TALISMAN: Eine Softwareumgebung für die interaktive Verarbeitung medizinischer Bildserien

Fur die kardiologische Diagnostik eroffnen sich durch die interaktive Auswertung digitalisierter Bildserien zahlreiche neue Moglichkeiten. Die entstehenden Hardware- und Softwaresystem sind interaktiv zu erproben und unterliegen einer schnellen Entwicklung und Veranderung der Algorithmen und der Benutzeroberflachen. Die TALISMAN- Softwareumgebung erleichtert diese Vorgange durch folgende Eigenschaften: 1. Unterstutzung eines modularen Aufbaus der Anwendungsprogramme durch Bereitstellung eines Botschaftensystems (vgl. objektorientierte Umgebungen wie z. B. Smalltalk). 2. Standardisierung der Struktur der bildverarbeitenden Programm-Module (z.B. Daten-struktur und visuelle Darstellung der Bot…

Parametric assessment of myocardial perfusion by densitometric evaluation of digital subtraction coronary angiograms: a comparison with tomographic TL-201 scintigraphy results

Densitometric results about local myocardial perfusion are compared with those derived from a quantitative analysis of TL-201 single photon emission computer tomograms (TL-201 SPECT). Ten patients underwent conventional TL-201 SPECT at rest and after maximum bicycle stress and dipyridamole infusion the day prior to the investigation. SPECT was applied to provide improved spatial resolution for the detection of perfusion abnormalities. During the catheterization procedure four digital subtraction coronary angiograms were performed, two of the left and two of the right coronary artery both before and after pharmacologically induced hyperemia by intracoronary papaverine. The densitometric para…

Measurement of the W→τντ cross section in pp collisions at s=7 TeV with the ATLAS experiment

The cross section for the production of W bosons with subsequent decay W to tau nu is measured with the ATLAS detector at the LHC. The analysis is based on a data sample that was recorded in 2010 at a proton-proton center-of-mass energy of sqrt(s) = 7 TeV and corresponds to an integrated luminosity of 34 pb^-1. The cross section is measured in a region of high detector acceptance and then extrapolated to the full phase space. The product of the total W production cross section and the W to tau nu branching ratio is measured to be 11.1 +/- 0.3 (stat) +/- 1.7 (syst) +/- 0.4 (lumi) nb.

Performance of jet substructure techniques for large-$R$ jets in proton-proton collisions at $\sqrt{s}$ = 7 TeV using the ATLAS detector

This paper presents the application of a variety of techniques to study jet substructure. The performance of various modified jet algorithms, or jet grooming techniques, for several jet types and event topologies is investigated for jets with transverse momentum larger than 300 GeV. Properties of jets subjected to the mass-drop filtering, trimming, and pruning algorithms are found to have a reduced sensitivity to multiple proton-proton interactions, are more stable at high luminosity and improve the physics potential of searches for heavy boosted objects. Studies of the expected discrimination power of jet mass and jet substructure observables in searches for new physics are also presented.…

Search for the pair production of scalar top quarks in the acoplanar charm jet final state in collisions at

A search for the pair production of scalar top quarks, {bar t}, has been performed in 360 pb{sup -1} of data from p{bar p} collisions at a center-of-mass energy of 1.96 TeV, collected by the D0 detector at the Fermilab Tevatron collider. The {bar t} decay mode considered is {bar t} {yields} c{bar {chi}}{sub 1}{sup 0}, where {bar {chi}}{sub 1}{sup 0} is the lightest supersymmetric particle. The topology analyzed therefore consists of a pair of acoplanar heavy-flavor jets with missing transverse energy. The data show good agreement with the standard model expectation, and a 95% C.L. exclusion domain in the (m{sub {tilde t}}, m{sub {tilde {chi}}{sub 1}{sup 0}}) plane has been determined, exten…

A microphysics guide to cirrus clouds - Part 1: Cirrus types

Abstract. The microphysical and radiative properties of cirrus clouds continue to be beyond understanding and thus still represent one of the largest uncertainties in the prediction of the Earth's climate (IPCC, 2013). Our study aims to provide a guide to cirrus microphysics, which is compiled from an extensive set of model simulations, covering the broad range of atmospheric conditions for cirrus formation and evolution. The model results are portrayed in the same parameter space as field measurements, i.e., in the Ice Water Content-Temperature (IWC-T) parameter space. We validate this cirrus analysis approach by evaluating cirrus data sets from 17 aircraft campaigns, conducted in the last…

Importance of calibration for diameter and area determination by intravascular ultrasound

Intravascular ultrasound (IVUS) permits quantitative assessment of the lumen diameter and area of coronary arteries. The experimental study was performed to evaluate the accuracy of diameter and area measurements.Lumen quantitation (lumen diameter D and cross-sectional area A) in lucite tubes (lumen diameter 2.5 to 5.7 mm, Plexiglas) was performed using a mechanical IVUS system (HP console, 3.5 F catheter, Boston Scientific, 30 MHz). The influence of fluid type (blood, water and saline solution), fluid temperature (20 degrees C/37 degrees C), catheter to catheter variation, gain setting and ultrasound frequency (12, 20 and 30 MHz) was determined. In blood at 20 degrees C there was a constan…

Acute dialysis: PMN-elastase as a new parameter for controlling individual anticoagulation with low molecular weight heparin (Fragmin).

Despite the improvements in the development of dialyzer membranes with greater hemocompatibility, an activation of the coagulation system occurs when blood comes into contact with exogenous surfaces. The large number of heparin dosage regimens demonstrate the difficulty to adapt general therapeutic guidelines. Low molecular weight heparin (Fragmin®) was administered as a single bolus dose for anticoagulation during 58 acute dialyses. Anti-Xa-activity, the plasma levels of the lysosomal elastase of the polymorphnuclear granulocytes (“PMN-elastase”) and of the thrombin-antithrombin III-complex (TAT) were measured at hourly intervals. Therapeutic anti-Xa-levels did not show evidence of suffici…

Verlustbehaftete Bilddatenreduktion von digitalen Koronarangiogrammen: Vergleich der Bildqualität durch einen objektiven Paramter

Search for light top squark pair production in final states with leptons and b-jets with the ATLAS detector in s=7 TeV proton–proton collisions

The results of a search for pair production of light top squarks are presented, using 4.7 fb(-1) of root s = 7 TeV proton-proton collisions collected with the ATLAS detector at the Large Hadron Collider. This search targets top squarks with masses similar to, or lighter than, the top quark mass. Final states containing exclusively one or two leptons (e, mu), large missing transverse momentum, light-flavour jets and b-jets are used to reconstruct the top squark pair system. Event-based mass scale variables are used to separate the signal from a large t (t) over bar background. No excess over the Standard Model expectations is found. The results are interpreted in the framework of the Minimal…

Measurement of the charge asymmetry in top quark pair production in pp collisions at root s=7 TeV using the ATLAS detector

A measurement of the top-antitop production charge asymmetry A[subscript C] is presented using data corresponding to an integrated luminosity of 1.04 fb[superscript −1] of pp collisions at s√=7 TeV collected by the ATLAS detector at the LHC. Events are selected with a single lepton (electron or muon), missing transverse momentum and at least four jets of which at least one jet is identified as coming from a b-quark. A kinematic fit is used to reconstruct the t[bar over t] event topology. After background subtraction, a Bayesian unfolding procedure is performed to correct for acceptance and detector effects. The measured value of A[subscript C] is A[subscript C]=−0.019±0.028 (stat.)±0.024 (s…

Assessment of image quality of intracoronary ultrasound systems with tissue-equivalent vessel phantoms

Imaging of vascular structures by intracoronary ultrasound (ICUS) is finding more and more applications in coronary diagnosis and in the assessment of interventional access. The authors describe a method for easy and quick production of tissue-equivalent vessel phantoms from a special hydrocolloid. The mechanical tolerance is less than 3/100 mm. With these phantoms the authors tested the calibration and measured the resolution properties of the SONOS intravascular ultrasonic system (Hewlett Packard). The measurements revealed a slight space related underestimation of diameters up to 280 /spl mu/m. Using cross correlation and auto correlation functions the authors analyzed digitized ultrason…

Measurement of the flavour composition of dijet events in pp collisions at √s = 7 TeV with the ATLAS detector

This paper describes a measurement of the flavour composition of dijet events produced in pp collisions at s√=7~TeVs=7~TeV using the ATLAS detector. The measurement uses the full 2010 data sample, corresponding to an integrated luminosity of 39 pb−1. Six possible combinations of light, charm and bottom jets are identified in the dijet events, where the jet flavour is defined by the presence of bottom, charm or solely light flavour hadrons in the jet. Kinematic variables, based on the properties of displaced decay vertices and optimised for jet flavour identification, are used in a multidimensional template fit to measure the fractions of these dijet flavour states as functions of the leadin…

Measurement of the differential cross-sections of inclusive, prompt and non-prompt J/ψ production in proton–proton collisions at s=7 TeV

The inclusive J/psi production cross-section and fraction of J/psi mesons produced in B-hadron decays are measured in proton proton collisions at root s = 7 TeV with the ATLAS detector at the LHC, as a function of the transverse momentum and rapidity of the J/psi, using 2.3 pb(-1) of integrated luminosity. The cross-section is measured from a minimum P-T of 1 GeV to a maximum of 70 GeV and for rapidities within vertical bar y vertical bar < 2.4 giving the widest reach of any measurement of J/psi production to date. The differential production cross-sections of prompt and non-prompt J/psi are separately determined and are compared to Colour Singlet NNLO*, Colour Evaporation Model, and FONLL …

Search for a Standard Model Higgs boson in the mass range 200–600 GeV in the H→ZZ→ℓ+ℓ−qq¯ decay channel with the ATLAS detector

A search for a heavy Standard Model Higgs boson decaying via H -> ZZ -> l(+)l(-)q (q) over bar, where l = e or mu, is presented. The search uses a data set of pp collisions at root s = 7 TeV, ...

Measurement of the top quark pair production cross-section with ATLAS in the single lepton channel

A measurement of the production cross-section for top quark pairs (t[bar over t]) in pp collisions at √s = 7 TeV is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in the single lepton topology by requiring an electron or muon, large missing transverse momentum and at least three jets. With a data sample of 35 pb[superscript −1], two different multivariate methods, one of which uses b-quark jet identification while the other does not, use kinematic variables to obtain cross-section measurements of σ[subscript t bar over t] = 187 ± 11 (stat.) [+18 over −17] (syst.) ± 6 (lumi.) pb and σ[subscript t bar over t] = 173 ± 17 (stat.) [+18 ove…

Search for the Xb and other hidden-beauty states in the π+π−ϒ(1S) channel at ATLAS

This Letter presents a search for a hidden-beauty counterpart of the X(3872) in the mass ranges 10.05--10.31 GeV and 10.40--11.00 GeV, in the channel Xb→π+π−Υ(1S)(→μ+μ−), using 16.2 fb−1 of s√=8 TeV pp collision data collected by the ATLAS detector at the LHC. No evidence for new narrow states is found, and upper limits are set on the product of the Xb cross section and branching fraction, relative to those of the Υ(2S), at the 95% confidence level using the CLS approach. These limits range from 0.8% to 4.0%, depending on mass. For masses above 10.1 GeV, the expected upper limits from this analysis are the most restrictive to date. Searches for production of the Υ(13DJ), Υ(10860), and Υ(110…

A search for flavour changing neutral currents in top-quark decays in pp collision data collected with the ATLAS detector at root s=7 TeV

A search for flavour changing neutral current (FCNC) processes in top-quark decays by the ATLAS Collaboration is presented. Data collected from pp collisions at the LHC at a centre-of-mass energy of √s = 7 TeV during 2011, corresponding to an integrated luminosity of 2.1 fb[superscript −1], were used. A search was performed for top-quark pair-production events, with one top quark decaying through the t → Zq FCNC (q = u, c) channel, and the other through the Standard Model dominant mode t → W b. Only the decays of the Z boson to charged leptons and leptonic W -boson decays were considered as signal. Consequently, the final-state topology is characterised by the presence of three isolated cha…

Search for a fermiophobic Higgs boson in the diphoton decay channel with the ATLAS detector

[Excerpt] A search for a fermiophobic Higgs boson using diphoton events produced in proton-proton collisions at a centre-of-mass energy of s√=7 TeV is performed using data corresponding to an integrated luminosity of 4.9 fb−1 collected by the ATLAS experiment at the Large Hadron Collider. A specific benchmark model is considered where all the fermion couplings to the Higgs boson are set to zero and the bosonic couplings are kept at the Standard Model values (fermiophobic Higgs model). The largest excess with respect to the background-only hypothesis is found at 125.5 GeV, with a local significance of 2.9 standard deviations, which reduces to 1.6 standard deviations when taking into account …

Aktuelle Komplikationsrate der perkutanen transluminalen Koronarangioplastie bei stabiler und unstabiler Angina

During a four-year period (1983-1986) percutaneous transluminal coronary angioplasty (PTCA) was performed on 930 patients with stable or unstable angina with a mortality rate of 0.4%. A transmural myocardial infarct developed in 1.1% and 1.0% of patients required an urgent aorto-coronary bypass. Thus the total rate of severe cardiac complications was 2.5%. Compared with the years 1983-1985, there was in 1986 a significant fall in the number of deaths and of myocardial infarcts from 2.2% to 0.5% (P less than 0.05), while there was a nonsignificant increase in emergency coronary bypass surgery from 0.7 to 1.3%. Patients with unstable angina compared with those with stable angina had a signifi…

Measurement of exclusive γγ→ℓ+ℓ− production in proton–proton collisions at s=7 TeV with the ATLAS detector

This Letter reports a measurement of the exclusive gamma gamma -> l(+)l(-) (l = e, mu) cross-section in proton-proton collisions at a centre-of-mass energy of 7 TeV by the ATLAS experiment at the LHC, based on an integrated luminosity of 4.6 fb(-1). For the electron or muon pairs satisfying exclusive selection criteria, a fit to the dilepton acoplanarity distribution is used to extract the fiducial cross-sections. The cross-section in the electron channel is determined to be sigma(excl)(gamma gamma -> e+e-) = 0.428 +/- 0.035 (stat.) +/- 0.018 (syst.) pbfor a phase-space region with invariant mass of the electron pairs greater than 24GeV, in which both electrons have transverse momentum p(T)…

Measurement of the top quark mass in the dilepton channel

We present a measurement of the top quark mass in the dilepton channel based on approximately 370/pb of data collected by the D0 experiment during Run II of the Fermilab Tevatron collider. We employ two different methods to extract the top quark mass. We show that both methods yield consistent results using ensemble tests of events generated with the D0 Monte Carlo simulation. We combine the results from the two methods to obtain a top quark mass m_t = 178.1 +/- 8.2 GeV. The statistical uncertainty is 6.7 GeV and the systematic uncertainty is 4.8 GeV.

Reversibilität von Veränderungen der links- und rechtsventrikulären Geometrie und Hämodynamik bei pulmonaler Hypertonie. Echokardiographische Charakterisierung bei Patienten vor und nach pulmonaler Thrombendarteriektomie (Reversibility of changes in left- and right ventricular geometry and hemodynamics in patients with pulmonary hypertension. Echocardiographic characteristics before and after pulmonary thrombendarterectomy)

Durch pulmonale Thrombendarteriektomie kann bei Patienten mit chronischer embolisch bedingter pulmonaler Hypertonie eine akute rechtsventrikulare Nachlastsenkung erzielt werden. Der Einflus auf die rechts- und linksventrikulare Geometrie und Hamodynamik wurde prospektiv mit Hilfe der transthorakalen Echokardiographie an einem Kollektiv von 14 Patienten (8 Frauen, 6 Manner; Alter 55 ± 20 Jahre) vor und nach 18 ± 12 Tagen postoperativ untersucht. Nach operativer Desobliteration der Pulmonalarterien fand sich eine Abnahme des invasiv bestimmten totalen pulmonalen Gefaswiderstands von 986 ± 318 auf 323 ± 280 dyn x s/cm5; p < 0,05. Der echokardiographisch erfaste systolische pulmonalarterielle D…

Quantitative comparison of new image processing methods for volumetric analysis of left ventricular contrast echocardiograms

An effort has been made to develop image processing methods which allow a definite and precise tracking of the borderline of the ventricle in two-dimensional echocardiograms. Experience is reported with two new methods, which are based on the gray-level rise (GL) and the signal-to-noise ratio (SNR) in combined heart-phase-triggered image series. A quantitative comparison of these time-series methods is presented with respect to the interpretation of a single native image (noncontrast image), a single contrast-material image, the corresponding subtraction image, and the corresponding color superposition image. The comparison is based on the calculation of the ejection fraction using the abov…

The ATLAS Data Acquisition and High Level Trigger system

Journal of Instrumentation 11(06), P06008 (2016). doi:10.1088/1748-0221/11/06/P06008

Measurement of the cross-section for b-jets produced in association with a Z boson at s=7 TeV with the ATLAS detector

A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons, and at least one b-jet, identified by its displaced vertex, with transverse momentum p(T) > 25 GeV and rapidity vertical bar y vertical bar < 2.1. After subtraction of background processes, the yield is extracted from the vertex mass distribution of the candidate b-jets. The ratio of this cross-se…

Measurement of the transverse momentum distribution of Z/γ⁎ bosons in proton–proton collisions at s=7 TeV with the ATLAS detector

A measurement of the Z/gamma* transverse momentum (p(T)(Z)) distribution in proton-proton collisions at root s = 7 TeV is presented using Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) decay ...

The ATLAS Simulation Infrastructure

52 páginas, 10 figuras, 18 tablas.-- This article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al. (The ATLAS Collaboration).

Jet mass and substructure of inclusive jets in $ \sqrt {s} = 7\;{\text{TeV}} $ pp collisions with the ATLAS experiment

Recent studies have highlighted the potential of jet substructure techniques to identify the hadronic decays of boosted heavy particles. These studies all rely upon the assumption that the internal substructure of jets generated by QCD radiation is well understood. In this article, this assumption is tested on an inclusive sample of jets recorded with the ATLAS detector in 2010, which corresponds to 35 pb-1 of pp collisions delivered by the LHC at √s = 7TeV. In a subsample of events with single pp collisions, measurements corrected for detector efficiency and resolution are presented with full systematic uncertainties. Jet invariant mass, kt splitting scales and N-subjettiness variables are…

Paroxysmal atrial fibrillation and high degree AV block: use of single-lead VDDR pacing with mode switching.

Dual chamber rate responsive pacing incorporating a mode switching option is increasingly used in patients with chronic paroxysmal atrial fibrillation and high degree AV block. Single-lead VDDR pacemakers have rarely used for this indication. The purpose of this study was to determine their reliability of atrial sensing during atrial fibrillation, the percentage of atrial synchronous ventricular pacing, and the behavior of the sinus rate outside the phases of atrial fibrillation. We studied ten patients with a single-lead VDDR pacemaker implanted for this indication. Follow-up visits were performed at predischarge and after 1, 3, 6, 12, 18, and 24 months. During the mean follow-up period of…

Three dimensional reconstruction of intracoronary ultrasound images: roadmapping with simultaneously digitised coronary angiograms

Three dimensional reconstruction of intracoronary ultrasound images offers a better appreciation of the axial relationship of vessel features and permits volumetric assessment, both of which depend critically on the spatial accuracy of the technique. This in turn is dependent on precise longitudinal orientation of the transducer in the vessel. The authors have developed a system which utilises simultaneously digitised fluoroscopic tracking of the radio-opaque transducer to orient the corresponding 2D ICUS images. This system may offer improved spatial accuracy of the three dimensional reconstruction and a means of precise identification of the 2D ICUS image which corresponds with a selected…

Search for scalar leptoquarks in the acoplanar jet topology in pp¯ collisions at s=1.96 TeV

A search for leptoquarks has been performed in 310 pb{sup -1} of data from p{bar p} collisions at a center-of-mass energy of 1.96 TeV, collected by the D0 detector at the Fermilab Tevatron Collider. The topology analyzed consists of acoplanar jets with missing transverse energy. The data show good agreement with standard model expectations, and a lower mass limit of 136 GeV has been set at the 95% C.L. for a scalar leptoquark decaying exclusively into a quark and a neutrino.

A query language for medical statistical analysis

While standard query languages support primarily the definition of single queries, in the evaluation of medical studies one usually formulates large sets of interdependent queries. A set of this type is called an integrated transaction. Our system for the definition of integrated transactions is based on the observation that in medicine a large number of statistical evaluations is founded on a conceptional model that can be structured as a tree. We describe a screen oriented tree editor for the relational data base system DBase and report on our experience with its application in the evaluation of the success rate of PTCA interventions.

Farbkodierte Dopplerechokardiographie bei dilatativer Kardiomyopathie

Die dilatative Kardiomyopathie ist morphologisch durch die Dilatation, insbesondere des linken Ventrikels, und funktionell durch die eingeschrankte Ejek-tionsfraktion gekennzeichnet. Sowohl die Morphologie als auch die Ejektions-fraktion konnen mittels ein- und zweidimensionaler Echokardiographie nichtinvasiv beurteilt werden (Corya et al. 1974; Feigenbaum 1986). Durch die konventionellen Dopplerverfahren ist zusatzlich eine Erkennung und semiquantitative Schweregradabschatzung von begleitenden AV-Klappen-Insuffizienzen moglich (Abbasi et al. 1980; Keren et al. 1986). Ferner wurden Versuche einer Quantifizierung von Klappeninsuffizienzen unternommen sowie die systolische und diastolische Fu…

A study of the material in the ATLAS inner detector using secondary hadronic interactions

The ATLAS inner detector is used to reconstruct secondary vertices due to hadronic interactions of primary collision products, so probing the location and amount of material in the inner region of ATLAS. Data collected in 7 TeV pp collisions at the LHC, with a minimum bias trigger, are used for comparisons with simulated events. The reconstructed secondary vertices have spatial resolutions ranging from ~ 200μm to 1 mm. The overall material description in the simulation is validated to within an experimental uncertainty of about 7%. This will lead to a better understanding of the reconstruction of various objects such as tracks, leptons, jets, and missing transverse momentum.

Intensivtherapie des Myokardinfarktes — Limitierung der Infarktgröße

Der akute Myokardinfarkt gehort mit der instabilen Angina pectoris und dem plotzlichen Herztod zu den drei akuten Koronarsyndromen, die sich nur im Ausmas und der Geschwindigkeit der Thrombusentstehung unterscheiden [16]. Ein solcher Koronarverschlus (Abb. 1) fuhrt zu einem akuten Ausfall der Myokardperfusion und innerhalb weniger Sekunden zum Ausfall der Funktion des nicht mehr perfundierten Myokards. Wird das Gefas innerhalb weniger Minuten wieder geoffnet [34, 37, 38, 48], erholt sich das Myokard vollstandig. Bleibt die Durchblutung langere Zeit blockiert, entwickelt sich ein Infarkt, der von subendokardial nach epikardial sich ausbreitet [24, 46, 47, 52, 53]. t bedeutet eine kurze Ischa…

Measurement of the cross section for top-quark pair production in pp collisions at √s = 7TeV with the ATLAS detector using final states with two high-p(T) leptons

A measurement is reported of the production cross section of top-quark pairs (tt¯) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the LHC. Candidate events have a signature consistent with containing two isolated leptons, large missing transverse momentum, and at least two jets. Using a data sample corresponding to an integrated luminosity of 0.70 fb−1, a tt¯ production cross section σtt¯=176±5(stat.)+14−11(syst.)±8(lum.) pb is measured for an assumed top-quark mass of mt = 172.5 GeV. This measurement is in good agreement with Standard Model predictions.

Evidence for the associated production of a W boson and a top quark in ATLAS at √s = 7 TeV

This Letter presents evidence for the associated production of a W boson and a top quark using 2.05 fb[superscript −1] of pp collision data at √s = 7 TeV accumulated with the ATLAS detector at the LHC. The analysis is based on the selection of the dileptonic final states with events featuring two isolated leptons, electron or muon, with significant transverse missing momentum and at least one jet. An approach based on boosted decision trees has been developed to improve the discrimination of single top-quark Wt events from background. A template fit to the final classifier distributions is performed to determine the cross-section. The result is incompatible with the background-only hypothes…

Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portu…

Search for new physics in the dijet mass distribution using 1 fb−1 of pp collision data at s=7 TeV collected by the ATLAS detector

Invariant mass distributions of jet pairs (dijets) produced in LHC proton-proton collisions at a centre-of-mass energy root s = 7 TeV have been studied using a data set corresponding to an integrat ...

Measurement of the cross section for the production of a W boson in association with b-jets in pp collisions at s=7 TeV with the ATLAS detector

A measurement is presented of the cross section for the production of a W boson with one or two jets, of which at least one must be a b-jet, in pp collisions at root s = 7 TeV. Production via top d ...

Flussquantifizierung in Koronar- und Bypass- gefäßen mit der MR-Phasenkontrasttechnik

Ziel: Es sollte die Genauigkeit der MR-Phasenkontrastmethode zur Ermittlung des Flusses in Koronararterien und koronaren Bypassgefasen bestimmt werden. Material und Methode: Die MRT-Flussmessungen von 12 Patienten mit 22 Bypassgefasen wurden mit intraoperativ mittels Ultraschalldurchflussmethode bestimmten Flussen verglichen. Praoperativ wurden zusatzlich Flussmessungen in 28 Koronararterien von 20 Patienten durchgefuhrt. Zur MRT-Flussmessung wurde eine segmentierte 2D-Flash-Sequenz verwendet, die eine zeitliche Auflosung von 110 bzw. 125 ms aufwies. Dies ermoglichte die Akquisition von 6–8 Bildpaaren pro Herzzyklus. Ergebnisse: Es bestand eine signifikante Korrelation zwischen den Ergebnis…

Time delays in starting thrombolytic therapy

Indications for early PTCA after thrombolysis

There are several ways to reopen an acutely occluded coronary artery. Thrombolysis can be achieved with various methods (1, 5, 7, 10). After thrombolysis we find that the residual thrombus can sometimes be seen, but in most cases, a more or less high grade coronary stenosis remains (2). It is also a question of whether it is always optimal to reopen the vessel, because if the vessel remains occluded, another occlusion cannot occur. With this situation one faces the possibility that the patient will suffer another infarction, and that the vessel will occlude again (4).

Arrhythmia profile in acromegaly.

In a controlled study, the cardiac involvement and arrhythmia profile of 32 patients with acromegaly were correlated with endocrine parameters (somatomedine C, growth hormone), clinical score and duration of the disease. Data were compared with those of 50 controls free of cardiac disease. Stress ECG, 24 h Holter monitoring and echocardiography were performed. Supraventricular premature complexes occurred no more often in acromegalics than in controls. Both prevalence and severity of ventricular arrhythmia, however, were significantly higher in patients compared to controls (P less than 0.01). 15/32 (48%) acromegalic patients had complex ventricular arrhythmias (Lown III-IV) as compared wit…

Search for Stopped Gluinos frompp¯Collisions ats=1.96  TeV

Long-lived, heavy particles are predicted in a number of models beyond the standard model of particle physics. We present the first direct search for such particles' decays, occurring up to 100 h after their production and not synchronized with an accelerator bunch crossing. We apply the analysis to the gluino (g), predicted in split supersymmetry, which after hadronization can become charged and lose enough momentum through ionization to come to rest in dense particle detectors. Approximately 410 pb(-1) of p (p) over bar collisions at root s = 1.96 TeV collected with the D0 detector during Run II of the Fermilab Tevatron collider are analyzed in search of such "stopped gluinos" decaying in…

Measurement of the top quark pair production cross section in pp collisions at s=7 TeV in dilepton final states with ATLAS

A measurement of the production cross section of top quark pairs (ttbar) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider is reported. Candidate events are selected in the dilepton topology with large missing transverse energy and at least two jets. Using a data sample corresponding to an integrated luminosity of 35 pb^-1, a ttbar production cross section of 171 +/- 20(stat.) +/- 14(syst.) +8-6(lum.) pb is measured for an assumed top quark mass of 172.5 GeV. A second measurement requiring at least one jet identified as coming from a b quark yields a comparable result, demonstrating that the dilepton final states ar…

The influence of Albunex on the pulmonary circulation in patients with pulmonary hypertension or left heart failure.

To determine the safety of the ultrasound contrast agent Albunex, its influence on right and left heart haemodynamics in patients with pulmonary artery hypertension or left heart failure was assessed after intravenous injection. Patients with a left ventricular ejection fraction smaller than 40% or a systolic pulmonary artery pressure greater than 40 mmHg received 0.08 and 0.22 ml.kg -1 Albunex and 10 ml albumin in random order during right heart catheterization and transthoracic echocardiography. Right atrial, systolic and diastolic pulmonary artery and capillary wedge pressures were measured at 3 min and 5 min and cardiac output at 5 min after the intravenous injection of Albunex and cont…

Observation and Properties of the Orbitally ExcitedBs2*Meson

We report the direct observation of the excited L=1 state B_{s2}* in fully reconstructed decays to B+K-. The mass of the B_{s2}* meson is measured to be {5839.6 +- 1.1 (stat.) +- 0.7 (syst.) MeV/c^2, and its production rate relative to the B+ meson is measured to be [1.15 +- 0.23 (stat.) +- 0.13 (syst.)] %.

Search for the Standard Model Higgs boson in the decay channel H→ZZ(⁎)→4ℓ with the ATLAS detector

A search for the Standard Model Higgs boson in the decay channel H -> ZZ(()*()) l(+)l(-)l'l'(-), where l = e, mu, is presented. Proton-proton collision data at root s = 7 TeV recorded with the A ...

Characterisation and mitigation of beam-induced backgrounds observed in the ATLAS detector during the 2011 proton-proton run

This paper presents a summary of beam-induced backgrounds observed in the ATLAS detector and discusses methods to tag and remove background contaminated events in data. Triggerrate based monitoring of beam-related backgrounds is presented. The correlations of backgrounds with machine conditions, such as residual pressure in the beam-pipe, are discussed. Results from dedicated beam-background simulations are shown, and their qualitative agreement with data is evaluated. Data taken during the passage of unpaired, i.e. non-colliding, proton bunches is used to obtain background-enriched data samples. These are used to identify characteristic features of beam-induced backgrounds, which then are …

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb[superscript −1] collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutral…

Measurement of theΛbLifetime in the Exclusive DecayΛb→J/ψΛ

We have measured the {lambda}{sub b} lifetime using the exclusive decay {lambda}{sub b}{yields}J/{psi}{lambda}, based on 1.2 fb{sup -1} of data collected with the D0 detector during 2002-2006. From 171 reconstructed {lambda}{sub b} decays, where the J/{psi} and {lambda} are identified via the decays J/{psi}{yields}{mu}{sup +}{mu}{sup -} and {lambda}{yields}p{pi}, we measured the {lambda}{sub b} lifetime to be {tau}({lambda}{sub b})=1.218{sub -0.115}{sup +0.130}(stat){+-}0.042(syst) ps. We also measured the B{sup 0} lifetime in the decay B{sup 0}{yields}J/{psi}({mu}{sup +}{mu}{sup -})K{sub S}{sup 0}({pi}{sup +}{pi}{sup -}) to be {tau}(B{sup 0})=1.501{sub -0.074}{sup +0.078}(stat){+-}0.050(sy…

Myokardperfusion und -funktion nach Koronarinterventionen

Ein bei Belastung zunehmender Sauerstoffbedarf des Myokards kann im wesentlichen nur durch eine Steigerung der Koronardurchblutung gedeckt werden. Dies geschieht zu ca. 90% durch Dilatation der arteriolaren Widerstandsgefase und nur zu ca. 10% durch Dilatation der epikardialen Koronargefase, die angiographisch sichtbar gemacht werden konnen. Die Differenz zwischen Ruhe- und maximal moglichem Blutflus wird als Koronarreserve bezeichnet. Die Messung des koronaren Blutflusses, der Perfusion, des myokardialen Stoffwechsels sowie der Auswirkung auf die Myokardfunktion erfolgt durch verschiedenste Verfahren: Thallium-Szintigraphie, Positionen-Emissions-Tomographie, Magnetresonanztomographie, Clea…

Measurement of the t-channel single top-quark production cross section in pp collisions at s=7 TeV with the ATLAS detector

We report a measurement of the cross section of single top-quark production in the t-channel using 1.04 fb -1 of pp collision data at s=7 TeV recorded with the ATLAS detector at the LHC. Selected e ...

Das Mitralklappenprolaps-Syndrom

Measurement of the azimuthal ordering of charged hadrons with the ATLAS detector

This paper presents a study of the possible ordering of charged hadrons in the azimuthal angle relative to the beam axis in high-energy proton-proton collisions at the Large Hadron Collider (LHC). A spectral analysis of correlations between longitudinal and transverse components of the momentum of the charged hadrons, driven by the search for phenomena related to the structure of the QCD field, is performed. Data were recorded with the ATLAS detector at center-of-mass energies of √s=900  GeV and √s=7  TeV. The correlations measured in a kinematic region dominated by low-pT particles are not well described by conventional models of hadron production. The measured spectra show features consis…

Aktuelle Therapie der koronaren Herzkrankheit

In der vorliegenden Arbeit wird der gegenwartige Stand der Pravention und der medikamentosen Behandlung der koronaren Herzkrankheit aufgezeigt. Auf vielen verschiedenen Feldern konnten Erfolge erzielt und fruhere Ergebnisse durch experimentelle Forschung oder klinische Studien gesichert werden. Das gilt besonders fur den Einsatz von Azetylsalizylsaure zur Sekundarprophylaxe koronarer Ereignisse und kombiniert mit Fibrinolytika beim akuten Myokardinfarkt sowie kombiniert mit niedermolekularem Heparin beim akuten Koronarsyndrom. Direkte Thrombinantagonisten, Glykoprotein-Rezeptorantagonisten, Ticlopidin sowie neue und weiterentwickelte Fibrinolytika erbrachten grose Fortschritte. Der molekula…

Factors Correlating with Restenosis after PTCA

Since its introduction in 1977 [7, 8], PTCA has been widely used in patients with coronary artery disease. Restenosis with recurrence of angina remains the major problem, limiting the long-term success after PTCA. Reported restenosis rates vary from 17% to 47% [9–19, 22–26]. In larger series [12, 15, 26] a restenosis rate of about 30% was constantly found, irrespective of the definition of restenosis in use.

Two-body contributions to the effective mass in nuclear effective interactions

Starting from general expressions of well-chosen symmetric nuclear matter quantities derived for both zero- and finite-range effective theories, we derive the contributions to the effective mass. We first show that, independently of the range, the two-body contribution is enough to describe correctly the saturation mechanism but gives an effective mass value around $m^*/m \simeq 0.4$. Then, we show that the full interaction (by instance, an effective two-body density-dependent term on top of the pure two-body term) is needed to reach the accepted value $m^*/m \simeq 0.7-0.8$.

Recombinant hirudin as a periprocedural antithrombotic in coronary angioplasty for unstable angina pectoris

Percutaneous transluminal coronary angioplasty is often complicated by thrombotic abrupt vessel closure in patients with unstable angina pectoris. The present multicentre trial was performed to determine the feasibility of two-dose regimens of recombinant hirudin (r-hirudin) compared to standard heparin in patients undergoing coronary angioplasty for unstable angina, and to investigate the effects of the different treatment regimen on markers of coagulation activation. At five participating centres, 61 patients were randomly enrolled in one of two sequential groups of r-hirudin (group 1: 0.3 mg.kg-1 i.v. bolus, 0.12 mg.kg-1.h-1 i.v. infusion; 21 patients; group 2: 0.5 mg.kg-1 i.v. bolus, 0.…

Verlaufsbeobachtung von Patienten mit chronischer Aortenklappeninsuffizienz unter ACE-Hemmer-Therapie (Follow-up of patients with chronic severe aortic regurgitation)

In dieser Untersuchung wurde der Einflus einer 3monatigen ACE-Hemmer-Therapie mit Cilazapril (2,5–5 mg) bei 13 Patienten mit chronischer Aortenklappeninsuffizienz spiroergometrisch und echokardiographisch untersucht. Nach 3monatiger Therapie sanken der linksventrikulare enddiastolische Diameter-Index von 3,5 auf 3,1 cm/m2 (p = 0,005), der linksventrikulare endsystolische Diameter-Index von 2,3 auf 2,0 cm/m2 (p = 0,005). Der Wallstress reduzierte sich von 174 auf 150 dyn/cm2 (p = 0,01). Die linksventrikulare Muskelmasse nahm um 14% ab, von anfangs 570 g (= 295 g/m2) auf 488 g (= 253 g/m2) (p < 0,05). Die von apikal gemesesene Jetflache reduzierte sich von 10,1 auf 8,1 cm2 (p < 0,05). Weder d…

Elektrokardiographische Infarktlokalisation: Ein Beitrag zur EKG-Nomenklatur

Search for diphoton events with large missing transverse momentum in 1 fb−1 of 7 TeV proton–proton collision data with the ATLAS detector

A search for diphoton events with large missing transverse momentum has been performed using 1.07 fb(-1) of proton-proton collision data at root s = 7 TeV recorded with the ATLAS detector. No excess of events was observed above the Standard Model prediction and 95% Confidence Level (CL) upper limits are set on the production cross section for new physics. The limits depend on each model parameter space and vary as follows: sigma < (22-129) fb in the context of a generalised model of gauge-mediated supersymmetry breaking (GGM) with a bino-like lightest neutralino, sigma < (27-91) fb in the context of a minimal model of gauge-mediated supersymmetry breaking (SPS8), and sigma < (15-27) fb in t…

Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC

19 páginas, 2 figuras, 1 tabla.-- et al.(ATLAS Collaboration).

Search for first generation scalar leptoquarks in pp collisions at s=7 TeV with the ATLAS detector

We report a search for first generation scalar leptoquarks using 1.03 fb(-1) of proton-proton collisions data produced by the Large Hadron Collider at root s = 7 TeV and recorded by the ATLAS experiment. Leptoquarks are sought via their decay into an electron or neutrino and a quark, producing events with two oppositely charged electrons and at least two jets, or events with an electron, missing transverse momentum and at least two jets. Control data samples are used to validate background predictions from Monte Carlo simulation. In the signal region, the observed event yields are consistent with the background expectations. We exclude at 95% confidence level the production of first generat…

Measurement of the differential cross section for the production of an isolated photon with associated jet in pp¯ collisions at s=1.96 TeV

The process ppbar -> photon + jet + X is studied using 1.0 fb^-1 of data collected by the D0 detector at the Fermilab Tevatron ppbar collider at a center-of-mass energy sqrt(s)=1.96 TeV. Photons are reconstructed in the central rapidity region |y_gamma|<1.0 with transverse momenta in the range 3015 GeV. The differential cross section d^3sigma/dPt_gamma dy_gamma dy_jet is measured as a function of Pt_gamma in four regions, differing by the relative orientations of the photon and the jet in rapidity. Ratios between the differential cross sections in each region are also presented. Next-to-leading order QCD predictions using different parameterizations of parton distribution functions and theo…

Measurement of inclusive two-particle angular correlations in pp collisions with the ATLAS detector at the LHC

We present a measurement of two-particle angular correlations in proton- proton collisions at s√=900 GeV and 7 TeV. The collision events were collected during 2009 and 2010 with the ATLAS detector at the Large Hadron Collider using a single-arm minimum bias trigger. Correlations are measured for charged particles produced in the kinematic range of transverse momentum pT > 100 MeV and pseudorapidity |η| < 2.5. A complex structure in pseudorapidity and azimuth is observed at both collision energies. Results are compared to pythia 8 and herwig++ as well as to the AMBT2B, DW and Perugia 2011 tunes of pythia 6. The data are not satisfactorily described by any of these models.

Combined aortic and mitral stenosis in mucopolysaccharidosis type I-S (Ullrich-Scheie syndrome)

The genetic mucopolysaccharidosis syndromes (MPS) are autosomal recessive inborn errors of metabolism. Heart valve involvement in MPS is not uncommon but only a few case reports of successful cardiac surgery are available. In particular, reports of combined aortic and mitral stenosis associated with MPS type I-S are very rare. Both type I and type VI MPS are associated with significant left sided valvar heart disease that requires surgical valve replacement because of irregular valve thickening, fibrosis, and calcification. A 35 year old man had severe mitral valve stenosis after successful surgical replacement of a stenotic aortic valve. Valvar heart disease was investigated by cardiac ult…

Measurement of angular correlations in Drell–Yan lepton pairs to probe Z/γ⁎ boson transverse momentum at s=7 TeV with the ATLAS detector

A measurement of angular correlations in Drell-Yan lepton pairs via the phi(eta)* observable is presented. This variable probes the same physics as the Z/gamma* boson transverse momentum with a better experimental resolution. The Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) decays produced in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV are used. The data were collected with the ATLAS detector at the LHC and correspond to an integrated luminosity of 4.6 fb(-1). Normalised differential cross sections as a function of phi(eta)* are measured separately for electron and muon decay channels. These channels are then combined for improved accuracy. The cross section is …

Search for scalar top quarks in the acoplanar charm jets and missing transverse energy final state in pp¯ collisions at s=1.96 TeV

We present a search for the pair production of scalar top quarks, $\tilde{t}$, using 995 pb$^{-1}$ of data collected in $p\bar{p}$ collisions with the D0 detector at the Fermilab Tevatron Collider at $\sqrt{s} = 1.96$ TeV. Both scalar top quarks are assumed to decay into a charm quark and a neutralino ($\tilde{\chi}^{0}_{1}$), where $\tilde{\chi}^{0}_{1}$ is the lightest supersymmetric particle. This leads to a final state with two acoplanar charm jets and missing transverse energy. We find the yield of such events to be consistent with the standard model expectation, and exclude sets of $\tilde{t}$ and $\tilde{\chi}^{0}_{1} $ masses at the 95% C.L. that substantially extend the domain excl…

Drift Time Measurement in the ATLAS Liquid Argon Electromagnetic Calorimeter using Cosmic Muons

The ionization signals in the liquid argon of the ATLAS electromagnetic calorimeter are studied in detail using cosmic muons. In particular, the drift time of the ionization electrons is measured and used to assess the intrinsic uniformity of the calorimeter gaps and estimate its impact on the constant term of the energy resolution. The drift times of electrons in the cells of the second layer of the calorimeter are uniform at the level of 1.3% in the barrel and 2.8% in the endcaps. This leads to an estimated contribution to the constant term of (0.29-0.04+0.05)% in the barrel and (0.54-0.04+0.06)% in the endcaps. The same data are used to measure the drift velocity of ionization electrons …

Measurement of the W boson polarization in top quark decays with the ATLAS detector

This paper presents measurements of the polarization of W bosons in top quark decays, derived from t¯t events with missing transverse momentum, one charged lepton and at least four jets, or two charged leptons and at least two jets. Data from pp collisions at a centre-of-mass energy of 7 TeV were collected with the ATLAS experiment at the LHC and correspond to an integrated luminosity of 1.04 fb−1. The measured fractions of longitudinally, left- and right-handed polarization are F0 = 0.67 ± 0.07, FL = 0.32 ± 0.04 and FR = 0.01 ± 0.05, in agreement with the Standard Model predictions. As the polarization of the W bosons in top quark decays is sensitive to the Wtb vertex Lorentz structure and…

Nachruf auf Prof. Dr. med. Sven Effert

Measurement of the jet fragmentation function and transverse profile in proton-proton collisions at a center-of-mass energy of 7 TeV with the ATLAS detector

The jet fragmentation function and transverse profile for jets with 25 GeV<pT jet<500 GeV and |ηjet|<1.2 produced in proton–proton collisions with a center-of-mass energy of 7 TeV are presented. The measurement is performed using data with an integrated luminosity of 36 pb−1. Jets are reconstructed and their momentum measured using calorimetric information. The momenta of the charged particle constituents are measured using the tracking system. The distributions corrected for detector effects are compared with various Monte Carlo event generators and generator tunes. Several of these choices show good agreement with the measured fragmentation function. None of these choices reproduce both t…

Search for heavy neutrinos and right-handed W bosons in events with two leptons and jets in pp collisions at √s=7 TeV with the ATLAS detector

This letter reports on a search for hypothetical heavy neutrinos, N, and right-handed gauge bosons, WR, in events with high transverse momentum objects which include two reconstructed leptons and at least one hadronic jet. The results were obtained from data corresponding to an integrated luminosity of 2.1 fb−1 collected in proton–proton collisions at √s=7 TeV with the ATLAS detector at the CERN Large Hadron Collider. No excess above the Standard Model background expectation is observed. Excluded mass regions for Majorana and Dirac neutrinos are presented using two approaches for interactions that violate lepton and lepton-flavor numbers. One approach uses an effective operator framework, t…

Searches for heavy long-lived sleptons and R-hadrons with the ATLAS detector in pp collisions at

A search for long-lived particles is performed using a data sample of 4.7 fb(-1) from proton-proton collisions at a centre-of-mass energy. root s = 7 TeV collected by the ATLAS detector at the LHC. No excess is observed above the estimated background and lower limits, at 95% confidence level, are set on the mass of the long-lived particles in different scenarios, based on their possible interactions in the inner detector, the calorimeters and the muon spectrometer. Long-lived staus in gauge-mediated SUSY-breaking models are excluded up to a mass of 300 GeV for tan beta = 5-20. Directly produced long-lived sleptons are excluded up to a mass of 278 GeV. R-hadrons, composites of gluino (stop, …

Linksventrikuläre Funktionsanalyse: Kritische Wertung der Stellung der Echokardiographie

Mit Hilfe der M-mode-Echokardiographie last sich das Myokard des linken Ventrikels mit Endo- und Epikard abgrenzen. Die zeitliche Auflosung der M-mode-Echokardiographie ubertrifft dabei alle anderen zur Verfugung stehenden Methoden. Aus den diastolischen und systolischen Werten wird die Verkurzungsfraktion und die Wanddickenanderung bestimmt. Liegt keine Wandbewegungsstorung vor, kann die globale Ventrikelfunktion uber die Durchmesserbestimmung (Abb. 1) sicher abgeschatzt werden [13]. Der enddiastolische Durchmesser wurde dabei zu Beginn von QRS, der endsystolische Durchmesser zum Zeitpunkt der Inzisur der Septumbewegung bestimmt [13]. Nur fur wenige Patienten konnte eine fehlerhafte Klassi…

Measurement of the top quark pair cross section with ATLAS in pp collisions at s=7 TeV using final states with an electron or a muon and a hadronically decaying τ lepton

Measurement of the top quark pair cross section with ATLAS in pp collisions at root s=7 TeV using final states with an electron or a muon and a hadronically decaying tau lepton

Effects of Ciprostene on Restenosis Rate during Therapeutic Transluminal Coronary Angioplasty

Ciprostene, a chemically stable prostacyclin analog was studied for its effects on restenosis in patients with coronary artery disease undergoing therapeutic percutaneous transluminal coronary angioplasty (PTCA). In a double-blind, randomized trial 32 patients were randomized to receive either ciprostene or the respective placebo. The infusion started intracoronarily at a rate of 40 ng/kg/min 20 min before introduction of the balloon catheter into the coronary artery. Thereafter infusion was continued intravenously for 36 hours at a rate of 120 ng/kg/min and a tapering off period until 48 hours. The quantitative analyses of the degree of coronary artery stenoses on the angiographic films be…

Requirements on resolution of digital imaging equipment in the cardiac catheterization laboratory.

We evaluated the requirements on spatial resolution of digital imaging equipment in the cardiac catheterization laboratory. Fifty cinefilms of the heart as the biological object and one film of a lead-ladder-pattern as an objective test were used. The patient films were examined for the visibility of the left ventricular angiogram, coronary arterial tree, coronary artery lesions, branching of septal arteries and the number of septal arteries. All films were viewed three times: with a 625 line TV-system, with a 1249 line TV-system and with a cineprojector. It was found that two application areas with different demands on the spatial and temporal resolution can be distinguished: 1) low spatia…

High-Frequency rotablation of occluded coronary artery during heart catheterization

High-frequency rotation atherectomy of an occluded left circumflex coronary artery was performed in a 45-year-old man. Over a 0.009 inch flexible tip steel wire a diamond-coated brass burr fasten to a flexible drive shaft that rotates and tracks was advanced. The drive shaft was connected to a turbine and driven by compressed air with 150,000 rpm. After rotablation of the posterior lateral branch over 3 cm with a 1.5 mm burr and rotablation with a 1.75 mm burr of the posterior branch of the left circumflex coronary artery the vessel was reopened with a smooth surface without perforation and dissection. 24 h control and 6 mo control revealed an open coronary vessel. High frequency rotating c…

Coronary Angioplasty in Unstable Angina

When Gruntzig introduced the revolutionary method of percutaneous transluminal coronary angioplasty (PTCA) for the treatment of coronary artery stenoses, he initially devoted this technique only to patients with stable angina pectoris [8]. Very soon, however, it was discovered simultaneously by Williams et al. [19] and by our group [12] that this method can also be used in patients with unstable angina pectoris. The earliest experiences with PTCA in 1980 were published by our two groups (Table 1). In these series the average degree of stenosis was somewhat lower than that today, while the residual stenosis after treatment was slightly higher. The very rough balloons and guiding catheters av…

Search for new phenomena with the monojet and missing transverse momentum signature using the ATLAS detector in s=7TeV proton–proton collisions

A search for new phenomena in events featuring a high energy jet and large missing transverse momentum in proton-proton collisions at root s = 7 TeV is presented using a dataset corresponding to an integrated luminosity of 33 pb(-1) recorded with the ATLAS detector at the Large Hadron Collider. The number of observed events is consistent with the Standard Model prediction. This result is interpreted in terms of limits on a model of Large Extra Dimensions. (C) 2011 CERN. Published by Elsevier B.V. All rights reserved.

Intraventrikuläre Obstruktionen bei der Dobutamin-Streßechokardiographie: Determinanten ihrer Entstehung und klinische Folgen (Dynamic intraventricular obstruction during dobutamine stress echocardiography. Determinants of the phenomenon and clinical consequences)

Die Dobutamin-Stresechokardiographie (DSE) fuhrt zu einer starken Hyperkontraktilitat des Myokards bei Tachykardie und Vesodilatation. Diese Effekte konnen zu einer unphysiologischen Abnahme des endsystolischen Volumenindex (ESVI) mit Obstruktion des linksventrikularen Ausflustraktes (LVOT) fuhren. Bei 100 Patienten (Pat.), die sich einer DSE (5–40) μg/kg/min) unterzogen, wurde die kontinuierliche Dopplerregistrierung (DW-Doppler) vor Infusion und bei maximaler Herzfrequenz durchgefuhrt. Eine dynamische, spat-systolische, Flusakzeleration auf mehr als 2 Meter/Sekunde (m/s) unter maximaler Stimulation wurde als systolische Obstruktion des LVOT interpretiert. Manifestationsfaktoren systolisch…

High-ET isolated-photon plus jets production in pp collisions at s=8 TeV with the ATLAS detector

The dynamics of isolated-photon plus one-, two- and three-jet production in pp collisions at a centre-of-mass energy of 8 TeV are studied with the ATLAS detector at the LHC using a data set with an ...

Search for the Higgs boson in the H→WW→ℓνjj decay channel at s=7 TeV with the ATLAS detector

A search for the Standard Model Higgs boson has been performed in the H→WW→lνjj channel using 4.7 fb^(−1) of pp collision data recorded at a centre-of-mass energy of √s = 7 TeV with the ATLAS detector at the Large Hadron Collider. Higgs boson candidates produced in association with zero, one or two jets are included in the analysis to maximize the acceptance for both gluon fusion and weak boson fusion Higgs boson production processes. No significant excess of events is observed over the expected background and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 300 GeV<m_H<600 GeV. The best sensitivity is reached for m_H=400 GeV, where the obse…

Search for third generation scalar leptoquarks in pp collisions at √s = 7 TeV with the ATLAS detector

A search for pair-produced third generation scalar leptoquarks is presented, using proton-proton collisions at √s = 7 TeV at the LHC. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 4.7 fb[superscript −1]. Each leptoquark is assumed to decay to a tau lepton and a b-quark with a branching fraction equal to 100%. No statistically significant excess above the Standard Model expectation is observed. Third generation leptoquarks are therefore excluded at 95% confidence level for masses less than 534 GeV.

Clinical relevance of vegetation localization by transoesophageal echocardiography in infective endocarditis

Infective endocarditis is associated with significant morbidity and mortality, with valvular destruction and congestive heart failure being more common in patients with echocardiographically discernible vegetations. The transoesophageal approach affords consistently high quality images with excellent structural resolution. Two-hundred and eighty-one patients with clinically suspected infective endocarditis were studied, to evaluate the prognostic value of ascertaining the site of vegetations. Among them were 118 patients with vegetations attached to the aortic or mitral valve. These patients were followed for a mean period of 14 months. Mitral valve vegetations were associated with a signif…

Single-lead VDD-Systeme: Eine Alternative zu DDD-Systemen bei Patienten mit AV-Block

VDD- und DDD-Systeme in der Therapie des isolierten AV-Blocks werden anhand der Kriterien Implantation und Komplikationen, Sicherheit der atrialen Wahrnehmung, Erhalt der AV-synchronen Stimulation, Notwendigkeit einer atrialen Stimulation, Inzidenz atrialer Rhythmusstorungen und Schrittmachernachsorge gegenubergestellt.

Search for lepton flavour violation in the e mu continuum with the ATLAS detector in root s=7 TeV pp collisions at the LHC

This paper presents a search for the t-channel exchange of an R-parity violating scalar top quark ([~ over t] ) in the e[superscript ±]μ[superscript ∓] continuum using 2.1 fb[superscript −1] of data collected by the ATLAS detector in s√=7 TeV pp collisions at the Large Hadron Collider. Data are found to be consistent with the expectation from the Standard Model backgrounds. Limits on R-parity-violating couplings at 95 % C.L. are calculated as a function of the scalar top mass ( m[subscript bar over t]). The upper limits on the production cross section for pp→eμX, through the t-channel exchange of a scalar top quark, ranges from 170 fb for m[subscript ~ over t]=95 GeV to 30 fb for m[subscrip…

Charged-particle multiplicities in pp interactions measured with the ATLAS detector at the LHC

Measurements are presented from proton–proton collisions at centre-of-mass energies of \sqrt{s} = 0.9 , 2.36 and 7 TeV recorded with the ATLAS detector at the LHC. Events were collected using a single-arm minimum-bias trigger. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the relationship between the mean transverse momentum and charged-particle multiplicity are measured. Measurements in different regions of phase space are shown, providing diffraction-reduced measurements as well as more inclusive ones. The observed distributions are corrected to well-defined phase-space regions, using model-independent corrections. The results are compared…

Hochfrequenz-Rotationsatherektomie bei koronarer Herzkrankheit

Percutaneous high frequency coronary rotational ablation (PTCR) was used in 10 patients with significant coronary artery disease. PTCR removes arteriosclerotic material from the vessel wall. A diamond-coated (60-80 micron) brass burr-drill, fastened to a flexible drive shaft rotating and tracking along a central coaxial guide wire, was used. The turbine rotates the drive shaft in excess of 150,000-190,000 revolutions per minute. PTCR was successful in all patients, but in three additional percutaneous transluminal coronary angioplasty (PTCA) was then successfully performed. Coronary dissection occurred only once, requiring surgery which was successful. No vessel perforation was observed. Al…

SELPLG Gene Polymorphisms in Relation to Plasma SELPLG Levels and Coronary Artery Disease

P-selectin and P-selectin glycoprotein ligand (SELPLG, selectin P ligand) constitute a receptor/ligand complex that is likely to be involved in the development of atherosclerosis and its complications. While the genetic variability of P-selectin has already been investigated in depth, that of the SELPLG gene has not yet been extensively explored. The coding and regulatory sequences of the SELPLG were screened and nine polymorphisms were identified. The identified polymorphisms were genotyped in the AtheroGene study, a case-control study of coronary artery disease (CAD). Haplotype analysis revealed that two polymorphisms of SELPLG, the M62I and the VNTR, independently influenced plasma SELPL…

Search for the Standard Model Higgs Boson in the Missing Energy and Acoplanarb-Jet Topology ats=1.96  TeV

We report a search for the standard model Higgs boson in the missing energy and acoplanar b-jet topology, using an integrated luminosity of 0.93 fb(-1) recorded by the D0 detector at the Fermilab Tevatron p (p) over bar Collider. The analysis includes signal contributions from p (p) over bar -> ZH -> v (v) over barb (b) over bar, as well as from WH production in which the charged lepton from the W boson decay is undetected. Neural networks are used to separate signal from background. In the absence of a signal, we set limits on sigma(p (p) over bar -> VH) x B(H -> b (b) over bar) at the 95% C.L. of 2.6-2.3 pb, for Higgs boson masses in the range 105-135 GeV, where V W, Z. The corresponding …

Measurement of the pseudorapidity and transverse momentum dependence of the elliptic flow of charged particles in lead–lead collisions at sNN=2.76 TeV with the ATLAS detector

This Letter describes the measurement of elliptic flow of charged particles in lead-lead collisions at root s(NN) = 2.76 TeV using the ATLAS detector at the Large Hadron Collider (LHC). The results ...

Cardiac output in single-lead VDD pacing versus rate-matched VVIR pacing.

The importance of atrioventricular synchronous pacing compared with single-chamber rate-responsive pacing is still under discussion, especially for low-intensity workload representing daily life activities. We evaluated hemodynamics in single-lead VDD pacing versus VVIR pacing in 11 patients (8 men and 3 women, aged 58.6 +/- 13.8 years) with normal left ventricular function and a previously implanted single-lead VDDR pacemaker. A low-intensity steady-state treadmill test at 1 to 2.5 mph with a gradient of 2% to 4% was performed. Cardiac output was determined using a standard carbon dioxide rebreathing technique. Initially, the VDD mode was programmed, and after 5 minutes of exercise, cardia…

Readiness of the ATLAS Tile Calorimeter for LHC collisions

67 páginas.-- El PDF es la versión pre-print (arXiv:1007.5423v2).-- The ATLAS Collaboration.-- et al.

Search for techniparticles in e +jets events at D0

We search for the technicolor process ppbar -&gt; rho_T/omega_T -&gt;W+pi_T in events containing one electron and two jets, in data corresponding to an integrated luminosity of 390 pb-1, recorded by the D0 experiment at the Fermilab Tevatron. Technicolor predicts that technipions, pi_T, decay dominantly into b-bbar, b-cbar, or bbar-c, depending on their charge. In these events b and c quarks are identified by their secondary decay vertices within jets. Two analysis methods based on topological variables are presented. Since no excess above the standard model prediction was found, the result is presented as an exclusion in the pi_T vs. rho_T mass plane for a given set of model parameters.

Measurement of the inclusive jet cross-section in pp collisions at $\sqrt{s}=2.76\ \mbox{TeV}$ and comparison to the inclusive jet cross-section at $\sqrt{s} =7\ \mbox{TeV}$ using the ATLAS detector

The inclusive jet cross-section has been measured in proton-proton collisions at sqrt(s)=2.76 TeV in a dataset corresponding to an integrated luminosity of 0.20pb-1 collected with the ATLAS detector at the Large Hadron Collider in 2011. Jets are identified using the anti-kt algorithm with two radius parameters of 0.4 and 0.6. The inclusive jet double-differential cross-section is presented as a function of the jet transverse momentum pT and jet rapidity y, covering a range of 20 &lt;= pT &lt; 430 GeV and |y| &lt; 4.4. The ratio of the cross-section to the inclusive jet cross-section measurement at sqrt(s)=7 TeV, published by the ATLAS Collaboration, is calculated as a function of both trans…

Intrakoronare Interventionen in der Fr�hinfarktphase

Wahrend die intravenose Thrombolysetherapie weiterhin als Goldstandard der Reperfusionsbehandlung des akuten Myokardinfarktes gilt, sind in den vergangenen Jahren auch zunehmend mechanische Reperfusionsstrategien untersucht worden. Zunachst wurde das Konzept der routinemasigen Sofort-PTCA nach Thrombolysebehandlung untersucht, das wegen einer hoheren Komplikationsrate im Vergleich zur alleinigen Thrombolysetherapie jedoch keine Verbreitung fand. Beim Konzept der Rescue-PTCA erfolgt eine mechanische Rekanalisation und Dilatation nur im Falle eines dokumentierten persistierenden Gefasverschlusses nach Thrombolysetherapie. Fur dieses Konzept konnte eine verbesserte Uberlebensrate und Ventrikel…

Detection of dissection of the aortic intima and media after angioplasty of coarctation of the aorta. An angiographic, computer tomographic, and echocardiographic comparative study.

Balloon coarctation angioplasty (BCA) was performed in eight patients (five male and three female) who were 14-49 years old (mean, 27.3 years) with isolated discrete unoperated coarctation of the aorta (n = 7) and postoperative recoarctation (n = 1). BCA was successful in seven of eight patients, resulting in a decrease in the gradient (64 +/- 19 to 16 +/- 13 mm Hg, p less than 0.01), an increase in the diameter at the coarctation site (0.9 +/- 0.4 to 1.6 +/- 0.4 mm, p less than 0.01). Follow-up (6 months) has demonstrated continued gradient relief (6 +/- 9 mm Hg) and diameter increase (1.6 +/- 0.2 cm). Monitoring was performed by transesophageal echocardiography (TEE) during BCA, and befor…

Search for top and bottom squarks from gluino pair production in final states with missing transverse energy and at least three b-jets with the ATLAS detector

This letter reports the results of a search for top and bottom squarks from gluino pair production in 4.7 fb[superscript −1] of pp collisions at s√=7 TeV using the ATLAS detector at the LHC. The search is performed in events with large missing transverse momentum and at least three jets identified as originating from a b-quark. Exclusion limits are presented for a variety of gluino-mediated models with gluino masses up to 1 TeV excluded.

Spectral estimators for Doppler analysis of intracoronary ultrasound catheters

With the zero-cross-detection method (ZCD) it has been shown that it is not possible to achieve a reproducible quantitative, and robust evaluation of an inter-coronary audio signal. The authors define spectral estimators to analyze the Doppler-audio signal. Measurements in a blood flow model have shown that the ZCD method underestimates the expected velocity at all speeds. Spectral analysis allows the determination of the actual and peak velocity more robustly and precisely. >

Hämodynamik nach sublingualer Applikation von Captopril bei schwerer Herzinsuffizienz*: Eine Pilotstudie

In a preliminary trial, 23 patients in severe left-heart failure and, in some instances, also right-heart failure (NYHA classes III and IV) received a single sublingual dose of 25 mg captopril. Invasive measurement of various haemodynamic parameters indicated (1) an increase in cardiac index and stroke-volume index of 34% and 38%, respectively (P less than 0.001 for each); (2) decrease in pulmonary artery and systemic pressures by an average of 7% and 11.4% (P less than 0.01 and less than 0.001, respectively); (3) no significant change in heart rate and mean right atrial pressure; (4) decrease in systemic and pulmonary artery resistance by 33% and 29% (P less than 0.001 for both); (5) an in…

Measurement of the ratios of the Z/γ∗+⩾n jet production cross sections to the total inclusive Z/γ∗ cross section in pp¯ collisions at s=1.96 TeV

We present a study of events with Z bosons and jets produced at the Fermilab Tevatron Collider in ppbar collisions at a center of mass energy of 1.96 TeV. The data sample consists of nearly 14,000 Z/G* -> e+e- candidates corresponding to the integrated luminosity of 340 pb-1 collected using the D0 detector. Ratios of the Z/G* + >= n jet cross sections to the total inclusive Z/G* cross section have been measured for n = 1 to 4 jet events. Our measurements are found to be in good agreement with a next-to-leading order QCD calculation and with a tree-level QCD prediction with parton shower simulation and hadronization.

Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion.

Background Myocardial injury from ischemia can be aggravated by reperfusion of the jeopardized area. The precise underlying mechanisms have not been clearly defined, but proinflammatory events, including complement activation, leukocyte adhesion, and infiltration and release of diverse mediators, probably play important roles. The present study addresses the possibility of reducing reperfusion damage by the application of C1 esterase inhibitor (C1-INH). Methods and Results Cardioprotection by C1-INH 20 IU/kg IC was examined in a pig model with 60 minutes of coronary occlusion, followed by 120 minutes of reperfusion. C1-INH was administered during the first 5 minutes of coronary reperfusion…

Normalwerte für die Dobutamin-Streßechokardiographie*

UNLABELLED Dobutamine stress echocardiography having established itself as a sensitive method for diagnosing coronary heart disease, even in the absence of normative values, the physiological haemodynamics as well as the physiological values for global and regional left ventricular myocardial function were measured. TEST PERSONS AND METHODS 14 healthy subjects (ten men, four women; median age 25 [range 21-32] years) underwent dobutamine stress echocardiography according to an internationally practised dosage steps protocol (5-40 micrograms/kg/min with additional 0.5 mg atropine at 40 micrograms). RESULTS Maximal infusion rate achieved a serum dobutamine level of 1.67 micrograms/ml with mini…

Measurement of the Semileptonic Branching Ratio ofBs0to an Orbitally ExcitedDs**State:Br(Bs0→Ds1−(2536)μ+νX)

In a data sample of approximately 1.3 fb-1 collected with the D0 detector between 2002 and 2006, the orbitally excited charm state D_s1(2536) has been observed with a measured mass of 2535.7 +/- 0.6 (stat) +/- 0.5 (syst) MeV via the decay mode B0_s -> D_s1(2536) mu nu X. A first measurement is made of the branching ratio product Br(b(bar) -> D_s1(2536) mu nu X).Br(D_s1(2536)->D* K0_S). Assuming that D_s1(2536) production in semileptonic decay is entirely from B0_s, an extraction of the semileptonic branching ratio Br(B0_s -> D_s1(2536) mu nu X) is made.

Search for same-sign top-quark production and fourth-generation down-type quarks in pp collisions at √s = 7 TeV with the ATLAS detector

A search is presented for same-sign top-quark production and down-type heavy quarks of charge −1/3 in events with two isolated leptons (e or μ) that have the same electric charge, at least two jets and large missing transverse momentum. The data are selected from pp collisions at √s=7TeV recorded by the ATLAS detector and correspond to an integrated luminosity of 1.04 fb−1. The observed data are consistent with expectations from Standard Model processes. Upper limits are set at 95 % confidence level on the cross section of new sources of same-sign top-quark pair production of 1.4-2.0 pb depending on the assumed mediator mass. Upper limits are also set on the pair-production cross-section fo…

Forward-backward correlations and charged-particle azimuthal distributions in $pp$ interactions using the ATLAS detector

Using inelastic proton-proton interactions at sqrt(s) = 900 GeV and 7 TeV, recorded by the ATLAS detector at the LHC, measurements have been made of the correlations between forward and backward charged-particle multiplicities and, for the first time, between forward and backward charged-particle summed transverse momentum. In addition, jet-like structure in the events is studied by means of azimuthal distributions of charged particles relative to the charged particle with highest transverse momentum in a selected kinematic region of the event. The results are compared with predictions from tunes of the PYTHIA and HERWIG++ Monte Carlo generators, which in most cases are found to provide a r…

Search for the lightest scalar top quark in events with two leptons in pp¯ collisions at s=1.96 TeV

Abstract We report results of a search for the pair production of the lightest supersymmetric partner of the top quark, t ˜ 1 , using a data set corresponding to an integrated luminosity of 1 fb −1 collected by the DO detector at a p p ¯ center-of-mass energy of 1.96 TeV at the Fermilab Tevatron collider. Both scalar top quarks are assumed to decay into a b quark, a charged lepton and a scalar neutrino. The search is performed in the electron plus muon and dielectron final states. The signal topology consists of two isolated leptons, missing transverse energy, and jets. We find no evidence for this process and exclude regions of parameter space in the framework of the minimal supersymmetric…

Diagnosis of papillary muscle rupture after acute myocardial infarction by transthoracic and transesophageal echocardiography.

The sensitivity of transthoracic echocardiography to visualize the structural abnormality of papillary muscle rupture (PMR) after acute myocardial infarction can be anticipated to average about 50%; therefore, we evaluated five patients exhibiting the condition with both transthoracic and transesophageal echocardiography. The use of the two imaging techniques resulted in the fact that no instance of PMR was missed. Using transthoracic echocardiography in two patients and transesophageal echocardiography in four, the ruptured papillary muscle was visualized directly. Mitral insufficiency as an indirect sign was observed in all patients. In one patient the papillary muscle rupture developed i…

Depiction of anomalous coronary vessels and their relation to the great arteries by magnetic resonance angiography

Three-dimensional respiratory-gated coronary MR angiography (MRA) allowed accurate analysis of the anatomy of the coronary arteries and their relation to the adjacent anatomic structures in two patients with anomalous origin and proximal course of the coronary vessels. Together with functional tests, it decisively influenced further therapy.

Monitoring prothrombin fragment 1+2 during initiation of oral anticoagulant therapy after intracoronary stenting

Patients with intracoronary stent implantation are treated with aggressive anticoagulant and antiplatelet therapy consisting of high-dose heparin, phenprocoumon, acetylsalicylic acid, dipyridamole, and the infusion of dextran to prevent a subacute thrombotic occlusion of the stented segment. In an effort to optimize this treatment by reducing both imminent bleeding complications and subacute thrombotic occlusion, the concentrations of prothrombin fragment 1 + 2 (F 1 + 2) were determined after intracoronary Palmaz-Schatz stent implantation in 19 consecutive patients. The F 1 + 2 concentrations after stent implantation and before the initiation of oral anticoagulant therapy (OAT) were 0.35 nm…

Combination of CDF and D0 measurements of the W boson helicity in top quark decays

Aaltonen, T. et al.

Tissue classification by texture and spectral analysis of intracoronary ultrasound radio-frequency data

Imaging of vascular structures by intracoronary ultrasound allows in principal the recognition of different lesion types due to the echomorphology in the B-mode image. The subjective visual diagnosis is often difficult, especially the differentiation between thrombi and non-calcified plaque. The aim of this study was the extraction of features from the ultrasound radio-frequency signal for an objective characterization of coronary tissue. Methods of texture analysis and frequency analysis were used to differentiate red and white thrombi in vitro. Eight texture parameters of first and second order significantly differentiated red and white thrombi. The backscatter transfer function of red th…

Search for displaced muonic lepton jets from light Higgs boson decay in proton–proton collisions at s=7 TeV with the ATLAS detector

A search is performed for collimated muon pairs displaced from the primary vertex produced in the decay of long-lived neutral particles in proton-proton collisions at root s = 7 TeV centre-of-mass ...

FRIPON: a worldwide network to track incoming meteoroids

Context. Until recently, camera networks designed for monitoring fireballs worldwide were not fully automated, implying that in case of a meteorite fall, the recovery campaign was rarely immediate. This was an important limiting factor as the most fragile - hence precious - meteorites must be recovered rapidly to avoid their alteration. Aims. The Fireball Recovery and InterPlanetary Observation Network (FRIPON) scientific project was designed to overcome this limitation. This network comprises a fully automated camera and radio network deployed over a significant fraction of western Europe and a small fraction of Canada. As of today, it consists of 150 cameras and 25 European radio receiver…

Emergency angioplasty of totally occluded left main coronary artery in acute myocardial infarction and unstable angina pectoris--institutional experience and literature review.

Acute occlusion of the left main coronary artery (LMCA) is a rare angiographic finding. We report five patients with acute myocardial infarction (AMI) and one patient with unstable angina, in whom reperfusion was achieved or attempted with percutaneous transluminal coronary angioplasty (PTCA). All patients had a long history of stable angina pectoris. The indication for emergency PTCA was cardiogenic shock in the five patients with MI. PTCA was successful in five of six patients. Three patients with reperfusion survived, three died. All survivors underwent coronary artery bypass grafting (CABG) and were still alive at 23 months, 3 and 8 years respectively in NYHA functional class II or III.…

Search for pair production of second generation scalar leptoquarks

We report on a search for the pair production of second generation scalar leptoquarks (LQ) in ppbar collisions at the center of mass energy sqrt(s)=1.96 TeV using a data set corresponding to an integrated luminosity of 1.0 fb-1 collected with the D0 experiment at the Fermilab Tevatron Collider. Topologies arising from the LQLQbar-&gt;muqnuq and LQLQbar-&gt;muqmuq decay modes are investigated. No excess of data over the standard model prediction is observed and upper limits on the leptoquark pair production cross section are derived at the 95% C.L. as a function of the leptoquark mass and the branching fraction beta for the decay LQ-&gt;muq. These are interpreted as lower limits on the lepto…

Enhanced detection of contrast regions in echocardiograms by adaptive quantization

The statistics of ultrasound echo images are governed by Rayleigh statistics. The authors derive some experimentally verifiable predictions of this theory, compare them with experimental results obtained from echocardiographic images, and derive a new color coding scheme, (adaptive quantization) that is adapted to the signal-dependent noise predicted by theory. This results in some technical advantages and in an improved discrimination of regions of the echo image that are enhanced by echo contrast material. >

Search for direct slepton and gaugino production in final states with two leptons and missing transverse momentum with the ATLAS detector in pp collisions at

A search for the electroweak pair production of charged sleptons and weak gauginos decaying into final states with two leptons is performed using 4.7 fb(-1) of proton-proton collision data at root s = 7 TeV recorded with the ATLAS experiment at the Large Hadron Collider. No significant excesses are observed with respect to the prediction from Standard Model processes. In the scenario of direct slepton production, if the sleptons decay directly into the lightest neutralino, left-handed slepton masses between 85 and 195 GeV are excluded at 95% confidence level for a 20 GeV neutralino. Chargino masses between 110 and 340 GeV are excluded in the scenario of direct production of wino-like chargi…

Measurement of t ¯ t production with a veto on additional central jet activity in pp collisions at √ s = 7 TeV using the ATLAS detector

A measurement of the jet activity in t[bar over t] events produced in proton–proton collisions at a centre-of-mass energy of 7 TeV is presented, using 2.05 fb[superscript −1] of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. The t[bar over t] events are selected in the dilepton decay channel with two identified b-jets from the top quark decays. Events are vetoed if they contain an additional jet with transverse momentum above a threshold in a central rapidity interval. The fraction of events surviving the jet veto is presented as a function of this threshold for four different central rapidity interval definitions. An alternate measurement is also perfor…

Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis.

Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities. Our aim was to determine whether PAF-AH activity was associated with inflammatory markers and with coronary artery disease (CAD). PAF-AH activity and a panel of inflammatory mediators were measured in plasma of 496 patients with CAD and in 477 controls; 276 patients presented with stable angina pectoris and 220 with acute coronary syndrome (ACS). Individuals within the highest quartile of PAF-AH activity had an 1.8-fold increase in CAD risk [95% confidence interval (CI), 1.01 to 3.2; P = 0.…

Clinical predictors of unstable coronary lesion morphology.

We evaluated prospectively clinical and angiographic data in 400 patients, 200 with unstable and 200 with stable angina in order to determine which clinical markers could reliably predict unstable coronary artery lesions. Comparison of the angiogram of 200 patients with unstable and 200 with stable angina revealed a high-grade lesion (42% vs 23%, P < 0.0001), complex lesion morphology (49% vs 20%, P < 0.0001) and thrombus-containing lesions (7% vs 1%, P = 0.006) as typical findings in patients with unstable angina. A high-grade lesion and/or complex lesion (including thrombotic lesions but excluding total occlusion) was found in 61% of unstable and 34% of stable patients (P < 0.0001). Clini…

Residual coronary stenosis after thrombolysis with rt-PA or streptokinase: acute results and 3 weeks follow-up

Ninety-one patients with acute myocardial infarction were assigned to intravenous treatment with streptokinase or rt-PA as part of the randomized trial carried out by the European Study Group for Recombinant Tissue-Type Plasminogen Activator (rt-PA). A patent coronary artery was found in 37 of 45 (82%) patients treated with rt-PA and in 27 of 46 (59%) patients treated with streptokinase 75-90 minutes after start of infusion. Patients were subsequently anticoagulated with heparin or dicoumarol up to a repeat angiography 3 weeks after the infarction. Of the 64 patients with successful reperfusion, 3 died and 3 suffered reocclusion of the vessel. Quantitative analysis of the coronary stenosis …

Extended Skyrme pseudo-potential deduced from infinite matter properties

We discuss the contributions to the Equation of State for the N$\ell$LO Skyrme pseudo-potential ($\ell$=2,3). We show that by adding 4th and 6th order gradient terms, it is possible to fairly reproduce the spin/isospin decomposition of an equation of state obtained from \emph{ab-initio} methods. Moreover, by inspecting the partial-wave decomposition of the equation of state, we show for the first time a possible way to add explicit constraints on the sign of the tensor terms of the Skyrme interaction.

Erratum to: “Search for particles decaying into a Z boson and a photon in pp¯ collisions at s=1.96 TeV” [Phys. Lett. B 641 (2006) 415]

Search for particles decaying into a Z boson and a photon in collisions p (p)over-bar at root s = 1.96 TeV (vol 641, pg 415, 2006)

Charged-particle multiplicities in pp interactions at s=900 GeV measured with the ATLAS detector at the LHC

The first measurements from proton-proton collisions recorded with the ATLAS detector at the LHC are presented. Data were collected in December 2009 using a minimum-bias trigger during collisions at a centre-of-mass energy of 900 GeV. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity, and the relationship between mean transverse momentum and charged-particle multiplicity are measured for events with at least one charged particle in the kinematic range vertical bar eta vertical bar 500 MeV. The measurements are compared to Monte Carlo models of proton-proton collisions and to results from other experiments at the same centre-of-mass energy. The charg…

Detection of coronary artery calcifications predicting coronary heart disease: comparison of fluoroscopy and spiral CT.

The aim of this study was to evaluate the clinical relevance of coronary artery calcifications detected by spiral CT, congruence with fluoroscopy (FS) and coronary angiography, and comparison with studies reporting on application of double-helical CT and ultrafast CT. Forty patients underwent spiral CT (2-mm slice thickness, table feed 3 mm/s), coronary angiography, and FS (performed in the usual manner). Stenosis and calcifications were evaluated semiquantitatively. Nineteen patients suffering from a stenosis ≥ 75 % were verified at coronary angiography. All had coronary artery calcification on spiral CT. Fluoroscopy did not detect 8 of 19 patients with a stenosis ≥ 75 % (1 vessel: n = 1; …

Densitometry and parametric imaging with quality control

X-ray contrast image series of the myocardium were studied using the approaches of densitometry and parametric imaging accompanied by quality control. Contrast angiograms were digitized at six predefined phases of the heart cycle. For densitometry, regions of interest (ROIs) were defined semi-automatically for all phases. The resulting six densograms were summed up and weighted according to their quality determined by a measure. Previously validated parameters such as rise time were calculated. The enddiastolic images were only used for the calculation of color-coded parametric images accompanied by pixel-densogram-quality information. An observer gives a score for the perfusion of roughly …

“Three-level shock” in ablation-refractory paroxysmal atrial fibrillation

His-bundle ablation is a very effective method to control drug-refractory supraventricular arrhythmias. We present a 69-year-old woman with paroxysmal atrial fibrillation, in whom several attempts of unipolar and bipolar His-bundle ablation were ineffective. Ultimately a stable 2/1 atrioventricular block was induced when three successive shocks of 400 W were applied. The first shock was given in that position with the largest His-potential deflection. The other two shocks were applied at catheter positions more distal and more proximal from the first one, respectively. We suppose that the initial lack of success was due to an atypical atrioventricular junction anatomy.

Search for strong gravity signatures in same-sign dimuon final states using the ATLAS detector at the LHC

A search for microscopic black holes has been performed in a same-sign dimuon final state using 1.3 fb[superscript −1] of proton–proton collision data collected with the ATLAS detector at a centre of mass energy of 7 TeV at the CERN Large Hadron Collider. The data are found to be consistent with the expectation from the Standard Model and the results are used to derive exclusion contours in the context of a low scale gravity model.

Non-invasive determination of cardiac output by transesophageal Doppler ultrasound-clinical application and validation

The authors describe the development and validation of a device using transesophageal (TE) Doppler ultrasound to provide continuous and noninvasive monitoring of cardiac output (CO) and related parameters. In intubated and artificially ventilated patients who underwent pulmonary artery catherization for hemodynamic monitoring, CO was determined by the esophageal Doppler ultrasound probe and compared to the results obtained simultaneously by means of thermodilution. A very close correlation was found between the results (r=0.99), with a standard estimate of error less than 5% as well as good reproducibility (r=0.96 and r=0.98). >

Search for Gluinos in Events with Two Same-Sign Leptons, Jets, and Missing Transverse Momentum with the ATLAS Detector in Collisions at

A search is presented for gluinos decaying via the supersymmetric partner of the top quark using events with two same-sign leptons, jets, and missing transverse momentum. The analysis is performed ...

Modernes Reperfusionsmanagement bei akutem Myokardinfarkt

In der Regel liegt dem transmuralen Myokardinfarkt (ST-Hebungsinfarkt) die Ruptur einer atherosklerotischen Plaque mit nachfolgend thrombotischem Verschluss einer Koronararterie zugrunde. Seit Beginn der 1980er Jahre hat die Reperfusionstherapie bei akutem Myokardinfarkt zunehmend Eingang in die klinische Routine gefunden. Als Standardtherapie hat sich die intravenose Thrombolysetherapie durchgesetzt. Je fruhzeitiger die Reperfusion einsetzt, um so mehr Myokardgewebe kann vor der drohenden Nekrose bewahrt werden. Diese erzielbare Verringerung der Infarktgrose geht mit einer Verringerung der sonst drohenden linksventrikularen Funktionseinschrankung und einer Abnahme der Letalitat einher. Let…

Measurement of the isolated photon cross section in pp¯ collisions at s=1.96 TeV

The cross section for the inclusive production of isolated photons has been measured in p anti-p collisions at sqrt{s}=1.96 TeV with the D0 detector at the Fermilab Tevatron Collider. The photons span transverse momenta 23 to 300 GeV and have pseudorapidity |eta|<0.9. The cross section is compared with the results from two next-to-leading order perturbative QCD calculations. The theoretical predictions agree with the measurement within uncertainties.

Erratum to: “Measurement of the isolated photon cross section in pp¯ collisions at s=1.96 TeV” [Phys. Lett. B 639 (2006) 151]

Measurement of the isolated photon cross section in p(p)over-bar collisions at root s = 1.96 TeV (vol 639, pg 151, 2006)

Search for the Standard Model Higgs boson in the H→WW(⋆)→ℓνℓν decay mode with 4.7 fb−1 of ATLAS data at s=7 TeV

A search for the Standard Model Higgs boson in the H -> WW(*()) -> lvlv (l = e.mu) decay mode is presented. The search is performed using proton-proton collision data corresponding to an inte ...

Search for a standard model Higgs boson in the H→ZZ→ℓ+ℓ−νν¯ decay channel using 4.7 fb−1 of s=7 TeV data with the ATLAS detector

A search for a Standard Model Higgs boson decaying via H -> ZZ -> l(+)l(-) nu(nu) over bar, where l represents electrons or muons, is presented. It is based on proton-proton collision data at ...

Search for a Higgs boson produced in association with a Z boson

We describe a search for the Standard Model Higgs boson with a mass of 105 GeV/c(2) to 145 GeV/c(2) in data corresponding to an integrated luminosity of approximately 450 pb(-1) collected with the D phi detector at the Fermilab Tevatron p (p) over bar collider at a center-of-mass energy of 1.96 TeV. The Higgs boson is required to be produced in association with a Z boson, and the Z boson is required to decay to either electrons or muons with the Higgs boson decaying to a b (b) over bar pair. The data are well described by the expected background, leading to 95% confidence level cross section upper limits sigma (p (p) over bar -> ZH) x B(H -> b (b) over bar) in the range of 3.1 pb to 4.4 pb.

Einfluß von qualitativen Stenosecharakteristika auf die Meßqualität verschiedener QCA-Systeme (Impact of lesion characteristics on the quality of measurements with different QCA systems)

Die neueren QCA-Systeme weisen bei In-vitro-Messungen eine vergleichbare Reproduzierbarkeit und Genauigkeit der Mesergebnisse auf. Wir untersuchten, welchen Einflus die Morphologie von Koronararterienstenosen und die Bildqualitat auf die Mesergebnisse von drei fuhrenden QCA-Systemen (AWOS, Cardio und CMS) hat. Hierzu wahlten wir 57 Stenosen aus, die eine klinisch reprasentative Verteilung bezuglich des Stenosegrades, verschiedener Lasionscharakteristika und der Bildqualitat aufwiesen. Prozedurale Fehlerquellen wurden, soweit moglich, eliminiert. Drei Untersucher fuhrten je Stenose funf Messungen mit jedem der drei Systeme durch. Bei drei Stenosen war eine Auswertung nicht moglich.

Diagnose eines intramyokardialen Hämatoms nach traumatischem Myokardinfarkt durch Magnetresonanztomographie

Thoraxverletzungen treten bei etwa 30% aller traumatisierten Patienten auf, wobei in den meisten Fallen Verkehrsunfalle die Ursache sind. Wir berichten uber den Fall eines Patienten, der nach einem Skiunfall einen traumatischen Vorderwandinfarkt erlitt. Im weiteren Verlauf kam es zu einer ausgedehnten intramyokardialen Einblutung. Differentialdiagnostisch kam zunachst ein linksventrikulares Pseudo- bzw. Pseudopseudoaneurysma in Frage, kernspintomographisch konnte jedoch durch den Nachweis eines schmalen Myokardsaums sowohl ventral als auch dorsal der Raumforderung die Diagnose eines intramyokardialen Hamatoms gestellt werden. Bei dem Patienten wurde daraufhin eine aortokoronare Bypass-Opera…

Reliability and Accuracy of Echocardiography for Follow-up Studies after Intervention

By two-dimensional echocardiography limitations of M-mode echocardiography have been eliminated. As a direct and noninvasive method two-dimensional echocardiography seems to be an ideal method for analysis of left ventricular function in follow-up studies. In relation to other methods there are no limitations concerning x-ray exposure, physicians and patients safety. Before different studies can be discussed, reliability and accuracy of two-dimensional echocardiography have to be evaluated. Beat-to-beat, day-to-day, intra- and interobserver variability will be discussed, followed by description of follow-up studies after intervention.

VDD(R)-Stimulation mit Mode-Switch bei paroxysmalem Vorhofflimmern und AV-Block: Verlauf über 2 Jahre

Search for a heavy narrow resonance decaying to eμ, eτ, or μτ with the ATLAS detector in s=7 TeV pp collisions at the LHC

This Letter presents the results of a search for a heavy particle decaying into an e^±μ^∓e^±μ^∓, or μ^±τ^∓ final state in pp collisions at View the MathML sources=7 TeV. The data were recorded with the ATLAS detector at the LHC during 2011 and correspond to an integrated luminosity of 4.6 fb−14.6 fb^(−1). No significant excess above the Standard Model expectation is observed, and exclusions at 95% confidence level are placed on the cross section times branching ratio for the production of an R-parity-violating supersymmetric tau sneutrino. For a sneutrino mass of 500 (2000) GeV, the observed limits on the production cross section times branching ratio are 3.2 (1.4) fb, 42 (17) fb, and 40 (1…

Measurement of the production cross section of jets in association with a Z boson in pp collisions at $\sqrt{s}$ = 7 TeV with the ATLAS detector

Measurements of the production of jets of particles in association with a Z boson in pp collisions at s√ = 7 TeV are presented, using data corresponding to an integrated luminosity of 4.6 fb[superscript −1] collected by the ATLAS experiment at the Large Hadron Collider. Inclusive and differential jet cross sections in Z events, with Z decaying into electron or muon pairs, are measured for jets with transverse momentum p [subscript T] > 30 GeV and rapidity |y| < 4.4. The results are compared to next-to-leading-order perturbative QCD calculations, and to predictions from different Monte Carlo generators based on leading-order and next-to-leading-order matrix elements supplemented by parton sh…

ATLAS measurements of the properties of jets for boosted particle searches

Measurements are presented of the properties of high transverse momentum jets, produced in proton-proton collisions at a center-of-mass energy of √s=7  TeV. The data correspond to an integrated luminosity of 35  pb−1 and were collected with the ATLAS detector in 2010. Jet mass, width, eccentricity, planar flow and angularity are measured for jets reconstructed using the anti-kt algorithm with distance parameters R=0.6 and 1.0, with transverse momentum pT>300  GeV and pseudorapidity |η|<2. The measurements are compared to the expectations of Monte Carlo generators that match leading-logarithmic parton showers to leading-order, or next-to-leading-order, matrix elements. The generators describ…

Search for a heavy neutral particle decaying into an electron and a muon using 1 fb−1 of ATLAS data

A search is presented for a high mass neutral particle that decays directly to the e±μ∓ final state. The data sample was recorded by the ATLAS detector in s√=7~TeVpp collisions at the LHC from March to June 2011 and corresponds to an integrated luminosity of 1.07 fb−1. The data are found to be consistent with the Standard Model background. The high e±μ∓ mass region is used to set 95% confidence level upper limits on the production of two possible new physics processes: tau sneutrinos in an R-parity violating supersymmetric model and Z′-like vector bosons in a lepton flavor violating model.

Manifestation und Therapie von Reperfusionsarrhythmien bei der Thrombolyse des akuten Myokardinfarktes

Schon seit 1943 ist bekannt, das die Wiederherstellung der Durchlassigkeit eines verschlossenen Kranzgefases zu Rhythmusstorungen fuhren kann (9). Diese Art von Rhythmusstorungen werden Reperfusionsarrhythmien genannt. Seitdem die intrakoronare und intravenose Streptokinaseapplikation bei Patienten mit frischem Herzinfarkt immer haufiger verabreicht werden, ist auch das Interesse fur die Reperfusionsarrhythmien gestiegen.

Multi-channel search for squarks and gluinos in root s=7 TeV pp collisions with the ATLAS detector at the LHC

A search for supersymmetric particles in final states with zero, one, and two leptons, with and without jets identified as originating from b-quarks, in 4.7 fb[superscript −1] of √s = 7 TeV pp collisions produced by the Large Hadron Collider and recorded by the ATLAS detector is presented. The search uses a set of variables carrying information on the event kinematics transverse and parallel to the beam line that are sensitive to several topologies expected in supersymmetry. Mutually exclusive final states are defined, allowing a combination of all channels to increase the search sensitivity. No deviation from the Standard Model expectation is observed. Upper limits at 95 % confidence level…

Measurement of the top quark charge in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

A measurement of the top quark electric charge is carried out in the ATLAS experiment at the Large Hadron Collider using 2.05 fb[superscript −1] of data at a centre-of-mass energy of 7 TeV. In units of the elementary electric charge, the top quark charge is determined to be 0.64 ± 0.02 (stat.) ± 0.08 (syst.) from the charges of the top quark decay products in single lepton t[¯ over t] candidate events. This excludes models that propose a heavy quark of electric charge −4/3, instead of the Standard Model top quark, with a significance of more than 8σ.

Effects of combined therapy of clopidogrel and aspirin in preventing thrombus formation on mechanical heart valves in an ex vivo rabbit model.

Abstract Background: The aim of our study was to investigate the efficacy of the combination of clopidogrel and aspirin in the prevention of thrombus formation on artificial heart valves in an experimental rabbit model as compared to anticoagulation with warfarin. Methods: Studies were performed after oral administration of clopidogrel and aspirin in group I (n=9) for 5 days, after 5±2 days treatment with warfarin in group II (n=9) and without medication in group III (n=9). Leaflets from Sulzer Carbomedics bileaflet valves were placed in a flow chamber. The flow chamber was filled with blood in a continuous circulation between the carotid artery and the jugular vein. Results: In group III, …

Measurement of the forward-backward asymmetries in the production ofΞandΩbaryons inpp¯collisions

We measure the forward-backward asymmetries $A_{\rm FB}$ of charged $\Xi$ and $\Omega$ baryons produced in $p \bar{p}$ collisions recorded by the D0 detector at the Fermilab Tevatron collider at $\sqrt{s} = 1.96$ TeV as a function of the baryon rapidity $y$. We find that the asymmetries $A_{\rm FB}$ for charged $\Xi$ and $\Omega$ baryons are consistent with zero within statistical uncertainties.

Analysis of high-frequency rotational angioplasty-induced echo contrast.

During high-frequency rotational angioplasty (HFRA), myocardial contrast enhancement (echo contrast) was observed by means of two-dimensional echocardiography. In order to evaluate the echo contrast produced by HFRA, an in vitro experimental model was built using a cylinder with the HFRA catheter scanned in a water bath. The cylinder was filled with blood, mineral water, and distilled water. With a 2.5-MHz transducer, echograms were recorded and analyzed by video intensitometer, and the maximum intensity IUmax and persistence time P were calculated. Rotation frequencies of 20,000-200,000 rpm with 2.0--mm burrs and times of 10 s were tested. In another model, hyperbaric conditions for the sa…

Isolated in-vitro perfusion of pig hearts obtained from the abattoir: an alternative to animal experiments?

Isolated pig hearts (German farm pigs) were characterized after global in-vivo ischaemia as a potential alternative to in-vivo animal studies. Hearts were harvested from adult farm swine at the abattoir 10.3 +/- 2.1 min after incision of the carotid artery. They were immediately perfused and thereafter stored in ice-cold cardioplegic (St Thomas's) solution. After 38 +/- 3 min, retrograde perfusion was started with oxygenated pig blood (37 degrees C; 5000 U Heparin.l-1; pH 7.38 +/- 0.1; 11 mmol glucose.l-1) at a flow rate of 85 ml.min-1 100 g-1 wet weight (gww-1) for 30 min (n = 10). Additionally, shortly after obtaining the hearts, ATP and CP content were measured by enzymatic tests in 10 p…

Hunt for new phenomena using large jet multiplicities and missing transverse momentum with ATLAS in 4.7 fb[superscript −1] of √s = 7 TeV proton-proton collisions

Results are presented of a search for new particles decaying to large numbers of jets in association with missing transverse momentum, using 4.7 fb[superscript −1] of pp collision data at √s = 7 TeV collected by the ATLAS experiment at the Large Hadron Collider in 2011. The event selection requires missing transverse momentum, no isolated electrons or muons, and from ≥6 to ≥9 jets. No evidence is found for physics beyond the Standard Model. The results are interpreted in the context of a MSUGRA/CMSSM supersymmetric model, where, for large universal scalar mass m [subscript 0], gluino masses smaller than 840 GeV are excluded at the 95% confidence level, extending previously published limits.…

Measurement of inclusive jet and dijet cross sections in proton-proton collisions at 7 TeV centre-of-mass energy with the ATLAS detector

Jet cross sections have been measured for the first time in proton-proton collisions at a centre-of-mass energy of 7 TeV using the ATLAS detector. The measurement uses an integrated luminosity of 17 nb−1 recorded at the Large Hadron Collider. The anti-k t algorithm is used to identify jets, with two jet resolution parameters, R=0.4 and 0.6. The dominant uncertainty comes from the jet energy scale, which is determined to within 7% for central jets above 60 GeV transverse momentum. Inclusive single-jet differential cross sections are presented as functions of jet transverse momentum and rapidity. Dijet cross sections are presented as functions of dijet mass and the angular variable χ. The res…

Zγ production and limits on anomalous ZZγ and Zγγ couplings in pp¯ collisions at s=1.96 TeV

We present a study of eey and mu mu gamma events using 1109 (1009) pb-(1) of data in the electron (muon) channel, respectively. These data were collected with the DO detector at the Fermilab Tevatron pp collider at Is = 1.96 TeV. Having observed 453 (515) candidates in the eey (jtAy) final state, we measure the Z gamma production cross section for a photon with transverse energy ET > 7 GeV, separation between the photon and leptons Delta Rey > 0.7, and invariant mass of the di-lepton pair Mee > 30 GeV/(2)(c), to be 4.96 0.30(stat. + syst.) zE 0.30(lumi.) pb, in agreement with the Standard Model prediction of 4.74 0.22 pb. This is the most precise Zy cross section measurement at a hadron col…

Coronary Spasm in Patients Treated by Percutaneous Transluminal Coronary Angioplasty

The appearance of coronary spasm during PTCA was analyzed in 140 consecutive patients with stable and unstable angina. Coronary spasm was found in 27 patients (19%) and was more common in unstable than in stable angina pectoris (22 versus 5 patients). While coronary spasm could be seen in the first coronary angiogram in 5/27 patients, it developed during the diagnostic procedure in 6/27 patients. In 16/27 patients coronary spasm was induced by the balloon or the guide wire itself.

Search for flavor-changing-neutral-current D meson decays

We study the flavor-changing-neutral-current process c to u mu+ mu- using 1.3 fb^-1 of p p bar collisions at sqrt(s) = 1.96 TeV recorded by the D0 detector operating at the Fermilab Tevatron Collider. We see clear indications of the Ds+ and D+ to phi pi+ to mu+ mu- pi+ final states with significance greater than four standard deviations above background for the D+ state. We search for the continuum decay of D+ to pi+mu+mu- in the dimuon invariant mass spectrum away from the phi resonance. We see no evidence of signal above background and set a limit of B(D+ to pi+mu+mu-) &lt; 3.9 x 10^-6 at the 90% C.L. This limit places the most stringent constraint on new phenomena in the c to u mu+ mu- t…

Study of heavy-flavor quarks produced in association with top-quark pairs at s=7  TeV using the ATLAS detector

Using a sample of dilepton top-quark pair ((tt) over bar) candidate events, a study is performed of the production of top-quark pairs together with heavy-flavor (HF) quarks, the sum of (tt) over bar + b + X and (tt) over bar + c + X, collectively referred to as (tt) over bar + HF. The data set used corresponds to an integrated luminosity of 4.7 fb(-1) of proton-proton collisions at a center-of-mass energy of 7 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. The presence of additional HF (b or c) quarks in the (tt) over bar sample is inferred by looking for events with at least three b-tagged jets, where two are attributed to the b quarks from the (tt) over bar decays a…

Angiographic follow-up results of a randomized study on angioplasty versus bypass surgery (GABI Trial)

Although several randomized trials have been performed to compare the outcomes of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass surgery (CABG) in patients with multivessel disease, there is little data available on angiographic follow-up results. The present substudy of the German angioplasty versus bypass surgery investigation (GABI Trial) compares the angiographic revascularization status in these two cases 6 months after treatment. Follow-up angiograms were available in 102 CABG patients and 117 PTCA patients. Although the protocol excluded patients with total occlusion, on follow-up 6 months after treatment we found total occlusion of 94 native arterie…

Search for anomalous production of prompt like-sign muon pairs and constraints on physics beyond the Standard Model with the ATLAS detector

An inclusive search for anomalous production of two prompt, isolated muons with the same electric charge is presented. The search is performed in a data sample corresponding to 1.6  fb−1 of integrated luminosity collected in 2011 at √s=7  TeV with the ATLAS detector at the LHC. Muon pairs are selected by requiring two isolated muons of the same electric charge with pT>20  GeV and |η|<2.5. Minimal requirements are placed on the rest of the event activity. The distribution of the invariant mass of the muon pair m(μμ) is found to agree well with the background expectation. Upper limits on the cross section for anomalous production of two muons with the same electric charge are placed as a func…

Search for long-lived, heavy particles in final states with a muon and multi-track displaced vertex in proton–proton collisions at s=7 TeV with the ATLAS detector

Many extensions of the Standard Model posit the existence of heavy particles with long lifetimes. In this Letter, results are presented of a search for events containing one or more such particles, which decay at a significant distance from their production point, using a final state containing charged hadrons and an associated muon. This analysis uses a data sample of proton-proton collisions at root s = 7 TeV corresponding to an integrated luminosity of 4.4 fb(-1) collected in 2011 by the ATLAS detector operating at the Large Hadron Collider. Results are interpreted in the context of R-parity violating supersymmetric scenarios. No events in the signal region are observed and limits are se…

Clinical and morphological characteristics in Streptococcus bovis endocarditis: a comparison with other causative microorganisms in 177 cases

Aim—To compare the clinical and morphological characteristics of patients with Streptococcus bovis endocarditis with those of patients with endocarditis caused by other microorganisms. Methods—177 consecutive patients (Streptococcus bovis, 22; other streptococci, 94; staphylococci, 44; other, 17) with definite infective endocarditis according to the Duke criteria were included. All patients underwent transthoracic and transoesophageal echocardiography. In 88 patients, findings from surgery/necropsy were obtained. Results—S bovis endocarditis was associated with older patients, with a higher mortality (p = 0.04), and with a higher rate of cardiac surgery (p < 0.001) than other microorganisms…

Interventional cardiology: Differences in the morphology of unstable and stable coronary lesions and their impact on the mechanisms of angioplasty. An in vivo study with intravascular ultrasound

The aim of this study was to compare the morphology of stable and unstable coronary lesions using intravascular ultrasound in patients undergoing coronary balloon angioplasty and to determine whether lesion morphology had any influence on the mechanism of balloon angioplasty. Thirty three (15 stable and 18 unstable) patients undergoing single lesion percutaneous transluminal coronary angioplasty were studied with intravascular ultrasound before and after intervention. All examinations, recorded on S-VHS video tape, were studied off-line and matched sites from the point of minimum lumen area after the procedure and the corresponding site prior to intervention were compared. The morphology of…

Search for FCNC single top-quark production at s=7 TeV with the ATLAS detector

A search for the production of single top-quarks via flavour-changing neutral-currents is presented. Data collected with the ATLAS detector at a centre-of-mass energy of root s = 7 TeV, correspondi ...

Search for R-parity violating supersymmetry via the LLE¯ couplings λ121, λ122 or λ133 in pp¯ collisions at s=1.96 TeV

A search for gaugino pair production with a trilepton signature in the framework of R-parity violating supersymmetry via the couplings lambda_121, lambda_122, or lambda_133 is presented. The data, corresponding to an integrated luminosity of L~360/pb, were collected from April 2002 to August 2004 with the D0 detector at the Fermilab Tevatron Collider, at a center-of-mass energy of sqrt(s)=1.96 TeV. This analysis considers final states with three charged leptons with the flavor combinations eel, mumul, and eetau (l=e or mu). No evidence for supersymmetry is found and limits at the 95% confidence level are set on the gaugino pair production cross section and lower bounds on the masses of the …

Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of √s = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of Ks and Λ particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncert…

Comparison of Statistical Methods for the Detection of Contrast Material in Echocardiographic Image Sequences

Ultrasonic imaging of the heart is a diagnostic tool which is increasingly used in cardiology. In addition to the representation of important anatomical information two dimensional images provided by mechanical or electronically steered sector scanners can be used for the extraction of functional parameters of the heart (as e.g. enddiastolic volume or ejection fraction). A poor definition of the endocardial border especially resulting from the noisy appearance of the images and from qualitatively restricted echocardiograms leads to uncertainties in the quantitative analysis and therefore requires refined methods for the determination of functional parameters. Our investigations which are ba…

Aortic dissection detected by transoesophageal echocardiography

The diagnostic value of transoesophageal echocardiography was evaluated in 24 patients with aortic dissection and compared to transthoracic two-dimensional echocardiography, computer tomography, aortography, surgery and autopsy. Using transoesophageal echocardiography we found in 5 patients a type I dissection, in 5 patients a type II and in 14 patients a type III dissection. Transthoracic two-dimensional echocardiography was positive in 3/5 type I, 2/5 in type II and 2/14 in type III dissections. Computer tomography was unable to demonstrate an intimal flap in 1/2 patients with type I, 2/3 type II and 1/11 type III dissections. Aortography was negative in 1/4 type I, 3/5 type II and 3/12 p…

The effect of balloon dilatation on post-stenotic myocardial perfusion before and after stimulation of coronary flow reserve: evaluation by the densitometric parameter 'mean rise time'.

From densitometric evaluation of digital subtraction cineangiocardiograms the parameter 'Mean Rise Time' (MRT), defined as the time from the onset of local myocardial contrast medium opacification to the point of maximal opacification can be derived; this parameter revealed a close correlation with the results on myocardial perfusion obtained by Thallium-201 scintigraphy. A prolonged 'Mean Rise Time' was indicative of an impairment of myocardial perfusion. We have developed a heart-phase gated real-time digitization procedure and computer-supported method for the densitometric estimation of the MRT to obtain information about the effect of coronary balloon dilatation on myocardial perfusion…

The ATLAS Inner Detector commissioning and calibration

The ATLAS Inner Detector is a composite tracking system consisting of silicon pixels, silicon strips and straw tubes in a 2 T magnetic field. Its installation was completed in August 2008 and the detector took part in data-taking with single LHC beams and cosmic rays. The initial detector operation, hardware commissioning and insitu calibrations are described. Tracking performance has been measured with 7.6 million cosmic-ray events, collected using a tracking trigger and reconstructed with modular pattern-recognition and fitting software. The intrinsic hit efficiency and tracking trigger efficiencies are close to 100%. Lorentz angle measurements for both electrons and holes, specific energ…

Prognostic significance of repetitive ventricular response in chronic coronary artery disease.

A prospective study was conducted in 267 patients with angiographically defined coronary artery disease without documented ventricular tachycardia to determine the prognostic significance of repetitive ventricular response (RVR) after programmed electrical stimulation (PES). The patients were classified inducible if RVR with 3 or more echo beats (RVR greater than or equal to 3) could be induced. 89 patients without previous myocardial infarction (MI), 61 survivors of MI occurring between 6 weeks and 3 months before and 117 patients who had survived longer than 3 months after MI were studied. A standardized stimulation protocol with single (S1S2) and double (S1S2S3) extrastimuli during ventr…

Measurement of the centrality dependence of J/ψ yields and observation of Z production in lead–lead collisions with the ATLAS detector at the LHC

Using the ATLAS detector, a centrality-dependent suppression has been observed in the yield of J/psi mesons produced in the collisions of lead ions at the Large Hadron Collider. In a sample of minimum-bias lead-lead collisions at a nucleon-nucleon centre of mass energy root s(NN) = 2.76 TeV, corresponding to an integrated luminosity of about 6.7 mu b(-1), J/psi mesons are reconstructed via their decays to mu(+)mu(-) pairs. The measured J/psi yield, normalized to the number of binary nucleon-nucleon collisions, is found to significantly decrease from peripheral to central collisions. The centrality dependence is found to be qualitatively similar to the trends observed at previous, lower ener…

Search for massive long-lived highly ionising particles with the ATLAS detector at the LHC

A search is made for massive highly ionising particles with lifetimes in excess of 100 ns, with the ATLAS experiment at the Large Hadron Collider, using 3.1 pb-1 of pp collision data taken at √s = 7TeV. The signature of energy loss in the ATLAS inner detector and electromagnetic calorimeter is used. No such particles are found and limits on the production cross section for electric charges 6e ≤ |q| ≤ 17e and masses 200 GeV ≤ m ≤ 1000 GeV are set in the range 1–12 pb for different hypotheses on the production mechanism.

Microphysical properties of synoptic scale polar stratospheric clouds: in situ measurements of unexpectedly large HNO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; containing particles in the Arctic vortex

Abstract. In January 2010 and December 2011 synoptic scale PSC fields were probed during seven flights of the high altitude research aircraft M-55 Geophysica within the RECONCILE (Reconciliation of essential process parameters for an enhanced predictability of Arctic stratospheric ozone loss and its climate interaction.) and the ESSenCe (ESSenCe: ESA Sounder Campaign) projects. Particle size distributions in a diameter range between 0.46 μm and 40 μm were recorded simultaneously by up to four different optical in situ instruments. Three of these particle instruments are based on the detection of forward scattered light by single particles. The fourth instrument is a grey scale optical array…

Intraluminal Doppler-Sonography: Analysis and “in Vitro Test” of a New Device

In treating patients with coronary heart disease it’ s necessary first to determine what influence the stenose has on the coronary blood flow. This is a prerequisite for any invasive treatment method. Coronary angiography explosures are only partially useful in attaining a functional evaluation of the haemodynamic stenoses.

Search for Down-Type Fourth Generation Quarks with the ATLAS Detector in Events with One Lepton and Hadronically Decaying W Bosons

This Letter presents a search for pair production of heavy down-type quarks decaying via b′→Wt in the lepton+jets channel, as b′¯b′→W−tW+¯t→b¯bW+W−W+W−→l±νb¯bq¯qq¯qq¯q. In addition to requiring exactly one lepton, large missing transverse momentum, and at least six jets, the invariant mass of nearby jet pairs is used to identify high transverse momentum W bosons. In data corresponding to an integrated luminosity of 1.04  fb−1 from pp collisions at √s=7  TeV recorded with the ATLAS detector, a heavy down-type quark with mass less than 480 GeV can be excluded at the 95% confidence level.

Measurement of photon?jet transverse momentum correlations in 5.02 TeV Pb + Pb and pp collisions with ATLAS

Jets created in association with a photon can be used as a calibrated probe to study energy loss in the medium created in nuclear collisions. Measurements of the transverse momentum balance between isolated photons and inclusive jets are presented using integrated luminosities of 0.49 nb−1 of Pb + Pb collision data at TeV and 25 pb−1 of pp collision data at TeV recorded with the ATLAS detector at the LHC. Photons with transverse momentum GeV and are paired with all jets in the event that have GeV and pseudorapidity . The transverse momentum balance given by the jet-to-photon ratio, , is measured for pairs with azimuthal opening angle . Distributions of the per-photon jet yield as a function…

Measurement of the ratio of the pp¯→W+c-jet cross section to the inclusive pp¯→W+jets cross section

We present a measurement of the fraction of inclusive W +jets events produced with net charm quantum number 11, denoted W + c-jet, in p collisions at root s = 1.96 TeV using approximately 1 fb(-1) of data collected by the DO detector at the Fermilab Tevatron Collider. We identify the W +jets events via the leptonic W boson decays. Candidate W + c-jet events are selected by requiring a jet containing a muon in association with a reconstructed W boson and exploiting the charge correlation between this muon and W boson decay lepton to perform a nearly model-independent background subtraction. We measure the fraction of W + c-jet events in the inclusive W +jets sample for jet PT > 20 GeV and ps…

Search for dark matter in events with heavy quarks and missing transverse momentum in [Formula: see text] collisions with the ATLAS detector.

This article reports on a search for dark matter pair production in association with bottom or top quarks in \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$20.3 \mathrm {~fb}^{-1}$$\end{document}20.3fb-1 of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$pp$$\end{document}pp collisions collected at \documentclass[12pt]{minimal} \use…

A plea for provisional stenting.

Quantitative versus qualitative Beurteilung der linksventrikulären Funktion — Praktikabilität und Limitationen

Die Prognose des Patienten mit koronarer Herzkrankheit ist entscheidend von den Volumina des linken Herzens und der Ejektionsfraktion abhangig (17, 32). Ein nichtinvasiver Zugang zu diesen Parametern ist daher fur die Risikostratifizierung und Verlaufsbeurteilung unter Therapie von grosem klinischen Wert. Einen solchen Zugang bietet die zweidimensionale Echokardiographie. Seit ihrer Einfuhrung in die Klinik Ende der siebziger Jahre besteht jedoch eine noch immer andauernde Auseinandersetzung uber die Frage, ob es moglich ist, eine exakte Quantifizierung der linksventrikularen Funktion mittels zweidimensionaler Echokardiographie vorzunehmen, oder ob nur eine mehr qualitative Beurteilung mogl…

Diagnostic value of transesophageal echocardiography in patients with coronary artery disease and mitral insufficiency

Any diagnosis of mitral regurgitation must always include the etiology. The clinical history is only rarely informative, as are chest x-ray examinations. The ECG is of value to diagnose coronary artery disease with or without previous myocardial infarction — but further differentiation is not possible. During heart catheterization mitral insufficiency can be diagnosed and quantified according to Seller’s classification [1]. A differentiation of etiology is only rarely possible. Rheumatic heart disease and mitral valve prolapse can be differentiated.

Search for decays of stopped, long-lived particles from 7 TeV pp collisions with the ATLAS detector

New metastable massive particles with electric and colour charge are features of many theories beyond the Standard Model. A search is performed for long-lived gluino-based R-hadrons with the ATLAS detector at the LHC using a data sample corresponding to an integrated luminosity of 31 pb[superscript −1]. We search for evidence of particles that have come to rest in the ATLAS detector and decay at some later time during the periods in the LHC bunch structure without proton–proton collisions. No significant deviations from the expected backgrounds are observed, and a cross-section limit is set. It can be interpreted as excluding gluino-based R-hadrons with masses less than 341 GeV at the 95 % …

Measurement of D⁎±, D± and Ds± meson production cross sections in pp collisions at s=7 TeV with the ATLAS detector

The production of D*(+/-), D-+/- and D-S(+/-) charmed mesons has been measured with the ATLAS detector in pp collisions at,/7s = 7 TeV at the LHC, using data corresponding to an integrated luminosi ...

Measurement of the production cross section for W-bosons in association with jets in pp collisions at s=7 TeV with the ATLAS detector

This Letter reports on a first measurement of the inclusive W + jets cross section in proton-proton collisions at a centre-of-mass energy of 7 TeV at the LHC, with the ATLAS detector. Cross section ...

Search for events with large missing transverse momentum, jets, and at least two tau leptons in 7 TeV proton–proton collision data with the ATLAS detector

A search for events with large missing transverse momentum, jets, and at least two tau leptons has been performed using 2 fb[superscript −1] of proton–proton collision data at √s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectation is observed and a 95% CL upper limit on the visible cross section for new phenomena is set, where the visible cross section is defined by the product of cross section, branching fraction, detector acceptance and event selection efficiency. A 95% CL lower limit of 32 TeV is set on the gauge-mediated supersymmetry breaking (GMSB) scale Λ independent of tan β. These limits provide the most s…

Klinische Pharmakologie I

Rifampicin (RMP) induziert nach mehrtagiger Gabe die mischfunktionellen Oxygenasen in der Leber, so das auch sein eigener Metabolismus beschleunigt wird (Eigeninduktion, Acocella 1978a). Wie wir beobachteten, nahmen die RMP-Plasmaspiegel unter oraler Dauertherapie starker ab als bei intravenoser Applikation (Musch et al. 1982; Loos et al. 1983). Klinisch zeigten 30 initial mit RMP intravenos behandelte Patienten mit offener Lungentuberkulose eine schnellere Sputumnegativierung und Rontgenbefundbesserung im Vergleich zu 48 oral therapierten Patienten (Kombinationstherapie: RMP-Isoniazid-Ethambutol). So war z. B. die Sputumkulturkonversion nach dem 1. Behandlungsmonat bei intravenoser RMP-Gab…

New techniques for visualization of losses due to image compression in grayscale medical still images

To evaluate the visual influence of irreversible compression on medical images, changes of the images have to be visualized. The authors have explored alternative techniques to be used instead of the usual side-by-side comparison, where the information contained in both images is perceived in a single image, preserving the context between compression errors and image structures. Thus fast and easy comparison can be done. These techniques make use of the human ability to perceive information also in the dimensions of color, space, and time. A study was performed with JPEG-compressed coronary angiographic images. Changes in the resulting images for six compression factors from 7 to 30 were sc…

Search for supersymmetry in di-photon final states at s=1.96 TeV

We report results of a search for supersymmetry (SUSY) with gauge-mediated symmetry breaking in di-photon events collected by the DO experiment at the Fermilab Tevatron Collider in 2002-2006. In 1.1 fb(-1) of data, we find no significant excess beyond the background expected from the standard model and set the most stringent lower limits to date for a standard benchmark model on the lightest neutralino and chargino masses of 125 GeV and 229 GeV, respectively, at 95% confidence.

Comparison of myocardial perfusion reserve before and after coronary balloon predilatation and after stent implantation in patients with postangioplasty restenosis.

Background Stents provide a scaffold for coronary arteries after angioplasty and inhibit elastic recoil. Methods and Results In 25 patients with postangioplasty restenosis of the left anterior descending artery, ECG-gated digital subtraction coronary angiograms were recorded at baseline and during hyperemia (12 mg papaverine IC) before and after balloon predilatation (PTCA), after implantation of a Palmaz-Schatz stent, and after 6 months. Densitometric evaluation revealed different time and density parameters to calculate two definitions of myocardial perfusion reserve (MPR1 and MPR2) and maximum flow ratio (MaxFR). Poststenotic MPR1 increased from 1.57±0.14 to 2.59±0.86 after PTCA and to …

Recanalization of Totally Occluded Coronary Vessels by Percutaneous Transluminal Coronary Angioplasty

Since its introduction in 1977, percutaneous transluminal coronary angioplasty (PTCA) has become an effective approach for treatment of patients with single-vessel disease [1–3, 5]. Treatment of double- and multiple-vessel disease has also been attempted [5, 6]. In patients with angina pectoris total occlusion of coronary vessels is found, and PTCA has also been used in an attempt to restore coronary blood flow in such patients [8, 10]. Even main stem occlusions have been recanalized [11]. In patients with total occlusion of coronary vessels, collateral flow is sufficient to maintain cardiac function at rest but not during exercise [12–14]. Therefore, PTCA seems to be an ideal method for re…

Search for particles decaying into a Z boson and a photon in pp¯ collisions at s=1.96 TeV

Abstract We present the results of a search for a new particle X produced in p p ¯ collisions at s = 1.96 TeV and subsequently decaying to Zγ. The search uses 0.3 fb−1 of data collected with the DO detector at the Fermilab Tevatron Collider. We set limits on the production cross section times the branching fraction σ ( p p ¯ → X ) × B ( X → Z γ ) that range from 0.4 to 3.5 pb at the 95% C.L. for X with invariant masses between 100 and 1000 GeV / c 2 , over a wide range of X decay widths.

High frequency rotational ablation: an alternative in treating coronary artery stenoses and occlusions.

OBJECTIVE--To prove the safety and effectiveness of high frequency rotational ablation of coronary artery stenoses and occlusion in humans. SUBJECTS--106 patients with symptoms (91 men, 15 women) who had 67 significant stenoses, mainly types B and C, and 46-chronic occlusions. MAIN OUTCOME MEASURES--Mean change in diameter stenosis after rotational angioplasty alone and in combination with percutaneous transluminal coronary angioplasty immediately after treatment and 24 hours and six months later; restenosis rates at six months; complication of treatment. RESULTS--Rotational ablation could not be used in five stenoses and 16 chronic occlusions because of inability to reach or cross the lesi…

Search for Diphoton Events with Large Missing Transverse Energy with 36 pb^-1 of 7 TeV Proton-Proton Collision Data with the ATLAS Detector

Making use of 36 pb^-1 of proton-proton collision data at sqrt{s} = 7 TeV, the ATLAS Collaboration has performed a search for diphoton events with large missing transverse energy. Observing no excess of events above the Standard Model prediction, a 95% Confidence Level (CL) upper limit is set on the cross section for new physics of sigma &lt; 0.38 - 0.65 pb in the context of a generalised model of gauge mediated supersymmetry breaking (GGM) with a bino-like lightest neutralino, and of sigma &lt; 0.18 - 0.23 pb in the context of a specific model with one universal extra dimension (UED). A 95 % CL lower limit of 560 GeV, for bino masses above 50 GeV, is set on the GGM gluino mass, while a low…

Measurement of the distributions of event-by-event flow harmonics in lead-lead collisions at = 2.76 TeV with the ATLAS detector at the LHC

We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portu…

Erratum to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC‑GLOSSARI): a multicenter, multinational, 14-day inception cohort study (Intensive Care Medicine, (2016), 42, 5, (953), 10.1007/s00134-016-4317-4)

In both the original publication (DOI 10.1007/s00134-015-4206-2) and the first erratum (DOI 10.1007/s00134-016-4317-4), the members of the IC-GLOSSARI Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for these errors and is pleased to list the members of the groups here: (Table presented.).

Detection of spontaneous echocardiographic contrast within the left atrium by transesophageal echocardiography: spontaneous echocardiographic contrast

Transesophageal echocardiography was performed in 314 patients over a period of 24 months using a 3.5 MHz phased-array system fitted to the distal end of a conventional 12 mm endoscope. In 12 patients (2.6%) transesophageal echocardiography could not be performed because of adverse reaction to the gastroscopic procedure. Side effects were a transient A-V block in one patient and asthmatic attack in another. Mitral valve lesions were found in 99 of 314 patients. In 9 of these 99 patients (11%), including 1 patient with mitral valve stenosis and sinus rhythm, 2 with atrial fibrillation, 3 with disc, and 3 with porcine mitral prosthesis, spontaneous echocardiographic contrast was found within …

Measurement of Wγ and Zγ production in proton-proton collisions at √s =7 TeV with the ATLAS detector

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

Parametric assessment of myocardial perfusion during interventional cardiac catheterization by means of X-ray densitometry-short-and long-term results.

X-ray densitometric evaluation of digital subtraction angiocardiograms allows an assessment of myocardial perfusion by means of the parameter 'MEAN RISE TIME' (MRT), defined as the time from the onset of local myocardial contrast medium opacification to the point of maximum opacification. Best results are obtained when the response of that parameter is compared before and after stimulation of coronary flow by papaverine. A prolongation of this parameter, especially after papaverine, was indicative of an impairment of myocardial perfusion, when compared to the results of TL-201 scintigraphy. In 50 patients with single vessel coronary artery disease the results of MRT pre and post papaverine …

Intraluminal Doppler-sonography: a new device for data analysis and its in vitro test

Summary form only given. A special data acquisition unit has been developed which allows to process on-line not only the mean-phasic Doppler shift signal but also to analyze the spectral contents and the received A-mode signal. The probe consists of a 3f-catheter which is activated by a pulsed transmitter-receiver (Millar). The carrier frequency is 20 MHz and the impulse repetition rate is 62.5 kHz. Two modular A/D converters are used. One digitizes directly the Doppler shift frequencies in the range less than 20 kHz (sampling rate 100 kHz, resolution 12 bit); the other digitizes the RF-signal (sampling rate 200 MHz, resolution 8 bit). For further processing, data are transferred via separa…

Arrhythmieprofil und Herzfrequenz bei Hyperthyreose

Arrhythmia profiles and heart rates, obtained by 24-hour ECG monitoring, were analysed in 48 patients with hyperthyroidism before (T3 level: 331 +/- 108 ng/100 ml, heart rate: 95 +/- 13/min), during (T3 level: 202 +/- 98 ng/100 ml, heart rate: 85 +/- 11/min) and after (T3 level: 149 +/- 41 ng/100 ml, heart rate: 79 +/- 9/min) antithyroid treatment. 50 persons in whom organic heart disease has been excluded by invasive and noninvasive tests served as controls. Only 6% of patients had repetitive ventricular arrhythmias (Lown group IV) before treatment (controls: 4%; P greater than 0.05). Supraventricular extrasystoles were common both before and after treatment (P less than 0.001), especially…

Intravascular ultrasound detected classification of coronary lesions as a predictor of dissections after balloon angioplasty.

Dissection after balloon angioplasty of coronary arteries may give rise to an unfavourable early outcome. Compared with coronary angiography, intravascular ultrasound (IVUS) allows more detailed characterisation of dissections. We investigated the incidence and type of dissections after balloon angioplasty in calcified coronary lesions. IVUS was performed in 43 patients with 48 lesions before and after percutaneous balloon angioplasty. Significant calcification was defined as an arc of more than 90 degrees with typical acoustic shadowing. Dissections were classified as type A when the media was not involved by the dissection and as type B when media involvement had occurred. In the group wi…

A combined search for the standard model Higgs boson at s=1.96 TeV

AbstractWe present new results of the search for WH→ℓνbb¯ production in pp¯ collisions at a center-of-mass energy of s=1.96 TeV, based on a dataset with integrated luminosity of 0.44 fb−1. We combine these new results with previously published searches by the D0 collaboration, for WH and ZH production analyzed in the E̸Tbb¯ final state, for ZH (→ℓ+ℓ−bb¯) production, for WH (→WWW) production, and for H (→WW) direct production. No signal-like excess is observed either in the WH analysis or in the combination of all D0 Higgs boson analyses. We set 95% C.L. (expected) upper limits on σ(pp¯→WH)×B(H→bb¯) ranging from 1.6 (2.2) pb to 1.9 (3.3) pb for Higgs boson masses between 105 and 145 GeV, to …

Evidence for the spin-0 nature of the Higgs boson using ATLAS data

We acknowledge the support of ANPCyT, Argentina; YerPhl, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portu…

Search for squarks and gluinos using final states with jets and missing transverse momentum with the ATLAS detector in s=7 TeV proton–proton collisions

A search for squarks and gluinos in events containing jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2011 by the ATLAS experiment in root s = 7 TeV proton-proton collisions at the Large Hadron Collider. No excess above the Standard Model background expectation is observed in 1.04 fb(-1) of data. Gluino and squark masses below 700 GeV and 875 GeV respectively are excluded at the 95% confidence level in simplified models containing only squarks of the first two generations, a gluino octet and a massless neutralino. The exclusion limit increases to 1075 GeV for squarks and gluinos of equal mass. In MSUGRA/CMSSM models with tan beta = 10, A(0…

Measurement of dijet production with a veto on additional central jet activity in pp collisions at sqrt(s)=7 TeV using the ATLAS detector

A measurement of jet activity in the rapidity interval bounded by a dijet system is presented. Events are vetoed if a jet with transverse momentum greater than 20 GeV is found between the two boundary jets. The fraction of dijet events that survive the jet veto is presented for boundary jets that are separated by up to six units of rapidity and with mean transverse momentum 50 < p¯T < 500 GeV. The mean multiplicity of jets above the veto scale in the rapidity interval bounded by the dijet system is also presented as an alternative method for quantifying perturbative QCD emission. The data are compared to a next-to-leading order plus parton shower prediction from the powheg-box, an all-order…

A search for new physics in dijet mass and angular distributions in pp collisions at [subscript √s=7] TeV measured with the ATLAS detector

A search for new interactions and resonances produced in LHC proton–proton (pp) collisions at a centre-of-mass energy ps = 7 TeV was performed with the ATLAS detector. Using a dataset with an integrated luminosity of 36 pb−1, dijet mass and angular distributions were measured up to dijet masses of 3.5 TeV and were found to be in good agreement with Standard Model predictions. This analysis sets limits at 95% CL on various models for new physics: an excited quark is excluded for mass between 0.60 and 2.64 TeV, an axigluon hypothesis is excluded for axigluon masses between 0.60 and 2.10 TeV and quantum black holes are excluded in models with six extra space–time dimensions for quantum gravity…

Commissioning of the ATLAS Muon Spectrometer with cosmic rays

The ATLAS detector at the Large Hadron Collider has collected several hundred million cosmic ray events during 2008 and 2009. These data were used to commission the Muon Spectrometer and to study the performance of the trigger and tracking chambers, their alignment, the detector control system, the data acquisition and the analysis programs. We present the performance in the relevant parameters that determine the quality of the muon measurement. We discuss the single element efficiency, resolution and noise rates, the calibration method of the detector response and of the alignment system, the track reconstruction efficiency and the momentum measurement. The results show that the detector i…

New balloon catheter for prolonged percutaneous transluminal coronary angioplasty and bypass flow in occluded vessels.

A new balloon catheter was developed for continuous perfusion of coronary arteries during angioplasty (CPC catheter). Steerable Gruntzig balloon catheters (3.7 mm) with two lumina were formed. The first lumen was used for balloon inflation. Side holes to the second lumen proximally and distally to the balloon were created for coronary perfusion even during inflation phase. At a perfusion pressure of 120 mmHg, a flow rate of 63 +/- 3 ml/min with 0.9% saline and 43 +/- 1 ml/min with plasma expander were measured. In experiments on five dogs, dilation time until appearance of signs of ischemia could be prolonged in three of five dogs from 30 to 40 s, 120 to 203 s, and 180 to 420 s comparing co…

Readiness of the ATLAS liquid argon calorimeter for LHC collisions

The ATLAS liquid argon calorimeter has been operating continuously since August 2006. At this time, only part of the calorimeter was readout, but since the beginning of 2008, all calorimeter cells have been connected to the ATLAS readout system in preparation for LHC collisions. This paper gives an overview of the liquid argon calorimeter performance measured in situ with random triggers, calibration data, cosmic muons, and LHC beam splash events. Results on the detector operation, timing perfor-mance, electronics noise, and gain stability are presented. High energy deposits from radiative cosmic muons and beam splash events allow to check the intrinsic constant term of the energy resolutio…

Search for second generation scalar leptoquarks in $pp$ collisions at $\sqrt{s}=7$ TeV with the ATLAS detector

The results of a search for the production of second generation scalar leptoquarks are presented for final states consisting of either two muons and at least two jets or a muon plus missing transverse momentum and at least two jets. A total of 1.03 fb−1 integrated luminosity of proton-proton collision data produced by the Large Hadron Collider at \(\sqrt{s}=7~\mbox{TeV}\) and recorded by the ATLAS detector is used for the search. The event yields in the signal regions are found to be consistent with the Standard Model background expectations. The production of second generation leptoquarks is excluded for a leptoquark mass mLQ<594 (685) GeV at 95 % confidence level, for a branching ratio of…

Assessment of left ventricular function during aortic balloon valvuloplasty by transesophageal echocardiography

Several reports have documented the feasability and utility of balloon aortic valvuloplasty as a palliative treatment for high-surgical-risk patients with critical aortic valve stenosis (1–3).

Measurement of the inclusive isolated prompt photon cross-section in pp collisions at s=7 TeV using 35 pb−1 of ATLAS data

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy root s = 7 TeV is presented. The measurement cove ...

Intermittierende Fieberschübe Lyme-Erkrankung ohne Erythema chronicum migrans

Factors controlling plankton community production, export flux, and particulate matter stoichiometry in the coastal upwelling system off Peru

Eastern boundary upwelling systems (EBUS) are among the most productive marine ecosystems on Earth. The production of organic material is fueled by upwelling of nutrient-rich deep waters and high incident light at the sea surface. However, biotic and abiotic factors can modify surface production and related biogeochemical processes. Determining these factors is important because EBUS are considered hotspots of climate change, and reliable predictions of their future functioning requires understanding of the mechanisms driving the biogeochemical cycles therein. In this field experiment, we used in situ mesocosms as tools to improve our mechanistic understanding of processes controlling organ…

New bundle branch block after coronary artery bypass grafting— evaluation by CK-MB isoenzyme analysis and transoesophageal echocardiography

Twelve patients with a new complete bundle branch block after coronary artery bypass grafting underwent transoesophageal echocardiography (TEE). The results of TEE were compared with the pre-operative ventriculography, CK-MB isoenzyme time-release curves and clinical course. In eight patients with transient right bundle branch block or bifascicular block, low CK-MB activities and an uncomplicated postoperative course, transoesophageal echocardiography showed no new segmental wall motion abnormalities apart from a paradoxical septal movement in five. A persistent right or left bundle branch block was associated with either elevated isoenzyme activities, transoesophageal echocardiographic evi…

Search for tt¯ resonances in the lepton plus jets final state in pp¯ collisions at s=1.96TeV

We present a search for a narrow-width heavy resonance decaying into top quark pairs X->ttbar in ppbar collisions at sqrt{s}=1.96TeV using approximately 0.9fb^-1 of data collected with the D0 detector at the Fermilab Tevatron Collider. This analysis considers ttbar candidate events in the lepton plus jets channel with at least one identified b jet and uses the ttbar invariant mass distribution to search for evidence of resonant production. We find no evidence for a narrow resonance X decaying to ttbar. Therefore, we set upper limits on sigma*B(X->ttbar) for different hypothesized resonance masses using a Bayesian approach. For a Topcolor-assisted technicolor model, the existence of a leptop…

Model-independent measurement of the W-boson helicity in top-quark decays at D0.

Made available in DSpace on 2022-04-28T20:37:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-14 Science and Technology Facilities Council We present the first model-independent measurement of the helicity of W bosons produced in top quark decays, based on a 1fb-1 sample of candidate tt̄ events in the dilepton and lepton plus jets channels collected by the D0 detector at the Fermilab Tevatron pp̄ Collider. We reconstruct the angle θ* between the momenta of the down-type fermion and the top quark in the W boson rest frame for each top quark decay. A fit of the resulting cos θ* distribution finds that the fraction of longitudinal W bosons f0=0.425±0.166(stat)±0.102(syst) and the f…

Measurement of W ± Z production in proton-proton collisions at √s =7 TeV with the ATLAS detector

A study of W±Z production in proton-proton collisions at √s=7 TeV is presented using data corresponding to an integrated luminosity of 4.6 fb−1 collected with the ATLAS detector at the Large Hadron Collider in 2011. In total, 317 candidates, with a background expectation of 68±10 events, are observed in double-leptonic decay final states with electrons, muons and missing transverse momentum. The total cross-section is determined to be σtotWZ=19.0+1.4−1.3(stat.)±0.9(syst.)±0.4(lumi.) pb, consistent with the Standard Model expectation of 17.6+1.1−1.0 pb. Limits on anomalous triple gauge boson couplings are derived using the transverse momentum spectrum of Z bosons in the selected events. The …

Search for long-lived, multi-charged particles in pp collisions at s=7 TeV using the ATLAS detector

A search for highly ionising, penetrating particles with electric charges from |q| = 2e to 6e is performed using the ATLAS detector at the CERN Large Hadron Collider. Proton-proton collision data taken at sqrt(s)=7 TeV during the 2011 running period, corresponding to an integrated luminosity of 4.4 fb^-1, are analysed. No signal candidates are observed, and 95% confidence level cross-section upper limits are interpreted as mass-exclusion lower limits for a simplified Drell--Yan production model. In this model, masses are excluded from 50 GeV up to 430, 480, 490, 470 and 420 GeV for charges 2e, 3e, 4e, 5e and 6e, respectively.

Use of transoesophageal echocardiography in the diagnosis of abscess in infective endocarditis

Transoesophageal echocardiography is invaluable clinically since it accurately images abscess cavities or aneurysms. It provides the information about the site and extension of abscesses which is needed by surgeons to time and define surgical intervention. Early diagnosis is advantageous, and abscesses should be expected in 5%-30% of patients with echocardiographically discernible vegetations. Since there is no 'abscess typical' organism, transoesophageal echocardiographic examination is helpful at the first indication of infective endocarditis, to identify high-risk patients. Involvement of the aortic valve, growth in the size of vegetations, and the presence of spontaneous echo contrast a…

Search for diphoton events with large missing transverse momentum in 7 TeV proton-proton collision data with the ATLAS detector

A search for diphoton events with large missing transverse momentum has been performed using proton–proton collision data at √s = 7 TeV recorded with the ATLAS detector, corresponding to an integrated luminosity of 4.8 fb[superscript −1]. No excess of events was observed above the Standard Model prediction and model-dependent 95% confidence level exclusion limits are set. In the context of a generalised model of gauge-mediated supersymmetry breaking with a bino-like lightest neutralino of mass above 50 GeV, gluinos (squarks) below 1.07 TeV (0.87 TeV) are excluded, while a breaking scale Λ below 196 TeV is excluded for a minimal model of gauge-mediated supersymmetry breaking. For a specific …

Die akute Gefäßperforation mit Shuntbildung in den rechten Ventrikel nach perkutaner transluminaler Koronarangioplastie. Kernspintomographischer und dopplersonographischer Nachweis des Shuntflusses

Die Gefasperforation nach transluminaler Koronarangioplastie (PTCA) stellt eine seltene Komplikation dieser etablierten Behandlungsmethode dar. Die Therapie wird bestimmt durch die hamodynamische Beeintrachtigung des linken oder rechten Ventrikels. Wir berichten uber den Fall einer Gefasperforation nach PTCA mit Shuntbildung von der rechten Koronararterie in den rechten Ventrikel, wobei der Shuntflus sowohl kernspintomographisch als auch dopplersonographisch dargestellt werden konnte.

Quantitative Assessment of Right Ventricular Volumes in Severe Chronic Thromboembolic Pulmonary Hypertension using Transthoracic Three-dimensional Echocardiography: Changes due to Pulmonary Thromboendarterectomy

Evaluation of a three-dimensional reconstruction method to show the changes of right ventricular volume and systolic function when patients undergo pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension.In the examination of 11 patients (four female, seven male; age 56+/-10 years) before and after pulmonary thromboendarterectomy, end-diastolic and end-systolic right ventricular volumes were determined as a sum total of the calculated volumes of derived parallel slices of the right ventricle. Using a Tomtec workstation and a Vingmed CFM 800 echocardiography device, the acquired data were ECG-and respiration-triggered in the course of transthoracic examination, usin…

Short and long term results after intracoronary stenting in human coronary arteries: monocentre experience with the balloon-expandable Palmaz-Schatz stent.

OBJECTIVE--Intracoronary stenting was designed to overcome acute complications after percutaneous transluminal coronary angioplasty and to achieve a reduced rate of restenosis, both of which are major limitations of this well accepted method for treating coronary heart disease. This report describes the experience at one centre with the implantation of balloon-expandable Palmaz-Schatz stents and focuses on device related complications and the short and long term angiographic outcome. DESIGN--A retrospective data analysis. PATIENTS--Stenting was attempted in 50 patients. Restenosis after an initially successful angioplasty procedure, inadequate postangioplasty results, saphenous coronary byp…

A framework for PACS development in cardiology

The authors develop a framework for the integration of cardiology into hospitalwide picture archiving and communication systems (PACSs) by the definition of user requirements in cardiology image information systems. These user requirements have to be based on the consensus of users and industry. A topdown layered scheme is proposed for the development of documents based on user requirements. The structure of committees within the European Society of Cardiology that are working in this field is discussed. >

Measurement of Wγ and Zγ production cross sections in pp collisions at s=7 TeV and limits on anomalous triple gauge couplings with the ATLAS detector

This Letter presents measurements of l(+/-) nu gamma and l(+)l(-)gamma (l = e.mu) production in 1.02 fb(-1) of pp collision data recorded at root s = 7 TeV with the ATLAS detector at the LHC in the ...

Computerized estimation of quality standards for the X-ray densitometric assessment of myocardial perfusion

The densitometric evaluation of heart-phase-gated digital subtraction coronary angiograms derives different parameters which provide information about coronary blood flow, myocardial perfusion, and coronary flow reserve: appearance time, rise time, mean ascending time, and maximum intensity. The reliability and reproducibility of these measurements and of the derived parameters were investigated. Four digital subtraction coronary angiograms were obtained in ten patients, including two baseline measurements and two measurements under hyperemia induced by papaverine ic. Different reproducibility results were found for the parameters, depending on the heart phase of the densogram (diastolic be…

Search for long-lived stoppedR-hadrons decaying out of time withppcollisions using the ATLAS detector

An updated search is performed for gluino, top squark, or bottom squark R-hadrons that have come to rest within the ATLAS calorimeter, and decay at some later time to hadronic jets and a neutralino, using 5.0 and 22.9 fb(-1) of pp collisions at 7 and 8 TeV, respectively. Candidate decay events are triggered in selected empty bunch crossings of the LHC in order to remove pp collision backgrounds. Selections based on jet shape and muon system activity are applied to discriminate signal events from cosmic ray and beam-halo muon backgrounds. In the absence of an excess of events, improved limits are set on gluino, stop, and sbottom masses for different decays, lifetimes, and neutralino masses. …

Search for a scalar or vector particle decaying into Zγ in pp¯ collisions at s=1.96 TeV

We present a search for a narrow scalar or vector resonance decaying into Z gamma with a subsequent Z boson decay into a pair of electrons or moons. The data for this search were collected with the D circle divide detecror at the Fermilab Tevatron p (p) over bar collider at a center of mass energy root s = 1.96 TeV. Using 1.1 (1.0) fb(-1) of data, we observe 49 (50) candidate events in the electron (muon) channel, in good agreement with the standard model prediction. From the combination of both channels, we derive 95% C.L. upper limits on the cross section times branching fraction (sigma x B) into Z gamma. These limits range from 0.19 (0.20) pb for a scalar (vector) resonance mass of 600 G…

Performance of $b$-Jet Identification in the ATLAS Experiment

We thank CERN for the very successful operation of the LHC, as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, HGF, and MPG, Germany; GSRT, Greece; RGC, Hong Kong SAR, China; ISF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT an…

Mechanism of reperfusion damage after thrombolysis and ‘direct PTCA’

Summary There is general agreement between cardiologists, that reperfusion of the infarct related coronary artery (PTCA) is the method of choice for the treatment of an acute myocardial infarction. However, the method utilized for inducing a rapid and complete reperfusion is still discussed. Even if thrombolysis will remain the method of choice for the major part of the population, part of the patient cohort with acute infarction will be treated by direct PTCA. Rapid reperfusion of ischemic myocardium reduces infarct size by limiting infarct extension into the entire area at risk, although a reperfusion damage is induced in the core ischemic area. This reperfusion damage has been convincing…

Homozystein, Methylentetrahydrofolatreduktase/C677T-Genotyp und Risiko für koronare Herzkrankheit

Ambulatory follow-up of aortic dissection by transesophageal two-dimensional and color-coded Doppler echocardiography.

Follow-up of 18 patients with aortic dissection (five with type I, one with type II, 11 with type III dissection according to DeBakey) by transesophageal, two-dimensional and color-coded Doppler echocardiography showed a persistence of the false lumen in five of seven patients (71%) after surgery and in nine of 11 patients (82%) after medical therapy. In two patients treated with surgery, the dissected part of the aorta had been resected, whereas in two patients treated medically, a progressive and complete obliteration of the false lumen was observed. In the false lumen, thrombus formation was absent in four, localized in four, and progressive in six patients. Flow within the false lumen c…

Left ventricular function analyzed by Doppler and echocardiographic methods in short-term hypothyroidism

Abstract In conclusion, a significant reversible decrease in contractility and an impaired diastolic relaxation was demonstrated in patients with short-term hypothyroidism. This must be considered in patients with preexisting heart disease.

Search for excited electrons and muons in root s=8 TeV proton-proton collisions with the ATLAS detector

The ATLAS detector at the Large Hadron Collider is used to search for excited electrons and excited muons in the channel pp → ℓℓ* → ℓℓγ, assuming that excited leptons are produced via contact interactions. The analysis is based on 13 fb[superscript −1] of pp collisions at a centre-of-mass energy of 8 TeV. No evidence for excited leptons is found, and a limit is set at the 95% credibility level on the cross section times branching ratio as a function of the excited-lepton mass m[subscript ℓ*]. For m[subscript ℓ*] ≥ 0.8 TeV, the respective upper limits on σB(ℓ* → ℓγ) are 0.75 and 0.90 fb for the e* and μ* searches. Limits on σB are converted into lower bounds on the compositeness scale Λ. In …

Search for a heavy Standard Model Higgs boson in the channel H→ZZ→ℓ+ℓ−qq¯ using the ATLAS detector

A search for a heavy Standard Model Higgs boson decaying via H -> ZZ -> l(+)l(-)q (q) over bar, where l = e, mu, is presented. The search is performed using a data set of pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.04 fb(-1) collected in 2011 by the ATLAS detector at the CERN LHC collider. No significant excess of events above the estimated background is found. Upper limits at 95% confidence level on the production cross section (relative to that expected from the Standard Model) of a Higgs boson with a mass in the range between 200 and 600 GeV are derived. Within this mass range, there is at present insufficient sensitivity to exclude a Standard Model Hi…

Measurements of the electron and muon inclusive cross-sections in proton–proton collisions at s=7 TeV with the ATLAS detector

This Letter presents measurements of the differential cross-sections for inclusive electron and muon production in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV, using data collected by the ATLAS detector at the LHC. The muon cross-section is measured as a function of p(T) in the range 4 < p(T) < 100 GeV and within pseudorapidity vertical bar eta vertical bar < 2.5. In addition the electron and muon cross-sections are measured in the range 7 < p(T) < 26 GeV and within vertical bar eta vertical bar < 2.0, excluding 1.37 < vertical bar eta vertical bar < 1.52. Integrated luminosities of 1.3 pb(-1) and 1.4 pb(-1) are used for the electron and muon measurements, respecti…

Coronary stent implantation in acute vessel closure 48 hours after an unsatisfactory coronary angioplasty

We report the implantation of a balloon-expandable stent in a patient with acute vessel closure in the state of evolving myocardial infarction following 48 hr after unsatisfactory coronary angioplasty. The stent was implanted after successful recanalization of an occluded left anterior descending artery, with repeated unsatisfactory results of balloon angioplasty. Adjunct thrombolytic therapy was contraindicated. No residual stenosis was documented in immediate control angiograms, or after 24 hr, 3 weeks, and 4 months.

Measurement of the top quark-pair production cross section with ATLAS in pp collisions at $\sqrt{s}=7$  TeV

A measurement of the production cross-section for top quark pairs($\ttbar$) in $pp$ collisions at $\sqrt{s}=7 \TeV$ is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in two different topologies: single lepton (electron $e$ or muon $\mu$) with large missing transverse energy and at least four jets, and dilepton ($ee$, $\mu\mu$ or $e\mu$) with large missing transverse energy and at least two jets. In a data sample of 2.9 pb-1, 37 candidate events are observed in the single-lepton topology and 9 events in the dilepton topology. The corresponding expected backgrounds from non-$\ttbar$ Standard Model processes are estimated using data-driv…

Measurement of multi-jet cross sections in proton-proton collisions at a 7 TeV center-of-mass energy

Inclusive multi-jet production is studied in proton–proton collisions at a center-of-mass energy of 7 TeV, using the ATLAS detector. The data sample corresponds to an integrated luminosity of 2.4 pb−1. Results on multi-jet cross sections are presented and compared to both leading-order plus parton-shower Monte Carlo predictions and to next-to-leading-order QCD calculations.

Search for supersymmetry in pp collisions at s=7 TeV in final states with missing transverse momentum and b-jets

Results are presented of a search for supersymmetric particles in events with large missing transverse momentum and at least one heavy flavour jet candidate in sqrt{s} = 7 TeV proton-proton collisions. In a data sample corresponding to an integrated luminosity of 35 pb-1 recorded by the ATLAS experiment at the Large Hadron Collider, no significant excess is observed with respect to the prediction for Standard Model processes. For R-parity conserving models in which sbottoms (stops) are the only squarks to appear in the gluino decay cascade, gluino masses below 590 GeV (520 GeV) are excluded at the 95% C.L. The results are also interpreted in an MSUGRA/CMSSM supersymmetry breaking scenario w…

Schrittmachertherapie bei Frühgeborenen mit AV-Block: Erstmaliger Einsatz von „Autocapture” mit epikardialer Elektrode

A search for t[bar over t] resonances in lepton+jets events with highly boosted top quarks collected in pp collisions at √s = 7 TeV with the ATLAS detector

A search for resonant production of high-mass top-quark pairs is performed on 2.05 fb[superscript −1] of proton-proton collisions at √s = 7 TeV collected in 2011 with the ATLAS experiment at the Large Hadron Collider. This analysis of the lepton+jets final state is specifically designed for the particular topology that arises from the decay of highly boosted top quarks. The observed t[bar over t] invariant mass spectrum is found to be compatible with the Standard Model prediction and 95% credibility level upper limits are derived on the t[bar over t] production rate through new massive states. An upper limit of 0.7 pb is set on the production cross section times branching fraction of a narr…

Experimental Discrimination between Charge2e/3Top Quark and Charge4e/3Exotic Quark Production Scenarios

We present the first experimental discrimination between the 2e/3 and 4e/3 top quark electric charge scenarios, using top quark pairs (ttbar) produced in ppbar collisions at sqrt{s}=1.96 TeV by the Fermilab Tevatron collider. We use 370 pb-1 of data collected by the D0 experiment and select events with at least one high transverse momentum electron or muon, high transverse energy imbalance, and four or more jets. We discriminate between b- and bbar-quark jets by using the charge and momenta of tracks within the jet cones. The data is consistent with the expected electric charge, |q|=2e/3. We exclude, at the 92% C.L., that the sample is solely due to the production of exotic quark pairs QQba…

Ein diagnostisch-therapeutischer Stufenplan bei instabiler Angina pectoris

Unter instabiler Angina pectoris wird 1. eine Crescendo-Angina-pectoris verstanden, die an Starke und Haufigkeit zunimmt oder sich auf eine bestehende typische Belastungs-Angina-pectoris aufpfropft, 2. eine Angina pectoris in Ruhe und bei minimaler Belastung und 3. eine neu auftretende Angina pectoris, die bei geringster Belastung ausgelost wird [3].

Search for microscopic black holes in a like-sign dimuon final state using large track multiplicity with the ATLAS detector

A search is presented for microscopic black holes in a like-sign dimuon final state in proton-proton collisions at √s= 8 TeV. The data were collected with the ATLAS detector at the Large Hadron Collider in 2012 and correspond to an integrated luminosity of 20.3 fb-1. Using a high track multiplicity requirement, 0.6±0.2 background events from Standard Model processes are predicted and none observed. This result is interpreted in the context of low-scale gravity models and 95% CL lower limits on microscopic black hole masses are set for different model assumptions.

Search for single b⁎-quark production with the ATLAS detector at s=7 TeV

The results of a search for an excited bottom-quark b* in pp collisions at root s = 7 TeV, using 4.7 fb(-1) of data collected by the ATLAS detector at the LHC are presented. In the model studied, a ...

Transverse momentum, rapidity, and centrality dependence of inclusive charged-particle production in sNN=5.02 TeV p+ Pb collisions measured by the ATLAS experiment

Measurements of the per-event charged-particle yield as a function of the charged-particle transverse momentum and rapidity are performed using p+Pbp+Pb collision data collected by the ATLAS experiment at the LHC at a centre-of-mass energy of sqrt (SNN) = 5.01 TeV. Charged particles are reconstructed over pseudorapidity |η|<2.3|η|<2.3 and transverse momentum between 0.1 GeV0.1 GeV and 22 GeV22 GeV in a dataset corresponding to an integrated luminosity of 1 μb−11 μb−1. The results are presented in the form of charged-particle nuclear modification factors, where the p+Pbp+Pb charged-particle multiplicities are compared between central and peripheral p+Pbp+Pb collisions as well as to charged-p…

Changes of neurohumoral parameters and endothelin-1 in response to exercise in patients with mild to moderate congestive heart failure

Plasma endothelin levels are increased in patients with moderate and severe CHF. Conflicting data exist about the endothelin-1 (ET) level in patients with mild to moderate CHF and the effect of maximal exercise on plasma ET levels.We determined the plasma levels of ET and various neurohumoral parameters in 93 patients with CHF in functional class II and III of the NYHA classification at rest and after maximal bicycle exercise. Baseline ET level was increased compared to an age-matched healthy volunteer group (6.95+/-0.31 vs 3.29+/-0.17 pg/ml, mean+/-S.E.M., P0.05), without significant differences between NYHA class II and III patients. Maximal exercise did not increase the ET level. In cont…

Experimentelle Untersuchungen zum Einsatz verschiedener atrialer Dipolkonfigurationen für die Vorhof-Stimulation mit VDD-Elektroden

Fourier-Analyse der P-Welle bei der VDD-Stimulation. Ein intra-individueller Vergleich verschiedener atrialer Dipolkonfigurationen

Der Frequenzinhalt der wahrgenommenen P-Welle wird bei der VDD-Stimulation sowohl von der Dipollokalisation, als auch von der Dipolkonfiguration beeinflust. Eine Vergroserung der Dipoloberflache resultiert in der Detektion tieferer Frequenzen.

Determination of myocardial perfusion and coronary flow reserve by densitometric measurements: a selective classification of regions of interest

To evaluate the functional effect of a coronary artery stenosis on the dependent myocardium, digitized coronary angiograms (DCAs) were recorded. The DCAs, acquired during heart catheterization, provide information about myocardial perfusion and coronary flow reserve of areas supplied by this coronary artery. For each analysis the myocardium is separated into different regions of interest (ROIs); 16 ROIs in the distribution of the LCA and 8 ROIs for the RCA. In addition to that, the ROIs of the diseased vessels are divided into ROIs which are proximal, within and distal to the stenosis. Using a semiautomatic procedure, densograms are constructed from which the parameter rise time is calculat…

Spontaneous plaque rupture visualized by intravascular ultrasound.

An intravascular ultrasound examination was performed in order to evaluate an angiographically complicated lesion. Intravascular ultrasound was able to demonstrate spontaneous plaque rupture in a patient with recent acute subendocardial infarction. The inconclusive angiographic appearance was clarified by the intravascular examination and led us to conclude that the myocardial infarction was due to plaque rupture with subsequent thrombotic occlusion, which had spontaneously resolved by the time of the study.

The effects of the nitric oxide donors molsidomine and SIN-1 on human polymorphonuclear leucocyte functionin vitro andex vivo

The nitrovasodilator and nitric oxide donor molsidomine and its metabolite SIN-I dilate vascular smooth muscle and inhibit platelet activation by increasing intracellular concentrations of cyclic GMP We have therefore studied the effects of molsidomine and SIN-I on isolated human polymorphonuclear leucocytes (PMN)in vitro andex vivo. In vitro molsidomine dose-dependently reducedβ-glucuronidase release and the generation of superoxide anions from non-activated and from FMLP- or PAF-stimulated human PMNs. SIN-1 was equally effective in reducing (β-glucuronidase release and totally inhibited oxygen radical generation at a concentration of 580 μmol · l−1. In a double-blind, placebo-controlled, …

Langzeitverlauf über 10 Jahre nach Ballondilatation bei stabiler und instabiler Angina pectoris

OBJECTIVE To assess the cardiac status of patients ten years after percutaneous transluminal coronary artery angioplasty (PTCA). PATIENTS AND METHODS Data of 534 patients (436 men, 98 women; mean age 53.2 +/- 8 years) in whom a PTCA had been performed between 1983 and 1986 were analysed, based on a questionnaire answered 121 +/- 11 months after the initial procedure. At the time of PTCA 184 patients (35%) had unstable angina, 350 (65%) stable angina. RESULTS 116 patients (63%) with unstable angina and 164 (47%) with stable angina had at least one cardiac event after the initial PTCA (repeat PTCA, bypass operation, myocardial infarction, death). None of these events occurred in 68 patients (…

Search for single production of scalar leptoquarks in pp¯ collisions decaying into muons and quarks with the D0 detector

We report on a search for second generation leptoquarks LQ_2 which decay into a muon plus quark in p\bar{p} collisions at a center-of-mass energy of sqrt{s} = 1.96 TeV in the D0 detector using an integrated luminosity of about 300 pb-1. No evidence for a leptoquark signal is observed and an upper bound on the product of the cross section for single leptoquark production times branching fraction beta into a quark and a muon was determined for second generation scalar leptoquarks as a function of the leptoquark mass. This result has been combined with a previously published D0 search for leptoquark pair production to obtain leptoquark mass limits as a function of the leptoquark-muon-quark cou…

Search for new phenomena in final states with large jet multiplicities and missing transverse momentum at s√=8 TeV proton-proton collisions using the ATLAS experiment

A search is presented for new particles decaying to large numbers (7 or more) of jets, with missing transverse momentum and no isolated electrons or muons. This analysis uses 20.3 fb[superscript −1] of pp collision data at s√ = 8 TeV collected by the ATLAS experiment at the Large Hadron Collider. The sensitivity of the search is enhanced by considering the number of b-tagged jets and the scalar sum of masses of large-radius jets in an event. No evidence is found for physics beyond the Standard Model. The results are interpreted in the context of various simplified supersymmetry-inspired models where gluinos are pair produced, as well as an mSUGRA/CMSSM model.

Measurement of the inelastic proton-proton cross-section at √s = 7 TeV with the ATLAS detector

The dependence of the rate of proton–proton interactions on the centre-of-mass collision energy, √s, is of fundamental importance for both hadron collider physics and particle astrophysics. The dependence cannot yet be calculated from first principles; therefore, experimental measurements are needed. Here we present the first measurement of the inelastic proton–proton interaction cross-section at a centre-of-mass energy, √s, of 7 TeV using the ATLAS detector at the Large Hadron Collider. Events are selected by requiring hits on scintillation counters mounted in the forward region of the detector. An inelastic cross-section of 60.3±2.1 mb is measured for ξ>5×10[superscript −6], where ξ is ca…

Echocardiography in myocardial infarction

This paper discusses the usefulness of echocardiography in thrombolysis, its diagnostic value and drawbacks for therapy and the possibilities for follow-up studies. The diagnostic value is seen in the possibility of localizing and defining the extent of myocardial infarction, not only of the left but also of the right ventricle, and recognizing the complications of myocardial infarction as soon as possible 1, 2, 4.

Short-and long-term outcome after PTCA in patients with stable and unstable angina

Acute results and follow-up data over a period of 36 months after attempted PTCA in 406 patients with stable angina and 202 patients with unstable angina are reported. The rate of acute complications (death, myocardial infarction and bypass grafting (CABG) amounted to 1.5% in stable and 6.4% in unstable patients (P less than 0.005). Within the first week after PTCA a significantly lower percentage (1.7% vs 10.4%) of cardiac events (death, myocardial infarction, CABG and repeat PTCA) was observed in the stable group (P less than 0.001). During a 12-month follow-up period, another 16.3% of the patients in the stable group and 30.7% of unstable patients suffered a new cardiac event (P less tha…

Assessment of successful valve reconstruction by intraoperative transesophageal echocardiography (TEE)

In 17 patients (10 patients with mitral insufficiency, 5 patients with tricuspid regurgitation, 2 patients with mitral stenosis) the result of valve reconstruction was evaluated by intraoperative two-dimensional transesophageal contrast-echocardiography (TEE). Therefore, 1–2 cc of an agitated contrast-medium (GelifundolR) were injected into the left or right ventricle. The result of reconstruction was assessed by the extent of regurgitant microbubbles into the left or right atrium. A successful valve repair could be demonstrated in 15 patients without or with only minimal regurgitation of contrast-fluid. In one patient residual severe mitral insufficiency after valve reconstruction could on…

A measurement of the ratio of the W and Z cross sections with exactly one associated jet in pp collisions at with ATLAS

The ratio of production cross sections of the W and Z bosons with exactly one associated jet is presented as a function of jet transverse momentum threshold. The measurement has been designed to ma ...

Anti-inflammatory properties of simvastatin on leukocyte-endothelial cell interactions following hemorrhagic shock

Background Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been shown to lower serum cholesterol levels. Recent studies reported that statins have vasculoprotective effects independent of their cholesterol-lowering properties. We studied simvastatin for its ability to modulate leukocyte-endothelial cell interactions under acute inflammation following hemorrhage and reperfusion. Methods The effects of simvastatin on leukocyte-endothelial cell interactions were observed by intravital microscopy in the rat mesenteric microcirculation and by immunohistochemical analyzes. Simvastatin (50 μg/kg or 100 μg/kg) was administrated intraperitoneally 18 h before study. Inf…

Search for pair production of heavy top-like quarks decaying to a high-pT W boson and a b quark in the lepton plus jets final state at s=7 TeV with the ATLAS detector

A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming a significant branching ratio for subsequent decay into a W boson and a b quark. The search is based on 4.7 fb(-1) of pp collisions root s = 7 TeV recorded in 2011 with the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, characterized by a high-transverse-momentum isolated electron or muon, large missing transverse momentum and at least three jets. The analysis strategy relies on the substantial boost of the W bosons in the t'(t') over bar signal when m(t') greater than or similar to 400 GeV. No significant excess of events above t…

Search for W′ boson production in the W′→tb¯ decay channel

We present a search for the production of a new heavy gauge boson W' that decays to a top quark and a bottom quark. We have analyzed 230 pb(-1) of data collected with the DO detector at the Fermilab Tevatron collider at a center-of-mass energy of 1.96 TeV. No significant excess of events above the standard model expectation is found in any region of the final state invariant mass distribution. We set upper limits on the production cross section of W' bosons times branching ratio to top quarks at the 95% confidence level for several different W, boson masses. We exclude masses between 200 and 610 GeV for a W' boson with standard-model-like couplings, between 200 and 630 GeV for a W, boson wi…

Three-dimensional imaging of cardiac mass lesions by transesophageal echocardiographic computed tomography.

Three-dimensional echocardiography is a new imaging technique that allows more realistic visualization of cardiac morphology. This study presents data about the diagnostic potentials of this technique concerning cardiac mass lesions, as well as its feasibility in clinical application. After the conventional investigation, multiple cross-sectional images were obtained during automatic forward advancement of a monoplane transducer mounted on a transesophageal probe. Three-dimensional reconstruction and volume determination were performed off line. Twenty-four patients were studied. In 14 cases results of echocardiographic computed tomography (echo-CT) were compared with those of monoplane/bip…