showing 36 of ~574560 from 574555 documents

Porous structure of highly crosslinked styrene‐divinylbenzene copolymers

1984

Porous structure of two series of styrene (S)‐divinylbenzene (DVB) copolymers has been studied. The copolymers were prepared by suspension copolymerization of the monomers (50 wt.‐% of DVB) in the presence of heptane‐toluene mixtures as inert diluents. The fraction of diluents in the polymerization system or heptane: toluene ratio was changed. Both the pore volume and specific surface area increase as does dilution or the fraction of heptane in diluents, but the measured values change depending on sample pretreatment. A mechanism of structure built up is discussed and the porosity changes explained in terms of a microsyneresis of inhomogeneous S‐DVB copolymer gel.

Macromolecular Materials and Engineering

Mapy mentalne i ich zastosowanie w badaniach geograficznych

1984

W artykule omówiono jeden z podstawowych sposobów analizy i prezentacji preferencji przestrzennych ludzi w badaniach geograficznych, jakim są tzw. mapy mentalne. Pojęcie to generalnie odnoszące się do obrazu przestrzeni geograficznej w świadomości człowieka, jest w literaturze rozumiane i stosowane wieloznacznie, co między innymi starano się przedstawić w artykule. Wśród innych przykładów zaprezentowano też mapy tego typu, opracowane dla obszaru Polski, będące wyrazem preferencji przestrzennych grup ludzi, reprezentujących różne regiony naszego kraju.

Czasopismo Geograficzne

El complejo de vegetación de las paleodunas de la dehesa de la Albufera de Valencia: Un ejemplo de paraserie

1984

Se hace una síntesis de la vegetación de las paleodunas de la Dehesa de la Albufera de Valencia y se caracteriza la paraserie sabulícola de la Phillyrea angustifolia (Phillyreo angustifoliae-Rhamneto angustifoliae-parasigmetum).

DehesasUNESCO::HISTORIAGeografíaUNESCO::HISTORIA::Historia por épocas::Historia antiguaGeociencias. Medio ambienteVegetaciónEcosistemasClima mediterráneo:HISTORIA::Historia por épocas::Historia antigua [UNESCO]AlbuferasGrupo BDunas costeras:HISTORIA [UNESCO]Fitogeografía

Intense source of slow positrons from pulsed electron accelerators

1984

A pulsed LINAC is used for pair production in a tantalum target of 2.5 radiation lengths in an energy range from 80 to 260 MeV. Several well-annealed tungsten vanes are placed immediately behind the target and thermalize a small fraction of the fast positrons. The slow positrons are extracted from the target region and magnetically guided over a distance of 17 m to the detector at the end of an S-shaped solenoid. Two Nal detectors with well-known detection efficiency are used to register the 511 keV annihilationγ-rays. To reduce pile-up effects 50 mm of Pb were placed in front of the detectors. At an average electron current of 1 μA we could detect about 107 slow positrons per second. The p…

PhysicsRange (particle radiation)Physics and Astronomy (miscellaneous)Physics::Instrumentation and DetectorsGeneral EngineeringParticle acceleratorSolenoidGeneral ChemistryElectronRadiationLinear particle acceleratorlaw.inventionNuclear physicsPositronPair productionlawPhysics::Accelerator PhysicsHigh Energy Physics::ExperimentGeneral Materials ScienceAtomic physicsApplied Physics A Solids and Surfaces

Exact PWBA virtual photon spectrum for a(γv, D)R

1984

PhysicsHardware and ArchitectureSpectrum (functional analysis)General Physics and AstronomyVirtual particleComputational physicsComputer Physics Communications

Vergleichende tierexperimentelle Untersuchungen zur Knochenreaktion nach Implantation von titanplasmaflamebeschichteten Titanimplantaten und Implanta…

1984

Die Entwicklung zementlos fixierbarer Endoprothesen in der Orthopadie und die Verbesserung der Langzeitprognose dentaler Implantate hat zu einer Vielzahl neuer Implantatwerkstoffe gefuhrt. In einer parallelen tierxperimentellen Untersuchung konnte an einer durch Plasmaflamebeschichtung Oberflachenrauhen Titanmodifikation ebenso wie an einer Glaskeramik mit poroser Oberflachenstruktur nach 8 Wochen im Kaninchenfemur inniger Knochenkontakt nachgewiesen werden. An Explantaten belasteter IMZ-Implantate aus gleichem Titan wegen gingivaler Entzundung haben wir auch beim Menschen einen innigen Implantat-Knochen-Kontakt ohne bindegewebige Trennschicht nachweisen konnen (Abb. 1).

España y la OTAN

1984

ModernizaciónProgresoAMELAVidal-Beneyto JoséPOLÍTICAEntrevistasOTANRelaciones Internacionales

Co-Rotating Beams of Antiprotons and H- in LEAR and High Resolution Spectroscopy of pp̄ Atoms in Flight

1984

Beams of pp atoms flighting in vacuum with adjustable velocity have been proposed to study the spectroscopy of protonium atoms with high energy resolution (Ae/E down to 10-5) by using differential absorber foils and conventional X-ray detectors for emission spectroscopy and fixed frequency high power radiation sources for induced spectroscopy1. This aproach would lead to an improvement by more than two orders of magnitude versus the possibilities of “conventional” experiments in the field of protonium planned at LEAR2, and would give ways to measure with high accuracy effects of electromagnetic and strong interactions on the atomic levels of protonium.

PhysicsField (physics)ProtoniumAntiprotonEmission spectrumRadiationAtomic physicsSpectroscopyOrder of magnitudeExotic atom

Methods for the rapid detection, isolation and sequence determination of “peptaibols” and other aib-containing peptides of fungal origin. I. Gliodeli…

1984

A rapid and simple detection procedure of Aib-containing “peptaibol” polypeptide antibiotics (mycotoxins) in fungal culture broths is described which employs alkylsilica (Sep-Pak®) cartridges for a selective enrichment, and the utilization of the unusualα-aminoisobutyric acid (Aib) and amino alcohols as specific marker constituents, which are easily detectable in total hydrolysates. Preparative isolations from fermentation broths is facilitated by adsorber resin (XAD) column chromatography, and purification of crude isolates is achieved by silica gel- and sephadex LH-20 chromatography. Preparative HPLC using spherical, totally porous ODS-bonded phases enables the isolation of uniform peptid…

ChromatographyResolution (mass spectrometry)Silica gelOrganic ChemistryClinical BiochemistryPeptaibolFast atom bombardmentMass spectrometryBiochemistryAnalytical ChemistryComplete sequencechemistry.chemical_compoundColumn chromatographychemistrySephadexChromatographia

Photobiology in space: An experiment on Spacelab I

1984

The joint European/US Spacelab Mission I, scheduled for October 1983 for a 9 day lasting Earth-orbiting flight, provides a laboratory system for various disciplines of science, including exobiology. On the pallet, in the experiment ES 029 "Microorganisms and Biomolecules in Space Hard Environment" 316 dry samples of Bacillus subtilis spores will be exposed to space vacuum and/or selected wavelenghs of solar UV radiation. After recovery action spectra of inactivation, mutation induction, reparability and photochemical damage in DNA and protein will be determined. The results will contribute to the understanding of the mechanism of the increased UV sensitivity of bacterial spores in vacuo and…

DNA BacterialSpores BacterialPhysicsRecovery - actionExtraterrestrial EnvironmentUltraviolet RaysGeneral MedicineSpace FlightAgricultural and Biological Sciences (miscellaneous)United StatesUv sensitivityAstrobiologyEuropeBacterial ProteinsPhotobiologySpace and Planetary ScienceMutationGeneral Earth and Planetary SciencesInterplanetary spaceflightEcology Evolution Behavior and SystematicsBacillus subtilisGeneral Environmental ScienceMutation inductionOrigins of Life

Dissidència política i repressió social al Pais Valencià a mitjan segle XVII

1984

CON EL PRESENTE TRABAJO ABORDAMOS LA PROBLEMATICA DE LA PROGRESIVA INTEGRACION DEL PAIS VALENCIANO EN LOS DESIGNIOS DE LA MONARQUIA HISPANICA. PONEMOS DE RELIEVE COMO LA DISIDENCIA POLITICA DE LAS CAPAS DIRIGENTES VALENCIANAS (PROTAGONISTAS DE TACTICAS MAFIOSAS, CONEXAS CON EL BANDOLERISMO Y ENCAMINADAS A SEGUIR CONSERVANDO SU PODER POLITICO Y ECONOMICO) VA A SER OBJETO DE UNA FUERTE REPRESION, SO CAPA DE RESTAURAR EL ORDEN PUBLICO. TODO ELLO EN UNOS MOMENTOS GRAVES PARA LA CORONA: LA GUERRA DE CATALUÑA, PARA LA QUE SE NECESITABA UNA INCONDICIONAL AYUDA VALENCIANA Y POR TANTO UNA SITUACION INTERNA DE PROBLEMAS Y RESISTENCIAS.

Oposición políticaBandolerismoGuerra de CataluñaUNESCO::HISTORIA::Historia por épocas::Historia antiguaMonarquíaAutonomía políticaRepresión política:HISTORIA::Historia por épocas::Historia antigua [UNESCO]OligarquíaCrisis política

H2-Antihistaminika, 18. Mitt. 5,6-Alkylsubstituierte 4-Pyrimidinone mit H2-antihistaminischer Wirkung

1984

5,6-Alkylsubstituierte 2-{2-[(5-Methyl-4-imidazolyl)-methylthio]-ethylamino}-4-pyrimidinone wurden dargestellt und auf ihre H2-antihistaminische Wirksamkeit untersucht. H2-Antihistaminics, XVIII: 5,6-Alkyl-4-pyrimidones with H2-Antihistaminic Activity 5,6-Alkyl-2-{2-[(5-methyl-4-imidazolyl)methylthio]ethylamino}-4- pyrimidones were prepared and tested for their H2-antihistaminic activities.

chemistry.chemical_compoundPyrimidinonesChemistryStereochemistryDrug DiscoveryLactamPharmaceutical ScienceBiological activityArchiv der Pharmazie

El utillaje neolítico en sílex del litoral mediterráneo peninsular

1984

lcsh:CHumanidadeslcsh:Archaeologylcsh:CC1-960lcsh:Auxiliary sciences of historyUNESCO::HISTORIA::Ciencias auxiliares de la historia::ArqueologíaHistoria:HISTORIA::Ciencias auxiliares de la historia::Arqueología [UNESCO]

IL TRICOBEZOARIO IN ETA' PEDIATRICA: Descrizione di un caso a localizzazione gastrica

1984

The Authors report a case of gastric thricobezoar in paediatric age wuth its diagnostic program. Thr role of ultrasonografic and endoscopic methods are evaluated.

Settore MED/20 - Chirurgia Pediatrica E Infantilethricobezoar in paediatrc age.

La stérilité male cytoplasmique du tournesol (Helianthus annuus L.) : caractérisation des ADN chloroplastiques

1984

Notice présente dans BelInra (https://belinra.inra.fr/gestion/catalog.php?categ=isbd&id=83503); il s'agit d'un type de produit dont les métadonnées ne correspondent pas aux métadonnées attendues dans les autres types de produit : DISSERTATION; La stérilité male cytoplasmique du tournesol (Helianthus annuus L.) : caractérisation des ADN chloroplastiques

amélioration génétiquechloroplaste adncytoplasmic male sterilitysunflowerstérilité mâle cytoplasmiquepurificationrefininghelianthus annuusmarqueur génétiquesolvent free microwave extraction (sfem)physical map[SDV.BDLR]Life Sciences [q-bio]/Reproductive Biologysunflowersplante industrielleoléoprotéagineuxrestriction enzymestournesol[ SDV.BDLR ] Life Sciences [q-bio]/Reproductive Biologycarte de restrictionextractionprotein-oil cropenzyme de restriction[SDV.BDLR] Life Sciences [q-bio]/Reproductive Biology

Darstellung, Kristallstruktur und Wirkung von 2-Methyl-3-(4-oxo-3-phenyl-thiazolidin-2-ylidenamino)-4-(3H)-chinazolinon

1984

Quinazolinones. 1. Preparation, crystal structure and action of 2-methyl-3-(4-oxo-3-phenyl-thiazolidine-2-ylidenamino)-4-(3H)- quinazolinone.

chemistry.chemical_compoundchemistryBicyclic moleculeStereochemistryDrug DiscoveryX-ray crystallographyLactamPharmaceutical ScienceMoleculeBiological activityCrystal structureQuinazolinoneArchiv der Pharmazie

Perkutane Nephrolithotomie — klinische Erfahrungen

1984

Nach perkutaner Nephrostomie konnen neben diagnostischen Masnahmen 4 therapeutische Verfahren zur Anwendung kommen: Die Behandlung von Strikturen oder Stenosen im Bereich des Harnleiterabganges [1], die transrenale Uretersplintung [2], die transrenale Ureterokklusion [3] und die Steinentfernung [4]. Das letztere Verfahren hat sich mit etwa 2 000 weltweit durchgefuhrten Behandlungen etabliert [5].

Collagen of slow twitch and fast twitch muscle fibres in different types of rat skeletal muscle

1984

The appearance of collagen around individual fast twitch (FT) and slow twitch (ST) muscle fibres was investigated in skeletal muscles with different contractile properties using endurance trained and untrained rats as experimental animals. The collagenous connective tissue was analyzed by measuring hydroxyproline biochemically and by staining collagenous material histochemically in M. soleus (MS), M. rectus femoris (MRF), and M. gastrocnemius (MG). The concentration of hydroxyproline in the ST fibres dissected from MS (2.72 +/- 0.35 micrograms X mg-1 d.w.) was significantly higher than that of the FT fibres dissected from MRF (1.52 +/- 0.33 micrograms X mg-1 d.w.). Similarly, the concentrat…

Malemedicine.medical_specialtyNitrogenPhysiologyConnective tissueTonic (physiology)Hydroxyprolinechemistry.chemical_compoundEndurance trainingPhysiology (medical)Internal medicinemedicineAnimalsOrthopedics and Sports MedicinePerimysiumPhysical Education and TrainingHistocytochemistryMusclesPublic Health Environmental and Occupational HealthSkeletal muscleRats Inbred StrainsGeneral MedicineAnatomyEndomysiumRatsHydroxyprolinemedicine.anatomical_structureEndocrinologychemistryConnective TissueCollagenmedicine.symptomMuscle ContractionMuscle contractionEuropean Journal of Applied Physiology and Occupational Physiology

Rinnakkaislaskenta osittaisdifferentiaaliyhtälöiden numeerisessa ratkaisemisessa

1984

difflaskentarinnakaislaksenta

Noticias de tres títulos universitarios de la Corona de Aragón (siglo XVIII)

1984

:HISTORIA::Historia moderna [UNESCO]HumanidadesUNESCO::HISTORIA::Historia modernaHistoria

Computertomographie bei Nierenverletzungen

1984

Problematisches Ziel der zahlreichen klinischen Klassifikationen des Nierentraumas ist die indirekte pratherapeutische Erfassung des pathologisch-anatomischen Substrates durch verschiedene diagnostische Masnahmen, um daraus ein zuverlassiges Therapiekonzept auch fur den Einzelfall ableiten zu konnen. Je genauer der pathologisch-anatomische Befund beschrieben werden kann, desto zielgerichteter kann die Therapie sein. Nach Lutzeyer [1] ist es aber immer ein hypothetischer Versuch, der erst retrospektiv durch feindiagnostische Masnahmen oder den operativen Eingriff seine Klassifikationsbestatigung erfahren kann. Das kennzeichnet die Schwache der diagnostischen Verfahren ebenso, wie die von Cas…

Textural, chemical and isotopic variations induced by hydrothermal fluids on mesozoic limestones in northwestern Sicily

1984

The results are given of textural and compositional investigations carried out on carbonate materials outcropping in various localities in northwestern Sicily where fluorite, barite and calcite mineralizations of hydrothermal origin occur. Observation of the textural features indicate variations in the degree of calcite recrystallization and silicification that appear to be more marked in rocks that show more evident effects of mineralization. The geochemical behaviour of the minor elements indicate variations in chemical composition (increase of Mn, Fe, and Sr and removal of Mg) as a result of interactions between mineralizing fluids and host-rocks. Comparison between the isotopic composit…

CalciteMineralization (geology)OutcropGeochemistryMineralogyFluoriteHydrothermal circulationchemistry.chemical_compoundGeophysicschemistryGeochemistry and PetrologyCarbonateEconomic GeologyChemical compositionGeologyWall rockMineralium Deposita

Gas chromatography of homologous esters

1984

Abstract The gas chromatographic retention behaviour of the butanoyl and 2-, 3- and 4-chlorobutanoyl esters of C 3 —C 5 saturated aliphatic branched-chain and unsaturated C 3 —C 6 alcohols on SE-30 and OV-351 glass capillary columns operated iso-thermally at several temperatures is reported. Retention index increments at 80, 120 and 160°C show the effects of chain branching and the olefinic and acetylenic unsaturation in the alkyl chain and the effect of the position of the chlorine substituent in the acyl chain. The results are compared with the behaviour of the corresponding n -alkyl esters and the chlorinated propanoyl esters.

chemistry.chemical_classificationDegree of unsaturationChromatographyCapillary actionOrganic ChemistryChloroacetateschemistry.chemical_elementGeneral MedicineBranching (polymer chemistry)BiochemistryIsothermal processAnalytical ChemistryHomologous serieschemistry.chemical_compoundCapillary columnchemistryAcyl chainChlorineOrganic chemistryKovats retention indexGas chromatographyMethyleneChlorine substituentAlkylJournal of Chromatography A

Early deaths in acute lymphoblastic leukemia (ALL): results of the Italian Pediatric Cooperative Group for Therapy of Acute Leukemia (AIL-AIEOP).

1984

In this retrospective multicentric study, we report on early deaths (ie, those that occurred during the first month of treatment) in a total of 943 newly diagnosed ALL pediatric patients registered from 1976 to 1981 at 21 centers of the AIL-AIEOP. Objectives of this study were as follows: (1) to verify the incidence and the cause of early death in a wide population of children with ALL and (2) to elucidate factors associated with early death and therefore to identify “high-risk” groups of patients. Out of the 943 ALL patients, 39 (4.1%) early deaths were registered. Main causes were infection, 20 patients (51.3%); hemorrhage, 11 patients (28.3%); uric acid nephropathy, 2 patients (5.1%); ca…

Cancer ResearchPediatricsmedicine.medical_specialtyAdolescentHeart DiseasesLymphoblastic LeukemiaPopulationEarly deathHemorrhageInfectionsMediastinal NeoplasmsNephropathyAntineoplastic Combined Chemotherapy ProtocolsmedicineHumanseducationChildRetrospective Studieseducation.field_of_studyAcute leukemiabusiness.industryIncidence (epidemiology)Age FactorsMediastinumInfantmedicine.diseasePrognosisLeukemia Lymphoidmedicine.anatomical_structureOncologyChild PreschoolPediatrics Perinatology and Child HealthSyndrome of inappropriate antidiuretic hormone secretionKidney DiseasesbusinessMedical and pediatric oncology

Etude de la phytotoxicité de quelques biscarbamates, phényl-4 allophanates et dioxa-1,3 cyclohexanes

1984

*INRA URD BP 86510 21065 Dijon cedex (FRA) Diffusion du document : INRA URD BP 86510 21065 Dijon cedex (FRA) Diplôme : Dr. Ing.

[SDV] Life Sciences [q-bio][SDV]Life Sciences [q-bio]BIOLOGIECHIMIE

Gas-liquid chromatographic analyses

1984

A mixture of all nine chlorinated 4-hydroxybenzaldehydes and the parent homologue was separated on a non-polar SE-30 capillary column using various isothermal and temperature-programmed operating conditions. The relative retention data for the compounds are given and the retention indices together with the retention index increments for each position of chlorine substitution are examined. The retention order 3-Cl<parent<2,5-di-Cl<2,3-di-Cl<3,5-di-Cl<2-Cl<2,3,5-tri-Cl<2,3,6-tri-Cl<2,6-di-Cl<tetra-Cl isomer obtained indicates that the effect of the position of substitution on the retention behaviour is greater than that of the number of chlorine atoms. The retention is maximal with 2-Cl and 2…

ChromatographyChemistryOrganic Chemistrychemistry.chemical_elementGeneral MedicineBiochemistryIsothermal processAnalytical ChemistryCapillary columnStationary phaseChlorineKovats retention indexNon polarGas chromatographyGas liquid chromatographicJournal of Chromatography A

Therapieform und Spätergebnisse der stadienorientierten Behandlung stumpfer Nierentraumen

1984

In der retrospektiven Studie untersuchten wir 130 Patienten, die wegen eines stumpfen Nierentraumas behandelt wurden Anhand der vorliegenden Unterlagen wurde retrospektiv das Trauma klassifiziert als leicht (Kontusion, Laceration), mittelschwer (Parenchymeinris, groses perirenales Hamatom) und schwer (Berstung, Nierenstielabris).

Use of chlorophyll fluorescence induction kinetics to study translocation and detoxication of DCMU-type herbicides in plant leaves

1984

Transient levels of the fluorescence induction rise were used to quantify partial photosynthesis inhibition by DCMU -type herbicides in whole leaves. Assays in different crop or weed species showed a good accuracy in measurements (generally, variation was lower than 5%). This technique was applied to the problem of varietal selectivity of wheat towards chlortoluron.

0106 biological sciences[SDV]Life Sciences [q-bio]food and beveragesDCMUChromosomal translocation04 agricultural and veterinary sciencesMETHODE PAR CHIMILUMINESCENCEInduction kineticsPhotosynthesis01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyDetoxication[SDV] Life Sciences [q-bio]010602 entomologychemistry.chemical_compoundchemistryBotanyChlortoluron040103 agronomy & agriculture0401 agriculture forestry and fisheriesWeedChlorophyll fluorescenceComputingMilieux_MISCELLANEOUS

L'insertion professionnelle des diplômés en France

1984

International audience

Diplômé de l'enseignement supérieurChômageDéclassement professionnelInsertion professionnelle des diplômés de l'enseignement supérieur[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationInsertion professionnelleFranceComputingMilieux_MISCELLANEOUSEnseignement supérieur

La triquinosis en la España del siglo XIX a través de la obra de Antonio Suárez: De las trichinas y de la trichinosis en España

1984

Estudi sobre la malaltia de la triquinosi a Espanya en el segle XIX. Assenyalen que la incidència de la triquinosi a Espanya va ser nul·la, en un primer moment, degut, possiblement, a la manera diferent d'encebar als porcs. Els autors se centren en l'obra d'Antonio Suárez “De las trichinas y de la trichinosis en España” publicada en 1877. //. Estudio sobre la enfermedad de la triquinosis en España en el siglo XIX. Señalan que la incidencia de la triquinosis en España fue nula, en un primer momento, debido, posiblemente, al modo diferente de cebar a los cerdos. Los autores se centran en la obra de Antonio Suárez “De las trichinas y de la trichinosis en España” publicada en 1877.

triquinosihistoria de la medicinatriquinosishistòria de la medicina:CIENCIAS MÉDICAS ::Patología::Parasitología [UNESCO]UNESCO::HISTORIA::Historia por especialidades::Historia de la medicinaparasitología:HISTORIA::Historia por especialidades::Historia de la medicina [UNESCO]parasitologiaUNESCO::CIENCIAS MÉDICAS ::Patología::Parasitología

Platelet Activity and Blood Lipid Changes in Diabetes Mellitus

1984

An altered platelet function can often be found in diabetes mellitus (2, 3, 4, 10, 13, 16, 17, 23, 24). Several studies have pointed towards an increased sensitivity of platelets to ADP induced aggregation (3, 6, 23) in diabetic patients; this phenomenon can also be found in diabetics without apparent vasculopathy and in subjects with altered glucose tolerance (3, 23).

medicine.medical_specialtybusiness.industryfood and beveragesBlood lipidsDiabetic retinopathyDiabetic angiopathymedicine.diseaseMalondialdehydechemistry.chemical_compoundEndocrinologychemistryInternal medicineDiabetes mellitusmedicinePlateletPlatelet activationbusinessProstaglandin endoperoxide

José Vidal-Beneyto, sociólogo del conocimiento

1984

Sobre José Vidal-Beneyto: Reseñas críticas y referencias a la obra de Vidal-BeneytoCEISACulturaConocimientoJOSÉ VIDAL-BENEYTOVidal-Beneyto JoséSOCIOLOGÍAInvestigaciónAcciones: Acciones de una vida: Sociología y nuevas formacionesBiografíaActividad académica e intelectualProfesor

Una biografía de Palmireno [Reseña]

1984

Libro sobre Juan Lorenzo Palmireno

The Multivariate Individual Selection of Diagnostic Tests and the Reserved Diagnostic Statement: An Optimum Combination of Two New Methods for the Co…

1984

A combination of two new methods for the diagnostic procedure in computer-aided differential diagnosis is presented. It is constructed on the basis of new results of our own in the field of mathematical decision theory and is demonstrated by the differential diagnosis of congenital heart diseases by means of ECG features.

Statement (computer science)Multivariate statisticsbusiness.industryComputer scienceDecision theoryDiagnostic testMachine learningcomputer.software_genreReliability engineeringComputer-aidedArtificial intelligenceDifferential diagnosisbusinesscomputerSelection (genetic algorithm)

13C NMR of carbonyl compounds. 3. Structure and dynamics of protonated enones and dienones

1984

Abstract The unsaturated ketones 1 1 – 10 10 were protonated at low temperatures and studied by dynamic 13C NMR spectroscopy. Four interconverting stereoisomers were detected which differ in their conformation with respect to the CO and CC (enone) single bond.

StereochemistryOrganic ChemistryProtonationNuclear magnetic resonance spectroscopyCarbon-13 NMRBiochemistrychemistry.chemical_compound13c nmr spectroscopychemistryComputational chemistryNMR spectroscopy of stereoisomersDrug DiscoverySingle bondEnoneTetrahedron Letters

A study of the diels-alder reaction of 3-oxabicyclo[3.3.0]oct-1(5)-ene-2,4-dione with cyclopentadiene and some related dienes

1984

Abstract The reaction of 3-oxabicyclo[3.3.0]oct-l(5)ene-2,4-dione, 2, with cyclopentadiene, 3, 5,5-diethoxycyclopentadiene, 4, and 6,6-dimethylfulvene, 5, is studied. Reaction of 2 and 3 yields the expected endo-adduct, while reaction of 2 and 5 gives a mixture of the endo- and exo-adducts whose ratio is slightly dependent on the reaction conditions. Attractive electrostatic interactions in the transition state leading to the exo-adduct can explain the absence of endo stereoselectivity in the last reaction. Steric factors seem to be responsible for the absence of reaction between 2 and 4. The analysis of the 13C NMR spectra of these adducts and some derived compounds confirms the tentative …

Steric effectsOrder of reactionCyclopentadieneBicyclic moleculeStereochemistryOrganic ChemistryBiochemistryMedicinal chemistryElimination reactionchemistry.chemical_compoundchemistryDrug DiscoveryStereoselectivityEne reactionDiels–Alder reactionTetrahedron