showing 36 of ~574560 from 574555 documents

Guinea pig Kupffer cells can be activated in vitro to an enhanced superoxide response

1988

Summary In the preceding paper it was shown that Kupffer cells isolated by digestion of the liver and purified by centrifugal elutriation can be activated in vitro by lipopolysaccharide and muramyl dipeptide to an enhanced superoxide response upon zymosan phagocytosis. Lipopolysaccharide and muramyl dipeptide also led to a strongly increased prostaglandin E 2 release during the phagocytosis of zymosan. This activation was accompanied by an increased production of prostaglandin E 2 during the incubation with the stimuli. Prostaglandin E 2 synthesis was inhibited by the cyclooxygenase inhibitor indomethacin, reduced by dexamethasone, but only slightly decreased by the lipoxygenase inhibitor n…

medicine.medical_specialtyLipopolysaccharidemedicine.medical_treatmentPhagocytosisPronaseBiologyLipoxygenasechemistry.chemical_compoundInternal medicinemedicineHepatologySuperoxideZymosanMolecular biologyIn vitroNordihydroguaiaretic acidEndocrinologymedicine.anatomical_structurechemistryBiochemistryHepatocytebiology.proteinlipids (amino acids peptides and proteins)CyclooxygenaseMuramyl dipeptideProstaglandin EJournal of Hepatology

Функционирование торговли в условиях торгово-промышленного комплекса

1988

В сборнике освещается основные направления совершенствования взаимоотношений промышленности и торговли как единого организационно-экономического механизма производства и реализации товаров народного потребления в новых условиях хозяйствования.

Торговая сетьТовары народного потребленияСпрос и предложениеTirgvedība:SOCIAL SCIENCES::Business and economics::Economics [Research Subject Categories]МаркетингПроизводство товаровТорговля

Coutume générale de Bourgogne et coutume d'Avallon devant le parlement (1323)

1988

International audience

Histoire du droit[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/LawComputingMilieux_MISCELLANEOUS[ SHS.DROIT ] Humanities and Social Sciences/Law

Chant funèbre pour les cadets de l'Alcazar: un conflit par ses signes

1988

Estudio de las estrategias del poeta para conseguir la adhesión del lector, en particular en la plano de las imágenes, en Chant funèbre pour les cadets de l'Alcazar, de Pierre Pascal.

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASPoesía francesa militante:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Guerra Civil EspañolaNacionales

Reduction of Dinitrogen to Ammonia in Irradiated Heterogeneous Systems

1988

The recent developments of the research in the field of dinitrogen reduction to ammonia at mild conditions of pressure and temperature are reported. After a brief historical recapitulation of the traditional thermal process, the new routes for NH3 synthesis (biological photosynthesis, direct electrochemical reduction, and photocatalytic reduction) are presented and critically discussed. A particular attention is devoted to heterogeneous photocatalytic reduction performed by irradiating pure, mixed, and doped semiconducting catalysts in gas-solid and liquid-solid systems. The fixation of dinitrogen in aqueous solutions containing complexes and photoactive particulate systems is also reported…

Ammoniachemistry.chemical_compoundAqueous solutionMaterials sciencechemistryScientific methodDopingInorganic chemistryPhotocatalysisIrradiationElectrochemistryPhotochemistryCatalysis

La "fécondité naturelle" et les Chartrains au 18e siècle

1988

Die transanale endoskopische Mikrochirurgie beim Rektumprolaps — Tierexperimentelle Ergebnisse

1988

Es werden die Technik und die tierexperimentellen Ergebnisse einer neuen endo-skopisch-mikrochirurgischen Methode zur Behandlung des Rektumprolaps demonstriert: Durchtrennung der dorsalen Rektumwand; Ablosung der Rektumhinterwand vom Kreuzbein in den oberhalb gelegenen Abschnitten; Transmurale Einzelnahte vom Darmlumen aus durch die prasacralen Ligamenta zum Darmlumen zuruck; Legen mehrerer solcher Pexie-Nahte; Verschlus der Incision. Die fur die Rektopexie konzipierte Technik sollte wegen ihrer geringen Invasivitat deshalb fur die uberwiegend alten Patienten mit Rektumprolaps gunstiger sein als konventionelle Techniken.

"Wielki Kalendarz Ilustrowany dla Wszystkich" : szkic monograficzny (w sześćdziesięciolecie wydawnictwa)

1988

Integral curves of derivations

1988

We integrate, by a constructive method, derivations of even degree on the sections of an exterior bundle by families of Z 2-graded algebra automorphisms, dependent on a real parameter, and which satisfy a flow condition. We also study the case of local endomorphisms when their components of degree zero and derivations and with no component of negative degree, but then we have integral families of R-linear automorphisms. This integration method can be applied to the Frolicher—Nijenhuis derivations on the Cartan algebra of differential forms, and to the integration of superfields on graded manifolds.

Filtered algebraAlgebraDifferential geometryFlow (mathematics)Differential formDifferential graded algebraGraded ringMathematics::Differential GeometryGeometry and TopologyAutomorphismAnalysisMathematicsGraded Lie algebraAnnals of Global Analysis and Geometry

Sobre elipsis y coordinación copulativa

1988

La gramática de tipo tradicional entendía que toda coordinación era, en realidad, una composición de dos oraciones (o más) en la segunda de las cuales podían suprimirse elementos ya aparecidos en la primera para evitar su repetición. El propóstio de este trabajo no es discutir los planteamientos de la RAE, sino mostrar que en la explicación de ciertas construcciones coordinadas se impone el recurso de la elipsis.

gramática liminarelipsisUNESCO::LINGÜÍSTICA::Lingüística sincrónica:LINGÜÍSTICA::Lingüística sincrónica [UNESCO]:LINGÜÍSTICA::Teoría lingüística [UNESCO]UNESCO::LINGÜÍSTICA::Teoría lingüísticacoordinación

Purification and molecular weight determination of the membrane protein cytochrome o-complex from Rhodospirillum rubrum by high-performance liquid ch…

1988

ChromatographyCytochromebiologyChemistryClinical BiochemistryRhodospirillum rubrumGeneral Medicinebiology.organism_classificationHigh-performance liquid chromatographyAnalytical ChemistryMembrane proteinProtein purificationbiology.proteinGeneral Materials ScienceFresenius' Zeitschrift für analytische Chemie

The adenoid cystic carcinoma

1988

Summary In spite of its rare incidence the adenoid cystic carcinoma must be treated with respect because of its hidden malignant character. In 5 out of 21 patients recurrences occurred much longer than5 years after he first operation. The extension of this tumour along branches of the trigeminal nerve could be well demonstrated in 7 of our patients where we were able to produce histological proof or radiographic evidence. The theory of tumour growth along the “tissue of least resistance” is illustrated by a special case report. As for the therapy, ultra-radical surgery has proved to be the most effective so far, whereas radio- or chemotherapy were only useful as palliative measures.

Trigeminal nervemedicine.medical_specialtyChemotherapybusiness.industryAdenoid cystic carcinomaRadiographyIncidence (epidemiology)medicine.medical_treatmentmedicine.diseaseSurgeryOtorhinolaryngologymedicineSalivary gland tumourSurgeryOral SurgerybusinessJournal of Cranio-Maxillofacial Surgery

Isolation and identification of roseotoxin S from cultures of the fungus Trichothecium roseum

1988

The structure of reseotoxin S, a new cyclodepsipeptide of the fungus Trichothecium roseum, is described. It consists of three amino acids and two hydroxy acids. Besides the structure, possibilities of proof and isolation as well as analytical data are given.

chemistry.chemical_classificationbiologyChemistryStereochemistryClinical BiochemistryGeneral MedicineFungusFungi imperfectibiology.organism_classificationIsolation (microbiology)Analytical ChemistryAmino acidTrichothecium roseumGeneral Materials ScienceFresenius' Zeitschrift für analytische Chemie

Control of Acetylcholine Release and of Intestinal Motility by Subtypes of Muscarine Receptors

1988

Two types of neuronal muscarine receptors have been investigated in the myenteric plexus preparation of the guinea-pig small intestine: 1. Presynaptic receptors activation of which inhibits the depolarization-evoked release of acetylcholine. Pirenzepine and dicyclomine have low affinities to the release-inhibitory receptors (pA2 values 6.9 and 7.6) which suggests that the presynaptic receptors (similar to the smooth muscle receptors) belong to the M2 subtype. The inhibition of the electrically-evoked acetylcholine release by muscarine (0.01 - 1 μmol/1) was not affected by forskolin (1μmol/l). This indicates that cyclic AMP is not crucially involved in the muscarinic inhibition of acetylchol…

medicine.medical_specialtyMuscarineChemistryMuscarinic acetylcholine receptor M1BicucullineDicyclominePirenzepinechemistry.chemical_compoundEndocrinologyInternal medicineMuscarinic acetylcholine receptormedicineReceptorAcetylcholinemedicine.drug

Prognose nach Resektion von Lebermetastasen kolorektaler Karzinome

1988

Im Zeitraum von 1978–1986 wurden 51 Patienten wegen Lebermetastasen kolorektaler Karzinome operiert. Metastasenrezidive traten in 89% auf. Die Funf-Jahres-Uberlebensrate betrug 10,7%, die mediane Uberlebenszeit 24 Monate. Die Operationsletalitat lag bei 7,8%. Die Uberlebenszeit war statistisch signifikant langer als die eines Vergleichskollektives unserer Klinik mit Spontanverlauf von Lebermetastasen. Die Hohe des CEA-Spiegels korrelierte signifikant mit dem Volumen der resezierten Metastasen. Anzahl, Lokalisation und Volumen der Metastasen, Hohe des CEA-Spiegels, Tumordifferenzierung, Stadium und Lokalisation des Primartumors und Art der Operation hatten keinen Einflus auf das Uberleben.

Silver ion oxidative coupling of diene and triene-diolates of unsaturated carboxylic acids. A facile synthesis of octa- and dodeca-dienedioic acids

1988

Abstract Polyunsaterated dicarboxylic acids 3 and 5 are very easily prepared by oxidative coupling of lithium diene- and triene-diolates 1 and 2 with silver nitrate.

Silver nitratechemistry.chemical_compoundDieneChemistryOrganic ChemistryDrug DiscoveryOrganic chemistrychemistry.chemical_elementSilver ionLithiumOxidative coupling of methaneBiochemistryTetrahedron Letters

Zum Ligandenaustausch des Ferrocens mit Methyl- und Ethyl-substituierten Naphthalinen

1988

Abstract The replacement of a Cp ligand of ferrocene by each of ten unsymmetrically substituted naphthalenes yields pairs of complex ions [arene-FeCp] + , which have been identified from their 1 H NMR spectra. The influence of the substituent on the ratio of the two isomers, and its temperature dependence implies a complex reaction mechanism involving an η 2 -bound intermediate of the associated naphthalene. The proton resonances of the alkyl groups of the naphthalenes are shifted to lowfield by complexation; this effect decreases with increasing distance from the iron. The resonance shift of the arene protons has a different sign for the complexed (highfield) and the uncomplexed part (lowf…

chemistry.chemical_classificationReaction mechanismStereochemistryLigandOrganic ChemistrySubstituentNuclear magnetic resonance spectroscopyBiochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryFerroceneMaterials ChemistryProton NMRPhysical and Theoretical ChemistryMetalloceneAlkylJournal of Organometallic Chemistry

Strategia polityczna Włoskiej Partii Komunistycznej

1988

Rezeptoren für Neurotransmitter und psychiatrische Erkrankungen

1988

business.industryMedicinebusiness

La estructura de la teoría de la evolución

1988

UNESCO::FILOSOFÍA:FILOSOFÍA [UNESCO]Biology Evolution and Development

Complex Metabolic Activation Pathways of Polycyclic Aromatic Hydrocarbons: 3-Hydroxy-trans-7,8-Dihydroxy-7,8-Dihydrobenzo[a]Pyrene as a Proximate Mut…

1988

3-Hydroxybenzo[a]pyrene (3-OH-BP) is a major metabolite of benzo[a]pyrene (BP) in various systems. Metabolites of 3-OH-BP, formed by liver enzymes, bind to DNA1,2 and are mutagenic3,4. However, the active species have not yet been identified. Administration of 3-OH-BP to rats results in the excretion of sulfate and glucuronic acid conjugates of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene (3-OH-BP-7,8-diol) (Fig. 1) as major metabolites in the bile5. The hydroxyl groups of this triol are structurally superimposable to those of 9-hydroxy-trans-1,2-dihydroxy-1,2-dihydrochrysene (9-hydroxychrysene-1,2-diol, Fig. 1), which is a metabolite of chrysene6,7 and a potent promutagen8,9. 9-…

chemistry.chemical_classificationChryseneStereochemistryMetabolitePolycyclic aromatic hydrocarbonMutagenmedicine.disease_causechemistry.chemical_compoundchemistryCarbonium ionmedicineOrganic chemistryPyreneTriolCarcinogen

Larval competition in Drosophila melanogaster: frequency-dependence of viability

1988

The application of the overfeeding technique (interruption of the competition during larval development) to the study of larval competition in two-strain cultures of Drosophila melanogaster demonstrates the following points: (1) viability is a function of competition time; (2) viability becomes more frequency-dependent as competition time increases; (3) the dynamics of the “inner” subpopulation (adults that have passed all their development in a crowded condition) and “outer” subpopulation (adults coming from larvae recovered by interruption of competition) vary with time as regards frequency-dependence; and (4) the wild type strain Oregon is the active agent in competition with the strain …

LarvabiologyEcologymedia_common.quotation_subjectfungiFrequency-dependent selectionZoologyGeneral MedicineFrequency dependencebiology.organism_classificationCompetition (biology)Intraspecific competitionDrosophilidaeGeneticsDrosophila melanogasterAgronomy and Crop ScienceBiotechnologymedia_commonWild type strainTheoretical and Applied Genetics

Postersitzung 13: Inkontinenz — Harnabflußstörungen

1988

Den guten Fruhresultaten von 80–90% stehen masige Langzeiterfolgsquoten von 50–70% nach 5 Jahren bei den bekannten urethralen Suspensionsmethoden entgegen. Aus der Schlusfolgerung, das primar befriedigende funktionelle Verhaltnisse vorliegen, ergibt sich der Ansatz, durch Optimierung bereits bestehender Verfahren bessere Langzeitergebnisse anzustreben.

Comment optimiser l'analyse sensorielle ?

1988

National audience

[SDV] Life Sciences [q-bio][SDV]Life Sciences [q-bio]ORGANE SENSORIELLEComputingMilieux_MISCELLANEOUS

Epistémologie du concept de sélection (analyse critique de E. Sober, The Nature of Selection)

1988

National audience

[SHS.HISPHILSO]Humanities and Social Sciences/History Philosophy and Sociology of Sciencesépistémologie[SHS.HISPHILSO] Humanities and Social Sciences/History Philosophy and Sociology of SciencessélectionComputingMilieux_MISCELLANEOUS[ SHS.HISPHILSO ] Humanities and Social Sciences/History Philosophy and Sociology of Sciences

Le fisc en Parisis et les dotations san-dyonisiennes

1988

catalogue d'exposition J. Cuisenier, R. Guadagnin; International audience

[SHS.HIST] Humanities and Social Sciences/Historydomaines seigneuriaux laïquesCapitales et chefs-lieuxStructures administratives[SHS.HIST]Humanities and Social Sciences/HistoryCirconscriptions

Zentral dämpfende Wirkstoffe, 7. Mitt. Kernsubstituierte (Diallylamino)-1,3,5-triazine

1988

Aus der Umsetzung von 2,4-Dichlor-6-(diallylamino)-1,3,5-triazin (1) mit langkettigen primaren (2a-b) und cyclischen sekundaren (2c-f) Aminen gehen die kernsubstituierten Chlor-diallylamino-1,3,5-triazine (3a-f) hervor. Ein fur Strukturtyp 3 charakteristischer ms Fragmentierungsweg beinhaltet die Umbildung der Diallylaminogruppe zum Aziridinring. Unter den neu entwickelten Verbindungen findet sich zentral dampfende Wirksamkeit besonders in 3a ausgepragt. Daruber hinaus weist Strukturtyp 3 Antiprotozoen-, anthelminthische und insektenwachstumsregulatorische Wirkung auf. CNS Depressants, VII: (Diallylamino)-1,3,5-triazines Substituted at the Triazine Nucleus The reaction of 2,4-dichloro-6-(di…

chemistry.chemical_compoundchemistryStereochemistryCns depressantDrug DiscoveryPharmaceutical ScienceCns depressantsAziridineMass spectrometricTriazineArchiv der Pharmazie

ЭВМ в образовании. Программное обеспечение

1988

Сборник посвящен научным и методическим проблемам адаптации, разработки и стандартизации педагогических программных средств (ППС) для применения при изучении информатики и вычислительной техники, предметов естественно-научного цыкла, а также разработке некоторых инструментальных средств создания ППС.

Электронно вычислительные машиныЭВМ в образованииОбучающие программыОбучение информатикеПедагогические программные средства:SOCIAL SCIENCES::Statistics computer and systems science::Informatics computer and systems science::Informatics [Research Subject Categories]Informātika

Experimental Evidence for Shape Coexistence in 97Sr59 and Implications for the Structure of the Odd-Odd Isotone 98Y

1988

Experimental evidence for shape coexistence in the odd-mass N=59 isotone 97Sr is presented. The ground state and the lowest excited levels of 97Sr are shown to be spherical, whereas a rotational band based on a state at 585 keV has been identified. Three further levels of deformed origin are proposed. Nilsson-orbital assignments are supported by RPA shell-model calculations. These findings lead to a better understanding of the structure of the odd-odd N=59 isotone 98Y.

PhysicsExcited stateIsotoneNuclear TheoryStructure (category theory)State (functional analysis)Atomic physicsGround state

Sulla revisione dei canoni enfiteutici e Sulla ammissibilità della domanda riconvenzionale tendente ad ottenere la revisione del canone in corso di g…

1988

canoni enfiteuticigiudizio di affrancazione

La mitologia antica tra umanesimo e totalitarismo ideologico nel pensiero di Károly Kerényi

1988

La funzione ambigua del mito nella cultura del Novecento ha consentito alle ideologie totalitarie di strumentalizzarlo e manipolarlo a fini di propaganda e di controllo culturale. L'opera di Kerényi si colloca in controtendenza, a sostegno di una visione della mitologia antica diretta alla valorizzazione di un nuovo umanesimo.

Settore L-ANT/02 - Storia GrecaKerényi mitologia totalitarismi manipolazione umanesimo

Considerazioni sul riconoscimento formale delle bellezze naturali

1988

Riconoscimento formale delle bellezze naturali

La apicultura valenciana: Un aprovechamiento agrario tradicional

1988

LA APICULTURA VALENCIANA ES UNA ACTIVIDAD TRADICIONAL Y MUY ARRAIGADA EN LA COMUNIDAD VALENCIANA QUE COLOCA A ESTA REGION EN LA CABEZA NACIONAL. ELLO SE DEBE A UNAS IDONEAS CONDICIONES CLIMATICAS Y BOTANICAS QUE LA HACEN ESPECIALMENTE APTA PARA EL DESARROLLO DE ESTE APROVECHAMIENTO AGRARIO. ADEMAS, AQUI COINCIDEN LA MAYOR PARTE DE LAS INDUSTRIAS Y ACTIVIDADES RELACIONADAS CON LA MIEL. LA EXPLOTACION APICOLA VALENCIANA SE CARACTERIZA POR DOS ASPECTOS FUNDAMENTALES: UN TALANTE ECONOMICO COMPLEMENTARIO QUE PROPORCIONA INGRESOS ADICIONALES A UNA AGRICULTURA INSUFICIENTE, Y LA TRASHUMANCIA, ORIENTACION PRODUCTIVA QUE REALIZA IMPORTANTES DESPLAZAMIENTOS TERRITORIALES EN BUSCA DE DIVERSAS FLORACIO…

UNESCO::HISTORIAGeografíaTrashumanciaUNESCO::HISTORIA::Historia por épocas::Historia antiguaGeociencias. Medio ambienteActividades agrariasFactores climáticos:HISTORIA::Historia por épocas::Historia antigua [UNESCO]ComarcasProducción agrariaDistribución espacialGrupo B:HISTORIA [UNESCO]ApiculturaAnálisis comparativo

The Inhibitory Effects of Prednisone, 16-Methylen-Prednisolone, and Acth on Con-A Induced Lymphokines (Interferon-Y) as Measured by the Chemiluminesc…

1988

When lymphocytes are stimulated with mitogens or antigens they are enhanced via a cascade of lymphokines to produce interferon-y (IFN-y). IFN-y augments the H2O2 secretion of human monocytes which indirectly can be measured by chemiluminescence. We tested prednisone, 16-methylen-prednisolone and ACTH for their effect to inhibit the Con-A induced stimulation of the chemiluminescence-activity. All three hormones inhibited significantly the stimulation: prednisone up to 52.5% (concentration = 150 micrograms/ml, p = 0.000005), 16-methylen-prednisolone up to 22.5% (concentration = 2.5 micrograms/ml, p = 0.006) and ACTH up to 33% (concentration = 10 micrograms/ml, p = 0.0036).

medicine.medical_specialtymedicine.drug_classPrednisoloneImmunologyDose-Response Relationship ImmunologicStimulationAdrenocorticotropic hormoneToxicologyMonocytesInterferon-gammaAdrenocorticotropic HormoneInternal medicineConcanavalin AmedicineHumansImmunology and AllergyInterferon gammaPharmacologybiologybusiness.industryMonocyteLymphokineHydrogen PeroxideGeneral Medicinemedicine.anatomical_structureEndocrinologyConcanavalin ALuminescent Measurementsbiology.proteinPrednisolonePrednisoneCorticosteroidbusinessmedicine.drugImmunopharmacology and Immunotoxicology

L'Alta Corte per la Regione siciliana tra autonomia regionale e Costituzione. la reltà delle Costituzioni straniere

1988

the essay investigates the institution of the Sicilian High Court to understand the reasons for its origin and its value as a possible organ in a modern conception of the phenomenon of autonomy, even in a centralized control system of constitutionality

Settore IUS/09 - Istituzioni Di Diritto PubblicoAlta Corte siciliana autonomia costituzione

Gabriel Marcel : un pensador no individualista en la sociedad abierta

1988

:CIENCIAS JURÍDICAS [UNESCO]PhilosophyUNESCO::CIENCIAS JURÍDICAS