showing 36 of ~574560 from 574555 documents
Proposed Environmental Risk Management Elements in a Carpathian Valley Basin, within the Roşia Montană European Historical Mining Area
2021
Non-ferrous metals mining activities have long accompanied people, and began in the study area of South East Europe over 2000 years ago. The environment quality is significantly affected by both historic mining activities and contemporary impacts. All these problems, inducing synergic negative effects on local organism communities, have created a chronic state of pollution. The Corna Valley has one of the oldest historical human impacts in Romania due to the influence of mining. Fish and benthic macroinvertebrates have exhibited significant responses to long term mining effects on lotic systems. The analysis of macroinvertebrate communities, correlated with the lack of fish and some biotope…
Ontogenetic development of the holocephalan dentition: Morphological transitions of dentine in the absence of teeth.
2021
Among the cartilaginous fishes (Chondrichthyes), the Holocephali are unique in that teeth are absent both in ontogeny and adult regenerative growth. Instead, the holocephalan dentition of ever-growing nonshedding dental plates is composed of dentine, trabecular in arrangement, forming spaces into which a novel hypermineralized dentine (whitlockin) is deposited. These tissue features form a variety of specific morphologies as the defining characters of dental plates in the three families of extant holocephalans. We demonstrate how this morphology changes through ontogenetic development with continuity between morphologies, through successive growth stages of the dentition represented by the …
Heat Pump Induction Motor Faults Caused by Soft Starter Topology — Case Study
2021
This paper presents a case study of electrical machine faults, emerging in heat pump systems. In Nordic countries, heat pumps have been gaining popularity during the past years and have become one of the leading ways of heating in households and smaller public buildings. Although not a very complicated setup, the devices used are still prone to unexpected failures, especially if wrongly chosen, installed or maintained. The paper presents a study conducted on five real-life cases with very similar outcomes and failure modes. The setup of the systems is explained, faults are listed and presented, causes of the faults including modeling and measurement data are provided. The suggestions are gi…
Epidemiological trends and trajectories of MAFLD-associated hepatocellular carcinoma 2002-2033: The ITA.LI.CA database
2021
BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) represents a new inclusive definition of the whole spectrum of liver diseases associated to metabolic disorders. The main objective of this study was to compare patients with MAFLD and non-MAFLD with hepatocellular carcinoma (HCC) included in a nationally representative cohort.MethodsWe analysed 6882 consecutive patients with HCC enrolled from 2002 to 2019 by 23 Italian Liver Cancer centres to compare epidemiological and future trends in three subgroups: pure, single aetiology MAFLD (S-MAFLD); mixed aetiology MAFLD (metabolic and others, M-MAFLD); and non-MAFLD HCC.ResultsMAFLD was diagnosed in the majority of patients w…
Nanotechnology for Natural Medicine: Formulation of Neem Oil Loaded Phospholipid Vesicles Modified with Argan Oil as a Strategy to Protect the Skin f…
2021
Neem oil, a plant-derived product rich in bioactives, has been incorporated in liposomes and hyalurosomes modified by adding argan oil and so called argan-liposomes and argan-hyaluro-somes. Argan oil has also been added to the vesicles because of its regenerative and protective effects on skin. In the light of this, vesicles were specifically tailored to protect the skin from oxidative stress and treat lesions. Argan-liposomes were the smallest vesicles (~113 nm); the addition of sodium hyaluronate led to an increase in vesicle size (~143 nm) but it significantly improved vesicle stability during storage. In vitro studies confirmed the free radical scavenging activity of formula-tions, irre…
Regional Disparities and Spatial Dependence of Bankruptcy in Spain
2021
Firm survival, bankruptcy, and turnaround are of great interest nowadays. Bankruptcy is the ultimate resource for a company to survive when it is affected by a severe decline. Thus, determinants of firm turnaround and survival in the context of bankruptcy are of interest to researchers, managers, and policy-makers. Prior turnaround literature has broadly studied firm-specific factors for turnaround success. However, location-specific factors remain relatively unstudied despite their increasing relevance. Thus, this paper aims to evaluate the existence of spatial dependence on the outcome of the bankruptcy procedure. Economic geography and business literature suggest that location matters an…
Existence of a traveling wave solution in a free interface problem with fractional order kinetics
2021
Abstract In this paper we consider a system of two reaction-diffusion equations that models diffusional-thermal combustion with stepwise ignition-temperature kinetics and fractional reaction order 0 α 1 . We turn the free interface problem into a scalar free boundary problem coupled with an integral equation. The main intermediary step is to reduce the scalar problem to the study of a non-Lipschitz vector field in dimension 2. The latter is treated by qualitative topological methods based on the Poincare-Bendixson Theorem. The phase portrait is determined and the existence of a stable manifold at the origin is proved. A significant result is that the settling time to reach the origin is fin…
Time to safely omit bladder cuff removal for low-risk upper tract urothelial carcinoma
2021
PENGARUH MODIFIKASI PERMAINAN FUTBAS TERHADAP KETEPATAN PASSING BOLA PADA SISWA EKSTRAKURIKULER FUTSAL SMA MUHAMMADIYAH 4 SURABAYA
2021
Penelitian ini bertujuan untuk mengetahui seberapa besar peningkatan ketepatan passing siswa pada ekstra kurikuler futsal dengan menggunakan metode futbas. Pelatihan ketepatan futsal dengan metode modifikasi ini untuk mempermudah guru ekstra futsal dan sebagai salah satu alternative metode modifikasi yang bisa digunakan oleh pelatih atau guru dalam aktivitas pembelajaran ekstra futsal. Penelitian ini menggunakan desain true experimental. Jadi cirinya ialah adanya kelompok kontrol dan sampel dipilih secara random. Dalam desain ini terdapat dua kelompok yang dipilih secara random, kemudian diberi pretest untuk mengetahui keadaan awal adakah perbedaan antara kelompok eksperimen dan kelompok ko…
Phosphorylation of meprin β controls its cell surface abundance and subsequently diminishes ectodomain shedding
2021
Meprin β is a zinc-dependent metalloprotease exhibiting a unique cleavage specificity with strong preference for acidic amino acids at the cleavage site. Proteomic studies revealed a diverse substrate pool of meprin β including the interleukin-6 receptor (IL-6R) and the amyloid precursor protein (APP). Dysregulation of meprin β is often associated with pathological conditions such as chronic inflammation, fibrosis, or Alzheimer's disease (AD). The extracellular regulation of meprin β including interactors, sheddases, and activators has been intensively investigated while intracellular regulation has been barely addressed in the literature. This study aimed to analyze C-terminal phosphorylat…
Transvaginal rectocele repair reinforced with biological mesh - a video vignette.
2021
Detection of γ‐hydroxybutyric acid‐related acids in blood plasma and urine: Extending the detection window of an exogenous γ‐hydroxybutyric acid inta…
2021
In crimes facilitated by γ-hydroxybutyric acid (GHB) administration, the frequent occurrence of anterograde amnesia of the victims as well as the short detection window and variations of endogenous GHB concentrations complicate obtaining analytical proof of GHB administration. Because elevated endogenous organic acid concentrations have been found in the urine of patients with succinic semialdehyde deficiency (leading to accumulation of GHB in human specimens) and after GHB ingestion, we searched for an alternative way to prove GHB administration via detection of elevated organic acid concentrations in blood plasma and urine. We collected blood and urine samples from narcolepsy patients (n …
Students’ Interpretations of a Persuasive Multimodal Video About Vaccines
2021
The present study investigated students’ (N = 404) interpretations of the main message and use of modes in a persuasive multimodal video on vaccines. It also examined whether students’ topic knowledge, language arts grades, and self-identified gender were associated with their interpretations. Students analyzed a YouTube video in which two entertainers demonstrated the importance of vaccinating children. Students’ interpretations of the usefulness of vaccines varied in terms of quality of reasoning, which was associated with students’ topic knowledge. Notably, many students’ interpretations of the use of modes were incomplete, or they did not even mention certain modes in their response. Th…
Sense of coherence and burnout in nursing home workers during the COVID‐19 pandemic in Spain
2021
Abstract Care staff in nursing homes work in a challenging environment, and the COVID‐19 pandemic has exacerbated those challenges in an unprecedented way. On the other hand, the sense of coherence (SOC) is a competence that could help these professionals perceive the situation as understandable, manageable and meaningful. This study aims to analyse the extent to which potential risk and protective factors against burnout have affected nursing home workers during the COVID‐19 pandemic and to assess the contribution of these factors to their burnout. Three hundred forty professionals who worked in nursing homes in Spain completed a survey and reported on their sociodemographic characteristic…
How Much Money Do You Need to Feel Taller? Impact of Money on Perception of Body Height
2021
Body height is considered to be one of the most important reproductive signals. However, there are only a few publications on what influences the sense of whether we assess ourselves as tall or short. In the present contribution, the psychological impact of money on the evaluation of a person’s own height was tested. We performed two experimental studies in which the respondents had contact with different amounts of money and were asked to evaluate their body height with the use of a laser pointer. The first experiment (N = 61) showed that contact with money significantly increased subjective height evaluation, and the effect was independent of participants’ real body height. The second exp…
Modeling Political Corruption in Spain
2021
Political corruption is a universal phenomenon. Even though it is a cross-country reality, its level of intensity and the manner of its effect vary worldwide. In Spain, the demonstrated political corruption cases that have been echoed by the media in recent years for their economic, judicial and social significance are merely the tip of the iceberg as regards a problem hidden by many interested parties, plus the shortage of the means to fight against it. This study models and quantifies the population at risk of committing political corruption in Spain by identifying and quantifying the drivers that explain political corruption. Having quantified the problem, the model allows changes to be …
false
2021
In addition to their chemical composition various physical properties of synthetic bone substitute materials have been shown to influence their regenerative potential and to influence the expression of cytokines produced by monocytes, the key cell-type responsible for tissue reaction to biomaterials in vivo. In the present study both the regenerative potential and the inflammatory response to five bone substitute materials all based on β-tricalcium phosphate (β-TCP), but which differed in their physical characteristics (i.e., granule size, granule shape and porosity) were analyzed for their effects on monocyte cytokine expression. To determine the effects of the physical characteristics of …
Mortality attributable to COVID-19 in nursing home residents: a retrospective study
2021
AbstractAimCoronavirus-19 disease (COVID-19) is a widespread condition in nursing home (NH). It is not known whether COVID-19 is associated with a higher risk of death than residents without COVID-19. Therefore, the aim of this study was to assess whether COVID-19 is associated with a higher mortality rate in NH residents, considering frailty status assessed with the Multidimensional Prognostic Index (MPI).MethodsIn this retrospective study, made in 31 NHs in Venice, Italy, the presence of COVID-19 was ascertained with a nasopharyngeal swab. Frailty was evaluated using the MPI, modified according to the tools commonly used in our NHs. A Cox’s regression analysis was used reporting the resul…
Une tendance inachevée vers l’urbanisation en Celtique nord-alpine (575-450 a.C.)
2021
International audience
Ki-67 immunoexpression and radiological assessment of necrosis improves accuracy of conventional and modified core biopsy systems in predicting the f…
2021
Based on the French Federation Nationale des Centers de Lutte Contre le Cancer (FNCLCC) grading system, this study assesses the accuracy of conventional and modified core biopsy (CB) systems in predicting the final grade (low vs high) assigned to the resected specimen. Substituting Ki-67 immunoexpression for mitotic count, and radiological for histological assessment of necrosis, we used two modified FNCLCC CB grading systems: (1) Ki-67 immunoexpression alone, and (2) Ki-67 plus radiological assessment of necrosis. We graded 199 soft tissue sarcomas (STS) from nine centers, and compared the results for the conventional (obtained from local histopathology reports) and modified CB systems wit…
Political community resilience in declining rural areas in Finland
2021
Abstract In this article, we study how declining rural communities build political resilience in Finland. Community resilience is an adaptive process through which rural communities try to maintain their viability in changed circumstances. This process does not entail a submissive attitude, but rather active agency and an effort to influence matters concerning the community’s well-being. We focus on the political dimension of resilience by identifying different local tactics that rural communities adopt to promote their own development following municipal mergers. We classify these tactics into three categories: cooperation, conflict and community-led development. The significant difference…
Discursive framing and organizational venues: mechanisms of artificial intelligence policy adoption
2021
The purpose of this article is twofold: to theoretically assess ideational and organizational explanatory factors in the adoption of artificial intelligence policies; and to examine the extent to which the European Union has managed to facilitate a coordinated artificial intelligence policy in the Nordic countries. The study utilizes a mixed-methods approach based on systematic web searching, systematic policy document analysis and key informant semi-structured interviews. The study finds that the European Union has utilized framing-based strategies to set an agenda for a coordinated European artificial intelligence policy. Moreover, the strategy has affected member-state artificial intell…
Castniidae of the Museum of Natural History of the University of Wrocław: new findings from Friedrich Wilhelm Niepelt's collection with comments on K…
2021
Further results of our research into the Giant Butterfly-Moths (Castniidae) of the Museum of Natural History (University of Wrocław) are presented. Castniids of the Niepelt collection had previously been reviewed. However, while curating other sections of the Lepidoptera collection, we discovered 18 misplaced specimens belonging to nine taxa of Castniidae, several of them bearing typical labels by Niepelt. Among them, two are of particular interest, insofar as they are associated with the world-class botanists August Weberbauer (1871–1948) and Karl Adolf Georg Lauterbach (1864–1937).
La corédaction en système juridique plurilingue et le figement du sens. Une analyse sémantique et traductologique des ordonnances suisses liées à la …
2021
National audience; La langue juridique est connue pour ses diverses technicités et subtilités qui ont pour effet de souvent écarter la traduction juridique des autres domaines spécialisés. Outre le simple transfert linguistique du texte, ainsi que des caractéristiques lexicales, syntaxiques et pragmatiques spécifiques aux langues concernées par l’opération de traduction (cf. Cao 2007), la comparaison des deux systèmes juridiques en jeu se révèle, dans la plupart des cas, être un impératif (cf. Sandrini 1999).Même à la lumière de la pandémie actuelle qui a conduit les gouvernements à prendre rapidement des mesures visant à contenir la propagation du virus, les principes juridiques fondamenta…
Lipocalins in Arthropod Chemical Communication.
2021
Abstract Lipocalins represent one of the most successful superfamilies of proteins. Most of them are extracellular carriers for hydrophobic ligands across aqueous media, but other functions have been reported. They are present in most living organisms including bacteria. In animals they have been identified in mammals, molluscs, and arthropods; sequences have also been reported for plants. A subgroup of lipocalins, referred to as odorant-binding proteins (OBPs), mediate chemical communication in mammals by ferrying specific pheromones to the vomeronasal organ. So far, these proteins have not been reported as carriers of semiochemicals in other living organisms; instead chemical communicatio…
Interventions aimed at reducing obsessive-compulsive symptoms in people with autism spectrum disorder: A review
2021
espanolEl trastorno del espectro autista (TEA) es un trastorno del neurodesarrollo caracterizado por deficits en la comunicacion e interaccion social y por comportamientos restrictivos y repetitivos. Presenta una elevada comorbilidad con otros trastornos, de hasta un 37% con el trastorno obsesivo compulsivo (TOC) en pacientes jovenes. El TOC se caracteriza por pensamientos e ideas recurrentes que llevan a la persona a realizar acciones compulsivas para disminuir el nivel de ansiedad que estos pensamientos le generan. Este trabajo presenta una revision de los metodos psicologicos de intervencion utilizados, asi como de la efectividad de los mismos, en la reduccion de los sintomas del TOC com…
Methodological Aspects for the Implementation of the Air Pesticide Control and Surveillance Network (PESTNet) of the Valencian Region (Spain)
2021
A large amount of pesticide, applied mainly during agricultural practice, is released into the atmosphere, decreasing air quality and potentially causing public health problems. The Valencian region, after Andalusia, is the Spanish region with the highest consumption of pesticides owing to its large areas of agricultural land and the existence of crops that require intensive use of pesticides. In this work, we describe the sampling and analytical tools developed in the last decade and their transference to the Regional Department for Environment, where the main objective of the research was the creation and implementation of an Air pesticide control and surveillance network (PESTNet) in the…
Bio‐based Materials
2021
Astronomiskais aspekts sengrieķu tekstos
2021
Lekcijā tika aplūkoti atsevišķi debess ķermeņu un dabas parādību pieminējuma un atainojuma aspekti Eiropas senākajos dzejas tekstos, uzmanības lokā uzsverot sengrieķu literatūras sākotni ar Homēra un Hēsioda tekstiem un arhaiskā perioda liriku, kā arī hellēnisma laika dzejnieka Arāta poēmu “Parādības” (sengrieķu val. Φαινόμενα), kas šobrīd tiek tulkota un atdzejota latviešu valodā. Izskanēja arī Arāta poēmas atdzejojuma fragmenti.
Wood‐based Packaging
2021
Structural and Electrochemical Analysis of CIGS: Cr Crystalline Nanopowders and Thin Films Deposited onto ITO Substrates
2021
A new approach for the synthesis of nanopowders and thin films of CuInGaSe2 (CIGS) chalcopyrite material doped with different amounts of Cr is presented. The chalcopyrite material CuInxGa1 − xSe2 was doped using Cr to form a new doped chalcopyrite with the structure CuInxCryGa1 − x − ySe2, where x = 0.4 and y = 0.0, 0.1, 0.2, or 0.3. The electrical properties of CuInx CryGa1 − x − ySe2 are highly dependent on the Cr content and results show these materials as promising dopants for the fabrication thin film solar cells. The CIGS nano-precursor powder was initially synthesized via an autoclave method, and then converted into thin films over transparent substrates. Both crystalline precursor p…
Las Naciones Unidas frente a una década de conflicto e impunidad en Yemen
2021
El conflicto del Yemen está cerca de cumplir 10 años. En el mismo, la ONU ha llevado a cabo una actividad constante de intervención, sin que hasta el momento ninguno de los mecanismos puestos en marcha haya conseguido su objetivo fundamental de detener el conflicto y acabar con la impunidad a la que se ve condenada su población civil. Ante la mayor crisis humanitaria acaecida en lo que va de siglo, este estudio se plantea la labor de la Organización y qué respuesta podría ser la adecuada. The conflict in Yemen is nearing its 10th year. The UN has been constantly intervening in the conflict, but so far none of the mechanisms put in place has achieved its fundamental objective of stopping the…
MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer
2021
SummaryWe hypothesize that dosage compensation of critical genes arises from systems-level properties for cancer cells to withstand the negative effects of aneuploidy. We identified several candidate genes in cancer multi-omics data and developed a biocomputational platform to construct a mathematical model of their interaction network with miRNAs and transcription factors, where the property of dosage compensation emerged for MYC and was dependent on the kinetic parameters of its feedback interactions with three micro-RNAs. These circuits were experimentally validated with a novel genetic tug-of-war technique by overexpressing an exogenous MYC leading to over-expression of the three microR…
Elliptic Flow of Electrons from Beauty-Hadron Decays in Pb-Pb Collisions at √sNN = 5.02 TeV
2021
The elliptic flow of electrons from beauty hadron decays at midrapidity (|y|<0.8) is measured in Pb-Pb collisions at √sNN=5.02 TeV with the ALICE detector at the LHC. The azimuthal distribution of the particles produced in the collisions can be parametrized with a Fourier expansion, in which the second harmonic coefficient represents the elliptic flow, v2. The v2 coefficient of electrons from beauty hadron decays is measured for the first time in the transverse momentum (pT) range 1.3–6 GeV/c in the centrality class 30%–50%. The measurement of electrons from beauty-hadron decays exploits their larger mean proper decay length cτ≈500 μm compared to that of charm hadrons and most of the other …
Dynamic relations among COVID-19-related media exposure and worries during the COVID-19 pandemic
2021
Objectives: This study investigated how COVID-19-related media exposure during the COVID-19 crisis was related to same-day and next-day COVID-19-related worries. Design: A 21-day diary study was conducted between late March and late April 2020 in Germany. Main Outcome Measures: Hypotheses were tested in a sample of 561 participants (Mage = 42.79, SDage = 6.12). Every evening, participants indicated their exposure to COVID-19-related media (e.g., TV, print, online) and their COVID-19-related worries. Results: Same-day analyses showed that participants reported more COVID-19-related worries on days with higher exposure to COVID-19-related media. Dynamical structural equation models provided e…
Invasive Aliens in Italy: Enumeration, History, Biology and Their Impact
2021
Italy includes two large islands, Sardinia and Sicily, and a peninsula separated from the European continent by the Alpine Arch. At national level ISPRA (Instituto Superiore per la Protezione e la Ricerca Ambientale, Higher Institute for Environmental protection and research) is the instrument of the Ministry of Environment and for the Protection of the Territory and the Sea to carry out its mission, including the study, monitoring, and control of invasive alien species. Universities, Scientific Societies, and ONGs play a vital role in basic research. The interest in the study of alien plants is of a theoretical nature, as regards the migrations of living beings and interactions with native…