Phosphatidylcholine-Gramicidin a Interaction Study in Non-Aqueous Solvent with a new HPLC-SEC Column

1985

Abstract A new HPLC-SEC column, Ultrastyragel 500 A, has been assayed in order to check the separation between gramicidin A and phosphatidylcholine in tetrahydrofuran. The good resolution of both compounds has allowed the quantitation of lipid-polypeptide interaction in terms of the binding ratio parameter, BR. A BR value of 3.6 moles of phosphatidylcholine per mole of gramicidin A has been obtained for a 0.1 % (w/v) phosphatidylcholine solution as eluent. The suitability of this support for studies on lipid-polypeptide interactions in non-aqueous solvents is demonstrated.

The image of the smoking and non-smoking young person

1985

MORE than 1,600 Finnish secondary school pupils between the ages of 12 and 16 completed a question naire about their image of the smoking and non- smoking adolescent. A smoker was described as nervous, unfriendly, untidy, stupid and a low achiever in sport and academic work, but despite this, was seen as a leader. Non-smokers were seen as calm, strong, fairly modest, friendly, tidy and smart, but not as leaders. Older pupils saw the smoker in a more positive light. Those who smoked saw the non- smoker image as positive, and rated the smoking image more highly than did non smokers.

Effect of verapamil and diltiazem on isolated gastro-oesophageal sphincter of the rat

1985

Abstract The effect of verapamil and diltiazem on the contraction induced by agonists on the rat lower oesophageal sphincter in-vitro has been studied. Both calcium entry blockers inhibited the contractile response to acetylcholine, carbachol and KCl. The potency of the inhibitory action was diltiazem > verapamil. The results give substance to the use of calcium entry blockers in the treatment of oesophageal spasm.

An ultraviolet receptor as a fourth receptor type in goldfish color vision

1985

Nuclear charge radii of the even sulphur isotopesS32,S34, andS36and ofP31using muonic atoms

1985

Energies of muonic x rays of the Lyman series of the even sulphur isotopes /sup 32/S, /sup 34/S, and /sup 36/S and of natural phosphorus have been determined with absolute precisions up to 23 parts/10/sup 6/. Equivalent Barrett charge radii R/sub k/,..cap alpha.. have been deduced. Their differences between the sulphur isotopes amount to ..delta..R/sub k/,..cap alpha..( /sup 34/S- /sup 32/ S) = 29.7(1.4) am and ..delta..R/sub k/,..cap alpha..( /sup 36/S- /sup 34/ S) = 18.7(1.5) am. Combining these results with recent elastic electron scattering data, we obtain in a model-independent way ..delta../sup 1/2/( /sup 34/S- /sup 3/ 2S) = 23.1(1.2) am and ..delta../sup 1/2/( /sup 36/S- /sup 3/ 4S) …

Stereoselective glycosylation of Alcohols and Silyl Ethers Using Glycosyl Fluorides and Boron Trifluoride Etherate

1985

The stereoselective glycosylation of alcohols and their silyl ethers has been achieved using O-alkyl-, O-acyl-, and acetal-protected glycosyl fluorides of the pyranose and furanose series and boron trifluoride etherate in CH2Cl2.

Chemoselektive Fluoreszenzstudien am Subtilisin und “Thiosubtilisin”

1985

Chemoselective Fluorescence Studies with Subtilisin and “Thiosubtilisin” The serine hydroxy group in the active site of subtilisin is selectively “phosphylated”3). This is demonstrated using the fluorescent phosphinic fluoride 1. “Thiosubtilisin” does not react with 1 but with the SH-selective and fluorescent vinyl sulfone 2.

Optimisation de la combinaison des facteurs de quantité et de qualité en éducation : quelques arbitrages qui valent d'être considérés

1985

International audience

Attempts to Produce Superheavy Elements by Fusion ofCa48withCm248in the Bombarding Energy Range of 4.5-5.2 MeV/u

1985

A search for superheavy elements was made in bombardments of $^{248}\mathrm{Cm}$ with $^{48}\mathrm{Ca}$ ions performed at projectile energies close to the interaction barrier in order to keep the excitation energy of the compound nucleus $Z=116$, $A=296$ as low as possible. No evidence for superheavy nuclei was obtained in a half-life region from 1 \ensuremath{\mu}s to 10 yr with a production cross section greater than ${10}^{\ensuremath{-}34}$ to ${10}^{\ensuremath{-}35}$ ${\mathrm{cm}}^{2}$.

Affinity and efficacy of racemic, (+)-, and (−)-methacholine in muscarinic inhibition of [3H]-noradrenaline release

1985

The right postganglionic sympathetic nerves of rat isolated perfused hearts (previously loaded with [3H]-noradrenaline) were stimulated electrically with 10 trains of 10 pulses at 10 Hz. The inhibition by methacholine of stimulation-evoked [3H]-noradrenaline overflow into the perfusate (determined in the presence of corticosterone, desipramine, phentolamine, and propranolol) was taken as a measure for activation of presynaptic muscarinic receptors. The evoked [3H]-noradrenaline overflow was inhibited by (+)-, racemic, and (-)-methacholine in a reversible and concentration-dependent manner. The concentration causing 50% inhibition (IC50) was 0.1, 0.26, and 65 microM, respectively, resulting …

Serum hormones during prolonged training of neuromuscular performance.

1985

The effects of a 24-weeks' progressive training of neuromuscular performance capacity on maximal strength and on hormone balance were investigated periodically in 21 male subjects during the course of the training and during a subsequent detraining period of 12 weeks. Great increases in maximal strength were noted during the first 20 weeks, followed by a plateau phase during the last 4 weeks of training. Testosterone/cortisol ratio increased during training. During the last 4 weeks of training changes in maximal strength correlated with the changes in testosterone/cortisol (P less than 0.01) and testosterone/SHBG (P less than 0.05) ratios. During detraining, correlative decreases were found…

Persistence of Antibodies to Rickettsia conorii After an Acute Attack of Boutonneuse Fever

1985

La formation du capital et le financement de l'amortissement chez Walras et Keynes

1985

L'explication de la formation du capital dans les systèmes de Walras distingue les entrepreneurs des capitalistes. Les premiers organisent la production, les seconds épargnent une partie de leur revenu tiré de la rémunération des services producteurs. Walras distingue essentiellement trois facteurs de production, le travail, la terre et le capital. (...)

Investigations of polymerizable multilayers as gas separation membranes

1985

Abstract Polymerizable Langmuir—Blodgett (LB) multilayers of several diacetylenic amphiphiles were investigated on gas-permeable, polymeric supports. Macroscopically homogeneous multilayer films of hexacosa-10,12-diynoic acid and pentacosa-10,12-diyne phosphonate could be built up on polypropylene and polytetrafluoroethylene materials. As shown by scanning electron microscopy, the microscopic homogeneity of the built-up multilayers was mainly controlled by the surface structure of the support material, whereas the chemical nature of the support and photopolymerization of the layers did not affect the high order of the films. Such LB multilayers deposited on porous support materials are able…

IL TRICOBEZOARIO IN ETA' PEDIATRICA: DESCRIZIONE DI UN CASO A LOCALIZZAZIONE GASTRICA

1985

Gli Autori riferiscono su di un caso di tricobezoario a localizzazione gastrica, sottolineando l'iter diagnostico e l'importanza della valutazione ecografica ed endoscopica.

Financement de l'enseignement en Afrique francophone (1- financement et politique de l'éducation, 2- Modalité de financement de l'enseignement supéri…

1985

référence interne : 85023

Spatial development of multiple-gap states in nonequilibrium superconductors

1985

We have studied the gap instability in a superconductor under tunneling injection at high voltages by probing the spatial distribution of the phonon emission. A high sensitivity was achieved by using the fountain pressure of superfluid helium for detecting the phonons. Spatial structures were observed at gap depressions as small as 2%. From their spatial development we find that the quasiparticles diffuse into regions where their density is higher.

Hypolaetin-8-O-Glucoside, An Anti-inflammatory Flavonoid from Sideritis mugronensis.

1985

Finite-size tests of hyperscaling.

1985

The possible form of hyperscaling violations in finite-size scaling theory is discussed. The implications for recent tests in Monte Carlo simulations of the d = 3 Ising model are examined, and new results for the d = 5 Ising model are presented.

Phosphororganische Verbindungen, 111. Phosphin‐ und Thiophosphinsäure‐cyanide als fluoreszierende SH‐selektive Reagenzien

1985

Die fluoreszierenden Thiophosphinsaure-cyanide 7 und 8 sind SH-selektive, die analogen Thio-phosphinsaure-chloride 5 und 6 sind im allgemeinen NH2-selektiv (Ausnahme: Cystein-methylester, der S-thiophosphinoyliert wird). Die auf diesem Wege erhaltenen fluoreszierenden Dithio-phosphinsaureester, z.B. 11–14, sind fur die Analyse interessant. Durch Fluorolyse der Dithio-phosphinsaureester konnen die Thiole regeneriert werden. Diphenylthiophosphinsaure-cyanid verdient als SH-selektive Schutzgruppe fur Synthesen den Vorzug vor 7 und 8. Organophosphorus Compounds, 111 Phosphinic and Thiophosphinic Cyanides as Fluorescent SH-selective Reagents The fluorescent thiophosphinic cyanides 7 and 8 are SH…

A search for short-period pulsars

1985

On utilise le radiotelescopede Parkes pour rechercher des pulsars de courte periode a 1,4 GHz de frequence. On trouve quatre nouveaux pulsar radio

Complexes of organometallic compounds. LI. The correlation between 119Sn Mössbauer isomer shifts and partial atomic charges on tin in R3SnL compounds

1985

Abstract The 119Sn Mossbauer isomer shift parameters, δ, of compounds R3SnL (R = AlK, Ph; L = F, Cl, OH, OR′, CN, NCS, NCO, N3) have been correlated to partial atomic charges on tin QSn, calculated according to a valence state electronegativity equalization procedure carried out by the CHELEQ program. A unique δ/QSn correlation has been obtained for all the five-coordinated R3SnL species by using average δ parameters for the AlK3IV derivatives.

Approche empirique de la notion de centralité urbaine : le cas de l'agglomération dijonnaise

1985

L'analyse spatiale urbaine définit la ville comme un centre économique: centre de marché pour l'arrière pays rural dans le cas de la ville Thlinienne, centre de la région sur laquelle elle étend son influence dans le cas de la ville loschienne ; cette ville-centre est, le plus souvent,considérée comme ponctuelle. Peu d'études sont consacrées par les économistes au centre de la ville. Plus qu'objet d'analyse, celui-ci apparaît comme simple outil des modèles d'analyse spatiale ; ses propriétés résultent de la transposition de celles de la ville-centre : il est donné a priori, et considéré comme ponctuel ; il est le centre du marché urbain ; enfin, sa structure interne échappe à l'analyse urba…

Cotas inferiores para el QAP-Arbol

1985

The Tree-QAP is a special case of the Quadratic Assignment Problem where the flows not equal zero form a tree. No condition is required for the distance matrix. In this paper we present an integer programming formulation for the Tree-QAP. We use this formulation to construct four Lagrangean relaxations that produce several lower bounds for this problem. To solve one of the relaxed problems we present a Dynamic Programming algorithm which is a generalization of the algorithm of this type that gives a lower bound for the Travelling Salesman Problem. A comparison is given between the lower bounds obtained by each ralaxation for examples with size from 12 to 25.

Comparison of the exoproducts of gram-negative bacteria by SDS-page

1985

The protein exoproducts released during exponential growth of Gram-negative bacteria were analysed and compared by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-Page). The following bacterial strains were tested: Escherichia coli, Klebsiella pneumoniae, Citrobacter freundii, Enterobacter cloacae, Serratia liquefaciens, Serratia rubidaea, Proteus mirabilis, Proteus vulgaris, Salmonella minnesota, Pseudomonas aeruginosa and Pseudomonas fluorescens. It is demonstrated by SDS-Page that members of one species show identical protein pattern, whereas different species show besides comparable protein bands a species characteristic pattern. All members of Enterobacteriaceae were sho…

Ultrastructural study of primary canine and human pigmentary retinopathy

1985

An electron microscopic study was performed on eyes of Labrador dogs afflicted with progressive retinal atrophy (PRA). There was complete loss of photoreceptors, atrophy of the remaining retina and gliosis in the peripheral part while the central retina showed incomplete loss of photoreceptors and an almost total disappearance of photoreceptor outer segments. Melanin-bearing cells, largely containing melanolysosomes, were found deep inside the retina. This electron microscopic study also incorporated the retina of a middle-aged woman affected by retinopathia pigmentosa (RP). The fine structure of the diseased retina showed a similar pattern of lesions, more pronounced in the periphery of th…

Hand-arm vibration and the central nervous system

1985

Ejection and collision orbits of the spatial restricted three-body problem

1985

We begin by describing the global flow of the spatial two body rotating problem, μ=0. The remainder of the work is devoted to study the ejection and collision orbits when μ>-0. We make use of the ‘blow up’ techniques to show that for any fixed value of the Jacobian constant the set of these orbits is diffeomorphic to S2×R. Also we find some particular collision-ejection orbits.

Antineoplastika XVI [1]. 4-Alkyl-6-trifluormethyl-2-ureidopyrimidine

1985

Zusammenfassung Bei der Umsetzung von Dicyandiamid mit Trifluormethyl- gruppen tragenden β-Diketonen entstehen die korrespondierenden 4-Alkyl-6-trifluormethyl-2-ureidopyrimidine. So wird mit 1,1,1-Trifluor-2,4-pentandion das 4-Methyl-6-trifluormethyl- 2-ureidopyrimidin, mit 1,1,1-Trifluor-2,4-hexandion das 4- Ethyl-6-trifluormethyl-2-ureidopyrimidin, erhalten. Die Struktur der Endprodukte wird dutch die IR-, 1 H-NMR-, 13 C-NMR- und Massenspektren charakterisiert.

Positron studies of hydrogen-defect interactions in proton irradiated molybdenum

1985

Molybdenum single crystals are irradiated at 20 K with 6 MeV protons. The radiation damage and lattice defect annealing is studied by positron lifetime spectroscopy in the temperature range from 15 to 720 K. Loss of vacancies due to recombination with mobile interstitials is observed at 40 K (Stage I) in agreement with resistivity measurements. This is the first time Stage I is observed by positrons below 77 K. The implanted hydrogen decorates the vacancies around 100 K, which is consistent with a hydrogen migration energy in molybdenum:E H = 0.3–0.4 eV. Clustering of spatially correlated vacancies takes place in a wide temperature region below the usual vacancy clustering stage (Stage III)…

SU DI UN CASO DI NEFROMA MESOBLASTICO DEL NEONATO

1985

Gli Autori descrivono un caso di Nefroma Mesoblastico del neonato evidenziando i problemi di diagnostica differenziale e di approccio terapeutico.

Exhaust Pipe Design Method for the Optimization of the Scavenging Process

1985

Conception des tuyauteries d'echappement en vue d'optimiser le balayage dans un moteur deux temps

Geochemical characteristics of Archaean and Late Proterozoic to Palaeozoic fine-grained sediments from Southern Africa and significance for the evolu…

1985

Chemical data for pelitic rocks (shallow-marine platform sediments) of the ∼ 2.9 Ga old Pongola Supergroup, South Africa, and the 550–700 Ma old Nama Group, Namibia, revealed clearly different compositions in both groups. A comparison of the Pongola and Nama data with literature values for sedimentary rocks shows a trend for Cr/TiO2 and Cr/Zn ratios as well as the absolute Cr and Ni concentrations to lower values with decreasing age, whereas the Cr/Ni ratios seem to remain broadly constant through time. REE patterns of Pongola and Nama sediments show no significant difference, thus giving the impression of a post-Archaean origin for the demonstrably Archaean Pongola sediments. However, a pl…

Cohomology, central extensions, and (dynamical) groups

1985

We analyze in this paper the process of group contraction which allows the transition from the Einstenian quantum dynamics to the Galilean one in terms of the cohomology of the Poincare and Galilei groups. It is shown that the cohomological constructions on both groups do not commute with the contraction process. As a result, the extension coboundaries of the Poincare group which lead to extension cocycles of the Galilei group in the “nonrelativistic” limit are characterized geometrically. Finally, the above results are applied to a quantization procedure based on a group manifold.

Le coût des formations aux professions de la santé : le cas des établissements de Dijon et de Beaune

1985

référence interne : 85016; La présente étude a pour but d'évaluer le coût de la formation de quatre professions de la santé : médecins, pharmaciens, infirmier(e)s, sages-femmes. Elle porte sur des établissements localisés à Dijon, ainsi que sur une école d'infirmière de Beaune.

Deuteron n.m.r. in relation to the glass transition in polymers

1985

Abstract 2H n.m.r. is introduced as a tool for investigating slow molecular motion in the glass transition region of amorphous polymers. In particular, we compare 2H spin alignment echo spectra of chain deuterated polystyrene with models for restricted rotational Brownian motion. Molecular motion in the polystyrene-toluene system has been investigated by analysing 2H n.m.r. of partially deuterated polystyrene and toluene, respectively. The diluent mobility in the mixed glass has been decomposed into ‘solid’ and ‘liquid’ components where the respective average correlation times differ by more than 5 decades.