Emergence in 2017-2019 of novel reassortant equine-like G3 rotavirus strains in Palermo, Sicily.

2021

Rotavirus A (RVA) is a major etiologic agent of gastroenteritis in children worldwide. Hospital-based surveillance of viral gastroenteritis in paediatric population in Palermo (Italy) from 2017 onwards revealed a sharp increase in G3P[8] RVAs, accounting for 71% of all the RVAs detected in 2019. This pattern had not been observed before in Italy, with G3 RVA usually being detected at rates lower than 3%. In order to investigate this unique epidemiological pattern, the genetic diversity of G3 RVAs identified during a 16-year long surveillance (2004-2019) was explored by systematic sequencing of the VP7 and VP4 genes and by whole genome sequencing of selected G3 strains, representative of the…

Constitution de corpus thématique : Pour un meilleur suivi du territoire de la Métropole de Montpellier Méditerranée

2021

International audience

Collecte, visualisation et analyse de données viaires géohistoriques

2021

International audience; Les villes sont des territoires complexes qu’il est possible d’appréhender de multiples manières.L’angle d’étude retenu dans la recherche présentée ici est celui morphologique, et plus particulièrement celui lié à la forme des réseaux viaires. Les mécanismes d’évolution de tels réseaux au cours du temps sont complexes et leur modélisation, nécessitant une approche transdisciplinaire, en est à ses premiers pas. La compréhension de leurs dynamiqu es d’évolution comporte de forts enjeux : cela permet de mieux appréhender l’utilisation d’un territoire et son organisation, etégalement de mieux imaginer ses perspectives de développement.Ainsi, Le projet COVADEO.a pour obje…

Enhanced Modelling for Extended Performance Analysis of Interior Permanent Magnet Synchronous Machine Drive fed with Cascaded H-Bridges Multilevel In…

2021

This paper presents a comparative simulation analysis of an Interior Permanent Magnet Synchronous Machine (IPMSM) performance once fed by a traditional three-phase two-level inverter and then using a three-phase five-level Cascaded H-Bridges Multilevel Inverter (CHBMI). For this purpose, an enhanced mathematical model of the IPMSM, that take into account simultaneously saturation, cross-coupling, spatial harmonics and iron loss effects, has been employed. Furthermore, two different PWM modulation strategies have been considered. The study was conducted for several working conditions, evaluating the impact of CHBMI adoption on the IPMSM performance in terms of improved efficiency and torque …

Streaming: ventajas, desafíos y oportunidades de las radiotelevisiones para captar audiencias

2021

La investigación muestra el crecimiento del consumo de streaming en los últimos años y refleja su incremento exponencial a raíz de la pandemia por la Covid 19 en 2020. La base científica cita a los autores más relevantes en esta temática y está avalada por los estudios e informes de organismos oficiales y privados de relevancia internacional. Se estudia el origen del streaming, su evolución y futuro con la ayuda de las nuevas herramientas tecnológicas, como las appsque permiten a los periodistas y al público poder entrar en directo en un informativo. Ello suponenuevas oportunidades de negocio para las radiotelevisiones generalistas creadoras de contenido en España. La investigación muestra …

ΛK femtoscopy in Pb-Pb collisions at √sNN = 2.76 TeV

2021

The first measurements of the scattering parameters of ΛK pairs in all three charge combinations (ΛK+, ΛK−, and ΛK0S) are presented. The results are achieved through a femtoscopic analysis of ΛK correlations in Pb-Pb collisions at √sNN=2.76 TeV recorded by ALICE at the Large Hadron Collider. The femtoscopic correlations result from strong final-state interactions and are fit with a parametrization allowing for both the characterization of the pair emission source and the measurement of the scattering parameters for the particle pairs. Extensive studies with the THERMINATOR 2 event generator provide a good description of the nonfemtoscopic background, which results mainly from collective eff…

DEVELOPMENT AND QUALIFICATION OF BIOANALYTICAL METHODS FOR DEAMIDATED IFNβ-1a AND INVESTIGATION ABOUT THE MECHANISM OF ACTION

2021

Interferon beta-1a (IFNβ-1a) is a recombinant IFNβ with the tradename Rebif involved in several biological activities. Recently, it has been reported that artificial deamidation of IFNb-1a increases its biological response. Given the therapeutical potential, an investigation on the deamidated variant has been carried out via different approaches to discover the mechanism underlying this biological effect. The antiviral and immunomodulatory activity of deamidated cytokine was assessed using two precise and accurate cell-based assays. As expected, deamidated IFNβ-1a showed an increase in the biological response and its canonical pathway and receptor binding affinity were thorough analysed. De…

Assessing Transfer Entropy in cardiovascular and respiratory time series: A VARFI approach

2021

In the study of complex biomedical systems represented by multivariate stochastic processes, such as the cardiovascular and respiratory systems, an issue of great relevance is the description of the system dynamics spanning multiple temporal scales. Recently, the quantification of multiscale complexity based on linear parametric models, incorporating autoregressive coefficients and fractional integration, encompassing short term dynamics and long-range correlations, was extended to multivariate time series. Within this Vector AutoRegressive Fractionally Integrated (VARFI) framework formalized for Gaussian processes, in this work we propose to estimate the Transfer Entropy, or equivalently G…

Electric Vehicles and Psychology, Part 2

2021

This paper presents the main psychological attitudes influencing the transition from conventional ICEV to BEV, and it is the continuance of Electric vehicles and psychology, part 1, [1]. This part faces the range anxiety problem, the risk of explosion of batteries, the autonomous silver vehicles and the experience of driving electric vehicles. If the reader is looking for simple answers, the author does not recommend the subsequent reading, since few paradoxes will be solved.

3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering

2021

The aim of the present study was to fabricate and characterise chitosan scaffolds from animal and fungal sources, with or without gelatine as a co-polymer, and cross-linked to 3-glycidyloxyproply trimethoxysilane (GPTMS) or genipin for application in dental root tissue engineering. Chitosan-based scaffolds were prepared by the emulsion freeze-drying technique. Scanning electron microscopy (SEM) and nano-focus computed tomography (nano-CT) were used to characterise scaffold microstructure. Chemical composition and cross-linking were evaluated by Fourier transform infrared-attenuated total reflectance spectroscopy. Compression tests were performed to evaluate scaffold mechanical properties. S…

On Psychological Aspects about Electric Vehicles, Part 1

2021

The high diffusion of electric vehicles is evidenced by every sector magazine or by the catalog of all the manufacturers inserting incessantly new models. But what are the user's most hidden reactions to the new world of vehicles? Is the user ready for the fifth level of automation (fully automatic driving and absence of the driving position)? The purpose of this paper is to present and discuss the psychological aspects that influence the adoption of electric vehicles by users and beyond. Topics such as the egg and chicken paradox (electric vehicles and charging stations, who was born first) but also performance anxiety (range anxiety) will be addressed. Contradictions and irony will charac…

Dire et vivre son corps en ligne : quelle logique de production de soi pour les porteurs de nævus congénital ?

2021

International audience

Spoken conversational context improves query auto-completion in web search

2021

Web searches often originate from conversations in which people engage before they perform a search. Therefore, conversations can be a valuable source of context with which to support the search process. We investigate whether spoken input from conversations can be used as a context to improve query auto-completion. We model the temporal dynamics of the spoken conversational context preceding queries and use these models to re-rank the query auto-completion suggestions. Data were collected from a controlled experiment and comprised conversations among 12 participant pairs conversing about movies or traveling. Search query logs during the conversations were recorded and temporally associated…

Thermodiffusion anisotropy under a magnetic field in ionic liquid-based ferrofluids

2021

International audience; Ferrofluids based on maghemite nanoparticles (NPs), typically 10 nm in diameter, are dispersed in an ionic liquid (1-ethyl 3-methylimidazolium bistriflimide - EMIM-TFSI). The average interparticle interaction is found to be repulsive by small angle scattering of X-rays and of neutrons, with a second virial coefficient A2 = 7.3. A moderately concentrated sample at Φ = 5.95 vol% is probed by forced Rayleigh scattering under an applied magnetic field (up to H = 100 kA m-1) from room temperature up to T = 460 K. Irrespective of the values of H and T, the NPs in this study are always found to migrate towards the cold region. The in-field anisotropy of the mass diffusion c…

Age-dependent control of collagen-dependent platelet responses by thrombospondin-1 : Comparative analysis of platelets from neonates, children, adole…

2021

Platelet function is developmentally regulated. Healthy neonates do not spontaneously bleed, but their platelets are hypo-reactive to several agonists. The mechanisms underlying immature platelet function in neonates are incompletely understood. This critical issue remains challenging for the establishment of age-specific reference ranges. In this study, we evaluated platelet reactivity of five pediatric age categories, ranging from healthy full-term neonates up to adolescents (11–18 years) in comparison to healthy adults (&gt

DEVELOPMENT OF NONTOXIC BIO-ADHESIVES FOR WET ENVIRONMENTS

2021

Insertion of single-ion magnets based on mononuclear Co(II) complexes into ferromagnetic oxalate-based networks

2021

The 1 : 2 and 1 : 1 Co(ii) complexes of the L ligand (L = 6-(3,5-diamino-2,4,6-triazinyl)2,2'-bipyridine) with formulas [CoII(L)2](ClO4)2·0.5MeCN·Et2O (1) and [CoII(L)(CH3CN)2(H2O)](ClO4)2·MeCN (2) have been prepared. The structural and magnetic characterization of the two compounds shows that they contain octahedral high-spin Co(ii) and present a field-induced slow relaxation of the magnetization. 1 has been inserted into a bimetallic oxalate-based network leading to a novel achiral 3D compound of formula [CoII(L)2][MnIICrIII(ox)3]2·(solvate) (3) exhibiting ferromagnetic ordering below 4.6 K. EPR measurements suggest a weak magnetic coupling between the two sublattices.

Prediction for magnetic moment of the muon informs a test of the standard model of particle physics

2021

A new first-principles computation of the effect that creates most uncertainty in calculations of the magnetic moment of the muon particle has been reported. The results might resolve a long-standing puzzle, but pose another conundrum. Fresh evidence in a longstanding puzzle of particle physics.

Measuring Functional Connectivity of Human Intra-Cortex Regions with Total Correlation

2021

The economy of brain organization makes the primate brain consume less energy but efficiency. The neurons densely wired each other dependent on both anatomy structure connectivity and functional connectivity. Here, I only describe functional connectivity with Functional Magnetic Resonance Imaging (fMRI) data. Most importantly, how to quantitative measure information share or separate among functional brain regions, what’s worse, fMRI data exist large dimensional problems or “curse dimensionality” [1]. However, the multivariate total correlation method can perfectly address the above problems. In this paper, two things measured with the information-theoretic technique - total correlation [2,…

A new 8-oxo-7,8-2 ' deoxyguanosine nanoporous anodic alumina aptasensor for colorectal cancer diagnosis in blood and urine

2021

Many important human diseases, and especially cancer, have been related to the overproduction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxo-dG). This molecule is a product of oxidative stress processes over nucleophilic bases in DNA. In this work, an aptasensor for the rapid, selective and accurate detection of this oncomarker is presented. The aptasensor consists of a nanoporous anodic alumina material loaded with a dye and is functionalized with an aptamer-based "molecular gate". In the presence of target 8-oxo-dG, the capping aptamer displaces from the surface due to the high affinity of the analyte with the capping aptamer, thus inducing delivery of the preloaded fluorescent dye. In co…

Robust entanglement preparation through spatial indistinguishability quantified by entropic measure

2021

Initialization of composite quantum systems into highly entangled states is important to enable their use for quantum technologies. However, unavoidable noise in the preparation stage makes the system state mixed, hindering the achievement of this goal. We address this problem in the context of identical particle systems adopting the operational framework of spatially localized operations and classical communication (sLOCC). After a brief description of the formalism, we define the entanglement of formation for an arbitrary state (pure or mixed) of two identical qubits, valid for both bosons and fermions. We then introduce an entropic measure of spatial indistinguishability as an informatio…

Idioms and fictional orality in Toni Cucarella’s narrative

2021

En aquest article s’estudien les unitats fraseològiques en quatre obres de Toni Cucarella en relació amb l’oralitat ficcional. La tradició d’estudis sobre l’oralitat ficcional analitza els recursos que evoquen l’oralitat en textos escrits o audiovisuals. Entre aquests recursos, en els darrers anys s’ha destacat la importància de certes unitats fraseològiques que són pròpies de la llengua oral i, en aparéixer en textos escrits, evoquen la llengua oral, com un mitjà per caracteritzar de manera versemblant els personatges. Analitzem la recurrència de les unitats fraseològiques i els motius que poden explicar aquesta recurrència. Les unitats fraseològiques més recurrents són les locucions verba…

Is there a role for salivary detoxification enzymes in taste perception?

2021

International audience

RATIONAL DESIGN AND SYNTHESIS OF NOVEL INHIBITORS OF EPIGENETIC TARGET INVOLVED IN CANCER

2021

Nuevas terminaciones para nuevas realidades: performatividad, afiliación y atenuación en la comunidad de habla LGTBI

2021

Este artículo presenta un estudio sobre las terminaciones -i/-is y -e/-es en la comunidad de habla LGTBI. La motivación de esta investigación viene de la representación del género no binario en la lengua española, marcado recientemente por las terminaciones en -e, que además es utilizado para crear un plural inclusivo que evite el masculino genérico. En la misma línea, se han detectado usos, dentro de la comunidad de habla LGTBI, de otro grupo de terminaciones (-i/-is) que parecen anular la distinción de género. Los datos han sido extraídos de una encuesta sociolingüística elaborada por el autor de este trabajo. En la parte sociolingüística se pretende perfilar el tipo de usuario de estas t…

Prácticas devocionales y espacios litúrgicos de Sibila de Fortià, reina de la Corona de Aragón (r. 1377–1387)

2021

Sibila de Fortia se convirtio en esposa del rey Pedro el Ceremonioso y reina de Aragon en unas circunstancias inusuales que supusieron una crisis de legitimidad desde los albores de su reinado. En el presente articulo, se analiza como la reina Sibila, para compensar las debilidades de su pasado y fortalecer su imagen como meritoria ostentadora de la dignidad regia, desarrollo en los primeros anos de su reinado una estrategia de afirmacion personal basada en la demostracion, promocion y proteccion de la religiosidad en la Corona de Aragon en momentos tan significativos como el Cisma de Occidente.

Characterization of key aroma compounds in vegetable proteins foods

2021

International audience; The flavour profile of vegetable proteins food is complex due to the presence of a large number of compounds belonging to different chemical classes. The manufacturing process use many parameters of which temperature plays a role in the generation of volatile compounds.The flavour profile of two vegetable proteins sample (high and low thermal processing) were studied. GC-MS analyses detected and identified 71 aroma compounds (pyrazines, alcohols, ketones, aldehydes) in the two samples. Quantification showed a difference between the two thermal treatments. GC-O analysis described 70 olfactive areas, 39 of which attributed to a chemical compound.

Oral astringency: Effect of ageing and role of saliva

2021

International audience

The GC-PO technique used to evaluate the contribution of odour-active compounds in icewine

2021

International audience

Differences in odour-induced taste enhancement between normal weight and obese populations

2021

International audience

How relational contract theory influence management strategies and project outcomes: a systematic literature review

2021

Despite growing interest in Relational Contracting (RC), few studies have comprehensively investigated the qualities required for a successful RC project. Macneil’s ten norms are principles of behaviour in contracts based on the application of relational contract theory and play an essential role in the formation and agreement of parties and their commitment to means and objectives. In contributing a missing dimension to the RC approach in construction, the purpose of this research is to conduct a systematic review of studies of relational contracting to answer the question: In what ways can the influence of RC theory be observed in the management strategies and outcomes of relational proje…

Student evaluations of the credibility and argumentation of online sources

2021

This study investigated upper secondary school students’ skills in evaluating the credibility and argumentative content of a blog text and a YouTube video. Both sources concerned child vaccination, the blog text opposing and the YouTube video supporting it. Students rated each source as credible, fairly credible or non-credible, justified their ratings, and analyzed the argumentation of both sources. Their justifications were analyzed for trustworthiness and expertise and their argument analyses for identification of the main position of the source and the reasons supporting it. Students’ justification skills proved fairly weak, and they also struggled with recognizing unbalanced argumentat…

The Constant Threat of Zoonotic and Vector-Borne Emerging Tropical Diseases: Living on the Edge

2021

Existence and Relaxation Results for Second Order Multivalued Systems

2021

AbstractWe consider nonlinear systems driven by a general nonhomogeneous differential operator with various types of boundary conditions and with a reaction in which we have the combined effects of a maximal monotone term $A(x)$ A ( x ) and of a multivalued perturbation $F(t,x,y)$ F ( t , x , y ) which can be convex or nonconvex valued. We consider the cases where $D(A)\neq \mathbb{R}^{N}$ D ( A ) ≠ R N and $D(A)= \mathbb{R}^{N}$ D ( A ) = R N and prove existence and relaxation theorems. Applications to differential variational inequalities and control systems are discussed.

GC-APPI-HRMS developments for the analysis of volatile organic compounds

2021

International audience

Indigenous language education in Russia: current issues and challenges

2021

Despite the high number of recognised Indigenous groups who are struggling to maintain their languages, cultures, and identities in Russia, there is little research done on the matters of cultural and linguistic revitalisation. This study sought to address this gap by exploring the views of two Indigenous groups, Karelian and Mari, on the development of their Indigenous languages and educational strategies to protect and revive their languages. The study relied on in-depth one-on-one interviews with 20 participants, ten from each Indigenous group. The findings show that despite older generations’ relative proficiency and interest in their respective Indigenous languages, motivation to maste…