showing 36 of ~574560 from 574555 documents
Rischio di liquidità, profili di governance e forme istituzionali: evidenze empiriche su un campione di banche europee
2022
La crisi finanziaria 2007-2009 e l’emergenza pandemica da Covid-19 hanno evidenziato l’importanza del mantenimento di condizioni di liquidità per il regolare funzionamento delle imprese, del sistema finanziario e dei mercati. Questo lavoro ha l’obiettivo di analizzare le relazioni esistenti tra le caratteristiche della governance bancaria, con particolare riferimento alla composizione del board e del risk committee e l’esposizione al rischio di liquidità della banca, declinato quale disallineamento delle scadenze tra prestiti e depositi. L’indagine è condotta su un campione di banche europee e mette in evidenza come l’azione del risk committee nella mitigazione del rischio di liquidità sia …
The Sehgal’s Fixed Point Result in the Framework of ρ-Space
2022
In this paper, we prove a fixed point theorem of Sehgal type (see Sehgal, V.M., Proc Amer Math Soc 23: 631–634, 1969) in a more general setting of ρ-space (see Secelean, N.A. and Wardowski, D., Results Math, 72: 919–935, 2017). In this way, we can find, as particular cases, some results of Sehgal type in metric, b-metric and rectangular b-metric spaces.
Predominio de las cheapfakes en redes sociales. Complejidad técnica y funciones textuales de la desinformación desmentida en Argentina durante 2020
2022
Research on disinformation concentrates a growing interest in the design of deepfakes and the possible political, economic and social implications of their viral dissemination on social networks. However, as much or more worrying are the cheapfakes: the hoaxes created by the users themselves through the native features of their mobile devices, the rude manipulation of pre-existing files or the simple addition of text that alters the original meaning of the shared messages. The objective of this research is to analyze the degree of technological complexity of the disinformation that circulated in Argentina during 2020 throughout social networks, as well as the role that the text played in it…
Effect of a Craniosacral Therapy Protocol in People with Migraine: A Randomized Controlled Trial
2022
Background: Migraine is a common neurological disorder, and it is the second leading cause of disability worldwide. Manual techniques based on physical therapy have been proposed to improve migraine aspects; however, further research is needed on their effectiveness. The aim of this study was to evaluate the effectiveness of a craniosacral therapy protocol on different features in migraine patients. Methods: Fifty individuals with migraine were randomly divided into two groups (n = 25 per group): (i) craniosacral therapy group (CTG), following a craniosacral therapy protocol, and (ii) sham control group (SCG), with a sham treatment. The analyzed variables were pain, migraine severity and fr…
An adaptation-mitigation game: does adaptation promote participation in international environmental agreements?
2022
AbstractThis paper studies how the investment in adaptation can influence the participation in an international environmental agreement (IEA) when countries decide in adaptation before they choose emissions. Three types of agreements are studied, a mitigation agreement for which countries coordinate their decisions only on emissions; an adaptation agreement for which there is only coordination when countries decide their levels of adaptation and a complete agreement when there is coordination in both emissions and adaptation levels. In every case, we assume that the degree of effectiveness of adaptation is bounded from above, in order words, adaptation can alleviate the environmental proble…
L'ouverture d'une voie de recours, condition de l'émission d'une décision d'enquête européenne
2022
International audience
Towards a local mass mortality of the Mediterranean orange coral Astroides calycularis (Pallas, 1766) in the Pelagie Islands Marine Protected Area (I…
2022
In late summer 2020, a widespread mortality event severely affected colonies of the Mediterranean endemic orange coral Astroides calycularis in the Pelagie Islands (Strait of Sicily, southern Mediterranean Sea). The degree of the mortality impact at seven study sites of the archipelago (five within the Pelagie Islands Marine Protected Area) was quantified by estimating the proportion of affected colonies in populations of A. calycularis. Five of the seven surveyed sites revealed a low degree of impact, but Punta Ruperta and Cala Creta (both on the island of Lampedusa) showed a medium impact with values of 32.3% and 30.5% of affected colonies respectively. The 2020 mortality event coincided …
Techniques, Tricks, and Stratagems of Oral Cavity Computed Tomography and Magnetic Resonance Imaging
2022
The oral cavity constitutes a complex anatomical area that can be affected by many developmental, inflammatory, and tumoural diseases. MultiSlice Computed Tomography (MSCT) and Magnetic Resonance Imaging (MRI) currently represent the essential and complementary imaging techniques for detecting oral cavity abnormalities. Advanced MRI with diffusion-weighted imaging (DWI) and dynamic contrast-enhanced perfusion-weighted imaging (DCE-PWI) has recently increased the ability to characterise oral lesions and distinguish disease recurrences from post therapy changes. The analysis of the oral cavity area via imaging techniques is also complicated both by mutual close appositions of different mucosa…
Association of body mass index with COVID-19 related in-hospital death.
2022
Background: Patients with extreme body mass indices (BMI) could have an increased risk of death while hospitalized for COVID-19. Methods: The database of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) was used to assess the time to in-hospital death with competing-risks regression by sex and between the categories of BMI. Results: Data from 12,137 patients (age 60.0 ± 16.2 years, 59% males, BMI 29.4 ± 6.9 kg/m2 ) of 48 countries were available. By univariate analysis, underweight patients had a higher risk of mortality than the other patients (sub-hazard ratio (SHR) 1.75 [1.44e2.14]). Mortality was lower in normal (SHR 0.69 [0.58e0.85]), overweight (SH…
Facilitating innovation in FinTech: a review and research agenda
2022
AbstractThe purpose of this paper is to carry out content analyses on the existing literature to investigate the knowledge state of innovation facilitators adopted to promote financial innovation. In total, 56 papers were analysed using the NVivo software package. Three categories of innovation facilitators emerged from the literature capturing the perspective of regulators, incumbents and new entrants. Each identified instrument is defined and its processes and implications described. Many initiatives were led by regulators, revealing a regulatory strategy change from risk-based to opportunity-based regulation, with regulatory sandboxes being the most commonly adopted instrument. Incumbent…
Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents
2022
Over the last decade, several compounds have been identified for the treatment of obesity. However, due to the complexity of the disease, many pharmacological interventions have raised concerns about their efficacy and safety. Therefore, it is important to discover new factors involved in the induction/progression of obesity. Adipose stromal/stem cells (ASCs), which are mostly isolated from subcutaneous adipose tissue, are the primary cells contributing to the expansion of fat mass. Like other cells, ASCs release nanoparticles known as extracellular vesicles (EVs), which are being actively studied for their potential applications in a variety of diseases. Here, we focused on the importance …
CO2 and CH2 Adsorption on Copper-Decorated Graphene: Predictions from First Principle Calculations
2022
Calculations were performed using Latvian Super Cluster (LASC), located in Center of Excellence at Institute of Solid State Physics, the University of Latvia, which is supported by European Union Horizon2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under Grant Agreement No. 739508, project CAMART2. The authors would like to express their gratitude for funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 768789 (CO2EXIDE project). In the last stage of investigation and during the preparation of the publication, the authors were assisted by the postdoc D.B. with his own funding from project No. 1.1.1.2/VIAA/l/16/147 (…
Specific Zn(II)-binding site in the C-terminus of Aspf2, a zincophore from Aspergillus fumigatus
2022
Abstract Aspergillus fumigatus, one of the most widespread opportunistic human fungal pathogens, adapts to zinc limitation by secreting a 310 amino acid Aspf2 zincophore, able to specifically bind Zn(II) and deliver it to a transmembrane zinc transporter, ZrfC. In this work, we focus on the thermodynamics of Zn(II) complexes with unstructured regions of Aspf2; basing on a variety of spectrometric and potentiometric data, we show that the C-terminal part has the highest Zn(II)-binding affinity among the potential binding sites, and Ni(II) does not compete with Zn(II) binding to this region. The 14 amino acid Aspf2 C-terminus coordinates Zn(II) via two Cys thiolates and two His imidazoles and…
Tuoretta tutkimusta suomen oppimisesta ja oppijoista
2022
Youth Athletes' Perception of Existence and Prevalence of Aggression and Interpersonal Violence and Their Forms in Serbia.
2022
Aggression and interpersonal violence (IV) against children and youth are issues in contemporary society. The current study reports on the youth athletes’ perception of the aggression and IV prevalence and its manifestation forms in a Serbian context. The sample included athletes (N = 2091) between the age of 11 and 18 years. Data were collected through an ad-hoc questionnaire created by the authors. Respondents’ answers to introductory questions about the frequency of IV indicated its absence (78.1%). However, the answers to the questions about specific forms of violent peer behavior indicated forms as well as the time and place where IV most often occurs. They underlined that …
Läpileikkaus Suomen kielelliseen moninaisuuteen kielielämäkertojen kautta
2022
Suomalaisten kielellistä elämää. Sata suomalaista kielellistä elämäkertaa -hankkeen satoa. (2020). Toimittanut Kaarina Hippi, Hanna Lappalainen ja Pirkko Nuolijärvi. Helsinki: SKS. 387 s. ISBN 978-951-858-247-5
The Company Clusters Power in Tourism Destinations: The Network Configuration and the Business Organisation
2022
Better and greater coordination and integration between companies are essential for tourist destination development processes improving competitiveness. Moreover, it is difficult to imagine that all companies can cooperate. In this way, we can imagine finding a group of companies that, for several reasons, decide to cooperate, creating some clusters as small groups. Companies with stable connections with other clusters or relevant companies could be relevant and central to Tourism Destination (TD) management. In this way, the knowledge of network articulation seems to be critical for TD management business dynamics. In most cases, the relationships are hidden and not formalised, increasing …
Evolution of the magma system of Pantelleria (Italy) from 190 ka to present
2022
The eruptive history of Pantelleria has been marked by the eruption of nine peralkaline ignimbrites, with inter-ignimbrite episodes from small, local volcanic centres. New whole-rock geochemical data are presented for seven ignimbrites and used with published data for younger units to track compositional changes with time. From»190 ka, silicicmagmatismwas dominated by comenditic trachyte to comendite compositions, evolving along generally similar liquid lines of descent (LLOD). The final ignimbrite, the Green Tuff (»46 ka), was tapped from a compositionally zoned pantelleritic upper reservoir to a trachytic mush zone. Younger (20–7 ka) silicic magmatism has been relatively small scale, with…
Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil.
2022
Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, consequently, worse prognosis. The aim of this study was to evaluate the relationship between race/skin color and OPC prognosis in Brazil. This is a cross-sectional epidemiological study using OPC data from the National Cancer Institute between the years 2000 and 2019. The selected variables were: gender, race/skin color, age, education, smoking and alcohol consumption, stage of the disease and disease status at …
Diversity in CLIL as experienced by Finnish CLIL teachers and students : matters of equality and equity
2022
This article focuses on how Finnish CLIL teachers and students orient to and experience diversity in CLIL. The data consist of teacher and student interviews that were analysed using qualitative content analysis to identify recurrent themes with regard to diversity. The findings indicate that the theme of equality in the sense of ‘the same for all’ in both teaching, assessing and homework was readily brought up by both groups, reflecting the ethos of equality prevalent in Finnish education. Equity, however, was not similarly highlighted even though it is a guiding principle alongside equality in the Finnish Core Curriculum for Basic Education. Teachers were found reluctant to topicalise div…
Dyslexia, Self-efficacy, and Language Instruction in Foreign Language Learning -- A Mixed Quantitive-qualitative Study
2022
The aim of the research is to investigate the interdependence between dyslexia, self-efficacy, and foreign language instruction. The author of the study applied a mixed-method: quantitative and qualitative. The quantitative data were collected through self-efficacy questionnaires filled out by dyslexic and non-dyslexic students, and the qualitative data were collected during a case study conducted with a dyslexic student. The research findings in the first quantitative part of the study reveal that self-efficacy in dyslexic students is substantially lower than in non-dyslexic students. According to the results of the second mixed, quantitative - qualitative part of the study encompassing a …
Bi3+doping in 1D ((CH3)3SO)PbI3: A model for defect interactions in halide perovskites
2022
The recently described monodimensional hybrid pseudo-perovskite ((CH3)3SO)PbI3 exhibits complete Pb2+/Bi3+ miscibility in the B site. Heterovalent substitution imposes that charge-compensating defects are introduced in the lattice as well. This paper reports the energetics of point defects and the interaction between charge-compensating defects that occur upon Bi3+ doping in ((CH3)3SO)PbI3. Periodic DFT simulations were employed to analyze the formation energy of Pb2+ vacancies, (CH3)3SO+ vacancies, iodide vacancies, or the insertion of interstitial iodide ions. Solid solutions with a large Bi3+ content were modeled considering different charge compensation defects (Pb2+ vacancies, (CH3)3SO…
Mathematical Methods for Research Excellence : Book of Abstracts
2022
Measurement of inclusive charged-particle b-jet production in pp and p-Pb collisions at √sNN = 5.02 TeV
2022
A measurement of the inclusive b-jet production cross section is presented in pp and p-Pb collisions at √sNN = 5.02 TeV, using data collected with the ALICE detector at the LHC. The jets were reconstructed in the central rapidity region |η| < 0.5 from charged particles using the anti-kT algorithm with resolution parameter R = 0.4. Identification of b jets exploits the long lifetime of b hadrons, using the properties of secondary vertices and impact parameter distributions. The pT-differential inclusive production cross section of b jets, as well as the corresponding inclusive b-jet fraction, are reported for pp and p-Pb collisions in the jet transverse momentum range 10 ≤ pT,ch jet≤ 100 GeV…
Apurahatutkijat yliopistojen rakenteissa
2022
Cross-linked natural IntegroPectin films from citrus biowaste with intrinsic antimicrobial activity
2022
AbstractPectin recovered via hydrodynamic cavitation (IntegroPectin) from lemon and grapefruit agri-food waste intrinsically containing antimicrobial bioactive substances (flavonoids, phenolic acids, terpenes, and terpenoids) was used to generate innovative and eco-compatible films that efficiently inhibit the growth of Gram-negative pathogens. Extensive characterization of films confirmed the presence of these substances, which differently interact with the polysaccharide polymer (pectin), plasticizer (glycerol), surfactant (Tween 60), and cross-linker (Ca2+), conferring to these films a unique structure. Besides, IntegroPectin-based films constitute versatile systems for the sustained, co…
Initiator-Directed Transcription: Fission Yeast Nmtl Initiator Directs Preinitiation Complex Formation and Transcriptional Initiation
2022
The initiator element is a core promoter element encompassing the transcription start site, which is found in yeast, Drosophila, and human promoters. This element is observed in TATA-less promoters. Several studies have defined transcription factor requirements and additional cofactors that are needed for transcription initiation of initiator-containing promoters. However, those studies have been performed with additional core promoters in addition to the initiator. In this work, we have defined the pathway of preinitiation complex formation on the fission yeast nmt1 gene promoter, which contains a functional initiator with striking similarity to the initiator of the human dihydrofolate red…
Mediterranean plant germination reports – 4
2022
This is the fourth issue of the series of germination reports from Mediterranean areas (sensu Med-Checklist). It comprises germination protocols for 17 taxa: Centaurea from central Italy by V. Di Cecco & L. Di Martino (No. 86); Limonium from Sardinia by M. E. Boi & al. (No. 87); Glaucium, Helichrysum, and Plantago from Central Italy by S. Magrini & al. (Nos. 88-90); Anthemis from Sicily by C. Blandino & al. (Nos. 91-97); Silene from Sicily and Calabria by C. Brullo & C. Salmeri (Nos. 98-102); lastly, Armeria from North Italy by Vuerich & al. (2022).
Immunity and Nutrition: The Right Balance in Inflammatory Bowel Disease
2022
Inflammatory bowel disease (IBD) is an increasingly urgent medical problem that strongly impairs quality of life for patients. A global rise in incidence has been observed over the last few decades, with the highest incidence rates recorded in North America and Europe. Still, an increased incidence has been reported in the last ten years in newly industrialized countries in Asia, including China and India, both with more than one billion inhabitants. These data underline that IBD is an urgent global health problem. In addition, it is estimated that between 20% and 30% of IBD patients will develop colorectal cancer (CRC) within their lifetime and CRC mortality is approximately 50% amongst IB…
Infrared nanospectroscopic mapping of DNA molecules on mica surface
2022
Significant efforts have been done in last two decades to develop nanoscale spectroscopy techniques owning to their great potential for single-molecule structural detection and in addition, to resolve open questions in heterogeneous biological systems, such as protein-DNA complexes. Applying AFM-IR technique has become a powerful leverage for obtaining simultaneous absorption spectra with a nanoscale spatial resolution for studied proteins, however the IR-AFM investigation of DNA molecules on surface, as a benchmark for a nucleoprotein complexes nanocharacterization, has remained elusive. Herein, we demonstrate methodological approach for acquisition of IR-AFM mapping modalities with corres…
A comparative analysis of two immersive virtual reality systems in the integration and visualization of natural hand interaction
2022
AbstractIt is generally accepted that the use of natural interaction provides a positive impact in Virtual Reality (VR) applications. Therefore, it is important to understand what is the best way to integrate and visualize this feature in VR. For this reason, this paper presents a comparative study of the integration of natural hand interaction in two immersive VR systems: a Cave Audio Visual Experience (CAVE) system –where users’ real hands are visible– and a non-see-through Head-Mounted Display (HMD) system –where only a virtual representation of the hands is possible–. In order to test the suitability of using this type of interaction in a CAVE and compare it to an HMD, we raise six rese…
Kriisinkestävä koulu
2022
Meitä edelleen kiusaavan pandemian alettua suomalainen yhteiskunta pysähtyi tai joutui muuttamaan käytäntöjään monella toiminta-alueella. Yksi koko yhteiskuntaa heijasteleva toiminta-alue oli koululaitos eri tasoillaan. Marja-Kristiina Lerkkanen tarkastelee artikkelissaan tuoreisiin tutkimustuloksiin perustuen opettajien työn ja työtilanteen muuttumista ja sen heijastumista niin oppilaisiin kuin koko koulun toimintaan. Esiin nousevat koulujen ja kotien resurssit selvitä muuttuneessa tilanteessa sekä täysin uudesta tilanteesta saatavat opit tulevaisuutta ajatellen. nonPeerReviewed
Volcanological evolution of Pantelleria Island (Strait of Sicily) peralkaline volcano: a review
2022
International audience; Pantelleria volcano has a particularly intriguing evolutionary history intimately related to the peralkaline composition of its explosively erupted magmas. Due to the stratigraphic complexity, studies over the last two decades have explored either only the pre-Green Tuff ignimbrite volcanism or the post-Green Tuff activity. We here focus on the whole evolutionary history, detailing the achievements since the first pioneering studies, in order to illustrate how the adoption and integration of progressively more accurate methods (40 Ar/ 39 Ar, paleomagnetism, petrography, and detailed field study) have provided many important independent answers to unresolved questions…
Measuring the Rate of Information Exchange in Point-Process Data With Application to Cardiovascular Variability
2022
The amount of information exchanged per unit of time between two dynamic processes is an important concept for the analysis of complex systems. Theoretical formulations and data-efficient estimators have been recently introduced for this quantity, known as the mutual information rate (MIR), allowing its continuous-time computation for event-based data sets measured as realizations of coupled point processes. This work presents the implementation of MIR for point process applications in Network Physiology and cardiovascular variability, which typically feature short and noisy experimental time series. We assess the bias of MIR estimated for uncoupled point processes in the frame of surrogate…
Transcriptomic profile of epileptic children treated with ketogenic therapies.
2022
Background: Ketogenic dietary therapies (KDT) are used as a treatment in childhood epilepsy. However, their mechanism has not yet been established. The main objective of this study was to determine the changes in the transcriptomic profile induced by KDT in children with epilepsy in order to shed light on its possible mechanisms. Methods: Eight children with refractory epilepsy were enrolled in the study. Peripheral blood mononuclear cells were obtained before and after the children were treated with KDT for a minimum of 6 months. RNA was extracted and mRNA and miRNA profiling were performed and analyzed. Results: Our intervention with KDT significantly reduced the seizure number in seven o…
Dual Inhibition of Myc Transcription and PI3K Activity Effectively Targets Colorectal Cancer Stem Cells
2022
Despite advances in the curative approach, the survival rate of advanced colorectal cancer (CRC) patients is still poor, which is likely due to the emergence of cancer cell clones resistant to the available therapeutic options. We have already shown that CD44v6-positive CRC stem cells (CR-CSCs) are refractory toward standard anti-tumor therapeutic agents due to the activation of the PI3K pathway together with high HER2 expression levels. Tumor microenvironmental cytokines confer resistance to CR-CSCs against HER2/PI3K targeting by enhancing activation of the MAPK pathway. Here, we show that the CSC compartment, spared by BRAF inhibitor-based targeted therapy, is associated with increased ex…