showing 36 of ~574560 from 574555 documents

Cytochemical Cell Typing of Metastatic Tumors According to their Cytoskeletal Proteins

1986

Conventional staining methods alone are often insufficient to make accurate histodiagnosis of malignant tumors. However, additional information about the cell type and the state of differentiation of tumor cells can be provided by several molecular markers. To be relevant diagnostically, these markers must be conservative, i.e. expressed not only in well differentiated tumors but also in poorly differentiated tumors and in metastases. These criteria are fulfilled by certain components of the cytoskeleton, notably the proteins forming the intermediate-sized filaments (IFs) and the desmosomal plaque proteins.

Cell typePoorly differentiatedCancer researchTumor cellsCell typingBiologyCytoskeletonStainingCell biologyMetastatic carcinomaWell differentiated

Implementation of algorithms forK shortest loopless paths

1986

Implementations of loopless k shortest path algorithms are examined. Efficient storage structures for a large number of paths are given. A fast algorithm for determining the shortest paths in Yen's method is developed. Timing experiments show that a hybrid of Clarke's and Yen's methods is generally the fastest, although not significantly. Using upper bounds for the lengths of paths essentially improves all methods.

Computer Networks and CommunicationsHardware and ArchitectureShortest path problemK shortest path routingFloyd–Warshall algorithmAlgorithmFast algorithmYen's algorithmSoftwareInformation SystemsMathematicsNetworks

Luxación traumática bilateral mixta de cadera

1986

Se presenta un caso de luxación traumática bilateral mixta de cadera, en un paciente de 25 años de edad, revisándose la bibliografía de la patología traumática luxativa rara a nivel de esta articulación, en función a la edad y a las lesiones asociadas.

UNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS [UNESCO]

Ministère de la Culture, Sous-Direction de l'Archéologie, Direction des Antiquités Historiques de Bourgogne, fouilles du Mont Beuvray, campagne 1986

1986

Ce rapport rend compte des travaux effectués au cours de l'année 1986 dans le cadre du programme de recherche sur le Mont Beuvray sous la direction scientifique de Bibracte (Jean-Paul Guillaumet, coordonnateur scientifique).

Oppidum[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory

La Audiencia valenciana en la época foral moderna

1986

History European:GEOGRAFÍA [UNESCO]UNESCO::GEOGRAFÍA

El tratamiento periodístico de un problema secular : el laicismo en la escuela : Valencia, 1900-1910

1986

Se reflexiona a cerca de la necesidad de la prensa periódica como instrumento imprescindible para el conocimiento histórico, porque acerca a lo vivencial de cada pueblo. Es un medio de comunicación social que conoció un fuerte desarrollo y arraigo tras la Restauración borbónica, y al referirse en particular a la demarcación valenciana, en donde a pesar del alto índice de analfabetismo, se contaba, ya en 1900, con buenos y varios rotativos, siendo los de mayor tirada y aceptación popular El Pueblo, La Voz de Valencia, El Mercantil Valenciano, Las Provincias, La Correspondencia de Valencia, El Correo, El Siglo, etc. ESP

educación laicahistoria de la educaciónEspañahistoria contemporáneaprensa

Hydrologie et mise en valeur des ressources en eau

1986

National audience

[SDV] Life Sciences [q-bio][SDV]Life Sciences [q-bio]ComputingMilieux_MISCELLANEOUS

Economical influence and competition into urban area. Measuring test

1986

Définition et propriétés générales de l'indicateur d'influence effective, illustration sur un exemple numérique (agglomération découpée en six zones). Résultats d'une application au cas de l'agglomération dijonnaise (découpage en 20 quartiers; les douze communes périphériques sont retenues dans l'application). On relie onze fonctions de biens et de services: alimentation; équipement de la personne, équipement de la maison; autres commerces spécialisés; pharmacie, optique, orthopédie; services médicaux; services paramédicaux; bureaux de poste; banques et établissements financiers; éducation secondaire spécialisée; hôtellerie. Test de plusieurs simulations relatives à diverses répartitions de…

MeasurementZone urbaineMarché économiqueUrban areaGénéralitésConcurrence[SHS.ECO]Humanities and Social Sciences/Economics and FinanceUrbanismeInfluenceCompétitionMesure[ SHS.ECO ] Humanities and Social Sciences/Economies and financesEconomic marketTown planningQuartier voisinageQuartier Dijon France[SHS.ECO] Humanities and Social Sciences/Economics and FinanceNeighbourhoodGeneralInfluence économique

Choisir sa population pour gagner les élections ? Une études sur les municipales de 1953 à 1983

1986

Based on a regression analysis of French demographic and electoral data, 1953-1983, three relations suggested by theory appear confirmed: big cities tend to vote more for the right when compared to their own population the population of their suburbs is large; the distribution of the population of the urban area between the central city and the suburbs depends very significantly on the relation between the city's surface and the whole area's population ; the mayors of the central cities objectively influence the development of the distribution of the whole area's population in a way that is favorable to their reelection.

[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationFranceScience politique[SHS.SCIPO] Humanities and Social Sciences/Political science[SHS.SCIPO]Humanities and Social Sciences/Political scienceÉlection

Dos lienzos de Luciano Salvador Gómez en la Universidad de Valencia

1986

UNESCO::HISTORIA::Historia por épocas::Historia antigua:HISTORIA::Historia por épocas::Historia antigua [UNESCO]Pintura barroca

Condrolisis idiopática de la cadera

1986

UNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS [UNESCO]

An approach to erythrophleum alkaloids. Synthesis of methyl (−)-4-epi-cassamate

1986

Abstract A synthetic approach to Erythrophleum alkaloids, involving as a key-step the regiospecific deprotonation of the ketone 5a, is described.

chemistry.chemical_classificationKetonebiologyChemistryStereochemistryAlkaloidErythrophleumOrganic Chemistrybiology.organism_classificationBiochemistrychemistry.chemical_compoundDeprotonationDrug DiscoveryOrganic chemistryEpimerStereoselectivityEnantiomerDiterpeneTetrahedron Letters

Finding all optimal solutions to the network flow problem

1986

The problem examined in this paper is as follows: Given a feasible optimum basic solution (f.o.b.s) of the minimum cost network flow problem, find all the f.o.b.s of this problem. The existence of alternative f.o.b.s is characterized by means of elementary circuits of zero cost and length greater than two in the incremental graph associated to the given f.o.b.s. It is shown that any alternative f.o.b.s. can be obtained from the original one by circulating flow through elementary circuits belonging to a succession of incremental graphs. This result leads to the construction of an efficient algorithm to obtain all f.o.b.s. of the network flow problem.

Mathematical optimizationFlow (mathematics)Linear programmingComputer scienceCirculation problemMinimum-cost flow problemFlow networkMulti-commodity flow problemZero (linguistics)Electronic circuit

A CRF-Producing and -Secreting Tumor of the Lung

1986

Corticotropin-releasing factor (CRF) has recently been isolated from ovine hypothalamus, characterized chemically, and synthesized. Upton and Amatruda (1971) first suggested that CRF-like activity occurred in neoplastic tissues, and Hashimoto et al. (1980) subsequently detected CRF-like activity in an extract of an ACTHproducing nephroblastoma. Recently, Carey et al. (1984) and Asa et al. (1984) used immunocytochemical techniques to demonstrate CRF in postmortem tumor material obtained from patients with a carcinoma of the prostate and an intrasellar gangliocytoma.

endocrine systemPathologymedicine.medical_specialtyLungbusiness.industryTissue Polypeptide Antigenmedicine.diseasemedicine.anatomical_structureHypothalamusProstateCarcinomaMedicinebusinessCutaneous metastasisGangliocytomaInnominate veinhormones hormone substitutes and hormone antagonists

Terminology and Definitions

1986

In order to eliminate as much misunderstanding as possible in the evaluation of various forms of vibration stress, it is necessary to define the technical physical concepts used (Table 1). In addition, the special medical terms are explained at the end of the book (p. 158).

Physical ConceptsComputer scienceOrder (business)lawElectrical networkStress (linguistics)CalculusTable (database)Terminologylaw.invention

Televisión: lo cotidiano y lo autorreferencial. Los genéricos del telefilm

1986

En conclusión, hemos analizado algunos de los mecanismos de autorreferencialidad que caracterizan al discurso de telefilm a partir de sus genéricos, trabajo de diferenciación en el modelo hollywoodense que sirve de base al montaje de dichos espacios y aquí un rasgo todavía más de neutralización. Ello se ha materializado, en formas diversas, en una primera autorreferencialidad del episodio hacia sí mismo; en segundo, una autorreferencialidad que incluye a todas las demás y les imprime su sello tan indefectible como autoritario. Pues los telefilms están continuamente segmentados en su interior por espacios vacíos que sólo la publicidad puede llenar. Incluso podría afirmarse que el telefilm só…

UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASFalcon CrestTelevisión:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]TelefilmsRemington Steele

13C NMR of carbonyl compounds -4. Solution conformation of β-ionone and related dienones

1986

Abstract The steric factors relevant for the conformations of β-ionone and structurally related compounds were studied by dynamic n.m.r. and 1 H, 1 H-NOE measurements.

Steric effectschemistry.chemical_compoundCyclic compoundchemistryStereochemistryOrganic ChemistryDrug DiscoveryNuclear magnetic resonance spectroscopyNuclear Overhauser effectCarbon-13 NMRIononeBiochemistryEnoneTetrahedron Letters

Choline Fluxes to and from the Rat Cerebral Cortex Studied with the “Cup Technique” in Vivo

1986

Since MacIntosh and Oborin (11) and later Mitchell (12) introduced the “cup technique” as a mean to study acetylcholine release from the cerebral cortex in vivo, this technique has been widely used for investigating the release of various neurotransmitters in anaesthetized as well as unanaesthetized mammals (2, 13, 14). Recently we proposed the “cup technique” as a way for studying the efflux of endogenous choline (Ch) from the rat cerebral cortex (4, 5) and to estimate changes in the extracellular concentration of Ch, if we consider the fluid filling the cup as an extension of the extracellular space.

Endogenychemistry.chemical_compoundmedicine.anatomical_structurechemistryCerebral cortexIn vivoExtracellularBiophysicsmedicineCholinesense organsEffluxNeuroscienceAcetylcholinemedicine.drug

Verzeichnis der Teilnehmer an der Diskussion

1986

Active immunotherapy of stage IV renal cell cancer using autologous tumor cells

1986

A total of 53 patients with stage IV renal cell carcinoma were treated by vaccination with autologous tumor cells in Candida-antigen after palliative tumor nephrectomy. Follow-up has been up to 9 years. Complete remission within 48 months after nephrectomy was observed in 3 patients, while 6 showed partial remission and 18 are stable with disease. Of 26 patients with rapid progression, 17 died within 1 year after operation. The best response was seen in metastases to the liver and lung. CNS-lesions or bone metastases do not appear to respond to this treatment. We conclude that this mode of therapy is beneficiary to a certain group of patients and should be offered, as no severe side effects…

OncologyNephrologymedicine.medical_specialtyKidneymedicine.drug_classbusiness.industryUrologymedicine.medical_treatmentImmunotherapyActive immunotherapyMonoclonal antibodymedicine.diseaseNephrectomySurgerymedicine.anatomical_structureRenal cell carcinomaInternal medicinemedicineCarcinomabusinessWorld Journal of Urology

Changes in the probability of firing of motor units following electrical stimulation in human limb muscles

1986

Changes in the probability of motor unit firing was studied in ten different muscles (six muscles in the upper extremity and four muscles in the lower extremity) of eleven healthy human subjects. The responses were elicited by the electrical stimulation of cutaneous or mixed nerves during weak voluntary contraction of the muscle studied, and were recorded by averaging the rectified surface electromyogram. In eight of the ten muscles, well-detectable, short and long latency excitatory phases were observed. The most constant and well-identified excitatory responses were observed in the first interosseus dorsalis muscle in the hand, and in the extensor digitorum brevis muscle in the foot. Thes…

AdultMalePhysiologyNeural ConductionStimulationElectromyographyReflexmedicineHumansProbabilityMotor NeuronsLegmedicine.diagnostic_testElectromyographybusiness.industryMusclesAnatomyNeurophysiologyElectric StimulationMotor unitElectrophysiologyArmReflexExcitatory postsynaptic potentialFemalebusinessExtensor digitorum brevis muscleMuscle ContractionActa Physiologica Scandinavica

Традиции и новаторство в советской литературе

1986

Межвузовский сборник научных трудов посвящен важным историко-литературным и теоретическим проблемам русской советской литературы.

Русская литература:HUMANITIES and RELIGION::Aesthetic subjects::Literature [Research Subject Categories]Русская литература (история и критика)Krievu literatūras vēsture un kritika

L'aritocrazia valenzana: l'evoluzione di un gruppo privilegiato nella Spagna del XIX secolo

1986

Este artículo trata el problema de lo que realmente representó la aristocracia en el siglo XIX y su posición preeminente incluso después de la transformación liberal a partir del estudio del caso valenciano. Trata de poner de relieve las rupturas y continuidades, las transformaciones y la supervivencias en un proceso que comenzó a finales del Antiguo Régimen y llevó a un nuevo tipo de sociedad de carácter burgués y capitalista.

Història contemporània S.XIX

Koripallo penkkiurheiluna

1986

Tämä Suomen Koripalloliiltto ry:n ja Jyväskylän yliopiston liikuntasuunnittelun laitoksen yhteishankkeena toteutettu tutkimus koripallosta penkkiurheiluna on luonteeltaan kokeileva. Penkkiurheilua ja sen kiinnostavuuden lähteitä on toistaiseksi tutkittu vähän.

Les restes animaux du sanctuaire de Digeon (Somme)

1986

consultable sur : http://www.persee.fr/web/revues/home/prescript/article/pica_0752-5656_1986_num_3_1_1500; National audience; Sur les 3500 restes animaux issus des fouilles, 1850, bien localisés, ont été étudiés. A côté des mammifères domestiques classiques, des mammifères sauvages, cerf, sanglier, lièvre et loup, sont assez bien représentés. Il a également été recueillis des restes d'oiseaux.

trophées[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistorygallo-romainsanctuairearchéozoologiecerf

How to Bridge the Gap Between Membrane Biology and Polymer Science

1986

Can polymer chemists contribute to the understanding or even mimicking of cell membrane functions and cell-cell interactions? Fascinated by the specificity and efficiency of, for example, the destruction of tumor cells by lymphocytes (1) and having in mind what biochemical analyses tell us about membrane composition, we may try to “synthesize” membrane and cell models. The commonly used model systems, such as planar lipid monolayers at the gas-water interface, bimolecular lipid membranes and spherical liposomes, are much less stable than natural membrane systems (Figure 1).

chemistry.chemical_classificationLiposomeMaterials scienceCellMembrane biologyPolymerMembrane compositionCell membranemedicine.anatomical_structureMembranechemistryMonolayermedicineBiophysics

Relation of Interdiffusion and Self-Diffusion in Polymer Mixtures

1986

From different assumptions one obtains linear relationships either between the interdiffusion coefficient and the self-diffusion coefficients or between the inverse interdiffusion coefficient and the inverse self-diffusion coefficients. The nature of these assumptions and possible experiments for discriminating between them are discussed.

Condensed Matter::Soft Condensed Matterchemistry.chemical_classificationCondensed Matter::Materials ScienceSelf-diffusionLiquid stateChemistryInverseThermodynamicsPhysical chemistryPolymerPolymer blendComputer Science::Other

Les professeurs de législation des écoles centrales, témoins du droit privé intermédiaire

1986

Histoire du droit[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/Law[ SHS.DROIT ] Humanities and Social Sciences/Law

Metodología(s) del análisis de la imagen

1986

Presentación metodológica de las distintas aproximaciones al estudio de la imagen desde una perspectiva semiótica.

SemiòticaIl·lustracions imatges etc. Interpretació

Etilics i irresponsables

1986

Vida y costumbresProhibiciónUNESCO::HISTORIA::Historia por épocas::Historia antiguaCafé:HISTORIA::Historia por épocas::Historia antigua [UNESCO]ConsumoBebidas alcohólicas

Biometrical and Biological Considerations on the Cory’s Shearwater Calonectris Diomedea

1986

Today the Mediterranean distribution of Cory’s Shearwaters is believed to be well known. New colonies may be discovered, but certainly the largest ones are known. Many data were published during the last ten years and we believe to have a satisfactory knowledge of their biology, though some problems, as the winter movements of each population, the first breeding age and the ratio immatures/adults are still to be examined carefully.

Mediterranean climateeducation.field_of_studyCalonectris diomedeaGeographybiologyPopulationZoologyCory's shearwaterbiology.organism_classificationeducation

Cyclometallation reactions in complexes of the type Rh(oq)(CO)(P(o-BrC6F4)Ph2)

1986

Abstract The reaction of Rh(oq)(CO)(PCBr) (PCBr = P(o-BrC6F4)Ph2; oq = 8-oxyquinolinte)_ in refluxing toluene in the presence of Et4NBr (1/4 molar ratio) gives Rh(oq)Br(PC) (H2O), PC = P (o-C6F4)Ph2, in practically quantitative yield. The water molecule is readily displaced by various P-donor ligands to give complexes of general formula Rh(oq)Br(PC) PR3 (PR3 = PPh3, P(p-MeC6H4)3, P(p-MeOC6H4)3, P(p-FC6H4)3, P(PMe)3 and P(OPh3). The molecular structure of the compound Rh(oq)Br(PC) (PPh3) has been determined by X-ray methods. Crystals of the title compound are monoclinic, space group P21/n with unit cell dimensions a 11.273(4), b 20.087(8), c 17.471(7) A and β 102.15(8)°. The final R for 2304…

StereochemistryOrganic Chemistrychemistry.chemical_elementBiochemistryTolueneRhodiumInorganic ChemistryBond lengthchemistry.chemical_compoundCrystallographychemistryOctahedronYield (chemistry)Materials ChemistryMoleculePhysical and Theoretical ChemistryPhosphineMonoclinic crystal systemJournal of Organometallic Chemistry

Acanthochaetetidae (Hadromerida, Demospongiae) fromthe Coniacian of Vera de Bidasoa (basque pyrénées, Northern Spain)

1986

Abstract Acanthochaetetes specimens from the Coniacian brecciated limestones near Vera de Bidasoa (Northern Spain) are described. It is the first report of acanthochaetetids from Coniacian strata. The specimens are very small and probably lived in fissures and crevices in fore-reef breccias and deep water mud mounds. The family Acanthochaetetidae Fischer is placed in the order Hadromerida (Tetractinomorpha, Demospongiae). The order Tabulospongida Hartman & Goreau was abandoned.

PaleontologybiologySpace and Planetary ScienceBrecciaPaleoecologyAcanthochaetetesPaleontologybiology.organism_classificationHadromeridaGeologyTetractinomorphaAcanthochaetetidaeDeep waterGeobios

Mechanismus und Reaktionswege der Xanthenylierung an ambidenten nukleophilen Arzneistoffen

1986

Am Beispiel der ambidenten nukleophilen Arzneistoffe 4-Aminobenzolsulfonamid (3), Indometacin (7) und Phenylbutazon (10) werden Aralkylierungen mit dem SN1-aktiven Reagens Xanthydrol (1) vorgestellt. Mechanism and Reaction Path of the Xanthenylation of Ambident Nucleophilic Drugs The aralkylation of ambident nucleophilic drugs, e.g. 4-aminobenzenesulfonamide (3), indometacine (7) and phenylbutazone (10), with SN1-active xanthydrol (1) is described.

chemistry.chemical_classificationchemistry.chemical_compoundSN1 reactionNucleophileBicyclic moleculechemistryStereochemistryDrug DiscoveryPharmaceutical ScienceReaction pathXanthydrolSulfonamideArchiv der Pharmazie

Über polygermane

1986

Abstract The synthesis of GePh4 and Ge2Ph6 by Grignard reaction in THF or ether/toluene leads to the by-products Ge3Ph8 (up to 11%) and Ge4Ph10 (up to 18%) which is dependant on using an excess of Mg. A quantitative analysis of the resulting products by HPLC and a semipreparative separation by column, flash, and HPL chromatography is described. The crystal structures of Ge3Ph8 (R = 0.075) and Ge4Ph10 · 2C6H6 (R = 0.054) have been determined. Ge4Ph10 has Ci symmetry and both chain conformations are well staggered (49–70° for Ge3Ph8, 53–66° for Ge4Ph10). The GeGe distances and GeGeGe angles are 244 pm and 121° (Ge3Ph8), and 246 pm and 118° (Ge4Ph10).

ChemistryStereochemistryOrganic ChemistryGrignard reactionEtherNuclear magnetic resonance spectroscopyCrystal structureBiochemistryMedicinal chemistryTolueneHigh-performance liquid chromatographyInorganic Chemistrychemistry.chemical_compoundX-ray crystallographyMaterials ChemistryMoleculePhysical and Theoretical ChemistryJournal of Organometallic Chemistry

Reacciones emocionales en pacientes con cáncer de mama : patrones emocionales en grupos criterio y grupos normales

1986

Psychology Clinical:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍA