showing 36 of ~574560 from 574555 documents

A semi-classical derivation of the spin-orbit electromagnetic interaction

1973

PhysicsElectromagnetic interactionClassical mechanicsNuclear shell modelGeneral Physics and AstronomyNuclear forceNuclear drip lineAtomic physicsOrbit (control theory)Two-body problemSpin-½Lettere Al Nuovo Cimento Series 2

GAS CHROMATOGRAPHIC ESTIMATION OF ACETYLCHOLINE IN THE RABBIT HEART USING A NITROGEN SELECTIVE DETECTOR

1973

The distribution of ACh in the rabbit heart was investigated by a modified gas chromatographic estimation method. ACh was extracted with perchloric acid, precipitated as reineckate and demethylated with sodium benzenethiolate. The tertiary amines derived from ACh and other choline esters were concentrated by a microdistillation procedure. Gas chromatography was performed using a nitrogen selective detector. In the range of concentrations between 0.4 and 2.5 nmol ACh per tissue sample the coefficient of variation was 5.2 per cent. The recovery of ACh added to heart extracts was 101 per cent. Evidence for the identity of the choline ester isolated from rabbit hearts and authentic ACh was obta…

MaleChromatography GasHeart VentriclesCoefficient of variationSodiumchemistry.chemical_elementBlood PressureBiochemistryCholineCellular and Molecular Neurosciencechemistry.chemical_compoundMethodsmedicineAnimalsBioassayCholineHeart AtriaPerchloric acidButyrylcholineChromatographyChemistryMyocardiumAcetylcholineRatsButyratesBiological AssayFemaleRabbitsGas chromatographyPropionatesAcetylcholinemedicine.drugJournal of Neurochemistry

Further studies on associations between leprosy and genetic markers in human serum.

1973

Seven serum proteins were typed on a sample of 910 individuals from Angola, Africa. The sample consisted of both leprosy patients and healthy controls from the same geographical area. Significant associations with leprosy were found for the Hp and Pi systems. The results are discussed.

Black PeopleBiologyLeprosyGeneticsmedicineHumansGenetics (clinical)AllelesGeneticsPolymorphism GeneticHaptoglobinsTransferrinCeruloplasminBlood Proteinsmedicine.diseaseMolecular medicineBlood proteinsHuman geneticsGenetics PopulationPhenotypeAngolaGenetic markerImmunologyLeprosygamma-GlobulinsPeptide HydrolasesHumangenetik

Genetic variation in neuromuscular performance.

1973

Using a simple cumulative model of heredity plus environment, based on intrapair differences observed in monozygous (MZ) and dizygous (DZ) twins, the relative contribution of heredity to the interindividual variance in several neuromuscular parameters was determined with 15 pairs of male (8 MZ and 7 DZ) and 14 pairs of female (7 MZ and 7 DZ) twins ranging in age from 10 to 14 years. The data disclosed that in boys the variability in maximal mechanical (anaerobic) power was 99.2% genetically determined under the environmental conditions of the study. The corresponding heritability estimate values for the patellar reflex time and reaction time were 97.5% and 85.7%, respectively. In girls the …

MaleReflex StretchAdolescentPhysiologyPhysical ExertionNeuromuscular JunctionTwinsPhysiologyBiologymedicine.disease_causePregnancyPhysiology (medical)Genetic variationHereditymedicineReaction TimeHumansOrthopedics and Sports MedicineGenetic variabilityChildGeneticsmedicine.diagnostic_testBody WeightPublic Health Environmental and Occupational HealthPatellar reflexGeneral MedicineHuman physiologyPatellaHeritabilityBody HeightGenetic TechniquesGenetic CodeFemaleInternationale Zeitschrift fur angewandte Physiologie, einschliesslich Arbeitsphysiologie

An operon for histidine biosynthesis in Streptomyces coelicolor

1973

On the assumption that a cluster of five his genes (eight cistrons) in S. coelicolor corresponds to an operon, a genetic analysis of a constitutive mutant was carried out. This strain has a multi-site mutation localized at the (conventional) right end of the his cluster and is derepressed for at least two enzymes coded by genes of the cluster. The study of suitable heterozygous clones (heteroclones), showed the mutation to be cis-dominant, suggesting that the operator region is affected. Most likely the strain has a deletion connecting the his operon to an adjacent amm (ammonium requirement) operon as demonstrated by its inability to utilize nitrate as nitrogen source and to complement or r…

Genetics MicrobialHeterozygoteOperator (biology)Genetic LinkageOperonBiologyGenetic analysisOperonGeneticsHistidineAminesMolecular BiologyGeneAllelesCrosses GeneticGenes Dominantchemistry.chemical_classificationGeneticsNitratesStrain (chemistry)Streptomyces coelicolorChromosome MappingDrug Resistance Microbialbiology.organism_classificationStreptomycesQuaternary Ammonium CompoundsButyratesEnzymechemistryMutation (genetic algorithm)Molecular and General Genetics MGG

A Sensitive Method for Identification of DNA Dependent DNA Polymerases in Acrylamide Gels after Seperation by Micro Disc Electrophoresis

1973

Abstract DNA polymerase, disc electrophoresis, template affinity Two sensitive methods are described for detection of DNA dependent DNA polymerase activities in polyacrylamide gels after their fractionation by micro-disc electrophoresis. One technique is based on the increase in fluorescence of the ethidium bromide complex with template polydeoxyribonucleotides brought about by the action of the polymerases. The sensitivity of the previously described technique has been enhanced. Another method, 14 fold as sensitive, uses radioactive precursors in the enzyme assay after electrophoretic separation; washing, slicing and counting allows to evaluate incorporation into acid insoluble polymer, re…

DNA BacterialAcrylamidesbiologyDNA polymeraseElectrophoresis DiscTritiummedicine.disease_causeFluorescenceGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundBiochemistrychemistryDisc electrophoresisEthidiumAcrylamideDNA NucleotidyltransferasesEscherichia coliMethodsbiology.proteinmedicineGelsEscherichia coliDNA-directed DNA polymeraseDensitometryDNA NucleotidyltransferasesZeitschrift für Naturforschung C

false

1973

In the present paper the connection between an arbitrary polydisperse property and the molecular weight distribution is investigated using exact mathematical methods. On the basis of the superposition principle a general equation is derived which can be applied e.g. to the polydispersity problems connected with the Gel Permeation Chromatography, to the light scattering from dilute solutions of high polymers, or the ultracentrifuge. From this point of view, each of these phenomena is described by help of a linear operator with a special kernel, the analytical or numerical inversion of the operator yielding the molecular weight distribution of the system by help of an uniform algorithm. In de…

ChemistryGeneral equationOperator (physics)Polymer chemistryMathematical propertiesDie Makromolekulare Chemie

Low Energy Behaviour of the Phase Shifts for Velocity-Dependent Potentials

1973

PhysicsScattering amplitudeElastic scatteringLow energyPhysics and Astronomy (miscellaneous)Phonon scatteringPhase (waves)Scattering lengthInelastic scatteringAtomic physicsProgress of Theoretical Physics

Harvey's doctrine of the circulation of the blood in seventeenth-century Spain.

1973

HistoryPhilosophymedia_common.quotation_subjectCardiologyDoctrineAncient historyHistory 17th CenturySpainLawBlood CirculationHumansCirculation (currency)Geriatrics and Gerontologymedia_commonJournal of the history of medicine and allied sciences

Operationszwischenfall und Narkose

1973

Zur Klarung der Kausalitat bei einem todlichen Narkosezwischenfall mus der Gutachter die pharmakologischen Eigenschaften des verwendeten Anaestheticums, seine Dosierung und Applikationsweise in die Begutachtung mit einbeziehen. Die Narkosemittel sind von sehr unterschiedlicher chemischer Struktur, eine allgemein anerkannte Theorie uber ihre Wirkungsweise existiert nicht. Man bleibt deshalb auf Konzentrationsbestimmungen unter Beobachtung klinischer Effekte angewiesen. Konzentrationsablaufe bei Inhalationsnarkosen mit dem lipoidloslichen Narkosegas Halothan wurden wahrend und nach klinischen Routinenarkosen im Blut und in Tierversuchen in Blut und Geweben beobachtet. Es lassen sich drei Losu…

Gynecologymedicine.medical_specialtybusiness.industryMedicineAnatomybusinessPathology and Forensic MedicineZeitschrift für Rechtsmedizin

L'éducation comme investissement : la fin des illusions ?

1973

International audience

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationInvestissement éducatifComputingMilieux_MISCELLANEOUS

Die maximale lokale Erkl�rung einer ges�ttigten Formation

1973

General MathematicsHumanitiesMathematicsMathematische Zeitschrift

Effect of three-body cluster on the healing properties of the Jastrow Correlation function

1973

A variational equation for the Jastrow Correlation function is derived from the energy functional expanded up to three-body cluster terms. The asymptotic behaviour of this nonlinear equation is studied. The solutions show a healing at least of the type cos(tαr)/r2. The influence of higher cluster contributions is studied. Finally, it is discussed, how one can reduce the many-body cluster contributions to healing conditions to be used in the two-body cluster treatment.

PhysicsNuclear and High Energy PhysicsNonlinear systemCorrelation functionVariational equationQuantum electrodynamicsCluster (physics)Boundary value problemStatistical physicsEnergy functionalZeitschrift für Physik A Hadrons and nuclei

The effects of cold and glucagon on lipolysis, glycogenolysis and oxygen consumption in young chicks.

1973

Abstract 1. 1. To study the possible role of glucagon in avian thermoregulation the effects of cold exposure and glucagon on lipolysis, glycogenolysis and oxygen consumption were measured in young chicks. 2. 2. Cold exposure (+10°C) and glucagon injection (0·3 mg/kg, i.p. at +30°C) both caused a marked increase in the plasma FFA and a decrease in the liver glycogen content. 3. 3. It is suggested that glucagon possibly acts in the avian thermoregulation by producing at least lipolysis and glycogenolysis during cold exposure.

Blood Glucoseendocrine systemmedicine.medical_specialtyGlycogenolysisCold exposurechemistry.chemical_elementBiologyFatty Acids NonesterifiedGlucagonOxygenchemistry.chemical_compoundOxygen ConsumptionInternal medicinemedicineLipolysisAnimalsGlycogenGeneral MedicineThermoregulationGlucagonStimulation ChemicalLiver GlycogenCold TemperatureEndocrinologychemistryLiverDepression ChemicalGlucagon InjectionChickenshormones hormone substitutes and hormone antagonistsBody Temperature RegulationComparative biochemistry and physiology. A, Comparative physiology

En guise d'introduction

1973

International audience

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationEcononie de l'éducationComputingMilieux_MISCELLANEOUS

Fl�chen Beschr�nkter Mittlerer Kr�mmung in Einer Dreidimensionalen Riemannschen Mannigfaltigkeit

1973

In recent papers HILDEBRANDT [11] and HARTH [5] proved the existence of solutions of the problem of Plateau for surfaces of bounded mean curvature with fixed and free boundaries in E3 and for minimal surfaces with free boundaries in a Riemannian manifold, respectively. Here their methods will be combined to solve the problem of Plateau for surfaces of bounded mean curvature in a Riemannian manifold. This will be done for fixed and free boundaries. Moreover, isoperimetric inequalities for the solutions will be given.

Mean curvature flowMean curvatureMinimal surfaceGeneral MathematicsPrescribed scalar curvature problemMathematical analysisMathematics::Differential GeometryIsoperimetric dimensionRiemannian manifoldRicci curvatureMathematicsScalar curvatureManuscripta Mathematica

Repair of the mandibular nerve by means of autologous nerve grafting after resection of the lower jaw

1973

Summary On the basis of two cases we demonstrate our method of autologous nerve grafting for substitution of the mandibular nerve after mandibular resection. The sural nerve served as a donor nerve, the graft was imbedded microsurgically at the juncture points by means of a perineurial interfascicular nerve suture. Oversized grafts of about 20 cm in length were chosen intentionally in order to insert them without tension between the stumps of the recipient nerve and outside the regeneration zone of the bone. In both cases complete resensibilization of the lower lip was reached after about six months.

AdultMicrosurgerymedicine.medical_specialtyMandibular NerveMandibular nerveLower lipSural nerveTransplantation AutologousResectionAmeloblastomaPostoperative ComplicationsSural Nervestomatognathic systemmedicineHumansParesthesiaChildNerve graftingbusiness.industryGeneral MedicineAnatomyDenervationMandibular resectionLipNerve RegenerationOsteotomySurgeryMandibular Neoplasmssurgical procedures operativeFemaleSurgeryEpineurial repairNerve suturebusinessJournal of Maxillofacial Surgery

Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C&42horbar; sites

1973

Sensitized cells (EA) bearing different numbers of &42horbar; sites were tested for their ability to generate chemotactic activity from C-EDTA. From the results it can be shown that: 1 the amount of chemotactic activity generated parallels the number of &42horbar; sites bound to the cell surface, 2 all &42horbar; sites clustered around a single hemolytic site are enzymatically active as far as generation of chemotactic activity is concerned, and, 3 no difference can be demonstrated with IgG or IgM antibodies

Binding SitesIgm antibodyChemotaxisImmunologyCellChemotaxisAntigen-Antibody ComplexComplement System ProteinsBiologyCytotoxicity Tests ImmunologicMolecular biologyRatsImmune systemmedicine.anatomical_structureImmunologyLeukocytesmedicineAnimalsImmunology and AllergyRabbitsEdetic AcidEuropean Journal of Immunology

On the formation of maars

1973

The Pleistocene maars in the Eifel region of Germany, and Massif Central in France, formed when fissures opened at the bottom of older valleys allowing stream water to pour down them and come into contact with rising magma. The resulting phreato-magmatic eruptions gave rise to both base surge and air-fall deposits. Spalling of wall rock at depth enlarged the fissure into an eruption chamber. Subsidence along a ring fault into the eruption chamber accounts for the larger crater cut into the country rocks. The volume relationship between the crater excavated, the ejected pyroclastic debris of the rim and the volume below the floor of the crater, indicates that the volume of the maar ejecta is…

geographygeography.geographical_feature_categoryPyroclastic rockDebrisMaarDiatremeImpact craterGeochemistry and PetrologyMagmaPetrologyEjectaGeomorphologyGeologyWall rockBulletin Volcanologique

Hypersurfaces of prescribed mean curvature over obstacles

1973

Let ~2 be a bounded domain in the euclidean space IR", n-> 2, with Lipschitz boundary ~ . We shall consider surfaces which are graphs of functions u defined on f2 having prescribed mean curvature H=H(x, u) with the side condition that they should be bounded from below by an obstacle ~b. The case H = 0 (minimal surfaces) has been discussed in detail by several authors, compare [6, 7, 12, 13, 17, 18, 20, 21, 24] of the references. Tomi [-31] has also investigated parametric surfaces with variable H. More general variational problems with obstructions have been discussed in [-9] and [-10]. During the session on "Variationsrechnung", held from June 18th to June 24th, 1972 in Oberwolfach, Mirand…

Pure mathematicsMean curvature flowMinimal surfaceMean curvatureEuclidean spaceGeneral MathematicsBounded functionBoundary (topology)Lipschitz continuityDomain (mathematical analysis)MathematicsMathematische Zeitschrift

Unterkieferwachstumsstörungen bei juveniler Polyarthritis

1973

Der Beitrag enthalt Hinweise fur Wachstumsstorungen des Unterkiefers als Folge polyarthritischer Erkankungen. Es werden 2 Patienten vorgestellt, bei denen in der Jugend Gelenkbeschwerden aufgetreten waren und spater Veranderungen des Profils beobachtet worden sind. Der rotgenkephalometrische Befund zeigt eine eigenartige Verformung der Mandibula, die mit der fortschreitenden Zerstorung des Processus articularis das Ausere der Patienten nachteilig verandert.

Gynecologymedicine.medical_specialtybusiness.industryMedicineOrthodonticsGeneral MedicineOral SurgerybusinessFortschritte der Kieferorthopädie

Testing of a constitutive equation for entangled networks by elongational and shear data of polymer melts

1973

An entangled network such as a polymer melt or a concentrated solution is here described by a set of two simultaneous equations. One of them is a balance of entanglements, the other gives the stress in the classical form of aMaxwell equation.

chemistry.chemical_classificationMaterials scienceShear viscosityConstitutive equationQuantum PhysicsMechanicsPolymerCondensed Matter PhysicsStress levelCondensed Matter::Soft Condensed MatterShear (geology)chemistrySimultaneous equationsPolymer chemistryGeneral Materials SciencePolymer meltRheologica Acta

Atemmechanismus und Kreislauf des Amazonasfisches Pirarucu

1973

General MedicineBiologyEcology Evolution Behavior and SystematicsDie Naturwissenschaften

Small-angle x-ray scattering experiments for investigating the validity of the two-phase model

1973

A New method for evaluating SAXS curves of polymer samples with lamellar structure is applied to two typical scattering curves measured with a solution-crystallized linear polyethylene and a melt-crystallized branched polyethylene respectively. The method permits a rigorous check of the validity of the two-phase model and yields, without additional measurement, the volume fractions of the two phases and the difference in their densities. The densities can than be obtained by measuring the overall density of the sample. The results are: ρc = 0.996 g/cm3,ρa = 0.854 g/cm3, wa = 0.20 for the solution-crystallized sample; ρc = 0.967 g/cm3,ρa = 0.850 g/cm3, wa = 0.36 for the melt-crystallized sam…

Linear low-density polyethylenechemistry.chemical_classificationchemistry.chemical_compoundMaterials scienceVolume (thermodynamics)chemistryScatteringSmall-angle X-ray scatteringAnalytical chemistryPhase modelLamellar structurePolymerPolyethyleneJournal of Polymer Science Part A-2: Polymer Physics

The affinity for oxygen of polyphenoloxidase in grapes

1973

The influence of oxygen on the reaction of polyphenoloxidase in grapes was determined. Using crude extracts of grapes with a sufficiently high polyphenoloxidase activity on a substrate of pyrocatechol, apparentKm values for oxygen, at 25° C were calculated as 1.1 × 10−4mol (or 9% 02) for Sultana, and 1 × 10−4mol (or 8% O2) for Doradillo grapes. The importance of these figures for wine making is discussed.

WineChromatographyChemistrySubstrate (chemistry)chemistry.chemical_elementGeneral ChemistryFood scienceBiochemistryOxygenIndustrial and Manufacturing EngineeringFood ScienceBiotechnologyZeitschrift für Lebensmittel-Untersuchung und -Forschung

Pour une analyse économique de la formation permanente

1973

International audience

Formation permanente[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationAnalyse économiqueComputingMilieux_MISCELLANEOUS

Les disparités régionales en matière de taux de scolarisation

1973

International audience

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationFranceDisparité régionaleComputingMilieux_MISCELLANEOUSTaux de scolarisation

Growth of polyoxymethylene crystals during cationic polymerization of trioxane in nitrobenzene

1973

Nitrobenzenechemistry.chemical_compoundTrioxanePolyoxymethyleneChemistryPolymer chemistryGeneral EngineeringCationic polymerizationGeneral Materials SciencePhotochemistryJournal of Polymer Science: Polymer Letters Edition

Analyse théorique de la demande d'éducation et optimisation de l'investissement éducatif

1973

International audience; Cet article cherche à expliquer la pluralité des comportements individuels en matière d'éducation. Celle-ci est traitée en tant qu'investissement ainsi que dans la théorie du capital humain. Cependant, la valeur de l'investissement n'est pas mesurée de la même façon suivant les caractéristiques socio-économiques du décideur en raison d'une part des imperfections dans le marché du capital et d'autre part, de l'incertitude sur les flux de coûts et des revenus associés au capital humain. En outre, des indicateurs d'efficacité de la planification sont suggérés.

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationInvestissement éducatifDemande d'éducationOptimisationAnalyse théoriqueInvestissement en capital humain

Table ronde IREDU 24-25 mai 1973 : compte rendu des débats

1973

International audience

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Educationéconomie de l'éducationComputingMilieux_MISCELLANEOUS

Distribution of chlorpromazine in a simplified blood influenced by various drugs

1973

The binding of chlorpromazine to erythrocytes and to albumin as influenced by other drugs was studied in a simplified blood (31.5±0.3% bovine erythrocytes, 4 g-% bovine serum albumin in 0.02 M phosphate buffer solution containing 0.15 M NaCl). the total concentration of chlorpromazine in the simplified blood was 10−4 M, the concentration of the displacing drugs was 10−3 M. After an incubation period of 3 h at 22° C the chlorpromazine concentration was determined in the albumin solution after centrifugation of the blood at 3000×g and in the aqueous phase after ultracentrifugation at 150000×g. Under control conditions 68.1±0.9% of chlorpromazine was bound to the erythrocytes, 28.5±0.9% was bo…

ErythrocytesChlorpromazineIndomethacinSuraminBenzoatesBinding CompetitiveIncubation periodCoumarinsmedicineAnimalsDistribution (pharmacology)CentrifugationThiopentalBovine serum albuminChlorpromazinePharmacologySulfonamidesBinding SitesChromatographyQuininebiologyProbenecidChemistryFatty AcidsAqueous two-phase systemAlbuminSerum Albumin BovineGeneral MedicineChlorothiazideTetracyclineAntidepressive AgentsSalicylatesAcetazolamidePhenylbutazoneSolubilityPhenytoinbiology.proteinCattleUltracentrifugeDeoxycholic AcidProtein Bindingmedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology

Untersuchungen von Polymeren im Massenspektrometer. I. Fragmentierungsreaktionen von oligomeren β-Alaninen

1973

Beim Abbau von Poly-β-alaninen entstehen unter milden Pyrolysebedingungen oligomere Carbonsaureamide. Die Fragmentierungsreaktionen derartiger Pyrolysebruchstucke werden an dimeren bis tetrameren β-Lactamen untersucht. Als Hauptfragmentierungsreaktionen werden nach Ionisation an einem der Heteroatome αN-, Keten-, αO-, und βO-Spaltung mit MCLAFFERTY-Umlagerung gefunden. The degradation of poly-β-alanines under mild pyrolytical conditions yields oligomeric amids. Dimeric, trimeric and tetrameric β-lactames were used to study the fragmentation reactions of those degradation products. After ionisation at one of the hetero atoms αN-, keten-, αO- and βO-cleavage (with MCLAFFERTY-rearrangement) we…

Fragmentation (mass spectrometry)ChemistryGeneral Materials ScienceMedicinal chemistryAngewandte Makromolekulare Chemie

Untersuchungen von Polymeren im Massenspektrometer. II. Abbaureaktionen von Poly-β-alaninen

1973

Die Abbaureaktionen von Poly-β-alaninen bei der direkten Pyrolyse im Massenspektrometer wurden untersucht. Die thermischen Abbaureaktionen und die Fragmentierung in der Ionenquelle waren unterscheidbar. Die pyrolytische Spaltung verlauft unter den angewendeten Bedingungen fast ausschlieslich zwischen Amidstickstoff und β-Kohlenstoff und fuhrt unter Disproportionierung zu oligomeren β-Alaninen. Die entstehenden Pyrolysebruchstucke werden nach uberwiegender Ionisation an den Heteroatomen unter αN-, αO-, βO- und Keten-Spaltung fragmentiert. The degradation reactions of poly-β-alanines by direct pyrolysis in the mass spectrometer was investigated. The thermal degradation step and the fragmentat…

ChemistryPolymer chemistryGeneral Materials ScienceAngewandte Makromolekulare Chemie

Polymerisation von Trioxan zu kristallinem POM im Gleichgewicht

1973

General MedicineAngewandte Chemie

Die bestimmung des trägheitsradius von polymethylmethacrylat im glaszustand durch neutronenbeugung

1973

Materials sciencePolymer chemistryGeneral MedicineDie Makromolekulare Chemie

Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs

1973

A number of laboratory tests can be employed to examine the sensitivity of human bladder tumour cells to various chemotherapeutic agents.-Their principles and methods, and some preliminary results, are described with special reference to certain in vitro and in vivo cytotoxicity tests and to heterotransplantation in the hamster. Satisfactory agreement has sometimes been observed between experimental results and clinical responses, but our experience is still very limited.-The employment of several such tests would probably lead to a greater degree of reliability in the laboratory assessment of the sensitivity of bladder tumours to cytotoxic drugs.

Oncologymedicine.medical_specialtyPathologyAdministration TopicalUrologyTransplantation HeterologousHuman bladderDrug ResistanceHamsterAntineoplastic AgentsBLADDER PAPILLOMAThiophenesFluorescenceCricetinaeInternal medicinemedicineAnimalsHumansGlycosidesMelphalanIn vivo cytotoxicityPodophyllotoxinCell NucleusCarcinoma Transitional Cellbusiness.industryDaunorubicinDemecolcineDNA NeoplasmCytotoxicity Tests ImmunologicMicroscopy FluorescenceUrinary Bladder NeoplasmsDoxorubicinProtein BiosynthesisAntineoplastic DrugsOxidoreductasesbusinessNeoplasm TransplantationThiotepaUrological Research