mass in pp Collisions at s=13 TeV with the ATLAS Detector
Jet substructure observables have significantly extended the search program for physics beyond the standard model at the Large Hadron Collider. The state-of-the-art tools have been motivated by the ...
Search for pairs of highly collimated photon-jets in pp collisions at s=13 TeV with the ATLAS detector
Results of a search for the pair production of photon-jets - collimated groupings of photons - in the ATLAS detector at the Large Hadron Collider are reported. Highly collimated photon-jets can arise from the decay of new, highly boosted particles that can decay to multiple photons collimated enough to be identified in the electromagnetic calorimeter as a single, photonlike energy cluster. Data from proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 36.7 fb-1, were collected in 2015 and 2016. Candidate photon-jet pair production events are selected from those containing two reconstructed photons using a set of identification criteria …
Observation of light-by-light scattering in ultraperipheral Pb+Pb collisions with the ATLAS detector
This Letter describes the observation of the light-by-light scattering process, γγ→γγ, in Pb+Pb collisions at √sNN=5.02 TeV. The analysis is conducted using a data sample corresponding to an integrated luminosity of 1.73 nb−1, collected in November 2018 by the ATLAS experiment at the LHC. Light-by-light scattering candidates are selected in events with two photons produced exclusively, each with transverse energy EγT>3 GeV and pseudorapidity |ηγ|<2.4, diphoton invariant mass above 6 GeV, and small diphoton transverse momentum and acoplanarity. After applying all selection criteria, 59 candidate events are observed for a background expectation of 12±3 events. The observed excess of events…
Search for squarks and gluinos in final states with jets and missing transverse momentum using 36 fb−1 of s=13 TeV pp collision data with the ATLAS detector
A search for the supersymmetric partners of quarks and gluons (squarks and gluinos) in final states containing hadronic jets and missing transverse momentum, but no electrons or muons, is presented ...
Comparison of Fragmentation Functions for Jets Dominated by Light Quarks and Gluons from pp and Pb+Pb Collisions in ATLAS
Charged-particle fragmentation functions for jets azimuthally balanced by a high-transverse-momentum, prompt, isolated photon are measured in 25 pb^{-1} of pp and 0.49 nb^{-1} of Pb+Pb collision data at 5.02 TeV per nucleon pair recorded with the ATLAS detector at the Large Hadron Collider. The measurements are compared to predictions of Monte Carlo generators and to measurements of inclusively selected jets. In pp collisions, a different jet fragmentation function in photon-tagged events from that in inclusive jet events arises from the difference in fragmentation between light quarks and gluons. The ratios of the fragmentation functions in Pb+Pb events to that in pp events are used to e…
Dijet azimuthal correlations and conditional yields in pp and p+Pb collisions at sNN=5.02TeV with the ATLAS detector
This paper presents a measurement of forward-forward and forward-central dijet azimuthal angular correlations and conditional yields in proton-proton (pp) and proton-lead (p + Pb) collisions as a p ...
Probing the Quantum Interference between Singly and Doubly Resonant Top-Quark Production in pp Collisions at s=13 TeV with the ATLAS Detector
This Letter presents a normalized differential cross-section measurement in a fiducial phase-space region where interference effects between top-quark pair production and associated production of a single top quark with a W boson and a b-quark are significant. Events with exactly two leptons (ee, μμ, or eμ) and two b-tagged jets that satisfy a multiparticle invariant mass requirement are selected from 36.1 fb^{-1} of proton-proton collision data taken at sqrt[s]=13 TeV with the ATLAS detector at the LHC in 2015 and 2016. The results are compared with predictions from simulations using various strategies for the interference. The standard prescriptions for interference modeling are signifi…
Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages.
Phenolic acids are found in natural plants, such as caffeic acid, rosmarinic acid, and chlorogenic acid. They have long been used as pharmacological actives, owing to their anti-inflammatory and antioxidant activities. Cryptochlorogenic acid (CCGA) is a special isomer of chlorogenic acid; the pharmacological effects and related molecular mechanisms of CCGA have been poorly reported. In the present study, the antioxidant and anti-inflammatory effects of CCGA in RAW 264.7 macrophages and the underlying mechanisms were investigated. The results revealed that CCGA dose-dependently inhibited LPS-induced production of NO, TNF-α, and IL-6 and blocked iNOS, COX-2, TNF-α, and IL-6 expressions. CCGA …
Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway.
Cajaninstilbene acid (CSA), an active compound separated from pigeon pea leaves, possesses the highly efficient antioxidant activities. Transcription factor nuclear factor-erythroid 2-related factor 2 (Nrf2) is an important regulator of cellular oxidative stress. This study examined the role of Nrf2 in CSA-mediated antioxidant effects on human hepatocarcinoma (HepG2) cell line. The generation of reactive oxygen species (ROS) upon H2O2 and CSA treatment was lower than that of H2O2 alone. CSA activated Nrf2 as evaluated by Western blotting. A luciferase reporter assay also demonstrated that CSA-activated signaling resulted in the increased transcriptional activity of Nrf2 through binding to t…
Distributed Adaptive Control for Asymptotically Consensus Tracking of Uncertain Nonlinear Systems With Intermittent Actuator Faults and Directed Communication Topology
In this article, we investigate the output consensus tracking problem for a class of high-order nonlinear systems with unknown parameters, uncertain external disturbances, and intermittent actuator faults. Under the directed topology conditions, a novel distributed adaptive controller is proposed. The common time-varying trajectory is allowed to be totally unknown by part of subsystems. Therefore, the assumption on the linearly parameterized trajectory signal in most literature is no longer needed. To achieve the relaxation, extra distributed parameter estimators are introduced in all subsystems. Besides, to handle the actuator faults occurring at possibly infinite times, a new adaptive com…
Search for high-mass dilepton resonances using 139 fb−1 of pp collision data collected at s=13 TeV with the ATLAS detector
A search for high-mass dielectron and dimuon resonances in the mass range of 250 GeV to 6 TeV is presented. The data were recorded by the ATLAS experiment in proton–proton collisions at a centre-of-mass energy of s=13 TeV during Run 2 of the Large Hadron Collider and correspond to an integrated luminosity of 139 fb −1 . A functional form is fitted to the dilepton invariant-mass distribution to model the contribution from background processes, and a generic signal shape is used to determine the significance of observed deviations from this background estimate. No significant deviation is observed and upper limits are placed at the 95% confidence level on the fiducial cross-section times bran…
Search for dark matter in association with a Higgs boson decaying to two photons at s=13 TeV with the ATLAS detector
A search for dark matter in association with a Higgs boson decaying to two photons is presented. This study is based on data collected with the ATLAS detector, corresponding to an integrated lumino ...
Search for flavor-changing neutral currents in top quark decays t→Hc and t→Hu in multilepton final states in proton-proton collisions at s=13 TeV with the ATLAS detector
Flavor-changing neutral currents are not present in the Standard Model at tree level and are suppressed in loop processes by the unitarity of the Cabibbo-Kobayashi-Maskawa matrix; the corresponding ...
Search for long-lived particles produced in pp collisions at s=13 TeV that decay into displaced hadronic jets in the ATLAS muon spectrometer
A search for the decay of neutral, weakly interacting, long-lived particles using data collected by the ATLAS detector at the LHC is presented. The analysis in this paper uses 36.1 fb(-1) of proton ...
Properties of jet fragmentation using charged particles measured with the ATLAS detector in pp collisions at s=13 TeV
This paper presents a measurement of quantities related to the formation of jets from high-energy quarks and gluons (fragmentation). Jets with transverse momentum 100 GeV 500 MeV and vertical bar ...
Search for Higgs Boson Decays into a Z Boson and a Light Hadronically Decaying Resonance Using 13 TeV pp Collision Data from the ATLAS Detector
A search for Higgs boson decays into a Z boson and a light resonance in two-lepton plus jet events is performed, using a pp collision dataset with an integrated luminosity of 139 fb^{-1} collected at sqrt[s]=13 TeV by the ATLAS experiment at the CERN LHC. The resonance considered is a light boson with a mass below 4 GeV from a possible extended scalar sector or a charmonium state. Multivariate discriminants are used for the event selection and for evaluating the mass of the light resonance. No excess of events above the expected background is found. Observed (expected) 95% confidence-level upper limits are set on the Higgs boson production cross section times branching fraction to a Z bos…
Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells
Pinolenic acid (PLA), a natural compound isolated from pine nut oil, has been reported to exert bioactivity against lipid anabolism. Nonetheless, the underlying mechanisms still poorly elucidated. The aim of this study is to comprehensively demonstrate the effects of PLA on oleic acid (OA)-induced non-alcoholic fatty liver disease (NAFLD) and their relationship with the lipid metabolic regulation. The results demonstrated that treatment with PLA dramatically inhibited lipid accumulation, oxidative stress as well as inflammatory responses induced by oleic acid in HepG2 cells. PLA also obviously decreased the levels of cellular triglyceride (TG), total cholesterol (TC), malondialdehyde (MDA),…
Measurement of jet fragmentation in Pb+Pb and pp collisions at sNN=5.02 TeV with the ATLAS detector
This paper presents a measurement of jet fragmentation functions in 0.49 nb−1 of Pb+Pb collisions and 25 pb−1 of pp collisions at √sNN=5.02 TeV collected in 2015 with the ATLAS detector at the LHC. These measurements provide insight into the jet quenching process in the quark-gluon plasma created in the aftermath of ultrarelativistic collisions between two nuclei. The modifications to the jet fragmentation functions are quantified by dividing the measurements in Pb+Pb collisions by baseline measurements in pp collisions. This ratio is studied as a function of the transverse momentum of the jet, the jet rapidity, and the centrality of the collision. In both collision systems, the jet fragmen…
Search for a Structure in the Bs0π± Invariant Mass Spectrum with the ATLAS Experiment
A search for the narrow structure, X(5568), reported by the D0 Collaboration in the decay sequence X→B_{s}^{0}π^{±}, B_{s}^{0}→J/ψϕ, is presented. The analysis is based on a data sample recorded with the ATLAS detector at the LHC corresponding to 4.9 fb^{-1} of pp collisions at 7 TeV and 19.5 fb^{-1} at 8 TeV. No significant signal was found. Upper limits on the number of signal events, with properties corresponding to those reported by D0, and on the X production rate relative to B_{s}^{0} mesons, ρ_{X}, were determined at 95% confidence level. The results are N(X)<382 and ρ_{X}<0.015 for B_{s}^{0} mesons with transverse momenta above 10 GeV, and N(X)<356 and ρ_{X}<0.016 for transverse m…
Study on the characteristics of electromagnetic noise of axial flux permanent magnet synchronous motor
Published version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2014/764105 Open Access The normal electromagnetic force distribution in stator system of axial flux permanent magnet synchronous motor (PMSM) has been thoroughly analyzed in this paper. The main composition of force wave causing vibration and noise has been proposed, and at the same time a calculation method of stator natural frequency of axial flux PMSM has been raised. Through this method electromagnetic force wave, natural frequency, vibration response, and electromagnetic noise of a 15 kW axial flux PMSM with 22 poles and 24 slots have been calc…
Study of the hard double-parton scattering contribution to inclusive four-lepton production in pp collisions at s=8 TeV with the ATLAS detector
The inclusive production of four isolated charged leptons in pp collisions is analysed for the presence of hard double-parton scattering, using 20.2 fb(-1) of data recorded in the ATLAS detector at ...
Search for Low-Mass Dijet Resonances Using Trigger-Level Jets with the ATLAS Detector in pp Collisions at s=13 TeV
Searches for dijet resonances with sub-TeV masses using the ATLAS detector at the Large Hadron Collider can be statistically limited by the bandwidth available to inclusive single-jet triggers, who ...
Activity of the antiestrogenic cajanin stilbene acid towards breast cancer
Antiestrogenic therapy is a mainstay for estrogen receptor (ERα)-positive breast cancer. Due to the development of resistance to established antihormones such as tamoxifen, novel compounds are required. The low abundant cajanin stilbene acid (CSA) recently isolated by us from Pigeon Pea (Cajanus cajan) has structural similarities with estrogen. We analyzed the cytotoxic and anticancer activity of CSA in ERα-positive and -negative human breast cancer cells in vitro, in vivo and in silico. CSA exerts anticancer and antiestrogenic activities towards ERα-positive breast cancer, and it showed cytotoxicity towards tamoxifen-resistant MCF-7 cells, implying that CSA may be active against tamoxifen-…
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies
Contains fulltext : 252214.pdf (Publisher’s version ) (Open Access) BACKGROUND: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies. METHODS: In this pooled analysis we harmonised individual patient data from the ERICC, LUNG SAFE, PRoVENT, and PRoVENT-iMiC prospective observational studies, which were conducted from June, 2011, to December, 2018, in 534 ICUs in 54 countries. We used the 2016 World Bank classification to defi…
In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus alba L. Leaves, Stems and Fruits
In this study, the aqueous and ethanolic extracts (leaves, stems and fruits) from Morus alba L., a traditional Chinese medicine, were evaluated for their antioxidant and antimicrobial properties. Ethanolic extracts showed higher contents of both total phenolics and flavonoids than aqueous extracts. The total phenolic content was in the order of: leaf extracts > fruit extracts > stem extracts, whereas the total flavonoids was: leaf extracts > stem extracts > fruit extracts. Using DPPH assays, the concentrations providing 50% inhibition (IC50) values of aqueous extracts from leaves, stems and fruits were 7.11 ± 1.45 mg/ml, 86.78 ± 3.21 mg/ml and 14.38 ± 2.83 mg/ml, respectively, …
Dijet Resonance Search with Weak Supervision Using s=13 TeV pp Collisions in the ATLAS Detector
This Letter describes a search for narrowly resonant new physics using a machine-learning anomaly detection procedure that does not rely on signal simulations for developing the analysis selection. Weakly supervised learning is used to train classifiers directly on data to enhance potential signals. The targeted topology is dijet events and the features used for machine learning are the masses of the two jets. The resulting analysis is essentially a three-dimensional search A→BC, for m_{A}∼O(TeV), m_{B},m_{C}∼O(100 GeV) and B, C are reconstructed as large-radius jets, without paying a penalty associated with a large trials factor in the scan of the masses of the two jets. The full run 2 sq…
Adaptive consensus of uncertain nonlinear systems with event triggered communication and intermittent actuator faults
This paper investigates distributed consensus tracking problem for uncertain nonlinear systems with event-triggered communication. The common desired trajectory information and each subsystem's state will be broadcast to their linked subsystems only when predefined triggering conditions are satisfied. Compared with the existing related literature, the main features of the results presented in this paper include four folds. (i) A totally distributed adaptive control scheme is developed for multiple nonlinear systems without Lipschitz condition, while with parametric uncertainties. (ii) The derivative of desired trajectory function is allowed unknown by all subsystems and directed communicati…
Constraints on off-shell Higgs boson production and the Higgs boson total width in ZZ → 4ℓ and ZZ → 2ℓ2ν final states with the ATLAS detector
A measurement of off-shell Higgs boson production in the and decay channels, where ℓ stands for either an electron or a muon, is performed using data from proton–proton collisions at a centre-of-mass energy of TeV. The data were collected by the ATLAS experiment in 2015 and 2016 at the Large Hadron Collider, and they correspond to an integrated luminosity of . An observed (expected) upper limit on the off-shell Higgs signal strength, defined as the event yield normalised to the Standard Model prediction, of 3.8 (3.4) is obtained at 95% confidence level (CL). Assuming the ratio of the Higgs boson couplings to the Standard Model predictions is independent of the momentum transfer of the Higgs…
Search for pair production of Higgsinos in final states with at least three b -tagged jets in s=13 TeV pp collisions using the ATLAS detector
A search for pair production of the supersymmetric partners of the Higgs boson (higgsinos H˜) in gauge-mediated scenarios is reported. Each higgsino is assumed to decay to a Higgs boson and a gravitino. Two complementary analyses, targeting high- and low-mass signals, are performed to maximize sensitivity. The two analyses utilize LHC pp collision data at a center-of-mass energy s=13 TeV, the former with an integrated luminosity of 36.1 fb-1 and the latter with 24.3 fb-1, collected with the ATLAS detector in 2015 and 2016. The search is performed in events containing missing transverse momentum and several energetic jets, at least three of which must be identified as b-quark jets. No sig…
Adaptive Asymptotically Tracking Control for Uncertain Strict-Feedback Nonlinear Systems with Input Quantization
In this paper, we investigate the output tracking control problem for a class of uncertain nonlinear systems in parametric strict feedback form with quantized input. A novel backstepping based adaptive quantized control scheme is proposed. Different from the existing results, the true quantization parameters are allowed to be unknown in the design of adaptive controller. It is shown that with the proposed control scheme, the system output can track the desired trajectory asymptotically and all the closed-loop signals are globally uniformly bounded.
Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway
Dryofragin is a phloroglucinol derivative extracted from Dryopteris fragrans (L.) Schott. In this study, the anticancer activity of dryofragin on human breast cancer MCF-7 cells was investigated. Dryofragin inhibited the growth of MCF-7 cells in a time and concentration-dependent manner. The cell viability was measured using MTT assay. After treatment with dryofragin for 72, 48 and 24 h, the IC₅₀ values were 27.26, 37.51 and 76.10 μM, respectively. Further analyses of DNA fragmentation and Annexin V-PI double-labeling indicated an induction of apoptosis. Dryofragin-treatment MCF-7 cells had a significantly accumulation of reactive oxygen species (ROS), as well as an increased percentage of …
Resolution of the ATLAS muon spectrometer monitored drift tubes in LHC Run 2
The momentum measurement capability of the ATLAS muon spectrometer relies fundamentally on the intrinsic single-hit spatial resolution of the monitored drift tube precision tracking chambers. Optimal resolution is achieved with a dedicated calibration program that addresses the specific operating conditions of the 354 000 high-pressure drift tubes in the spectrometer. The calibrations consist of a set of timing offsets and drift time to drift distance transfer relations, and result in chamber resolution functions. This paper describes novel algorithms to obtain precision calibrations from data collected by ATLAS in LHC Run 2 and from a gas monitoring chamber, deployed in a dedicated gas fac…
Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway.
Aspidin PB, a phloroglucinol derivative isolated from Dryopteris fragrans (L.) Schott, has been previously reported to exert high biological activities. In the present study, we analyzed the apoptotic mechanisms of aspidin PB on human hepatoma cell line, HepG2. Initially, aspidin PB was shown to inhibit the growth of HepG2 cells in a time and dose-dependent manner. After treatment with aspidin PB for 72 h, 48 h and 24 h using MTT assay, the IC(50) values were 10.59 μM, 20.86 μM and 46.59 μM, respectively. Aspidin PB was capable to induce apoptosis, as measured by mitochondrial membrane potential (ΔΨm), acridine orange (AO) staining and propidium iodide (PI)/annexin V-FITC double staining. T…
Calibration strategy of the JUNO experiment
We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination. [Figure not available: see fulltext.]
Search for trilepton resonances from chargino and neutralino pair production in s=13 TeV pp collisions with the ATLAS detector
A search is performed for the electroweak pair production of charginos and associated production of a chargino and neutralino, each of which decays through an $R$-parity-violating coupling into a lepton and a $W$, $Z$, or Higgs boson. The trilepton invariant-mass spectrum is constructed from events with three or more leptons, targeting chargino decays that include an electron or muon and a leptonically decaying $Z$ boson. The analyzed dataset corresponds to an integrated luminosity of 139 fb$^{-1}$ of proton-proton collision data produced by the Large Hadron Collider at a center-of-mass energy of $\sqrt{s}$ = 13 TeV and collected by the ATLAS experiment between 2015 and 2018. The data are f…
Search for R-parity-violating supersymmetric particles in multi-jet final states produced in p–p collisions at s=13 TeV using the ATLAS detector at the LHC
Results of a search for gluino pair production with subsequent R-parity-violating decays to quarks are presented. This search uses 36.1 fb(-1) of data collected by the ATLAS detector in proton-prot ...
Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway.
Dihydroquercetin (DHQ) is a well-known antioxidant agent. In the present investigation, we reported for the first time that DHQ stimulates the expression of phase II detoxifying enzymes through the Nrf2-dependent signaling pathway. The IC50 values of DHQ for reduction of 2,2-diphenyl-1-picrylhydrazol (DPPH), reducing power assay, lipid peroxidation assay, and xanthine oxidase inhibition were 5.96, 4.31, 2.03, and 13.24 μM, respectively. DHQ possessed considerable protective activity from oxidative DNA damage. A luciferase reporter assay also demonstrated that DHQ-activated signaling resulted in the increased transcriptional activity of Nrf2 through binding to the ARE (antioxidant response e…
Measurement of the nuclear modification factor for inclusive jets in Pb+Pb collisions at sNN=5.02 TeV with the ATLAS detector
Measurements of the yield and nuclear modification factor, R-AA, for inclusive jet production are performed using 0.49 nb(-1) of Pb+Pb data at root s(NN) = 5.02 TeV and 25 pb(-1) of Pb+Pb data at r ...
Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts
Abstract In this study, resin adsorption as a means to enrich rare stilbenes cajaninstilbene acid (CSA) and longistyline C (LLC), and coumarin cajanuslactone (CL) from pigeon pea leaves was investigated. Among widely used twenty macroporous adsorption resins, NKA-9 resin presented higher adsorption capacity and desorption ratio in static tests. The adsorption kinetic model fitted better depended on types of compounds and pH values. The experimental adsorption data were better fitted to Langmuir isotherm (R2 0.921–0.991) than Freundlich isotherm (R2 0.753–0.988). In order to optimize the operating parameters for separating CSA, LLC and CL, dynamic adsorption and desorption tests were carried…
Adaptive control of a class of strict-feedback time-varying nonlinear systems with unknown control coefficients
Abstract In this paper, robust adaptive control of a class of strict-feedback nonlinear systems with unknown control directions is investigated. A novel Nussbaum-type function is developed and a key theorem is drawn which involves quantifying the addition of multiple Nussbaum functions with different control directions in a single inequality. Global stability of the closed-loop system and asymptotic stabilization of system output are proved. A simulation example is given to illustrate the effectiveness of the proposed control scheme.
Characterization of five fungal endophytes producing Cajaninstilbene acid isolated from pigeon pea [Cajanus cajan (L.) Millsp].
Five fungal endophytes (K4, K5, K6, K9, K14) producing Cajaninstilbene acid (CSA, 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid) were isolated from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]. CSA is responsible for the prominent pharmacological activities in pigeon pea. The amount of CSA in culture solution varied among the five fungal endophytes. K4 produced the highest levels of CSA (1037.13 µg/L) among the endophytes tested after incubation for five days. Both morphological characteristics and molecular methods were used for species identification of fungal endophytes. The five endophytic isolates were characterized by analyzing the internal transcribed spacer (ITS) rR…
Intravoxel incoherent motion derived liver perfusion/diffusion readouts can be reliable biomarker for the detection of viral hepatitis B induced liver fibrosis
Background: Recent two studies reported that intravoxel incoherent motion (IVIM) analysis can separate healthy livers and viral hepatitis B (VHB) induced liver fibrosis. However, in these two studies the starting b-value for bi-exponential decay analysis was b =10 and b =15 s/mm 2 respectively. The current study has two primary aims. The first is to further confirm the diagnostic value of IVIM in detecting liver fibrosis. The second is to test whether by sampling very low b-value densely, then b =0 s/mm 2 image could be included to improve IVIM’s diagnostic performance. Methods: This was a prospective study with data acquired at the Third Xiangya Hospital of Central South University, Changs…
Search for Resonant and Nonresonant Higgs Boson Pair Production in the bb¯τ+τ− Decay Channel in pp Collisions at s=13 TeV with the ATLAS Detector
A search for resonant and nonresonant pair production of Higgs bosons in the b (b) over bar tau(+)tau(-) final state is presented. The search uses 36.1 fb(-1) of pp collision data with root s = 13 ...
Search for the Production of a Long-Lived Neutral Particle Decaying within the ATLAS Hadronic Calorimeter in Association with a Z Boson from pp Collisions at s=13 TeV
This Letter presents a search for the production of a long-lived neutral particle (Zd) decaying within the ATLAS hadronic calorimeter, in association with a standard model (SM) Z boson produced via an intermediate scalar boson, where Z→+ (=e, μ). The data used were collected by the ATLAS detector during 2015 and 2016 pp collisions with a center-of-mass energy of s=13 TeV at the Large Hadron Collider and correspond to an integrated luminosity of 36.1±0.8 fb-1. No significant excess of events is observed above the expected background. Limits on the production cross section of the scalar boson times its decay branching fraction into the long-lived neutral particle are derived as a function of …
Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.] and the evaluation of antioxidant activity
Abstract An enzyme pretreatment and negative-pressure cavitation extraction (E-NPCE) method was investigated for extraction genistein and apigenin from pigeon pea roots. The important parameters involved in E-NPCE process were optimized by single-factor experiments and then critical parameters were investigated by a 2 3 full factorial central composite design (CCD) to optimize extract conditions. Under optimal conditions, the yields of genistein and apigenin were 0.628 mg/g and 0.359 mg/g, which represented an increase of 44.70% and 53.05%, respectively, compared to standard NPCE. Furthermore, from DPPH scavenging activity test the extract of E-NPCE showed better antioxidant activity than t…
Adaptive backstepping based consensus tracking of uncertain nonlinear systems with event-triggered communication
Abstract This paper investigates the consensus tracking problem for a class of uncertain high-order nonlinear systems with parametric uncertainties and event-triggered communication. Under a directed communication condition, a totally distributed adaptive backstepping based control scheme is presented. Specifically, a decentralized triggering condition is adopted in this paper such that continuous monitoring of neighboring states, as required in some existing results, can be avoided. Besides, to handle the non-differentiability problem of virtual controllers, which arises from the utilization of neighboring states collected only at the triggering instants, the virtual controllers in each re…
Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study
Background Little information is available about the geo-economic variations in demographics, management, and outcomes of patients with acute respiratory distress syndrome (ARDS). We aimed to characterise the effect of these geo-economic variations in patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE). Methods LUNG SAFE was done during 4 consecutive weeks in winter, 2014, in a convenience sample of 459 intensive-care units in 50 countries across six continents. Inclusion criteria were admission to a participating intensive-care unit (including transfers) within the enrolment window and receipt of invasive or non…
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study (Intensive Care Medicine, (2021), 47, 2, (160-169), 10.1007/s00134-020-06234-9)
The original version of this article unfortunately contained a mistake. The members of the ESICM Trials Group Collaborators were not shown in the article but only in the ESM. The full list of collaborators is shown below. The original article has been corrected.
Electron and photon performance measurements with the ATLAS detector using the 2015-2017 LHC proton-proton collision data
This paper describes the reconstruction of electrons and photons with the ATLAS detector, employed for measurements and searches exploiting the complete LHC Run 2 dataset. An improved energy clustering algorithm is introduced, and its implications for the measurement and identification of prompt electrons and photons are discussed in detail. Corrections and calibrations that affect performance, including energy calibration, identification and isolation efficiencies, and the measurement of the charge of reconstructed electron candidates are determined using up to 81 fb−1 of proton-proton collision data collected at √s=13 TeV between 2015 and 2017.
Search for resonances in the mass distribution of jet pairs with one or two jets identified as b-jets in proton–proton collisions at s=13 TeV with the ATLAS detector
Searches for high-mass resonances in the dijet invariant mass spectrum with one or two jets identified as $b$-jets are performed using an integrated luminosity of $3.2$ fb$^{-1}$ of proton--proton collisions with a centre-of-mass energy of $\sqrt{s}=13$ TeV recorded by the ATLAS detector at the Large Hadron Collider. No evidence of anomalous phenomena is observed in the data, which are used to exclude, at 95% credibility level, excited $b^{*}$ quarks with masses from 1.1 TeV to 2.1 TeV and leptophobic $Z'$ bosons with masses from 1.1 TeV to 1.5 TeV. Contributions of a Gaussian signal shape with effective cross sections ranging from approximately 0.4 to 0.001 pb are also excluded in the mass…
Search for heavy resonances decaying to a photon and a hadronically decaying Z/W/H boson in pp collisions at s=13 TeV with the ATLAS detector
This Letter presents a search for the production of new heavy resonances decaying into a Higgs boson and a photon using proton-proton collision data at √ s = 13 TeV collected by the ATLAS detector at the LHC. The data correspond to an integrated luminosity of 139 fb − 1 . The analysis is performed by reconstructing hadronically decaying Higgs boson ( H → b ¯ b ) candidates as single large-radius jets. A novel algorithm using information about the jet constituents in the center-of-mass frame of the jet is implemented to identify the two b quarks in the single jet. No significant excess of events is observed above the expected background. Upper limits are set on the production cross-s…
Search for Higgs bosons produced via vector-boson fusion and decaying into bottom quark pairs in s=13 TeV pp collisions with the ATLAS detector
A search for the b (b) over bar decay of the Standard Model Higgs boson produced through vector-boson fusion is presented. Three mutually exclusive channels are considered: two all-hadronic channel ...
Distributed adaptive leader–follower and leaderless consensus control of a class of strict-feedback nonlinear systems : a unified approach
In this paper, distributed adaptive consensus for a class of strict-feedback nonlinear systems under directed topology condition is investigated. Both leader–follower and leaderless cases are considered in a unified framework. To design distributed controller for each subsystem, a local compensatory variable is generated based on the signals collected from its neighbors. Such a technique enables us to solve the leader–follower consensus and leaderless consensus problems in a unified framework. And it further allows us to treat the leaderless consensus as a special case of the leader–follower consensus. For leader–follower consensus, the assumption that the leader trajectory is linearly para…
Contribution to the flora of Asian and European countries: new national and regional vascular plant records, 8
The paper presents new records of 24 vascular plant species from 11 Eurasian countries. One taxon (Orobanche laxissima) is reported from Armenia ; one (Epipactis condensata) from Azerbaijan ; two (Phragmites americanus, Polygala multicaulis) from Belarus ; one (Stipa caucasica) from Egypt ; one (Puccinellia hauptiana) from Kyrgyzstan ; three (Aquilegia xinjiangensis, Geranium saxatile, Ranunculus songaricus) from Mongolia ; one (Stipa roborowskyi) from Pakistan ; three (Echinochloa muricata, Erigeron acris subsp. podolicus, Hypericum majus) from Poland ; six from Russia, whereof one (Zanthoxylum armatum) from the European part of Russia and five (Chaerophyllum aureum, Elsholtzia densa, Poa …
Search for new phenomena in dijet events using 37 fb−1 of pp collision data collected at s=13 TeV with the ATLAS detector
Dijet events are studied in the proton-proton collision dataset recorded at root s = 13 TeV with the ATLAS detector at the Large Hadron Collider in 2015 and 2016, corresponding to integrated lumino ...
Measurement of the suppression and azimuthal anisotropy of muons from heavy-flavor decays in Pb+Pb collisions at sNN=2.76 TeV with the ATLAS detector
ATLAS measurements of the production of muons from heavy-flavor decays in root s(NN) = 2.76 TeV Pb+Pb collisions and root s = 2.76 TeV pp collisions at the LHC are presented. Integrated luminositie ...
An effective negative pressure cavitation-microwave assisted extraction for determination of phenolic compounds in P. calliantha H. Andr.
A novel negative pressure and microwave assisted extraction technique (NMAE) was first proposed and applied for extraction of phenolic compounds from pyrola. [C₄MIM]BF₄ aqueous solution was selected as extraction solvent. Optimal extraction conditions were microwave power 700 W, negative pressure -0.07 MPa, temperature 40 °C, liquid-solid ratio 20 : 1, ionic liquid (IL) concentration 0.5 M, extraction time 15 min. The predominance of NMAE was investigated by comparing with microwave-assisted extraction (MAE) and negative pressure cavitation extraction (NPCE) using a first-order kinetics equation. The C∞ values of the target compounds by NMAE were from 0.406 to 5.977 mg g⁻¹ higher than these…
The Design and Sensitivity of JUNO's scintillator radiopurity pre-detector OSIRIS
The European physical journal / C 81(11), 973 (2021). doi:10.1140/epjc/s10052-021-09544-4
Study of BESIII trigger efficiencies with the 2018 J/psi data
Using a dedicated data sample taken in 2018 on the $J/\psi$ peak, we perform a detailed study of the trigger efficiencies of the BESIII detector. The efficiencies are determined from three representative physics processes, namely Bhabha-scattering, dimuon production and generic hadronic events with charged particles. The combined efficiency of all active triggers approaches $100\%$ in most cases with uncertainties small enough as not to affect most physics analyses.
Search for direct stau production in events with two hadronic τ -leptons in s=13 TeV pp collisions with the ATLAS detector
A search for the direct production of the supersymmetric partners of τ -leptons (staus) in final states with two hadronically decaying τ -leptons is presented. The analysis uses a dataset of p p collisions corresponding to an integrated luminosity of 139 fb − 1 , recorded with the ATLAS detector at the Large Hadron Collider at a center-of-mass energy of 13 TeV. No significant deviation from the expected Standard Model background is observed. Limits are derived in scenarios of direct production of stau pairs with each stau decaying into the stable lightest neutralino and one τ -lepton in simplified models where the two stau mass eigenstates are degenerate. Stau masses from 120 GeV to 390…
Adaptive Backstepping Control of Nonlinear Uncertain Systems With Quantized States
This paper investigates the stabilization problem for uncertain nonlinear systems with quantized states. All states in the system are quantized by a static bounded quantizer, including uniform quantizer, hysteresis-uniform quantizer, and logarithmic-uniform quantizer as examples. An adaptive backstepping-based control algorithm, which can handle discontinuity, resulted from the state quantization and a new approach to stability analysis are developed by constructing a new compensation scheme for the effects of the state quantization. Besides showing the global ultimate boundedness of the system, the stabilization error performance is also established and can be improved by appropriately adj…
Combination of the Searches for Pair-Produced Vectorlike Partners of the Third-Generation Quarks at s=13 TeV with the ATLAS Detector
A combination of the searches for pair-produced vectorlike partners of the top and bottom quarks in various decay channels (T -> Zt/Wb/Ht, B -> Zb/Wt/Hb) is performed using 36.1 fb(-1) of pp ...
Efficient extraction and preparative separation of four main isoflavonoids from Dalbergia odorifera T. Chen leaves by deep eutectic solvents-based negative pressure cavitation extraction followed by macroporous resin column chromatography
In this study, green and efficient deep eutectic solvent-based negative pressure cavitation-assisted extraction (DES-NPCE) followed by macroporous resin column chromatography was developed to extract and separate four main isoflavonoids, i.e. prunetin, tectorigenin, genistein and biochanin A from Dalbergia odorifera T. Chen leaves. The extraction procedure was optimized systematically by single-factor experiments and a Box-Behnken experimental design combined with response surface methodology. The maximum extraction yields of prunetin, tectorigenin, genistein and biochanin A reached 1.204, 1.057, 0.911 and 2.448mg/g dry weight, respectively. Moreover, the direct enrichment and separation of…
Search for squarks and gluinos in final states with hadronically decaying τ -leptons, jets, and missing transverse momentum using pp collisions at s=13 TeV with the ATLAS detector
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying τ-lepton is presented. Two exclusive final states with either exactly one or at least two τ-leptons are considered. The analysis is based on proton-proton collisions at s=13 TeV corresponding to an integrated luminosity of 36.1 fb-1 delivered by the Large Hadron Collider and recorded by the ATLAS detector in 2015 and 2016. No significant excess is observed over the Standard Model expectation. At 95% confidence level, model-independent upper limits on the cross section are set and exclusion limits are provided for two signal scenarios: a simplified model of gluino pair pr…
Adaptive Control Design for Underactuated Cranes With Guaranteed Transient Performance: Theoretical Design and Experimental Verification
For antiswing control of underactuated cranes, how to guarantee the converging speed of cranes through control design is essential but still remains unsolved. In this paper, the adaptive antiswing control for underactuated gantry cranes with guaranteed transient performance under unmodeled dynamics and external disturbances is investigated. To sovle this problem, a set of filters are proposed to make the backstepping technique applicable for the control of crane systems. Then through variable transformation the position error and swing angel could be guaranteed converging to the origin with a given exponential speed. Hardware experiments are conducted to show that the proposed scheme achiev…
Radioactivity control strategy for the JUNO detector
JUNO is a massive liquid scintillator detector with a primary scientific goal of determining the neutrino mass ordering by studying the oscillated anti-neutrino flux coming from two nuclear power plants at 53 km distance. The expected signal anti-neutrino interaction rate is only 60 counts per day, therefore a careful control of the background sources due to radioactivity is critical. In particular, natural radioactivity present in all materials and in the environment represents a serious issue that could impair the sensitivity of the experiment if appropriate countermeasures were not foreseen. In this paper we discuss the background reduction strategies undertaken by the JUNO collaboration…
Search for a right-handed gauge boson decaying into a high-momentum heavy neutrino and a charged lepton in pp collisions with the ATLAS detector at s=13 TeV
A search for a right-handed gauge boson WR, decaying into a boosted right-handed heavy neutrino NR, in the framework of Left-Right Symmetric Models is presented. It is based on data from proton–proton collisions with a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider during the years 2015, 2016 and 2017, corresponding to an integrated luminosity of 80 fb$^{−1}$. The search is performed separately for electrons and muons in the final state. A distinguishing feature of the search is the use of large-radius jets containing electrons. Selections based on the signal topology result in smaller background compared to the expected signal. No significant d…
Longitudinal Flow Decorrelations in Xe+Xe Collisions at sNN=5.44 TeV with the ATLAS Detector
The first measurement of longitudinal decorrelations of harmonic flow amplitudes v_{n} for n=2-4 in Xe+Xe collisions at sqrt[s_{NN}]=5.44 TeV is obtained using 3 μb^{-1} of data with the ATLAS detector at the LHC. The decorrelation signal for v_{3} and v_{4} is found to be nearly independent of collision centrality and transverse momentum (p_{T}) requirements on final-state particles, but for v_{2} a strong centrality and p_{T} dependence is seen. When compared with the results from Pb+Pb collisions at sqrt[s_{NN}]=5.02 TeV, the longitudinal decorrelation signal in midcentral Xe+Xe collisions is found to be larger for v_{2}, but smaller for v_{3}. Current hydrodynamic models reproduce th…
H<inf>&#x221E;</inf> control for stochastic switched delay systems with missing measurements: An average dwell time approach
In this paper, the problem of non-fragile observer-based H ∞ control for discrete-time switched delay systems is investigated. Both data missing and time delays are taken into account in the links from sensors to observers and from controllers to actuators. Such problem is transformed into an H ∞ control problem for stochastic switched delay systems. Average dwell time (ADT) approach is used to obtain sufficient conditions on the solvability of such problems. An example is provided to show the effectiveness of the proposed method.
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Abstract Incubation pretreatment with the function of endogenous enzyme combined with negative-pressure cavitation extraction (IP-NPCE) was established to extract calycosin and formononetin from Radix Astragali. Significant factors involved in the process were selected using Plackett–Burman factorial design (PBD) and then were optimized by central composite design (CCD). The optimum experimental conditions were incubation at 35 °C, 60 min, pH 4.0 and extraction at negative pressure − 0.080 MPa, ethanol concentration 60%, 60 mesh, 30 min, solid-to-liquid ratio 1:25 and two cycles. Under the optimal conditions, the extraction yields of calycosin and formononetin were 0.650 ± 0.015 and 0.307 ±…
Search for supersymmetry in events with four or more leptons in s=13 TeV pp collisions with ATLAS
Results from a search for supersymmetry in events with four or more charged leptons (electrons, muons and taus) are presented. The analysis uses a data sample corresponding to 36.1 fb-1 of proton-proton collisions delivered by the Large Hadron Collider at s=13 TeV and recorded by the ATLAS detector. Four-lepton signal regions with up to two hadronically decaying taus are designed to target a range of supersymmetric scenarios that can be either enriched in or depleted of events involving the production and decay of a Z boson. Data yields are consistent with Standard Model expectations and results are used to set upper limits on the event yields from processes beyond the Standard Model. Exclu…
Observation of Centrality-Dependent Acoplanarity for Muon Pairs Produced via Two-Photon Scattering in Pb+Pb Collisions at sNN=5.02 TeV with the ATLAS Detector
This Letter presents a measurement of γγ→μ^{+}μ^{-} production in Pb+Pb collisions recorded by the ATLAS detector at the Large Hadron Collider at sqrt[s_{NN}]=5.02 TeV with an integrated luminosity of 0.49 nb^{-1}. The azimuthal angle and transverse momentum correlations between the muons are measured as a function of collision centrality. The muon pairs are produced from γγ through the interaction of the large electromagnetic fields of the nuclei. The contribution from background sources of muon pairs is removed using a template fit method. In peripheral collisions, the muons exhibit a strong back-to-back correlation consistent with previous measurements of muon pair production in ultrap…
Cholesterol Dependence of Collagen and Echovirus 1 Trafficking along the Novel α2β1 Integrin Internalization Pathway
We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes. Here we show that cholesterol plays a major role not only in the uptake of α2β1 integrin and its ligands but also in the formation of α2 integrin-specific multivesicular bodies (α2-MVBs) and virus infection. EV1 infection and α2β1 integrin internalization were totally halted by low amounts of the cholesterol-aggregating drugs filipin or nystatin. Inhibition of cholesterol synthesis and accumulation of lanosterol after ketoconazole treatment inhibited uptake of collagen, virus and clustered integrin, an…
UV-Induced Changes of Active Components and Antioxidant Activity in Postharvest Pigeon Pea [Cajanus cajan (L.) Millsp.] Leaves
In this study, the effect of UV irradiation (UV-A, UV-B, and UV-C) on phytochemicals, total phenolics, and antioxidant activity of postharvest pigeon pea leaves was evaluated. The response of pigeon pea leaves to UV irradiation was phytochemical specific. UV-B and UV-C induced higher levels of phytochemicals, total phenolics, and antioxidant activity in pigeon pea leaves compared with UV-A. Furthermore, UV-B irradiation proved to possess a long-lasting effect on the levels of phenolics and antioxidant activity. After adapting for 48 h at 4 °C following 4 h UV-B irradiation, total phenolics and antioxidant activity were approximately 1.5-fold and 2.2-fold increased from 39.4 mg GAE/g DM and …
Search for photonic signatures of gauge-mediated supersymmetry in 8TeV pp collisions with the ATLAS detector
A search is presented for photonic signatures motivated by generalized models of gauge-mediated supersymmetry breaking. This search makes use of 20.3 fb[superscript −1] of proton-proton collision data at √s = 8 TeV recorded by the ATLAS detector at the LHC, and explores models dominated by both strong and electroweak production of supersymmetric partner states. Four experimental signatures incorporating an isolated photon and significant missing transverse momentum are explored. These signatures include events with an additional photon, lepton, b-quark jet, or jet activity not associated with any specific underlying quark flavor. No significant excess of events is observed above the Stand…
Adaptive control of a drilling system with unknown time-delay and disturbance
In this paper, we address adaptive predictor feedback design for a simplified drilling system in the presence of disturbance and time-delay. The main objective is to stabilize the bottomhole pressure at a critical depth at a desired set-point directly. The stabilization of the dynamic system and the asymptotic tracking are demonstrated by the proposed adaptive control, where the adaptation employs Lyapunov update law design with normalization. The proposed method is evaluated using a high fidelity drilling simulator and cases from a North Sea drilling operation are simulated. The results show that the proposed predictor controller is effective to stabilize the bottom hole pressure within th…
CP Properties of Higgs Boson Interactions with Top Quarks in the tt¯H and tH Processes Using H→γγ with the ATLAS Detector
A study of the charge conjugation and parity (CP) properties of the interaction between the Higgs boson and top quarks is presented. Higgs bosons are identified via the diphoton decay channel (H→γγ), and their production in association with a top quark pair (tt[over ¯]H) or single top quark (tH) is studied. The analysis uses 139 fb^{-1} of proton-proton collision data recorded at a center-of-mass energy of sqrt[s]=13 TeV with the ATLAS detector at the Large Hadron Collider. Assuming a CP-even coupling, the tt[over ¯]H process is observed with a significance of 5.2 standard deviations. The measured cross section times H→γγ branching ratio is 1.64_{-0.36}^{+0.38}(stat)_{-0.14}^{+0.17}(sys) …
Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
International audience; Gain-of-function mutations in some genes underlie neurodegenerative conditions, whereas loss-of-function mutations in the same genes have distinct phenotypes. This appears to be the case with the protein ataxin 1 (ATXN1), which forms a transcriptional repressor complex with capicua (CIC). Gain of function of the complex leads to neurodegeneration, but ATXN1-CIC is also essential for survival. We set out to understand the functions of the ATXN1-CIC complex in the developing forebrain and found that losing this complex results in hyperactivity, impaired learning and memory, and abnormal maturation and maintenance of upper-layer cortical neurons. We also found that CIC …
Antioxidant properties, superoxide dismutase and glutathione reductase activities in HepG2 cells with a fungal endophyte producing apigenin from pigeon pea [Cajanus cajan (L.) Millsp.]
Abstract A fungal endophyte MD89 with obvious antioxidant activities was isolated from pigeon pea and identified as Chaetomium globosum by ITS sequence. Different fractions from MD89 culture were compared and evaluated by total phenol (TP) content, total flavonoid (TFL) content, DPPH radical scavenging, reducing power and lipid peroxidation assays, respectively. Results showed that EtOAc extracts had high content of TP and TFL, and strong antioxidant activities (IC 50 value was 6.87, 15.19, 16.78 μg/mL, respectively). Furthermore, the EtOAc extracts were analyzed by LC–MS/MS and a good antioxidant compound, apigenin, was found. The activities of superoxide dismutase (SOD) and glutathione re…
Measurement of Azimuthal Anisotropy of Muons from Charm and Bottom Hadrons in pp Collisions at s=13 TeV with the ATLAS Detector
The elliptic flow of muons from the decay of charm and bottom hadrons is measured in pp collisions at sqrt[s]=13 TeV using a data sample with an integrated luminosity of 150 pb^{-1} recorded by the ATLAS detector at the LHC. The muons from heavy-flavor decay are separated from light-hadron decay muons using momentum imbalance between the tracking and muon spectrometers. The heavy-flavor decay muons are further separated into those from charm decay and those from bottom decay using the distance-of-closest-approach to the collision vertex. The measurement is performed for muons in the transverse momentum range 4-7 GeV and pseudorapidity range |η|<2.4. A significant nonzero elliptic anisotro…
Adaptive backstepping control of uncertain systems in the presence of unmodeled dynamics and time-varying delays
In this paper, the problem of adaptive backstepping control for uncertain systems in the presence of unmodeled dynamics and input time-varying delays is studied. Under some mild assumptions, a robust adaptive controller is designed such that the system is globally stabilized by using adaptive backstepping technique. Meanwhile, the transient system performance in L2 and norms of system output can be adjusted by choosing the design parameters. Finally, a simulation example is given to show the effectiveness of the results.
Properties and distribution of paired candidate stony meteorites at Meridiani Planum, Mars
[1] The Mars Exploration Rover Opportunity investigated four rocks, informally dubbed Barberton, Santa Catarina, Santorini, and Kasos, that are possible stony meteorites. Their chemical and mineralogical composition is similar to the howardite, eucrite, and diogenite group but with additional metal, similar to mesosiderite silicate clasts. Because of their virtually identical composition and because they appear to represent a relatively rare group of meteorites, they are probably paired. The four rocks were investigated serendipitously several kilometers apart, suggesting that Opportunity is driving across a larger population of similar rock fragments, maybe a meteorite strewn field. Small …
2′-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo
2'-O-galloylhyperin, a major compound of Pyrola incarnata Fisch., possesses a variety of biological and pharmacological activities, including anti-oxidative and anti-inflammatory activities. Nevertheless, the underlying molecular mechanisms of 2'-O-GH in microbial infection and sepsis are not clear. In this study, we investigated the anti-inflammatory effects of 2'-O-GH. We found that 2'-O-GH significantly reduced the production of TNF-α, IL-6, and nitric oxide (NO), suppressed the expression levels of iNOS, blocked the translocation of NF-κB from the cytosol to nucleus, and decreased the MAPK activation in LPS-activated RAW 264.7 cells. 2'-O-GH also enhanced the nuclear translocation of Nr…
Negative-pressure cavitation coupled with aqueous two-phase extraction and enrichment of flavonoids and stilbenes from the pigeon pea leaves and the evaluation of antioxidant activities
Abstract An efficient extraction method, negative-pressure cavitation coupled with aqueous two-phase extraction (NPC-ATPE), was developed to simultaneously extract and enrich flavonoids and stilbenes from pigeon pea leaves. The main bioactive compounds, cajaninstilbene acid (CSA), longistyline C (LLC), pinostrobin (PI) and pinostrobin chalcone (PIC) were chosen as target compounds. The extraction conditions were optimized using central composite design combined with response surface methodology. The optimized conditions were: concentration of (NH 4 ) 2 SO 4 21% (w/w), concentration of ethanol 23% (w/w) and temperature 30 °C, negative pressure −0.06 MPa, extraction time 30 min and the liquid…
Observation of the doubly radiative decay η′→γγπ0
Based on a sample of 1.31 billion J/psi events collected with the BESIII detector, we report the study of the doubly radiative decay eta' -> gamma gamma pi(0) for the first time, where the eta' meson is produced via the J/psi -> gamma eta' decay. The branching fraction of eta' -> gamma gamma pi(0) inclusive decay is measured to be B(eta' -> gamma gamma pi(0))(Incl) = (3.20 +/- 0.07(stat) +/- 0.23(sys)) x 10(-3), while the branching fractions of the dominant process eta' -> gamma omega and the non-resonant component are determined to be B(eta' -> gamma omega) x B(omega -> gamma pi(0)) = (23.7 +/- 1.4(stat) +/- 1.8(sys)) x 10(-4) and B(eta' -> gamma gamma pi(0))(NR) = (6.16 +/- 0.64(stat) +/-…
Medium-Induced Modification of Z -Tagged Charged Particle Yields in Pb+Pb Collisions at 5.02 TeV with the ATLAS Detector
The yield of charged particles opposite to a Z boson with large transverse momentum (p_{T}) is measured in 260 pb^{-1} of pp and 1.7 nb^{-1} of Pb+Pb collision data at 5.02 TeV per nucleon pair recorded with the ATLAS detector at the Large Hadron Collider. The Z boson tag is used to select hard-scattered partons with specific kinematics, and to observe how their showers are modified as they propagate through the quark-gluon plasma created in Pb+Pb collisions. Compared with pp collisions, charged-particle yields in Pb+Pb collisions show significant modifications as a function of charged-particle p_{T} in a way that depends on event centrality and Z boson p_{T}. The data are compared with a…
Search for bottom-squark pair production in pp collision events at s=13 TeV with hadronically decaying τ -leptons, b -jets, and missing transverse momentum using the ATLAS detector
A search for pair production of bottom squarks in events with hadronically decaying τ-leptons, b-tagged jets, and large missing transverse momentum is presented. The analyzed dataset is based on proton-proton collisions at s=13 TeV delivered by the Large Hadron Collider and recorded by the ATLAS detector from 2015 to 2018, and corresponds to an integrated luminosity of 139 fb-1. The observed data are compatible with the expected Standard Model background. Results are interpreted in a simplified model where each bottom squark is assumed to decay into the second-lightest neutralino χ 20 and a bottom quark, with χ 20 decaying into a Higgs boson and the lightest neutralino χ 10. The search focu…
Adaptive Control of Quantized Uncertain Nonlinear Systems
Abstract This paper proposes a new adaptive controller for uncertain nonlinear systems in presence of quantized input signal and unknown external disturbance. A hysteresis quantizer is incorporated to reduce chattering phenomenon. By proposing a new transformation of the final control signal, using the sector-bound property of the quantizer and introducing a hyperbolic tangent function, the effects from input quantization and external disturbance are effectively compensated and the Lipschitz condition required for the nonlinear functions in the systems is removed. Besides showing global stability, tracking error performance is also established and can be adjusted by tuning certain design pa…
Non-fragile H ∞ control for switched stochastic delay systems with application to water quality process
SUMMARY In this paper, the problem of non-fragile observer-based H ∞ control for discrete-time switched delay systems is investigated. Both data missing and time delays are taken into account in the links from sensors to observers and from controllers to actuators. Because data missing satisfies the Bernoulli distribution, such problem is transformed into an H ∞ control problem for stochastic switched delay systems. Average dwell time approach is used to obtain sufficient conditions on the solvability of such problems. A numerical example and a real example for water quality control are provided to illustrate the effectiveness and potential applications of the proposed techniques. Copyrig…
Search for the Higgs boson decays H → ee and H → eμ in pp collisions at s=13TeV with the ATLAS detector
Searches for the Higgs boson decays H -> ee and H -> e mu are performed using data corresponding to an integrated luminosity of 139 fb(-1) collected with the ATLAS detector in pp collisions a ...
Combination of Searches for Invisible Higgs Boson Decays with the ATLAS Experiment
Dark matter particles, if sufficiently light, may be produced in decays of the Higgs boson. This Letter presents a statistical combination of searches for H → invisible decays where H is produced according to the standard model via vector boson fusion, Z(ℓℓ)H, and W/Z(had)H, all performed with the ATLAS detector using 36.1 fb⁻¹ of pp collisions at a center-of-mass energy of √s = 13 TeV at the LHC. In combination with the results at √s = 7 and 8 TeV, an exclusion limit on the H → invisible branching ratio of 0.26(0.17-0.05+0.07) at 95% confidence level is observed (expected).
Search for invisible Higgs boson decays in vector boson fusion at s=13TeV with the ATLAS detector
We report a search for Higgs bosons that are produced via vector boson fusion and subsequently decay into invisible particles. The experimental signature is an energetic jet pair with invariant mass of O(1)TeV and O(100)GeV missing transverse momentum. The analysis uses 36.1 fb −1 of pp collision data at s=13TeV recorded by the ATLAS detector at the LHC. In the signal region the 2252 observed events are consistent with the background estimation. Assuming a 125GeV scalar particle with Standard Model cross sections, the upper limit on the branching fraction of the Higgs boson decay into invisible particles is 0.37 at 95% confidence level where 0.28 was expected. This limit is interpreted in H…
Search for resonant WZ production in the fully leptonic final state in proton–proton collisions at s=13TeV with the ATLAS detector
A search for a heavy resonance decaying into WZ in the fully leptonic channel (electrons and muons) is performed. It is based on proton–proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 36.1 fb −1 . No significant excess is observed over the Standard Model predictions and limits are set on the production cross section times branching ratio of a heavy vector particle produced either in quark–antiquark fusion or through vector-boson fusion. Constraints are also obtained on the mass and couplings of a singly charged Higgs boson, in the Georgi–Machacek model, produced through ve…
Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database
Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiog…
Evidence for the production of three massive vector bosons with the ATLAS detector
A search for the production of three massive vector bosons in proton–proton collisions is performed using data at TeV recorded with the ATLAS detector at the Large Hadron Collider in the years 2015–2017, corresponding to an integrated luminosity of 79.8 fb−1. Events with two same-sign leptons ℓ (electrons or muons) and at least two reconstructed jets are selected to search for . Events with three leptons without any same-flavour opposite-sign lepton pairs are used to search for , while events with three leptons and at least one same-flavour opposite-sign lepton pair and one or more reconstructed jets are used to search for . Finally, events with four leptons are analysed to search for and .…
Distributed Adaptive Consensus Tracking Control of Uncertain High-order Nonlinear Systems under Directed Graph Condition
In this paper, we investigate the output consensus tracking problem for a class of high-order nonlinear systems subjected to unknown parameters and uncertain external disturbances. A novel backstepping based distributed adaptive control scheme is presented under the directed communication status. For the subsystems without direct access to time-varying desired trajectory, local estimators are introduced and the corresponding adaptive laws are designed in a totally distributed fashion. With the presented scheme, the assumption on linearly parameterized reference signal and the information exchange operation of subsystem inputs in the existing results are no longer needed. It is shown that al…
Observation of e + e − → ηψ(2S) at center-of-mass energies from 4.236 to 4.600 GeV
Journal of high energy physics 2021(10), 177 (2021). doi:10.1007/JHEP10(2021)177
Search for a heavy charged boson in events with a charged lepton and missing transverse momentum from pp collisions at s=13 TeV with the ATLAS detector
A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb−1 of proton-proton collisions at √s=13 TeV collected with the ATLAS detector at the LHC during 2015–2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distribution expected from the Standard Model, and upper limits on the cross section for pp→W′→lν are extracted (l=e or μ). These vary between 1.3 pb and 0.05 fb depending on the resonance mass in the range between 0.15 and 7.0 TeV at 95% confidence level for the electron and muon channels combined. …
Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13TeV with the ATLAS detector
A test of CP invariance in Higgs boson production via vector-boson fusion is performed in the H → ττ decay channel. This test uses the Optimal Observable method and is carried out using 36.1 fb−1 of √s = 13 TeV proton–proton collision data collected by the ATLAS experiment at the LHC. Contributions from CP-violating interactions between the Higgs boson and electroweak gauge bosons are described by an effective field theory, in which the parameter ˜ d governs the strength of CP violation. No sign of CP violation is observed in the distributions of the Optimal Observable, and ˜ d is constrained to the interval [−0.090, 0.035] at the 68% confidence level (CL), compared to an expected interval …
Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis
Item does not contain fulltext BACKGROUND: Two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory and hypoinflammatory) with distinct clinical and biological features and differential treatment responses have been identified using latent class analysis (LCA) in seven individual cohorts. To facilitate bedside identification of subphenotypes, clinical classifier models using readily available clinical variables have been described in four randomised controlled trials. We aimed to assess the performance of these models in observational cohorts of ARDS. METHODS: In this observational, multicohort, retrospective study, we validated two machine-learning clinical classifie…
Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin
Abstract Radix Astragali is considered an excellent source of Traditional Chinese Medicine and a kind of famous restorative food. To make full usage of Radix Astragali, calycosin and formononetin were enriched through various macroporous resins from its residues, HPD500 resin, compared with other resins, offered the best effectiveness for the enrichment and separation of compounds. 35 °C was selected for its highest adoption capacity during static adsorption process, which can be obtained from adsorption isotherms. And then dynamic adsorption and desorption tests were carried out to optimize the operating parameters. After one run treatment with HPD500 resin, the contents of calycosin and f…
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study
Supported by Centro de Investigación Biomédica en Red (CIBER)‑Enfermedades respiratorias, Madrid, Spain (CB17/06/00021) and Fundación para el Fomento en Asturias de la Investigación Científica aplicada y la tecnología (FICYT, AYUD2021/52014). RRG is the recipient of a grant from Instituto de Salud Carlos III, Madrid, Spain (CM20/00083).
Search for Heavy Higgs Bosons Decaying into Two Tau Leptons with the ATLAS Detector Using pp Collisions at s=13 TeV
A search for heavy neutral Higgs bosons is performed using the LHC Run 2 data, corresponding to an integrated luminosity of 139 fb^{-1} of proton-proton collisions at sqrt[s]=13 TeV recorded with the ATLAS detector. The search for heavy resonances is performed over the mass range 0.2-2.5 TeV for the τ^{+}τ^{-} decay with at least one τ-lepton decaying into final states with hadrons. The data are in good agreement with the background prediction of the standard model. In the M_{h}^{125} scenario of the minimal supersymmetric standard model, values of tanβ>8 and tanβ>21 are excluded at the 95% confidence level for neutral Higgs boson masses of 1.0 and 1.5 TeV, respectively, where tanβ is the…
Search for heavy particles decaying into a top-quark pair in the fully hadronic final state in pp collisions at s=13 TeV with the ATLAS detector
A search for new particles decaying into a pair of top quarks is performed using proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider at a center-of-mass energ ...
Valence change ReRAMs (VCM) - Experiments and modelling: General discussion
Valence change ReRAMs (VCM) - Experiments and modelling: General discussion
Search for heavy charged long-lived particles in proton–proton collisions at s=13TeV using an ionisation measurement with the ATLAS detector
This Letter presents a search for heavy charged long-lived particles produced in proton-proton collisions at root s= 13 TeV at the LHC using a data sample corresponding to an integrated luminosity ...
Observation of Electroweak Production of a Same-Sign W Boson Pair in Association with Two Jets in pp Collisions at s=13 TeV with the ATLAS Detector
This Letter presents the observation and measurement of electroweak production of a same-sign W boson pair in association with two jets using 36.1 fb^{-1} of proton-proton collision data recorded at a center-of-mass energy of sqrt[s]=13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed in the detector fiducial phase-space region, defined by the presence of two same-sign leptons, electron or muon, and at least two jets with a large invariant mass and rapidity difference. A total of 122 candidate events are observed for a background expectation of 69±7 events, corresponding to an observed signal significance of 6.5 standard deviations. The measured fiducial s…
Contribution to the flora of Asian and European countries: new national and regional vascular plant records, 7
The paper presents new records for 29 vascular plant species from 12 Eurasian countries. Seven taxa (Agave sisalana, Austrocylindropuntia subulata, Lagurus ovatus subsp. nanus, Opuntia stricta, Orobanche serbica, Oxalis articulata, Vitis Ã instabilis) are reported from Albania, one (Allium carinatum) from the Europaean part of Russia, six (Dipsacus fullonum, Gagea shmakoviana, Mentha Ã dalmatica, Thymus indigirkensis, Thymus sergievskajae, Viola Ã sukaczewii) from the Asian part of Russia, two (Agrostis sozanensis, Poa mustangensis) from China, two (Carex muskingumensis, Sedum rubens) from Poland, two (Crataegus macrocarpa, Dactylorhiza lapponica) from Romania, two (Oxygraphis dela…
JUNO sensitivity to low energy atmospheric neutrino spectra
Atmospheric neutrinos are one of the most relevant natural neutrino sources that can be exploited to infer properties about cosmic rays and neutrino oscillations. The Jiangmen Underground Neutrino Observatory (JUNO) experiment, a 20 kton liquid scintillator detector with excellent energy resolution is currently under construction in China. JUNO will be able to detect several atmospheric neutrinos per day given the large volume. A study on the JUNO detection and reconstruction capabilities of atmospheric $\nu_e$ and $\nu_\mu$ fluxes is presented in this paper. In this study, a sample of atmospheric neutrino Monte Carlo events has been generated, starting from theoretical models, and then pro…
Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study
BackgroundCurrent incidence and outcome of patients with acute hypoxaemic respiratory failure requiring mechanical ventilation in the intensive care unit (ICU) are unknown, especially for patients not meeting criteria for acute respiratory distress syndrome (ARDS).MethodsAn international, multicentre, prospective cohort study of patients presenting with hypoxaemia early in the course of mechanical ventilation, conducted during four consecutive weeks in the winter of 2014 in 459 ICUs from 50 countries (LUNG SAFE). Patients were enrolled with arterial oxygen tension/inspiratory oxygen fraction ratio ≤300 mmHg, new pulmonary infiltrates and need for mechanical ventilation with a positive end-e…
Measurement of the tt¯Z and tt¯W cross sections in proton-proton collisions at s=13 TeV with the ATLAS detector
A measurement of the associated production of a top-quark pair (tt) with a vector boson (W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV is presented, using 36.1 fb-1 of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. Events are selected in channels with two same- or opposite-sign leptons (electrons or muons), three leptons or four leptons, and each channel is further divided into multiple regions to maximize the sensitivity of the measurement. The ttZ and ttW production cross sections are simultaneously measured using a combined fit to all regions. The best-fit values of the production cross sections are σttZ=0.95±0.08stat±0.10syst…
ATLAS data quality operations and performance for 2015-2018 data-taking
The ATLAS detector at the Large Hadron Collider reads out particle collision data from over 100 million electronic channels at a rate of approximately 100 kHz, with a recording rate for physics events of approximately 1 kHz. Before being certified for physics analysis at computer centres worldwide, the data must be scrutinised to ensure they are clean from any hardware or software related issues that may compromise their integrity. Prompt identification of these issues permits fast action to investigate, correct and potentially prevent future such problems that could render the data unusable. This is achieved through the monitoring of detector-level quantities and reconstructed collision ev…
Search for lepton-flavor-violating decays of the Z boson into a τ lepton and a light lepton with the ATLAS detector
Direct searches for lepton flavor violation in decays of the Z boson with the ATLAS detector at the LHC are presented. Decays of the Z boson into an electron or muon and a hadronically decaying r l ...
Search for heavy long-lived multicharged particles in proton-proton collisions at s=13 TeV using the ATLAS detector
A search for heavy long-lived multicharged particles is performed using the ATLAS detector at the LHC. Data with an integrated luminosity of 36.1 fb(-1) collected in 2015 and 2016 from proton-proto ...
Observation of Higgs boson production in association with a top quark pair at the LHC with the ATLAS detector
Physics letters / B 784, 173 - 191 (2018). doi:10.1016/j.physletb.2018.07.035
Neutrino Physics with JUNO
The Jiangmen Underground Neutrino Observatory (JUNO), a 20 kton multi-purpose underground liquid scintillator detector, was proposed with the determination of the neutrino mass hierarchy as a primary physics goal. It is also capable of observing neutrinos from terrestrial and extra-terrestrial sources, including supernova burst neutrinos, diffuse supernova neutrino background, geoneutrinos, atmospheric neutrinos, solar neutrinos, as well as exotic searches such as nucleon decays, dark matter, sterile neutrinos, etc. We present the physics motivations and the anticipated performance of the JUNO detector for various proposed measurements. By detecting reactor antineutrinos from two power plan…
Adaptive Backstepping Control of Uncertain Nonlinear Systems With Input and State Quantization
Though it is common in network control systems that the sensor and control signals are transmitted via a common communication network, no result is available in investigating the stabilization problem for uncertain nonlinear systems with both input and state quantization. The issue is solved in this paper, by presenting an adaptive backstepping based control algorithm for the systems with sector bounded input and state quantizers. In addition to overcome the difficulty to proceed recursive design of virtual controls with quantized states, the relation between the input signal and error state need be well established to handle the effects due to quantization. It is shown that all closed-loop…
Combination of searches for heavy resonances decaying into bosonic and leptonic final states using 36 fb−1 of proton-proton collision data at s=13 TeV with the ATLAS detector
Searches for new heavy resonances decaying into different pairings of W, Z, or Higgs bosons, as well as dirffiffiffiectly into leptons, are presented using a data sample corresponding to 36.1 fb(-1 ...
Contribution to the flora of Asian and European countries: new national and regional vascular plant records, 6
The paper presents new records for 10 vascular plant species from three Asian and four European countries. Of this number, three species (Panicum capillare, Stipa macroglossa, Tribulus longipetalus) are reported from Tajikistan, two (Calamagrostis emodensis, Calamagrostis lahulensis) from Myanmar, two (Euphorbia taurinensis, Origanum vulgare var. megastachyum) from Poland, one (Sagina apetala) from Uzbekistan, one (Orobanche ritro) from Ukraine and Russia, and one (Leontodon saxatilis) from the Czech Republic. Eight of these taxa are new to the flora of different Asian and European countries; and two, very rare but recently spreading species, namely Leontodon saxatilis and Euphorbia taurine…
Optical Coherence Tomography Versus Intravascular Ultrasound to Evaluate Coronary Artery Disease and Percutaneous Coronary Intervention
ObjectivesWe compared intravascular ultrasound (IVUS) and 2 different generations of optical coherence tomography (OCT)—time-domain OCT (TD-OCT) and frequency-domain OCT (FD-OCT)—for the assessment of coronary disease and percutaneous coronary intervention (PCI) using stents.BackgroundOCT is a promising light-based intravascular imaging modality with higher resolution than IVUS. However, the paucity of data on OCT image quantification has limited its application in clinical practice.MethodsA total of 227 matched OCT and IVUS pull backs were studied. One hundred FD-OCT and IVUS pull backs in nonstented (n = 56) and stented (n = 44) vessels were compared. Additionally, 127 matched TD-OCT and …
Search for a heavy Higgs boson decaying into a Z boson and another heavy Higgs boson in the ℓℓbb final state in pp collisions at s=13 TeV with the ATLAS detector
A search for a heavy neutral Higgs boson, A, decaying into a Z boson and another heavy Higgs boson, H, is performed using a data sample corresponding to an integrated luminosity of 36.1 fb(-1) from ...
Search for heavy charged long-lived particles in the ATLAS detector in 36.1 fb−1 of proton-proton collision data at s=13 TeV
A search for heavy charged long-lived particles is performed using a data sample of 36.1 fb−1 of proton-proton collisions at s=13 TeV collected by the ATLAS experiment at the Large Hadron Collider. The search is based on observables related to ionization energy loss and time of flight, which are sensitive to the velocity of heavy charged particles traveling significantly slower than the speed of light. Multiple search strategies for a wide range of lifetimes, corresponding to path lengths of a few meters, are defined as model independently as possible, by referencing several representative physics cases that yield long-lived particles within supersymmetric models, such as gluinos/squarks …
Search for Higgs boson decays into pairs of light (pseudo)scalar particles in the γγjj final state in pp collisions at s=13TeV with the ATLAS detector
This Letter presents a search for exotic decays of the Higgs boson to a pair of new (pseudo)scalar particles, H→aa , where the a particle has a mass in the range 20–60 GeV, and where one of the a bosons decays into a pair of photons and the other to a pair of gluons. The search is performed in event samples enhanced in vector-boson fusion Higgs boson production by requiring two jets with large invariant mass in addition to the Higgs boson candidate decay products. The analysis is based on the full dataset of pp collisions at s=13TeV recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider, corresponding to an integrated luminosity of 36.7 fb −1 . The data are in a…
Adaptive control of uncertain nonlinear systems with quantized input signal
Abstract This paper proposes new adaptive controllers for uncertain nonlinear systems in the presence of input quantization. The control signal is quantized by a class of sector-bounded quantizers including the uniform quantizer, the logarithmic quantizer and the hysteresis quantizer. To clearly illustrate our approaches, we will start with a class of single-loop nonlinear systems and then extend the results to multi-loop interconnected nonlinear systems. By using backstepping technique, a new adaptive control algorithm is developed by constructing a new compensation method for the effects of the input quantization. A hyperbolic tangent function is introduced in the controller with a new tr…
Search for lepton-flavor violation in different-flavor, high-mass final states in pp collisions at s=13 TeV with the ATLAS detector
A search is performed for a heavy particle decaying into different-flavor, dilepton pairs (e mu, e tau or mu tau), using 36.1 fb(-1) of proton-proton collision data at root s = 13 TeV collected in ...
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: Insights from the LUNG SAFE study
Abstract Background Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence o…
Search for Dark Matter Produced in Association with a Dark Higgs Boson Decaying into W±W∓ or ZZ in Fully Hadronic Final States from s=13 TeV pp Collisions Recorded with the ATLAS Detector
Several extensions of the Standard Model predict the production of dark matter particles at the LHC. An uncharted signature of dark matter particles produced in association with VV=W^{±}W^{∓} or ZZ pairs from a decay of a dark Higgs boson s is searched for using 139 fb^{-1} of pp collisions recorded by the ATLAS detector at a center-of-mass energy of 13 TeV. The s→V(qq[over ¯])V(qq[over ¯]) decays are reconstructed with a novel technique aimed at resolving the dense topology from boosted VV pairs using jets in the calorimeter and tracking information. Dark Higgs scenarios with m_{s}>160 GeV are excluded.
Measurement of light-by-light scattering and search for axion-like particles with 2.2 nb−1 of Pb+Pb data with the ATLAS detector
We thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; ANID, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS and CEA-DRF/IRFU, France; SRNSFG, Georgia; BMBF, HGF and MPG, Germany; GSRT, Greece; RGC and Hong Kong SAR, China; ISF and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Mor…
Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components
In this study, Rosmarinus officinalis L. essential oil and three of its main components 1,8-cineole (27.23%), α-pinene (19.43%) and β-pinene (6.71%) were evaluated for their in vitro antibacterial activities and toxicology properties. R. officinalis L. essential oil possessed similar antibacterial activities to α-pinene, and a little bit better than β-pinene, while 1,8-cineole possessed the lowest antibacterial activities. R. officinalis L. essential oil exhibited the strongest cytotoxicity towards three human cancer cells. Its inhibition concentration 50% (IC50) values on SK-OV-3, HO-8910 and Bel-7402 were 0.025‰, 0.076‰ and 0.13‰ (v/v), respectively. The cytotoxicity of all the test sampl…
Electron and photon energy calibration with the ATLAS detector using 2015-2016 LHC proton-proton collision data
Artículo realizado por muchos autores. Solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración y los autores que firman como pertenecientes a la UAM
Search for chargino-neutralino production using recursive jigsaw reconstruction in final states with two or three charged leptons in proton-proton collisions at s=13 TeV with the ATLAS detector
A search for electroweak production of supersymmetric particles is performed in two-lepton and three-lepton final states using recursive jigsaw reconstruction, a technique that assigns reconstructed objects to the most probable hemispheres of the decay trees, allowing one to construct tailored kinematic variables to separate the signal and background. The search uses data collected in 2015 and 2016 by the ATLAS experiment in s=13 TeV proton-proton collisions at the CERN Large Hadron Collider corresponding to an integrated luminosity of 36.1 fb-1. Chargino-neutralino pair production, with decays via W/Z bosons, is studied in final states involving leptons and jets and missing transverse mome…
Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study
Editor's Perspective What We Already Know about This Topic Hospital mortality in acute respiratory distress syndrome is approximately 40%, but mortality and trajectory in "mild" acute respiratory distress syndrome (classified only since 2012) are unknown, and many cases are not detected What This Article Tells Us That Is New Approximately 80% of cases of mild acute respiratory distress syndrome persist or worsen in the first week; in all cases, the mortality is substantial (30%) and is higher (37%) in those in whom the acute respiratory distress syndrome progresses Background: Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered …
Measurement of prompt photon production in sNN=8.16 TeV p + Pb collisions with ATLAS
The inclusive production rates of isolated, prompt photons in p+Pb collisions at sNN=8.16 TeV are studied with the ATLAS detector at the Large Hadron Collider using a dataset with an integrated luminosity of 165 nb −1 recorded in 2016. The cross-section and nuclear modification factor RpPb are measured as a function of photon transverse energy from 20 GeV to 550 GeV and in three nucleon–nucleon centre-of-mass pseudorapidity regions, (−2.83,−2.02) , (−1.84,0.91) , and (1.09,1.90) . The cross-section and RpPb values are compared with the results of a next-to-leading-order perturbative QCD calculation, with and without nuclear parton distribution function modifications, and with expectations b…
New loci associated with kidney function and chronic kidney disease
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a meta-analysis of genome-wide association data in 67,093 individuals of European ancestry from 20 predominantly population-based studies in order to identify new susceptibility loci for reduced renal function as estimated by serum creatinine (eGFRcrea), serum cystatin c (eGFRcys) and CKD (eGFRcrea 60 ml/min/1.73 m 2; n = 5,807 individuals with CKD (cases)). Follow-up of the 23 new genome-wide-significant loci (P 5 × 10 8) in 22,982 replication samples identified 13 new loci affecting renal function and CKD (in or…
Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at E beam =4 TeV
Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the FLUKA Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared qua…
2′O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo
2'O-galloylhyperin, an active flavonol glycoside compound with remarkable anti-immune activity, was isolated from Pyrola [P. incarnata Fisch.]. However, the evidence of anti-inflammatory activity in pulmonary diseases was still not convincing. The aim of the present study was (1) to investigate the effect of 2'O-galloylhyperin on LPS-induced acute lung injury in mice, and (2) to identify the mechanisms of attenuation of inflammatory responses. The results demonstrated that 2'O-galloylhyperin significantly reduced LPS-induced inflammation damage in a dose-dependent manner. After LPS challenge, treatment with 2'O-galloylhyperin reduced the production of pro-inflammatory cytokines and chemokin…
Search for the Decay of the Higgs Boson to Charm Quarks with the ATLAS Experiment
A direct search for the standard model Higgs boson decaying to a pair of charm quarks is presented. Associated production of the Higgs and Z bosons, in the decay mode ZH→ℓ+ℓ−c¯c is studied. A data set with an integrated luminosity of 36.1 fb−1 of pp collisions at √s=13TeV recorded by the ATLAS experiment at the LHC is used. The H→c¯c signature is identified using charm-tagging algorithms. The observed (expected) upper limit on σ(pp→ZH)×B(H→c¯c) is 2.7 (3.9+2.1−1.1) pb at the 95% confidence level for a Higgs boson mass of 125 GeV, while the standard model value is 26 fb.
Search for low-mass resonances decaying into two jets and produced in association with a photon using pp collisions at s=13 TeV with the ATLAS detector
A search is performed for localised excesses in dijet mass distributions of low-dijet-mass events produced in association with a high transverse energy photon. The search uses up to 79.8 fb−1 of LHC proton–proton collisions collected by the ATLAS experiment at a centre-of-mass energy of 13 TeV during 2015–2017. Two variants are presented: one which makes no jet flavour requirements and one which requires both jets to be tagged as b-jets. The observed mass distributions are consistent with multi-jet processes in the Standard Model. The data are used to set upper limits on the production cross-section for a benchmark Z′ model and, separately, on generic Gaussian-shape contributions to the mas…
Cholesterol Dependence of Collagen and Echovirus 1 Trafficking along the Novel alpha2beta1 Integrin Internalization Pathway
We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes. Here we show that cholesterol plays a major role not only in the uptake of α2β1 integrin and its ligands but also in the formation of α2 integrin-specific multivesicular bodies (α2-MVBs) and virus infection. EV1 infection and α2β1 integrin internalization were totally halted by low amounts of the cholesterol-aggregating drugs filipin or nystatin. Inhibition of cholesterol synthesis and accumulation of lanosterol after ketoconazole treatment inhibited uptake of collagen, virus and clustered integrin, an…
Search for four-top-quark production in the single-lepton and opposite-sign dilepton final states in pp collisions at s=13 TeV with the ATLAS detector
A search for four-top-quark production, tttt, is presented. It is based on proton-proton collision data with a center-of-mass energy s=13 TeV collected by the ATLAS detector at the Large Hadron Collider during the years 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb-1. Data are analyzed in both the single-lepton and opposite-sign dilepton channels, characterized by the presence of one or two isolated electrons or muons with high-transverse momentum and multiple jets. A data-driven method is used to estimate the dominant background from top-quark pair production in association with jets. No significant excess above the Standard Model expectation is observed. The result i…
Measurements of Higgs boson properties in the diphoton decay channel with 36 fb−1 of pp collision data at s=13 TeV with the ATLAS detector
Properties of the Higgs boson are measured in the two-photon final state using 36.1 fb-1 of proton? proton collision data recorded at ffiffi √s = 13 TeV by the ATLAS experiment at the Large Hadron Collider. Cross-section measurements for the production of a Higgs boson through gluon-gluon fusion, vectorboson fusion, and in association with a vector boson or a top-quark pair are reported. The signal strength, defined as the ratio of the observed to the expected signal yield, is measured for each of these production processes as well as inclusively. The global signal strength measurement of 0.99 ± 0.14 improves on the precision of the ATLAS measurement at √s = 7 and 8 TeV by a factor of two. …