Psychopharmacological Drugs as Represented in the Press: Results of Systematic Analysis of Newspapers and Popular Magazines

1996

The representation of mental diseases and psychopharmacological drugs in the media, especially in the press, is thought to be of great impact on people's opinions on the subject. During the course of one year, all articles about psychopharmacological drugs and cardiac drugs published in nineteen German newspapers were collected. All statements, together with related aspects, reasons for prescription, individual details of the patient, effects and side-effects, were registered and classified according to a key. The results show that, in contrast to 13% of the articles about cardiac drugs, half of the reports about psychopharmacological drugs deal primarily with the problems of side-effects a…

Synthesis and characterisation of [(C5Me4R)2NbS2]2M complexes (M = Fe, Co; R = Me, Et) : organometallic tetrathiometalates with niobocene ligands

1996

Abstract Irradiation of Cp 2 ∗ Nb(η 2 S 2 )H (Cp ∗ = C 5 Me 5 ) 1a in the presence of Fe(CO) 5 gives the CO-free complex [Cp 2 ∗ NbS 2 ] 2 Fe 2a . The core of 2a contains an FeS 4 tetrahedron which is ligated by two niobocene ligands as shown by X-ray diffraction analysis. In the reaction of 1a or Cp 2 x Nb(η 2 S 2 )H (CP x = C 5 Me 4 Et) 1b with Co 2 (CO) 8 , compounds 3a and 3b of the same type are formed. Electrochemical studies of 2a and 3a,b show that they undergo three reversible 1e − steps. The oxidation of 3b exerts a considerable influence on its absorption spectrum. A qualitative EHMO analysis is in agreement with a strong delocalisation of electron density over the whole NbS 2 …

Critical currents and micro-structure in YBa2Cu3O7−δ thin films

1996

In an attempt to clarify the origin of the large critical current densitiesJ c observed in Laser Ablated and Sputtered YBa2Cu3O7−δ (YBCO) thin films, we make a systematic study of the low temperatureJ c in samples carefully analysed using STM and AFM.J c (B) is determined from torque-magnetometry performed in ring-patterned thin films. Epitaxial YBCO films nucleate in c-axis oriented single-crystalline islands with sizes ranging between 200 and 700 nm. We show thatJ c can be mainly explained by vortex pinning localised in the island boundaries.

Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices

1996

1. The effect of some xenobiotics on levels of selected cytochrome P450 (CYP) isoenzymes determined by Western immunoblotting and associated enzyme activities has been studied in 72-h cultured rat and human precision-cut liver slices. 2. In cultured rat liver slices, 0.5 mM sodium phenobarbitone (PB), 25 microM beta-naphthoflavone (BNF), and 20 micrograms/ml Aroclor 1254 (ARO) induced mixed-function oxidase enzyme activities. Western immunoblotting of liver slice microsomes was performed with antibodies to rat CYP1A2, 2B1/2 and 3A. Compared with 72-h control (dimethyl sulphoxide only treated) rat liver slice microsomes, PB induced CYP2B1/2 and 3A, BNF induced CYP1A2, and ARO induced CYP1A2,…

Second-order tensorial calibration for kinetic spectrophotometric determination

1996

Abstract Kinetic-diode array spectrophotometric detection, as well as other multichannel techniques when used in non-equilibrium conditions, constitute second-order instrumentation. The second-order response provided will be bilinear, under certain conditions even trilinear, thus allowing the use of the generalized rank annihilation method (GRAM) and the trilinear decomposition method (TLD). Both numerically simulated and experimental data were used to evaluate the performance of these calibration techniques. The conditions in which the ‘second-order advantage’ (the possibility of quantifying the analytes in the presence of unknown reactions or interferences) is preserved were investigated.…

Studies on mechanism and physico-chemical parameters at the origin of the cement setting II. Physico-chemical parameters determining the coagulation …

1996

The physico-chemical parameters determining the coagulation of cements grains previously identified as the first fundamental process of cement setting have been investigated in diluted suspensions using an adapted granulometric method. The analysis of the influence of the ionic concentration in solution on the coagulation reveals that calcium concentration is the parameter which determines the particle interactions. There exists a minimum critical concentration of calcium ions in solution which is required to occur the coagulation of cement particles and a dispersive effect appears for very high concentrations. The results are discussed in relation with DLVO theory and specific interactions.

Avoidant coping style and verbal-cardiovascular response dissociation

1996

Abstract This study explored the relationship between an avoidant coping style and three responses during three experimental periods (i.e., speech preparation, speech delivery, and recovery). One response was cardiovascular reactivity, the two other responses were subjective in nature: self-reports of anxiety and self-estimations of blood pressure. Subjects were 20 male and 20 female students who scored either in the upper third (i.e., high-avoiders) or lower third (i.e., low-avoiders) on cognitive avoidance (Krohne, 1989). When compared to subjects scoring low on avoidance, those high on avoidance showed greater systolic blood pressure (SBP) reactivity and evidenced verbal-autonomic respon…

Modelling of a Circular Shrinkage Fit in Taking into account of the Form Defect

1996

International audience

Irreducible Representations of Periodic Finitary Linear Groups

1996

Sahel droughts and Enso dynamics

1996

Correlations between summer Sahel rainfall and Southern Oscillation Index has increased during the last thirty years. At high frequency time scale (periods lower than 8 years), an intertropical Atlantic zonal divergent circulation anomaly is forced by the difference of sea surface temperature (SST) anomalies between the eastern equatorial parts of Pacific and Atlantic. This zonal connection worked well during most of the E1 Nino/Southern Oscillation (ENSO) events occurring after 1970; positive/negative SST anomalies in the eastern Pacific/Atlantic led to rainfall deficits over the whole West Africa. At low frequency time scale (periods greater than 8 years), positive SST anomalies in the In…

Epistemologia ed insegnamento della Chimica Fisica nel corso di laurea in Scienze Geologiche. Nota II. Analisi di specifici errori in geotermia e vul…

1996

Questa secondaNota e una discussione della casistica su cui sono fondate le conclusioni della prima. I casi sono: cio che appare come confusione tra energia e calore nelle valutazioni delle risorse geotermiche (ma che spesso e dovuta ad un’insufficiente descrizione dei sistemi coinvolti, naturali e non); erronee descrizioni dei dati di gradiente geotermico (stessa causa, ma dovute anche alla difficolta di applicare ai sistemi naturali definizioni della Fisica come quella di calore); i termometri chimici fondati su specie gassose (che possono essere valutati solo se i vincoli che eliminano l’indeterminazione delle funzioni di temperatura sono chiaramente definiti); la fondamentale questione …

Spatially resolved optical studies of F-center diffusion in KBr crystals.

1996

Spatially resolved optical studies of F-center diffusion during and after the photothermal F\ensuremath{\rightarrow}X color center conversion have been performed by optical scanning and holographic methods in electrolytically colored KBr crystals. Average velocities and diffusion coefficients of F centers have been determined for Gaussian and periodical spatial exposing light intensity distributions. A strong influence of the light intensity gradient has been found on F-center diffusion. It manifests itself by a rapid increase of the effective diffusion coefficient when the light intensity gradient is decreased. This behavior allowed us to explain the observed peculiarities of the holograph…

Tail and Head Group Interactions in Phospholipid Monolayers

1996

Abstract The order/disorder transition of the phospholipid 1,2-dihexadecyl-sn-glycero-3-phosphocholine and its derivatives was studied by X-ray reflection and thermodynamic measurements. We find that increasing the length of an ethylene oxide spacer (zero to three EO groups) between the phosphate group and the hydrophobic chains (i) induces a slight shift of the main transition, (ii) reduces the influence of the head groups on the chain lattice, and (iii) increases the head group length and promotes its hydration. For DH(EO)3PC in the ordered phase we find that the small phosphate groups (which are the main source of contrast in X-ray reflectivity) are homogeneously distributed within the h…

Decomposer animal communities in forest soil along heavy metal pollution gradient

1996

Responses of soil decomposer animals to heavy metal contamination and to concomitant changes in organic matter quality and quantity and in soil microbial biomasses have been studied along a pollution gradient from a Cu-Ni smelter. Samples have been taken separately for nematodes, enchytraeids and microarthropods 0.5, 2 and 8 km from the smelter. Special attention has been paid to the changes in the collembolan fauna. The sampling sites have been located in homogeneous Scots pine ( Pinus sylvestris) forests with podsolic soil profiles. In addition, an experiment has been carried out in which intact soil cores have been transferred in mesh baskets between the sites 2 and 8 km from the smelter…

EPR and Multiple Electron Resonance Spectroscopic Indication ofpara-Nitration of Aminyl Radicals

1996

Effects of differently induced stretch loads on neuromuscular control in drop jump exercise

1996

The neuromuscular characteristics of the triceps surae and vastus lateralis muscles and interactions between the pre-activation of these muscles and the muscle output itself during ground contact were investigated during various types of stretch-shortening cycle muscle loading. The loading of the muscles was effected by using three different types of drop jump exercise. These jumps allowed separate modifications of the loading of the leg extensor muscles by changing the velocity of the centre of gravity (CG) or by changing directly the body mass, which was also affected by changing artificially the acceleration of the CG. It was found that the eccentric peak angular velocity of the ankle jo…

Optimizing auditory images and distance metrics for self‐organizing timbre maps*

1996

Abstract The effect of using different auditory images and distance metrics on the final configuration of a self‐organized timbre map is examined by comparing distance matrices, obtained from simulations, with a similarity rating matrix, obtained using the same set of stimuli as in the simulations. Gradient images, which are intended to represent idealizations of physiological gradient maps in the auditory pathway, are constructed. The optimal auditory image and distance metric, with respect to the similarity rating data, are searched using the gradient method.

Synthesis and biological activity of novel sialyl-lewisX conjugates

1996

Abstract Novel sialyl Lewis X conjugates have been synthesized and evaluated as inhibitors of E- and P-selectin mediated cell adhesion in cell culture assays. The most potent conjugate in the static inhibition assays exhibited a significant and dose-dependent pharmacological potency as inhibitor of the edotoxin-induced leukocyte adhesion to the endothelium of postcapillary venules in rats.

Evolution of fitness in experimental populations of vesicular stomatitis virus

1996

Abstract The evolution of fitness in experimental clonal populations of vesicular stomatitis virus (VSV) has been compared under different genetic (fitness of initial clone) and demographic (population dynamics) regimes. In spite of the high genetic heterogeneity among replicates within experiments, there is a clear effect of population dynamics on the evolution of fitness. Those populations that went through strong periodic bottlenecks showed a decreased fitness in competition experiments with wild type. Conversely, mutant populations that were transferred under the dynamics of continuous population expansions increased their fitness when compared with the same wild type. The magnitude of …

Effect of Nitrogen Methylation on Cation and Anion Coordination by Hexa- and Heptaazamacrocycles. Catalytic Properties of These Ligands in ATP Dephos…

1996

The stability constants of the complexes formed by 1,10-dimethyl-1,4,7,10,13,16-hexaazacyclooctadecane (L) and 1,4,7-trimethyl-1,4,7,10,13,16,19-heptaazacyclohenicosane (L1) with Ni(2+), Cu(2+), Zn(2+), Cd(2+), and Pb(2+), as well as that for the formation of PbL2(2+) (L2 = 1,4,7,13-tetramethyl-1,4,7,10,13,16-hexaazacyclooctadecane), were determined by means of potentiometric (pH-metric) titrations in 0.15 mol dm(-)(3) NaClO(4) at 298.1 +/- 0.1 K. The enthalpy changes for the formation of Cu(2+) complexes with L and L1 were measured by means of microcalorimetry. These thermodynamic data were compared with those previously reported for L2, 1,4,7,10,13,16-hexaazacyclooctadecane (L3), and 1,4,…

Analyse sensorielle. Aspects méthodologiques dans le cas des fromages

1996

International audience

Variation in levels of aroma compounds of goat cheeses during ripening

1996

National audience

Effect of the association of surface flora on the sensory properties of mold ripened cheese

1996

International audience

Study of water-soluble fraction of goat cheeses

1996

National audience

Single W-boson production in e-\gamma colliders

1996

Single $W$-boson production in $e^-\gamma$ collisions with polarized beams is investigated. In the framework of the Standard Model the updated estimates for the measurement precision of photon anomalous coupling parameters $ \kappa_{ \gamma},$ $ \lambda_{ \gamma}$ at the Next Linear Collider with $ \sqrt{s_{ e\gamma }}=420$ GeV are obtained. The production of right-handed gauge bosons $ W^-_{ 2 }$ in this collision mode is also analysed. If the associated neutrino is light, the channel would give the best discovery reach for $ W^-_{ 2 }$ in the Next Linear Collider.

Asp333, Asp495, and His52.3 Form the Catalytic Triad of Rat Soluble Epoxide Hydrolase

1996

On the basis of the sequence similarity between mammalian epoxide hydrolases and bacterial haloalkane dehalogenase reported earlier (Arand, M., Grant, D. F., Beetham, J. K., Friedberg, T., Oesch, F., and Hammock, B. D. (1994) FEBS Lett. 338, 251-256; Beetham, J. K., Grant, D., Arand, M., Garbarino, J., Kiyosue, T., Pinot, F., Oesch, F., Belknap, W. R., Shinozaki, K., and hammock, B. D. (1995) DNA Cell. Biol. 14, 61-71) we selected candidate amino acid residues for the putative catalytic triad of the rat soluble epoxide hydrolase. The predicted amino acid residues were exchanged by site-directed mutagenesis of the epoxide hydrolase cDNA, followed by the expression of the respective mutant en…

Neutrino properties

1996

A brief sketch is made of the present observational status of neutrino properties, with emphasis on the hints from solar and atmospheric neutrinos, as well as cosmological data on the amplitude of primordial density fluctuations. Implications of neutrino mass in particle accelerators, astrophysics and cosmology are discussed.

Magnetic-field-enhanced outgoing excitonic resonance in multi-phonon Raman scattering from polar semiconductors

1996

A combined scattering mechanism involving the states of free electron-hole pairs (exciton continuum) and discrete excitons as intermediate states in the multi-phonon Raman scattering leads to (1) a strong increase of the scattering efficiency in the presence of a high magnetic field and to (2) an outgoing excitonic resonance: the two features are not compatible when only free pairs (leading to a strong increase of the scattering efficiency under the applied magnetic field) or discrete excitons (resulting in the outgoing resonance at the excitonic gap) are taken into account.

Faraday effect in standard optical fibers: dispersion of the effective Verdet constant

1996

We have measured the Faraday effect in silica standard optical fibers in the wavelength range 458-1523 nm. An effective Verdet constant Vef that exhibits a linear dependence on the square of the optical frequency ν is defined: V(ef) = (0.142 ± 0.004) × 10(-28) ν(2) rad T(-1) m(-1). We demonstrate that the negative effects of a small linear birefringence can be minimized by adjustment of the input polarization to an optimum state.

New hydrogel matrices based on chemical crosslinked α,β -polyas parthydrazide: Synthesis, characterization and in vivo biocompatibility studies

1996

New swellable micromatrices of α,β-polyasparthydrazide (PAHy) crosslinked with glutaraldehyde were prepared. The effect of crosslinking agent concentration was evaluated. In particular, crosslinking density affected aqueous dynamic swelling and glass-transition temperature of the material. The structure of prepared networks was also studied by scanning electron microscopy and X-ray analysis. Finally, biocompatibility of PAHy derivatives was investigated in vivo by subcutaneous implantation and in oral administration to laboratory animals.

Specific Protein Docking to Chelator Lipid Monolayers Monitored by FT-IR Spectroscopy at the Air–Water Interface

1996

Multiple Sialyl Lewisx N-Glycopeptides: Effective Ligands for E-Selectin

1996

Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of …

1996

Ca2+ stimulates exocytosis in permeabilized insulin-secreting cells. To investigate the putative cytosolic components involved in the Ca2+ response, HIT-T15 cells (a pancreatic B-cell line) were permeabilized with streptolysin-O, a procedure that allows rapid exchange of soluble components including macromolecules. We found that in this cell preparation the secretory response to Ca2+ but not to guanosine 5'-[gamma-thio]triphosphate was lost as a function of time and could be restored by rat brain cytosol in a concentration-dependent manner. Reconstitutive activity of rat brain cytosol was found in a high-molecular-mass heat-labile partially N-ethylmaleimide(NEM)-sensitive fraction. The NEM-…

Expression of Active Streptolysin O in Escherichia coli as a Maltose-Binding-Protein-Streptolysin-O Fusion Protein. The N-Terminal 70 Amino Acids are…

1996

Streptolysin 0 (SLO) is the prototype of a family of cytolysins that consists of proteins which bind to cholesterol and form very large transmembrane pores. Structure/function studies on the pore-forming cytolysin SLO have been complicated by the proteolytic inactivation of a substantial portion of recombinant SLO (rSLO) expressed in Escherichia coli. To overcome this problem, translational fusions between the E. coli maltose-binding protein (MBP) gene and SLO were constructed, using the vectors pMAL-p2 and pMAL-c2. MBP-SLO fusion proteins were degraded if secreted into the E. coli periplasm, but intact, soluble MBP-SLO fusion proteins were produced at high levels in the cytoplasm. Active S…

Role of excitons in double Raman resonances in GaAs quantum wells

1996

Raman scattering by longitudinal-optical phonons has been measured in GaAs-AlAs multiple quantum wells at high magnetic fields. Doubly resonant scattering processes are observed at photon energies corresponding to magneto-excitons with different principal quantum numbers for the incoming and outgoing channels. The existence of these initially forbidden scattering processes, their resonance energies, and their relative intensities are correctly reproduced by our theoretical description. The model takes into account the excitonic nature of the intermediate states, as well as scattering processes involving a nonzero in-plane phonon wave vector, which is required to allow inter-Landau level sca…

Gauge-independent approach to resonant transition amplitudes

1996

We present a new gauge-independent approach to resonant transition amplitudes with nonconserved external currents, based on the pinch technique method. In the context of $2\to 2$ and $2\to 3$ scattering processes, we show explicitly that the analytic results derived respect $U(1)_{em}$ gauge symmetry and do not depend on the choice of the $SU(2)_L$ gauge fixing. Our analytic approach treats, on equal footing, fermionic as well as bosonic contributions to the resummed gauge boson propagators, does not contain any residual space-like threshold terms, shows the correct high-energy unitarity behaviour, admits renormalization, and satisfies a number of other required properties, including the op…