Complement receptors on lymphocytes

1981

High-performance liquid chromatography of trichothecenes

1981

Acid hydrolase activities in mouse cardiac and skeletal muscle following exhaustive exercise

1981

Acid hydrolase activities in skeletal and cardiac muscle were studied 5, 10 and 20 days after exhaustive intermittent running by untrained and endurance-trained mice. Exhaustion increased the activities of cathepsin D, beta-glucuronidase and ribonuclease, but not that of p-nitrophenylphosphatase in skeletal muscle of untrained mice. Activities were highest on the fifth day after exhaustion and decreased during the following two weeks. More intensive loading produced no changes in acid hydrolytic capacity in skeletal muscle of endurance-trained mice. Acid hydrolase activities in cardiac muscle of both untrained and trained mice were unaffected by exhaustive running. It is suggested that exha…

Simulation and Parameter-Identification of the Closed-Loop Cardiovascular System by the Use of a Nonlinear Mathematical Model

1981

Abstract A non-linear model of human cardio-vascular system, which includes the short-term pressure regulation mechanism was mathematically derived and implemented on a PDP-11/45 in a block-oriented, interactive programming language. In this way the behaviour of the arterial and venous pressures, cardiac output, stroke volume, total peripheral resistance and heart-rate under ergometric workload was studied by simulation, and experimentally proved, that the model matches the system with good accuracy. In a second phase the parameters of the model were identified by the use of the output-error method. For this purpose a non-linear system identification programming package was applied. The par…

Beam optics and magnet technology of the microtron in mainz

1981

Abstract A description is given of the beam transport system for injection into the first microtron of MAMI. Further, a special procedure to improve the field distribution of the dipole magnets is described in some detail and results are given.

Electrical responses of pineal cells to melatonin and putative transmitters

1981

The effects of microelectrophoretically applied melatonin (N-acetyl-5-methoxy-tryptamine), noradrenaline (NOR) or acetylcholine (ACH) on the electrical activity of pineal cells during both the day- and night-time were studied in urethane anesthetised guinea-pigs. A total of 288 cells were tested with melatonin, and in addition with either NOR (120 cells) or ACH (138 cells). Of the 206 cells responding to melatonin application, 139 were excited and 67 inhibited. A total of 85 cells responded to the application of NOR, 45 being excited and 40 inhibited. Responses to ACH application were observed in 75 pineal cells, 49 units being inhibited and 26 excited. It was possible to observe excitation…

Zum Ursprung der Hominidae

1981

A fundamental problem of hominisation is the branching of the human lineage leading to the genusHomo from other hominoids. At present discussed hypotheses of a Miocene separation of the pongid and hominid lineage are described under consideration of numerous new fossils from Europe, Asia and Africa. Of special interest is the possibility of an adhominisation of the genusAustralopithecus (includingA. afarensis).

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981

The site of action of the immunosuppressive drug cyclosporin A in in vitro cytotoxic allograft responses has been localized. General cytotoxic effects of the drug on proliferating T cells became apparent at concentrations of 500-1000 ng/ml, while selective effects were observed at concentrations of 10-100 ng/ml. The selective effects included a blockade of interleukin 2 release from activated T helper cells on the one hand and inhibition of interleukin 1 release from splenic adherent cells on the other. While cyclosporin A did not interfere with the intracellular events required for the activation and subsequent clonal expansion of alloreactive T cells, the lack of interleukin 1 and interle…

Complexes of tungsten (VI) with tartaric acid. Comparative study of the various schemes of formation

1981

The complex formation occurring between tungstic acid and tartaric acid has been investigated in order to explain the optical activity of tartaric acid in the presence of constant amounts of tungstic acid. A new scheme of formation that includes three different complexes is presented, which explains the experimental results found in the literature.

Analysis of the $$\pi ^ + p$$ radiative scattering below the $$\Delta ^{ + + } \left( {1232} \right)$$ -resonance.

1981

Gas-liquid chromatographic analyses of chlorination products of propionyl chloride

1981

Abstract Photochlorination of propionyl chloride with chlorine in the liquid phase at room temperature gives all eleven chloropropionyl chlorides from the mono-to the pentachloro isomer. The process was investigated every 2 h by gas-liquid chromatography, and the products were identified and estimated as their methyl esters by comparison with model compounds. The isomer distribution of the products was studied in detail. Because the process favours the 3-position, the main components were 3-chloropropionyl chloride up to 15 h, 3,3-dichloropropionyl chloride between 15 and 29 h, 3,3,3-trichloropropionyl chloride between 29 and 56 h and pentachloropropionyl chloride after 56 h of chlorination.

A fifth class of antiarrhythmic action?

1981

A negative inotropic effect of acetylcholine in the presence of several phosphodiesterase inhibitors.

1981

The phosphodiesterase inhibitors papaverine, theophylline and 3-isobutyl-1-methylxanthine (IBMX) reveal a negative inotropic effect of acetylcholine in cat ventricular heart muscle. This effect in unrelated to beta-adrenoceptor stimulation and possibly mediated by the accumulation of cyclic GMP.

WEAK INTERACTIONS, SYMMETRIES

1981

Abstract The Standard ideas about the breaking of symmetries, through the mechanism of generation mixing, are discussed. New results and proposals looking for discrete space-time symmetry violation as well as flavour-number violation are reported. The use of weak-interaction processes as a tool for both the study of the structure of the currents and for nuclear-structure problems is emphasized.

Trapped ion density distribution in the presence of He-buffer gas

1981

The spatial density distribution of Ba+ ions, confined in a rf quadrupole trap, has been measured by laser scanning across the trap. This allows to determine the ion temperature, assuming thermal equilibrium. Under UHV conditions the average ion energy has been found to be one tenth of the trap potential well depth. Collisions with He at pressures up to 5×10−6 mbar reduce the ion temperature by a factor of 3.

The effects of equal caloric amounts of xylitol, sucrose and starch on insulin requirements and blood glucose levels in insulin-dependent diabetics

1981

Xylitol has been suggested as a potentially useful sweetener in the diabetic diet. In 14 insulin-dependent diabetics a standard diabetic diet regimen was compared with diets in which starch was isocalorically exchanged in the breakfast meal by either 30 g xylitol or 30 g sucrose. Insulin requirement and blood glucose were measured using a glucose-controlled insulin infusion system. The results following breakfast with xylitol were similar to those after starch breakfasts. Sucrose, in contrast, induced a greater post-prandial rise in blood glucose levels despite counter-regulation by the glucose-controlled insulin infusion system. Insulin requirement after sucrose significantly exceeded (p l…

Performance of the on-line isotope separation facility HELIOS at the Mainz reactor

1981

Abstract The helium-jet on-line isotope eparation facility HELIOS is in operation at the Mainz reactor for spectroscopic studies on mass separated neutron-rich nuclides far from the line of beta-stability. The basic features and achievements of the facility are reported. A total of 45 isotopes of the elements Rb, Sr, Y, Sn, Sb, Te, Cs, Ba, La, Ce, Pr and Nd have been separated and identified so far. Overall efficiencies up to 2% have been obtained using the integrated skimmer ion source arrangement either in a hollow cathode or in a high temperature surface ionization mode. The delay time for the HELIOS system was determined to be about 1 s.

Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy

1981

The incidence of bacteremia following proctoscopy and hemorrhoidal injection sclerotherapy was studied in 50 outpatients undergoing both procedures. Bacteremia was found in 2 per cent of the subjects after proctoscopy and in 8 per cent after sclerotherapy. None of the subjects developed symptoms of septicemia following the procedure. It is concluded that antibiotic prophylaxis should be used before sclerotherapy in patients with valvular heart disease or compromised host defense.

Malignant fibrous histiocytoma of the renal capsule

1981

We report about an extremely rare case of malignant fibrous histiocytoma (MFH) of the renal capsule. The tumor is composed of fibroblast-like cells arranged in a storiform pattern and histiocyte-like cells with multinucleated giant cells, both showing no iron reaction. Characteristic of the histiocytic quality of the tumor are numerous PAS-positive intracytoplasmic droplets which can be identified as erythrophagosomes only under the electron microscope. Emphasis is put on the preoperative differential diagnosis of the tumor from renal cell carcinoma as well as on its histogenesis and prognosis.

Observation of beta-delayed neutron decay to excited 0+ states in the residual nucleus: The case

1981

Abstract Beta-delayed neutron emission from 97 Rb to excited 0 + states in 96 Sr has been observed. The experimental branching ratios ( P n i ) are compared to predictions from a statistical model. It is demonstrated that, considering the influence of the strength of β -decay preceding neutron emission, the ( P n i ) reflect the different structure of the two excited 0 + states, in agreement with conclusions drawn from the measurement of their lifetimes.

Phasenumwandlungen in Korrosionsschichten auf Eisen: Mößbauerspektroskopische Untersuchungen

1981

Zur Untersuchung der Korrosion von Stahlblechen wurde die mosbauerspektroskopische Phasenanalyse in Transmissions- und Streugeometrie eingesetzt. Die Korrosion von Stahlblechen fuhrt in einer Atmosphare von geringer Korrosivitat nach langen Expositionszeiten vorwiegend zu den relativ stabilen β-Phasen der moglichen Fe-Korrosionsprodukte. Bei durch HCl-Zusatz erhohter Korrosivitat ergibt sich eine Bevorzugung der Bildung von β-FeOOH und kein Auftreten der α-Phasen. Auch der Einflus von. Beschichtungen auf die Phasenzusammensetzung wird behandelt. Die Entstehung und Umwandlung der verschiedenen Fe-haltigen Phasen im Rost last sich anhand eines Stabilitatsdiagramms verstehen. Auch die Wirkung …

A study of a helium-jet ion guide for an on-line isotope separator

1981

Abstract A new method based on helium-jet techniques permits primary recoil ions, produced in radioactive decay or in nuclear reactions to be run directly through a mass separator. Results obtained with a 227 Ac source promise qualities complementary with those obtained with conventional ion sources and indicate an overall efficiency of the order of 10%. Preliminary results with 20 Na recoils from the 20 Ne(p,n)-reaction indicate that most of the ionic species transported out from the target chamber are negatively charged.

The glass transition behaviour of salted nylon 6

1981

Glass transition measurements of nylon-6/lithium halides mixtures have been carried out in wide range of frequency with the aid of different experimental techniques. The results show an increase of the glass transition temperature when the salt is present and prove the larger effectiveness of lithium chloride with respect of lithium bromide. This effect, in line with the large reduction of the specific volume caused by the salt, is due to the formation of a pseudo-cross-linking between lithium ions and the carbonyl-oxygen groups of the polyamide.

Unerwartete metabolische Azidose bei schwerer Lauge-Intoxikation

1981

Bei einer 38jahrigen Patientin mit einer schweren peroralen Lauge-Intoxikation ohne Schock entwickelte sich trotz Substitutions-Therapie eine uber 8 Tage andauernde metabolische Azidose. Die metabolische Azidose wurde durch eine Akkummulation von Milchsaure verursacht. Die gesteigerte Laktatproduktion in den Randbezirken veratzter Areale des Verdauungstrakts sowie ein gestorter hepatischer Laktatabbau sind mit groser Wahrscheinlichkeit fur die Laktazidose bei Lauge-Intoxikation verantwortlich.

Time-related changes in size of nuclei of pinealocytes in rats

1981

In a study of 96 adult male Sprague-Dawley rats, da- and time-related changes of the mean nuclear volume of pinealocytes were determined with the aim of testing the reproducibility of the karyometric findings described by Quay and Renzoni (1966). It is shown (i) that statistically significant differences exist between the central and peripheral mean volumes of pinealocyte nuclei/group of animals and time point (p less than 0.001), (ii) that the day and time related differences are statistically different in both regions (p less than 0.001), (iii) that in the center and periphery of the pineal body different diurnal patterns exist, and (iv) that the diurnal patterns are not parallel in the t…

High voltage stabilisation for an on-line isotope separator

1981

Abstract Stabilisation for a high voltage generator up to 60 kV has been developed. The voltage is stable within ±0.1 V. This allows the very accurate acceleration of charged particles.

Besançon: micro-informatisation du fichier d'accidents de circulation

1981

International audience

Separation of left atrium from right pulmonary artery: a new echocardiographic sign of pericardial effusion.

1981

We report a new echocardiographic sign of pericardial effusion in patients with pericardial effusion examined by the suprasternal approach. In normal individuals the right pulmonary artery is closely connected with the superior wall of the left atrium. A separation of these structures is only to be noticed during atrial contraction. In 12 of 17 patients with a pericardial effusion observed a separation of the left atrium from the right pulmonary artery ranging from 3 to 20 mm throughout the cardial cycle. We suggest that this echo-free zone represents fluid in the transverse pericardial sinus which is located between the two structures. In five patients with a small pericardial effusion (le…

Significance of hyperlactatemia in acute hypnotic drug poisoning

1981

Lactate concentration, fibrinogen and fibrin(ogen) -- degradation-products in central venous blood were analysed in 35 unconscious patient with acute hypnotic drug poisoning (HDP) and compared with the results in 13 healthy control persons undergoing the same degree of forced diuresis via central venous catheters. Blood samples were taken on admission and at 12 h intervals up to 36 h after admission. Patients with HDP were attributed to the categories of moderate intoxications (n = 17) and severe intoxications (n = 18) according to their clinical condition. On admission, blood lactate was significantly higher in severe intoxication (3.90 +/- 2.94 mmol/l) as compared to the control group (1.…

Magnesium concentration in saliva — an indicator of digitalis toxicity

1981

In a prospective study salivary magnesium was measured by atomic absorption spectrophotometry in 168 patients on chronic digoxin therapy. Magnesium concentration in saliva was correlated with clinical data and plasma digoxin levels. A significant elevation in salivary magnesium concentration was caused by digoxin therapy (0.58 +/- 0.39 mmol/l, n = 93) in comparison to patients with no digitalis treatment (0.17 +/- 0.07 mmol/l, n = 35). Magnesium concentrations in saliva were significantly higher in toxic patients (1.1 +/- 0.68 mmol/l, n = 32) than in nontoxic patients. Possibly toxic patients showed a magnesium level of saliva of 0.63 +/- 0.39 mmol/l (n = 40). In 89% of the intoxicated pati…

The reconstitution of human C1, the first complement component Binding of C1r and C1s to C1q influences the C1q conformation

1981

Chemie an starren Grenzflächen, 6 Photochemisch induzierte Reaktionen mit grenzflächengebundenen Sensibilisatoren

1981

Aerosil® wird mit 3-Triethoxysilylpropylamin zu Aminoaerosil(1) umgesetzt und dieses mit carboxylgruppenhaltigen Sensibilisatoren in die grenzflachenmodifizierten Aerosile2a-f ubergefuhrt. Die Beladungsdichte mit funktionellen Gruppen, die nach unterschiedlichen Methoden bestimmt wird, beeinflust maβgebend das Reaktionsergebnis. Bei der Bestrahlung der grenzflachenmodifizierten Aerosile2a - c in Isopropylalkohol entstehen Aceton sowie das grenzflachengebundene Pinakol, z. B.4, das mit Bleitetraacetat wieder zu2b ruckoxidiert werden kann. Die Hydrodimerisierung an der Grenzflache von2b lauft 3mal langsamer als mit der Analogverbindung im Homogensystem. Bei der Photoreduktion von2b geringer B…

Precambrian crustal evolution and continental drift

1981

One of the major questions of Precambrian research is whether present-day plate tectonic models can be applied to the evolution of the ancient continental crust or whether the tectonic style suggests a unidirectional and therefore non-uniformitarian development in response to gradual changes in the global thermal regime through time.

Quantifizierung des coronaren Befallsmusters mit Hilfe einer computergestützten Analyse multipler EKG-Parameter

1981

Coronarangiogramme von 200 Patienten mit koronarer Herzkrankheit wurden untersucht. Die Analyse bezieht sich auf die Verteilung der Stenosen in den verschiedenen Gefasabschnitten des Coronarsystems. Mit Hilfe eines speziellen Score's wird Versorgungstyp, Stenosegrad, Lokalisation und Kollateralisation in einem Zahlenwert erfast. Andererseits sind von diesen Patienten Frank-Elektrokardiogramme computermasig erfast und quantifiziert. Zur Auswertung kommen 140 skalare und vektorielle Parameter. Verglichen wird eine Gruppe von 36 Patienten mit umschriebenen Stenosen im Bereich des Ramus interventrikularis anterior mit 37 Untersuchten, die keine Stenosierungen aufweisen.

The decay modeτ→πων τ and second class currents

1981

Predictions of a set of equal-time commutators between first and second class currents for the decayτ→πωντ are discussed. Such experiment should be feasible with the present detectors at SPEAR/PEP and DORIS/PETRA.

Der austausch des cyclopentadienylliganden im methylcyclopentadienyl-mangantricarbonyl

1981

Abstract The exchange of the cyclopentadienyl ring in methylcyclopentadienylmanganese(I) tricarbonyl by methy-substituted benzenes in the presence of aluminium halide leads to [arene-Mn(CO) 3 ] + -ions. The reaction conditions have been optimised; in addition to the yield the purity of the complexes has been determined in some detail. After mild decomposition the arenes were analysed by GLC. Pure [arene-Mn(CO) 3 ] + -ions can be isolated with benzene, toluene, m - and o -xylene.