showing 36 of ~574560 from 574555 documents
Human genetic polymorphisms and risk of viral infection after solid organ transplantation.
2021
The immune system plays a key role in the host defense against viral pathogens. A signaling cascade is activated upon infection involving a variety of molecules such as pattern-recognition receptors (PRRs), interleukins or antiviral interferons. Long-term immunosuppression after solid organ transplantation (SOT) mainly abrogates adaptive T-cell-mediated responses, thus highlighting the relative contribution of innate immunity. Single-nucleotide polymorphisms (SNPs) within genes coding for PRRs or soluble mediators have been associated with differential susceptibility to viral infections among SOT recipients. A protective effect against cytomegalovirus (CMV) infection or disease has been att…
How to add a biodiversity survey to an already existing national pedologic survey? Case study of the french soil quality monitoring network
2021
International audience; Despite its importance for human activities, soil biodiversity remains largely unknown. This gap of knowledge is a strong limit for studies including it such as in the agricultural field. Particularly, in France, no large-scale monitoring of soil biodiversity exist for the moment except for microorganisms (bacteria and fungi). Aware to this need, with the support of OFB, we studied the feasibility to add a soil biodiversity survey (RMQS-Biodiversity) to the already existing French soil quality monitoring network (RMQS). It is a systemic monitoring based on a 16*16 km grid where the sampling is done on a plot at the center of the mesh, which could belong to different …
Next-generation modelling of community work and structural social work in Finland
2021
The recently reformed Finnish Social Welfare Act obligates public social work to enact structural social work, and to address the community- and structural-level social problems behind individual cases. This article examines how community work and structural social work are conceived by early career social workers. The empirical data consists of 26 project plans by social work Master’s students studying in a working life-based part-time programme. The data includes designs for community work or structural social work to be applied in practice to address a real social problem or issue identified by the students in their working environment. The designs are analysed by content analysis and re…
Frame analysis of psychotherapists’ perspectives on the development of psychological disorders
2021
AbstractThe development of psychological disorders has been explained by several psychological theories and remains under debate. Psychotherapists, however, have insights into the emergence and development of psychological disorders that stem from both theory and practice. The constantly evolving field of psychotherapy prompts reconsideration, specifically when psychotherapists’ views on the development of disorders impacts their treatment approach. In addition, theoretical orientation and years of clinical experience, while known to influence psychotherapists’ viewpoints also merit further study. Applying Erving Goffman’s frame analysis, semi structured interviews with psychotherapists wer…
Holmium(III) Single-Ion Magnet for Cryomagnetic Refrigeration Based on an MRI Contrast Agent Derivative
2021
The coexistence of field-induced blockage of the magnetization and significant magnetocaloric effects in the low-temperature region occurs in a mononuclear holmium(III) diethylenetriamine-N,N,N′,N″,N″-pentaacetate complex, whose gadolinium(III) analogue is a commercial MRI contrast agent. Both properties make it a suitable candidate for cryogenic magnetic refrigeration, thus enlarging the variety of applications of this simple class of multifunctional molecular nanomagnets.
Exposure to non-essential metals and albuminuria: exploring causal associations under a Mendelian randomization framework
2021
Vaccination en général et vaccination anti-COVID
2021
This book presents a societal research analysis of an exploratory study of the general public concerning the obstacles to vaccination. It highlights the fact that sociological anchors would be determinant in the decision making regarding vaccination. This study more broadly invites us to consider modern and post-modern anchors as possible determinants in the positions of individuals in relation to various subjects of science-society.
Verkörperung: Bild und Experiment bei Edgar Wind und die aktuelle Lage der morphologischen Forschung
2021
Edgar Wind’s The Experiment and Metaphysics examines, in the sense of Goethe’s morphological project, the common structures of scientific and artistic thinking in the light of the reflective value of the image and the technological processes of research and construction of reality. In Wind’s philosophy of em- bodiment the image plays a role in the artistic field comparable to the function of experiments in science. The picture is neither a ‘copy’ nor just a ‘part’ of reality, but rather an ‘embodiment’: at the same time the ‘result’ of human activity and a ‘condition’ for all interpretation of the world. It opens up as an embodiment to a temporality which is not just linear but ‘configured’…
Impact of maternal nutritional status during pregnancy on the associations between persistent organic pollutants and childhood overweight
2021
Carlo Goldoni
2021
International audience; « On ne peut nier que je sois né sous l'influence d'une étoile comique, puisque ma vie même a été une comédie ». Picaresque, cette vie de Carlo Goldoni nous fait entrer de plain-pied dans la folle et fascinante société vénitienne du XVIIIe siècle, puis à la cour de Louis XVet de Louis XVI. Rien d'étonnant pour ce Molière italien, ancêtre de la comédie néo-réaliste des Dino Risi, Vittorio de Sica et autres Pietro Germi...
GTF2I Mutation in Thymomas: Independence From Racial-Ethnic Backgrounds. An Indian/German Comparative Study
2021
Thymomas are the most frequent adult mediastinal cancers. Their etiology is unknown and their pathogenesis poorly understood. Racial, ethnic and environmental factors influence tumorigenesis in many cancers, but their role in thymomas remains unclear to date. In this study that included pretreatment thymoma cases from India and Germany (n = 37 and n = 77, respectively) we compared i) the prevalence of the thymoma-specific chromosome 7 c.74146970T > A mutation of the GTF2I gene in type A and AB thymomas; ii) epidemiological features; and iii) the frequency of myasthenia gravis (MG). Due to a known predominance of GTF2I mutation in A and AB histotypes, we included only a marginal numbe…
Knot placement in the Distributed non-linear lag models (DNLM) framework
2021
Perioperative Management of Pheochromocytoma: From a Dogmatic to a Tailored Approach
2021
Background: Perioperative management of pheochromocytoma (PCC) remains under debate. Methods: A bicentric retrospective study was conducted, including all patients who underwent laparoscopic adrenalectomy for PCC from 2000 to 2017. Patients were divided into two groups: Group 1 treated with alpha-blockade, and Group 2, without alfa-blockers. The primary end point was the major complication rate. The secondary end points were: the need for advanced intra-operative hemostasis, the admission to the intensive care unit (ICU), the length of stay (LOS), systolic (SBP), and diastolic blood pressure (DBP). Univariate and multivariate analysis was conducted. A p-value <
ASPHER Statement
2021
Submitted by Agostinho Macau (arm@ucp.pt) on 2021-09-14T08:06:58Z No. of bitstreams: 1 ijph_66_1604361.pdf: 553290 bytes, checksum: 213f7a1eaedc390557eeae306bfc3262 (MD5) Made available in DSpace on 2021-09-14T08:06:58Z (GMT). No. of bitstreams: 1 ijph_66_1604361.pdf: 553290 bytes, checksum: 213f7a1eaedc390557eeae306bfc3262 (MD5) Previous issue date: 2021-08-23 info:eu-repo/semantics/publishedVersion
Treatment concepts of horizontally deficient ridges-A retrospective study comparing narrow-diameter implants in pristine bone with standard-diameter …
2021
OBJECTIVES To compare clinical and radiological outcomes of narrow-diameter implants (NDI) placed in pristine bone to standard-diameter implants placed in combination with horizontal bone augmentation procedures (SDI+A) for horizontally deficient alveolar ridges. MATERIAL AND METHODS For this retrospective study, the outcome of 597 NDI (∅ 3.3 mm, 272 patients), inserted in pristine bone, were compared with 180 SDI (∅ 4.1 mm, 83 patients), inserted in combination with horizontal augmentation procedures. Oral health-related quality of life was assessed in patients available for recall. RESULTS After a mean follow-up of 37.6 ± 40 months for the NDI and of 42.4 ± 49 months for the SDI+A, surviv…
High-Mobility Ambipolar Magnetotransport in Topological Insulator Bi2Se3 Nanoribbons
2021
Nanoribbons of topological insulators (TIs) have been suggested for a variety of applications exploiting the properties of the topologically protected surface Dirac states. In these proposals it is crucial to achieve a high tunability of the Fermi energy, through the Dirac point while preserving a high mobility of the involved carriers. Tunable transport in TI nanoribbons has been achieved by chemical doping of the materials so to reduce the bulk carriers' concentration, however at the expense of the mobility of the surface Dirac electrons, which is substantially reduced. Here we study bare ${\mathrm{Bi}}_{2}{\mathrm{Se}}_{3}$ nanoribbons transferred on a variety of oxide substrates and dem…
Spanish riders law and the right to be informed about the algorithm
2021
The Spanish Government has introduced a regulation which establishes: i) the presumption of employment in digital delivery platforms, and ii) the right of workers’ representatives to be informed about the parameters, rules and instructions on which the algorithms that may have an impact on working conditions are based. This article describes the new law and analyses the novelty of this regulation and its expected impact. The main conclusion is that with this law the Spanish legislator is seeking to clarify that the new technological options – digital algorithms and platforms – are simply the means of performing an economic activity and therefore people who render services within their scop…
A linear regression-based machine learning pipeline for the discovery of clinically relevant correlates of gait speed reserve from multiple physiolog…
2021
Frailty in older adults is characterized by reduced physiological reserve. Gait speed reserve (GSR: maximum minus usual gait speed) could help identify frailty and act as a proxy for physiological reserve. Utilizing data from 2397 participants aged 50+ from wave 3 of The Irish Longitudinal Study on Ageing, we developed a stepwise linear regression-based machine learning pipeline to select the most important GSR predictors from 34 manually selected features across multiple domains. Variables were selected one at a time such that they maximized the mean adjusted r-squared score from a 5-fold cross-validation. A peak score of (0.16 +/- 0.03) was achieved with 14 variables (giving adjusted-r-sq…
Dual-stage and dual-deficit? Word recognition processes during text reading across the reading fluency continuum
2021
AbstractCentral questions in the study of visual word recognition and developmental dyslexia are whether early lexical activation precedes and supports decoding (a dual-stage view) or not (dual-route view), and the locus of deficits in dysfluent reading. The dual-route view predicts early word frequency and length interaction, whereas the dual-stage view predicts word frequency effect to precede the interaction effect. These predictions were tested on eye movements data collected from (n = 152) children aged 9–10 among whom reading dysfluency was overrepresented. In line with the dual-stage view, the results revealed an early word frequency effect in first fixation duration followed by robu…
Exploring the role of cosmological shock waves in the Dianoga simulations of galaxy clusters
2021
Cosmological shock waves are ubiquitous to cosmic structure formation and evolution. As a consequence, they play a major role in the energy distribution and thermalization of the intergalactic medium (IGM). We analyze the Mach number distribution in the Dianoga simulations of galaxy clusters performed with the SPH code GADGET-3. The simulations include the effects of radiative cooling, star formation, metal enrichment, supernova and active galactic nuclei feedback. A grid-based shock-finding algorithm is applied in post-processing to the outputs of the simulations. This procedure allows us to explore in detail the distribution of shocked cells and their strengths as a function of cluster ma…
Evaluation of Epigenetic and Radiomodifying Effects during Radiotherapy Treatments in Zebrafish
2021
Radiotherapy is still a long way from personalizing cancer treatment plans, and its effectiveness depends on the radiosensitivity of tumor cells. Indeed, therapies that are efficient and successful for some patients may be relatively ineffective for others. Based on this, radiobiological research is focusing on the ability of some reagents to make cancer cells more responsive to ionizing radiation, as well as to protect the surrounding healthy tissues from possible side effects. In this scenario, zebrafish emerged as an effective model system to test for radiation modifiers that can potentially be used for radiotherapeutic purposes in humans. The adoption of this experimental organism is fu…
Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol.
2021
Postmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a biomarker of wine consumption, with anthropometric (weight, waist circumference, body mass index (BMI), and waist-to-height ratio), blood pressure, and biochemical variables (blood glucose and lipid profile) that may be affected during the menopausal transition. This sub-study of the PREDIMED (Prevención con Dieta Mediterránea) trial included a sample of 230 women aged 60–80 years with high cardiovascular risk at baseline. Urine samples were diluted and filtered, and tartari…
Radiation-Induced Stable Radicals in Calcium Phosphates: Results of Multifrequency EPR, EDNMR, ESEEM, and ENDOR Studies
2021
This article presents the results of a study of radiation-induced defects in various synthetic calcium phosphate (CP) powder materials (hydroxyapatite—HA and octacalcium phosphate—OCP) by electron paramagnetic resonance (EPR) spectroscopy at the X, Q, and W-bands (9, 34, 95 GHz for the microwave frequencies, respectively). Currently, CP materials are widely used in orthopedics and dentistry owing to their high biocompatibility and physico-chemical similarity with human hard tissue. It is shown that in addition to the classical EPR techniques, other experimental approaches such as ELDOR-detected NMR (EDNMR), electron spin echo envelope modulation (ESEEM), and electronnuclear double resonance…
Psychometric Properties of the Spanish Version of the Online Sexual Addiction Questionnaire: An Exploratory Study Using a Sample of Convicted Sex Off…
2021
Pembesaran Ikan Nila (Oreochromis niloticus) pada Budidaya Sistem Resirkulasi Menggunakan Filtrasi Tanaman Hydrilla verticillata dan Ceratophyllum de…
2021
Penelitian ini mengkombinasikan tanaman Hydrilla verticillata dengan Ceratophyllum demersum sebagai filter pada budidaya ikan Nila sistem resirkulasi. Tujuan penelitian yaitu untuk mengetahui tingkat pertumbuhan ikan Nila pada budidaya sistem resirkulasi. Filtrasi yang digunakan pada budidaya sistem resirkulasi yaitu tanaman H. verticillata dan C. demersum. Metode penelitian menggunakan rancangan acak lengkap (RAL). Adapun parameter yang diamati berupa kelangsungan hidup ikan, pertumbuhan mutlak, laju pertumbuhan spesifik (SGR), Feed Conversion Ratio (FCR) dan kualitas air. Kelangsungan hidup ikan selamat pemeliharaan yaitu 100%. Pertumbuhan bobot mutlak individu berkisar 8.76 sampai 16.6 g…
Impacto del viaje de Freire a Valencia
2021
In the publications of Freire's trip, errors are detected that makes invisible both its impact and those who made it possible. An analysis of the documentation, 6 interviews with people who made the trip possible, 6 with professionals and 2 with family members in Valencia who are transforming their schools and 2 dialogical observations have been carried out. The results make it clear: 1) Those who proposed this trip both to Freire and to the Regional Ministry are Flecha and Jesús Gomez 'Pato'. 2) The reason is the approval by the Valencian Parliament of the Law on Adult Education, whose 'Report and draft for its preliminary project' had been entrusted to Flecha, who was hired to elaborate i…
Evaluasi Penerapan Konsep Ekowisata di Kampung Wisata Arborek, Raja Ampat
2021
Evaluation the application of the ecotourism concept in a tourist destination is considered important in maintaining the sustainability of tourism management. Arborek tourism village is one of the best tourist villages in Raja Ampat so that the selection as a research location is considered appropriate to evaluate the application of the ecotourism concept to every tourist activity so that the existence of Arborek Tourism Village is maintained. The purpose of this study is to evaluate the application of the ecotourism concept in the Arborek tourist village. The data was taken using a closed ended questionnaire and then analyzed using the One Score One Criteria Scoring System method. The resu…
Biomaterial-Assisted Anastomotic Healing: Serosal Adhesion of Pectin Films
2021
Anastomotic leakage is a frequent complication of intestinal surgery and a major source of surgical morbidity. The timing of anastomotic failures suggests that leaks are the result of inadequate mechanical support during the vulnerable phase of wound healing. To identify a biomaterial with physical and mechanical properties appropriate for assisted anastomotic healing, we studied the adhesive properties of the plant-derived structural heteropolysaccharide called pectin. Specifically, we examined high methoxyl citrus pectin films at water contents between 17–24% for their adhesivity to ex vivo porcine small bowel serosa. In assays of tensile adhesion strength, pectin demonstrated significant…
A Dataset of Annotated Omnidirectional Videos for Distancing Applications
2021
Omnidirectional (or 360°) cameras are acquisition devices that, in the next few years, could have a big impact on video surveillance applications, research, and industry, as they can record a spherical view of a whole environment from every perspective. This paper presents two new contributions to the research community: the CVIP360 dataset, an annotated dataset of 360° videos for distancing applications, and a new method to estimate the distances of objects in a scene from a single 360° image. The CVIP360 dataset includes 16 videos acquired outdoors and indoors, annotated by adding information about the pedestrians in the scene (bounding boxes) and the distances to the camera of some point…
Seasonality in Tourism: Do Senior Programs Mitigate It?
2021
Seasonality is a widely recognised and accredited phenomenon known to cause an imbalance in tourism activity throughout the year, prompting tourist destinations, both public and private, to consider how best to plan the use of their resources. One way of mitigating the economic imbalances that seasonality can cause is to find strategies for seasonal adjustment, such as travel programmes aimed at the elderly. This paper analyses the seasonality of tourism activity in some EU countries, and in particular in Spain. Different indicators are used to compare the results and carry out a sensitivity analysis. The study then focuses on tourism programmes for the elderly in Spain to see whether this …
Bacterial Viruses Subcommittee and Archaeal Viruses Subcommittee of the ICTV: Update of taxonomy changes in 2021
2021
In this article, we – the Bacterial Viruses Subcommittee and the Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) – summarise the results of our activities for the period March 2020 – March 2021. We report the division of the former Bacterial and Archaeal Viruses Subcommittee in two separate Subcommittees, welcome new members, a new Subcommittee Chair and Vice Chair, and give an overview of the new taxa that were proposed in 2020, approved by the Executive Committee and ratified by vote in 2021. In particular, a new realm, three orders, 15 families, 31 subfamilies, 734 genera and 1845 species were newly created or redefined (moved/promoted). Supplem…
High-resolution UAV imagery for field olive (Olea europaea L.) phenotyping
2021
Remote sensing techniques based on images acquired from unmanned aerial vehicles (UAVs) could represent an effective tool to speed up the data acquisition process in phenotyping trials and, consequently, to reduce the time and cost of the field work. In this study, we assessed the ability of a UAV equipped with RGB-NIR cameras in highlighting differences in geometrical and spectral canopy characteristics between eight olive cultivars planted at different planting distances in a hedgerow olive orchard. The relationships between measured and estimated canopy height, projected canopy area and canopy volume were linear regardless of the different cultivars and planting distances (RMSE of 0.12 m…
The Two Types of Oxygen Interstitials in Neutron‐Irradiated Corundum Single Crystals: Joint Experimental and Theoretical Study
2021
Thinking spirituality today with C.G. Jung
2021
International audience
Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring.
2021
Epidemiological studies, which can have inherent methodological limitations, are used to study the relation between endocrine disrupting chemicals and autism spectrum disorder. The objective is to systematically review the treatment of methodological limitations and assess the quality and strength of the findings in the available literature. The quality and strength of the evidence were evaluated using the Navigation Guide Systematic Review Methodology. The overall quality and strength of the available studies were “moderate” and “limited,” respectively. Risk of bias due to the methodological limitations regarding the exclusion of potential confounding factors and the lack of accuracy of e…