showing 36 of ~574560 from 574555 documents
San-Antonio ou la langue à l’épreuve
2021
International audience; No abstract
Obtaining lignocellulosic biomass-based catalysts and their catalytic activity in cellobiose hydrolysis and acetic acid esterification reactions
2021
Global challenges prompt the world to modify its strategies and shift from a fossil-fuel-based economy to a bio-resource-based one with the production of renewable biomass chemicals. Different processes exist that allow the transformation of raw biomass into desirable bio-based products and/or energy. In this work different biochars that were obtained as a by-product from birch chip fast pyrolysis and carbonization were used as is or chemically/physically treated. These sulfonated carbon catalysts were compared to a commercially available sulfonated styrene-divinylbenzene macroreticular resin (Dowex 50W X8). Characterisation (water content and pH value, FTIR, base titration, element analysi…
The New Gnosis and the Denial of Ontological Differences
2021
The current transhumanist or posthumanist movements continue the thesis of the old gnosis devaluing the creation like something imperfect. Its novelty is to believe in the possibility of overcoming the creation thanks to technology (biotechnology and bionics). The ideology of gender partly anticipates this way of thinking by devaluing the somatic difference between male and female. This denial of the differences then applies to those existing between the human and the non-human (on one side the primates, and on the other the computer). Posthumanism and transhumanism believe that technology will not only overcome the ontological differences, which form the human, but also the so-called extre…
Prosthetically‐Driven Full‐Mouth Implant‐Supported Prostheses Using Guided Surgical Implant Planning with Composite Resin Markers: A Case Report
2021
This report describes a prosthetically-driven implant planning method, guided by the alignment procedures between the cone beam computed tomography, intraoral digital scans, and digitized maxillary and mandibular interim complete dentures using intraoral composite resin markers as a common reference. The markers were attached to the keratinized oral mucosa of the edentulous ridges using cyanoacrylate and kept in place during the digitizing procedures. The technique provides a simpler and more economical alternative to conventional prosthetically-driven static implant planning methods.
Online Closed-Loop Real-Time tES-fMRI for Brain Modulation: Feasibility, Noise/Safety and Pilot Study
2021
AbstractRecent studies suggest that transcranial electrical stimulation (tES) can be performed during functional magnetic resonance imaging (fMRI). The novel approach of using concurrent tES-fMRI to modulate and measure targeted brain activity/connectivity may provide unique insights into the causal interactions between the brain neural responses and psychiatric/neurologic signs and symptoms, and importantly, guide the development of new treatments. However, tES stimulation parameters to optimally influence the underlying brain activity in health and disorder may vary with respect to phase, frequency, intensity and electrode’s montage. Here, we delineate how a closed-loop tES-fMRI study of …
Multiobjective optimization and decision making in engineering sciences
2021
AbstractReal-world decision making problems in various fields including engineering sciences are becoming ever more challenging to address. The consideration of various competing criteria related to, for example, business, technical, workforce, safety and environmental aspects increases the complexity of decision making and leads to problems that feature multiple competing criteria. A key challenge in such problems is the identification of the most preferred trade-off solution(s) with respect to the competing criteria. Therefore, the effective combination of data, skills, and advanced engineering and management technologies is becoming a key asset to a company urging the need to rethink how…
Sófocles, OC 251: el poder del logos
2021
Desde que Reiske modificara el v. 251 de Edipo en Colono sustituyendo λόγος, transmitido por los manuscritos, por λέχος, los editores han aceptado esta corrección salvo escasas excepciones. Restituir λόγος confiere un significado más profundo desde el punto de vista político al verso.
Stable motivic homotopy theory at infinity
2021
In this paper, we initiate a study of motivic homotopy theory at infinity. We use the six functor formalism to give an intrinsic definition of the stable motivic homotopy type at infinity of an algebraic variety. Our main computational tools include cdh-descent for normal crossing divisors, Euler classes, Gysin maps, and homotopy purity. Under $\ell$-adic realization, the motive at infinity recovers a formula for vanishing cycles due to Rapoport-Zink; similar results hold for Steenbrink's limiting Hodge structures and Wildeshaus' boundary motives. Under the topological Betti realization, the stable motivic homotopy type at infinity of an algebraic variety recovers the singular complex at in…
Gendering political conflict: the racialized and dehumanized use of gender on Facebook
2021
Although attacks against gendered others have proliferated around the world, there remains a paucity of research examining the gender-biased climate that normalizes and condones racialization and d...
2FHL
2021
A Generalized Method for High‐Speed Fluorination of Metal Oxides by Spark Plasma Sintering Yields Ta 3 O 7 F and TaO 2 F with High Photocatalytic Act…
2021
A general method to carry out the fluorination of metal oxides with poly(tetrafluoroethylene) (PTFE, Teflon) waste by spark plasma sintering (SPS) on a minute scale with Teflon is reported. The potential of this new approach is highlighted by the following results. i) The tantalum oxyfluorides Ta3 O7 F and TaO2 F are obtained from plastic scrap without using toxic or caustic chemicals for fluorination. ii) Short reaction times (minutes rather than days) reduce the process time the energy costs by almost three orders of magnitude. iii) The oxyfluorides Ta3 O7 F and TaO2 F are produced in gram amounts of nanoparticles. Their synthesis can be upscaled to the kg range with industrial sintering …
Joan Lluís Vives: Emblemes o escortes de l'ànima
2021
Joan Lluís Vives: Emblemes o escortes de l'ànima
First measurement of quarkonium polarization in nuclear collisions at the LHC
2021
The polarization of inclusive J/$\psi$ and $\Upsilon(1{\rm S})$ produced in Pb-Pb collisions at $\sqrt{s_{\rm{NN}}}=5.02$ TeV at the LHC is measured with the ALICE detector. The study is carried out by reconstructing the quarkonium through its decay to muon pairs in the rapidity region $2.5<y<4$ and measuring the polar and azimuthal angular distributions of the muons. The polarization parameters $\lambda_{\theta}$, $\lambda_{\phi}$ and $\lambda_{\theta\phi}$ are measured in the helicity and Collins-Soper reference frames, in the transverse momentum interval $2<p_{\rm T}<10$ GeV/$c$ and $p_{\rm T}<15$ GeV/$c$ for the J/$\psi$ and $\Upsilon(1{\rm S})$, respectively. The polarization parameter…
Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis
2021
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic plaques. Therefore, we studied plasma testosterone levels in relation to gene expression levels in atherosclerotic plaque tissue of men with advanced atherosclerotic disease.Methods: Plasma testosterone levels were measured in 203 men undergoing carotid endarterectomy. The corresponding atherosclerotic plaque tissue was used for RNA sequencing. First, we assessed how often the androgen receptor gene was expressed in the plaque. Second, correlati…
Valencia honouring Juan Luis Vives
2021
Valencia honouring Juan Luis Vives. “Quousque tandem, Valentia Edetanorum, patiere maculam istam?”
¿Es Juan Luis Vives el retratado en "Un humanista"?
2021
¿Es Juan Luis Vives el retratado en "Un humanista"?
Synthesis, X-ray Structure Determination, and Comprehensive Photochemical Characterization of (Trifluoromethyl)diazirine-Containing TRPML1 Ligands
2021
Potential (trifluoromethyl)diazirine-based TRPML1 ion channel ligands were designed and synthesized, and their structures were determined by single-crystal X-ray diffraction analysis. Photoactivation studies via 19F NMR spectroscopy and HPLC-MS analysis revealed distinct kinetical characteristics in selected solvents and favorable photochemical properties in an aqueous buffer. These photoactivatable TRPML activators represent useful and valuable tools for TRPML photoaffinity labeling combined with mass spectrometry.
2-Sulfoximidoyl Acetic Acids from Multicomponent Petasis Reactions and Their Use as Building Blocks in Syntheses of Sulfoximine Benzodiazepine Analog…
2021
Upon application of a multicomponent Petasis reaction, a broad range of NH-sulfoximines and boronic acids react with glyoxalic acid to afford the corresponding 2-substituted acetic acids with N-bound sulfoximidoyl groups. The protocol features excellent yields under ambient, metal-free conditions and short reaction times. Furthermore, the applicability of 2-sulfoximidoyl acetic acids as building blocks for synthesizing sulfoximine-based benzodiazepine analogues was demonstrated.
Deep Networks for Collaboration Analytics : Promoting Automatic Analysis of Face-to-Face Interaction in the Context of Inquiry-Based Learning
2021
Scholars have applied automatic content analysis to study computer-mediated communication in computer-supported collaborative learning (CSCL). Since CSCL also takes place in face-to-face interactions, we studied the automatic coding accuracy of manually transcribed face-to-face communication. We conducted our study in an authentic higher-education physics context where computer-supported collaborative inquiry-based learning (CSCIL) is a popular pedagogical approach. Since learners’ needs for support in CSCIL vary in the different inquiry phases (orientation, conceptualization, investigation, conclusion, and discussion), we studied, first, how the coding accuracy of five computational models…
Educación performativa musical: herramientas para la investigación
2021
espanolEste articulo pretende dotar de herramientas al docente para que aborde la realidad de la clase practica instrumental. A traves de la metodologia de complementacion cuantitativa y cualitativa, se observa como esta resulta la solucion mas indicada para este tipo de investigaciones. A partir de una reflexion sobre la clase musical instrumental y la investigacion en didactica de los instrumentos, el cuestionario se revela como la herramienta mas completa para conocer la actitud del profesorado acerca de la praxis docente. Repasando algunas investigaciones sobre educacion performativa se aportan ejemplos que permitan a los profesores enfrentarse a los retos que supone la educacion musica…
Insolite : la nuit, ils carottent les sols des couloirs de tram
2021
National audience; L’opération a duré de 23 heures à 2 h 30, dans la nuit de mercredi à jeudi. Des chercheurs de l’Institut national de recherches agronomiques de Dijon ont prélevé des sols pour analyser et découvrir les organismes qu’ils abritent. Le référentiel, en cours d’élaboration, est une première à l’échelle européenne.
Présentation du projet Burgundia Humanistica
2021
International audience; No abstratc
false
2021
The binding of natural ligands and synthetic drugs to the P2Y12 receptor is of great interest because of its crucial role in platelets activation and the therapy of arterial thrombosis. Up to now, all computational studies of P2Y12 concentrated on the available crystal structures, while the role of intrinsic protein dynamics and the membrane environment in the functioning of P2Y12 was not clear. In this work, we performed all-atom molecular dynamics simulations of the full-length P2Y12 receptor in three different membrane environments and in two possible conformations derived from available crystal structures. The binding of ticagrelor, its two major metabolites, adenosine diphosphate (ADP)…
The influence of lipid content and taxonomic affiliation on methane and carbon dioxide production from phytoplankton biomass in lake sediment
2021
A presentation of Robert Tally Jr., Spatiality. Routledge, 2013.
2021
National audience
Muscle Function Differences between Patients with Bulbar and Spinal Onset Amyotrophic Lateral Sclerosis. Does It Depend on Peripheral Glucose?
2021
Background: One of the pathogenic mechanisms of ALS disease is perturbed energy metabolism particularly glucose metabolism. Given the substantial difference in the severity and the prognosis of the disease, depending on whether it has a bulbar or spinal onset, the aim of the study was to determine metabolic differences between both types of ALS, as well as the possible relationship with muscle function. Materials and Methods: A descriptive, analytical, quantitative, and transversal study was carried out in hospitals and Primary Care centers in the region of Valencia, Spain. Fasting glucose and alkaline phosphatase (AP) levels in venous blood, muscle percentage, fat percentage, muscle streng…
Current Management of Post-radical Prostatectomy Urinary Incontinence
2021
Frontiers in surgery 8, 647656 (2021). doi:10.3389/fsurg.2021.647656 special issue: "Sequelae of Prostate Cancer Therapy: Avoidance strategies and management options / Edited by: clemens M. Rosenbaum, Felix Campos-Juanatey, Luis A. Kluth"
Reputation and financial reporting in Finnish public organizations
2021
PurposeThis article analyzes the links between financial reports and reputation in the context of Finnish public sector organizations. In general, the paper discusses the accounting treatment of intangible and tangible assets and the quality and relevance of public sector financial reporting.Design/methodology/approachFor data, we combine three data sets: financial statement information of eight anonymous Finnish public organizations, the results of a reputation survey among their key stakeholders (N = 914) and a sample of the social media sentiment around the organizations.FindingsOur findings suggest that a decrease in spending and, surprisingly in the nonprofit sector, an increase in the…
Boosting Biomass Quantity and Quality by Improved Mixotrophic Culture of the Diatom Phaeodactylum tricornutum
2021
Diatoms are photoautotrophic unicellular algae and are among the most abundant, adaptable, and diverse marine phytoplankton. They are extremely interesting not only for their ecological role but also as potential feedstocks for sustainable biofuels and high-value commodities such as omega fatty acids, because of their capacity to accumulate lipids. However, the cultivation of microalgae on an industrial scale requires higher cell densities and lipid accumulation than those found in nature to make the process economically viable. One of the known ways to induce lipid accumulation in Phaeodactylum tricornutum is nitrogen deprivation, which comes at the expense of growth inhibition and lower c…
Do current levels of UV‐B radiation affect vegetation? The importance of long‐term experiments
2021
Binary Hamming codes and Boolean designs
2021
AbstractIn this paper we consider a finite-dimensional vector space $${\mathcal {P}}$$ P over the Galois field $${\text {GF}}(2),$$ GF ( 2 ) , and the family $${\mathcal {B}}_k$$ B k (respectively, $${\mathcal {B}}_k^*$$ B k ∗ ) of all the k-sets of elements of $$\mathcal {P}$$ P (respectively, of $${\mathcal {P}}^*= {\mathcal {P}} \setminus \{0\}$$ P ∗ = P \ { 0 } ) summing up to zero. We compute the parameters of the 3-design $$({\mathcal {P}},{\mathcal {B}}_k)$$ ( P , B k ) for any (necessarily even) k, and of the 2-design $$({\mathcal {P}}^{*},{\mathcal {B}}_k^{*})$$ ( P ∗ , B k ∗ ) for any k. Also, we find a new proof for the weight distribution of the binary Hamming code. Moreover, we…
Reconciling conflicting predictions about transience and persistence of management concepts in management fashion theory and new institutionalism
2021
PurposeAlthough drawing from neoinstitutional theoretical apparatus and ontology, management fashion theory is understood as a theory that explains the transitory nature of popular ideas and practices while institutional theory explains their stabilization, persistence and further institutionalization. In a nutshell, it seems that being opposed to each other, these two theories describe and predict different, incommensurable diffusion trajectories and organizational behaviour patterns. The purpose of this paper is to unify these two competing perspectives.Design/methodology/approachThis paper makes an attempt toward further unification of management fashion theory with new institutionalism …
Search for Axionlike Dark Matter Using Solid-State Nuclear Magnetic Resonance.
2021
Physical review letters 126(14), 141802 (2021). doi:10.1103/PhysRevLett.126.141802
Il dovere di riservatezza dei dipendenti delle organizzazioni internazionali
2021
Apesar das diferenças estruturais e regulatórias que caracterizam as organizações internacionais individuais, a doutrina de hoje é unânime em afirmar a capacidade de cada organização de criar seu próprio sistema jurídico interno. A relação de trabalho dentro dessas organizações reproduz claramente muitas das características da relação de trabalho internas a um Estado e, embora haja uma falta de regras internacionais uniformes sobre o emprego, e cada organização internacional tenha absoluta autonomia jurídica e administrativa, é possível identificar certas obrigações e direitos dos funcionários internacionais que se replicam, de forma ampla e homogênea, na maioria das organizações. O artigo …
Real-World Hypertension Prevalence, Awareness, Treatment, and Control in Adult Diabetic Individuals: An Italian Nationwide Epidemiological Survey
2021
Introduction: Hypertesion is the leading cause of morbidity and mortality, worldwide, and its prevalence has been increasing in several countries, including Italy. Aims: To assess hypertension prevalence, awareness, treatment, and control in a real-world sample of adults with self-reported diabetes compared with nondiabetic individuals. Methods: Following the 2018 World Hypertension Day, a nationwide, cross-sectional epidemiological survey on cardiovascular risk factors (“Abbasso la Pressione!”) in 3956 Italian pharmacies enrolled 47217 self-presenting volunteers (≥ 18 years). Participants underwent standardized blood pressure (BP) measurements and answered a questionnaire on cardiovascular…