Oxygen Transport in Tumors

1996

Experimental evidence suggests that the hypoxic fraction in solid tumors may influence its growth, may increase its malignant potential, and may reduce its sensitivity towards non-surgical treatment modalities (e.g., standard irradiation, certain anticancer drugs). The role of the tumor O2 status in radio-/chemotherapy and its impact on relevant tumor biological characteristics of tumors are summarized in Table 1.

Multi-data models translations in interoperable information systems

1996

Interoperation of heterogeneous and autonomous information systems has traditionally been hampered by semantic differences in their data models. In this paper, we address the problem by defining a methodology called TIME, which is based on an extensible meta model. Its key features are: a set of meta-types which can be used to represent the syntax and the semantics of data modeling concepts, a knowledge base of transformation rules that map a meta-type into other meta-types, and an inference engine which uses the transformation rules to translate schema from source to target models. The extensibility of the meta-model is achieved by organizing the meta-types into a generalization hierarchy …

Forming Processes Design Oriented to Prevent Ductile Fractures

1996

During cold forming processes ductile fractures are sometimes encountered, depending on the operating parameters and on the material properties and determining the production of defective components to be discarded; for this reason the development of a general approach for the prediction of this type of defects is particularly suitable and this aim has been pursued by a large number of researchers in the last two decades. In the paper the most important and diffused models are described and analysed in order to outline the advantages offered by each of them. Some applications to typical metal forming processes are presented, carrying out a comparison between the numerical predictions and th…

DNA-gehalt der tumorzelle

1996

Aufgrund der hohen Morbiditat und Mortalitat nach Leberresektion wegen eines hepatozellularen Karzinoms ist es sinnvoll, prognostisch relevante Faktoren zu evaluieren, um die Patienten zu definieren, die von einer Resektion profitieren um den anderen das Risiko eines komplikationstrachtigen Eingriffs zu ersparen. Am archivierten paraffineingebetteten Tumormaterial von 21 Patienten mit einem hepatozellularen Karzinom wurde nach Leberresektion mittels bildanalytischer DNA-Analyse die Ploidie bestimmt. Im DNA-Histogramm fanden sich diploide, hypotriploide, triploide, hypertriploide, tetraploide und nicht naher klassifizierbare aneuploide Tumoren. Es fand sich eine statistisch signifikante Korr…

Integrated Treatment Model for First-Contact Patients with a Schizophrenia-Type Psychosis: The Finnish API Project

1996

This paper presents the background, rationale, set-up and first results of the Finnish API study, whose aim was to investigate the use of a psychotherapeutically oriented and familycentred treatment model for acute psychosis in different treatment settings, and especially the role of neuroleptic drug treatment when working along the principles of the integrated treatment model. Six psychiatric catchment areas from different parts of the country participated by collecting a material of 136 first-contact patients with a schizophrenia-type psychosis. More than half of the patients received a formal diagnosis from the schizophrenia group at the initial examination, and more than one-third a dia…

Plasmavolumenverschiebung und Veränderungen der zentralen Hämodynamik nach Okklusion der A. mesent. sup. und anschließender Reperfusion

1996

Im Schweinemodell wurde die Veranderung des Plasmavolumens bei verschiedenen therapeutischen Ansatzen des Reperfusionsschocks nach 2-stundiger Okklusion der A. mesent. sup. untersucht (keine Therapie, 5–50 μg Dopamin, 40 ml/kg KG isotone Reperfusion in 30 Min., 5 ml/kg KG 7,5% NaCl/10% HAES in 5 Min.). Der Plasmavolumenverlust von >30% in der Kontroll- und Dopamingruppe wurde nur durch die isotone Reperfusion vollstandig ausgeglichen. Die hyperton/hyperonkotische Therapie (-16% PV-Verlust) wies aber ein signifikant verbessertes HZV auf.

PECAM-1 expression in human mesothelial cells: an in vitro study.

1996

Mesothelial cells are actively involved in inflammatory processes by expressing a set of cell adhesion molecules (CAMs). Transmigration of leukocytes into inflamed tissues requires a chemotactic stimulus and engagement of platelet-endothelial cell adhesion molecule-1 (PECAM-1). To investigate the kinetics involved in peritonitis, pure cultures of mesothelial cells are necessary. In previous studies, we have found that human mesothelial cells (HOMES) show a weak constitutive expression of PECAM-1, which cannot be further stimulated by cytokines. It is known that all serous cavities and body fluids contain numerous macrophages which strongly express this adhesion molecule. To identify the cel…

Molecular mechanisms in developmental biology.

1996

Some general molecular mechanisms underlying development are described. Namely: those involved in the differentiation of the R7 receptor in Drosophila embryonic retina; those involved in the determination of embryonic axes and in polar cell differentiation, in Drosophila; those involved in the determination of the AB and P cell lineage and in vulva differentiation in Caenorhabditis embryos.

Evaluation of Distance Education : Cost-Effectiveness

1996

This entry attempts to present the state of the art on the question of the cost-effectiveness analysis of distance teaching systems. It x-publicationlocationes especially two problems : the rapid evolution of information technologies introduces continuous changes in the combination of pedagogical inputs, from both a content and a cost point of view ; in addition, the new information technologies are also adopted within traditional face to face teaching, which leads to a reduction of the differencies between both modes of teaching delivery, and promotes some sort of convergence between the two systems.

Nuevo taxon del género "Pilosella" Hill "(Compositae)", procedente de la provincia de Soria

1996

Génesis y desarrollo de la fiscalidad concejil en el País Vasco durante la Edad Media (1140-1550)

1996

Los orígenes de la organización del estado moderno: la Corona de Aragón en el sistema político de los Reyes Católicos

1996

Une approche macro-économétrique interrégionale appliquée de la solidarité entre les territoires français

1996

International audience; Redistribution among French region : an interregional macro-modelling essay. First we start on a general survey of French regional economic equilibrium in a dualistic sense : is there any convergence between Paris region and the other parts of the national territory ? Things must be considered separately as they involve primary allocation (wages, entrepreneurial revenue) or redistribution process. On the medium term the redistribution bonus is more and more oriented towards non central regions, partly due to economic reason but also as an impact of national income policies. After a general summary of the modelling process uses here as a tool, we present some macro-ev…

Mathematical modelling of physical phenomena

1996

The word “physics” is derived from the Greek “fysis” which means nature. Physics investigates fundamental natural phenomena and thus physical knowledge has a very general character. This is also the reason why physics penetrates other areas including electrical engineering.

Netzwerkansatz als Forschungsparadigma im Rahmen der Untersuchung interorganisationaler Unternehmensbeziehungen

1996

In der Wissenschaft wie in der Praxis stellt sich immerwahrend die Frage, in welchen Kontexten Problemstellungen zweckmasig zu behandeln sind. Die ubergreifende Beantwortung dieser Frage ist schwierig — wenn uberhaupt moglich —, unterliegt doch die Festlegung eines Annahmenrahmens, welcher eine Problemstellung betrifft, einem Trade-off zwischen weitgehender Erfassung des Problems und seiner befriedigenden Losung.

19. gadsimta latgaliešu gramatikas

1996

Studi storico-religiosi sulla Sicilia antica

1996

Gli studi moderni sui culti e i miti della Sicilia antica: vecchie e nuove piste di ricerca. Prospettive metodologiche e apporti dell'archeologia e dell'epigrafia.

The great landslide at Portella Colla (Madonie, Sicily)

1996

The South Western area of the Madonie Mountains is affected by large landslides; the major one developed starting from Portella Colla down to the Imera Settentrionale river, for a maximum length of about 6.2 km in a NE-SW direction. The study of the landslide, with the aim of reconstructing the geological, geomorphological and evolutionary aspects, has been carried out using integrated methodologies, including some geophysical investigations (in particular geoelectrical prospecting). The landslide is complex and characterized by superficial and deep gravitational deformations. The movement began in the Upper Pliocene and it is still active. The origin and evolution of the landslide are link…

Static and Dynamic Properties of Adsorbed Chains at Surfaces:  Monte Carlo Simulation of a Bead-Spring Model

1996

The adsorption of flexible polymers from dilute solution in good solvents at attractive walls is studied by Monte Carlo simulation of a coarse-grained off-lattice model, varying chain length N and ...

Slow Dielectric Relaxation of Supercooled Liqutos Investigated by Nonresonant Spectral Hole Burning

1996

ABSTRACTWhen supercooled propylene carbonate and glycerol are subjected to a large-amplitude, low-frequency electric field, a spectral hole develops in their dielectric relaxation that is significantly narrower than their bulk response. This observation of nonresonant spectral hole burning establishes that the non-Debye response is due to a distribution of relaxation times. Refilling of the spectral hole occurs abruptly, indicative of a single recovery rate that corresponds to the peak in the distribution. The general shape of the spectral hole is preserved during recovery, indicating negligible interaction between the degrees of freedom that responded to the field. All relevant features in…

Properties of sea urchin coelomocyte agglutinins

1996

We examined some biological activities of a 200-kDa glycoprotein, referred to as Paracentrotus lividus vitellogenin, contained both in the coelomic fluid and in a subpopulation of coelomocytes called «colourless spherula cells». Cell-free coelomic fluid, coelomocyte lysate and supernatant obtained after coelomocyte washings were assayed for hemagglutinating activity. All samples agglutinated rabbit erythrocytes in a calcium-dependent way. The comparison between the electrophoretic patterns of erythrocyte lysates, before and after incubation with the coelomic fluid, revealed that a 200-kDa band was obtained from membranes of agglutinated erythrocytes. In addition, polyclonal antibodies again…

La ejemplaridad como recurso narrativo en las Crónicas del Canciller Ayala

1996

Tipologia de parlants en una comunitat de parla amb interrupció de la transmissió lingüística intergeneracional

1996

The article deals with the different kinds of speakers that emerge when language transmission failure arises between consecutive generations. The case is exemplified through the speech community of the city of Alacant, where we can distinguish four kinds of speakers, from the ones who know very well the local variety of Catalan to the ones who only understand this variety and whose first language is Spanish. In between we have the main concern of our study, the precarious speakers, distributed in two categories according to their skill in the use of Catalan, which has become their second language.

Eléments de Réflexion sur l'Approche Cognitive et Expérientielle de l'Inférence du Goût

1996

Alambique : didáctica de las ciencias experimentales

1996

Resumen tomado de la publicación Tanto desede el currículo escolar prescriptivo como desde las orientaciones para la elaboración de los proyectos de centro, se indica la necesidad de incorporar las líneas transversales, pero este proceso no siempre es fácil. Desde la reflexión de los autores, se plantea un análisis de las posibles estrategias de integración de la educación para la salud, igualmente válidas para otras líneas transversales, de forma que cada centro pueda decidir la manera de abordarla más acorde con sus posibilidades reales y con sus características contextuales. Cataluña ESP

Stalin y el retrato oficial en la Unión Soviética de entreguerras

1996

Real-time Control of Metallurgic Processes

1996

The careful control of the liquid metal solidification and the solid shell growth is of central importance in all metallurgic processes. These have a considerable influence on the formation of cracks and other defects which can be formed in the cast material. To ensure defect free products, the liquid metal is to be cooled down according to a pattern which depends i.e. on metal grade, product dimension, cooling speed and machine design. On the other hand, the control of the liquid/solid interface is a key element in optimising the liquid solidification with respect to good productivity. So, the heat transfer plays a very important role in metallurgic casting processes, especially when casti…

Avulsión de la tuberosidad anterior de la tibia asociada a rotura del tendón cuadricipital

1996

Se presenta 1 caso de fractura-avulsión de la tuberosidad anterior de la tibia asociada a rotura del tendón cuadricipital en un varón de 16 años. Tras el tratamiento quirúrgico de la fractura tuberositaria, y a pesar de haber pasado inicialmcnte inadvertida la lesión tendinosa, el resultado final a los 9 meses ha sido satisfactorio. A case of avulsion-fracture of the anterior tibial tubercle associated with rupture of the cuadricipital tendon in a 16-ycars-old boy is presented. After surgical treatment, in spite of having overlooked initially the tendinous lesion, the functional result at 9 months follow-up has been satisfactory.

An upper limit for Br(Z°→ggg) from symmetric 3-jet hadronic decays.

1996

An upper limit for BR(Z0 → 3g) is obtained from a correlation method, which distinguishes statistically between quark and gluon jets by using the difference in their charged particle multiplicity distributions. From the sample of threefold symmetric three-jet events collected by the DELPHI experiment at LEP during 1991¿1994, the 95% confidence level upper limit is deduced to be: BR(Z0 → 3g) ≤ 1.6 × 10−2 for the JADE and BR(Z0 → 3g) ≤ 1.5 × 10−2 for the DURHAM jet-finder.

Terapia visual con paciente de baja visión

1996

El caso expuesto es de una joven de 14 años con baja visión, que al encontrarse en plena adolescencia y además de vivenciar los cambios físicos y psíquicos que conlleva, se encuentra con una importancia limitación visual que no ha sido aceptada. La terapia visual se planteó con dos objetivos fundamentales: 1) reforzar habilidades visual como motilidad ocular, fijaciones, visión periférica y memoria visual. 2) mejorar el proceso de la información visual. Al finalizar este tratamiento esta joven ha mejorado el rendimiento escolar y lo que tal vez sea más importante: acepta mejor su deficiente visión.

Effects of fusaric acid on cells from tomato cultivars resistant or susceptible toFusarium oxysporum f. sp.Lycopersici

1996

Cell suspension cultures were set up from two tomato cultivars, one resistant, (‘Rio grande’) and one susceptible (‘63.5’) toFusarium oxysporum f. sp.lycopersici. Growth rates of the two cell cultures were comparable. Toxicity of fusaric acid, expressed as the fresh weight loss, was analyzed: It was significant in both cases after 10 h, but toxicity was twice as high for ‘63.5’ suspension cells. In the same way, electrolyte leakage caused by fusaric acid was three times more important for ‘63.5’ suspension cells. Moreover, fusaric acid treatment resulted in an acidification of the extracellular medium for ‘63.5’ suspension cells (0.4 pH unit), whereas an alkalization was observed for ‘Rio g…

Observation of charmless hadronic B decays

1996

Four candidates for charmless hadronic B decay are observed in a data sample of four million hadronic Z decays recorded by the ALEPH detector at LEP. The probability that these events come from background sources is estimated to be less than 10(-6). The average branching of weakly decaying B hadrons (a mixture of B-d(0), B-s(0) and Lambda(b) weighted by their production The average branching ratio of weakly decaying B hadrons (a mixture of B-d(0) cross sections and lifetimes, here denoted B) into two long-lived charged hadrons (pions, kaons or protons) is measured to be Br(B-->h(+)h(-))=(1.7(-0.7)(+1.0)+/-0.2)x10(-5). The relative branching fraction Br(B-d(s)(0)-->pi(+)pi(-)(K-))/Br(B-d(s)(…

Keski-Pohjanmaan alueellinen maatalousstrategia

1996

'I verbi forti in anglosassone: interferenze tra I e II classe'

1996

Aportaciones a la flora aragonesa I

1996

El tema de la comunicación en el último Calvino

1996

El presente artículo analiza la magia de la lectura que suscita en el lector la obra "Il Castello dei destini incrociati" de Italo Calvino.